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https://www.readbyqxmd.com/read/28199497/racial-differences-in-associations-of-blood-pressure-components-in-young-adulthood-with-incident-cardiovascular-disease-by-middle-age-coronary-artery-risk-development-in-young-adults-cardia-study
#1
Yuichiro Yano, Jared P Reis, Yacob G Tedla, David C Goff, David R Jacobs, Stephen Sidney, Hongyan Ning, Kiang Liu, Philip Greenland, Donald M Lloyd-Jones
Importance: Data are sparse regarding which blood pressure (BP) components in young adulthood optimally determine cardiovascular disease (CVD) by middle age. Objectives: To assess which BP components best determine incident CVD events in young adults and determine whether these associations vary by race and age at BP measurement. Design, Setting, and Participants: Using data from the Coronary Artery Risk Development in Young Adults (CARDIA) study, this study assessed the longitudinal race-stratified associations between BP and cardiovascular outcomes...
February 15, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28196265/association-of-coronary-artery-calcium-in-adults-aged-32-to-46-years-with-incident-coronary-heart-disease-and-death
#2
John Jeffrey Carr, David R Jacobs, James G Terry, Christina M Shay, Stephen Sidney, Kiang Liu, Pamela J Schreiner, Cora E Lewis, James M Shikany, Jared P Reis, David C Goff
Importance: Coronary artery calcium (CAC) is associated with coronary heart disease (CHD) and cardiovascular disease (CVD); however, prognostic data on CAC are limited in younger adults. Objective: To determine if CAC in adults aged 32 to 46 years is associated with incident clinical CHD, CVD, and all-cause mortality during 12.5 years of follow-up. Design, Setting, and Participants: The Coronary Artery Risk Development in Young Adults (CARDIA) Study is a prospective community-based study that recruited 5115 black and white participants aged 18 to 30 years from March 25, 1985, to June 7, 1986...
February 8, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28195519/troponin-t-release-is-associated-with-silent-myocardial-ischaemia-in-black-men-the-sabpa-study
#3
Madelein E Griffiths, Leoné Malan, Rhena Delport, Marike Cockeran, Manja Reimann
Background High sensitivity cardiac troponin T (hs-cTnT) is a validated marker of myocardial damage and may reflect the degree of silent myocardial ischaemia (SMI) and ventricular strain. Our aim was to compare hs-cTnT levels in black and white South Africans taking SMI into consideration. We further explored the capability of hs-cTnT to predict the presence of compensatory systolic hypertension in this South African cohort. Methods A bi-ethnic sex cohort ( n = 404) with similar socioeconomic status (198 black participants and 206 white participants, aged 20-65 years) participated in this target population study where 24 h ambulatory blood pressure, electrocardiogram and overnight fasting cardiometabolic variables were measured...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28193605/potential-deaths-averted-and-serious-adverse-events-incurred-from-adoption-of-the-sprint-intensive-blood-pressure-regimen-in-the-u-s-projections-from-nhanes
#4
Adam P Bress, Holly Kramer, Rasha Khatib, Srinivasan Beddhu, Alfred K Cheung, Rachel Hess, Vinod K Bansal, Guichan Cao, Jerry Yee, Andrew E Moran, Ramon A Durazo-Arvizu, Paul Muntner, Richard S Cooper
Background -The Systolic Blood Pressure Intervention Trial (SPRINT) demonstrated a 27% reduction in all-cause mortality with a systolic blood-pressure (SBP) goal of <120 mmHg versus <140 mmHg among U.S. adults at high cardiovascular disease (CVD) risk but without diabetes, stroke, or heart failure. To quantify the potential benefits and risks of SPRINT intensive goal implementation, we estimated the deaths prevented and excess serious adverse events (SAEs) incurred if the SPRINT intensive SBP treatment goal was implemented in all eligible U...
