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pseudomona neurosurgery

Kirtilaxmi K Benachinmardi, R Ravikumar, B Indiradevi
INTRODUCTION: Biofilms are the source of persistent infections of many pathogenic microbes. They are responsible for nosocomial infection and also associated with many surgical conditions including indwelling medical devices such as ventriculoperitoneal shunt. A significant problem encountered in shunt procedures is obstruction followed by infection, with infection rate ranging from 2% to 27%, often with poor outcome. MATERIALS AND METHODS: This study was conducted in the Department of Neuromicrobiology at a tertiary neuroinstitute for 6 months from July 1 to December 31, 2014...
July 2017: Journal of Neurosciences in Rural Practice
Deepashu Sachdeva, Daljit Singh, Poonam Loomba, Amandeep Kaur, Monica Tandon, Ishu Bishnoi
BACKGROUND: Ventilator-associated pneumonia (VAP) is the most frequent nosocomial infection in patients receiving mechanical ventilation (MV) and contributes to a longer intensive care unit (ICU) stay, duration of MV, and a high morbidity and mortality. OBJECTIVE: The purpose of study was to determine the incidence of VAP in neurosurgery ICU patients and to assess the probable contributing neurosurgical risk factors like the site and nature of the lesion in the brain, the duration of surgery, blood loss during surgery, and infection elsewhere in the body, in the development of VAP...
July 2017: Neurology India
C J Parr, J Wheeler, A Sharma, C Smith
We describe the case of a 78-year-old female receiving adjuvant postsurgical chemotherapy for colon adenocarcinoma who spontaneously developed nosocomial Pseudomonas meningitis causing severe trismus. The patient was initially admitted for ileus, developing neck stiffness and trismus on the thirteenth day of admission. Cerebrospinal fluid grew pansensitive Pseudomonas aeruginosa. Magnetic resonance imaging of the brain was consistent with bilateral subacute infarcts secondary to meningitis. The patient responded well to 21 days of broad spectrum antimicrobial therapy modified to ceftazidime alone following speciation and sensitivity...
2017: Case Reports in Infectious Diseases
DongMei Yue, Caiping Song, Bo Zhang, Zhiyong Liu, Jin Chai, Yang Luo, Hao Wu
BACKGROUND: Exploring the distribution of nosocomial pathogens among different categories of intensive care units (ICUs) is critical to improving the management of health care-associated infection (HAI). Despite both single- and multicenter studies, the nature of the variations of HAIs within various ICUs remains inadequately evaluated. METHODS: Data on HAIs at our hospital during the period January 2010-December 2015 were collected from 8 ICUs, namely, respiratory, cardiovascular, neurology, neonatal, hematology, emergency, cardiothoracic surgery, and neurosurgery ICUs, at a tertiary hospital...
January 1, 2017: American Journal of Infection Control
Parmenion P Tsitsopoulos, Elias Iosifidis, Charalampos Antachopoulos, Dimitrios M Anestis, Ekaterini Karantani, Angeliki Karyoti, Georgios Papaevangelou, Eftychios Kyriazidis, Emmanuel Roilides, Christos Tsonidis
BACKGROUND: Data on nosocomial bloodstream infections (NBSI) in neurosurgery is limited. This study aimed to analyze the epidemiology, microbiology, outcome, and risk factors for death in neurosurgical patients with NBSI in a multidrug resistant setting. METHODS: Neurosurgical patients with a confirmed NBSI within the period 2003-2012 were retrospectively analyzed. NBSI was diagnosed when a pathogen was isolated from a blood sample obtained after the first 48 h of hospitalization...
September 2016: Acta Neurochirurgica
S K Shamaeva, U S Portnyagina, M V Edelstein, A A Kuzmina, S Maloguloval, N A Varfolomeeva
The authors present the results of long-term monitoring of metallo-beta-lactamase (MBL) producing strains of Pseudomonas aeruginosa in the Republican Hospital No 2 of Yakutsk, Russian Federation. Hospitals across Russia, as well as the rest of the world, face a rapid appearance and a virtually unchecked spread of multiresistant and panresistant nosocomial pathogens. Especially prevalent are multidrug-resistant isolates of P. aeruginosa, most often found among the patients of intensive care and intensive therapy units, as well as surgery departments...
