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T2 mapping Imaging

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https://www.readbyqxmd.com/read/29774398/improved-detection-of-a-tumorous-involvement-of-the-mesorectal-fascia-and-locoregional-lymph-nodes-in-locally-advanced-rectal-cancer-using-dce-mri
#1
Marco Armbruster, Melvin D'Anastasi, Veronika Holzner, Martin E Kreis, Olaf Dietrich, Bernhard Brandlhuber, Anno Graser, Martina Brandlhuber
PURPOSE: The prediction of an infiltration of the mesorectal fascia (MRF) and malignant lymph nodes is essential for treatment planning and prognosis of patients with rectal cancer. The aim of this study was to assess the additional diagnostic value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) for the detection of a malignant involvement of the MRF and of mesorectal lymph nodes in patients with locally advanced rectal cancer. METHODS: In this prospective study, 22 patients with locally advanced rectal cancer were examined with 1...
May 17, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29772956/lumbar-muscle-structure-predicts-operational-postures-in-active-duty-marines
#2
David B Berry, Bahar Shahidi, Ana E Rodríguez-Soto, Jan M Hughes-Austin, Karen R Kelly, Samuel R Ward
Study Design Cross-sectional. Background The relationship between lumbar spine posture and muscle structure is not well understood. Objectives Investigate the predictive capacity of muscle structure on lumbar spine posture in active duty Marines. Methods Fouty-three Marines were scanned using an upright magnetic resonance imaging (MRI) scanner while standing unloaded and standing, sitting, and prone on elbows with body armor. Cobb, horizontal, and sacral angles were measured. Marines were then scanned unloaded in supine using a supine MRI scanner...
May 17, 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29770486/direct-estimation-of-17-o-mr-images-diesis-for-quantification-of-oxygen-metabolism-in-the-human-brain-with-partial-volume-correction
#3
Dmitry Kurzhunov, Robert Borowiak, Marco Reisert, Ali Caglar Özen, Michael Bock
PURPOSE: To provide a data post-processing method that corrects for partial volume effects (PVE) and fast T2* decay in dynamic 17 O MRI for the mapping of cerebral metabolic rates of oxygen consumption (CMRO2 ). METHODS: CMRO2 is altered in neurodegenerative diseases and tumors and can be measured after 17 O gas inhalation using dynamic 17 O MRI. CMRO2 quantification is difficult because of PVE. To correct for PVE, a direct estimation of the MR images (DIESIS) method is proposed and used in 4 dynamic 17 O MRI data sets of a healthy volunteer acquired on a 3T MRI system...
May 16, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29763672/using-3d-spatial-correlations-to-improve-the-noise-robustness-of-multi-component-analysis-of-3d-multi-echo-quantitative-t2-relaxometry-data
#4
Dushyant Kumar, Hari Hariharan, Tobias D Faizy, Patrick Borchert, Susanne Siemonsen, Jens Fiehler, Ravinder Reddy, Jan Sedlacik
PURPOSE: We present a computationally feasible and iterative multi-voxel spatially regularized algorithm for myelin water fraction (MWF) reconstruction. This method utilizes 3D spatial correlations present in anatomical/pathological tissues and underlying B1+ -inhomogeneity or flip angle inhomogeneity to enhance the noise robustness of the reconstruction while intrinsically accounting for stimulated echo contributions using T2-distribution data alone. METHODS: Simulated data and in vivo data acquired using 3D non-selective multi-echo spin echo (3DNS-MESE) were used to compare the reconstruction quality of the proposed approach against those of the popular algorithm (the method by Prasloski et al...
May 12, 2018: NeuroImage
https://www.readbyqxmd.com/read/29761595/radiomics-analysis-of-apparent-diffusion-coefficient-in-cervical-cancer-a-preliminary-study-on-histological-grade-evaluation
#5
Ying Liu, Yuwei Zhang, Runfen Cheng, Shichang Liu, Fangyuan Qu, Xiaoyu Yin, Qin Wang, Bohan Xiao, Zhaoxiang Ye
BACKGROUND: The role of apparent diffusion coefficient (ADC)-based radiomics features in evaluating histopathological grade of cervical cancer is unresolved. PURPOSE: To determine if there is a difference between radiomics features derived from center-slice 2D versus whole-tumor volumetric 3D for ADC measurements in patients with cervical cancer regarding tumor histopathological grade, and systematically assess the impact of the b value on radiomics analysis in ADC quantifications...
