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https://www.readbyqxmd.com/read/28715727/efficacy-and-safety-of-long-term-antidepressant-treatment-for-bipolar-disorders-a-meta-analysis-of-randomized-controlled-trials
#1
Bangshan Liu, Yan Zhang, Han Fang, Jin Liu, Tiebang Liu, Lingjiang Li
OBJECTIVE: Efficacy and safety of long-term use of antidepressants (AD) in bipolar disorder (BD) patients remains highly controversial. Here we performed a meta-analysis of randomized controlled trials (RCTs) exploring the efficacy and safety of long-term AD use in BD patients. METHODS: English-written literature published in peer-reviewed journal was systematically searched from Pubmed, EMBASE, CENTRAL, PsycINFO and Clinicaltrials.gov. Each database was searched from its first available time to August 31, 2016...
July 11, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28699182/amygdala-and-hippocampus-volumes-are-differently-affected-by-childhood-trauma-in-patients-with-bipolar-disorders-and-healthy-controls
#2
Delfina Janiri, Gabriele Sani, Pietro De Rossi, Fabrizio Piras, Mariangela Iorio, Nerisa Banaj, Giulia Giuseppin, Edoardo Spinazzola, Matteo Maggiora, Elisa Ambrosi, Alessio Simonetti, Gianfranco Spalletta
OBJECTIVES: Volumetric studies on deep gray matter structures in bipolar disorder (BP) have reported contrasting results. Childhood trauma, a relevant environmental stressor for BP, could account for the variability of the results, modulating differences in the amygdala and hippocampus in patients with BP compared with healthy controls (HC). Our study aimed to test this hypothesis. METHODS: We assessed 105 outpatients, diagnosed with bipolar disorder type I (BP-I) or bipolar disorder type II (BP-II) according to DSM-IV-TR criteria, and 113 HC subjects...
July 12, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/28684405/sleep-loss-as-a-trigger-of-mood-episodes-in-bipolar-disorder-individual-differences-based-on-diagnostic-subtype-and-gender
#3
Katie Swaden Lewis, Katherine Gordon-Smith, Liz Forty, Arianna Di Florio, Nick Craddock, Lisa Jones, Ian Jones
BackgroundSleep loss may trigger mood episodes in people with bipolar disorder but individual differences could influence vulnerability to this trigger.AimsTo determine whether bipolar subtype (bipolar disorder type I (BP-I) or II (BD-II)) and gender were associated with vulnerability to the sleep loss trigger.MethodDuring a semi-structured interview, 3140 individuals (68% women) with bipolar disorder (66% BD-I) reported whether sleep loss had triggered episodes of high or low mood. DSM-IV diagnosis of bipolar subtype was derived from case notes and interview data...
July 6, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28629452/inhibitory-brainstem-reflexes-under-external-emotional-stimuli-in-bipolar-i-and-ii-disorders
#4
Qisha Zhu, Jiawei Wang, Chanchan Shen, Hongying Fan, Bingren Zhang, Guorong Ma, Yanxia Lu, Wei Wang
BACKGROUND: Bipolar disorder types I (BD I) and II (BD II) might present different dysfunctions of the cortex and brainstem, as reflected by the second exteroceptive suppression period of temporalis muscle activity (ES2) under different stimuli of external emotions. METHODS: This study included 30 BD I and 20 BD II patients, and 40 healthy volunteers. All participants were invited to answer the Mood Disorder Questionnaire, the Hypomania Checklist-32, and the Plutchik-van Praag Depression inventory, as well as to undergo the ES2 test under external emotional-stimuli (emotional pictures plus sounds) of Disgust, Erotica, Fear, Happiness, and Sadness...
June 19, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28595099/circadian-rhythm-sleep-wake-disorders-as-predictors-for-bipolar-disorder-in-patients-with-remitted-mood-disorders
#5
Yoshikazu Takaesu, Yuichi Inoue, Kotaro Ono, Akiko Murakoshi, Kunihiro Futenma, Yoko Komada, Takeshi Inoue
BACKGROUND: Circadian rhythm dysfunction is thought to play a key role in the pathogenesis of bipolar disorder (BD). We focused on circadian rhythm sleep-wake disorders (CRSWD) as possible predictors for bipolar disorder in patients with remitted mood disorders. METHOD: One hundred four BD (41 type I and 63 type II) outpatients and 73 age- and sex-matched major depressive disorder (MDD) outpatients participated in this study. The subjects were asked to answer questionnaires including demographic variables, clinical course of the disorder, and family history of psychiatric disorders...
