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Obesity and labor

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https://www.readbyqxmd.com/read/28528810/titration-of-intravenous-oxytocin-infusion-for-postdate-induction-of-labor-across-body-mass-index-groups
#1
Angela B Maeder, Susan C Vonderheid, Chang G Park, Aleeca F Bell, Barbara L McFarlin, Catherine Vincent, C Sue Carter
OBJECTIVE: To evaluate whether oxytocin titration for postdate labor induction differs among women who are normal weight, overweight, and obese and whether length of labor and birth method differ by oxytocin titration and body mass index (BMI). DESIGN: Retrospective cohort study. SETTING: U.S. university-affiliated hospital. PARTICIPANTS: Of 280 eligible women, 21 were normal weight, 134 were overweight, and 125 were obese at labor admission...
May 18, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/28489959/mood-disorders-in-adult-asthma-phenotypes
#2
Marina Labor, Slavica Labor, Iva Jurić, Vladimir Fijačko, Sanja Popović Grle, Davor Plavec
OBJECTIVE: Studies show high comorbidity of mood disorders in asthma. As asthma is a highly heterogeneous disease with different phenotypes it can be expected that there is a difference in this association with different asthma phenotypes. The aim of our cross-sectional study was to assess the association of specific asthma phenotypes with anxiety and/or depression and their impact on asthma control. METHODS: A cross-sectional study in 201 consecutive adult outpatients with asthma (≥18 years of age) was conducted...
May 10, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28484667/racial-ethnic-disparities-in-postpartum-hemorrhage-in-native-hawaiians-pacific-islanders-and-asians
#3
Scott A Harvey, Eunjung Lim, Krupa R Gandhi, Jill Miyamura, Kazuma Nakagawa
The objective of this study was to assess racial-ethnic differences in the prevalence of postpartum hemorrhage (PPH) among Native Hawaiians and other Pacific Islanders (NHOPI), Asians, and Whites. We performed a retrospective study on statewide inpatient data for delivery hospitalizations in Hawai'i between January 1995 and December 2013. A total of 243,693 in-hospital delivery discharges (35.0% NHOPI, 44.0% Asian, and 21.0% White) were studied. Among patients with PPH, there were more NHOPI (37.1%) and Asians (47...
May 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/28468839/human-relaxins-rlnh1-rlnh2-their-receptor-rxfp1-and-fetoplacental-growth
#4
Kelly Yamasato, Pai-Jong Stacy Tsai, James Davis, Sandra Yamamoto, Gillian Bryant-Greenwood
Relaxin, a systemic and placental hormone, has potential roles in fetoplacental growth. Human placenta expresses two RLN genes, RLNH1 and RLNH2. Maternal obesity is common and is associated with abnormal fetal growth. Our aims were to relate systemic and cord blood RLNH2, placental RLNs and their receptor (RXFP1) with fetoplacental growth in context of maternal body mass index, and associations with insulin-like growth factor 2 (IGF2) and vascular endothelial growth factor A (VEGFA) in the same placentas. Systemic, cord blood and placental samples were collected prior to term labor, divided by prepregnancy body mass index: underweight/normal (N=25) and overweight/obese (N=44)...
May 3, 2017: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/28465607/methods-for-quantifying-adipose-tissue-insulin-resistance-in-overweight-obese-humans
#5
K W Ter Horst, K A van Galen, P W Gilijamse, A V Hartstra, P F de Groot, F M van der Valk, M T Ackermans, M Nieuwdorp, J A Romijn, M J Serlie
BACKGROUND/OBJECTIVES: Insulin resistance of adipose tissue is an important feature of obesity-related metabolic disease. However, assessment of lipolysis in humans requires labor-intensive and expensive methods, and there is limited validation of simplified measurement methods. We aimed to validate simplified methods for the quantification of adipose tissue insulin resistance against the assessment of insulin sensitivity of lipolysis suppression during hyperinsulinemic-euglycemic clamp studies...
