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bipolar type ii

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https://www.readbyqxmd.com/read/27855101/long-term-cost-effectiveness-of-collaborative-care-vs-usual-care-for-people-with-depression-and-comorbid-diabetes-or-cardiovascular-disease-a-markov-model-informed-by-the-coincide-randomised-controlled-trial
#1
Elizabeth M Camacho, Dionysios Ntais, Peter Coventry, Peter Bower, Karina Lovell, Carolyn Chew-Graham, Clare Baguley, Linda Gask, Chris Dickens, Linda M Davies
OBJECTIVES: To evaluate the long-term cost-effectiveness of collaborative care (vs usual care) for treating depression in patients with diabetes and/or coronary heart disease (CHD). SETTING: 36 primary care general practices in North West England. PARTICIPANTS: 387 participants completed baseline assessment (collaborative care: 191; usual care: 196) and full or partial 4-month follow-up data were captured for 350 (collaborative care: 170; usual care: 180)...
October 7, 2016: BMJ Open
https://www.readbyqxmd.com/read/27847590/interhemispheric-functional-disconnection-because-of-abnormal-corpus-callosum-integrity-in-bipolar-disorder-type-ii
#2
Fumihiko Yasuno, Takashi Kudo, Kiwamu Matsuoka, Akihide Yamamoto, Masato Takahashi, Jyoji Nakagawara, Kazuyuki Nagatsuka, Hidehiro Iida, Toshifumi Kishimoto
BACKGROUND: A significantly lower fractional anisotropy (FA) value has been shown in anterior parts of the corpus callosum in patients with bipolar disorder. AIMS: We investigated the association between abnormal corpus callosum integrity and interhemispheric functional connectivity (IFC) in patients with bipolar disorder. METHODS: We examined the association between FA values in the corpus callosum (CC-FA) and the IFC between homotopic regions in the anterior cortical structures of bipolar disorder (n=16) and major depressive disorder (n=22) patients with depressed or euthymic states...
November 2016: BJPsych Open
https://www.readbyqxmd.com/read/27846411/binge-eating-disorder-and-bipolar-spectrum-disorders-in-obesity-psychopathological-and-eating-behaviors-differences-according-to-comorbidities
#3
Cristina Segura-Garcia, Mariarita Caroleo, Marianna Rania, Elvira Barbuto, Flora Sinopoli, Matteo Aloi, Franco Arturi, Pasquale De Fazio
BACKGROUND: Obesity is not a mental disorder, yet DSM-5 recognizes a strong association between obesity and psychiatric syndromes. Disorders within the Bipolar Spectrum (BSD) and Binge Eating Disorder (BED) are the most frequent psychiatric disorders among obese patients. The aim of this research is to investigate the psychopathological differences and the distinctive eating behaviors that accompany these comorbidities in obese patients. METHODS: One hundred and nineteen obese patients (40 males; 79 females) underwent psychological evaluation and psychiatric interview, and a dietitian evaluated their eating habits...
November 10, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27813593/case-report-case-study-of-a-patient-presenting-both-type-ii-bipolar-affective-disorder-and-klinefelter-syndrome
#4
H Delavenne, J M Khoury, F Thibaut, F D Garcia
Klinefelter syndrome (KS) is the most common sex chromosomal disorder with an estimated prevalence of 1 in 500-1000. Increased incidences of anxiety, depression, substance abuse, psychotic and behavioral disorders, and sexual disorders have been reported in patients with KS. The aim of this case study was to report a case of a man with untreated KS who was also diagnosed with type II bipolar disorder. This case report raises awareness regarding psychiatric diagnoses that may be associated with such a highly prevalent condition...
October 17, 2016: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/27798713/shortened-telomere-length-in-bipolar-disorder-a-comparison-of-the-early-and-late-stages-of-disease
#5
Florencia M Barbé-Tuana, Mariana M Parisi, Bruna S Panizzutti, Gabriel R Fries, Lucas K Grun, Fátima T Guma, Flávio Kapczinski, Michael Berk, Clarissa S Gama, Adriane R Rosa
Objective: Bipolar disorder (BD) has been associated with increased rates of age-related diseases, such as type II diabetes, metabolic syndrome, osteoporosis, and cardiovascular disorders. Several biological findings have been associated with age-related disorders, including increased oxidative stress, inflammation, and telomere shortening. The objective of this study was to compare telomere length among participants with BD at early and late stages and age- and gender-matched healthy controls...