October 1, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28503106/depression-and-mania-in-bipolar-disorder
#6
Leonardo Tondo, Gustavo H Vázquez, Ross J Baldessarini
BACKGROUND: Episode duration, recurrence rates, and time spent in manic and depressive phases of bipolar disorder (BD) is not well defined for subtypes of the disorder. METHODS: We reviewed the course, timing, and duration of episodes of mania and depression among 1130 clinically treated DSM-IV-TR BD patients of various types, and compared duration and rates as well as total proportion of time in depressive versus manic episodes during 16.7 average years at risk...
April 2017: Current Neuropharmacology
https://www.readbyqxmd.com/read/28501741/executive-functioning-deficits-among-adults-with-bipolar-disorder-types-i-and-ii-a-systematic-review-and-meta-analysis
#7
REVIEW
Tania Dickinson, Rodrigo Becerra, Jacqui Coombes
BACKGROUND: Executive functioning (EF) deficits contribute to a significant proportion of the burden of disease associated with bipolar disorder (BD). Yet, there is still debate in the literature regarding the exact profile of executive functioning in BD. The purpose of the present project was to assess whether EF deficits exist among adults suffering BD, and whether these deficits (if apparent) differ by BD subtype. METHODS: A systematic search identified relevant literature...
April 29, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28474733/practitioner-review-the-effects-of-atypical-antipsychotics-and-mood-stabilisers-in-the-treatment-of-depressive-symptoms-in-paediatric-bipolar-disorder
#8
REVIEW
Tobias Atkin, Nicolas Nuñez, Gabriella Gobbi
BACKGROUND: The management of depressive and mixed symptoms in children and adolescents with bipolar disorder (BD) remains a matter of debate. The goal of this review is, thus, to systematically examine the impact of atypical antipsychotics (AAPs) and mood stabilisers in the treatment of bipolar depression and/or mixed states. METHODS: A literature search was conducted for studies assessing the efficacy of pharmacological treatments for bipolar disorder type I, type II and not otherwise specified with a recent depressive, mixed or manic episode (with depressive symptoms) following DSM-IV criteria in children and adolescents as either acute or maintenance treatment...
May 5, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28472082/efficacy-of-cognitive-behavioral-therapy-in-patients-with-bipolar-disorder-a-meta-analysis-of-randomized-controlled-trials
#9
Kai-Jo Chiang, Jui-Chen Tsai, Doresses Liu, Chueh-Ho Lin, Huei-Ling Chiu, Kuei-Ru Chou
BACKGROUND: Although cognitive behavioral therapy (CBT) is considered a promising adjuvant to pharmacotherapy for treating bipolar disorder (BD), its efficacy is unproven. The present review and meta-analysis evaluated the treatment outcomes of patients with BD treated with CBT plus medication and compared these data with the outcomes of those who received standard care alone. METHODS: Electronic searches from inception to July 31, 2016, were performed using PubMed, Medline OVID, Cochrane Library, EMBASE, CINAHL plus, and PsycINFO...
2017: PloS One
https://www.readbyqxmd.com/read/28437059/psychotic-and-bipolar-disorders-bipolar-disorder
#10
REVIEW
Sarah D Holder
Bipolar disorder is a severe chronic mental illness that affects a large number of individuals. This disorder is separated into two major types, bipolar I disorder, with mania and typically recurrent depression, and bipolar II disorder, with recurrent major depression and hypomania. Patients with bipolar disorder spend the majority of time experiencing depression, and this typically is the presenting symptom. Because outcomes are improved with earlier diagnosis and treatment, physicians should maintain a high index of suspicion for bipolar disorder...
