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T2-mapping

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https://www.readbyqxmd.com/read/28543430/planet-an-ellipse-fitting-approach-for-simultaneous-t1-and-t2-mapping-using-phase-cycled-balanced-steady-state-free-precession
#1
Yulia Shcherbakova, Cornelis A T van den Berg, Chrit T W Moonen, Lambertus W Bartels
PURPOSE: To demonstrate the feasibility of a novel, ellipse fitting approach, named PLANET, for simultaneous estimation of relaxation times T1 and T2 from a single 3D phase-cycled balanced steady-state free precession (bSSFP) sequence. METHODS: A method is presented in which the elliptical signal model is used to describe the phase-cycled bSSFP steady-state signal. The fitting of the model to the acquired data is reformulated into a linear convex problem, which is solved directly by a linear least squares method, specific to ellipses...
May 22, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28536472/quantifying-the-area-at-risk-of-myocardial-infarction-in-vivo-using-arterial-spin-labeling-cardiac-magnetic-resonance
#2
Rachel K Dongworth, Adrienne E Campbell-Washburn, Hector A Cabrera-Fuentes, Heerajnarain Bulluck, Thomas Roberts, Anthony N Price, Sauri Hernández-Reséndiz, Roger J Ordidge, David L Thomas, Derek M Yellon, Mark F Lythgoe, Derek J Hausenloy
T2-weighted cardiovascular magnetic resonance (T2-CMR) of myocardial edema can quantify the area-at-risk (AAR) following acute myocardial infarction (AMI), and has been used to assess myocardial salvage by new cardioprotective therapies. However, some of these therapies may reduce edema, leading to an underestimation of the AAR by T2-CMR. Here, we investigated arterial spin labeling (ASL) perfusion CMR as a novel approach to quantify the AAR following AMI. Adult B6sv129-mice were subjected to in vivo left coronary artery ligation for 30 minutes followed by 72 hours reperfusion...
May 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28528429/myocardial-edema-in-acute-myocarditis-relationship-of-t2-relaxometry-and-late-enhancement-burden-by-using-dual-contrast-turbo-spin-echo-mri
#3
A Mayr, G Klug, H J Feistritzer, S J Reinstadler, M Reindl, R Esterhammer, G Feuchtner, B Metzler, M F Schocke
To quantify myocardial edema by using a T2 relaxometry approach with a dual-contrast turbo spin-echo (dcTSE) sequence in patients with acute myocarditis regarding focal late gadolinium enhancement (LGE) burden. CMR T2 relaxometry was performed in 39 patients (age 41 ± 19 years; 36% women) with LGE in a typical myocarditis pattern and in ten healthy volunteers (age 46 ± 12; 60% woman). dcTSE sequence (echo time 29 and 75 ms, respectively) was used for T2 mapping, analysis were performed on the basis of region of interest (ROI)...
May 20, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28521823/t1rho-and-t2-relaxation-times-of-the-normal-adult-knee-meniscus-at-3t-analysis-of-zonal-differences
#4
Shoichiro Takao, Tan B Nguyen, Hon J Yu, Shigeo Hagiwara, Yasuhito Kaneko, Taiki Nozaki, Seiji Iwamoto, Maki Otomo, Ran Schwarzkopf, Hiroshi Yoshioka
BACKGROUND: Prior studies describe histological and immunohistochemical differences in collagen and proteoglycan content in different meniscal zones. The aim of this study is to evaluate horizontal and vertical zonal differentiation of T1rho and T2 relaxation times of the entire meniscus from volunteers without symptom and imaging abnormality. METHODS: Twenty volunteers age between 19 and 38 who have no knee-related clinical symptoms, and no history of prior knee surgeries were enrolled in this study...
May 18, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28516485/simultaneous-measurement-of-t2-and-apparent-diffusion-coefficient-t2-adc-in-the-heart-with-motion-compensated-spin-echo-diffusion-weighted-imaging
#5
Eric Aliotta, Kévin Moulin, Zhaohuan Zhang, Daniel B Ennis
PURPOSE: To evaluate a technique for simultaneous quantitative T2 and apparent diffusion coefficient (ADC) mapping in the heart (T2 +ADC) using spin echo (SE) diffusion-weighted imaging (DWI). THEORY AND METHODS: T2 maps from T2 +ADC were compared with single-echo SE in phantoms and with T2 -prepared (T2 -prep) balanced steady-state free precession (bSSFP) in healthy volunteers. ADC maps from T2 +ADC were compared with conventional DWI in phantoms and in vivo. T2 +ADC was also demonstrated in a patient with acute myocardial infarction (MI)...
