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https://www.readbyqxmd.com/read/29352460/pelvic-floor-muscle-function-and-quality-of-life-in-post-menopausal-women-with-and-without-pelvic-floor-dysfunction
#1
Isabella Parente Ribeiro Frota, Adriana Bombonato Oliveira Rocha, José Ananias Vasconcelos Neto, Camila Teixeira Moreira Vasconcelos, Thais Fontes De Magalhaes, Sara Arcanjo Lino Karbage, Kathiane Lustosa Augusto, Simony Lira Do Nascimento, Jorge Millem Haddad, Leonardo Robson Pinheiro Sobreira Bezerra
This study aims to compare pelvic floor muscle (PFM) function in post-menopause women with and without pelvic floor dysfunction (PFD) and the relationship between PFM function and quality of life MATERIAL AND METHODS: a case-control study with 216 post-menopause women with (n=126) and without PFD (n=90). PFM function was assessed by digital vaginal palpation using PERFECT scale. Specific quality of life was evaluated by King's Health Questionnaire for women with urinary incontinence and Prolapse Quality-of-Life Questionnaire for women with pelvic organ prolapse...
January 20, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29352230/histology-immunohistochemistry-and-in-situ-hybridization-reveal-overlooked-ebola-virus-target-tissues-in-the-ebola-virus-disease-guinea-pig-model
#2
Timothy K Cooper, Louis Huzella, Joshua C Johnson, Oscar Rojas, Sri Yellayi, Mei G Sun, Sina Bavari, Amanda Bonilla, Randy Hart, Peter B Jahrling, Jens H Kuhn, Xiankun Zeng
Survivors of Ebola virus infection may become subclinically infected, but whether animal models recapitulate this complication is unclear. Using histology in combination with immunohistochemistry and in situ hybridization in a retrospective review of a guinea pig confirmation-of-virulence study, we demonstrate for the first time Ebola virus infection in hepatic oval cells, the endocardium and stroma of the atrioventricular valves and chordae tendinae, satellite cells of peripheral ganglia, neurofibroblasts and Schwann cells of peripheral nerves and ganglia, smooth muscle cells of the uterine myometrium and vaginal wall, acini of the parotid salivary glands, thyroid follicular cells, adrenal medullary cells, pancreatic islet cells, endometrial glandular and surface epithelium, and the epithelium of the vagina, penis and, prepuce...
January 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29351779/the-effect-of-twin-to-twin-delivery-time-intervals-on-neonatal-outcome-for-second-twins
#3
L Lindroos, A Elfvin, L Ladfors, U-B Wennerholm
BACKGROUND: The objective was to examine the effect of twin-to-twin delivery intervals on neonatal outcome for second twins. METHODS: This was a retrospective, hospital-based study, performed at a university teaching hospital in Western Sweden. Twin deliveries between 2008 and 2014 at ≥32 + 0 weeks of gestation, where the first twin was delivered vaginally, were included. Primary outcome was a composite outcome of metabolic acidosis, Apgar < 4 at 5 min or peri/neonatal mortality in the second twin...
January 19, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29350275/value-of-transperineal-ultrasound-on-the-observation-of-paravaginal-support
#4
Chaoran Dou, Qin Li, Tao Ying, Wen Shui, Yulin Yan, Yijia Luo, Xia Wang
OBJECTIVE: To explore the feasibility of three-dimensional (3D) transperineal ultrasound on the observation of paravaginal support in nulliparous and postpartum women. METHODS: Volume datasets were acquired in 50 nulliparous and 100 postpartum women using 3D transperineal ultrasound. Paravaginal supports were observed by studying the vaginal cross-sectional morphology. The extent of paravaginal support in specific level were evaluated by counting out at a 2 mm interval in tomographic ultrasound imaging mode in all subjects...
January 19, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29349716/detection-of-bovine-carriers-of-leptospira-by-serological-bacteriological-and-molecular-tools
#5
Melissa H Pinna, Gabriel Martins, Ana Paula Loureiro, Walter Lilenbaum
Bovine leptospirosis is an important infectious disease that causes reproductive problems and economic risks, particularly in the tropics. The present study aimed to determine the extent of Leptospira infection among bovines on a slaughterhouse from Rio de Janeiro, Brazil via serological, bacteriological, and molecular tests. Two hundred eight bovines were examined in total, and we obtained 208 blood samples for serology, 198 urine samples collected via direct bladder puncture for polymerase chain reaction (PCR) and culture, 208 kidney samples (one from each animal) for PCR and culture, and 92 vaginal fluid samples from sterile swabs for PCR and culture...
