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https://www.readbyqxmd.com/read/28214424/association-between-plaque-characteristics-and-the-amount-of-debris-captured-by-a-filter-type-distal-protection-device-in-patients-with-acute-coronary-syndrome
#1
Katsuhide Kitagawa, Tetsuya Amano, Tadayuki Uetani, Hideki Ishii, Takahiro Okumura, Susumu Suzuki, Hiroaki Takashima, Akiyoshi Kurita, Hirohiko Ando, Tatsuaki Matsubara, Toyoaki Murohara
BACKGROUND AND AIMS: Disruption of atherosclerotic plaque and distal embolism often cause peri-procedural myocardial injury during percutaneous coronary intervention (PCI). In the present study, we evaluate the association between the characteristics of the target lesion and the amount of debris captured by the filter-type distal protection device. METHODS: We enrolled 120 consecutive patients with acute coronary syndrome, who underwent coronary stent implantation with a filter-type distal protection device after integrated backscatter intravascular ultrasound (IB-IVUS) analysis...
February 8, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28212152/an-update-on-small-bowel-endoscopy
#2
Hey-Long Ching, Mark E McAlindon, Reena Sidhu
PURPOSE OF REVIEW: The breakthrough success of capsule endoscopy and device-assisted enteroscopy has inspired researchers to test and push the boundary of these technologies. The authors herein summarize the latest and most significant studies with clinical impact. RECENT FINDINGS: Competing capsule endoscopy models have enriched the platform of this wireless device. The role of capsule endoscopy in Crohn's disease is expanding as we learn more of the significance of disease distribution and response to treatment...
February 15, 2017: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/28211642/biomechanical-strain-exacerbates-inflammation-on-a-progeria-on-a-chip-model
#3
João Ribas, Yu Shrike Zhang, Patrícia R Pitrez, Jeroen Leijten, Mario Miscuglio, Jeroen Rouwkema, Mehmet Remzi Dokmeci, Xavier Nissan, Lino Ferreira, Ali Khademhosseini
Organ-on-a-chip platforms seek to recapitulate the complex microenvironment of human organs using miniaturized microfluidic devices. Besides modeling healthy organs, these devices have been used to model diseases, yielding new insights into pathophysiology. Hutchinson-Gilford progeria syndrome (HGPS) is a premature aging disease showing accelerated vascular aging, leading to the death of patients due to cardiovascular diseases. HGPS targets primarily vascular cells, which reside in mechanically active tissues...
February 17, 2017: Small
https://www.readbyqxmd.com/read/28205029/stray-energy-transfer-during-endoscopy
#4
Edward L Jones, Amin Madani, Douglas M Overbey, Asimina Kiourti, Satheesh Bojja-Venkatakrishnan, Dean J Mikami, Jeffrey W Hazey, Todd R Arcomano, Thomas N Robinson
INTRODUCTION: Endoscopy is the standard tool for the evaluation and treatment of gastrointestinal disorders. While the risk of complication is low, the use of energy devices can increase complications by 100-fold. The mechanism of increased injury and presence of stray energy is unknown. The purpose of the study was to determine if stray energy transfer occurs during endoscopy and if so, to define strategies to minimize the risk of energy complications. METHODS AND PROCEDURES: A gastroscope was introduced into the stomach of an anesthetized pig...
February 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28191373/capecitabine-associated-loss-of-fingerprints-report-of-capecitabine-induced-adermatoglyphia-in-two-women-with-breast-cancer-and-review-of-acquired-dermatoglyphic-absence-in-oncology-patients-treated-with-capecitabine
#5
Philip R Cohen
Capecitabine, an oral 5-fluorouracil prodrug, is currently used in the treatment of metastatic colorectal carcinoma and breast cancer. Fingerprints, also referred to as dermatoglyphics and characterized by the pattern of ridges and furrows on the fingertips, are used for identification by government agencies and personal electronic devices. Two women with breast cancer who were treated with capecitabine and developed drug-associated loss of their fingerprints are described. PubMed was used to search the following terms separately and in combination: absence, adermatoglyphia, breast, cancer, capecitabine, carcinoma, colon, colorectal, dermatoglyphics, fingerprint, fluorouracil, foot, hand, loss, malignancy, nasopharyngeal, oncology, reaction, rectal, skin, syndrome, tumor, and xeloda...
January 9, 2017: Curēus
https://www.readbyqxmd.com/read/28176044/lens-management-of-cataract-surgery-cataract-prevention-and-floppy-iris-syndrome
#6
Joao Crispim, Wallace Chamon
According to the World Health Organization, cataract is the major cause of reversible visual impairment in the world. It is present as the cause of decreased visual acuity in 33% of the visual impaired citizens. With the increase of life expectancy in the last decades, the number of patients with cataract is expected to grow for the next 20 years. Nowadays, the only effective treatment for cataracts is surgery and its surgical outcomes have been increasingly satisfactory with the technological advancement...
