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T2-mapping

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https://www.readbyqxmd.com/read/29762089/juvenile-osteochondritis-dissecans-cartilage-t2-mapping-of-stable-medial-femoral-condyle-lesions
#1
Jie C Nguyen, Fang Liu, Donna G Blankenbaker, Kaitlin M Woo, Richard Kijowski
Purpose To determine whether a T2 mapping sequence could depict early changes in the composition and microstructure of cartilage overlying stable lesions of the medial femoral condyle in patients with juvenile osteochondritis dissecans (JOCD). Materials and Methods This retrospective study analyzed a sagittal T2 mapping sequence performed between September 1, 2015, and March 31, 2017, on 16 patients (10 boys and six girls; median age, 11.5 years) with 18 stable medial femoral condyle JOCD lesions and 18 age-, sex-, and skeletal maturation-matched control participants (11 boys and seven girls; median age, 11...
May 15, 2018: Radiology
https://www.readbyqxmd.com/read/29748200/extent-of-microstructural-tissue-damage-correlates-with-hemodynamic-failure-in-high-grade-carotid-occlusive-disease-an-mri-study-using-quantitative-t2-and-dsc-perfusion
#2
A Seiler, R Deichmann, U Nöth, A Lauer, W Pfeilschifter, O C Singer, M Wagner
BACKGROUND AND PURPOSE: Chronic hemodynamic impairment in high-grade carotid occlusive disease is thought to cause microstructural abnormalities that might be subclinical or lead to subtle symptoms including cognitive impairment. Quantitative MR imaging allows assessing pathologic structural changes beyond macroscopically visible tissue damage. In this study, high-resolution quantitative T2 mapping combined with DSC-based PWI was used to investigate quantitative T2 changes as a potential marker of microstructural damage in relation to hemodynamic impairment in patients with unilateral high-grade carotid occlusive disease...
May 10, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29744935/fast-magnetic-resonance-fingerprinting-for-dynamic-contrast-enhanced-studies-in-mice
#3
Yuning Gu, Charlie Y Wang, Christian E Anderson, Yuchi Liu, He Hu, Mette L Johansen, Dan Ma, Yun Jiang, Ciro Ramos-Estebanez, Susann Brady-Kalnay, Mark A Griswold, Chris A Flask, Xin Yu
PURPOSE: The goal of this study was to develop a fast MR fingerprinting (MRF) method for simultaneous T1 and T2 mapping in DCE-MRI studies in mice. METHODS: The MRF sequences based on balanced SSFP and fast imaging with steady-state precession were implemented and evaluated on a 7T preclinical scanner. The readout used a zeroth-moment-compensated variable-density spiral trajectory that fully sampled the entire k-space and the inner 10 × 10 k-space with 48 and 4 interleaves, respectively...
May 9, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29734489/diagnostic-performance-of-intravoxel-incoherent-motion-diffusion-weighted-imaging-in-the-assessment-of-the-dynamic-status-of-myocardial-perfusion
#4
Dong-Aolei An, Bing-Hua Chen, Rui-Wu, Ruo-Yang Shi, Jun Bu, Heng Ge, Jiani Hu, Jian-Rong Xu, Lian-Ming Wu
BACKGROUND: Acute myocardial infarction (AMI) is a major cause of morbidity and mortality worldwide and places a significant financial burden on our society. PURPOSE: To determine the feasibility of cardiac intravoxel incoherent motion (IVIM) in the consecutive evaluation of myocardial perfusion in myocardial infarction patients postpercutaneous coronary intervention (PCI) and to investigate the dynamic biological phenomena in myocardial perfusion after AMI. STUDY TYPE: Prospective observational study...
May 7, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29733917/clinical-equivalence-assessment-of-t2-synthesized-pediatric-brain-magnetic-resonance-imaging
#5
Basile Kerleroux, Tobias Kober, Tom Hilbert, Maxence Serru, Dominique Sirinelli, Baptiste Morel
BACKGROUND AND PURPOSE: Automated synthetic magnetic resonance imaging (MRI) provides qualitative, weighted image contrasts as well as quantitative information from one scan and is well-suited for various applications such as analysis of white matter disorders. However, the synthesized contrasts have been poorly evaluated in pediatric applications. The purpose of this study was to compare the image quality of synthetic T2 to conventional turbo spin echo (TSE) T2 in pediatric brain MRI...
