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T2 mapping Imaging

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https://www.readbyqxmd.com/read/28715906/t2-mapping-provides-information-that-is-statistically-comparable-to-an-arthroscopic-evaluation-of-acetabular-cartilage
#1
Patrick Morgan, Mikko J Nissi, John Hughes, Shabnam Mortazavi, Jutta Ellerman
Objectives The purpose of this study was to validate T2* mapping as an objective, noninvasive method for the prediction of acetabular cartilage damage. Methods This is the second step in the validation of T2*. In a previous study, we established a quantitative predictive model for identifying and grading acetabular cartilage damage. In this study, the model was applied to a second cohort of 27 consecutive hips to validate the model. A clinical 3.0-T imaging protocol with T2* mapping was used. Acetabular regions of interest (ROI) were identified on magnetic resonance and graded using the previously established model...
July 1, 2017: Cartilage
https://www.readbyqxmd.com/read/28706185/deep-learning-for-fully-automated-localization-and-segmentation-of-rectal-cancer-on-multiparametric-mr
#2
Stefano Trebeschi, Joost J M van Griethuysen, Doenja M J Lambregts, Max J Lahaye, Chintan Parmer, Frans C H Bakers, Nicky H G M Peters, Regina G H Beets-Tan, Hugo J W L Aerts
Multiparametric Magnetic Resonance Imaging (MRI) can provide detailed information of the physical characteristics of rectum tumours. Several investigations suggest that volumetric analyses on anatomical and functional MRI contain clinically valuable information. However, manual delineation of tumours is a time consuming procedure, as it requires a high level of expertise. Here, we evaluate deep learning methods for automatic localization and segmentation of rectal cancers on multiparametric MR imaging. MRI scans (1...
July 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28704680/differentiating-parotid-tumors-by-quantitative-signal-intensity-evaluation-on-mr-imaging
#3
Eiji Matsusue, Yoshio Fujihara, Eiken Matsuda, Yusuke Tokuyasu, Shu Nakamoto, Kazuhiko Nakamura, Toshihide Ogawa
BACKGROUND: There have been no reports about quantitative evaluations of enhancing components of parotid tumors on conventional MR imaging. PURPOSE: To evaluate the signal intensity of the enhancing components of tumors, including pleomorphic adenomas (PAs), Warthin tumors (WTs) and malignant tumors (MTs), on various MR sequences and to assess the usefulness of quantitative evaluations for differentiation among the three groups of tumors. MATERIAL AND METHODS: A total of 39 histologically proven tumors, including 15 PAs, 17 WTs and 7 MTs, were enrolled in this study...
July 4, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28699215/automated-t2-relaxometry-of-the-hippocampus-for-temporal-lobe-epilepsy
#4
Gavin P Winston, Sjoerd B Vos, Jane L Burdett, M Jorge Cardoso, Sebastien Ourselin, John S Duncan
OBJECTIVE: Hippocampal sclerosis (HS), the most common cause of refractory temporal lobe epilepsy, is associated with hippocampal volume loss and increased T2 signal. These can be identified on quantitative imaging with hippocampal volumetry and T2 relaxometry. Although hippocampal segmentation for volumetry has been automated, T2 relaxometry currently involves subjective and time-consuming manual delineation of regions of interest. In this work, we develop and validate an automated technique for hippocampal T2 relaxometry...
July 12, 2017: Epilepsia
https://www.readbyqxmd.com/read/28694017/multi-frequency-interpolation-in-spiral-magnetic-resonance-fingerprinting-for-correction-of-off-resonance-blurring
#5
Jason Ostenson, Ryan K Robison, Nicholas R Zwart, E Brian Welch
Magnetic resonance fingerprinting (MRF) pulse sequences often employ spiral trajectories for data readout. Spiral k-space acquisitions are vulnerable to blurring in the spatial domain in the presence of static field off-resonance. This work describes a blurring correction algorithm for use in spiral MRF and demonstrates its effectiveness in phantom and in vivo experiments. Results show that image quality of T1 and T2 parametric maps is improved by application of this correction. This MRF correction has negligible effect on the concordance correlation coefficient and improves coefficient of variation in regions of off-resonance relative to uncorrected measurements...
