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Tongue Pathology

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https://www.readbyqxmd.com/read/29667148/sublingual-nodules-diagnostic-markers-of-metastatic-breast-cancer
#1
Xue Yang, Cui-Hong Zhu, Rui Cao, Jian Hao, Xiong-Zhi Wu
OBJECTIVE: To evaluate the diagnostic significance of sublingual nodules for metastasis of patients with breast cancer and further to explore the mechanisms of sublingual nodules. METHODS: The image data of 117 in-patients with breast cancer in stage I-IV in Tianjin Medical University Cancer Institute and Hospital from December 2009 to September 2011 were assessed retrospectively. All photos of patients' tongue were recorded by the digital camera of uniform type within 1 month after serological examination and regular re-examined by computed tomography (CT), magnetic resonance imaging and positron emission tomography CT...
April 17, 2018: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29663518/potentially-malignant-disorders-revisited-the-lichenoid-lesion-proliferative-verrucous-leukoplakia-conundrum
#2
P J Thomson, M L Goodson, D R Smith
BACKGROUND: Clinically identifiable potentially malignant disorders (PMD) precede oral squamous cell carcinoma development. Oral lichenoid lesions (OLL) and proliferative verrucous leukoplakia (PVL) are specific precursor lesions believed to exhibit both treatment resistance and a high risk of malignant transformation (MT). METHODS: A retrospective review of 590 PMD patients treated in Northern England by CO2 laser surgery between 1996 and 2014 was carried out. Lesions exhibiting lichenoid or proliferative verrucous features were identified from the patient database and their clinico-pathological features and outcome post-treatment determined at the study census date of 31 December 2014...
April 16, 2018: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/29624713/clinical-and-imaging-hallmarks-of-the-myh7-related-myopathy-with-severe-axial-involvement
#3
Ivana Dabaj, Robert Y Carlier, David Gómez-Andrés, Osório Abath Neto, Enrico Bertini, Adele D'Amico, Fabiana Fattori, Yann Péréon, Claudia Castiglioni, Eliana Rodillo, Michela Catteruccia, Júlio Brandão Guimarães, Acary Souza Bulle Oliveira, Umbertina Conti Reed, Lilia Mesrob, Doris Lechner, Anne Boland, Jean-François Deleuze, Edoardo Malfatti, Carsten Bonnemann, Jocelyn Laporte, Norma Romero, Adrien Felter, Susana Quijano-Roy, Cristiane Araújo Martins Moreno, Edmar Zanoteli
INTRODUCTION: MYH7 gene mutations are related to a heterogeneous group of skeletal and cardiac myopathies. METHODS: We evaluated clinical and muscle magnetic resonance imaging changes in patients with mutations in the rod domain of MYH7 including one with mosaicism and three with novel missense mutations. RESULTS: Patients presented in childhood with a distal and axial phenotype. Biopsy findings were variable. Half of the cases displaying some type of core pathology, including minicores and eccentric cores...
April 6, 2018: Muscle & Nerve
https://www.readbyqxmd.com/read/29619557/performance-and-skill-retention-of-five-supraglottic-airway-devices-for-the-pediatric-difficult-airway-in-a-manikin
#4
Johannes Kulnig, Lisa Füreder, Nicole Harrison, Michael Frass, Oliver Robak
Supraglottic airway devices (SADs) have been introduced to assist medical professionals in emergency situations with limited experience in securing airways via conventional endotracheal intubation (ETI). Literature on the use of SADs for securing an airway during pediatric critical settings is scarce, and there is a lack of studies comparing different SADs to each other and to conventional ETI. We conducted a study comparing five different SADs to ETI with regard to success rate, time to first ventilation, and personal rating in a pediatric manikin under simulated physiologic and pathologic airway conditions in 41 pediatricians of varying clinical experience and training...
April 5, 2018: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29565472/a-novel-universal-device-lingual-ring-ri-p-a-ra-for-tmds-and-cranio-cervico-mandibular-pains-preliminary-results-of-a-randomized-control-clinical-trial
#5
A Rampello, P Papi, G Pompa, A Rampello, A Polimeni, C Di Paolo
OBJECTIVE: The aim of this study was to evaluate functionality and clinical application of a novel immediate device in the treatment of temporomandibular disorders (TMDs). To address the research purpose, authors developed and implemented a randomized control clinical trial. PATIENTS AND METHODS: Eighty patients were enrolled in this study and were randomly divided into two subgroups based on the treatment applied: patient group (PG) and control group (CG). The CG was not subjected to any kind of treatment, even placebo, in order to be able to assess the spontaneous development of the pathology over time...