February 13, 2017: Circulation
https://www.readbyqxmd.com/read/28193194/the-objective-physical-activity-and-cardiovascular-disease-health-in-older-women-opach-study
#5
Andrea Z LaCroix, Eileen Rillamas-Sun, David Buchner, Kelly R Evenson, Chongzhi Di, I-Min Lee, Steve Marshall, Michael J LaMonte, Julie Hunt, Lesley Fels Tinker, Marcia Stefanick, Cora E Lewis, John Bellettiere, Amy H Herring
BACKGROUND: Limited evidence exists to inform physical activity (PA) and sedentary behavior guidelines for older people, especially women. Rigorous evidence on the amounts, intensities, and movement patterns associated with better health in later life is needed. METHODS/DESIGN: The Objective PA and Cardiovascular Health (OPACH) Study is an ancillary study to the Women's Health Initiative (WHI) Program that examines associations of accelerometer-assessed PA and sedentary behavior with cardiovascular and fall events...
February 14, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28179490/paleolithic-and-mediterranean-diet-pattern-scores-are-inversely-associated-with-all-cause-and-cause-specific-mortality-in-adults
#6
Kristine A Whalen, Suzanne Judd, Marjorie L McCullough, W Dana Flanders, Terryl J Hartman, Roberd M Bostick
Background: Poor diet quality is associated with a higher risk of many chronic diseases that are among the leading causes of death in the United States. It has been hypothesized that evolutionary discordance may account for some of the higher incidence and mortality from these diseases.Objective: We investigated associations of 2 diet pattern scores, the Paleolithic and the Mediterranean, with all-cause and cause-specific mortality in the REGARDS (REasons for Geographic and Racial Differences in Stroke) study, a longitudinal cohort of black and white men and women ≥45 y of age...
February 8, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28179220/modifiable-risk-factors-versus-age-on-developing-high-predicted-cardiovascular-disease-risk-in-blacks
#7
Adam P Bress, Lisandro D Colantonio, John N Booth, Tanya M Spruill, Joseph Ravenell, Mark Butler, Amanda J Shallcross, Samantha R Seals, Kristi Reynolds, Gbenga Ogedegbe, Daichi Shimbo, Paul Muntner
BACKGROUND: Clinical guidelines recommend using predicted atherosclerotic cardiovascular disease (ASCVD) risk to inform treatment decisions. The objective was to compare the contribution of changes in modifiable risk factors versus aging to the development of high 10-year predicted ASCVD risk. METHODS AND RESULTS: A prospective follow-up was done of the Jackson Heart Study, an exclusively black cohort at visit 1 (2000-2004) and visit 3 (2009-2012). Analyses included 1115 black participants without high 10-year predicted ASCVD risk (<7...
February 8, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28157672/prevalence-and-risk-factors-of-taste-and-smell-impairment-in-a-nationwide-representative-sample-of-the-us-population-a-cross-sectional-study
#8
Gang Liu, Geng Zong, Richard L Doty, Qi Sun
OBJECTIVES: To estimate the prevalence of, and explore potential risk factors for, taste and smell dysfunction in the general population of the USA. DESIGN: A cross-sectional study. SETTING: A cross-sectional analysis of data collected in the National Health and Nutrition Examination Survey (NHANES 2013-2014). PARTICIPANTS: A total of 3519 men and women aged 40 years and older who participated in NHANES 2013-2014. MAIN OUTCOME MEASURES: Using the NHANES Pocket Smell Test, smell impairment was defined as failing to correctly identify 6 or more of the 8 odours...
November 9, 2016: BMJ Open
https://www.readbyqxmd.com/read/28154164/sex-differences-in-the-association-between-insulin-resistance-and-incident-coronary-heart-disease-and-stroke-among-blacks-without-diabetes-mellitus-the-jackson-heart-study
#9
Valery S Effoe, Lynne E Wagenknecht, Justin B Echouffo Tcheugui, Haiying Chen, Joshua J Joseph, Rita R Kalyani, Ronny A Bell, Wen-Chih H Wu, Ramon Casanova, Alain G Bertoni
BACKGROUND: Studies exploring the association between insulin resistance (IR) and cardiovascular disease in blacks have not been conclusive, especially for coronary heart disease (CHD). The McAuley index and homeostasis model assessment of IR (HOMA-IR) perform differently in predicting cardiovascular disease. We investigated this association in the Jackson Heart Study, a large longitudinal cohort of blacks. METHODS AND RESULTS: IR was estimated for 3565 participants without diabetes mellitus and cardiovascular disease at baseline using the McAuley index and HOMA-IR, and their associations with incident CHD and stroke (composite outcome) were compared...
