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methicillin sensitive staphylococcus aureus

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https://www.readbyqxmd.com/read/28926634/nasal-and-pharyngeal-carriage-of-methicillin-resistant-staphylococcus-sciuri-among-hospitalised-patients-and-healthcare-workers-in-a-serbian-university-hospital
#1
Ivana Cirkovic, Jasmina Trajkovic, Tomasz Hauschild, Paal Skytt Andersen, Adebayo Shittu, Anders Rhod Larsen
There has been a paucity of data on methicillin-resistant Staphylococcus sciuri (MRSS) epidemiology in European healthcare settings. The aim of the study was to determine the prevalence of nasal and pharyngeal carriage and diversity of MRSS among inpatients and healthcare workers (HCWs) in the largest healthcare centre in Serbia, and to assess performance of different methods for MRSS screening. Nasal and pharyngeal swabs were obtained from 195 patients and 105 HCWs in different departments. Each swab was inoculated directly onto MRSA-ID, oxacillin-resistance screening agar and mannitol salt agar (MSA) with 2 mg/L of oxacillin...
2017: PloS One
https://www.readbyqxmd.com/read/28922066/the-effect-of-lysozyme-on-reducing-biofilms-by-staphylococcus-aureus-pseudomonas-aeruginosa-and-gardnerella-vaginalis-an-in-vitro-examination
#2
Mirsada Hukić, Dzenita Seljmo, Amra Ramovic, Monia Avdić Ibrišimović, Serkan Dogan, Jasna Hukic, Elma Feric Bojic
Two basic questions about lysozyme activities on the selected microorganisms were investigated, namely whether lysozyme inhibits biofilm production and which concentrations of the enzyme have the ability to change the natural biofilm producing capacity of different strains of Staphylococcus aureus (methicillin sensitive and resistant), Streptococcus pyogenes, Pseudomonas aeruginosa, and Gardnerella vaginalis. The effect of lysozyme on biofilm formation capacities of 16 strains of selected microorganisms was investigated, whereby four testing replicates have been performed in vitro using the Test Tube method, and the potential of lysozyme to change biofilm forming capacities depending on its concentration, species, and strains of microorganisms is demonstrated...
September 18, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28903765/antimicrobial-resistance-among-pathogenic-bacteria-from-mink-neovison-vison-in-denmark
#3
Nanett Kvist Nikolaisen, Desireé Corvera Kløve Lassen, Mariann Chriél, Gitte Larsen, Vibeke Frøkjær Jensen, Karl Pedersen
BACKGROUND: For proper treatment of bacterial infections in mink, knowledge of the causative agents and their antimicrobial susceptibility patterns is crucial. The used antimicrobials are in general not registered for mink, i.e. most usage is "off-label". In this study, we report the patterns of antimicrobial resistance among pathogenic bacteria isolated from Danish mink during the period 2014-2016. The aim of this investigation was to provide data on antimicrobial resistance and consumption, to serve as background knowledge for new veterinary guidelines for prudent and optimal antimicrobial usage in mink...
September 13, 2017: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/28901792/methicillin-sensitive-staphylococcus-aureus-chorioamnionitis-and-foetal-death-after-mechanical-induction-of-labour-a-case-report
#4
Chibuike Godson Iruloh, Samantha Bonner, Ken Ma
No abstract text is available yet for this article.
September 13, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28900246/maldi-tof-ms-based-identification-and-molecular-characterization-of-food-associated-methicillin-resistant-staphylococcus-aureus
#5
H M Manukumar, S Umesha
Food-borne methicillin resistant Staphylococcus aureus (MRSA) is involved in two-fold higher mortality rate compared to methicillin susceptible S. aureus (MSSA). Eventhough Mysuru recognized as cleanest city in the world, prevalence of food contamination is not detailed. The aim is to screen food samples from Mysuru area and to characterize MRSA strain, employing MALDI-Biotyper, multiplex PCR to distinguish between MRSA and MSSA by PCR-coupled single strand conformation polymorphism (PCR-SSCP). Of all the food-borne pathogens, S...
