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chronic renal desease

T E Nichik, N S Lin'kova, N A Kraskovskaia, A V Dudkov, V Kh Khavinson
The review considers molecular mechanisms of chronic renal failure and cancer kidney disease. The most important molecules inducing inflammation are cytokines (MCP-1, TNFalpha, IFN-gamma, IL-1,6,8,18), matrix metalloproteinases MMP-2,3,9,14, tissue inhibitors of metalloproteinases (TIMPs) and grow factors (VEGF PDGE FGF). This signal molecules regulate the activity of immune cells and remodeling extracellular matrix (ECM) components taken place in inflammatory reactions, proliferation, apoptosis and also in the differentiation of kidney cells...
April 2014: Uspekhi Fiziologicheskikh Nauk
Tamara Dragović
INTRODUCTION: Hypothyroidism is often accompanied with decline of kidney function, or inability to maintain electrolyte balance. These changes are usually overlooked in everyday practice. Early recognition of this association eliminates unnecessary diagnostic procedures that postpone the adequate treatment. CASE REPORT: Two patients with elevated serum creatinine levels due to primary autoimmune hypothyroidism, with complete recovery of creatinine clearance after thyroid hormone substitution therapy are presented...
February 2012: Vojnosanitetski Pregled. Military-medical and Pharmaceutical Review
Hao Liu, Hong Shi, Jinming Yu, Fang Chen, Qingwu Jiang, Dayi Hu
AIM: Chronic kidney disease (CKD) is an important risk factor for cardiovascular disease (CVD) events. A high ankle brachial index (ABI), a marker of lower arterial stiffness, is associated with CVD events. It remains unknown whether high ABI is associated with CKD. The objectives of this study were to determine the association of CKD with high ABI in adults at high CVD risk. METHODS: The study enrolled hospital-based patients at high CVD risk and measured kidney function and ABI...
2011: Journal of Atherosclerosis and Thrombosis
Zai-Kang Zhang, Guo-Xing Deng, Yu-Guang Zheng, Rui-Xue Feng, Qiu-Ying Zhang, Zhi-Qiang Chen
We reviewed the modern development of clinical application and experimental reseach on the prescription Biejiajian Wan (BJ), which are the basement that we will study its anti-renal fibrosis. At present, the prescription BJ is mainly applied to the treatment of chronic heptic desease. Its experimental reseach is mainly confined to the studing of anti-heptic fibrosi. Refering the scientific and technological result of anti-heptic fibrosis, we think the prescription BJ would have the effection of anti-renal fibrosis on the basis of theory of planning treatment according to diagnosis...
April 2008: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
Natasa Jovanović, Mirjana Lausević, Vidosava Nesić, Gordana Grujić-Adanja, Biljana Stojimirović
INTRODUCTION: Normocytic, normochromic anemia is one of the first signs of chronic renal failure and it is common in patients on chronic dialysis treatment. It causes decrease in oxygen supply to tissues, increases cardiac minute volume, causes left ventricular hyperthrophy, cardiac insufficiency, disorders related to cognitive functions and immune response, and increases morbidity and mortality rates. The leading cause of anemia in patients on chronic peritoneal dialysis (PD) is iron depletion and most patients on PD need oral or parenteral iron supplementation...
January 2005: Medicinski Pregled
T Fujita, K Ando, H Nishimura, T Ideura, G Yasuda, M Isshiki, K Takahashi
Cilnidipine, a dual L-/N-type calcium channel blocker, dilates both efferent and afferent arterioles and is renoprotective. Our multi-center, open-labeled, and randomized trial compared the antiproteinuric effect of cilnidipine with that of amlodipine in hypertensive patients with kidney disease. A group of 339 patients, already receiving renin-angiotensin system inhibitor treatment, were randomly assigned to cilnidipine or amlodipine. The primary endpoint was a decrease in the urinary protein to creatinine ratio...
December 2007: Kidney International
G Novelli, M Rossi, F Pugliese, I Poli, E Ruberto, S Martelli, F Nudo, V Morabito, G Mennini, P B Berloco
BACKGROUND: The aim of our study was to show an improvement in Model for End-Stage Liver Disease (MELD) score after treatment with Molecular adsorbents recirculating system (MARS) in acute-on-chronic hepatitis (AoCHF) patients. MELD was adopted to determine the prognosis of patients with liver chronic desease. We evaluated the possibility to improve the MELD score of patients awaiting liver transplantation using a liver support device, namely, MARS. PATIENTS AND METHODS: From September 1999 to April 2006, we treated 80 patients whose diagnoses were hepatitis C, 41...
July 2007: Transplantation Proceedings
W Höfer, R Baethke
No abstract text is available yet for this article.
September 1971: Der Internist
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