February 2, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28153991/sex-based-differences-in-cardiometabolic-biomarkers
#10
Jeanney Lew, Monika Sanghavi, Colby R Ayers, Darren K McGuire, Torbjørn Omland, Dorothee Atzler, Maria O Gore, Ian Neeland, Jarett D Berry, Amit Khera, Anand Rohatgi, James A de Lemos
BACKGROUND: Few data are available comparing cardiovascular disease (CVD) biomarker profiles between women and men in the general population. We analyzed sex-based differences in multiple biomarkers reflecting distinct pathophysiological pathways, accounting for differences between women and men in CVD risk factors, body composition, and cardiac morphology. METHODS: A cross-sectional analysis was performed using data from the Dallas Heart Study, a multiethnic population-based study...
February 7, 2017: Circulation
https://www.readbyqxmd.com/read/28152767/understanding-the-comorbidome-and-its-effect-on-survival-in-colorectal-cancer
#11
Ernest Shen, Janet S Lee, Corrine E Munoz-Plaza, Carly Parry, Michael K Gould
: 210 Background: Effectively managing comorbidities is an essential component of high-quality cancer care. Evidence suggests colorectal cancer (CRC) patients with multiple comorbid conditions are less likely to complete standard treatments and can have lower rates of survival. In order to provide personalized care, it is critical to understand how comorbid conditions cluster within CRC patients. METHODS: We identified Kaiser Permanente Southern California CRC patients diagnosed with first malignancy between 01/01/2008 - 12/31/2013...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28147893/geography-race-ethnicity-and-physical-activity-among-men-in-the-united-states
#12
Elizabeth Kelley Sohn, Tichelle Porch, Sarah Hill, Roland J Thorpe
Engaging in regular physical activity reduces one's risk of chronic disease, stroke, cardiovascular disease, and some forms of cancer. These preventive benefits associated with physical activity are of particular importance for men, who have shorter life expectancy and experience higher rates of chronic diseases as compared to women. Studies at the community and national levels have found that social and environmental factors are important determinants of men's physical activity, but little is known about how regional influences affect physical activity behaviors among men...
February 1, 2017: American Journal of Men's Health
https://www.readbyqxmd.com/read/28131531/cognitive-decline-and-its-risk-factors-in-prevalent-hemodialysis%C3%A2-patients
#13
David A Drew, Daniel E Weiner, Hocine Tighiouart, Sarah Duncan, Aditi Gupta, Tammy Scott, Mark J Sarnak
BACKGROUND: Cognitive impairment is common in patients treated with hemodialysis. The trajectory of cognitive function and risk factors for cognitive decline remain uncertain in this population. STUDY DESIGN: Longitudinal cohort. SETTING & PARTICIPANTS: 314 prevalent hemodialysis patients. PREDICTORS: Age, sex, race, education level, hemodialysis vintage, cause of end-stage renal disease, and baseline history of cardiovascular disease...
January 26, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28129086/association-of-the-interaction-between-smoking-and-depressive-symptom-clusters-with-coronary-artery-calcification-the-cardia-study
#14
Allison J Carroll, Reto Auer, Laura A Colangelo, Mercedes R Carnethon, David R Jacobs, Jesse C Stewart, Rachel Widome, J Jeffrey Carr, Kiang Liu, Brian Hitsman
OBJECTIVE: Depressive symptom clusters are differentially associated with prognosis among patients with cardiovascular disease (CVD). Few studies have prospectively evaluated the association between depressive symptom clusters and risk for CVD. Previously, we observed that smoking and global depressive symptoms were synergistically associated with coronary artery calcification (CAC). The purpose of this study was to determine whether the smoking by depressive symptoms interaction, measured cumulatively over 25 years, differed by depressive symptom cluster (negative affect, anhedonia, and somatic symptoms) in association with CAC...
January 27, 2017: Journal of Dual Diagnosis
https://www.readbyqxmd.com/read/28127708/associations-between-hunter-type-a-b-personality-and-cardiovascular-risk-factors-from-adolescence-through-young-adulthood
#15
Benjamin D Pollock, Wei Chen, Emily W Harville, Lydia A Bazzano
PURPOSE: Type A personality, characterized by action-oriented tendencies, has been linked to cardiovascular disease in middle-aged and elderly adults. Alternatively, limited research has tested whether personality type A/B and cardiovascular (CVD) risk are linked prior to adulthood. Therefore, we used the Hunter-Wolf A/B personality score to determine whether personality type A/B is associated with traditional CVD risk factors during adolescence, and more importantly if personality type, or its individual type A components, are associated with cardiovascular risk through young adulthood...
