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https://www.readbyqxmd.com/read/29761024/relationships-between-activity-and-well-being-in-people-with-parkinson-s-disease
#1
Felicitas Ehlen, Katharina Schindlbeck, Lisa Nobis, André Maier, Fabian Klostermann
Objectives: The complex symptomatology of Parkinson' disease (PD) usually goes along with reduced physical activity. Previous studies have indicated positive effects of activating therapies on patients' well-being. This study, therefore, examined how activity in daily life is related to patients' subjective condition. Materials and Methods: Twenty-one PD patients rated their condition every two hours during two routine days and documented the duration and type of their activities (based on the PRISCUS-Physical Activity Questionnaire) during the respective time intervals...
May 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29760292/-targeting-transcellular-transport-of-%C3%AE-synuclein-for-developing-disease-modifying-therapies-for-synucleinopathy
#2
Takafumi Hasegawa
Parkinson's disease (PD) is the second most common neurodegenerative disorder and it is characterized by progressive physical disability along with a variety of non-motor symptoms. Drugs that replenish dopamine can partly alleviate the motor symptoms; however, they do not cure the disease itself. Therefore, there is an urgent need for disease modifying therapies that would delay or prevent neurodegeneration. Increasing evidence suggests that α-synuclein, a key molecule in PD, is secreted into the extracellular environment and can be transported from cell-to-cell, thereby affecting the physiological state of the neighboring cells in a prion-like manner...
May 2018: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/29745627/neurophysiological-and-clinical-effects-of-blinfolded-balance-training-bbt-in-parkinson-s-disease-patients-a-preliminary-study
#3
Sonia Bonnì, Viviana Ponzo, Marco Tramontano, Alex Martino Cinnera, Carlo Caltagirone, Giacomo Koch, Antonella Peppe
BACKGROUND: Recent evidence support the hypothesis that rehabilitative strategies based on sensorimotor stimulation in the neurorehabilitation of Parkinson's Disease (PD) may be useful to improve gait in PD patients. AIM: We supposed that sensorimotor stimulation produce modulation of Anticipatory Postural Adjustments (APAs) arising from the supplementary motor area (SMA). We aimed to investigate the clinical and neurophysiological effects of a blindfolded balance training (BBT)...
May 9, 2018: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29729611/accuracy-of-wearable-physical-activity-trackers-in-people-with-parkinson-s-disease
#4
Robyn M Lamont, Hannah L Daniel, Caitlyn L Payne, Sandra G Brauer
INTRODUCTION: The purpose of this study was to determine the accuracy of the Fitbit Charge HR™ and Garmin vívosmart® HR in measuring steps and reflecting intensity of activity in people with Parkinson's disease (PD). METHODS: Thirty-three people with mild-moderate PD performed six, two-minute indoor walks at their self-selected walking pace, and at target cadences of 60, 80, 100, 120 and 140 beats/min. A 500 m outdoor walk with terrain challenges was also performed...
April 24, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29700848/non-pharmacological-therapies-for-sleep-disturbances-in-people-with-parkinson-s-disease-a-systematic-review
#5
REVIEW
JuHee Lee, Yonji Kim, YieLin Kim
AIM: To determine the effectiveness of non-pharmacological therapies for sleep disturbances in people with Parkinson's disease. BACKGROUND: Sleep disturbances, which are common in people with Parkinson's disease, may diminish their quality of life. Non-pharmacological therapies are preferred over pharmacological therapies for improving sleep quality, owing to fewer adverse effects. DESIGN: Systematic literature review. DATA SOURCES: A systematic search of eight databases and hand searching was conducted for papers published between 1 January 1 2000 - 1 January 2016...
