Brigitte Tardy-Poncet, Emmanuel de Maistre, Claire Pouplard, Emilie Presles, Martine Alhenc-Gelas, Dominique Lasne, Marie-Hélène Horellou, Christine Mouton, Anne Serre-Sapin, Anne Bauters, Philippe Nguyen, François Mullier, Julien Perrin, Grégoire Le Gal, Pierre-Emmanuel Morange, Lélia Grunebaum, Agnès Lillo-Le Louet, Ismail Elalamy, Yves Gruel, Andreas Greinacher, Thomas Lecompte, Bernard Tardy
BACKGROUND: Diagnosis of heparin-induced thrombocytopenia (HIT) requires pretest probability assessment and dedicated laboratory assays. OBJECTIVE: To develop a pretest score for HIT. DESIGN: Observational; analysis of prospectively collected data of hospitalized patients suspected with HIT (ClinicalTrials.gov NCT00748839). SETTING: Thirty-one tertiary hospitals in France, Switzerland, and Belgium. PATIENTS: Patients tested for HIT antibodies (2280 evaluable), randomly allocated to derivation and validation cohorts...
August 2021: Journal of Thrombosis and Haemostasis: JTH