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urticarial vasculitis

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https://www.readbyqxmd.com/read/27921149/a-case-of-urticarial-vasculitis-in-a-female-patient-with-lupus-mycoplasma-pneumoniae-infection-or-lupus-reactivation
#1
Mario Diplomatico, Maria Francesca Gicchino, Orsola Ametrano, Pierluigi Marzuillo, Alma Nunzia Olivieri
A 17-year-old female patient affected by systemic lupus erythematosus (SLE) (who had been taking 300 mg/die of hydroxychloroquine for 3 years), Graves' disease (treated with 10 mg/die of tapazole), and celiac disease came to our attention for urticarial vasculitis. She had been taking prednisone (25 mg/die) for 3 days, and her blood tests showed high levels of Mycoplasma pneumoniae IgM and IgG antibodies. The association between urticaria and M. pneumoniae infections can be present in up to 7% of the cases and, to the best of our knowledge, only two reports of urticarial vasculitis and M...
December 5, 2016: Rheumatology International
https://www.readbyqxmd.com/read/27916573/purpuric-component-features-to-differentiate-urticarial-vasculitis-and-urticaria-without-vasculitis
#2
Belén Lozano Masdemont, Celia Horcajada Reales, Laura Gómez-Recuero Muñoz, Verónica Parra Blanco
No abstract text is available yet for this article.
December 1, 2016: Reumatología Clinica
https://www.readbyqxmd.com/read/27852431/urticarial-vasculitis-in-the-childhood-with-c2-hypocomplementenemia-a-rare-case
#3
Y Keyla Chan, R F J Criado, P R Criado, C D A S Machado, C Speyer
We report a first case of hypocomplementemic urticarial vasculitis of C2 fraction in a child, with cutaneous manifestation only, with no reports in scientific literature.
November 2016: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27821515/an-autosomal-recessive-dnase1l3-related-autoimmune-disease-with-unusual-clinical-presentation-mimicking-systemic-lupus-erythematosus
#4
A Carbonella, G Mancano, E Gremese, F S Alkuraya, N Patel, F Gurrieri, G Ferraccioli
We describe the third family in the world, after Arabian and Turkish ones, displaying an autosomal recessive autoimmune disease (AID), mimicking systemic lupus erythematosus (SLE), with unusual manifestations due to a homozygous frame-shift variant in DNASE1L3 SLE is a complex AID characterized by multiple organ involvement. Genetic risk variants identified account for only 15% of SLE heritability. Rare Mendelian forms have been reported, including DNASE1L3-related SLE.Through specific genetic tests we identified a homozygous 2 bp-deletion c...
November 7, 2016: Lupus
https://www.readbyqxmd.com/read/27818822/normocomplementaemic-urticarial-vasculitis-in-a-19-month-old-girl
#5
Peter Williams
Urticaria is common in children. Urticarial vasculitis (UV) is a potentially more serious, rare variant. The youngest reported case was 12 months of age. A systemically well, 19-month-old girl presented with her mother who was concerned about the development of a rash. On presentation, the child had normal vital signs, was alert, and was well and playing with toys. There was a widespread urticarial rash (raised, pruritic, and erythematous) that was most apparent on the trunk with minimal rash on the legs. Overlying this urticarial rash in a similar distribution was a blotchy, palpable purpuric rash and associated hyperpigmentation...
2016: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/27759482/dermatologic-uses-of-omalizumab
#6
Justin C Chia, P Régine Mydlarski
PURPOSE: Omalizumab is a recombinant humanized monoclonal antibody that inhibits the binding of immunoglobulin E (IgE) to the high-affinity IgE receptor (FceRI) on the surface of mast cells and basophils. Omalizumab has been approved for use in asthma, and new reports show promise in a variety of dermatologic diseases. Herein, we review the literature on omalizumab in dermatology and discuss the safety, efficacy and mechanisms of action for this emerging therapy. MATERIALS AND METHODS: PubMED, MEDLINE and Embase databases were searched for the period 1 January 1990 to 1 September 2016...
November 7, 2016: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/27580419/leukocytoclastic-vasculitis-in-children-clinical-characteristics-subtypes-causes-and-direct-immunofluorescence-findings-of-56-biopsy-confirmed-cases
#7
E F Johnson, D A Wetter, J S Lehman, J L Hand, D M R Davis, M M Tollefson
BACKGROUND: Leukocytoclastic vasculitis (LCV) in children is a complex group of conditions. OBJECTIVES: This study presents the demographics, clinical features, direct immunofluorescence (DIF) results and suspected aetiologies of 56 biopsy-confirmed cases of leukocytoclastic vasculitis in children. METHODS: Retrospective review of 56 children seen at Mayo Clinic in Rochester, Minnesota, from 1993 to 2013 with clinical features and cutaneous biopsy consistent with LCV...