April 27, 2018: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29670571/electromyographical-gait-characteristics-in-parkinson-s-disease-effects-of-combined-physical-therapy-and-rhythmic-auditory-stimulation
#6
Christopher A Bailey, Federica Corona, Mauro Murgia, Roberta Pili, Massimiliano Pau, Julie N Côté
Background: In persons with Parkinson's disease (PD), gait dysfunctions are often associated with abnormal neuromuscular function. Physical therapy combined with auditory stimulation has been recently shown to improve motor function and gait kinematic patterns; however, the underlying neuromuscular control patterns leading to this improvement have never been identified. Objectives: (1) Assess the relationships between motor dysfunction and lower limb muscle activity during gait in persons with PD; (2) Quantify the effects of physical therapy with rhythmic auditory stimulation (PT-RAS) on lower limb muscle activity during gait in persons with PD...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29667433/association-between-physical-fitness-cardiovascular-risk-factors-and-parkinson-s-disease
#7
Jan Müller, Jonathan Myers
Objective Exercise is a cornerstone of therapy for Parkinson's disease. This study addressed the association between physical fitness and the onset of Parkinson's disease and association with cardiovascular risk factors. Patients and methods Male veterans ( N = 7347, 59.0 ± 11.2 years) from the Veterans Exercise Testing Study cohort were evaluated. Physical fitness was measured objectively by maximal exercise testing. Onset of Parkinson's disease was abstracted from the Veterans Affairs computerized patient records system...
January 1, 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29660960/are-functional-mobility-tests-responsive-to-group-physical-therapy-intervention-in-individuals-with-parkinson-s-disease
#8
Gessyca Spagnuolo, Christina D C M Faria, Bruna Adriana da Silva, Angélica Cristiane Ovando, Joyce Gomes-Osman, Alessandra Swarowsky
BACKGROUND: The Timed up and go test (TUG), the Five times sit-to-stand test (FTSTS) and the Bed Mobility test (BMT) are widely used in clinical practice for Parkinson Disease (PD). However, no reported studies have evaluated the responsiveness to group physical therapy intervention (GPTI). OBJECTIVE: To verify if TUG, FTSTS and BMT were responsive to GPTI. METHODS: Thirty individuals with PD were assessed prior to and after an 8-week evidence-based GPTI...
April 7, 2018: NeuroRehabilitation
https://www.readbyqxmd.com/read/29628812/exercise-therapy-for-a-patient-with-parkinson-disease-and-back-pain-a-case-report
#9
Christina L Rosarion
Objective: The purpose of this report is to describe an exercise intervention for an elderly patient with Parkinson disease with a chief complaint of lower back pain. Clinical Features: The patient was an 85-year-old man who had been diagnosed with Parkinson disease and kyphosis. Back pain was preventing him from carrying out activities of daily living. He was referred for physical therapy for treatment to reduce lower back pain and increase function. An initial examination consisted of testing flexibility and range of motion and administering a pain severity scale and a Lower Extremity Functional Index (LEFI); the patient's initial LEFI score was 14/80...
March 2018: Journal of Chiropractic Medicine
https://www.readbyqxmd.com/read/29607671/the-applied-effectiveness-of-clay-art-therapy-for-patients-with-parkinson-s-disease
#10
Young-Sil Bae, Dong-Hee Kim
This study investigates how clay art therapy affects Parkinson's disease patients' overall mental and physical condition as well as future treatment potentiality. The research was nonequivalent control groups pre and post study. A total of 54 patients with Parkinson's disease (control = 28, experimental = 26) were recruited from 3 setting locations in South Korea. Test measures were completed before and after the 16 sessions. The experimental group received two 80-minute evaluations per week for 8 weeks. Demographic information: hand dexterity, self-expression, mood depression, and quality of life measurements...
January 2018: J Evid Based Integr Med
https://www.readbyqxmd.com/read/29569562/a-new-tool-to-adapt-the-treatment-of-parkinson-s-disease-patients-in-nursing-homes
#11
Christian Geny, Claudia Verna, Alexia Arifi, Ernestine Ferreira, Choukri Boubakri, Hubert Blain
Parkinson's disease (PD) is a common condition in nursing home (NH) residents. The primary treatment for Parkinson's disease is levodopa therapy to relieve motor symptoms and maximize physical function. Non-motor symptoms are highly prevalent in NH residents with Parkinson's disease and dramatically decrease quality of life. Choices in drug treatment need to take into account the complex interactions between aging, comorbidity and non-motor symptoms. Optimal management requires expertise and cooperative effort from prescribing neurologists and nursing home health professionals...