May 14, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29748204/a-qualitative-and-quantitative-correlation-study-of-lumbar-intervertebral-disc-degeneration-using-glycosaminoglycan-chemical-exchange-saturation-transfer-pfirrmann-grade-and-t1-%C3%AF
#6
O Togao, A Hiwatashi, T Wada, K Yamashita, K Kikuchi, C Tokunaga, J Keupp, M Yoneyama, H Honda
BACKGROUND AND PURPOSE: Glycosaminoglycan chemical exchange saturation transfer (gagCEST) imaging allows the direct measurement and mapping of glycosaminoglycans. In this study, we aimed to evaluate the usefulness of gagCEST imaging in the quantitative assessment of intervertebral disc degeneration in a comparison with Pfirrmann grade and T1-ρ measurements. MATERIALS AND METHODS: Ninety-six lumbar intervertebral discs in 24 volunteers (36.0 ± 8.5 years of age, 21 men and 3 women) were examined with both gagCEST imaging and T1-ρ measurements...
May 10, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29748200/extent-of-microstructural-tissue-damage-correlates-with-hemodynamic-failure-in-high-grade-carotid-occlusive-disease-an-mri-study-using-quantitative-t2-and-dsc-perfusion
#7
A Seiler, R Deichmann, U Nöth, A Lauer, W Pfeilschifter, O C Singer, M Wagner
BACKGROUND AND PURPOSE: Chronic hemodynamic impairment in high-grade carotid occlusive disease is thought to cause microstructural abnormalities that might be subclinical or lead to subtle symptoms including cognitive impairment. Quantitative MR imaging allows assessing pathologic structural changes beyond macroscopically visible tissue damage. In this study, high-resolution quantitative T2 mapping combined with DSC-based PWI was used to investigate quantitative T2 changes as a potential marker of microstructural damage in relation to hemodynamic impairment in patients with unilateral high-grade carotid occlusive disease...
May 10, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29744935/fast-magnetic-resonance-fingerprinting-for-dynamic-contrast-enhanced-studies-in-mice
#8
Yuning Gu, Charlie Y Wang, Christian E Anderson, Yuchi Liu, He Hu, Mette L Johansen, Dan Ma, Yun Jiang, Ciro Ramos-Estebanez, Susann Brady-Kalnay, Mark A Griswold, Chris A Flask, Xin Yu
PURPOSE: The goal of this study was to develop a fast MR fingerprinting (MRF) method for simultaneous T1 and T2 mapping in DCE-MRI studies in mice. METHODS: The MRF sequences based on balanced SSFP and fast imaging with steady-state precession were implemented and evaluated on a 7T preclinical scanner. The readout used a zeroth-moment-compensated variable-density spiral trajectory that fully sampled the entire k-space and the inner 10 × 10 k-space with 48 and 4 interleaves, respectively...
May 9, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29738908/rodent-cerebral-blood-volume-cbv-changes-during-hypercapnia-observed-using-magnetic-particle-imaging-mpi-detection
#9
Clarissa Zimmerman Cooley, Joseph B Mandeville, Erica E Mason, Emiri T Mandeville, Lawrence L Wald
Magnetic Particle Imaging (MPI) is a rapidly developing imaging modality that directly measures and maps the concentration of injected superparamagnetic iron oxide nanoparticles (SPIOs). Since the agent does not cross the blood-brain barrier, cerebral SPIO concentration provides a direct probe of Cerebral Blood Volume (CBV). Here we provide an initial demonstration of the ability of MPI to detect functional CBV changes (fCBV) by monitoring SPIO concentration during hypercapnic manipulation in a rat model. As a tracer detection method, MPI offers a more direct probe of agent concentration and therefore fCBV than MRI measurements in which the agent is indirectly detected through perturbation of water relaxation time constants such as T2 ∗ ...
May 5, 2018: NeuroImage
https://www.readbyqxmd.com/read/29734491/oxygenation-sensitive-cardiovascular-magnetic-resonance-in-hypertensive-heart-disease-with-left-ventricular-myocardial-hypertrophy-and-non-left-ventricular-myocardial-hypertrophy-insight-from-altered-mechanics-and-cardiac-bold-imaging
#10
Bing-Hua Chen, Rui Wu, Dong-Aolei An, Ruo-Yang Shi, Qiu-Ying Yao, Qing Lu, Jiani Hu, Meng Jiang, James Deen, Ankush Chandra, Jian-Rong Xu, Lian-Ming Wu
BACKGROUND: BOLD (blood oxygen level dependent) MRI can detect regional condition of myocardial oxygen supply and demand by means of paramagnetic properties. PURPOSE: Noninvasive assessment of myocardial oxygenation by BOLD MRI in hypertensive patients with hypertension (HTN) left ventricular myocardial hypertrophy (LVMH) and HTN non-LVMH and its correlation with myocardial mechanics were performed. STUDY TYPE: Prospective. POPULATION: Twenty patients with HTN LVMH, 21 patients with HTN non-LVMH, and 23 normotensive controls were enrolled...
