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Tongue Pathology

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https://www.readbyqxmd.com/read/28628162/-distant-metastases-of-malignant-salivary-gland-carcinoma-after-treated-by-125-i
#1
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OBJECTIVE: To investigate clinical features of distant metastases from malignant salivary gland carcinomas after treated by (125)I internal brachy therapy alone. METHODS: Between 2002 and 2010, 43 patients with locally advanced unresectable or recurrent malignant salivary gland carcinomas were treated by (125)I internal brachy therapy alone at Peking University School and Hospital of Stomatology. All of them had been follow-up at least 2 years. The primary sites of malignant salivary gland carcinomas were the parotid for 12 patients, infratemporal fossa for 9 patients, tongue for 7 patients, maxilla for 6 patients, parapharyngeal for 4 patients, floor of months for 3 patients, submandibular gland for 1 patient, and lip for 1 patient...
June 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28625010/treatment-of-tongue-base-masses-in-children-by-transoral-robotic-surgery
#2
Fatma Tulin Kayhan, Ayse Pelin Yigider, Arzu Karaman Koc, Kamil Hakan Kaya, Ibrahim Erdim
The feasibility and effectiveness of transoral robotic surgery (TORS) in children with tongue base masses (TBMs) were evaluated. Eight pediatric patients who were treated with TORS for TBMs between January 2010 and January 2016 at a tertiary hospital included in the study. All pathologies were congenital lesions: four were lingual thyroglossal ductus cysts (LTGDCs), one was a minor salivary gland tumor, one was a vallecular cyst, one was a bronchogenic cyst, and one was an ectopic thyroid tissue. TORS was performed successfully in all cases...
June 17, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28619152/the-newly-emerging-duck-origin-goose-parvovirus-in-china-exhibits-a-wide-range-of-pathogenicity-to-main-domesticated-waterfowl
#3
Shifeng Xiao, Shilong Chen, Xiaoxia Cheng, Fengqiang Lin, Shao Wang, Xiaoli Zhu, Bo Yu, Meiqing Huang, Jinxiang Wang, Nanyang Wu, Min Zheng, Shaoying Chen, Fusong Yu
Short beak and dwarfism syndrome virus (SBDSV) is a newly emerging distinct duck-origin goose parvovirus that belongs to the genus Dependovirus. Our previous studies have found that SBDSV was highly pathogenic to Cherry Valley ducklings and mule ducklings. However, little is known about its pathogenicity to other waterfowls. In the present study, the pathogenicity of SBDSV was evaluated in domesticated waterfowl including Muscovy ducklings, Sheldrake ducklings and domestic goslings. All experimentally infected birds exhibited remarkable growth retardation, anorexia and diarrhea similar to naturally infected birds...
May 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28614209/newly-described-entities-in-salivary-gland-pathology
#4
Alena Skálová, Douglas R Gnepp, James S Lewis, Jennifer L Hunt, Justin A Bishop, Henrik Hellquist, Alessandra Rinaldo, Vincent Vander Poorten, Alfio Ferlito
Salivary glands may give rise to a wide spectrum of different tumors. This review concentrates on 4 salivary gland tumors that have been accepted in the recent literature as new neoplastic entities: mammary analog secretory carcinoma, cribriform adenocarcinoma of minor salivary glands (CASG), sclerosing polycystic adenosis/adenoma (SPA), and the mucinous/secretory variant of myoepithelioma. Mammary analog secretory carcinoma is a distinctive low-grade malignant salivary cancer that harbors a characteristic chromosomal translocation, t(12;15) (p13;q25), resulting in an ETV6-NTRK3 fusion...
June 13, 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28610739/histologic-and-immunohistochemical-identification-of-cribriform-adenocarcinoma
#5
Rashidah Wiley, Aditya Kalgi, Renee Reich, Paul Freedman
OBJECTIVE: To assess whether tumors originally classified as adenocarcinoma not otherwise specified (Adca-NOS), adenoid cystic carcinoma (ACC), and polymorphous low-grade adenocarcinoma (PLGA) could be reclassified as cribriform adenocarcinoma of the tongue and minor salivary gland (CATMSG). STUDY DESIGN: Tumors diagnosed between 1992 and 2014 at Oral Pathology Laboratory, Inc. (New York Presbyterian Hospital) were selected. Each tumor was reviewed by 3 oral pathologists to confirm the diagnosis of CATMSG...