May 3, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28462873/maternal-obesity-and-obstetric-outcomes-in-a-tertiary-referral-center
#6
Gitana Ramonienė, Laima Maleckienė, Rūta Jolanta Nadišauskienė, Eglė Bartusevičienė, Dalia Regina Railaitė, Regina Mačiulevičienė, Almantas Maleckas
BACKGROUND AND AIM: Obese women are at an increased risk of various adverse pregnancy outcomes. The aim of our study was to evaluate the impact of obesity on maternal and neonatal outcomes in a tertiary referral center and to compare obstetric outcomes by the level of maternal obesity. MATERIALS AND METHODS: A cohort study included 3247 women with singleton gestations who gave birth at the Department of Obstetrics and Gynecology, Lithuanian University of Health Sciences, in 2010...
April 19, 2017: Medicina
https://www.readbyqxmd.com/read/28456503/novel-oxytocin-receptor-variants-in-laboring-women-requiring-high-doses-of-oxytocin
#7
Erin L Reinl, Zane A Goodwin, Nandini Raghuraman, Grace Y Lee, Erin Y Jo, Beakal M Gezahegn, Meghan K Pillai, Alison G Cahill, Cristina De Guzman Strong, Sarah K England
BACKGROUND: Although oxytocin commonly is used to augment or induce labor, it is difficult to predict its effectiveness because oxytocin dose requirements vary significantly among women. One possibility is that women requiring high or low doses of oxytocin have variations in the oxytocin receptor gene. OBJECTIVES: To identify oxytocin receptor gene variants in laboring women with low and high oxytocin dosage requirements. STUDY DESIGN: Term, nulliparous women requiring oxytocin doses of ≤4 mU/min (low-dose requiring, n = 83) or ≥20 mU/min (high-dose requiring, n = 104) for labor augmentation or induction provided consent to a postpartum blood draw as a source of genomic DNA...
April 26, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28453058/-socioeconomic-factors-conditioning-obesity-in-adults-evidence-based-on-quantile-regression-and-panel-data
#8
Karina L Temporelli, Valentina N Viego
Objective To measure the effect of socioeconomic variables on the prevalence of obesity. Factors such as income level, urbanization, incorporation of women into the labor market and access to unhealthy foods are considered in this paper. Method Econometric estimates of the proportion of obese men and women by country were calculated using models based on panel data and quantile regressions, with data from 192 countries for the period 2002-2005.Levels of per capita income, urbanization, income/big mac ratio price and labor indicators for female population were considered as explanatory variables...
August 2016: Revista de Salud Pública
https://www.readbyqxmd.com/read/28446997/endoscopic-submucosal-dissection-and-endoscopic-mucosal-resection-for-early-stage-esophageal-cancer
#9
REVIEW
Bo Ning, Mohamed M Abdelfatah, Mohamed O Othman
Mortality from esophageal cancer remains high despite advances in medical therapy. Although the incidence of squamous cell carcinoma of the esophagus remains unchanged, the incidence of the esophageal adenocarcinoma has increased over time. Gastroesophageal reflux disease (GERD and obesity are contributing factors to the development of Barrett's esophagus and subsequent development of adenocarcinoma. Early recognition of the disease can lead to resection of esophageal cancer prior to the development of lymphovascular invasion...
March 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28421691/the-impact-of-maternal-employment-on-children-s-adiposity-evidence-from-china-s-labor-policy-reform
#10
Young Jo, Qing Wang
BACKGROUND: China has experienced a rapid growth in childhood adiposity in recent years. Although a large number of studies examine the effect of maternal employment on children's adiposity in developed countries, only a few studies investigate the issue in developing countries. Moreover, existing studies tend to suffer from a potential endogeneity issue. AIMS: We provide new evidence on the causal effect of maternal employment on children's adiposity in China. MATERIALS AND METHODS: We employ a difference-in-difference strategy that takes advantage of China's 1995 legislative change to labor regulations, which reduced the number of workdays from 6 to 5 days per week...