January 18, 2018: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/29347848/role-of-topical-oxytocin-in-improving-vaginal-atrophy-in-postmenopausal-women-a-randomized-controlled-trial
#6
H A Torky, A Taha, H Marie, E El-Desouky, O Raslan, A A Moussa, A M Ahmad, A Abo-Louz, S Zaki, T Fares, A Eesa
OBJECTIVE AND DESIGN: Prospective randomized controlled trial to test the effectiveness of topical oxytocin gel to improve vaginal atrophy in postmenopausal women. PATIENTS AND METHODS: A total of 140 postmenopausal women presenting with vaginal atrophy and who satisfied the inclusion and exclusion criteria were randomized into two groups each of 70 patients; they received intravaginal oxytocin gel or placebo gel for 30 days. Serum estrogen level, visual, colposcopic and histological vaginal examination were performed before and after treatment...
January 19, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/29346424/higher-sequence-diversity-in-the-vaginal-tract-than-in-blood-at-early-hiv-1-infection
#7
Katja Klein, Gabrielle Nickel, Immaculate Nankya, Fred Kyeyune, Korey Demers, Emmanuel Ndashimye, Cynthia Kwok, Pai-Lien Chen, Sandra Rwambuya, Art Poon, Marshall Munjoma, Tsungai Chipato, Josaphat Byamugisha, Peter Mugyenyi, Robert A Salata, Charles S Morrison, Eric J Arts
In the majority of cases, human immunodeficiency virus type 1 (HIV-1) infection is transmitted through sexual intercourse. A single founder virus in the blood of the newly infected donor emerges from a genetic bottleneck, while in rarer instances multiple viruses are responsible for systemic infection. We sought to characterize the sequence diversity at early infection, between two distinct anatomical sites; the female reproductive tract vs. systemic compartment. We recruited 72 women from Uganda and Zimbabwe within seven months of HIV-1 infection...
January 2018: PLoS Pathogens
https://www.readbyqxmd.com/read/29346340/disparities-in-preconception-health-indicators-%C3%A2-behavioral-risk-factor-surveillance-system-2013-2015-and-pregnancy-risk-assessment-monitoring-system-2013-2014
#8
Cheryl Robbins, Sheree L Boulet, Isabel Morgan, Denise V D'Angelo, Lauren B Zapata, Brian Morrow, Andrea Sharma, Charlan D Kroelinger
PROBLEM/CONDITION: Preconception health is a broad term that encompasses the overall health of nonpregnant women during their reproductive years (defined here as aged 18-44 years). Improvement of both birth outcomes and the woman's health occurs when preconception health is optimized. Improving preconception health before and between pregnancies is critical for reducing maternal and infant mortality and pregnancy-related complications. The National Preconception Health and Health Care Initiative's Surveillance and Research work group suggests ten prioritized indicators that states can use to monitor programs or activities for improving the preconception health status of women of reproductive age...
January 19, 2018: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/29346134/effect-of-maternal-body-mass-index-on-postpartum-hemorrhage
#9
Alexander J Butwick, Anisha Abreo, Brian T Bateman, Henry C Lee, Yasser Y El-Sayed, Olof Stephansson, Pamela Flood
BACKGROUND: It is unclear whether obesity is a risk factor for postpartum hemorrhage. The authors hypothesized that obese women are at greater risk of hemorrhage than women with a normal body mass index. METHODS: The authors conducted a cohort study of women who underwent delivery hospitalization in California between 2008 and 2012. Using multilevel regression, the authors examined the relationships between body mass index with hemorrhage (primary outcome), atonic hemorrhage, and severe hemorrhage (secondary outcomes)...
January 18, 2018: Anesthesiology
https://www.readbyqxmd.com/read/29345165/oral-contraceptive-pills-as-an-option-for-non-surgical-management-of-retained-products-of-conception-a-preliminary-study
#10
Anat Hershko Klement, Mitri Frederic, Yaakov Bentov, Paul Chang, Dan Nayot, Jigal Haas, Robert F Casper
Many Patients with persistent retained products of conception prefers to avoid surgical interventions, such as a dilatation and curettage (D&C) that might pose an additional future risk to their already compromised fertility or obstetric performance. The aim of this study was to the possibility of induced withdrawal bleeding following oral contraceptive administration as a non-surgical treatment for patients with persistent retained products of conception (RPOC). A retrospective study of patients presenting with retained products of conception (RPOC) after failed expectant management or after treatment with PGE1 was performed...
