Yoshifumi Ubara, Shigekazu Kurihara, Yoshiki Tsuchiya, Yuki Oba, Daisuke Ikuma, Hiroki Mizuno, Masayuki Yamanouchi, Tatsuya Suwabe, Atsuko Imase, Nobumitsu Shibata, Kei Kono, Keiichi Kinowaki, Kenichi Ohashi, Kentaro Ogata, Naoki Sawa
A 28-year-old woman with a 5-year history of untreated hypertension was admitted for respiratory distress, hemoptysis, and retinopathy. Computed tomography showed diffuse plaques in both lung fields. Acute kidney injury, hemolytic anemia, and thrombocytopenia were noted. Kidney biopsy showed thrombosis with fibrinoid necrosis and edematous intimal thickening and luminal narrowing of the small renal artery, indicating thrombotic microangiopathy; the majority of glomeruli were collapsed. After 8 weeks of treatment with antihypertensive drugs, serum creatinine decreased to 1...
March 28, 2024: CEN Case Reports