2015: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
Wei-Ping Liu, Yong-Quan Tian, Yun-Ting Hai, Zhi-Nan Zheng, Qing-Ling Cao
BACKGROUND: To investigate the prevalence of nosocomial infections, the distribution of nosocomial infection sites, the use of antibiotic and the situation of detected nosocomial infection pathogens in the Inner Mongolia Autonomous Region of China from 2012 to 2014, to grasp the current conditions of regional nosocomial infections in timely, for the development of infection prevention and control measures to provide a basis for effective hospital. METHODS: A survey of the prevalence of nosocomial infections was conducted in target hospitals using the combination of a bedside survey and medical record review...
September 2015: Journal of Thoracic Disease
Linda R Taggart, Elizabeth Leung, Matthew P Muller, Larissa M Matukas, Nick Daneman
BACKGROUND: Antimicrobial decision making in intensive care units (ICUs) is challenging. Unnecessary antimicrobials contribute to the development of resistant pathogens, Clostridium difficile infection and drug related adverse events. However, inadequate antimicrobial therapy is associated with mortality in critically ill patients. Antimicrobial stewardship programs are increasingly being implemented to improve antimicrobial prescribing, but the optimal approach in the ICU setting is unknown...
October 29, 2015: BMC Infectious Diseases
Swathi Chidambaram, M Nathan Nair, Shyam Sundar Krishnan, Ling Cai, Weiling Gu, Madabushi Chakravarthy Vasudevan
OBJECTIVE: Postoperative central nervous system infections (PCNSIs) are rare but serious complications after neurosurgery. The purpose of this study was to examine the prevalence and causative pathogens of PCNSIs at a modernized, resource-limited neurosurgical center in South Asia. METHODS: A retrospective analysis was conducted of the medical records of all 363 neurosurgical cases performed between June 1, 2012, and June 30, 2013, at a neurosurgical center in South Asia...
December 2015: World Neurosurgery
S Pai, L Bedford, R Ruramayi, S H Aliyu, J Sule, D Maslin, D A Enoch
BACKGROUND: Pseudomonas aeruginosa is a rare cause of meningitis and ventriculitis but is generally associated with significant morbidity and mortality. AIM: We sought to determine the epidemiology, risk factors and outcome of meningitis and ventriculitis due to P. aeruginosa at our institution in order to inform preventive strategies and treatment guidelines. METHODS: Retrospective study of all patients with a positive cerebrospinal fluid (CSF) culture admitted to a tertiary care hospital over 18 years...
February 2016: QJM: Monthly Journal of the Association of Physicians
Sassan Keshavarzi, Matthew MacDougall, Dzenan Lulic, Aimen Kasasbeh, Michael Levy
INTRODUCTION: Oxidized regenerated cellulose has a long history of safe and effective use in the surgical setting. Surgicel Original, Fibrillar and Nu-Knit absorbable hemostats are composed of oxidized regenerated cellulose and are sterile, absorbable knitted fabrics that are flexible and adhere readily to bleeding surfaces. The purpose of this paper is to discuss neurosurgical applications for these absorbable hemostatic agents. METHODS: The authors reviewed the literature and described their clinical experience with Surgicel hemostatic products...
June 2013: Wounds: a Compendium of Clinical Research and Practice
J Smetana, B Čečetková, R Chlíbek
OBJECTIVE: In 2005-2010, a nosocomial infection prevalence study was conducted in 12 university hospitals, namely at the departments of surgery, urology, neurology, cardiology, neurosurgery, otorhinolaryngology, and traumatology. The primary objective was to evaluate the overall epidemiological situation of nosocomial infections (NI) at the highest risk departments of selected healthcare facilities in the Czech Republic and to characterize the NI detected. METHODS: To collect data, a questionnaire survey method was used, as it suited the routine operation conditions in healthcare facilities and was inexpensive, easy to understand, reproducible, and repeatable if needed...
November 2014: Epidemiologie, Mikrobiologie, Imunologie
Heng Zhou, Xinghu Zhang
AIM: Our aim was to study the clinical features of postoperative meningitis after neurosurgery and identify the factors affecting the duration of treatment. METHODS: This retrospective study assessed 283 patients with postoperative bacterial meningitis in the Neurosurgery Department of Beijing Tiantan Hospital, Beijing, People's Republic of China, between January and December 2012. Patients' clinical data were reviewed, and multivariate logistic regression analysis was used to identify the factors associated with a prolonged treatment course...