February 8, 2017: Handbook of Experimental Pharmacology
https://www.readbyqxmd.com/read/28169555/aspiration-thrombectomy-and-intracoronary-tirofiban-via-guideliner-%C3%A2-catheter-for-a-thrombosed-aneurysmal-vessel
#7
James Fry, Ali Naqvi, Amit Bahia, Arnold Seto
A 52-year-old Asian male with no traditional risk factors for coronary artery disease presented with acute coronary syndrome. Coronary angiography showed complete thrombotic occlusion of the left circumflex with a large thrombus burden in the setting of diffuse aneurysmal enlargement of the coronary arteries consistent with antecedent Kawasaki disease. Manual thrombectomy with adjunctive intracoronary tirofiban was performed utilizing the GuideLiner catheter. Stent implantation was deferred. Follow-up imaging 48 h later showed preserved coronary flow and decreased thrombus burden...
February 7, 2017: Future Cardiology
https://www.readbyqxmd.com/read/28166812/efficacy-of-high-intensity-focused-ultrasound-assisted-hepatic-resection-hifu-ar-on-blood-loss-reduction-in-patients-with-liver-metastases-requiring-hepatectomy-study-protocol-for-a-randomized-controlled-trial
#8
Aurélien Dupré, David Pérol, Ellen Blanc, Patrice Peyrat, Valéria Basso, Yao Chen, Jérémy Vincenot, Anthony Kocot, David Melodelima, Michel Rivoire
BACKGROUND: Liver resection is the only potentially curative treatment for colorectal liver metastases (LM). It is considered a safe procedure, but is often associated with blood loss during liver transection. Blood transfusions are frequently needed, but they are associated with increased morbidity and risk of recurrence. Many surgical devices have been developed to decrease blood loss. However, none of them has proven superior to the standard crushing technique. We developed a new, powerful intra-operative high-intensity focused ultrasound (HIFU) transducer which destroys tissue by coagulative necrosis...
February 6, 2017: Trials
https://www.readbyqxmd.com/read/28165572/early-cannulation-graft-flixene%C3%A2-for-conventional-and-complex-hemodialysis-access-creation
#9
Carlos A Hinojosa, Saul Soto-Solis, Sandra Olivares-Cruz, Hugo Laparra-Escareno, Zeniff Gomez-Arcive, Javier E Anaya-Ayala
PURPOSE: The Flixene™ (Atrium™, Hudson, NH) is a trilaminate composite polytetrafluoroethylene (PTFE) graft that allows access within 72 hours. We evaluate our initial experience with this device for conventional and complex hemodialysis access creation. METHODS: Retrospective review in end-stage renal disease (ESRD) patients who underwent access creation with Flixene from January 2013 to July 2014. For our analysis, the patients were divided in two groups: those with complex access configurations tunneled in the chest and/or abdominal wall (thoraco-abdominal wall access [TAWA]), and those tunneled in conventional sites (extremity access [EA])...
February 6, 2017: Journal of Vascular Access
https://www.readbyqxmd.com/read/28163457/near-infrared-pulsed-light-for-permanent-hair-reduction-in-fitzpatrick-skin-types-iv-and-v
#10
Pratik Thacker, Pramod Kumar
BACKGROUND: Excessive hair on the face is a significant cause for distress amongst women. Permanent hair reduction methods including lasers and pulsed light devices are increasingly being used. AIMS: The aim of this study is to evaluate the efficacy and safety of near infrared pulsed light source for permanent hair reduction in women seeking treatment for excessive hair growth on the upper lip and chin. SETTINGS AND DESIGN: This was a prospective observational study done at a tertiary care hospital in South India...
October 2016: Journal of Cutaneous and Aesthetic Surgery
https://www.readbyqxmd.com/read/28160269/infections-in-cancer-patients-with-solid-tumors-a-review
#11
REVIEW
Kenneth V I Rolston
Solid tumors are much more common than hematologic malignancies. Although severe and prolonged neutropenia is uncommon, several factors increase the risk of infection in patients with solid tumors, and the presence of multiple risk factors in the same patient is not uncommon. These include obstruction (most often caused by progression of the tumor), disruption of natural anatomic barriers such as the skin and mucosal surfaces, and treatment-related factors such as chemotherapy, radiation, diagnostic and/or therapeutic surgical procedures, and the increasing use of medical devices such as various catheters, stents, and prostheses...
February 3, 2017: Infectious Diseases and Therapy
https://www.readbyqxmd.com/read/28160010/the-effect-of-sacral-neuromodulation-on-pregnancy-a-systematic-review
#12
Amr Mahran, Alex Soriano, Ahmed S Safwat, Adonis Hijaz, Sangeeta T Mahajan, Emanuel C Trabuco, Steven W Siegel, Sherif A El-Nashar
INTRODUCTION AND HYPOTHESIS: To evaluate the effects of sacral neuromodulation (SNM) on pregnancy and the impact of delivery on SNM function. METHODS: A systematic search was conducted through January 2016. We selected studies including women who had SNM and a subsequent pregnancy. RESULTS: Out of 2,316, eight studies were included, comprising 22 patients (26 pregnancies). SNM indications were Fowler's syndrome in 11, urinary retention in 6, fecal incontinence in 1, fecal and urinary urgency in 1, overactive bladder in 1, intractable interstitial cystitis in 1, and myelodysplasia in 1...