July 7, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28693299/magnetic-resonance-imaging-characteristics-of-ischemic-brain-infarction-according-to-time-passage-in-a-canine-stroke-model
#6
Sooyoung Choi, Daji Noh, Youngwhan Kim, Inseong Jeong, Hojung Choi, Youngwon Lee, Kija Lee
This study describes magnetic resonance imaging findings and changes in lateral ventricular size according to time passage of canine ischemic stroke model. T1- and T2-weighted (T1W, T2W) imaging and fluid-attenuated inversion recovery (FLAIR) sequence were performed at 3 h and 3, 8, and 35 days after brain infarct induction. Diffusion-weighted imaging (DWI) and apparent diffusion coefficient mapping were obtained at 8 and 35 days. A total of 29 brain lesions were induced successfully in 12 of 14 beagle dogs...
July 10, 2017: Journal of Veterinary Science
https://www.readbyqxmd.com/read/28689257/fluid-attenuated-inversion-recovery-vascular-hyperintensities-in-predicting-cerebral-hyperperfusion-after-intracranial-arterial-stenting
#7
Chih-Cheng Wan, David Yen-Ting Chen, Ying-Chi Tseng, Feng-Xian Yan, Kun-Yu Lee, Chen-Hua Chiang, Chi-Jen Chen
PURPOSE: No reliable imaging sign predicting cerebral hyperperfusion after intracranial arterial stenting (IAS) had been described in the literature. This study evaluated the effect of fluid-attenuated inversion recovery vascular hyperintensities (FVHs), also called hyperintense vessel sign on T2-weighted fluid-attenuated inversion recovery (T2-FLAIR) MR images, in predicting significant increase in cerebral blood flow (CBF) defined by arterial spin labeling (ASL) after IAS. METHODS: We reviewed ASL CBF images and T2-FLAIR MR images before (D0), 1 day after (D1), and 3 days after (D3) IAS of 16 patients...
July 8, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28688198/study-of-the-interactions-between-proximal-femur-3d-bone-shape-cartilage-health-and-biomechanics-in-patients-with-hip-osteoarthritis
#8
Valentina Pedoia, Michael A Samaan, Gaurav Inamdar, Matthew C Gallo, Richard B Souza, Sharmila Majumdar
In this study quantitative MRI and gait analysis were used to investigate the relationships between proximal femur 3D bone shape, cartilage morphology, cartilage biochemical composition, and joint biomechanics in subject with hip Osteoarthritis (OA). Eighty subjects underwent unilateral hip MR-imaging: T1ρ and T2 relaxation times were extracted through voxel based relaxometry and bone shape was assessed with 3D MRI-based statistical shape modeling. In addition, 3D gait analysis was performed in seventy-six of the studied subjects...
July 8, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28685430/influence-of-free-radicals-on-the-intrinsic-mri-relaxation-properties
#9
Rong-Wen Tain, Alessandro M Scotti, Weiguo Li, Xiaohong Joe Zhou, Kejia Cai
Free radicals are critical contributors in various conditions including normal aging, Alzheimer's disease, cancer, and diabetes. Currently there is no non-invasive approach to image tissue free radicals based on endogenous contrast due to their extremely short lifetimes and low in vivo concentrations. In this study we aim at characterizing the influence of free radicals on the MRI relaxation properties. Phantoms containing free radicals were created by treating egg white with various H 2 O 2 concentrations and scanned on a 9...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28678672/acute-versus-chronic-myocardial-infarction-diagnostic-accuracy-of-quantitative-native-t1-and-t2-mapping-versus-assessment-of-edema-on-standard-t2-weighted-cardiovascular-mr-images-for-differentiation
#10
Enver Tahir, Martin Sinn, Sebastian Bohnen, Maxim Avanesov, Dennis Säring, Christian Stehning, Bernhard Schnackenburg, Christine Eulenburg, Joshua Wien, Ulf K Radunski, Stefan Blankenberg, Gerhard Adam, Charles B Higgins, Maythem Saeed, Kai Muellerleile, Gunnar K Lund
Purpose To analyze the diagnostic accuracy of native T1 and T2 mapping compared with visual and quantitative assessment of edema on T2-weighted cardiac magnetic resonance (MR) images to differentiate between acute and chronic myocardial infarction. Materials and Methods This study had institutional ethics committee approval. Written informed consent was obtained from 67 consecutive patients (57 years ± 12; 78% men) with a first acute myocardial infarction, who were prospectively enrolled between April 2011 and June 2015...
