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T2-mapping

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https://www.readbyqxmd.com/read/27904982/magnetic-resonance-evaluation-of-cardiac-thrombi-and-masses-by-t1-and-t2-mapping-an-observational-study
#1
Thibault Caspar, Soraya El Ghannudi, Mickaël Ohana, Aïssam Labani, Aubrietia Lawson, Patrick Ohlmann, Olivier Morel, Michel De Mathelin, Catherine Roy, Afshin Gangi, Philippe Germain
The purpose of this work was to evaluate CMR T1 and T2 mapping sequences in patients with intracardiac thrombi and masses in order to assess T1 and T2 relaxometry usefulness and to allow better etiological diagnosis. This observational study of patients scheduled for routine CMR was performed from September 2014 to August 2015. All patients referred to our department for a 1.5 T CMR were screened to participate. T1 mapping were acquired before and after Gadolinium injection; T2 mapping images were obtained before injection...
December 1, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27896400/quantitative-assessment-of-the-supraspinatus-tendon-on-mri-using-t2-t2-mapping-and-shear-wave-ultrasound-elastography-a-pilot-study
#2
Konstantin Krepkin, Mary Bruno, José G Raya, Ronald S Adler, Soterios Gyftopoulos
OBJECTIVE: To determine whether there is an association between T2/T2* mapping and supraspinatus tendon mechanical properties as assessed by shear-wave ultrasound elastography (SWE). MATERIALS AND METHODS: This HIPAA-compliant prospective pilot study received approval from our hospital's institutional review board. Eight patients (3 males/5 females; age range 44-72 years) and nine shoulders underwent conventional shoulder MRI, T2/T2* mapping on a 3-T scanner, and SWE...
November 28, 2016: Skeletal Radiology
https://www.readbyqxmd.com/read/27894068/residual-myocardial-iron-following-intramyocardial-hemorrhage-during-the-convalescent-phase-of-reperfused-st-segment-elevation-myocardial-infarction-and-adverse-left-ventricular-remodeling
#3
Heerajnarain Bulluck, Stefania Rosmini, Amna Abdel-Gadir, Steven K White, Anish N Bhuva, Thomas A Treibel, Marianna Fontana, Manish Ramlall, Ashraf Hamarneh, Alex Sirker, Anna S Herrey, Charlotte Manisty, Derek M Yellon, Peter Kellman, James C Moon, Derek J Hausenloy
BACKGROUND: The presence of intramyocardial hemorrhage (IMH) in ST-segment-elevation myocardial infarction patients reperfused by primary percutaneous coronary intervention has been associated with residual myocardial iron at follow-up, and its impact on adverse left ventricular (LV) remodeling is incompletely understood and is investigated here. METHODS AND RESULTS: Forty-eight ST-segment-elevation myocardial infarction patients underwent cardiovascular magnetic resonance at 4±2 days post primary percutaneous coronary intervention, of whom 40 had a follow-up scan at 5±2 months...
October 2016: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/27893652/correlation-between-t2-t2-star-relaxation-time-and-cervical-intervertebral-disc-degeneration-an-observational-study
#4
Minghua Huang, Yong Guo, Qiong Ye, Lei Chen, Kai Zhou, Qingjun Wang, Lixin Shao, Qinglei Shi, Chun Chen
PURPOSE: To demonstrate the potential benefits of T2 relaxation time of intervertebral discs (IVDs) regarding the detection and grading of degenerative disc disease using 3.0-T magnetic resonance imaging (MRI) in a clinical setting. MATERIALS AND METHODS: Cervical sagittal T2-weighted, T2 relaxation MRI was performed at 3.0-T in 61 subjects, covering discs C2-3 to C6-7. All discs were morphologically assessed based on the Pfirrmann grade, and regions of interests (ROIs) were drawn over the T2 mapping...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27888153/three-dimensional-black-blood-t2-mapping-with-compressed-sensing-and-data-driven-parallel-imaging-in-the-carotid-artery
#5
Jianmin Yuan, Ammara Usman, Scott A Reid, Kevin F King, Andrew J Patterson, Jonathan H Gillard, Martin J Graves
PURPOSE: To develop a 3D black-blood T2 mapping sequence with a combination of compressed sensing (CS) and parallel imaging (PI) for carotid wall imaging. MATERIALS AND METHODS: A 3D black-blood fast-spin-echo (FSE) sequence for T2 mapping with CS and PI was developed and validated. Phantom experiments were performed to assess T2 accuracy using a Eurospin Test Object, with different combination of CS and PI acceleration factors. A 2D multi-echo FSE sequence was used as a reference to evaluate the accuracy...