January 18, 2018: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29344846/evaluation-of-psychosocial-and-biological-parameters-in-women-seeking-for-a-caesarean-section-and-women-who-are-aiming-for-vaginal-delivery-a-cross-sectional-study
#11
Benjamin Tuschy, Sebastian Berlit, Paul Stützer, Stefanie Lis, Christian Schmahl, Ulf Baumgärtner, Marc Sütterlin
PURPOSE: To investigate psychosocial and biological parameters that may influence decision-making concerning the mode of delivery in women with caesarean section on maternal request (CSMR). METHODS: Two hundred and two women were enrolled prospectively. The study sample (n = 93) consisted of women who aimed for CSMR, the control sample were women who seeked for vaginal delivery (n = 109). Parturients of both samples were enrolled during the pre-birth counselling at the delivery room at the University Medical Centre Mannheim, University Heidelberg, Germany...
January 17, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29344403/maternal-morbidity-and-mortality-associated-with-retroperitoneal-haematomas-in-pregnancy
#12
Junaid Rafi, Haroona Khalil
Retroperitoneal haematomas in obstetrics are uncommon. The causes and pathogenesis of retroperitoneal haematomas lack clarity and the aim of this review is to recognise retroperitoneal haematomas as a separate entity from commonly seen vaginal and pelvic haematomas. It is time to raise awareness among obstetricians to recognise retroperitoneal haematomas as an important cause of maternal morbidity and mortality which requires high clinical suspicion and multidisciplinary input. As retroperitoneal haematomas are rare but can cause serious threat to maternal wellbeing, resources should be directed towards their management...
January 2018: JRSM Open
https://www.readbyqxmd.com/read/29344211/prevalence-of-hpv-infection-among-hiv-positive-and-hiv-negative-women-in-central-eastern-italy-strategies-of-prevention
#13
Edoardo Tartaglia, Katia Falasca, Jacopo Vecchiet, Giovanna Paola Sabusco, Giovanna Picciano, Roberto Di Marco, Claudio Ucciferri
The present cross-sectional-study aimed to determine the prevalence of human papillomavirus (HPV)-genotypes among human immunodeficiency virus (HIV)-positive and -negative women in Central/Eastern Italy, and to identify the optimal strategies for effective HPV-prevention in each group. A representative sample of HIV-negative (150/200) and -positive (50/200) women, who underwent cervico-vaginal-swabbing. Swabs were analysed for a cytological screening and for a HPV-DNA-genotyping-test. A total of 66/200 swabs resulted HPV-positive...
December 2017: Oncology Letters
https://www.readbyqxmd.com/read/29344080/effects-of-huang-bai-phellodendri-cortex-on-bone-growth-and-pubertal-development-in-adolescent-female-rats
#14
Sun Haeng Lee, Hyun Jeong Lee, Sung Hyun Lee, Young-Sik Kim, Donghun Lee, Jiu Chun, Jin Yong Lee, Hocheol Kim, Gyu Tae Chang
Background: To evaluate the effects of Huang Bai (Phellodendron amurense) on growth and maturation in adolescent female rats. Methods: Female Sprague-Dawley rats (28 days old; n = 72) were divided into six daily treatment groups: control (distilled water), Huang Bai (100 and 300 mg/kg), recombinant human GH (rhGH; 20 μg/kg), estradiol (1 μg/kg), and triptorelin (100 μg). Body weight, food intake, and vaginal opening were measured daily from postnatal day (PND) 28 to PND 43...
2018: Chinese Medicine
https://www.readbyqxmd.com/read/29344000/visible-near-infrared-spectroscopic-assessment-of-urogenital-tissue-in-premenopausal-and-postmenopausal-women
#15
Miranda A Farage, Tom Cambron, Kan-Zhi Liu
Background: A clinical study was conducted to evaluate the feasibility of using visible and near-infrared (NIR) spectroscopy as a potential noninvasive measure of genital skin health in premenopausal and postmenopausal women. Methods: A total of 45 female subjects (aged 21-70 years), all of whom gave fully informed consent to participate, were enrolled in the study and assigned to 1 of 3 groups: 15 premenopausal (Pre-M), 15 postmenopausal receiving hormone replacement therapy (Post-M HRT), and 15 postmenopausal receiving no form of hormone replacement therapy (Post-M non-HRT)...