May 4, 2018: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/29731420/performance-of-t2-maps-in-the-detection-of-prostate-cancer
#6
Aritrick Chatterjee, Ajit Devaraj, Melvy Mathew, Teodora Szasz, Tatjana Antic, Gregory S Karczmar, Aytekin Oto
RATIONALE AND OBJECTIVES: This study compares the performance of T2 maps in the detection of prostate cancer (PCa) in comparison to T2-weighted (T2W) magnetic resonance images. MATERIALS AND METHODS: The prospective study was institutional review board approved. Consenting patients (n = 45) with histologic confirmed PCa underwent preoperative 3-T magnetic resonance imaging with or without endorectal coil. Two radiologists, working independently, marked regions of interests (ROIs) on PCa lesions separately on T2W images and T2 maps...
May 3, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29730991/feasibility-of-cardiovascular-magnetic-resonance-to-detect-oxygenation-deficits-in-patients-with-multi-vessel-coronary-artery-disease-triggered-by-breathing-maneuvers
#7
Kady Fischer, Kyohei Yamaji, Silvia Luescher, Yasushi Ueki, Bernd Jung, Hendrik von Tengg-Kobligk, Stephan Windecker, Matthias G Friedrich, Balthasar Eberle, Dominik P Guensch
BACKGROUND: Hyperventilation with a subsequent breath-hold has been successfully used as a non-pharmacological vasoactive stimulus to induce changes in myocardial oxygenation. The purpose of this pilot study was to assess if this maneuver is feasible in patients with multi-vessel coronary artery disease (CAD), and if it is effective at detecting coronary artery stenosis > 50% determined by quantitative coronary angiography (QCA). METHODS: Twenty-six patients with coronary artery stenosis (QCA > 50% diameter stenosis) underwent a contrast-free cardiovascular magnetic resonance (CMR) exam in the time interval between their primary coronary angiography and a subsequent percutaneous coronary intervention (PCI, n = 24) or coronary artery bypass (CABG, n = 2) revascularization procedure...
May 7, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29717788/assessment-of-liver-ischemia-reperfusion-injury-in-mice-using-hepatic-t-2-mapping-comparison-with-histopathology
#8
Katja Hueper, Hannah Lang, Björn Hartleben, Marcel Gutberlet, Thorsten Derlin, Tobias Getzin, Rongjun Chen, Hassan Abou-Rebyeh, Frank Lehner, Martin Meier, Hermann Haller, Frank Wacker, Song Rong, Faikah Gueler
BACKGROUND: Liver ischemia reperfusion injury (IRI) occurs during liver surgery or transplantation resulting in an inflammatory response, tissue damage, and functional impairment of the organ. PURPOSE: To assess the feasibility of T2 mapping for noninvasive quantification of liver edema after partial liver IRI in mice. STUDY TYPE: Prospective, experimental study. ANIMAL MODEL: Partial liver IRI was induced in C57BL/6-mice by transient clamping of the left lateral and median liver lobes for 35 (n = 8), 45 (n = 6), 60 (n = 17), or 90 minutes (n = 5)...
May 2, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29713414/evaluation-of-lumbar-intervertebral-disc-degeneration-using-t1%C3%AF-and-t2-magnetic-resonance-imaging-in-a-rabbit-disc-injury-model
#9
Tetsuhiro Ishikawa, Atsuya Watanabe, Hiroto Kamoda, Masayuki Miyagi, Gen Inoue, Kazuhisa Takahashi, Seiji Ohtori
Study Design: An in vivo histologic and magnetic resonance imaging (MRI) study of lumbar intervertebral disc (IVD) degeneration was conducted. Purpose: To clarify the sensitivity and efficacy of T1ρ/T2 mapping for IVD degeneration, the correlation between T1ρ/T2 mapping and degenerative grades and histological findings in the lumbar IVD were investigated. Overview of Literature: The early signs of IVD degeneration are proteoglycan loss, dehydration, and collagen degradation...
April 2018: Asian Spine Journal
https://www.readbyqxmd.com/read/29708212/myocardial-tissue-characterization-by-combining-late-gadolinium-enhancement-imaging-and-percent-edema-mapping-a-novel-t2-map-based-mri-method-in-canine-myocardial-infarction
#10
Pal Suranyi, Gabriel A Elgavish, U Joseph Schoepf, Balazs Ruzsics, Pal Kiss, Marly van Assen, Brian E Jacobs, Brigitta C Brott, Ada Elgavish, Akos Varga-Szemes
Background: Assessing the extent of ischemic and reperfusion-associated myocardial injuries remains challenging with current magnetic resonance imaging (MRI) techniques. Our aim was to develop a tissue characterization mapping (TCM) technique by combining late gadolinium enhancement (LGE) with our novel percent edema mapping (PEM) approach to enable the classification of tissue represented by MRI voxels as healthy, myocardial edema (ME), necrosis, myocardial hemorrhage (MH), or scar. Methods: Six dogs underwent closed-chest myocardial infarct (MI) generation...