March 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29563730/clinicopathological-factors-of-cervical-nodal-metastasis-and-the-concept-of-selective-lateral-neck-dissection-in-the-surgical-management-of-carcinoma-larynx-and-hypopharynx-and-its-outcome
#6
Elizabeth Mathew Iype, Santhosh Kumar N, Sreekanth S Kumar, Bipin T Varghese, Jaya C Jose
To study the clinicopathological and molecular factors which correlate with nodal metastasis in laryngeal and hypopharyngeal carcinoma, a retrospective analysis of 170 patients who underwent surgery for laryngeal and hypopharyngeal carcinoma at RCC, Trivandrum from 2006 to 2010 was done. The pathological nodal stage and levels of involvement were correlated with the clinicopathologic features of the primary disease. Neck node positivity was significantly more for lesions of pyriform sinus lesion (61%), with thyroid cartilage erosion (56%) and with base tongue involvement (88%)...
March 2018: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29563729/operable-oral-tongue-squamous-cell-cancer-15-years-experience-at-a-tertiary-care-center-in-north-india
#7
Nootan Kumar Shukla, S V Suryanarayana Deo, Pankaj Kumar Garg, N M L Manjunath, Suman Bhaskar, V Sreenivas
The aim of the present study was to provide insight into various demographic, clinical, and management profile of Indian patients with oral tongue squamous cell cancer (OTSCC). All the OTSCC patients who had undergone surgical treatment during 1995 to 2010 at a tertiary care center in North India were considered for the present study. The details of the patients were retrieved from a prospectively maintained computerized database. A total of 124 patients were included in the present study. Mean age of the patients was 50...
March 2018: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29556165/clinico-pathologic-review-of-biopsied-tongue-lesions-in-a-nigerian-tertiary-hospital
#8
T J Lasisi, T A Abimbola
Background: Varying pathologic conditions can affect the tongue for which the pattern of occurrence may differ. The aim of this study was to review the clinico-pathologic features of histologically diagnosed cases of tongue lesions that presented in our hospital over a 21 years period. Materials and Methods: Data on habits, class of lesion, histological diagnosis, age, gender, and site distributions were analyzed using descriptive frequencies, ranges and means ± SD...
December 2017: Annals of Ibadan Postgraduate Medicine
https://www.readbyqxmd.com/read/29520625/oro-dental-pathologies-in-acromegaly
#9
Ilonka Kreitschmann-Andermahr, Johannes Kohlmann, Bernadette Kleist, Ursula Hirschfelder, Rolf Buslei, Michael Buchfelder, Sonja Siegel
PURPOSE: Oro-dental pathologies (ODP) such as enlargement of the tongue, mandibular prognathism, and spaced teeth are characteristic features of acromegaly. Their frequency of occurrence during the course of the disease is largely unresolved. Purpose of this study was to assess ODP and oro-dental treatments in patients with acromegaly with regard to the length of the diagnostic process, tumor histology, and quality of life (QoL). METHODS: Single-center retrospective survey study using questionnaires on dental symptoms, diagnostic process, and treatment in patients with acromegaly operated on a growth hormone-secreting pituitary adenoma...
March 8, 2018: Endocrine
https://www.readbyqxmd.com/read/29513872/prevalence-of-communication-swallowing-and-orofacial-myofunctional-disorders-in-children-and-adolescents-at-the-time-of-admission-at-a-cancer-hospital
#10
Kaliani Lima Coça, Anke Bergmann, Sima Ferman, Elisabete Carrara de Angelis, Márcia Gonçalves Ribeiro
PURPOSE: Describe the prevalence of communication, swallowing and orofacial myofunctional disorders in a group of children and adolescents at the time of registration at a cancer hospital. METHODS: A cross-sectional study conducted with children aged ≥2 and adolescents, of both genders, admitted to the Pediatric Oncology Section of the Instituto Nacional de Câncer José de Alencar Gomes da Silva (INCA) from March 2014 to April 2015 for investigation and/or treatment of solid tumors...