October 2016: Revista Brasileira de Psiquiatria
https://www.readbyqxmd.com/read/27734702/-psycho-immuno-endocrinology-of-the-thyroid-gland
#6
Ivan Šterzl, Karolína Absolonová, Petr Matucha
Historically endocrinologists and psychiatrists are aware that disturbances in thyroid disease in beginning or even in clinically intensified states of thyrotoxicosis or hypothyroidism exhibit pathological mental manifestations, masking or potentiating the underlying disease. Immune system disorders cause thyroid organ-specific autoimmune process. This autoimmune thyroid disease binds with a number of disorders in both endocrine or non-endocrine organs. This appears in vascular, neurological, skin, connective tissue, gastrointestinal tract and mental pathology...
2016: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/27733933/efficient-and-robust-ventricular-tachycardia-and-fibrillation-detection-method-for-wearable-cardiac-health-monitoring-devices
#7
Eedara Prabhakararao, M Sabarimalai Manikandan
In this Letter, the authors propose an efficient and robust method for automatically determining the VT and VF events in the electrocardiogram (ECG) signal. The proposed method consists of: (i) discrete cosine transform (DCT)-based noise suppression; (ii) addition of bipolar sequence of amplitudes with alternating polarity; (iii) zero-crossing rate (ZCR) estimation-based VTVF detection; and (iv) peak-to-peak interval (PPI) feature based VT/VF discrimination. The proposed method is evaluated using 18,000 episodes of different ECG arrhythmias taken from 6 PhysioNet databases...
September 2016: Healthcare Technology Letters
https://www.readbyqxmd.com/read/27663044/-metabolic-syndrome-and-bipolar-disorder-is-sleep-the-missing-link
#8
H Brochard, C Boudebesse, C Henry, O Godin, M Leboyer, B Étain
OBJECTIVE: To examine the pathophysiologic mechanisms that may link circadian disorder and metabolic syndrome in bipolar disorder (BP). METHOD: A systematic review of the literature was conducted from January 2013 to January 2015, using the Medline and Cochrane databases, using the keywords "metabolic syndrome", "obesity", "leptin" and "circadian disorders", "sleeping disorders" and cross-referencing them with "bipolar disorder". The following types of publications were candidates for review: (i) clinical trials; (ii) studies involving patients diagnosed with bipolar disorder; (iii) studies involving patients with sleeping disorder; or (iv) data about metabolic syndrome...
September 20, 2016: L'Encéphale
https://www.readbyqxmd.com/read/27647353/group-acceptance-and-commitment-therapy-act-for-bipolar-disorder-and-co-existing-anxiety-an-open-pilot-study
#9
Sara Pankowski, Mats Adler, Gerhard Andersson, Nils Lindefors, Cecilia Svanborg
Previous studies have supported acceptance and commitment therapy (ACT) for reducing impairment related to various chronic conditions. ACT may possibly be beneficial for bipolar disorder (BD) with co-existing anxiety, which is associated with a poorer treatment outcome. Efforts are needed to identify suitable psychological interventions for BD and co-existing anxiety. In this open clinical trial, we included 26 patients with BD type 1 or 2 at an outpatient psychiatric unit specializing in affective disorders...
September 19, 2016: Cognitive Behaviour Therapy
https://www.readbyqxmd.com/read/27644707/predictors-of-the-discrepancy-between-objective-and-subjective-cognition-in-bipolar-disorder-a-novel-methodology
#10
K W Miskowiak, J Z Petersen, C V Ott, U Knorr, L V Kessing, P Gallagher, L Robinson
OBJECTIVE: The poor relationship between subjective and objective cognitive impairment in bipolar disorder (BD) is well-established. However, beyond simple correlation, this has not been explored further using a methodology that quantifies the degree and direction of the discrepancy. This study aimed to develop such a methodology to explore clinical characteristics predictive of subjective-objective discrepancy in a large BD patient cohort. METHODS: Data from 109 remitted BD patients and 110 healthy controls were pooled from previous studies, including neuropsychological test scores, self-reported cognitive difficulties, and ratings of mood, stress, socio-occupational capacity, and quality of life...
