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T2-mapping

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https://www.readbyqxmd.com/read/29136120/t2-mapping-cardiovascular-magnetic-resonance-identifies-the-presence-of-myocardial-inflammation-in-patients-with-dilated-cardiomyopathy-as-compared-to-endomyocardial-biopsy
#1
M Spieker, E Katsianos, M Gastl, P Behm, P Horn, C Jacoby, B Schnackenburg, P Reinecke, M Kelm, R Westenfeld, F Bönner
Aims: The aim of this study was to determine the value of T2 mapping for the non-invasive assessment of myocardial inflammation in different stages of systolic left ventricular dysfunction in dilated cardiomyopathy (DCM) in comparison with endomyocardial biopsy (EMB). Methods and results: A total of 132 subjects were enrolled between 2013 and 2016 (62 controls and 70 patients with DCM). All patients underwent CMR at 1.5 T and received coronary angiogram and EMB...
November 10, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29136015/the-influences-of-walking-running-and-stair-activity-on-knee-articular-cartilage-quantitative-mri-using-t1-rho-and-t2-mapping
#2
Meng Chen, Lin Qiu, Si Shen, Fei Wang, Jing Zhang, Cici Zhang, Sirun Liu
OBJECTIVE: To explore the different influences of walking, running and stair activity on knee articular cartilage with T1 rho and T2 mapping sequences. MATERIALS AND METHODS: MRI (3.0-T) scans of the right knee were performed in twenty-three young healthy adults immediately after 30 minutes of rest, walking, running and stair activity respectively. Articular cartilage was quantitatively assessed based on T1 rho and T2 relaxation times. Analysis of variance for random block design data, bonferroni test and paired samples t tests were performed to estimate the different influences of physiological activities on articular cartilage...
2017: PloS One
https://www.readbyqxmd.com/read/29126367/t2-mapping-of-acetabular-cartilage-in-patients-with-femoroacetabular-impingement-at-3-tesla-comparative-analysis-with-arthroscopic-findings
#3
Tobias Hesper, Christina Neugroda, Christoph Schleich, Gerald Antoch, Harish Hosalkar, Rüdiger Krauspe, Christoph Zilkens, Bernd Bittersohl
Objective To evaluate the diagnostic accuracy of T2*-mapping for detecting acetabular cartilage damage in patients with symptomatic femoroacetabular impingement (FAI). Design A total of 29 patients (17 females, 12 males, mean age 35.6 ± 12.8 years, mean body mass index 25.1 ± 4.1 kg/m(2), 16 right hips) with symptomatic FAI underwent T2* MRI and subsequent hip arthroscopy. T2* values were obtained by region of interest analysis in seven radially reformatted planes around the femoral neck (anterior, anterior-superior, superior-anterior, superior, superior-posterior, posterior-superior, posterior)...
November 1, 2017: Cartilage
https://www.readbyqxmd.com/read/29123919/t2-mapping-and-post-contrast-t1-dgemric-of-the-patellar-cartilage-12-year-follow-up-after-patellar-stabilizing-surgery-in-childhood
#4
Eva Bengtsson Moström, Eveliina Lammentausta, Thröstur Finnbogason, Lars Weidenhielm, Per-Mats Janarv, Carl Johan Tiderius
Background: Cartilage degeneration has been reported after recurrent patellar dislocation. However, effects of surgical stabilization in childhood have not yet been described. Purpose: To examine the cartilage quality in very young adults operated with a patellar stabilizing procedure due to recurrent patellar dislocation in childhood, and evaluate if cartilage quality correlates with clinical parameters and patient-reported outcomes. Material and Methods: Seventeen patients were investigated ≥ 5 years (mean = 11...
October 2017: Acta Radiologica Open
https://www.readbyqxmd.com/read/29121971/cmr-based-blood-oximetry-via-multi-parametric-estimation-using-multiple-t2-measurements
#5
Juliet Varghese, Lee C Potter, Richard LaFountain, Xueliang Pan, Subha V Raman, Rizwan Ahmad, Orlando P Simonetti
BACKGROUND: Measurement of blood oxygen saturation (O2 saturation) is of great importance for evaluation of patients with many cardiovascular diseases, but currently there are no established non-invasive methods to measure blood O2 saturation in the heart. While T2-based CMR oximetry methods have been previously described, these approaches rely on technique-specific calibration factors that may not generalize across patient populations and are impractical to obtain in individual patients...