April 2017: FP Essentials
https://www.readbyqxmd.com/read/28399092/-the-affective-pathology-in-patients-with-adolescent-bulimia-nervosa
#11
V V Grachev
AIM: To investigate affective pathology in patients with adolescent bulimia nervosa (BN) and to analyze comorbid mutual influences of these clinical entities. MATERIAL AND METHODS: A sample consisted of 52 young female patients, aged from 13.9 to 17.4 years, who simultaneously meet ICD-10 criteria of F50.2 - typical BN and F30-F39 - mood disorders. The Eating Attitudes Test (EAT-26) and the Beck Depression Inventory were used for psychometric assessment. Duration of follow-up ranged from 1 to 7 years...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28370454/direct-free-carrier-photogeneration-in-single-layer-and-stacked-organic-photovoltaic-devices
#12
Hrisheekesh Thachoth Chandran, Tsz-Wai Ng, Yishu Foo, Ho-Wa Li, Jian Qing, Xiao-Ke Liu, Chiu-Yee Chan, Fu-Lung Wong, Juan Antonio Zapien, Sai-Wing Tsang, Ming-Fai Lo, Chun-Sing Lee
High performance organic photovoltaic devices typically rely on type-II P/N junctions for assisting exciton dissociation. Heremans and co-workers recently reported a high efficiency device with a third organic layer which is spatially separated from the active P/N junction; but still contributes to the carrier generation by passing its energy to the P/N junction via a long-range exciton energy transfer mechanism. In this study the authors show that there is an additional mechanism contributing to the high efficiency...
June 2017: Advanced Materials
https://www.readbyqxmd.com/read/28365865/socio-demographic-and-clinical-characterization-of-patients-with-bipolar-disorder-i-vs-ii-a-nationwide-italian-study
#13
A Carlo Altamura, Massimiliano Buoli, Bruno Cesana, Bernardo Dell'Osso, Gianluigi Tacchini, Umberto Albert, Andrea Fagiolini, Andrea de Bartolomeis, Giuseppe Maina, Emilio Sacchetti
Bipolar disorders (BDs) are prevalent, comorbid and disabling conditions, associated with the highest suicide risk among psychiatric illnesses. In the last few years, new efforts to better characterize the socio-demographic and clinical profiles of BD type I vs II have been documented by several reports, with novel and insightful findings in the field. The present multicenter study aimed to provide a comprehensive and reliable representation of the Italian reality, through the analysis of the largest national sample of bipolar patients collected so far...
April 1, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/28360522/long-term-efficacy-and-safety-of-lamotrigine-for-all-types-of-bipolar-disorder
#14
Yoshinori Watanabe, Seiji Hongo
BACKGROUND: We investigated whether the long-term efficacy and safety of lamotrigine (LTG) for bipolar disorder (BP) differs between disease types (BP-I, BP-II, or BP not otherwise specified [BP-NOS]), and the efficacy of the concomitant use of antidepressants (ADs). METHODS: For >1 year, we observed 445 outpatients with BP (diagnosed by DSM-IV criteria) who initiated LTG treatment between July 1 and October 31, 2011, using the Himorogi Self-rating Depression (HSDS) and Anxiety Scales and the Clinical Global Impression-Improvement scale and also recorded adverse events...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28358865/ultrastructure-and-morphology-of-antennal-sensilla-of-the-adult-diving-beetle-cybister-japonicus-sharp
#15
Li-Mei Song, Xue-Min Wang, Jian-Ping Huang, Fang Zhu, Xiang Jiang, Shan-Gan Zhang, Li-Ping Ban
The morphology and distribution of the antennal sensilla of adult diving beetle Cybister japonicus Sharp (Dytiscidae, Coleoptera), have been examined. Five types of sensilla on the antennae were identified by scanning electron microscope (SEM) and transmission electron microscope (TEM). Sensilla placodea and elongated s. placodea are the most abundant types of sensilla, distributing only on the flagellum. Both these types of sensilla carry multiple pore systems with a typical function as chemoreceptors. Three types of s...