May 17, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28512063/influence-of-delayed-gadolinium-enhanced-mri-of-cartilage-dgemric-protocol-on-t2-mapping-is-it-possible-to-comprehensively-assess-knee-cartilage-composition-in-one-post-contrast-mr-examination-at-3-tesla
#6
Joost Verschueren, Jasper van Tiel, Max Reijman, Esther E Bron, Stefan Klein, Jan A N Verhaar, Sita Bierma-Zeinstra, Gabriel P Krestin, Piotr A Wielopolski, Edwin H G Oei
OBJECTIVE: To evaluate the possibility of assessing knee cartilage with T2-mapping and delayed Gadolinium Enhanced MRI of Cartilage (dGEMRIC) in one post-contrast MR examination at 3 Tesla (T). DESIGN: T2 mapping was performed in 10 healthy volunteers at baseline; directly after baseline; after 10 minutes of cycling; and after 90 minutes delay, and in 16 osteoarthritis patients before and after intravenous administration of a double dose gadolinium dimeglumine contrast agent, reflecting key dGEMRIC protocol elements...
May 13, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28503732/imaging-short-lived-reactive-oxygen-species-ros-with-endogenous-contrast-mri
#7
Rong-Wen Tain, Alessandro M Scotti, Weiguo Li, Xiaohong Joe Zhou, Kejia Cai
PURPOSE: To characterize the relaxation properties of reactive oxygen species (ROS) for the development of endogenous ROS contrast magnetic resonance imaging (MRI). MATERIALS AND METHODS: ROS-producing phantoms and animal models were imaged at 9.4T MRI to obtain T1 and T2 maps. Egg white samples treated with varied concentrations of hydrogen peroxide (H2 O2 ) were used to evaluate the effect of produced ROS in T1 and T2 for up to 4 hours. pH and temperature changes due to H2 O2 treatment in egg white were also monitored...
May 15, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28500368/advanced-myocardial-tissue-characterisation-by-a-multi-component-cmr-protocol-in-patients-with-rheumatoid-arthritis
#8
Simon Greulich, Agnes Mayr, Daniel Kitterer, Joerg Latus, Joerg Henes, Francesco Vecchio, Philipp Kaesemann, Alexandru Patrascu, Andreas Greiser, Stefan Groeninger, Francesco Romeo, Niko Braun, M Dominik Alscher, Udo Sechtem, Heiko Mahrholdt
OBJECTIVES: Rheumatoid arthritis (RA) patients are at increased risk of suffering from adverse cardiovascular events. Cardiovascular magnetic resonance (CMR) mapping techniques might be appropriate tools to complement late gadolinium enhancement (LGE) for the assessment of myocardial involvement. This study aimed to perform advanced myocardial tissue characterisation in RA patients by a multicomponent CMR protocol. METHODS: 22 RA patients were prospectively enrolled and underwent CMR, including LGE and T1/T2 mapping sequences; 20 volunteers served as controls...
May 12, 2017: European Radiology
https://www.readbyqxmd.com/read/28497231/t2-mapping-and-t2-imaging-in-heart-failure
#9
REVIEW
A S Lota, P D Gatehouse, R H Mohiaddin
Cardiovascular magnetic resonance (CMR) is a versatile imaging modality that enables aetiological assessment and provides additional information to that of standard echocardiography in a significant proportion of patients with heart failure. In addition to highly accurate and reproducible assessment of ventricular volumes and replacement fibrosis, multiparametric mapping techniques have rapidly evolved to further expand the diagnostic and prognostic applications in various conditions ranging from acute inflammatory and ischaemic cardiomyopathy, to cardiac involvement in systemic diseases such as sarcoidosis and iron overload cardiomyopathy...
May 11, 2017: Heart Failure Reviews
https://www.readbyqxmd.com/read/28496138/severe-bilateral-ischemic-reperfusion-renal-injury-hyperacute-and-acute-changes-in-apparent-diffusion-coefficient-t1-and-t2-mapping-with-immunohistochemical-correlations
#10
Sheung-Fat Ko, Hon-Kan Yip, Yen-Yi Zhen, Chia-Chang Lee, Chen-Chang Lee, Shyh-Jer Huang, Chung-Cheng Huang, Shu-Hang Ng, Jui-Wei Lin
The aim of this study was to investigate the hyperacute and acute changes in apparent diffusion coefficient (ADC), T1, and T2 mapping in rat kidneys after severe bilateral renal ischemic-reperfusion injury (IRI). After baseline MRI, 24 Spraque-Dawley rats with renal IRI were divided equally as group 1 (post-IRI MRI at 6 hours, days 1, 3, and 7) and groups 2, 3, and 4 (post-IRI MRI at 6 hours; 6 hours and day 1; 6 hours, days 1 and 3, respectively), while six other rats without IRI (group 5) were used as sham control...