November 9, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29120023/role-of-liver-magnetic-resonance-imaging-in-hyperferritinaemia-and-the-diagnosis-of-iron-overload
#6
Axel Ruefer, Christine Bapst, Rudolf Benz, Jens Bremerich, Nathan Cantoni, Laura Infanti, Kaveh Samii, Mathias Schmid, Jean-Paul Vallée
Hyperferritinaemia is a frequent clinical problem. Elevated serum ferritin levels can be detected in different genetic and acquired diseases and can occur with or without anaemia. It is therefore important to determine whether hyperferritinaemia is due to iron overload or due to a secondary cause. The main causes of iron overload are intestinal iron hyperabsorption disorders and transfusion-dependent disorders. Iron homeostasis and iron overload are quantified by different diagnostic approaches. The evaluation of serum ferritin and transferrin saturation is the first diagnostic step to identify the cause of hyperferritinaemia...
November 9, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/29103482/quantitative-evaluation-of-knee-cartilage-and-meniscus-destruction-in-patients-with-rheumatoid-arthritis-using-t1%C3%AF-and-t2-mapping
#7
Xiang Hong Meng, Zhi Wang, Li Guo, Xiu Chan Liu, Yu Wei Zhang, Ze Wei Zhang, Xin Long Ma
OBJECTIVE: To calculate T1ρ and T2 values of articular cartilage and menisci in knee joints of patients with RA, and compare the values between RA patients and healthy volunteers, to gain insight into the pathogenesis of cartilage and meniscus degradation in patients with RA. MATERIALS AND METHODS: Nine patients with RA and knee joints symptoms were enrolled in the study, twenty healthy volunteers without knee joint diseases were included as controls. Sagittal fat-saturated T1ρ and T2 mapping images were obtained on a 3T MR scanner (GE750, GE Healthcare, Waukesha, WI), using a dedicated 8-channel knee coil...
November 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/29101365/biomineral-nano-theranostic-agent-for-magnetic-resonance-image-guided-augmented-radiofrequency-ablation-of-liver-tumor
#8
Anusha Ashokan, Vijay Harish Somasundaram, Genekehal Siddaramana Gowd, Ida M Anna, Giridharan L Malarvizhi, Badrinathan Sridharan, Rupal B Jobanputra, Reshmi Peethambaran, A K K Unni, Shantikumar Nair, Manzoor Koyakutty
Theranostic nanoparticles based on biocompatible mineral compositions can significantly improve the translational potential of image guided cancer nano-therapy. Here, we report development of a single-phase calcium phosphate biomineral nanoparticle (nCP) with dual-mode magnetic resonance contrast (T1-T2) together with radiofrequency (RF) mediated thermal response suitable for image-guided RF ablation of cancer. The nanoparticles (NP) are engineered to provide dual MR contrast by an optimized doping concentration (4...
November 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29091314/variable-angle-gray-level-co-occurrence-matrix-analysis-of-t2-relaxation-time-maps-reveals-degenerative-changes-of-cartilage-in-knee-osteoarthritis-oulu-knee-osteoarthritis-study
#9
Arttu Peuna, Joonas Hekkala, Marianne Haapea, Jana Podlipská, Ali Guermazi, Simo Saarakkala, Miika T Nieminen, Eveliina Lammentausta
BACKGROUND: Texture analysis methods based on gray level co-occurrence matrices (GLCM) can be optimized to probe the spatial correspondence information from knee MRI T2 maps and the changes caused by osteoarthritis, and thus possibly leading to a more sensitive characterization of osteoarthritic cartilage. Curvature of the cartilage surfaces combined with the low image resolution in relation to cartilage thickness set special requirements for an effective texture analysis tool. PURPOSE/HYPOTHESIS: To introduce a novel implementation of GLCM algorithm optimized for cartilage texture analysis; to evaluate the performance of the designed algorithm against mean T2 relaxation time analysis; and to identify the most suitable texture features for discerning osteoarthritic subjects and asymptomatic controls...
