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Thyroid disfunction

A F Caeiro, V Santos, G Dias, E Landim, I Santos, T Matos, A Nazaré
INTRODUCTION: Chronic Hypertension (CH) is one of the most prevalent diseases in the world. Because women are getting pregnant in late ages, the incidence of Chronic Hypertension in pregnancy is raising (2-3%). As a long term disease in its essential form, with low repercussion in target-organs at reproductive age, the medical complications related to CH are not the main concern of the pregnant women. However, it influences the pregnancy and may result in serious maternal-fetal complications, especially if a preeclampsia/eclampsia superimposes to pregnancy...
July 2012: Pregnancy Hypertension
Pilar Sierra, Rosa Cámara, Helena Tobella, Lorenzo Livianos
Thyroid disfunction affects negatively emotional stability and worsens the clinical course of bipolar affective disorder. The main stabilizer used in this illness, lithium carbonate has numerous effects on the physiology of the thyroid, with the most significant being the inhibition of thyroid hormone release that may occur at therapeutic levels. These dysfunctions have also been reported most frequently in bipolar patients not undergoing treatment with lithium, and was not completely explained by the effects of this drug...
April 2014: Revista de Psiquiatrí́a y Salud Mental
Claudio Terzano, S Romani, G Paone, V Conti, F Oriolo
BACKGROUND: Chronic obstructive pulmonary (COPD) is one of the major causes of morbidity and mortality in the world. COPD is characterized by chronic inflammation in the pulmonary compartment and in the systemic circulation. This disorder is associated with clinically significant alterations in biochemistry and organ function; thyroid dysfunctions are common in chronic diseases, such as COPD. Several characteristics of COPD patients could increase their likelihood of developing hypothyroidism or hyperthyroidism...
February 2014: Lung
Teresa Lorenzo Gómez, Federico Cardelle Pérez, Elena De Las Heras Liñero
INTRODUCTION: The relation of the neuroendocrine system with the psychiatric disorders has been described by different authors throughout history. OBJECTIVES: To evaluate the presence of thyroid disfunction in psychiatric inpatients. METHODS: Observacional, descriptive, retrospective study of all the psychiatric inpatients in the UHP of Vigo during the year 2006, in which the presence of thyroid dysfunction is evaluated immediately when they are admitted...
January 2010: Revista de Psiquiatrí́a y Salud Mental
Emina Kasumagic-Halilovic, Asja Prohic, Begler Begovic, Nermina Ovcina-Kurtovic
Background. Vitiligo is a common skin disorder characterized by macular depigmentation of the skin. The etiopathogenesis of the disease is still unclear, but there is evidence that autoimmunity and endocrine disfunction may be involved. Objective. The aim of this study was to determine whether vitiligo is statistically associated with thyroid autoimmunity. Method. In a prospective case-control study, we compared the frequency of thyroid autoantibodies (thyroglobulin antibody, anti-Tg and thyroid peroxidase antibody, and anti-TPO) in 33 patients with vitiligo and in 33 healthy volunteers...
2011: Journal of Thyroid Research
G A Jahn, G Moya, H Jammes, R R Rosato
We studied the effect on cycling, ovulation and hormone secretion of a chronic thyroxine treatment (HT, 1 mg/kg,S.C., daily, initiated at oestrus) on female rats. HT rats showed normal 4-day vaginal cycles on the first three cycles after initiation of the treatment, but on the fourth cycle had a prolonged oestrus and subsequently entered in constant di-oestrus. In spite of the normal vaginal cycles only 66%, 50%, 33% and 10% of the HT rats ovulated on cycles 1 to 4 respectively. In contrast, during cycles 2 and 3, ovulating HT rats shed a significantly greater number of ova than controls...
February 1995: Endocrine
M Maggiolini, G De Luca, M Bria, D Sisci, S Aquila, V Pezzi, M Lanzino, A Giorno, O Tamburrini, M Della Sala, E Corcioni, C Brancati, S Ando
The aim of our investigation was to evaluate thyroid function by a follow-up study in 45 polytransfused thalassemic patients, since endocrine abnormalities are frequent consequences of iron overload in thalassemia major. Significant changes of thyroid function have been revealed in the time elapsing the observation, despite unchanged haematological parameters; at the end of the present study five patients were affected by overt hypothyroidism and 15 patients by subclinical hypothyroidism. Ultrasound thyroid volume in 13 randomly selected patients was greatly reduced, while thyroid Magnetic Resonance Imaging (MRI) was not able to detect tissue alterations...