July 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28606298/-melkersson-rosenthal-syndrome-in-a-young-man
#6
Elisabeth Lauritzen, Andreas P Schjellerup Jørkov
A 24-year-old man presented with orofacial swelling, peripheral facial palsy and fissured tongue. Apart from a previous episode of peripheral palsy, he had no history of illness. Biopsy of the lip, blood tests, magnetic resonance imaging of the head and lumbar puncture showed no pathology. He received systemic prednisone for ten days, and follow-up showed sparse improvement in facial movements. The patient could have been misdiagnosed with Bell's palsy, but the symptoms rather indicated a case of Melkersson-Rosenthal syndrome...
June 12, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28603602/a-rare-case-of-perianal-granular-cell-tumor-case-report-and-literature-review
#7
Emily F Kelly, Alan A Stein, Xiaoling Charlene Ma, Jose Yeguez
Granular cell tumor (GCT) is a rare submucosal neoplasm most commonly localized in the oral mucosa; with one-third of all cases found in the tongue, with less than 30 cases of perianal GCT reported in the literature, making it a rare anal neoplasm. Wide local excision is the gold standard of treatment and follow-up includes annual colonoscopy due to the high incidence of reoccurrence. Here we describe a rare case of benign perianal GCT in a 29-year-old female who presented asymptomatically; however, pathology report revealed a S100 positive immunostaining pattern...
June 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28576543/pycnodysostosis-at-otorhinolaryngology
#8
Tekin Baglam, Adem Binnetoglu, Muhammet Fatih Topuz, Nilay Baş Ikizoglu, Refika Ersu, Serap Turan, Murat Sarı
AIM: Pycnodysostosis is a rare autosomal, recessive, skeletal dysplasia caused by a mutation in the cathepsin k gene. Pycnodysostosis is characterized by short stature, characteristic facial appearance (delayed closure of fontanelles and cranial sutures, mandibular hypoplasia and angle disorder, blue sclera), and acroosteolysis of the distal phalanges. Our aim was to describe the otorhinolaryngologic findings, differential diagnoses, various treatment options, and followup in eight cases of pycnodysostosis...
April 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28570699/vimentin-is-a-potential-prognostic-factor-for-tongue-squamous-cell-carcinoma-among-five-epithelial-mesenchymal-transition-related-proteins
#9
Pei-Feng Liu, Bor-Hwang Kang, Yi-Min Wu, Ju-Hsin Sun, Liang-Ming Yen, Ting-Ying Fu, Yun-Chung Lin, Huei-Han Liou, Yaoh-Shiang Lin, Huei-Cin Sie, I-Chien Hsieh, Yu-Kai Tseng, Chih-Wen Shu, Yao-Dung Hsieh, Luo-Ping Ger
We aimed to investigate the association of the expression levels of five epithelial-mesenchymal transition (EMT)-related proteins (Snail, Twist, E-cadherin, N-cadherin, and Vimentin) with tumorigenesis, pathologic parameters and prognosis in tongue squamous cell carcinoma (TSCC) patients by immunohistochemistry of tissue microarray. The expression levels of Snail, E-cadherin, N-cadherin and Vimentin were significantly different between the tumor adjacent normal and tumor tissues. In tumor tissues, lower E-cadherin and higher N-cadherin levels were associated with a higher grade of cell differentiation, advanced stage of disease, and lymph node metastasis...
2017: PloS One
https://www.readbyqxmd.com/read/28547793/the-anatomy-and-physiology-of-normal-and-abnormal-swallowing-in-oropharyngeal-dysphagia
#10
REVIEW
A Sasegbon, S Hamdy
BACKGROUND: Eating and drinking are enjoyable activities that positively impact on an individual's quality of life. The ability to swallow food and fluid is integral to the process of eating. Swallowing occupies a dual role being both part of the enjoyment of eating and being a critically important utilitarian activity to enable adequate nutrition and hydration. Any impairment to the process of swallowing can negatively affect a person's perception of their quality of life. The process of swallowing is highly complex and involves muscles in the mouth, pharynx, larynx, and esophagus...