November 1, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29083524/automated-vessel-exclusion-technique-for-quantitative-assessment-of-hepatic-iron-overload-by-r2-mri
#10
Aaryani Tipirneni-Sajja, Ruitian Song, M Beth McCarville, Ralf B Loeffler, Jane S Hankins, Claudia M Hillenbrand
BACKGROUND: Extraction of liver parenchyma is an important step in the evaluation of R2*-based hepatic iron content (HIC). Traditionally, this is performed by radiologists via whole-liver contouring and T2*-thresholding to exclude hepatic vessels. However, the vessel exclusion process is iterative, time-consuming, and susceptible to interreviewer variability. PURPOSE: To implement and evaluate an automatic hepatic vessel exclusion and parenchyma extraction technique for accurate assessment of R2*-based HIC...
October 30, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29069207/myocardial-edema-without-fibrosis-by-magnetic-resonance-t2-mapping-in-acute-chagas-myocarditis
#11
Andréa Silvestre de Sousa, Maria Eduarda Derenne, Alejandro Marcel Hasslocher-Moreno, Sérgio Salles Xavier, Ilan Gottlieb
No abstract text is available yet for this article.
October 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/29042929/quantitative-assessment-of-salvaged-myocardial-zone-and-intramyocardial-hemorrhage-using-non-contrast-faster-t2-mapping-in-a-rat-model-by-7t-mri
#12
Yan Zhang, Yini Xu, Lei Wang, Yushu Chen, Ruiqing Tian, Jun Jiao, Hong Xie, Li Yang, Fabao Gao
The aim of this study was to determine the myocardial area at risk (AAR), infarction-core size (IS) and the salvaged myocardial zone (SMZ), and to evaluate the imaging and histological characteristics of intramyocardial hemorrhage (IMH) after myocardial infarction using non-contrast T2 mapping on 7T magnetic resonance imaging (MRI). Twenty Sprague Dawley (SD) rats were randomly divided into the sham and model groups (n=10 in each). In the model group, myocardial infarction models were established by left anterior descending branch ligation...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29038932/mr-t2-value-of-the-tibial-nerve-can-be-used-as-a-potential-non-invasive-and-quantitative-biomarker-for-the-diagnosis-of-diabetic-peripheral-neuropathy
#13
Dongye Wang, Chuan Wang, Xiaohui Duan, Zehong Yang, Zhiqiang Bai, Huijun Hu, Li Yan, Jun Shen
OBJECTIVE: To determine the role of quantitative tibial nerve T2 value in the diagnosis of diabetic peripheral neuropathy (DPN). METHODS: MR imaging and T2 mapping of the tibial nerve were performed in 22 diabetic patients with DPN, 20 diabetic patients without DPN and 20 healthy controls. Nerve T2 values were measured, and compared using the Mann-Whitney U test. Receiver operating characteristic (ROC) curve analysis was used to determine the diagnostic ability of T2 value to identify DPN...
October 16, 2017: European Radiology
https://www.readbyqxmd.com/read/29031987/intra-articular-injection-of-mesenchymal-stem-cells-and-platelet-rich-plasma-to-treat-patellofemoral-osteoarthritis-preliminary-results-of-a-long-term-pilot-study
#14
Julien Pintat, Alain Silvestre, Guy Magalon, Alain Pierre Gadeau, Lionel Pesquer, Anne Perozziello, Alain Peuchant, Charbel Mounayer, Benjamin Dallaudière
PURPOSE: To assess the feasibility and safety of concomitant intra-articular (IA) knee injection of mesenchymal stem cells (MSCs) and platelet-rich plasma (PRP) under fluoroscopic guidance to treat patellofemoral osteoarthritis (OA). MATERIALS AND METHODS: This prospective study included 19 consecutive patients referred for fluoroscopically guided IA MSC and PRP injection for symptomatic patellofemoral chondropathy in which conservative treatment had failed. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score and magnetic resonance (MR) data, including T2 mapping sequence, were prospectively collected before and 6 months after treatment...
October 12, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28986624/significant-changes-of-t2-value-in-the-peripheral-zone-and-seminal-vesicles-after-ejaculation
#15
Takeshi Shin, Yasushi Kaji, Toshiro Shukuya, Miwako Nozaki, Shigehiro Soh, Hiroshi Okada
OBJECTIVES: To analyse the quantitative changes of the prostate and seminal vesicles (SV) on magnetic resonance imaging (MRI) after ejaculation. METHODS: Ten healthy young males were enrolled for T2-weighted and T2 mapping MRI before and after two consecutive ejaculations. T2 values of the peripheral zone (PZ) and the central gland (CG) at the midgland of the prostate were compared before and after ejaculation, respectively. T2 values of the PZ at the apex and base were also compared before and after, respectively...