December 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27638073/acute-unilateral-loss-of-vestibular-function
#11
M Fetter
Sudden unilateral loss of vestibular function is the most severe condition that can occur in the vestibular system. The clinical syndrome is caused by the physiologic properties of the vestibulo-ocular reflex (VOR) arc. In the normal situation, the two peripheral vestibular end organs are connected to a functional unit in coplanar pairs of semicircular canals working in a push-pull mode. "Push-pull" mode means that, when one side is excited, the other side is inhibited, and vice versa due to two mechanisms...
2016: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/27614042/phospholipid-protein-balance-in-affective-disorders-analysis-of-human-blood-serum-using-raman-and-ftir-spectroscopy-a-pilot-study
#12
Joanna Depciuch, Magdalena Sowa-Kućma, Gabriel Nowak, Dominika Dudek, Marcin Siwek, Krzysztof Styczeń, Magdalena Parlińska-Wojtan
Raman and FTIR (Fourier Transform Infra Red) spectroscopies provide information on the chemical structure of compounds through identification and analysis of functional groups. In the present study, both spectroscopic techniques were used for investigating the phospholipid - protein balance in blood serum of depressed subjects (major depressive disorder and bipolar disorder type I or II) taking also into account their age and gender. The obtained results were compared with those of healthy subjects. The Raman and FTIR (using ATR (Attenuated Total Reflectance) technique), spectra show that a correlation between the level of phospholipids and proteins exists...
November 30, 2016: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/27583247/diacylglycerol-kinases-as-emerging-potential-drug-targets-for-a-variety-of-diseases-an-update
#13
REVIEW
Fumio Sakane, Satoru Mizuno, Suguru Komenoi
Ten mammalian diacylglycerol kinase (DGK) isozymes (α-κ) have been identified to date. Our previous review noted that several DGK isozymes can serve as potential drug targets for cancer, epilepsy, autoimmunity, cardiac hypertrophy, hypertension and type II diabetes (Sakane et al., 2008). Since then, recent genome-wide association studies have implied several new possible relationships between DGK isozymes and diseases. For example, DGKθ and DGKκ have been suggested to be associated with susceptibility to Parkinson's disease and hypospadias, respectively...
2016: Frontiers in Cell and Developmental Biology
https://www.readbyqxmd.com/read/27576186/brain-hyper-excitability-revealed-by-optimal-electrical-stimulation-of-gabaergic-interneurons
#14
F Wendling, U Gerber, D Cosandier-Rimele, A Nica, J De Montigny, O Raineteau, S Kalitzin, F Lopes da Silva, P Benquet
BACKGROUND: Neurological disorders are often characterized by an excessive and prolonged imbalance between neural excitatory and inhibitory processes. An ubiquitous finding among these disorders is the disrupted function of inhibitory GABAergic interneurons. OBJECTIVE: The objective is to propose a novel stimulation procedure able to evaluate the efficacy of inhibition imposed by GABAergic interneurons onto pyramidal cells from evoked responses observed in local field potentials (LFPs)...
July 15, 2016: Brain Stimulation
https://www.readbyqxmd.com/read/27574265/relationship-between-pull-out-strength-and-oscillation-angle-in-bipolar-cups-an-in-vitro-study
#15
N Kaku, T Tabata, H Tsumura
PURPOSE: To compare the past and present bipolar hip arthroplasty (BHA) models in terms of balance between pull-out strength and oscillation angle (OA). METHODS: The pull-out strength and OA of 8 BHA models were compared: UPF-II, IBC, and Tandem XLPE (Smith & Nephew); Ringloc x (Biomet); J-FX (DePuy); Bipolar (Nakashima Medical); Multipolar (Zimmer); and Centrax (Stryker). RESULTS: Respectively for the UPF-II, IBC, Tandem, Ringloc, J-FX, Nakashima Bipolar, Multipolar, and Centrax, the mean pull-out strength was 2219 N, 3303 N, 1503 N, 951 N, 1453 N, 1856 N, 1536 N, and 753 N, whereas the mean OA was 54...