August 31, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27190661/urticarial-vasculitis-associated-intestinal-ischemia
#8
Uni Wong, Harris Yfantis, Guofeng Xie
Urticarial vasculitis (UV) is a rare small vessel vasculitis. UV is often idiopathic but can also present in the context of autoimmune disorders such as systemic lupus erythematosus, drug reactions, infections, or a paraneoplastic syndrome. Extracutaneous complications include intestinal ischemic injuries, in UV patients with nonspecific gastrointestinal symptoms such as abdominal pain and nausea. Prompt recognition and treatment can minimize morbidity and mortality. This paper describes a case of urticarial vasculitis-associated intestinal ischemia...
2016: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/27118389/management-of-small-vessel-vasculitides
#9
REVIEW
Giuseppe Lopalco, Donato Rigante, Vincenzo Venerito, Giacomo Emmi, Maria Grazia Anelli, Giovanni Lapadula, Florenzo Iannone, Luca Cantarini
Inflammation mediated by cells of the immune system and necrosis are the most striking features observed at the histologic level in patients with vasculitides, clinical entities classified according to pathologic findings involving different organs, to etiology, or to size of vessels involved. Small vessel vasculitides (SVV) are a peculiar group of systemic disorders electively involving small intraparenchymal arteries, arterioles, capillaries, or venules and leading to different levels of vascular obstruction, tissue ischemia and risk of infarction; they can be divided into anti-neutrophil cytoplasmic antibody-associated vasculitides and immune complex vasculitides...
June 2016: Current Rheumatology Reports
https://www.readbyqxmd.com/read/26985173/clinical-characteristics-of-cutaneous-lupus-erythematosus
#10
Justyna Szczęch, Maja Rutka, Dominik Samotij, Agnieszka Zalewska, Adam Reich
INTRODUCTION: Lupus erythematosus (LE) shows a wide variety of clinical manifestations, skin involvement being one of the most important. AIM: To analyze the clinical presentation of cutaneous variants of lupus erythematosus in terms of skin lesion spectrum and extracutaneous involvement. MATERIAL AND METHODS: A total of 64 patients with cutaneous LE (CLE) were included. The study was based on the "Core Set Questionnaire" developed by the European Society of Cutaneous Lupus Erythematosus (EUSCLE)...
February 2016: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/26882797/-vasculitides-in-childhood-a-retrospective-study-in-a-period-from-2002-to-2012-at-the-department-of-paediatrics-university-hospital-centre-zagreb
#11
Marija Jelusić, Lucija Kostić, Marijan Frković, Masa Davidović, Ivan Malcić
The aim of our study was to analyze clinical features, laboratory findings, treatment, course and outcome of different types of vasculitis in children. All children aged up to 18 years that have been diagnosed with a vasculitis disorder from 2002. to 2012. at the Department of Paediatric, University Hospital Centre Zagreb according to EULAR/PRES/PRINTO criteria were included in the study. Vasculitis was diagnosed in 180 children, 101 girls and 79 boys, mean age 7.19 ± 3.7 years, with an average follow-up of 5...
2015: Reumatizam
https://www.readbyqxmd.com/read/26825166/neutrophilic-dermatosis-limited-to-lipo-lymphedematous-skin-in-a-morbidly-obese-woman-on-dasatinib-therapy
#12
Sanaz Ainechi, John Andrew Carlson
Neutrophilic dermatosis (ND) confined to postmastectomy lymphedema, localized Sweet syndrome, is a newly recognized disease. In this study, the authors describe a 44-year-old obese woman with chronic myelogenous leukemia in molecular remission on dasatinib therapy, who presented with a painful urticarial eruption limited to lipo-lymphedematous skin and accompanied by malaise, episodic fever, diarrhea, neutrophilia, and leukocytosis. Initially transient and migratory, the rash became fixed, papular, and vesicular and showed minimal response to corticosteroids...
February 2016: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/26600649/telmisartan-induced-urticarial-vasculitis
#13
Vikram K Mahajan, Ravinder Singh, Mrinal Gupta, Rashmi Raina
A 53-year-old man developed urticarial vasculitis following ingestion of telmisartan and hydrochlorothiazide combination for hypertension. Treatment with prednisolone and cetirizine was curative, but his lesions recurred when he continued telmisartan and hydrochlorothiazide against medical advice. Re-challenge with the same doses of telmisartan precipitated similar lesions with telmisartan and not with hydrochlorothiazide. This uncommon cutaneous adverse reaction of angiotensin II receptor blockers has implication for the clinicians as more such cases may become apparent with their wider use than in premarketing studies...