October 6, 2017: European Radiology
https://www.readbyqxmd.com/read/28986407/ferumoxytol-enhanced-magnetic-resonance-imaging-in-acute-myocarditis
#16
Colin G Stirrat, Shirjel R Alam, Thomas J MacGillivray, Calum D Gray, Marc R Dweck, Kevin Dibb, Nick Spath, John R Payne, Sanjay K Prasad, Roy S Gardner, Saeed Mirsadraee, Peter A Henriksen, Scott Ik Semple, David E Newby
OBJECTIVES: Ultrasmall superparamagnetic particles of iron oxide (USPIO)-enhanced MRI can detect tissue-resident macrophage activity and identify cellular inflammation within tissues. We hypothesised that USPIO-enhanced MRI would provide a non-invasive imaging technique that would improve the diagnosis and management of patients with acute myocarditis. METHODS: Ten volunteers and 14 patients with suspected acute myocarditis underwent T2, T2* and late gadolinium enhancement (LGE) 3T MRI, with further T2* imaging at 24 hours after USPIO (ferumoxytol, 4 mg/kg) infusion, at baseline and 3 months...
October 6, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28982571/role-of-cardiac-magnetic-resonance-in%C3%A2-the%C3%A2-diagnosis-and-prognosis-of%C3%A2-nonischemic%C3%A2-cardiomyopathy
#17
REVIEW
Amit R Patel, Christopher M Kramer
Cardiac magnetic resonance (CMR) is a valuable tool for the evaluation of patients with, or at risk for, heart failure and has a growing impact on diagnosis, clinical management, and decision making. Through its ability to characterize the myocardium by using multiple different imaging parameters, it provides insight into the etiology of the underlying heart failure and its prognosis. CMR is widely accepted as the reference standard for quantifying chamber size and ejection fraction. Additionally, tissue characterization techniques such as late gadolinium enhancement (LGE) and other quantitative parameters such as T1 mapping, both native and with measurement of extracellular volume fraction; T2 mapping; and T2* mapping have been validated against histological findings in a wide range of clinical scenarios...
October 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28982099/t1-and-t2-mapping-the-next-giant-leap-in-cardiac-imaging
#18
Mateusz Śpiewak
No abstract text is available yet for this article.
October 6, 2017: Cardiology
https://www.readbyqxmd.com/read/28979849/clinical-applications-of-advanced-magnetic-resonance-imaging-techniques-for-arthritis-evaluation
#19
REVIEW
Teodoro Martín Noguerol, Antonio Luna, Marta Gómez Cabrera, Alexie D Riofrio
Magnetic resonance imaging (MRI) has allowed a comprehensive evaluation of articular disease, increasing the detection of early cartilage involvement, bone erosions, and edema in soft tissue and bone marrow compared to other imaging techniques. In the era of functional imaging, new advanced MRI sequences are being successfully applied for articular evaluation in cases of inflammatory, infectious, and degenerative arthropathies. Diffusion weighted imaging, new fat suppression techniques such as DIXON, dynamic contrast enhanced-MRI, and specific T2 mapping cartilage sequences allow a better understanding of the physiopathological processes that underlie these different arthropathies...
September 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28962127/multimodal-quantitative-magnetic-resonance-imaging-for-lumbar-intervertebral-disc-degeneration
#20
Wei Wang, Jin Hou, Deyong Lv, Wen Liang, Xinqing Jiang, Hongbin Han, Xianyue Quan
The present study investigated the application of the T1ρ and T2 relaxation mapping magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI) in the evaluation of intervertebral disc degeneration (IDD). A total of 93 asymptomatic subjects were imaged with T1ρ and T2 mapping, as well as DWI. Pfirrmann grading was performed and correlation analysis was conducted for T1ρ, T2 and DWI results with the grading results and age. Pfirrmann grading indicated 69 cases of grade I, 240 cases of grade II, 101 cases of grade III, 43 cases of grade IV and 12 cases of grade V...
September 2017: Experimental and Therapeutic Medicine
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