May 7, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29734489/diagnostic-performance-of-intravoxel-incoherent-motion-diffusion-weighted-imaging-in-the-assessment-of-the-dynamic-status-of-myocardial-perfusion
#11
Dong-Aolei An, Bing-Hua Chen, Rui-Wu, Ruo-Yang Shi, Jun Bu, Heng Ge, Jiani Hu, Jian-Rong Xu, Lian-Ming Wu
BACKGROUND: Acute myocardial infarction (AMI) is a major cause of morbidity and mortality worldwide and places a significant financial burden on our society. PURPOSE: To determine the feasibility of cardiac intravoxel incoherent motion (IVIM) in the consecutive evaluation of myocardial perfusion in myocardial infarction patients postpercutaneous coronary intervention (PCI) and to investigate the dynamic biological phenomena in myocardial perfusion after AMI. STUDY TYPE: Prospective observational study...
May 7, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29734484/radiomic-features-from-pretreatment-biparametric-mri-predict-prostate-cancer-biochemical-recurrence-preliminary-findings
#12
Rakesh Shiradkar, Soumya Ghose, Ivan Jambor, Pekka Taimen, Otto Ettala, Andrei S Purysko, Anant Madabhushi
BACKGROUND: Radiomics or computer-extracted texture features derived from MRI have been shown to help quantitatively characterize prostate cancer (PCa). Radiomics have not been explored depth in the context of predicting biochemical recurrence (BCR) of PCa. PURPOSE: To identify a set of radiomic features derived from pretreatment biparametric MRI (bpMRI) that may be predictive of PCa BCR. STUDY TYPE: Retrospective. SUBJECTS: In all, 120 PCa patients from two institutions, I1 and I2 , partitioned into training set D1 (N = 70) from I1 and independent validation set D2 (N = 50) from I2 ...
May 7, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29733917/clinical-equivalence-assessment-of-t2-synthesized-pediatric-brain-magnetic-resonance-imaging
#13
Basile Kerleroux, Tobias Kober, Tom Hilbert, Maxence Serru, Dominique Sirinelli, Baptiste Morel
BACKGROUND AND PURPOSE: Automated synthetic magnetic resonance imaging (MRI) provides qualitative, weighted image contrasts as well as quantitative information from one scan and is well-suited for various applications such as analysis of white matter disorders. However, the synthesized contrasts have been poorly evaluated in pediatric applications. The purpose of this study was to compare the image quality of synthetic T2 to conventional turbo spin echo (TSE) T2 in pediatric brain MRI...
May 4, 2018: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/29731420/performance-of-t2-maps-in-the-detection-of-prostate-cancer
#14
Aritrick Chatterjee, Ajit Devaraj, Melvy Mathew, Teodora Szasz, Tatjana Antic, Gregory S Karczmar, Aytekin Oto
RATIONALE AND OBJECTIVES: This study compares the performance of T2 maps in the detection of prostate cancer (PCa) in comparison to T2-weighted (T2W) magnetic resonance images. MATERIALS AND METHODS: The prospective study was institutional review board approved. Consenting patients (n = 45) with histologic confirmed PCa underwent preoperative 3-T magnetic resonance imaging with or without endorectal coil. Two radiologists, working independently, marked regions of interests (ROIs) on PCa lesions separately on T2W images and T2 maps...
May 3, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29730991/feasibility-of-cardiovascular-magnetic-resonance-to-detect-oxygenation-deficits-in-patients-with-multi-vessel-coronary-artery-disease-triggered-by-breathing-maneuvers
#15
Kady Fischer, Kyohei Yamaji, Silvia Luescher, Yasushi Ueki, Bernd Jung, Hendrik von Tengg-Kobligk, Stephan Windecker, Matthias G Friedrich, Balthasar Eberle, Dominik P Guensch
BACKGROUND: Hyperventilation with a subsequent breath-hold has been successfully used as a non-pharmacological vasoactive stimulus to induce changes in myocardial oxygenation. The purpose of this pilot study was to assess if this maneuver is feasible in patients with multi-vessel coronary artery disease (CAD), and if it is effective at detecting coronary artery stenosis > 50% determined by quantitative coronary angiography (QCA). METHODS: Twenty-six patients with coronary artery stenosis (QCA > 50% diameter stenosis) underwent a contrast-free cardiovascular magnetic resonance (CMR) exam in the time interval between their primary coronary angiography and a subsequent percutaneous coronary intervention (PCI, n = 24) or coronary artery bypass (CABG, n = 2) revascularization procedure...