May 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28489309/isotropic-three-dimensional-t2-mapping-of-knee-cartilage-development-and-validation
#11
Roberto Colotti, Patrick Omoumi, Gabriele Bonanno, Jean-Baptiste Ledoux, Ruud B van Heeswijk
PURPOSE: 1) To implement a higher-resolution isotropic 3D T2 mapping technique that uses sequential T2 -prepared segmented gradient-recalled echo (Iso3DGRE) images for knee cartilage evaluation, and 2) to validate it both in vitro and in vivo in healthy volunteers and patients with knee osteoarthritis. MATERIALS AND METHODS: The Iso3DGRE sequence with an isotropic 0.6 mm spatial resolution was developed on a clinical 3T MR scanner. Numerical simulations were performed to optimize the pulse sequence parameters...
May 10, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28483684/detection-of-botulinum-toxin-muscle-effect-in-humans-using-magnetic-resonance-imaging-a-case-series
#12
Michael W O'Dell, Mark Villanueva, Carly Creelman, Gaurav Telhan, Jaclyn Nestor, Keith D Hentel, Douglas Ballon, Jonathan Dyke
BACKGROUND: Although important for dosing and dilution, there are few data describing botulinum toxin (BT) movement in human muscle. OBJECTIVE: To better understand BT movement within human muscle DESIGN: Proof of concept study with descriptive case series SETTING: Outpatient academic practice PARTICIPANTS: Five subjects with stroke who were BT naïve with a mean age=60.4±14y and time post-stroke=4.6±3.7y. METHODS: Three standardized injections were given to the lateral gastrocnemius muscle (LGM): 2 contained 25 units (U) of onobotulinumtoxinA (Botox™) in 0...
May 5, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28480603/a-single-shot-t2-mapping-protocol-based-on-echo-split-gradient-spin-echo-acquisition-and-parametric-multiplexed-sensitivity-encoding-based-on-projection-onto-convex-sets-reconstruction
#13
Mei-Lan Chu, Hing-Chiu Chang, Koichi Oshio, Nan-Kuei Chen
PURPOSE: To develop a high-speed T2 mapping protocol that is capable of accurately measuring T2 relaxation time constants from a single-shot acquisition. THEORY: A new echo-split single-shot gradient-spin-echo (GRASE) pulse sequence is developed to acquire multicontrast data while suppressing signals from most nonprimary echo pathways in Carr-Purcell-Meiboom-Gill (CPMG) echoes. Residual nonprimary pathway signals are taken into consideration when performing T2 mapping using a parametric multiplexed sensitivity encoding based on projection onto convex sets (parametric-POCSMUSE) reconstruction method that incorporates extended phase graph modeling of GRASE signals...
May 7, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28473964/t1%C3%AF-t2-mapping-and-histopathology-of-degenerative-cartilage-in-advanced-knee-osteoarthritis
#14
Benjamin S Kester, Philip M Carpenter, Hon J Yu, Taiki Nozaki, Yasuhito Kaneko, Hiroshi Yoshioka, Ran Schwarzkopf
AIM: To investigate whether normal thickness cartilage in osteoarthritic knees demonstrate depletion of proteoglycan or collagen content compared to healthy knees. METHODS: Magnetic resonance (MR) images were acquired from 5 subjects scheduled for total knee arthroplasty (TKA) (mean age 70 years) and 20 young healthy control subjects without knee pain (mean age 28.9 years). MR images of T1ρ mapping, T2 mapping, and fat suppressed proton-density weighted sequences were obtained...
April 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28466651/t2-mapping-of-the-hip-in-asymptomatic-volunteers-with-normal-cartilage-morphology-an-analysis-of-regional-and-age-dependent-distribution
#15
Tobias Hesper, Christoph Schleich, Alexander Buchwald, Harish S Hosalkar, Gerald Antoch, Rüdiger Krauspe, Christoph Zilkens, Bernd Bittersohl
Objective To assess age-dependent and regional differences in T2* relaxation measurements in hip joint cartilage of asymptomatic volunteers at 3 T. Design Three age cohorts (cohort 1: age 20-30 years, 15 individuals; cohort 2: age 30-40 years, 17 individuals; cohort 3: age 40-50 years, 15 individuals) were enrolled. T2* values were obtained in the central and peripheral cartilage of the acetabulum and the femoral head in 7 regions (anterior to superior and posterior). Results T2* did not differ among age cohorts in acetabular cartilage (cohort 1: 24...