November 22, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27885476/does-t2-mapping-of-the-posterior-annulus-fibrosus-indicate-the-presence-of-lumbar-intervertebral-disc-herniation-a-3-0-tesla-magnetic-resonance-study
#6
Alina Messner, David Stelzeneder, Stefan Trattnig, Götz H Welsch, Martina Schinhan, Sebastian Apprich, Martin Brix, Reinhard Windhager, Siegfried Trattnig
PURPOSE: Indicating lumbar disc herniation via magnetic resonance imaging (MRI) T2 mapping in the posterior annulus fibrosus (AF). METHODS: Sagittal T2 maps of 313 lumbar discs of 64 patients with low back pain were acquired at 3.0 Tesla (3T). The discs were rated according to disc herniation and bulging. Region of interest (ROI) analysis was performed on median, sagittal T2 maps. T2 values of the AF, in the most posterior 10% (PAF-10) and 20% of the disc (PAF-20), were compared...
November 24, 2016: European Spine Journal
https://www.readbyqxmd.com/read/27882808/no-degeneration-found-in-focal-cartilage-defects-evaluated-with-dgemric-at-12-year-follow-up
#7
Cathrine Nørstad Engen, Sverre Løken, Asbjørn Årøen, Charles Ho, Lars Engebretsen
Background and purpose - The natural history of focal cartilage defects (FCDs) is still unresolved, as is the long-term cartilage quality after cartilage surgery. It has been suggested that delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) is a biomarker of early OA. We aimed to quantitatively evaluate the articular cartilage in knees with FCDs, 12 years after arthroscopic diagnosis. Patients and methods - We included 21 patients from a cohort of patients with knee pain who underwent arthroscopy in 1999...
November 24, 2016: Acta Orthopaedica
https://www.readbyqxmd.com/read/27872810/the-association-between-intra-and-juxta-cortical-pathology-and-cognitive-impairment-in-multiple-sclerosis-by-quantitative-t2-mapping-at-7%C3%A2-t-mri
#8
Céline Louapre, Sindhuja T Govindarajan, Costanza Giannì, Nancy Madigan, A Scott Nielsen, Jacob A Sloane, Revere P Kinkel, Caterina Mainero
Using quantitative T2* at 7 Tesla (T) magnetic resonance imaging, we investigated whether impairment in selective cognitive functions in multiple sclerosis (MS) can be explained by pathology in specific areas and/or layers of the cortex. Thirty-one MS patients underwent neuropsychological evaluation, acquisition of 7 T multi-echo T2* gradient-echo sequences, and 3 T anatomical images for cortical surfaces reconstruction. Seventeen age-matched healthy subjects served as controls. Cortical T2* maps were sampled at various depths throughout the cortex and juxtacortex...
2016: NeuroImage: Clinical
https://www.readbyqxmd.com/read/27866674/quantitative-t2-mapping-for-detection-and-quantification-of-thrombophlebitis-in-a-rabbit-model
#9
Dar Weiss, Oren M Rotman, Shmuel Einav
Short peripheral catheter thrombophlebitis (SPCT), a sterile inflammation of the vein wall, is the most common complication associated with short peripheral catheters (SPCs) and affects up to 80% of hospitalized patients receiving IV therapy. Extensive research efforts have been devoted for improvement and optimization of the catheter material, but means for examination of any novel design are limited, inaccurate and require costly comprehensive pre-clinical and clinical trials. Therefore, there is a conclusive need for a reliable quantitative method for evaluation of SPCT, in particular for research purposes examining the thrombophlebitis-related symptoms of any novel catheter design...
November 15, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/27856398/recovery-of-accurate-t2-from-historical-1-5-tesla-proton-density-and-t2-weighted-images-application-to-7-year-t2-changes-in-multiple-sclerosis-brain
#10
Md Nasir Uddin, Kelly C McPhee, Gregg Blevins, Alan H Wilman
OBJECTIVE: To determine accurate quantitative transverse relaxation times (T2) using retrospective clinical images and apply it to examine 7-year changes in multiple sclerosis (MS) brain. METHODS: A method for T2 mapping from retrospective proton density (PD) and T2-weighted fast spin echo images was recently introduced, but requires measurement of flip angles. We examined whether 1.5T flip angle variation in brain can be predicted, thus enabling T2 analysis of historical PD and T2-weighted images without a concurrent flip angle map...