March 1, 2018: Gériatrie et Psychologie Neuropsychiatrie du Vieillissement
https://www.readbyqxmd.com/read/29484198/physical-therapy-and-deep-brain-stimulation-in-parkinson-s-disease-protocol-for-a-pilot-randomized-controlled-trial
#12
Ryan P Duncan, Linda R Van Dillen, Jane M Garbutt, Gammon M Earhart, Joel S Perlmutter
Background: Subthalamic nucleus deep brain stimulation (STN-DBS) reduces tremor, muscle stiffness, and bradykinesia in people with Parkinson's Disease (PD). Walking speed, known to be reduced in PD, typically improves after surgery; however, other important aspects of gait may not improve. Furthermore, balance may worsen and falls may increase after STN-DBS. Thus, interventions to improve balance and gait could reduce morbidity and improve quality of life following STN-DBS. Physical therapy (PT) effectively improves balance and gait in people with PD, but studies on the effects of PT have not been extended to those treated with STN-DBS...
2018: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29473781/prediction-of-depression-and-anxiety-via-patient-assessed-tremor-severity-not-physician-reported-motor-symptom-severity-in-patients-with-parkinson-s-disease-or-essential-tremor-who-have-undergone-deep-brain-stimulation
#13
Rebecca L Achey, Erin Yamamoto, Daniel Sexton, Christine Hammer, Bryan S Lee, Robert S Butler, Nicolas R Thompson, Sean J Nagel, Andre G Machado, Darlene A Lobel
OBJECTIVE Deep brain stimulation (DBS) is an effective therapy for movement disorders such as idiopathic Parkinson's disease (PD) and essential tremor (ET). However, some patients who demonstrate benefit on objective motor function tests do not experience postoperative improvement in depression or anxiety, 2 important components of quality of life (QOL). Thus, to examine other possible explanations for the lack of a post-DBS correlation between improved objective motor function and decreased depression or anxiety, the authors investigated whether patient perceptions of motor symptom severity might contribute to disease-associated depression and anxiety...
February 23, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29471030/neuroprotective-effects-of-fecal-microbiota-transplantation-on-mptp-induced-parkinson-s-disease-mice-gut-microbiota-glial-reaction-and-tlr4-tnf-%C3%AE-signaling-pathway
#14
Meng-Fei Sun, Ying-Li Zhu, Zhi-Lan Zhou, Xue-Bing Jia, Yi-Da Xu, Qin Yang, Chun Cui, Yan-Qin Shen
Parkinson's disease (PD) patients display alterations in gut microbiota composition. However, mechanism between gut microbial dysbiosis and pathogenesis of PD remains unexplored, and no recognized therapies are available to halt or slow progression of PD. Here we identified that gut microbiota from PD mice induced motor impairment and striatal neurotransmitter decrease on normal mice. Sequencing of 16S rRNA revealed that phylum Firmicutes and order Clostridiales decreased, while phylum Proteobacteria, order Turicibacterales and Enterobacteriales increased in fecal samples of PD mice, along with increased fecal short-chain fatty acids (SCFAs)...
February 20, 2018: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/29458923/a-bicentric-controlled-study-on-the-effects-of-aquatic-ai-chi-in-parkinson-disease
#15
Sagrario Pérez-de la Cruz
OBJECTIVES: Various exercise strategies have been suggested to address movement deficits in order to improve motor function and quality of life for individuals in the early or moderate stages of Parkinson disease. The purpose is to evaluate the effects of an aquatic Ai Chi intervention on balance, gait speed and quality of life of patients. DESIGN AND INTERVENTION: Twenty-nine people with Parkinson disease participated in this pilot study. People were randomized into (1) aquatic Ai Chi program (experimental group) and (2) a dry land conventional Western physical therapy intervention (control group)...