2018: European radiology experimental
https://www.readbyqxmd.com/read/29704036/evaluation-of-articular-cartilage-following-rotational-acetabular-osteotomy-for-hip-dysplasia-using-t2-mapping-mri
#11
Takeshi Shoji, Takuma Yamasaki, Soutaro Izumi, Mikiya Sawa, Yuji Akiyama, Yuji Yasunaga, Nobuo Adachi
BACKGROUND: Rotational acetabular osteotomy (RAO) is one of the surgical treatments for acetabular dysplasia, and satisfactory results have been reported. We evaluated the postoperative changes of articular cartilage and whether the pre-operative condition of the articular cartilage influences the clinical results using T2 mapping MRI. METHODS: We reviewed 31 hips with early stage osteoarthritis in 31 patients (mean age, 39.6 years), including three men and 28 women who underwent RAO for hip dysplasia...
April 27, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29703978/time-efficient-whole-brain-coverage-with-mr-fingerprinting-using-slice-interleaved-echo-planar-imaging
#12
Benedikt Rieger, Mehmet Akçakaya, José C Pariente, Sara Llufriu, Eloy Martinez-Heras, Sebastian Weingärtner, Lothar R Schad
Magnetic resonance fingerprinting (MRF) is a promising method for fast simultaneous quantification of multiple tissue parameters. The objective of this study is to improve the coverage of MRF based on echo-planar imaging (MRF-EPI) by using a slice-interleaved acquisition scheme. For this, the MRF-EPI is modified to acquire several slices in a randomized interleaved manner, increasing the effective repetition time of the spoiled gradient echo readout acquisition in each slice. Per-slice matching of the signal-trace to a precomputed dictionary allows the generation of T1 and T2 * maps with integrated B1 + correction...
April 27, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29700795/changes-in-the-adc-of-diffusion-weighted-mri-with-the-oscillating-gradient-spin-echo-ogse-sequence-due-to-differences-in-substrate-viscosities
#13
Tomoko Maekawa, Masaaki Hori, Katsutoshi Murata, Thorsten Feiweier, Issei Fukunaga, Christina Andica, Akifumi Hagiwara, Koji Kamagata, Saori Koshino, Osamu Abe, Shigeki Aoki
PURPOSE: Compared with the conventional pulsed gradient spin-echo (PGSE) sequence, diffusion-weighted imaging (DWI) with the oscillating gradient spin-echo (OGSE) sequence can shorten the diffusion time by changing the frequency. The purpose was to investigate whether n-alkanes are suitable as isotropic phantoms for estimating the diffusion coefficient with the OGSE sequence. MATERIALS AND METHODS: We investigated changes in the apparent diffusion coefficient (ADC) due to differences in the viscosities of nine n-alkane phantoms with different numbers of carbon atoms from C8 H18 to C16 H34 using OGSE and PGSE sequences at 21 °C...
April 26, 2018: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/29687923/quantitative-susceptibility-mapping-of-articular-cartilage-ex-vivo-findings-at-multiple-orientations-and-following-different-degradation-treatments
#14
Olli Nykänen, Lassi Rieppo, Juha Töyräs, Ville Kolehmainen, Simo Saarakkala, Karin Shmueli, Mikko J Nissi
PURPOSE: We investigated the feasibility of quantitative susceptibility mapping (QSM) for assessing degradation of articular cartilage by measuring ex vivo bovine cartilage samples subjected to different degradative treatments. Specimens were scanned at several orientations to study if degradation affects the susceptibility anisotropy. T2*-mapping, histological stainings, and polarized light microscopy were used as reference methods. Additionally, simulations of susceptibility in layered geometry were performed...
April 24, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29687915/single-shot-t-2-mapping-using-overlapping-echo-detachment-planar-imaging-and-a-deep-convolutional-neural-network
#15
Congbo Cai, Chao Wang, Yiqing Zeng, Shuhui Cai, Dong Liang, Yawen Wu, Zhong Chen, Xinghao Ding, Jianhui Zhong
PURPOSE: An end-to-end deep convolutional neural network (CNN) based on deep residual network (ResNet) was proposed to efficiently reconstruct reliable T2 mapping from single-shot overlapping-echo detachment (OLED) planar imaging. METHODS: The training dataset was obtained from simulations that were carried out on SPROM (Simulation with PRoduct Operator Matrix) software developed by our group. The relationship between the original OLED image containing two echo signals and the corresponding T2 mapping was learned by ResNet training...