September 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28899471/-a-report-of-two-children-with-fever-headache-and-purpura
#6
Hong-Bo Xu, Mei Tan, Jian Lu, Mao-Qiang Tian, Yan Chen
In this study, two school-aged children had an acute onset in spring and had the manifestations of fever, headache, vomiting, disturbance of consciousness, purpura and ecchymosis, and positive meningeal irritation sign. There were increases in peripheral white blood cells and neutrophils, but reductions in the hemoglobin level and platelet count in the two children. They had a significant increase in C-reactive protein. There were hundreds or thousands of white blood cells in the cerebrospinal fluid, mainly neutrophils...
September 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28898981/performance-of-the-cobas-mrsa-sa-test-for-simultaneous-detection-of-methicillin-susceptible-and-methicillin-resistant-staphylococcus-aureus-from-nasal-swabs
#7
Lance R Peterson, Christopher W Woods, Thomas E Davis, Zi-Xuam Wang, Stephen A Young, John C Osiecki, Michael A Lewinski, Oliver Liesenfeld
Objectives: Health care-associated methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus aureus (SA) infections are continuing problems. Rapidly determining the MRSA colonization status of a patient facilitates practice to reduce spread of MRSA clinical disease. Sensitive detection of all SA prior to surgery, followed by decolonization, can significantly reduce postoperative infection from this pathogen. Our goal was to validate a new automated assay for this testing. Methods: We compared performance of the cobas MRSA/SA Test on the cobas 4800 System to direct and enriched chromogenic culture using nasal swabs collected from patients at six United States sites...
August 1, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28893360/borderline-oxacillin-resistant-staphylococcus-aureus-borsa-a-more-common-problem-than-expected
#8
Maria M Hryniewicz, Katarzyna Garbacz
Borderline oxacillin-resistant Staphylococcus aureus (BORSA) represents a quite poorly understood and inadequately defined phenotype of methicillin resistance. BORSA strains show low, borderline resistance to penicillinase-resistant penicillins (PRPs), with oxacillin MICs typically equal to 1-8 µg ml-1, and in contrast to methicillin-resistant S. aureus (MRSA), do not have an altered penicillin-binding protein, PBP2a, encoded by the mecA or mecC gene. Their resistance is typically associated with hyperproduction of beta-lactamases or, in some cases, point mutations in PBP genes...
September 12, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28889756/occurrence-of-vancomycin-resistant-staphylococcus-aureus-in-the-oral-cavity-of-patients-with-dental-caries
#9
Sajith Vellappally, Darshan Devang Divakar, Abdulaziz Abdullah Al Kheraif, Ravikumar Ramakrishnaiah, Amer Alqahtani, M H N Dalati, Sukumaran Anil, Aftab Ahmed Khan, P R Harikrishna Varma
Oral streptococci are the major group of microbes isolated from oral microflora. They represent frequent pathogens of infective endocarditis (IE), and it is assumed that in most of the cases oral streptococci are acquired via mucosa layer of oral cavity. Staphylococcus aureus is also frequently isolated from IE as it accounts for 20%-30% of all cases. Vancomycin has been the most reliable therapeutic agent against infections caused by methicillin-resistant S. aureus (MRSA). The main objective of this study was to examine the occurrence of S...
September 11, 2017: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/28887643/clinical-predictors-of-methicillin-resistant-staphylococcus-aureus-in-nosocomial-and-healthcare-associated-pneumonia-a-multicenter-matched-case-control-study
#10
J Torre-Cisneros, C Natera, F Mesa, M Trikic, J Rodríguez-Baño
The situations in which coverage for methicillin-resistant Staphylococcus aureus (MRSA) in the empirical treatment of nosocomial pneumonia (NP) or severe healthcare-associated pneumonia (HCAP) is needed are poorly defined, particularly outside intensive care units (ICUs). Our aim was to characterize if the risk of MRSA NP/HCAP can be defined by clinical variables. We designed an observational, retrospective, multicenter, case-control study to analyze the association between defined clinical variables and risk of MRSA NP/HCAP in non-ICU patients using conditional multivariable logistic regression...