May 25, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28529103/the-importance-of-lymph-node-ratio-for-locoregional-recurrence-of%C3%A2-squamous-cell-carcinoma-of-the-tongue
#11
Ali-Farid Safi, Andrea Grandoch, Hans-Joachim Nickenig, Joachim E Zöller, Matthias Kreppel
INTRODUCTION: Locoregional recurrence plays a key role in treatment failure of patients with squamous cell carcinoma of the tongue. In a large amount of studies lymph node ratio could be demonstrated as a promising parameter to stratify risk of patients with oral cavity cancer. However data on the influence of lymph node ratio on locoregional recurrence of tongue squamous cell carcinoma is very rare. MATERIAL AND METHODS: Retrospective chart review of 130 patients with treatment naive squamous cell carcinoma of the tongue...
April 22, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28528293/spatiotemporal-movement-variability-in-als-speaking-rate-effects-on-tongue-lower-lip-and-jaw-motor-control
#12
Mili Kuruvilla-Dugdale, Antje Mefferd
PURPOSE: Although it is frequently presumed that bulbar muscle degeneration in Amyotrophic Lateral Sclerosis (ALS) is associated with progressive loss of speech motor control, empirical evidence is limited. Furthermore, because speaking rate slows with disease progression and rate manipulations are used to improve intelligibility in ALS, this study sought to (i) determine between and within-group differences in articulatory motor control as a result of speaking rate changes and (ii) identify the strength of association between articulatory motor control and speech impairment severity...
May 2017: Journal of Communication Disorders
https://www.readbyqxmd.com/read/28517962/inhibition-of-the-continuum-of-radiation-induced-normal-tissue-injury-by-a-redox-active-mn-porphyrin
#13
Samuel R Birer, Chen-Ting Lee, Kingshuk Roy Choudhury, Kenneth H Young, Ivan Spasojevic, Ines Batinic-Haberle, James D Crapo, Mark W Dewhirst, Kathleen A Ashcraft
Normal tissue damage after head and neck radiotherapy involves a continuum of pathologic events to the mucosa, tongue and salivary glands. We examined the radioprotective effects of MnBuOE, a redox-active manganese porphyrin, at three stages of normal tissue damage: immediate (leukocyte endothelial cell [L/E] interactions), early (mucositis) and late (xerostomia and fibrosis) after treatment. In this study, mice received 0 or 9 Gy irradiation to the oral cavity and salivary glands ± MnBuOE treatment. Changes in leukocyte-endothelial cell interactions were measured 24 h postirradiation...
May 18, 2017: Radiation Research
https://www.readbyqxmd.com/read/28509514/lay-public-s-use-of-a-support-group-for-general-dental-problems
#14
K K Walker, R D Jackson
OBJECTIVE: To categorize and tabulate layperson inquiries made to an Internet dental health support site to identify oral conditions and associated behaviors of concern. METHODS: A retrospective tabulation of wall postings was made from an established dental health support website hosted by WebMD over a 2-year period (April 2013-April 2015). A mixed method approach of content and thematic analysis was used. Content analysis identified content of oral health concerns, while thematic analysis using grounded theory identified themes and beliefs concerning associated behaviors...
September 2016: Community Dental Health
https://www.readbyqxmd.com/read/28504503/-cervicofacial-actinomycosis-as-differential-diagnosis-of-cavum-carcinoma-case-report
#15
Eliana T Anteliz García, Carolina M Carballo, Samanta Estévez, Sofía Diana, Arturo de Mena, Gabriela Manonelles, Claudia I Cazes, Eduardo L López
Paediatric actinomycosis is an infrequent infectious disease caused by Actinomyces spp. Cervicofacial infections are usually related to disruption in oral mucosal membranes. We discuss the case of a 15-year-old girl who refers an 8-month history of odynophagia and changes in her tone of voice after getting a tongue piercing. She received multiple antibiotic treatments with slight improvement. Nasopharyngeal carcinoma was diagnosed by endoscopic biopsy. The patient was referred to our Hospital for treatment but, when the biopsy was analyzed again, oncological pathology was excluded and oropharyngeal actinomycosis was diagnosed...
