Y Kotovskaya, S Villevalde, M Efremovtseva, Z Kobalava
OBJECTIVE: The loss of physiological stiffness mismatch between aorta and peripheral arteries was strongly and independently associated with increased mortality in adult dialysis population. The aim of the study was to evaluate if the reversal of arterial stiffness mismatch was present in pre-dialysis patients with chronic kidney disease (CKD). DESIGN AND METHOD: The aortic-brachial arterial stiffness mismatch (pulse wave velocity (PWV ratio) were assessed using carotid-femoral PWV divided by carotid-radial PWV in 112 adult treated hypertensive CKD patients: 54 - with CKD IIIa (age 59,5 ± 8,4 years, male 46,3%, brachial blood pressure (BP) 149,6 ± 10,3/85,8 ± 9,8 mmHg), 35 - with CKD IIIb (age 60,2 ± 7,8 years, male 45,7%, BP 152,5 ± 12,5/86,4 ± 10,2 mmHg) and 23 with CKD IV (age 57,3 ± 10,2, male 43,4%, BP 156,1 ± 14,3/92,8 ± 12,4 mmHg)...
June 2015: Journal of Hypertension