September 8, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28886942/remitting-infections-due-to-community-acquired-panton-valentine-leukocidin-producing-staphylococcus-aureus-in-the-milan-area
#11
Sara Giordana Rimoldi, Cristina Pagani, Erika Longhi, Valentina Di Cristo, Annamaria Di Gregorio, Alessandro Mancon, Pietro Zerbi, Cristina Gervasoni, Maria Rita Gismondo, Agostino Riva
One of the most important Staphylococcus aureus virulence factors is Panton-Valentine leukocidin (PVL). We describe an outbreak of recurrent cutaneous PVL infections in different members of three family clusters. Molecular investigations were performed to confirm the presence of the mecA and PVL genes and to assign the SCCmec type, sequence type (ST) and clonal relatedness. A strain of PVL-producing methicillin-resistant S. aureus (MRSA) was responsible for infection in two related families (A and B), and a third family (C) was infected with PVL-producing methicillin-sensitive S...
September 5, 2017: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/28886013/secondary-bacterial-infections-and-antibiotic-resistance-among-tungiasis-patients-in-western-kenya
#12
Ruth Monyenye Nyangacha, David Odongo, Florence Oyieke, Missiani Ochwoto, Richard Korir, Ronald Kiprotich Ngetich, Gladys Nginya, Olipher Makwaga, Christine Bii, Peter Mwitari, Festus Tolo
Tungiasis or jigger infestation is a parasitic disease caused by the female sand flea Tunga penetrans. Secondary infection of the lesions caused by this flea is common in endemic communities. This study sought to shed light on the bacterial pathogens causing secondary infections in tungiasis lesions and their susceptibility profiles to commonly prescribed antibiotics. Participants were recruited with the help of Community Health Workers. Swabs were taken from lesions which showed signs of secondary infection...
September 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28884051/anti-n-methyl-d-aspartate-receptor-nmdar-encephalitis-in-association-with-ovarian-teratoma
#13
Javaad Ahmad, Muhammad Saad Sohail, Amina Khan, Ahmed H Qavi, Pramod Gaudel, Mehr Zahid, Salman Assad
Anti-N-methyl-D-aspartate-Receptor (NMDAR) encephalitis is an autoimmune disorder with a multifaceted presentation that involves memory deficits, psychiatric symptoms, and autonomic instability. This case report describes the classic presentation of Anti-NMDAR encephalitis and highlights its association with ovarian teratomas. We present a 26 -year-old female who came in with new onset seizures and altered mentation who subsequently developed automatism. Electroencephalograms (EEG) showed left frontal spikes and right temporal delta activity...
July 5, 2017: Curēus
https://www.readbyqxmd.com/read/28874375/subinhibitory-dalbavancin-attenuates-exotoxin-production-from-methicillin-sensitive-and-methicillin-resistant-staphylococcus-aureus-in-vitro
#14
Sarah E Hobdey, Eva J Katahira, Pamela Dockstader, Stephen M Davidson, Laura Bond, Devin D Bolz, Amy E Bryant, Dennis L Stevens
This study investigates the effects of subinhibitory doses of the second-generation lipoglycopeptide antibiotic, dalbavancin, on Staphylococcus aureus toxin production in vitroS. aureus toxin production was compared with the natural glycopeptide antibiotic, vancomycin, and representative beta-lactam and oxazolidinone antibiotics. While neither dalbavancin nor vancomycin adversely increased toxin production, of these glycopeptide antibiotics, only dalbavancin significantly attenuated toxin production as subinhibitory concentrations...
September 5, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28870850/hypoprothrombinemia-and-severe-perioperative-haemorrhagic-complications-in-cardiac-surgery-patients-treated-with-high-dose-cefazolin-for-infective-endocarditis
#15
Emeline Angles, Christine Mouton, Justine Perino, Alain Remy, Alexandre Ouattara
Endocarditis is a serious and common disease that requires prolonged antimicrobial therapy. The recent shortage of oxacillin has led to the use of other antimicrobial agents such as cefazolin to treat endocarditis due to methicillin-sensitive Staphylococcus aureus. We describe four cases of life-threatening haemorrhagic complications (fatal in two cases) in patients treated with high-dose cefazolin. All of these patients with major bleeding presented with hypoprothrombinemia secondary to hypovitaminosis K. This adverse event may be due to inhibition of vitamin K epoxide reductase and/or gamma-glutamyl-carboxylase by the 2-methyl-1,2,3-thiadiazol-5-thiol group of cefazolin...