2017: PloS One
https://www.readbyqxmd.com/read/28351410/cognitive-behavioral-rehabilitation-vs-treatment-as-usual-for-bipolar-patients-study-protocol-for-a-randomized-controlled-trial
#16
Bernardo Carramão Gomes, Cristiana Castanho Rocca, Gabriel Okawa Belizario, Beny Lafer
BACKGROUND: Bipolar disorder (BD) is commonly associated with cognitive and functional impairments even during remission periods, and although a growing number of studies have demonstrated the benefits of psychotherapy as an add-on to pharmacological treatment, its effectiveness appears to be less compelling in severe presentations of the disorder. New interventions have attempted to improve cognitive functioning in BD patients, but results have been mixed. METHODS: The study consists of a clinical trial comparing a new structured group intervention, called "Cognitive-Behavioral Rehabilitation," with treatment as usual (TAU) for bipolar patients...
March 28, 2017: Trials
https://www.readbyqxmd.com/read/28346863/lymph-node-dissection-using-bipolar-vessel-sealing-device-during-reduced-port-laparoscopic-distal-gastrectomy-for-gastric-cancer-result-of-a-pilot-study-from-a-single-institute
#17
Chang Min Lee, Da Won Park, Sungsoo Park, Jong-Han Kim, Seong-Heum Park, Chong-Suk Kim
INTRODUCTION: The electrothermal bipolar vessel-sealing device (BVSD) is known to supply a strong vessel-sealing power. However, only few studies have reported lymph node dissection (LND) using only BVSD during laparoscopic surgery for gastric cancer. The purpose of this study was to investigate the feasibility of LND using BVSD during reduced port laparoscopic distal gastrectomy for gastric cancer. METHODS: From May 2015, patients in whom three- or single-port laparoscopic distal gastrectomy had been engaged for gastric cancer were enrolled in this study...
March 27, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28332122/cognitive-impairments-and-predominant-polarity-in-bipolar-disorder-a-cross-sectional-study
#18
Gabriel Okawa Belizario, Alexandre Duarte Gigante, Cristiana Castanho de Almeida Rocca, Beny Lafer
BACKGROUND: Bipolar disorder (BD) patients exhibit cognitive impairments during euthymic states. Studies suggest that manic episodes may be correlated to cognitive impairments. The present study investigated the relationship between predominant polarity and the cognitive deficits frequently detected in bipolar patients. We hypothesize that mania predominant polarity (MPP) patients should exhibit greater cognitive impairments in comparison to depressive (DPP) and indefinite predominant polarity (IPP) patients and healthy control (HC) individuals...
December 2017: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/28332121/impairment-in-emotion-perception-from-body-movements-in-individuals-with-bipolar-i-and-bipolar-ii-disorder-is-associated-with-functional-capacity
#19
Anja Vaskinn, Trine Vik Lagerberg, Thomas D Bjella, Carmen Simonsen, Ole A Andreassen, Torill Ueland, Kjetil Sundet
BACKGROUND: Individuals with bipolar disorder present with moderate impairments in social cognition during the euthymic state. The impairment extends to theory of mind and to the perception of emotion in faces and voices, but it is unclear if emotion perception from body movements is affected. The main aim of this study was to examine if participants with bipolar disorder perform worse than healthy control participants on a task using point-light displays of human full figures moving in a manner indicative of a basic emotion (angry, happy, sad, fearful, neutral/no emotion)...
December 2017: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/28327583/duration-of-untreated-bipolar-disorder-a-multicenter-study
#20
Ling Zhang, Xin Yu, Yi-Ru Fang, Gabor S Ungvari, Chee H Ng, Helen F K Chiu, Hui-Chun Li, Hai-Chen Yang, Qing-Rong Tan, Xiu-Feng Xu, Gang Wang, Yu-Tao Xiang
Little is known about the demographic and clinical differences between short and long duration of untreated bipolar disorder (DUB) in Chinese patients. This study examined the demographic and clinical features of short (≤2 years) and long DUB (>2 years) in China. A consecutively recruited sample of 555 patients with bipolar disorder (BD) was examined in 7 psychiatric hospitals and general hospital psychiatric units across China. Patients' demographic and clinical characteristics were collected using a standardized protocol and data collection procedure...
March 22, 2017: Scientific Reports
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