2014: Neuropsychiatric Disease and Treatment
Sónia Gonçalves Pereira, Margarida Marques, João Pereira, Olga Cardoso
Multidrug-resistant (MDR) Pseudomonas aeruginosa isolates are increasing worldwide and greatly limit therapeutic options, particularly when considering extensively drug-resistant (XDR) or pandrug-resistant isolates. The resistance profile of P. aeruginosa isolates from a Portuguese central hospital was surveyed during 10 years (n=3,778). About 39.9% were classified as MDR and 2.9% as XDR. Statistical analysis (Mann-Whitney test and regression modeling) revealed a decrease in total MDR rates over time but an increase in XDR rates...
April 2015: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
Liu Yan, Ye Qing, Jin Xingyi, Qiao Hongbo
Our objective is to analyze the etiology and antibiotics resistance rate of multiple drug-resistant bacteria infection in elderly patients with stroke-associated pneumonia from Neurosurgery Department, providing a reference for clinical treatment. Sputum of 372 elderly patients with stroke-associated pneumonia (SAP) from Neurosurgery Department was collected for sputum culture and drug sensitivity test, and pathogenic bacteria distribution and drug resistance rate of antibiotics were discussed. Among 372 pathogenic bacteria, there were 95 cases with Gram-positive cocci, the percentage was 15...
March 2015: Cell Biochemistry and Biophysics
Emine Alp, Dilek Altun, Fatma Cevahir, Safiye Ersoy, Ozlem Cakir, Mary-Louise McLaws
BACKGROUND: The rates of hand hygiene improvement and health care-associated infections (HAIs) were evaluated after the introduction in 2004 of an infection surveillance and prevention program at a university teaching hospital in a low- to middle-income country. METHODS: Data on hand hygiene compliance, HAI rate, multiresistant organisms, and antibiotic consumption in 4 adult intensive care units (ICUs; medical, general surgery, anesthesiology and reanimation, and neurosurgery) were collected retrospectively for each year from 2004 to 2012...
October 2014: American Journal of Infection Control
S S Pradeep Kumar, H V Easwer, A Maya Nandkumar
BACKGROUND: Medical devices are an essential part of modern health-care, but its usage has led to the emergence of medical device associated infections otherwise known as Foreign-Body related infections (FBRIs). This is caused by bacterial adhesion and biofilm formation on their surfaces which act as a nidus of infection. These biofilms are resistant to antibacterial agents and host immune response. The antibiotics which are useful in treating planktonic forms cannot clear the biofilm and the device must usually be removed to resolve the infection...
October 2013: Journal of the Association of Physicians of India
P P Saramma, K Krishnakumar, P K Dash, P S Sarma
BACKGROUND: Interventional studies on the effect of alcohol-based hand rub on ventilator-associated pneumonia (VAP) among neurosurgical patients are scarce. AIM: To observe the effect of alcohol-based hand rub on tracheobronchial colonization and VAP after elective neurosurgical procedures. MATERIALS AND METHODS: An interventional study using a "before-after" design in a tertiary care center in Kerala. Two 9-month study periods were compared; between these periods, an infection control protocol incorporating an alcohol-based hand rub was implemented for a period of 3 months and continued thereafter...
October 2011: Indian Journal of Critical Care Medicine
Dwarakanath Srinivas, H B Veena Kumari, Sampath Somanna, Indiradevi Bhagavatula, Chandramouli Bangalore Anandappa
INTRODUCTION: Meningitis is the most dreaded cause of morbidity and mortality in neurosurgical patients. The reported incidence of postoperative meningitis is quite varied 0.5-8%. MATERIAL AND METHODS: The study cohort included all the patients who underwent neurosurgery at the department of neurosurgery, National Institute of Mental Health and Neurological Sciences, Bangalore, India over a period of seven years (2001 - 2007). Patients with culture positive meningitis were included for analysis...
March 2011: Neurology India
Pedro Laguna-del Estal, Pablo García-Montero, María Agud-Fernández, María López-Cano Gómez, Ana Castañeda-Pastor, Carlos García-Zubiri
INTRODUCTION: Gram-negative bacilli are causative agents of bacterial meningitis in the neonatal period but rarely cause meningitis in adults without risk factors. AIM: To report on meningitis due to gram-negative bacilli (MGNB) in adults diagnosed in a hospital over a 25-year period. PATIENTS AND METHODS: We reviewed the medical records of all patients with an age > or = 14 years who had been diagnosed with MGNB between 1982 and 2006. RESULTS: Fifteen cases of MGNB are included (10...
April 16, 2010: Revista de Neurologia
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