July 3, 2017: Radiology
https://www.readbyqxmd.com/read/28678410/simultaneous-mr-quantification-of-hepatic-fat-content-fatty-acid-composition-transverse-relaxation-time-and-magnetic-susceptibility-for-the-diagnosis-of-non-alcoholic-steatohepatitis
#11
B Leporq, S A Lambert, M Ronot, V Vilgrain, B E Van Beers
Non-alcoholic steatohepatitis (NASH) is characterized at histology by steatosis, hepatocyte ballooning and inflammatory infiltrates, with or without fibrosis. Although diamagnetic material in fibrosis and inflammation can be detected with quantitative susceptibility imaging, fatty acid composition changes in NASH relative to simple steatosis have also been reported. Therefore, our aim was to develop a single magnetic resonance (MR) acquisition and post-processing scheme for the diagnosis of steatohepatitis by the simultaneous quantification of hepatic fat content, fatty acid composition, T2 * transverse relaxation time and magnetic susceptibility in patients with non-alcoholic fatty liver disease...
July 5, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28676061/hemorrhage-promotes-inflammation-and-myocardial-damage-following-acute-myocardial-infarction-insights-from-a-novel-preclinical-model-and-cardiovascular-magnetic-resonance
#12
Nilesh R Ghugre, Mihaela Pop, Reuben Thomas, Susan Newbigging, Xiuling Qi, Jennifer Barry, Bradley H Strauss, Graham A Wright
BACKGROUND: Myocardial hemorrhage is a frequent complication following reperfusion in acute myocardial infarction and is predictive of adverse outcomes. However, it remains unsettled whether hemorrhage is simply a marker of a severe initial ischemic insult or directly contributes to downstream myocardial damage. Our objective was to evaluate the contribution of hemorrhage towards inflammation, microvascular obstruction and infarct size in a novel porcine model of hemorrhagic myocardial infarction using cardiovascular magnetic resonance (CMR)...
July 4, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28674085/acute-infarct-extracellular-volume-mapping-to-quantify-myocardial-area-at-risk-and-chronic-infarct-size-on-cardiovascular-magnetic-resonance-imaging
#13
Pankaj Garg, David A Broadbent, Peter P Swoboda, James R J Foley, Graham J Fent, Tarique A Musa, David P Ripley, Bara Erhayiem, Laura E Dobson, Adam K McDiarmid, Philip Haaf, Ananth Kidambi, Rob J van der Geest, John P Greenwood, Sven Plein
BACKGROUND: Late gadolinium enhancement (LGE) imaging overestimates acute infarct size. The main aim of this study was to investigate whether acute extracellular volume (ECV) maps can reliably quantify myocardial area at risk (AAR) and final infarct size (IS). METHODS AND RESULTS: Fifty patients underwent cardiovascular magnetic resonance imaging acutely (24-72 hours) and at convalescence (3 months). The cardiovascular magnetic resonance protocol included cines, T2-weighted imaging, native T1 maps, 15-minute post-contrast T1 maps, and LGE...
July 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28673762/diffusion-weighted-mri-in-image-guided-adaptive-brachytherapy-tumor-delineation-feasibility-study-and-comparison-with-gec-estro-guidelines
#14
Antoine Schernberg, Corinne Balleyguier, Isabelle Dumas, Sébastien Gouy, Alexandre Escande, Enrica Bentivegna, Philippe Morice, Eric Deutsch, Christine Haie-Meder, Cyrus Chargari
PURPOSE: To examine the feasibility of using diffusion-weighted images (DWIs) coregistered with T2-weighted (T2w) sequence in treatment planning system to improve target delineation for image-guided adaptive brachytherapy (IGABT) in locally advanced cervical cancer patients. METHODS AND MATERIALS: We retrospectively examined the records of consecutive patients who were referred to our institution for pulse-dose-rate IGABT between May and December 2015 after concurrent chemoradiation...
June 30, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28670163/t2-mapping-from-multi-echo-dixon-sequence-on-gadoxetic-acid-enhanced-magnetic-resonance-imaging-for-the-hepatic-fat-quantification-can-it-be-used-for-hepatic-function-assessment
#15
Hyunsuk Yoo, Jeong Min Lee, Jeong Hee Yoon, Hyo-Jin Kang, Sang Min Lee, Hyun Kyung Yang, Joon Koo Han
OBJECTIVE: To evaluate the diagnostic value of T2(*) mapping using 3D multi-echo Dixon gradient echo acquisition on gadoxetic acid-enhanced liver magnetic resonance imaging (MRI) as a tool to evaluate hepatic function. MATERIALS AND METHODS: This retrospective study was approved by the IRB and the requirement of informed consent was waived. 242 patients who underwent liver MRIs, including 3D multi-echo Dixon fast gradient-recalled echo (GRE) sequence at 3T, before and after administration of gadoxetic acid, were included...