2018: Clinical Medicine Insights. Women's Health
https://www.readbyqxmd.com/read/29343918/pediatric-pelvic-fracture-urethral-distraction-defect-causing-complete-urethrovaginal-avulsion
#16
Ritesh Kumar Singh, Devashish Kaushal, Nikhil Khattar, Rishi Nayyar, T Manasa, Rajeev Sood
Pelvic fracture with urethral injury in girls is an uncommon entity that is usually associated with concomitant vaginal lacerations. Management options vary from immediate exploration and urethral anastomosis to delayed urethroplasty. We report our experience of managing a 10-year old girl presenting 6 months after a pelvic fracture with urethrovaginal injury and a completely obliterated urethral meatus managed successfully with a single-stage bladder tube repair.
January 2018: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/29343577/cellular-and-humoral-immunity-protect-against-vaginal-zika-virus-infection-in-mice
#17
Jason M Scott, Tania J Lebratti, Justin M Richner, Xiaoping Jiang, Estefania Fernandez, Haiyan Zhao, Daved H Fremont, Michael S Diamond, Haina Shin
Zika virus (ZIKV), which can cause devastating disease in fetuses of infected pregnant women, can be transmitted by mosquito inoculation and sexual routes. Little is known about immune protection against sexually transmitted ZIKV. In this study, we show that previous infection through intravaginal or subcutaneous routes with a contemporary Brazilian strain of ZIKV can protect against subsequent intravaginal challenge with a homologous strain. Both routes of inoculation induced high titers of ZIKV-specific and neutralizing antibody in serum and the vaginal lumen...
January 17, 2018: Journal of Virology
https://www.readbyqxmd.com/read/29343220/antimicrobial-resistance-of-neisseria-gonorrhoeae-in-germany-low-levels-of-cephalosporin-resistance-but-high-azithromycin-resistance
#18
Susanne Buder, Sandra Dudareva, Klaus Jansen, Anna Loenenbach, Sergejs Nikisins, Andrea Sailer, Eva Guhl, Peter K Kohl, Viviane Bremer
BACKGROUND: The widespread antimicrobial resistance of Neisseria gonorrhoeae is a serious problem for the treatment and control of gonorrhoea. Many of the previously effective therapeutic agents are no longer viable. Because N. gonorrhoeae infections are not reportable in Germany, only limited data on disease epidemiology and antimicrobial susceptibility patterns are available. The Gonococcal Resistance Network (GORENET) is a surveillance project to monitor trends in the antimicrobial susceptibility of N...
January 17, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29343215/women-s-decision-making-processes-and-the-influences-on-their-mode-of-birth-following-a-previous-caesarean-section-in-taiwan-a-qualitative-study
#19
Shu-Wen Chen, Alison M Hutchinson, Cate Nagle, Tracey K Bucknall
BACKGROUND: Vaginal birth after caesarean (VBAC) is an alternative option for women who have had a previous caesarean section (CS); however, uptake is limited because of concern about the risks of uterine rupture. The aim of this study was to explore women's decision-making processes and the influences on their mode of birth following a previous CS. METHODS: A qualitative approach was used. The research comprised three stages. Stage I consisted of naturalistic observation at 33-34 weeks' gestation...
January 17, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29343134/implementation-of-vaginal-cleansing-prior-to-cesarean-delivery-to-decrease-endometritis-rates
#20
Laura Felder, Amanda Paternostro, Johanna Quist-Nelson, Jason Baxter, Vincenzo Berghella
BACKGROUND: Endometritis is a postpartum complication that is more common after cesarean delivery. It frequently requires intravenous antibiotic administration, prolonged hospital stays, and carries a risk of sepsis or abscess formation. Precesarean vaginal preparation has been shown to decrease the risk of endometritis in patients who have labored or have ruptured membranes. OBJECTIVE: The objective of this study was to assess the practical implementation of a protocol for vaginal cleansing prior to cesarean delivery and the subsequent effect on endometritis rates in a clinical setting...
January 17, 2018: Journal of Maternal-fetal & Neonatal Medicine
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