May 7, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29729437/influence-of-k-space-trajectory-corrections-on-proton-density-mapping-with-ultrashort-echo-time-imaging-application-for-imaging-of-short-t2-components-in-white-matter
#16
Peter Latta, Zenon Starčuk, Marco L H Gruwel, Barbora Lattova, Petra Lattova, Pavel Štourač, Boguslaw Tomanek
PURPOSE: To evaluate the impact of MR gradient system imperfections and limitations for the quantitative mapping of short T2* signals performed by ultrashort echo time (UTE) acquisition approach. MATERIALS AND METHODS: The measurement of short T2* signals from a phantom and a healthy volunteer study (8 subjects of average age 28 ± 4 years) were performed on a 3T scanner. The characteristics of the gradient system were obtained using calibration method performed directly on the measured subject or phantom...
May 2, 2018: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29725744/imaging-and-clinical-features-of-xanthogranulomatous-pancreatitis-an-analysis-of-10-cases-at-a-single-institution
#17
Ji Hye Kwon, Jin Hee Kim, So Yeon Kim, Jae Ho Byun, Hyoung Jung Kim, Seung-Mo Hong, Moon-Gyu Lee, Seung Soo Lee
PURPOSE: The purpose of the study was to investigate the imaging and clinical features of xanthogranulomatous pancreatitis (XGP). METHODS: This retrospective series study included 10 patients with pathology-proven XGP. Two radiologists reviewed the computed tomography (CT) and magnetic resonance imaging (MRI) in consensus to determine the morphological features of XGP. The lesion enhancement pattern on dynamic contrast-enhanced scans and the MR signal intensity were also evaluated...
May 3, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29717788/assessment-of-liver-ischemia-reperfusion-injury-in-mice-using-hepatic-t-2-mapping-comparison-with-histopathology
#18
Katja Hueper, Hannah Lang, Björn Hartleben, Marcel Gutberlet, Thorsten Derlin, Tobias Getzin, Rongjun Chen, Hassan Abou-Rebyeh, Frank Lehner, Martin Meier, Hermann Haller, Frank Wacker, Song Rong, Faikah Gueler
BACKGROUND: Liver ischemia reperfusion injury (IRI) occurs during liver surgery or transplantation resulting in an inflammatory response, tissue damage, and functional impairment of the organ. PURPOSE: To assess the feasibility of T2 mapping for noninvasive quantification of liver edema after partial liver IRI in mice. STUDY TYPE: Prospective, experimental study. ANIMAL MODEL: Partial liver IRI was induced in C57BL/6-mice by transient clamping of the left lateral and median liver lobes for 35 (n = 8), 45 (n = 6), 60 (n = 17), or 90 minutes (n = 5)...
May 2, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29713414/evaluation-of-lumbar-intervertebral-disc-degeneration-using-t1%C3%AF-and-t2-magnetic-resonance-imaging-in-a-rabbit-disc-injury-model
#19
Tetsuhiro Ishikawa, Atsuya Watanabe, Hiroto Kamoda, Masayuki Miyagi, Gen Inoue, Kazuhisa Takahashi, Seiji Ohtori
Study Design: An in vivo histologic and magnetic resonance imaging (MRI) study of lumbar intervertebral disc (IVD) degeneration was conducted. Purpose: To clarify the sensitivity and efficacy of T1ρ/T2 mapping for IVD degeneration, the correlation between T1ρ/T2 mapping and degenerative grades and histological findings in the lumbar IVD were investigated. Overview of Literature: The early signs of IVD degeneration are proteoglycan loss, dehydration, and collagen degradation...
April 2018: Asian Spine Journal
https://www.readbyqxmd.com/read/29708212/myocardial-tissue-characterization-by-combining-late-gadolinium-enhancement-imaging-and-percent-edema-mapping-a-novel-t2-map-based-mri-method-in-canine-myocardial-infarction
#20
Pal Suranyi, Gabriel A Elgavish, U Joseph Schoepf, Balazs Ruzsics, Pal Kiss, Marly van Assen, Brian E Jacobs, Brigitta C Brott, Ada Elgavish, Akos Varga-Szemes
Background: Assessing the extent of ischemic and reperfusion-associated myocardial injuries remains challenging with current magnetic resonance imaging (MRI) techniques. Our aim was to develop a tissue characterization mapping (TCM) technique by combining late gadolinium enhancement (LGE) with our novel percent edema mapping (PEM) approach to enable the classification of tissue represented by MRI voxels as healthy, myocardial edema (ME), necrosis, myocardial hemorrhage (MH), or scar. Methods: Six dogs underwent closed-chest myocardial infarct (MI) generation...
2018: European radiology experimental
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