November 14, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27855393/central-obesity-and-liver-iron-content-a-noninvasive-assessment-in-general-population-by-magnetic-resonance-imaging
#11
Amir Reza Radmard, Hossein Poustchi, Amir Pejman Hashemi Taheri, Marjan Gerami Seresht, Payam Mohammadinejad, Ali Yoonessi, Mehrdad Dadgostar, Mohammad Sadegh Rahmanian, Elham Jafari, Atefeh Zeinoddini, Reza Malekzadeh, Shahin Merat
BACKGROUND/AIM: Existing evidence points to an altered status of iron metabolism in obesity. We aimed to investigate whether central obesity is independently associated with estimated liver iron content (liver T2* value) in general population that used the noninvasive assessment method by MRI. METHODS: The study was carried out on 200 subjects randomly selected from the Golestan Cohort Study who underwent abdominal MRI. Quantitative T2* maps of entire cross-sectional area of liver were calculated using a semi-automated software for estimating the levels of iron content...
November 18, 2016: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/27854210/skeletal-muscle-quantitative-nuclear-magnetic-resonance-imaging-and-spectroscopy-as-an-outcome-measure-for-clinical-trials
#12
Pierre G Carlier, Benjamin Marty, Olivier Scheidegger, Paulo Loureiro de Sousa, Pierre-Yves Baudin, Eduard Snezhko, Dmitry Vlodavets
Recent years have seen tremendous progress towards therapy of many previously incurable neuromuscular diseases. This new context has acted as a driving force for the development of novel non-invasive outcome measures. These can be organized in three main categories: functional tools, fluid biomarkers and imagery. In the latest category, nuclear magnetic resonance imaging (NMRI) offers a considerable range of possibilities for the characterization of skeletal muscle composition, function and metabolism. Nowadays, three NMR outcome measures are frequently integrated in clinical research protocols...
March 3, 2016: Journal of Neuromuscular Diseases
https://www.readbyqxmd.com/read/27853488/changes-of-t2-relaxation-time-from-neoadjuvant-chemotherapy-in-breast-cancer-lesions
#13
Li Liu, Bo Yin, Dao Ying Geng, Yi Ping Lu, Wei Jun Peng
BACKGROUND: Neoadjuvant chemotherapy (NAC) is generally an effective method of reducing locally advanced malignant breast lesions before surgery; assessing the tumor response to NAC is crucial for patient management. T2 relaxation times can reflect biological state of lesions, may prove useful to assess the response to NAC. OBJECTIVES: To investigate the lesion T2 relaxation times change in breast cancer neoadjuvant chemotherapy (NAC). PATIENTS AND METHODS: In total, 26 patients underwent NAC...
July 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
https://www.readbyqxmd.com/read/27833407/comparison-of-t1rho-and-t2-mapping-of-knee-articular-cartilage-in-an-asymptomatic-population
#14
Min A Yoon, Suk-Joo Hong, A Lan Im, Chang Ho Kang, Baek Hyun Kim, In Seong Kim
OBJECTIVE: To analyze subregional differences in T1rho (T1ρ) and T2 values and their correlation in asymptomatic knee cartilage, and to evaluate angular dependence with magic angles. MATERIALS AND METHODS: Six asymptomatic volunteers underwent knee MRI with T1ρ and T2 mapping. T1ρ and T2 values were measured by two radiologists independently, at nine subregions in the medial femoral condyle (MFC) cartilage, at angles of ± 0°, 15°, 35°, 55°, 75° respective to a vertical line (B0) bisecting the width of the distal femur, and at two locations in the patella...
November 2016: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/27833406/interobserver-and-test-retest-reproducibility-of-t1%C3%AF-and-t2-measurements-of-lumbar-intervertebral-discs-by-3t-magnetic-resonance-imaging
#15
Yeon Hwa Yoo, Choon-Sik Yoon, Na Lae Eun, Moon-Jung Hwang, Hanna Yoo, Robert D Peters, Tae-Sub Chung, Young Han Lee, Jin-Suck Suh, Sungjun Kim
OBJECTIVE: To investigate the interobserver and test-retest reproducibility of T1ρ and T2 measurements of lumbar intervertebral discs using 3T magnetic resonance imaging (MRI). MATERIALS AND METHODS: This study included a total of 51 volunteers (female, 26; male, 25; mean age, 54 ± 16.3 years) who underwent lumbar spine MRI with a 3.0 T scanner. Amongst these subjects, 40 underwent repeat T1ρ and T2 measurement acquisitions with identical image protocol. Two observers independently performed the region of interest measurements in the nuclei pulposi of the discs from L1-2 through L5-S1 levels...