February 2018: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/29428927/dancing-for-healthy-aging-functional-and-metabolic-perspectives
#16
Josianne Rodrigues-Krause, Mauricio Krause, Alvaro Reischak-Oliveira
Context • Dancing has been used as a form of exercise to improve functional and metabolic outcomes during aging. The field lacks randomized, clinical trials (RCTs) evaluating metabolic outcomes related to dance interventions, but dancing may be a form of exercise that could induce positive effects on the metabolic health of older adults. However, primary studies seem very heterogonous regarding the trial designs, characteristics of the interventions, the methods for outcomes assessments, statistical powers, and methodological quality...
February 10, 2018: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/29394208/caring-interactions-in-secondary-prevention-programs-a-qualitative-inquiry-of-individuals-with-parkinson-s-disease
#17
Lindsey E Greviskes, Leslie Podlog, Maria Newton, Leland E Dibble, Ryan D Burns, Wanda Pillow, Morgan S Hall, Christopher Hammer
BACKGROUND AND PURPOSE: With Parkinson's disease (PD) prevalence rates steadily increasing and long-term adherence to regular physical activity and exercise often difficult to achieve, it is imperative to investigate factors promoting adherence to secondary prevention programs (SPP) that help limit the progression of motor and nonmotor signs and symptoms of the disease. Caring interactions between patients and their rehabilitation team may be particularly germane to individuals with PD, given the physical and psychosocial issues that often accompany this disease (eg, loss of physical function, depression, apathy, and cognitive impairments)...
February 1, 2018: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/29366918/the-role-of-rehabilitation-in-subjects-with-progressive-supranuclear-palsy-a-narrative-review
#18
REVIEW
Domenico Intiso, Michelangelo Bartolo, Andrea Santamato, Filomena Di Rienzo
Progressive supranuclear palsy (PSP) is a progressive neurodegenerative disorder caused by the deposition of abnormal proteins in neurons of the basal ganglia that limit motor ability, resulting in disability and reduced quality of life. So far, no pharmacologic therapy has been developed, and the treatment remains symptomatic. The aim of the present study was to perform a systematic investigation of the literature, and to determine the types and effects of rehabilitative interventions used for PSP. A search of all studies was conducted in MEDLINE/PubMed, the Cochrane Central Register of Controlled Trials, CINAHL, and EMBASE...
January 31, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29225912/effects-of-virtual-rehabilitation-versus-conventional-physical-therapy-on-postural-control-gait-and-cognition-of-patients-with-parkinson-s-disease-study-protocol-for-a-randomized-controlled-feasibility-trial
#19
Keyte Guedes Silva, Tatiana Beline De Freitas, Flávia Doná, Fernando Freitas Ganança, Henrique Ballalai Ferraz, Camila Torriani-Pasin, José Eduardo Pompeu
Background: There is an association among postural instability, gait dysfunction, and cognitive impairment in subjects with Parkinson's disease (PD). Difficulty in dividing attention, response inhibition, and visuospatial attention deficiencies may contribute to the impairment of motor performance during daily activities. There are strong evidences that physical therapy can prevent physical and cognitive decline in individuals with PD. Recently, the European Physiotherapy Guideline (EPG) was developed based on randomized clinical trials about the effectiveness of the physical therapy to improve the functional deficiencies of individuals with PD...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29206708/use-of-a-telehealth-system-to-enhance-a-home-exercise-program-for-a-person-with-parkinson-disease-a-case-report
#20
Charlotte A Chatto, Paul T York, Catherine P Slade, Scott M Hasson
BACKGROUND AND PURPOSE: This case addresses feasibility of a home-based telehealth system to enhance home exercise program (HEP) adherence for a patient with Parkinson disease (PD). We describe START-System for Technology-Augmented Rehabilitation and Training-and discuss outcomes after integrating START into the HEP component of an established therapy protocol, Lee Silverman Voice Technique BIG (LSVT BIG). CASE DESCRIPTION: The participant was a 67-year-old woman with PD at Hoehn and Yahr Stage II...
January 2018: Journal of Neurologic Physical Therapy: JNPT
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