February 1995: Endocrine
Aleksandra Nikolić, Dragan Micić, Dejan Nikolić, Violeta Stanimirović
INTRODUCTION: In more than 50 years since the first demonstration of the immune basis for thyroiditis was done, the autoimmune disease has been identified as a major cause of disfunction of all endocrine organs. Identification of the antithyroid with the radioreceptor assay is widespread in clinical use for differential diagnosis of other thyroid disorders manifesting with the hyperthyroidism. MATERIAL AND METHODS: Our study included 44 patients with new onset Graves disease which was primarily verified according to the objective status of the patients (signs of hyperthyroidism), biochemical parameters (which included thyroid hormones) and detection of the TRAb (TSAb- thyreotropin-stimulating antibodies) at the beginning of diagnosis and in the first, second and after the third month since the introduction of antithyroid therapy (propiltiouracil)...
July 2009: Medicinski Pregled
M L Tanda, V Lombardi, M Genovesi, F Ultimieri, A Lai, M Gandolfo, I Dalle Mule, L Grasso, F Bogazzi, F Broglio, E Ghigo, E Martino, L Bartalena
BACKGROUND: Results of circulating Ghrelin levels in hyper- or hypothyroidism are conflicting and only overt thyroid dysfunction has been evaluated. AIM: To evaluate in a large number of patients with thyroid disfunction whether: a) hyper- and hypothyroidism (clinical or subclinical) are associated with variations in both acylated (AG) and total Ghrelin (TG) concentrations, and b) correction of thyroid dysfunction is followed by variations in Ghrelin concentrations...
January 2009: Journal of Endocrinological Investigation
A Uchikov, B Nonchev, V Danev, K Murdzhev, S Vladeva, D Terzieva
OBJECTIVE: The aim of this study was to evaluate the results of the surgical treatment of patients with thyrotoxicosis in three surgical clinics in Plovdiv. PATIENTS AND MEDHOTS: We studied 90 patients, who underwent surgical treatment for thyrotoxicosis between 2000-2004. Of those 19 men (21%) and 71 women (79%); men:women = 1:3.74; mean age 38 +/- 8.3 years. The nosological distribution was as follows: Graves' disease--72 subjects (80.00%), solitary toxic adenoma--4 subjects (4.40%), toxic nodular goiter--14 subjects (15...
2006: Khirurgiia
N B Kvirkveliia, R R Shakarishvili, N N Lobzhanidze
On the basis of clinical-EMG analyses, the researches have revealed the criteria characteristic of myasthenia associated with thyroid pathologies. The myasthenia process associated with thyroid pathology is mainly characterized as of generalized average intensity. Alongside with mup-s with reduced duration and amplitude characteristic of myasthenia, EMG exposes potentials with comparatively long duration and high amplitude (mainly when the process is associated with thyreotoxycosis). It should also be noted that spontaneous activity is intensively expressed...
July 2008: Georgian Medical News
Mario Andreoli
This review focuses on the mechanisms by which thyroid hormones affect the regulation of the cardiovascular system and the thermogenic and hemodynamic variation induced by thyroid disfunction. It is also stressed the hormonal role of the cardiac myocytes realising natriuretic peptides, involved in plasma volume homeostasis and cardiovascular remodelling; its rapid measurement is a useful clinical tool, in the diagnostic and prognostic of left ventricular dysfunction, correlating with the degree of the clinical symptoms...
December 2006: Recenti Progressi in Medicina
Patrícia Grativol Costa, Fábio Petersen Saraiva, Suzana Matayoshi
INTRODUCTION: Botulinum toxin is an alternative treatment for retraction of ocular thyroid related dysfunction. The aim of this study was to evaluate the effects of this medication on upper lid position, levator palpebrae superioris muscle function and corneal exposure. METHODS: Seven patients were enrolled into the study. The palpebral fissure images were acquired by a digital camera and transferred to a computer video edition program in order to be processed and analyzed...
October 2006: Arquivos Brasileiros de Endocrinologia e Metabologia
G Cavallaro, A Polistena, F Fornari, M Ruperto, C Letizia, G De Toma
Amyloid goiter is a rare pathology due to massive amyloid infiltration of thyroid tissue, which cause diffuse or localized enlargement of the gland. It can be totally asymptomatic or cause only non-specific symptoms (compression of adjacent structures, tracheal deviation). Thyroid disfunction (hypothyroidism or hyperthyroidism) is rare. It is important to differentiate primitive amyloid goiter from other kinds of amyloid infiltration of the thyroid, such as in systemic amyloidosis. The correct diagnosis can be difficult because of the common presence of amyloid in thyroid neoplasms, such as medullary thyroid carcinoma (MTC)...