September 1, 2017: Anaesthesia, Critical Care & Pain Medicine
https://www.readbyqxmd.com/read/28866692/frequency-and-molecular-epidemiology-of-panton-valentine-leukocidin-gene-in-staphylococcus-aureus-colonising-hiv-infected-patients
#16
Z Mohd-Zain, S F A Mohd-Nawi, A Adnan, S Kumar
BACKGROUND: HIV-infected patients pose a high risk of contracting skin and soft tissue infections caused by Staphylococcus aureus. Those who are colonized with methicillin-resistant S. aureus (MRSA) that carry Panton-Valentine leukocidin (PVL) are predisposed to severe infections that could lead to necrotic skin infections. However the association of S. aureus specifically methicillin sensitive S. aureus carrying PVL gene in HIV patients has not been widely reported. Here, we study the prevalence and the molecular epidemiology of PVL-producing S...
August 2017: Malaysian Journal of Pathology
https://www.readbyqxmd.com/read/28862669/antimicrobial-susceptibility-of-staphylococcus-aureus-isolated-from-recreational-waters-and-beach-sand-in-eastern-cape-province-of-south-africa
#17
Olufemi Emmanuel Akanbi, Henry Akum Njom, Justine Fri, Anthony C Otigbu, Anna M Clarke
Background: Resistance of Staphylococcus aureus to commonly used antibiotics is linked to their ability to acquire and disseminate antimicrobial-resistant determinants in nature, and the marine environment may serve as a reservoir for antibiotic-resistant bacteria. This study determined the antibiotic sensitivity profile of S.aureus isolated from selected beach water and intertidal beach sand in the Eastern Cape Province of South Africa. Methods: Two hundred and forty-nine beach sand and water samples were obtained from 10 beaches from April 2015 to April 2016...
September 1, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28859499/prevalence-and-molecular-typing-of-methicillin-resistant-staphylococcus-aureus-carrying-panton-valentine-leukocidin-gene
#18
Maryam Rahimpour Hesari, Ali Salehzadeh, Reza Kazemi Darsanaki
Panton-Valentine leukocidin (pvl) toxin is an important virulence factor of Staphylococcus aureus. The main genes are coa and spa for distinguishing and typing of S. aureus isolates. The aim of this study was to investigate antibiotic resistance, presence of mecA and pvl genes, as well as epidemiological typing of these isolates according to polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method in clinical sample isolated from Rasht city, Iran. A total of 250 clinical samples have been isolated from different hospitals...
September 1, 2017: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/28857738/detection-of-high-levels-of-resistance-to-linezolid-and-vancomycin-in-staphylococcus-aureus
#19
Aysha Azhar, Samreen Rasool, Asma Haque, Sidra Shan, Muhammad Saeed, Beenish Ehsan, Abdul Haque
Both methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive S. aureus (MSSA) are rapidly overcoming the current array of drugs. One hundred and fifty isolates from a hospital were studied for resistance towards linezolid and vancomycin. Fifty-four (36.0 %) isolates were MRSA. Both MRSA and MSSA showed high resistance towards linezolid when using the disc diffusion method, with the figures being 48.1 and 29.2 %, respectively. The figures for the E-test were 46.3 and 27.0 %, respectively...
September 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28855819/antimicrobial-effect-of-different-types-of-honey-on-staphylococcus-aureus
#20
Saad B Almasaudi, Alaa A M Al-Nahari, El Sayed M Abd El-Ghany, Elie Barbour, Saad M Al Muhayawi, Soad Al-Jaouni, Esam Azhar, Mohamad Qari, Yousef A Qari, Steve Harakeh
Honey exhibits antimicrobial activities against a wide range of bacteria in different milieu. This study aims to compare the effects of five types of honey (both imported and local Saudi honey) against Staphylococcus aureus. The five types of honey (Manuka Honey UMF +20, Manuka Honey UMF +16, Active +10 Manuka Honey, Sidr honey and Nigella sativa honey) were evaluated for their bactericidal/bacteriostatic activities against both methicillin resistant and sensitive S. aureus. The inhibitory effect of honey on bacterial growth was evident at concentrations of 20% and 10% (v/v)...
September 2017: Saudi Journal of Biological Sciences
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