July 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28669058/improved-neuroimaging-atlas-of-the-dentate-nucleus
#16
Naying He, Jason Langley, Daniel E Huddleston, Huawei Ling, Hongmin Xu, Chunlei Liu, Fuhua Yan, Xiaoping P Hu
The dentate nucleus (DN) of the cerebellum is the major output nucleus of the cerebellum and is rich in iron. Quantitative susceptibility mapping (QSM) provides better iron-sensitive MRI contrast to delineate the boundary of the DN than either T2-weighted images or susceptibility-weighted images. Prior DN atlases used T2-weighted or susceptibility-weighted images to create DN atlases. Here, we employ QSM images to develop an improved dentate nucleus atlas for use in imaging studies. The DN was segmented in QSM images from 38 healthy volunteers...
July 1, 2017: Cerebellum
https://www.readbyqxmd.com/read/28663515/noninvasive-assessment-of-oxygen-extraction-fraction-in-chronic-ischemia-using-quantitative-susceptibility-mapping-at-7-tesla
#17
Ikuko Uwano, Kohsuke Kudo, Ryota Sato, Kuniaki Ogasawara, Hiroyuki Kameda, Jun-Ichi Nomura, Futoshi Mori, Fumio Yamashita, Kenji Ito, Kunihiro Yoshioka, Makoto Sasaki
BACKGROUND AND PURPOSE: The oxygen extraction fraction (OEF) is an effective metric to evaluate metabolic reserve in chronic ischemia. However, OEF is considered to be accurately measured only when using positron emission tomography (PET). Thus, we investigated whether OEF maps generated by magnetic resonance quantitative susceptibility mapping (QSM) at 7 Tesla enabled detection of OEF changes when compared with those obtained with PET. METHODS: Forty-one patients with chronic stenosis/occlusion of the unilateral internal carotid artery or middle cerebral artery were examined using 7 Tesla-MRI and PET scanners...
June 29, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28661904/cardiac-sarcoidosis-challenges-in-clinical-practice
#18
Anne L Bakker, Jan C Grutters, Ruth G Keijsers, Martijn C Post
PURPOSE OF REVIEW: To address the current recommendations for screening, diagnosis, and treatment of cardiac sarcoidosis and the difficulties to put these recommendations into clinical practice. RECENT FINDINGS: The incidence of cardiac sarcoidosis appears to be higher than earlier reported, probably because of improved imaging techniques. Late gadolinium enhancement with cardiac MRI (LGE-CMR) and fluorodeoxyglucose positron emission tomography obtained a central role in the diagnostic algorithm and monitoring of disease activity...
June 28, 2017: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/28660946/janus-plasmonic-magnetic-gold-iron-oxide-nanoparticles-as-contrast-agents-for-multimodal-imaging
#19
Javier Reguera, Dorleta Jiménez de Aberasturi, Malou Henriksen-Lacey, Judith Langer, Ana Espinosa, Boguslaw Szczupak, Claire Wilhelm, Luis M Liz-Marzán
The design of compact nanoprobes for multimodal bioimaging is a current challenge and may have a major impact on diagnostics and therapeutics. Multicomponent gold-iron oxide nanoparticles have shown high potential as contrast agents in numerous imaging techniques due to the complementary features of iron oxide and gold nanomaterials. In this paper we describe novel gold-iron oxide Janus magnetic-plasmonic nanoparticles as versatile nanoprobes for multimodal imaging. The nanoparticles are characterized as contrast agents for different imaging techniques, including X-ray computed tomography (CT), T2-weighted nuclear magnetic resonance imaging (MRI), photoacoustic imaging (PA), dark-field and bright-field optical microscopy, transmission electron microscopy (TEM), and surface enhanced Raman spectroscopy (SERS)...
July 13, 2017: Nanoscale
https://www.readbyqxmd.com/read/28660142/clinical-application-of-concentrated-bone-marrow-aspirate-in-orthopaedics-a-systematic-review
#20
Arianna L Gianakos, Li Sun, Jay N Patel, Donald M Adams, Frank A Liporace
AIM: To examine the evidence behind the use of concentrated bone marrow aspirate (cBMA) in cartilage, bone, and tendon repair; establish proof of concept for the use of cBMA in these biologic environments; and provide the level and quality of evidence substantiating the use of cBMA in the clinical setting. METHODS: We conducted a systematic review according to PRISMA guidelines. EMBASE, MEDLINE, and Web of Knowledge databases were screened for the use of cBMA in the repair of cartilage, bone, and tendon repair...
June 18, 2017: World Journal of Orthopedics
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