Cuong Chi Ngo, Shungo Katoh, Futoshi Hasebe, Bhim Gopal Dhoubhadel, Tomoko Hiraoka, Sugihiro Hamaguchi, Anh Thi Kim Le, Anh Thi Hien Nguyen, Anh Duc Dang, Chris Smith, Lay-Myint Yoshida, Cuong Duy Do, Thuy Thi Thanh Pham, Koya Ariyoshi
BACKGROUND: Laboratory facilities for etiological diagnosis of central nervous system (CNS) infection are limited in developing countries; therefore, patients are treated empirically, and the epidemiology of the pathogens is not well-known. Tubercular meningitis is one of the common causes of meningitis, which has high morbidity and mortality, but lacks sensitive diagnostic assays. The objectives of this study were to determine the causes of meningitis in adult patients by using molecular assays, to assess the risk factors associated with them, and to explore whether biomarkers can differentiate tubercular meningitis from bacterial meningitis...
May 21, 2021: Tropical Medicine and Health