September 2015: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/26545308/comorbidity-and-pathogenic-links-of-chronic-spontaneous-urticaria-and-systemic-lupus-erythematosus-a-systematic-review
#14
REVIEW
P Kolkhir, D Pogorelov, O Olisova, M Maurer
Chronic spontaneous urticaria (CSU) is a common mast cell-driven disease characterized by the development of wheals (hives), angioedema (AE), or both for > 6 weeks. It is thought that autoimmunity is a common cause of CSU, which is often associated with autoimmune thyroiditis, whereas the link to other autoimmune disorders such as systemic lupus erythematosus (SLE) has not been carefully explored. Here, we systematically reviewed the existing literature for information on the prevalence of CSU in SLE (and vice versa) and we examined the possible clinical and pathogenetic relationship between CSU and SLE...
February 2016: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/26435858/omalizumab-for-urticarial-vasculitis-case-report-and-review-of-the-literature
#15
Misbah Nasheela Ghazanfar, Simon Francis Thomsen
Urticarial vasculitis is characterised by inflamed itching or burning red patches or wheals that resemble urticaria but persist for greater than 24 hours. It is often idiopathic but is sometimes associated with collagen-vascular disease, particularly systemic lupus erythematosus. Treatment options include oral antihistamines, oral corticosteroids, dapsone, colchicine or hydroxychloroquine. We describe a male patient with urticarial vasculitis who was treated with omalizumab (anti-IgE) with convincing results and provide a review of previous reports of patients with urticarial vasculitis treated with omalizumab...
2015: Case Reports in Dermatological Medicine
https://www.readbyqxmd.com/read/26425571/urticarial-vasculitis-in-a-teenage-girl
#16
Aaron McGuffin, Amy Vaughan, Juliet Wolford
This case involves a 13-year-old female who presented to the pediatrician for a routine check-up with complaints of a long history of intermittent diarrhea followed by a severe rash lasting for up to a week afterwards. The mother had described her daughter's condition to multiple physicians, several whom had seen her during flare-ups. The nonmigratory lesions resembled "hives" with a single lesion lasting for 48 to 72 hours and resolving into what her parent described as a bruise. They often diagnosed her daughter with urticaria and prescribed steroids, which did resolve the acute flare-ups...
April 2013: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/26412031/posterior-reversible-encephalopathy-syndrome-and-systemic-vasculitis-report-of-six-cases
#17
Bertrand Lioger, Elisabeth Diot, Michael Ebbo, Nicolas Schleinitz, Laurent Aaron, Jean-Marie Michot, Olivier Lambotte, Robin Dhote, Hubert De Boysson, Elodie Ponce, François Maillot
OBJECTIVES: Our objective was to describe the characteristics of posterior reversible encephalopathy syndrome (PRES) associated with systemic vasculitis. METHODS: A standardised questionnaire was used for a nationwide retrospective multicentre study in 2013 to collect clinical, radiological and outcome data about PRES associated with systemic vasculitis. RESULTS: We included six patients (all women; mean age 22.6±19.8 years (20-62)): two with polyarteritis nodosa and one case of each granulomatosis with polyangiitis, cryoglobulinaemic vasculitis, hypocomplementemic urticarial vasculitis, and Takayasu arteritis...
May 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/26372544/-the-situation-regarding-hypocomplementemic-urticarial-vasculitis-in-2015
#18
EDITORIAL
B Flageul
No abstract text is available yet for this article.
October 2015: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/26276260/hypocomplementemic-urticarial-vasculitis-arising-in-a-patient-with-immunoglobulin-g4-related-disease
#19
Mariko Takao, Toshihisa Hamada, Tatsuya Kaji, Kazuko Ikeda-Mizuno, Chinatsu Takehara-Yasuhara, Kouichi Ichimura, Hiroyuki Yanai, Tadashi Yshino, Keiji Iwatsuki
BACKGROUND: Hypocomplementemic urticarial vasculitis (HUV) has been defined as a syndrome associated with urticarial lesions caused by leukocytoclastic vasculitis. It has been observed in patients with systemic lupus erythematosus and related conditions. Immunoglobulin G4 (IgG4)-related disease is a lymphoproliferative disorder characterized by sclerosing pancreatitis, retroperitoneal fibrosis, sclerotic cholangitis, acute interstitial nephritis, and Mikulicz's disease, and associated with elevated levels of IgG4 and hypocomplementemia...
April 2016: International Journal of Dermatology
https://www.readbyqxmd.com/read/26225328/correlation-of-serum-antithyroid-microsomal-antibody-and-autologous-serum-skin-test-in-patients-with-chronic-idiopathic-urticaria
#20
Snehal Balvant Lunge, Milind Borkar, Sushil Pande
BACKGROUND: About 25-45% of patients of chronic urticaria (CU) have been stated to have histamine releasing autoantibodies in their blood. The term autoimmune urticaria is increasingly being accepted for this subgroup of patients. Review of the literature suggests high autologous serum skin test (ASST) positivity and presence of antithyroid microsomal antibodies in patients with autoimmune urticaria. AIMS: To study prevalence of ASST positivity and antithyroid microsomal antibodies in chronic "idiopathic" urticaria and to study the correlation between the two parameters...
July 2015: Indian Dermatology Online Journal
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