August 2016: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/27567184/progressive-focal-gray-matter-volume-loss-in-a-former-high-school-football-player-a-possible-magnetic-resonance-imaging-volumetric-signature-for-chronic-traumatic-encephalopathy
#16
Cyrus A Raji, David A Merrill, Jorge R Barrio, Bennet Omalu, Gary W Small
Here a case is presented of a 51-year-old former high school football player with multiple concussions, including one episode with loss of consciousness. The patient experienced 6 years of cognitive and mood decline, and his wife corroborated increasing memory loss, attentional difficulties, and depressed mood without suicidal ideation. He had been unable to maintain full-time employment because of progressive decline. Based on his presentation, he had been previously diagnosed with attention deficit hyperactivity disorder and bipolar disorder, type II...
October 2016: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/27559133/assembly-of-caenorhabditis-elegans-acentrosomal-spindles-occurs-without-evident-microtubule-organizing-centers-and-requires-microtubule-sorting-by-klp-18-kinesin-12-and-mesp-1
#17
Ian D Wolff, Michael V Tran, Timothy J Mullen, Anne M Villeneuve, Sarah M Wignall
Although centrosomes contribute to spindle formation in most cell types, oocytes of many species are acentrosomal and must organize spindles in their absence. Here we investigate this process in Caenorhabditis elegans, detailing how acentrosomal spindles form and revealing mechanisms required to establish bipolarity. Using high-resolution imaging, we find that in meiosis I, microtubules initially form a "cage-like" structure inside the disassembling nuclear envelope. This structure reorganizes so that minus ends are sorted to the periphery of the array, forming multiple nascent poles that then coalesce until bipolarity is achieved...
October 15, 2016: Molecular Biology of the Cell
https://www.readbyqxmd.com/read/27535187/a-case-of-lithium-intoxication-induced-by-an-antihypertensive-angiotensin-1-subtype-specific-angiotensin-ii-receptor-blocker-in-an-elderly-patient-with-bipolar-disorder-and-hypertension
#18
Yuichi Hayashi, Shohei Nishida, Akira Takekoshi, Muneharu Murakami, Megumi Yamada, Akio Kimura, Akio Suzuki, Takashi Inuzuka
Lithium carbonate is considered to be a first-line treatment for bipolar disorder; however, this drug has a narrow therapeutic window, and lithium intoxication is commonly induced by various drugs interaction and situations. We herein report a case of lithium intoxication induced by the administration of an antihypertensive agent targeting the angiotensin 1 (AT1) subtype of the angiotensin II receptor in a 65-year-old woman with a 40-year history of bipolar disorder type 1, and 1-year history of essential hypertension...
2016: Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
https://www.readbyqxmd.com/read/27525607/factors-related-to-treatment-compliance-in-bipolar-disorder
#19
Hichem Kassaoui, Saoussen Bouhlel, Jaafar Nakhli, Imen Ben Mahmoud, Selma Ben Nasr, Béchir Ben Hadj Ali
BACKGROUND: Medication non-adherence is a major problem in patients with bipolar disorder as it is associated to poor clinical outcomes with frequent relapses and consequently poor quality of life. The reasons that patients are non adherent with medication are not well understood by clinicians who often consider it as related to the illness itself.    AIMS: To assess sociodemographic, clinical and therapeutic factors related to medication compliance in bipolar disorder...
January 2016: La Tunisie Médicale
https://www.readbyqxmd.com/read/27521631/extensive-characterization-of-the-new-genus-rickiopora-polyporales
#20
Mauro C Westphalen, Mario Rajchenberg, Michal Tomšovský, Adriana M Gugliotta
Ceriporiopsis latemarginata and Antrodiella angulatopora are two Neotropical polypores that are very similar morphologically and are characterized by effused-reflexed basidiomes, large angular pores, small ellipsoid to ovoid basidiospores and a monomitic hyphal system with presence of thick-walled hyphae with infrequent clamps. In order to verify the evolutionary relations of C. latemarginata and to find its taxonomic placement, morphological, biological, and phylogenetic studies were carried out, as well as comparisons with Antrodiella s...
August 2016: Fungal Biology
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