April 24, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29681243/association-between-myocardial-extracellular-volume-and-strain-analysis-through-cardiovascular-magnetic-resonance-with-histological-myocardial-fibrosis-in-patients-awaiting-heart-transplantation
#16
Yue Cui, Yukun Cao, Jing Song, Nianguo Dong, Xiangchuang Kong, Jing Wang, Yating Yuan, Xiaolei Zhu, Xu Yan, Andreas Greiser, Heshui Shi, Ping Han
BACKGROUND: Cardiovascular magnetic resonance (CMR)-derived extracellular volume (ECV) and tissue tracking strain analyses are proposed as non-invasive methods for quantifying myocardial fibrosis and deformation. This study sought (1) to histologically validate myocardial ECV against the collagen volume fraction (CVF) measured from tissue samples of patients undergoing heart transplantation and (2) to detect the correlations between myocardial systolic strain and the myocardial ECV and histological CVF in patients undergoing heart transplantation...
April 23, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29679101/t2-mapping-of-the-sacroiliac-joints-at-1-5-tesla-a-feasibility-and-reproducibility-study
#17
Domenico Albano, Vito Chianca, Renato Cuocolo, Rodolfo Bignone, Francesco Ciccia, Luca Maria Sconfienza, Massimo Midiri, Arturo Brunetti, Roberto Lagalla, Massimo Galia
OBJECTIVE: To evaluate the reproducibility of T2 relaxation time measurements of the sacroiliac joints at 1.5 T. MATERIALS AND METHODS: Healthy volunteers underwent an oblique axial multislice multiecho spin-echo sequence of the sacroiliac joints at 1.5 T. Regions of interest were manually drawn using a dedicated software by two musculoskeletal radiologists to include the cartilaginous part of the sacroiliac joints. A senior radiologist performed the measurement twice, while a resident measured once...
April 20, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29673122/native-myocardial-t1-time-can-predict-development-of-subsequent-anthracycline-induced-cardiomyopathy
#18
Fabian Muehlberg, Stephanie Funk, Leonora Zange, Florian von Knobelsdorff-Brenkenhoff, Edyta Blaszczyk, Alexander Schulz, Saeed Ghani, Annete Reichardt, Peter Reichardt, Jeanette Schulz-Menger
AIMS: This study aims to assess subclinical changes in functional and morphological myocardial magnetic resonance parameters very early into an anthracycline treatment, which may predict subsequent development of anthracycline-induced cardiomyopathy (aCMP). METHODS AND RESULTS: Thirty sarcoma patients with planned anthracycline-based chemotherapy (360-400 mg/m2 doxorubicin-equivalent) were recruited. Median treatment time was 19.1 ± 2.1 weeks. Enrolled individuals received three cardiovascular magnetic resonance studies (before treatment, 48 h after first anthracycline treatment, and upon completion of treatment)...
April 19, 2018: ESC Heart Failure
https://www.readbyqxmd.com/read/29666996/comparison-of-t2-relaxation-values-in-subtalar-cartilage-between-patients-with-lateral-instability-of-the-ankle-joint-and-healthy-volunteers
#19
Hyun Su Kim, Young Cheol Yoon, Ki Sun Sung, Min-Ji Kim, Soohyun Ahn
PURPOSE: To evaluate the difference between T2 relaxation values of the subtalar cartilage in lateral ankle instability patients and healthy volunteers. MATERIALS AND METHODS: This institutional review board-approved study included 27 preoperative magnetic resonance imaging (MRI) examinations of 26 patients who underwent Broström operations. Data of previously enrolled healthy volunteers (12 volunteers, 13 MRIs) were used as controls. Two radiologists independently measured T2 values in eight posterior subtalar joint cartilage compartments: central calcaneus anterior (CCA) and posterior (CCP), central talus anterior (CTA) and posterior (CTP), lateral calcaneus anterior (LCA) and posterior (LCP), and lateral talus anterior (LTA) and posterior (LTP)...
April 17, 2018: European Radiology
https://www.readbyqxmd.com/read/29666564/neural-induction-potential-and-mri-of-adscs-labeled-cationic-superparamagnetic-iron-oxide-nanoparticle-in-vitro
#20
Weiqiong Ma, Qi Xie, Baolin Zhang, Huixian Chen, Jianyi Tang, Zhengxian Lei, Minyi Wu, Dingxuan Zhang, Jiani Hu
Magnetic resonance imaging (MRI) combined with contrast agents is believed to be useful for stem cell tracking in vivo, and the aim of this research was to investigate the biosafety and neural induction of SD rat-originated adipose derived stem cells (ADSCs) using cationic superparamagnetic iron oxide (SPIO) nanoparticle which was synthesized by the improved polyol method, in order to allow visualization using in vitro MRI. The scan protocols were performed with T2-mapping sequence; meanwhile, the ultrastructure of labeled cells was observed by transmission electron microscopy (TEM) while the iron content was measured by inductively coupled plasma-atomic emission spectrometry (ICP-AES)...
2018: Contrast Media & Molecular Imaging
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