April 19, 2017: Health Economics
https://www.readbyqxmd.com/read/28409493/obesity-in-pregnancy-a-novel-concept-on-the-roles-of-adipokines-in-uterine-contractility
#11
REVIEW
Judit Hajagos-Tóth, Eszter Ducza, Reza Samavati, Sandor G Vari, Robert Gaspar
Obesity is a global health problem even among pregnant women. Obesity alters quality of labor, such as preterm labor, prolonged labor, and higher oxytocin requirements in pregnant women. The most important factors to play a role in the altered gestational period and serve as drug targets to treat the consequences are female sexual hormones, calcium channels, adrenergic system, oxytocin, and prostaglandins. However, we have limited information about the impact of obesity on the pregnant uterine contractility and gestation time...
April 14, 2017: Croatian Medical Journal
https://www.readbyqxmd.com/read/28389056/effects-of-adipokines-and-obesity-on-uterine-contractility
#12
REVIEW
Henri Azaïs, Audrey Leroy, Louise Ghesquiere, Philippe Deruelle, Sandy Hanssens
Obesity is a major public health problem. The prevalence of obesity has significantly increased in developed countries, particularly in France with an overall increase of 76% over the last 15 years. In pregnant women, obesity is associated with alterations in the quality of labor, such as delayed onset of labor, a higher rate of prolonged pregnancies, prolonged labor, and higher oxytocin requirements. There is also an increased prevalence of Cesarean sections, particularly during the active phase of labor, and perinatal complications (postpartum hemorrhage)...
January 13, 2017: Cytokine & Growth Factor Reviews
https://www.readbyqxmd.com/read/28382838/potato-chips-cookies-and-candy-oh-my-public-commentary-on-proposed-rules-regulating-competitive-foods
#13
Lauren M Dinour, Antoinette Pole
BACKGROUND: The Healthy, Hunger-Free Kids Act of 2010 authorizes the U.S. Department of Agriculture (USDA) to establish nutritional standards for all foods sold in schools participating in federally funded meal programs. These foods, known as competitive foods, are commonly found in school cafeterias, vending machines, fundraisers, and snack bars and are associated with unhealthy dietary patterns. However, little is known about the regulatory process and opportunities for public participation to improve school food...
April 1, 2017: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/28347147/oxytocin-augmentation-in-spontaneously-laboring-nulliparous-women
#14
Nicole S Carlson, Elizabeth J Corwin, Nancy K Lowe
BACKGROUND: Synthetic oxytocin, the primary tool for labor augmentation, is less effective among obese women, leading to more unplanned cesarean deliveries for slow labor progress. It is not known if obese women require higher doses of oxytocin due to maternal, fetal, or labor factors related to maternal obesity. OBJECTIVES: This study had two main objectives: (1) examine the influence of maternal body mass index (BMI) on hourly doses of oxytocin from augmentation initiation until vaginal delivery in obese women; and (2) examine the influence of other maternal, fetal, and labor factors on hourly doses of oxytocin in obese women...
January 1, 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28335768/leisure-sedentary-time-is-differentially-associated-with-hypertension-diabetes-mellitus-and-hyperlipidemia-depending-on-occupation
#15
Man Sup Lim, Bumjung Park, Il Gyu Kong, Songyong Sim, So Young Kim, Jin-Hwan Kim, Hyo Geun Choi
BACKGROUND: Sedentary behavior is considered an independent cause of cardio-metabolic diseases, regardless of physical activity level and obesity. Few studies have reported the association between leisure sedentary time and cardio-vascular diseases in terms of occupation. METHODS: We performed a cross-sectional study using data from the Korean Community Health Survey (KCHS) for 240,086 participants assessed in 2011 and 2013. Occupation was categorized into four groups: farmer or fisherman, laborer, and soldier (Group I); service worker, salesperson, technician, mechanic, production worker, and engineer (Group II); manager, expert, specialist, and clerk (Group III); and unemployed (Group IV)...