June 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28485346/squamous-cell-carcinoma-of-the-upper-aerodigestive-tract-in-exclusive-smokers-chewers-and-those-with-no-habits
#16
S Nair, S Datta, S Thiagarajan, S Chakrabarti, D Nair, P Chaturvedi
BACKGROUND: Tobacco consumption is the major risk factor for developing head and neck squamous cell cancer (SCC). The site of development of HNSCC may depend on the way the tobacco is consumed. While laryngeal cancers are more common among smokers, oral cancers are more common among tobacco chewers. Since the use of smokeless tobacco is increasing, it is important to know whether this difference is restricted only to site wise distribution or it has other clinical and pathological implications...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28484837/what-should-we-expect-from-robotic-surgery-for-second-primary-oropharyngeal-cancer
#17
Tuan-Jen Fang, Li-Ang Lee, Bing-Shan Huang, Chien-Yu Lin, Cheng-Lung Hsu, Joseph Tung-Chieh Chang, Tzu-Chen Yen, Chun-Ta Liao, Hui-Chen Chiang
The outcomes of second primary oropharyngeal cancer (SPOPC) may not be determined by oropharyngeal cancer but from the other index cancer as well. The management of (SPOPC) remains inconclusive and limited. Transoral robotic surgery (TORS) to maximize the functional outcomes without reducing oncologic effect is suggested as the primary treatment for selected oropharyngeal cancer. This study aimed to evaluate the feasibility and outcomes of TORS for the management of SPOPC. Patients who underwent TORS from January 2011 to June 2015 at a tertian referral center in Taiwan were recruited...
May 9, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28483472/neck-failure-after-elective-neck-dissection-in-patients-with-oral-squamous-cell-carcinoma
#18
Hiroaki Shimamoto, Yu Oikawa, Toshimitsu Osako, Hideaki Hirai, Yumi Mochizuki, Kae Tanaka, Hirofumi Tomioka, Hiroyuki Harada
OBJECTIVE: Analysis of the incidence and clinical relevance of neck failure after elective neck dissection (END) in patients with oral squamous cell carcinoma (OSCC). STUDY DESIGN: A retrospective study of 188 patients with OSCC without cervical lymph node metastases was conducted; these patients had undergone END from 2005 to 2015. The most common primary tumor location was lower gingiva, followed by tongue. RESULTS: Supraomohyoid neck dissection (SOHND) was the most common procedure...
March 10, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28479702/inflammatory-myofibroblastic-tumor-of-mandible-a-rare-case-report-and-review-of-literature
#19
Rajani Korlepara, Venkateswara Rao Guttikonda, Jayakiran Madala, Sravya Taneeru
Inflammatory pseudotumor is a term given to different neoplastic and nonneoplastic entities that have a common histological appearance, which comprises spindle cell proliferation with a prominent chronic inflammatory cell infiltrate. Inflammatory myofibroblastic tumor (IMT) is an uncommon lesion with distinctive clinical, pathological and molecular features and is considered to be pseudotumor for the past two decades due to its appearance. IMT is an intermediate soft tissue tumor which was first observed in lungs...
January 2017: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/28470695/sublethal-oligodendrocyte-injury-a-reversible-condition-in-multiple-sclerosis
#20
Qiao-Ling Cui, Damla Khan, Malena Rone, Vijayaraghava T S Rao, Radia Marie Johnson, Yun Hsuan Lin, Philippe-Antoine Bilodeau, Jeffery A Hall, Moses Rodriguez, Timothy E Kennedy, Samuel K Ludwin, Jack P Antel
OBJECTIVE: Degeneration of oligodendroglial distal processes has been identified as an early event in multiple sclerosis (MS) lesion development. Our objective was to further define the development of the "dying-back" oligodendrocyte lesion in situ and to model the development and potential reversibility of such responses using dissociated cultures of adult human brain-derived oligodendrocytes. METHODS: In situ analyses were performed on glutaraldehyde-fixed thin sections of clinically acute and pathologically active cases of MS...
May 3, 2017: Annals of Neurology
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