March 1, 2018: CoDAS
https://www.readbyqxmd.com/read/29500569/a-pathological-study-of-the-tongues-of-rabid-dogs-in-the-philippines
#11
Nozomi Shiwa, Kazunori Kimitsuki, Daria Llenaresas Manalo, Satoshi Inoue, Chun-Ho Park
During rabies virus infections, the minor salivary glands are one of the important organs for virus replication and excretion into the oral cavity. However, details of pathological findings and viral antigen distribution in the minor salivary glands remain poorly understood. In this study, we conducted pathological tests on the tongues of 71 rabid dogs in the Philippines; the minor salivary glands (von Ebner's glands, lingual glands), circumvallate papilla, autonomic ganglia, and skeletal muscles were evaluated...
March 2, 2018: Archives of Virology
https://www.readbyqxmd.com/read/29494307/recurrent-spindle-cell-carcinoma-shows-features-of-mesenchymal-stem-cells
#12
T Ouchi, S Morikawa, S Shibata, M Takahashi, M Yoshikawa, T Soma, H Miyashita, W Muraoka, K Kameyama, H Kawana, Y Arima, H Saya, H Okano, T Nakagawa, S Asoda
This study investigated a case of spindle cell carcinoma (SpCC) in tongue pathological lesions. The patient experienced a local recurrence and distant metastasis after surgical intervention. Although standard chemotherapy was administered, a granulomatous mass continued to develop. This aggressive growth led to survival of the tumor. Secondary debulking surgery was performed to improve the patient's quality of life at the request of the patient. Using a tissue sample derived from the secondary debulking surgery, we performed an analysis of the tumor's cell surface antigens, differentiation potential, metastatic ability, and inhibition potential by anticancer reagents...
February 1, 2018: Journal of Dental Research
https://www.readbyqxmd.com/read/29490007/associations-between-human-fungiform-papillae-and-responsiveness-to-oral-stimuli-effects-of-individual-variability-population-characteristics-and-methods-for-papillae-quantification
#13
Maria Piochi, Caterina Dinnella, John Prescott, Erminio Monteleone
Fungiform papillae on human tongue are the proxy structures designated to oral stimuli detection and transduction. However, the role of their density (fungiform papillae/cm2) in explaining oral sensitivity is still controversial. While early studies generally found that the responsiveness to oral stimuli increased as the number of papillae increased, recent large-scale studies failed to confirm this finding.The present paper reviews relevant studies dealing with the relationship between fungiform papillae density and responsiveness to oral sensations including: fundamental tastes, 6-n-propyl-2-thiouracil (PROP) and sensations from trigeminal stimulation...
February 27, 2018: Chemical Senses
https://www.readbyqxmd.com/read/29480863/tongue-diagnosis-indices-for-upper-gastrointestinal-disorders-protocol-for-a-cross-sectional-case-controlled-observational-study
#14
Tzu-Chan Wu, Keng-Liang Wu, Wen-Long Hu, Jer-Ming Sheen, Cheng-Nan Lu, John Y Chiang, Yu-Chiang Hung
BACKGROUND: Upper gastrointestinal disorders are common in clinical practice, for example, gastritis, peptic ulcer disease, and gastroesophageal reflux disease. Panendoscopy or upper gastrointestinal endoscopy is viewed as the primary tool for examining the upper gastrointestinal mucosa, and permitting biopsy and endoscopic therapy. Although panendoscopy is considered to be a safe procedure with minimal complications, there are still some adverse effects, and patients are often anxious about undergoing invasive procedures...
January 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29469076/quality-of-life-outcome-measures-using-university-of-washington-questionnaire-version-4-in-early-t1-t2-anterior-tongue-cancers-with-and-without-radiotherapy-a-cross-sectional-study
#15
P Sakthivel, D V K Irugu, C A Singh, H Verma, R Yogal, B Jat, A Chadran, K Sikka, A Thakar, S C Sharma
CONTEXT: To evaluate the quality of life (QOL) outcome measures in disease-free survivors of pathological T1/T2 tongue cancers and to compare QOL in patients treated with only surgery and with adjuvant treatment. SETTINGS AND DESIGN: Cross-sectional survey. PATIENTS AND METHODS: All pathological T1/T2 anterior tongue cancer cases with follow-up from January 2011 till December 2015, who had locoregionally controlled disease with a minimum disease-free survival period of 1 year, were included in the study...