January 26, 2017: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28118823/improving-heart-health-among-black-african-american-women-using-civic-engagement-a-pilot-study
#16
Alison G M Brown, Linda B Hudson, Kenneth Chui, Nesly Metayer, Namibia Lebron-Torres, Rebecca A Seguin, Sara C Folta
BACKGROUND: Despite increased risk for cardiovascular disease (CVD) and related conditions, evaluations of health interventions indicate that Black/African American women are less likely to benefit than their white counterparts and are not as likely to engage in behaviors that reduce CVD risk. The purpose of this study was to test the feasibility and effectiveness of civic engagement as an intervention strategy to address heart health in Black/African American women. METHODS: Using a quasi-experimental pre-post study design, civic engagement was tested by convening a convenience sample of self-identified Black/African American women, ages 30-70 years, English-speaking, and BMI ≥25...
January 24, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28110852/cardiac-troponin-t-as-early-marker-of-subclinical-cardiovascular-deterioration-in-black-hypertensive-women
#17
R Kruger, A E Schutte, C M C Mels, W Smith, J M van Rooyen, I M Kruger, C M T Fourie
BACKGROUND: Hypertensive heart disease is a rising concern, especially among black South African women. As high sensitivity cardiac troponin T (cTnT) is a marker of cardiomyocyte damage, we determined the potential link of (i) systemic endothelial dysfunction (reflected by urinary albumin-to-creatinine ratio), (ii) large artery stiffness, (iii) cardiac volume load (estimated by the N-terminal prohormone B-type natriuretic peptide (Nt-proBNP)), and (iv) ECG left ventricular hypertrophy in post-menopausal black women...
December 19, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28109473/competing-causes-of-death-in-the-head-and-neck-cancer-population
#18
Sean T Massa, Nosayaba Osazuwa-Peters, Kara M Christopher, Lauren D Arnold, Mario Schootman, Ronald J Walker, Mark A Varvares
PURPOSE/OBJECTIVES: The increasing survivorship of head and neck squamous cell carcinoma (HNSCC) comes with a risk of death from other causes, known as competing causes. The demographics of HNSCC are also evolving with increasing incidence of Human Papillomavirus (HPV) associated tumors. This study describes competing causes of death for the HNSCC population compared to the general population and identifies associated risk factors. METHODS: Adult patients with first mucosal HNSCC (2004-2011) were identified from the Surveillance, Epidemiology and End Result database...
February 2017: Oral Oncology
https://www.readbyqxmd.com/read/28104402/racial-and-ethnic-differences-in-the-polycystic-ovary-syndrome-pcos-metabolic-phenotype
#19
Lawrence Engmann, Susan Jin, Fangbai Sun, Richard S Legro, Alex J Polotsky, Karl R Hansen, Christos Coutifaris, Michael P Diamond, Esther Eisenberg, Heping Zhang, Nanette Santoro
BACKGROUND: Women with polycystic ovarian syndrome have a high prevalence of metabolic syndrome and type 2 diabetes mellitus. Blacks and Hispanics have a high morbidity and mortality due to cardiovascular disease and diabetes mellitus in the general population. Since metabolic syndrome is a risk factor for development of type 2 diabetes and cardiovascular disease, understanding any racial and ethnic differences in metabolic syndrome amongst women with polycystic ovarian syndrome is important for prevention strategies...
January 16, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28103061/cardiometabolic-mortality-by-supplemental-nutrition-assistance-program-participation-and-eligibility-in-the-united-states
#20
Zach Conrad, Colin D Rehm, Parke Wilde, Dariush Mozaffarian
OBJECTIVES: To investigate total and cause-specific cardiometabolic mortality among Supplemental Nutrition Assistance Program (SNAP) participants, SNAP-eligible nonparticipants, and SNAP-ineligible individuals overall and by age, gender, race/ethnicity, and other characteristics. METHODS: We performed a prospective study with nationally representative survey data from the National Health Interview Survey (2000-2009), merged with subsequent Public-Use Linked Mortality Files (2000-2011)...
March 2017: American Journal of Public Health
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