December 1, 2016: Cartilage
https://www.readbyqxmd.com/read/28466650/t2-mapping-for-hip-joint-cartilage-assessment-pre-mri-exercise-and-time-of-imaging-do-not-bias-the-t2-measurement-in-asymptomatic-volunteers
#16
Tobias Hesper, Harish S Hosalkar, Christoph Schleich, Gerald Antoch, Götz H Welsch, Rüdiger Krauspe, Christoph Zilkens, Bernd Bittersohl
Objective To identify if the time of day and pre-imaging exercise matter while performing T2* mapping of hip joint cartilage at 3 T. Design Nine asymptomatic healthy volunteers (mean age 27.4 ± 4.0 years) with no obvious morphological evidence of cartilage damage were enrolled. The MRI protocol included a double-echo steady state (DESS) sequence for morphological cartilage assessment and a multi-echo data image combination sequence for the T2* measurement. T2* values were obtained between 8 and 11 a.m., between 3 and 6 p...
August 1, 2016: Cartilage
https://www.readbyqxmd.com/read/28460192/proton-density-fat-fraction-of-rotator-cuff-muscles-is-associated-with-isometric-strength-10-years-after-rotator-cuff-repair-a-quantitative-magnetic-resonance-imaging-study-of-the-shoulder
#17
Dimitrios C Karampinos, Christian Holwein, Stefan Buchmann, Thomas Baum, Stefan Ruschke, Alexandra S Gersing, Reto Sutter, Andreas B Imhoff, Ernst J Rummeny, Pia M Jungmann
BACKGROUND: Quantitative muscle fat-fraction magnetic resonance (MR) imaging techniques correlate with semiquantitative Goutallier scores with failure after rotator cuff (RC) repair. PURPOSE: To investigate the relationship of proton density fat fraction (PDFF) of the RC muscles with semiquantitative MR scores, cartilage T2 relaxation times, and clinical isometric strength measurements in patients 10 years after unilateral RC repair. STUDY DESIGN: Cross-sectional study; Level of evidence, 3...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28459736/advanced-mri-of-the-optic-nerve
#18
Michael J Hoch, Mary T Bruno, Timothy M Shepherd
BACKGROUND: Clinical orbital MRI protocols are routinely used to study the optic nerves and exclude compressive lesions, infarctions, or inflammation. However, the small caliber and divergent oblique orientations of the optic nerves make it challenging to characterize them well with conventional MRI, especially since adjacent air-filled bony structures distort the MRI signal and motion is a problem even in cooperative, healthy volunteers. EVIDENCE ACQUISITION: Over the past 3 years we have experimented with multiple novel MRI approaches and sequences to better characterize the optic nerves...
June 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28458370/stability-of-mixed-preparations-consisting-of-commercial-moisturizing-creams-with-an-ointment-base-investigated-by-magnetic-resonance-imaging
#19
Yoshinori Onuki, Chiaki Funatani, Yoshihisa Yamamoto, Toshiro Fukami, Tatsuo Koide, Yoshihiro Hayashi, Kozo Takayama
A moisturizing cream mixed with a steroid ointment is frequently prescribed to patients suffering from atopic dermatitis. However, there is a concern that the mixing operation causes destabilization. The present study was performed to investigate the stability of such preparations closely using magnetic resonance imaging (MRI). As sample preparations, five commercial moisturizing creams that are popular in Japan were mixed with an ointment base, a white petrolatum, at a volume ratio of 1 : 1. The mixed preparations were stored at 60°C to accelerate the destabilization processes...
2017: Chemical & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28456927/associations-of-three-dimensional-t1-rho-mr-mapping-and-three-dimensional-t2-mapping-with-macroscopic-and-histologic-grading-as-a-biomarker-for-early-articular-degeneration-of-knee-cartilage
#20
T Sasho, J Katsuragi, S Yamaguchi, H Haneishi, T Aizimu, T Tanaka, A Watanabe, Y Sato, R Akagi, K Matsumoto, T Uno, K Motoori
T1 rho and T2 mapping are magnetic resonance imaging (MRI) techniques to detect early degenerative changes in cartilage. Recent advancements have enabled 3D acquisition for both techniques. The objective of the present study was to examine the correlation of 3D T1 rho and 3D T2 mapping with macroscopic and histological characteristics of knee cartilage. Twenty-one patients who underwent total knee arthroplasty due to osteoarthritis with involvement of the medial compartment but with minimum involvement of the lateral compartment were enrolled...
April 29, 2017: Clinical Rheumatology
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