August 2006: Il Giornale di Chirurgia
A Neves Mascarenhas, C Papadia, C Alves Aquino, L Oba, M Ferreira, L A Casulari
AIM: The treatment of acute lymphoblastic leukemia (ALL) in children may cause sequelae, some appearing only at long-term follow-up. We investigated the thyroid gland morphology and the function of the pituitary-thyroid axis in a group of patients treated for ALL in childhood. METHODS: A cohort study was conducted at a tertiary medical center. Thirty-three children (22 males and 11 females; age: 11.9+/-3 years; range: 6 to 18 years) were studied. The mean age at the time of chemotherapy and prophylactic cranial irradiation (12-24 Gy) was 5...
October 2006: Minerva Pediatrica
I I Dedov, G A Mel'nichenko, N Iu Sviridenko, N M Platonova, N V Molashenko, A V Egorov
The authors of the study investigated the effects of pharmacological doses of iodine as an ingredient of amiodaron, an anti-arrhythmic agent, and iodine radiopaque contrast agents (RCA), on the thyroid gland (TG) function. The subjects were 133 patients aged 60.5 +/- 8.5 years, who had been taking amiodaron for 12 to 164 months, and 164 patients aged 59.4 +/- 9.1 years, who were examined before coronarography (CAG) with RCA, and 1, 3, 6, and 12 months after the procedure. Serum levels of TSH, FT4, FT3, TG antibodies, TPO antibodies, and urine iodine level were measured; TG ultrasonography was performed...
2006: Vestnik Rossiĭskoĭ Akademii Meditsinskikh Nauk
Massimo Bindi, Massimiliano Pinelli, Javier Rosada, Maido Castiglioni
Many diseases can lead to atrial fibrillation and one of these is thyroid disfunction. The prevalence of atrial fibrillation does not differ between subclinical and overt hyperthyroidism. Hypothyroidism also can be associated to atrial fibrillation. Low-T3 syndrome is considered a risk factor in cardiac patients. In 100 patients affected by atrial fibrillation we studied the thyroid function and performed ultrasound examination of the thyroid gland. 30 patients had a low-T3 syndrome, 66 (38 > or =10 mm) patients had thyroid nodules, while just 10 patients had an abnormal thyroid function...
November 2005: Recenti Progressi in Medicina
Djunajdar Kerimović-Morina
Musculosceletal manifestations were found in patients with hyperthyroidism as well as hypothyroidism. This article will review the available evidence that autoimmune thyroid disease is associated with: Sjögren's sydrome (SS), systemic lupus erythematosus (SLE), systemic sclerosis, rheumatoid arthritis (RA) and spondyloarthropathies. Possible pathogenesis of these manifestations has not been completely established. Sjögren's syndrome occurs in about 1/10 of patients with autoimmune thyroid disease; patients with SLE and antithyroid antibodies were significantly older than those pattiens without antibodies...
October 2005: Srpski Arhiv za Celokupno Lekarstvo
Murat Suher, Eyup Koc, Naim Ata, Cuneyt Ensari
Fifty-eight patients with thyroid dysfunction were included, comparing 27 healthy subjects to evaluate the relationship between thyroid autoimmunity, thyroid functional status, and renal function. Regardless of clinical status, hypothyroidism was defined as T3-T4<normal limits and TSH>upper limit of normal, and hyperthyroidism was defined as T3-T4>normal limits and TSH <0.1 mcU/mL. In all participants, serum antithyroperoxidase level, serum antithyroglobulin level, creatinine clearance (CC), and urinary albumin excretion rate (UAER) in 24-h urine collections were measured...
2005: Renal Failure
Chiara Santori, Claudio Di Veroli, Francesca Di Lazzaro, Chiara Caliumi, Luigi Petramala, Dario Cotesta, Monica Iorio, Valentina Serra, Massimiliano Celi, Emilio D'Erasmo, Claudio Letizia
Primary hyperaldosteronism is associated with other endocrinology pathologies, like pheochromocytoma, Cushing's syndrome, hyperprolactinemia, primary hyperparathyroidism and a type of multiple endocrine neoplasia. Furthermore, association between hyperaldosteronism and thyroid diseases were already pointed out. Aim of the study was to value the prevalence of some thyroid diseases in a series of patients with primary hyperaldosteronism. We studied 105 consecutive patients with primary hyperaldosteronism, 43 (40...
July 2005: Recenti Progressi in Medicina
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