November 2016: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/27824492/evolution-of-intrameniscal-signal-intensity-alterations-detected-on-mri-over-24-months-in-patients-with-traumatic-anterior-cruciate-ligament-tear
#16
Julio Brandao Guimaraes, Luca Facchetti, Benedikt J Schwaiger, Alexandra S Gersing, Sharmila Majumdar, Benjamin C Ma, Xiaojuan Li, Thomas M Link
OBJECTIVE: The objective of our study was to assess the prevalence and evolution of intrameniscal signal-intensity alteration in subjects with an anterior cruciate ligament (ACL) tear over 24 months and compare clinical outcome and changes of cartilage between subjects with and those without this meniscal abnormality. MATERIALS AND METHODS: Fifty-seven subjects with an ACL tear were screened for intrameniscal signal-intensity alteration. Morphologic and compositional MRI was performed before ACL reconstruction and 12 and 24 months after ACL reconstruction...
November 8, 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/27807678/both-3-t-dgemric-and-acetabular-femoral-t2-difference-may-detect-cartilage-damage-at-the-chondrolabral-junction
#17
Tobias Hesper, Evgeny Bulat, Sarah Bixby, Alireza Akhondi-Asl, Onur Afacan, Patricia Miller, Garrett Bowen, Simon Warfield, Young-Jo Kim
BACKGROUND: In addition to case reports of gadolinium-related toxicities, there are increasing theoretical concerns about the use of gadolinium for MR imaging. As a result, there is increasing interest in noncontrast imaging techniques for biochemical cartilage assessment. Among them, T2 mapping holds promise because of its simplicity, but its biophysical interpretation has been controversial. QUESTIONS/PURPOSES: We sought to determine whether (1) 3-T delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) and T2 mapping are both capable of detecting cartilage damage at the chondrolabral junction in patients with femoroacetabular impingement (FAI); and (2) whether there is a correlation between these two techniques for acetabular and femoral head cartilage assessment...
November 2, 2016: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/27803472/effect-of-surfactants-and-thickeners-on-the-stability-of-menthol-diphenhydramine-cream-identified-by-magnetic-resonance-imaging
#18
Yoshinori Onuki, Masamitsu Yokokawa, Shunichi Utsumi, Yasuko Obata, Yoshiaki Machida, Chieko Seike, Yoshihiro Hayashi, Kozo Takayama
A menthol-diphenhydramine cream is prepared in hospital pharmacies and then prescribed to patients for the treatment of pruritus associated with chronic kidney disease. The purpose of this study is to design a stable formulation without any concern about phase separation during its clinical use on patients. As a preventive measure against phase separation, various surfactants and thickeners were incorporated into the creams. The test creams were stored at 40°C, and then their phase separation behaviors were monitored...
2016: Chemical & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/27791285/signal-to-noise-ratio-t2-and-t2-for-hyperpolarized-helium-3-mri-of-the-human-lung-at-three-magnetic-field-strengths
#19
Peter Komlosi, Talissa A Altes, Kun Qing, Karen E Mooney, G Wilson Miller, Jaime F Mata, Eduard E de Lange, William A Tobias, Gordon D Cates, John P Mugler
PURPOSE: To evaluate T2 , T2*, and signal-to-noise ratio (SNR) for hyperpolarized helium-3 ((3) He) MRI of the human lung at three magnetic field strengths ranging from 0.43T to 1.5T. METHODS: Sixteen healthy volunteers were imaged using a commercial whole body scanner at 0.43T, 0.79T, and 1.5T. Whole-lung T2 values were calculated from a Carr-Purcell-Meiboom-Gill spin-echo-train acquisition. T2* maps and SNR were determined from dual-echo and single-echo gradient-echo images, respectively...
October 28, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/27785816/in-vivo-skin-moisturizing-measurement-by-high-resolution-3-tesla-magnetic-resonance-imaging
#20
J Mesrar, J Ognard, M Garetier, D Chechin, L Misery, D Ben Salem
BACKGROUND: Magnetic resonance imaging (MRI) is rarely used for the exploration of skin, even if studies have validated both feasibility of skin MRI and its interest for anatomical, physiological, and biochemical study of the skin. The purpose of this study is to explore moisturizing of the different skin layers using 3-T scan. METHODS: An MRI of the heel's skin was performed using a 23 mm coil diameter on a 3T scan with a FFE (Fast Field Echo) 3D T1-weighted sequence and a TSE (Turbo Spin Echo) calculation T2-weighted sequence (pixels size of respectively 60 and 70 μm)...
October 27, 2016: Skin Research and Technology
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