April 2017: Indian Journal of Cancer
https://www.readbyqxmd.com/read/29469075/paralingual-and-sublingual-space-invasion-in-magnetic-resonance-imaging-of-squamous-cell-carcinoma-of-anterior-two-thirds-of-tongue-is-there-a-prognostic-significance-a-prospective-evaluation
#16
S C Jayasankaran, P G Chelakkot, K Thankappan, S Iyer, S Moorthy
BACKGROUND: Magnetic resonance imaging (MRI) in tumors of anterior two-thirds of tongue has a significant role in assessing different tumor parameters, and in prognosticating. AIM: This prospective study conducted in a tertiary cancer care center, focused on patients with squamous cell carcinoma of anterior two-thirds of tongue. The significance of invasion of paralingual and sublingual spaces in relation to the pathological grade of these tumors, and its predictive value in pathological nodal involvement were analyzed...
April 2017: Indian Journal of Cancer
https://www.readbyqxmd.com/read/29452069/idiopathic-isolated-unilateral-hypoglossal-nerve-palsy-a-report-of-2-cases-and-review-of-the-literature
#17
Akio Shibata, Masashi Kimura, Kenichiro Ishiabashi, Masahiro Umemura
Hypoglossal nerve palsy (HNP) is a common finding in neurologic diseases when associated with other cranial nerve palsies or further pathology and exhibits characteristic clinical manifestations, including unilateral atrophy of the musculature of the tongue. It occasionally appears as the initial or solitary sign of an intracranial or extracranial space-occupying lesion, head or neck injury, or vascular abnormality of the internal carotid artery. There are few cases of idiopathic isolated unilateral HNP, which should be diagnosed through exclusion...
February 2, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29433184/transoral-versus-transnasal-approach-for-craniovertebral-junction-pathologies-never-say-never
#18
Massimiliano Visocchi, Francesco Signorelli, Chenlong Liao, Mario Rigante, Gaetano Paludetti, Giuseppe Barbagallo, Alessandro Olivi
OBJECTIVE: For many years, the microsurgical transoral approach (TOA) has been accepted as the "gold standard" for the surgical treatment of a variety of congenital, developmental, and acquired pathologies affecting the craniovertebral junction. In the present study, we try to investigate both experimental and clinical fronts of such a challenging surgery, starting from the updated literature experience. TOA is actually presented as an "old-fashioned" surgical technique dealing with possible bacterial contamination, the need of postoperative nose gastric tube feeding for a week, the possible nasopharyngeal incompetence, and the postoperative tongue swelling...
February 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29427291/prognostic-impact-of-tumour-stroma-ratio-in-early-stage-oral-tongue-cancers
#19
Alhadi Almangush, Ilkka Heikkinen, Nassira Bakhti, Laura K Mäkinen, Joonas H Kauppila, Matti Pukkila, Jaana Hagström, Jussi Laranne, Ylermi Soini, Luiz P Kowalski, Reidar Grénman, Caj Haglund, Antti A Mäkitie, Ricardo D Coletta, Ilmo Leivo, Tuula Salo
AIMS: Oral tongue squamous cell carcinoma (OTSCC) has a relatively poor outcome, and there is a need to identify better prognostic factors. Recently, tumour-stroma ratio (TSR) has been associated with prognosis in several cancers. The aim of this multi-institutional study was to evaluate the prognostic value of TSR from original haematoxylin and eosin (HE)-stained tumour-resection slides in a series of early-stage (cT1-2N0) OTSCC patients. METHODS AND RESULTS: A TSR cutoff value of 50% was used to divide the patients into stroma-rich (≥50%) and stroma-poor (<50%) groups...
February 10, 2018: Histopathology
https://www.readbyqxmd.com/read/29410763/oral-peripheral-nerve-sheath-tumors-a-clinicopathological-and-immunohistochemical-study-of-32-cases-in-a-brazilian-population
#20
Talita Franco, Silas-Antonio-Juvencio de Freitas Filho, Laís-Borges Muniz, Paulo-Rogério de Faria, Adriano-Mota Loyola, Sérgio-Vitorino Cardoso
Background: Oral peripheral nerve sheath tumors (OPNSTs) are reactive or neoplastic diseases that develop from proliferation of the nerve itself or their limiting sheaths. Here we describe the clinicopathologic data of OPNSTs observed in a sample of the Brazilian population and evaluate the expression of molecules associated with neural biology to determine their usefulness in the diagnosis. Material and Methods: Descriptive study of cases diagnosed as OPNSTs, from the Pathology Laboratory at the School of Dentistry/ Federal University of Uberlandia, followed by an immunohistochemical study of S-100, CD57, neurofilament protein (NFP) and epithelial membrane antigen (EMA)...
December 2017: Journal of Clinical and Experimental Dentistry
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