March 23, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28332220/perspectives-on-risk-assessment-of-risk-profiles-and-outcomes-among-women-planning-community-birth-in-the-united-states
#16
Marit L Bovbjerg, Melissa Cheyney, Jennifer Brown, Kim J Cox, Lawrence Leeman
BACKGROUND: There is little agreement on who is a good candidate for community (home or birth center) birth in the United States. METHODS: Data on n=47 394 midwife-attended, planned community births come from the Midwives Alliance of North America Statistics Project. Logistic regression quantified the independent contribution of 10 risk factors to maternal and neonatal outcomes. Risk factors included: primiparity, advanced maternal age, obesity, gestational diabetes, preeclampsia, postterm pregnancy, twins, breech presentation, history of cesarean and vaginal birth, and history of cesarean without history of vaginal birth...
March 22, 2017: Birth
https://www.readbyqxmd.com/read/28328535/the-assessment-of-labor-a-brief-history
#17
Wayne R Cohen, Emanuel A Friedman
In the 1930s, investigators in the US, Germany and Switzerland made the first attempts to quantify the course of labor in a clinically meaningful way. They emphasized the rupture of membranes as a pivotal event governing labor progress. Attention was also placed on the total number of contractions as a guide to normality. Beginning in the 1950s, Friedman determined that changes in cervical dilatation and fetal station over time were the most useful parameters for the assessment of labor progress. He showed all normal labors had similar patterns of dilatation and descent, differing only in the durations and slopes of their component parts...
March 22, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28316560/lysopc-acyl-c16-0-is-associated-with-brown-adipose-tissue-activity-in-men
#18
Mariëtte R Boon, Leontine E H Bakker, Cornelia Prehn, Jerzy Adamski, Maarten J Vosselman, Ingrid M Jazet, Lenka M Pereira Arias-Bouda, Wouter D Marken van Lichtenbelt, Ko Willems van Dijk, Patrick C N Rensen, Dennis O Mook-Kanamori
INTRODUCTION: Brown adipose tissue (BAT) recently emerged as a potential therapeutic target in the treatment of obesity and associated disorders due to its fat-burning capacity. The current gold standard in assessing BAT activity is [(18)F]FDG PET-CT scan, which has severe limitations including radiation exposure, being expensive, and being labor-intensive. Therefore, indirect markers are needed of human BAT activity and volume. OBJECTIVE: We aimed to identify metabolites in serum that are associated with BAT volume and activity in men...
2017: Metabolomics: Official Journal of the Metabolomic Society
https://www.readbyqxmd.com/read/28292470/sexual-dimorphism-in-the-effect-of-maternal-obesity-on-antioxidant-defense-mechanisms-in-the-human-placenta
#19
LaShauna Evans, Leslie Myatt
INTRODUCTION: Maternal obesity creates an adverse intrauterine environment, negatively impacts placental respiration, is associated with a higher incidence of pregnancy complications and programs the offspring for disease in adult life in a sexually dimorphic manner. We defined the effect of maternal obesity and fetal sex on pro- and anti-oxidant status in placenta and placental mitochondria. METHODS: Placental villous tissue was collected at term via c-section prior to labor from four groups of patients based on fetal sex and prepregnancy/1st trimester body mass index: lean - BMI 22...
March 2017: Placenta
https://www.readbyqxmd.com/read/28253924/withania-somnifera-leaf-alleviates-cognitive-dysfunction-by-enhancing-hippocampal-plasticity-in-high-fat-diet-induced-obesity-model
#20
Shaffi Manchanda, Gurcharan Kaur
BACKGROUND: Sedentary lifestyle, psychological stress and labor saving devices in this current society often disrupts the energy gain and expenditure balance leading to obesity. High caloric diet is associated with the high prevalence of cognitive dysfunction and neuropsychiatric disorders in addition to cardiovascular and metabolic abnormalities. The present study was aimed to elucidate the potential beneficial effect of dry leaf powder of Withania somnifera (Ashwagandha) in preventing the cognitive decline associated with diet induced obesity...
March 3, 2017: BMC Complementary and Alternative Medicine
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