February 3, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28159327/non-invasive-transcutaneous-supraorbital-neurostimulation-tsns-using-cefaly-%C3%A2-device-in-prevention-of-primary-headaches
#13
Anna Przeklasa-Muszyńska, Kinga Skrzypiec, Magdalena Kocot-Kępska, Jan Dobrogowski, Maciej Wiatr, Joanna Mika
Headaches are one of the most common pain syndromes experienced by adult patients. International Classification of Headache Disorders identifies about 300 different entities. Primary headaches (migraine, tension-type headache, trigeminal autonomic cephalalgias, other primary headaches) has the common occurrence. Although effective treatment of these disorders is possible, it is inefficient or poorly tolerated in some patients. Neuromodulation methods, being element of multimodal treatment, provide an additional treatment option in pharmacotherapy-refractory patients...
January 20, 2017: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/28156456/prevalence-of-myofascial-pain-syndrome-in-patients-with-incurable-cancer
#14
Junya Kinkawa, Aya Watanabe, Chie Watanabe, Tsukuru Chiba, Naoki Shimada, Keisuke Ariyoshi, Masanori Nojima, Satoru Iwase, Arinobu Tojo
: 97 Background: Myofascial pain syndrome (MPS) is a condition that involves skeletal muscles. It is caused by overload or disuse of muscles and is characterized by extreme tenderness in the muscles with taut bands. Treatment for MSP is different from that for cancer-related pain. Cancer patients have many factors that cause restriction of body movement and posture. Although cancer patients appear to demonstrate risk factors for MPS, its prevalence has not been reported in patients with incurable cancer...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28155824/analysis-of-the-structure-of-the-torso-in-the-frontal-plane-in-girls-with-rett-syndrome-taking-into-account-their-functional-status
#15
Monika Małachowska-Sobieska, Katarzyna Barczyk-Pawelec, Zuzanna Marcmiszyn, Ewa Demczuk-Włodarczyk, Beata Skolimowska, Anna Maćków, Agnieszka Miler
BACKGROUND: Rett syndrome is a rare developmental disorder with a genetic background, and scoliosis is one of its many complications. The aim of the present study was to assess the structure of the torso in the frontal plane in RTT. It was assumed that asymmetry of the structure of the torso in the frontal plane would be smaller in girls who are able to maintain a vertical body position. MATERIAL AND METHODS: The study included 14 girls previously diagnosed with RTT aged between 3 and 15 years, who were divided into 2 groups...
March 23, 2016: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28145609/evaluation-of-clinical-outcomes-after-combo-stent-treatment-in-patients-presenting-with-acute-coronary-syndrome
#16
Deborah N Kalkman, Pier Woudstra, Huangling Lu, Ian B A Menown, Peter den Heijer, Harry Suryapranata, Andrés Iñiguez, Karin E Arkenbout, Arnoud W J Van't Hof, Philippe Muller, Andrejs Erglis, Jan G Tijssen, Marcel A M Beijk, Robbert J de Winter
BACKGROUND: Patients presenting with acute coronary syndrome (ACS) are at increased risk of complications after percutaneous coronary intervention with stent placement compared to patients with stable angina (SA) treated in an elective setting. The novel pro-healing COMBO stent is a bio-engineered drug eluting stent designed to promote vessel healing. Therefore, the stent may reduce this difference in clinical outcomes between elective and ACS-patients and prevent late stent thrombosis...
February 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28144166/osteopathic-treatment-in-a-patient-with-left-ventricular-assist-device-with-left-brachialgia-a-case-report
#17
Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Beatrice Sacconi
This study deals with an osteopathic approach used for a patient with left-ventricular assist device (L-VAD) affected by left brachialgia. Clinical examination revealed the presence of thoracic outlet syndrome and pectoralis minor syndrome, with compression of the left proximal ulnar nerve, related to the surgical sternotomy performed. The osteopathic techniques used can be classified as indirect and direct, addressed to the pectoralis minor and the first left rib, respectively. To our knowledge, this is the first text in literature with an osteopathic treatment in a patient with L-VAD...
2017: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/28131945/design-and-optimization-of-a-novel-implantation-technology-in-contact-lenses-for-the-treatment-of-dry-eye-syndrome-in-vitro-and-in-vivo-evaluation
#18
Furqan A Maulvi, Anjum A Shaikh, Dhara H Lakdawala, Ankita R Desai, Mihir M Pandya, Sulabh S Singhania, Rutvi J Vaidya, Ketan M Ranch, Bhavin A Vyas, Dinesh O Shah
: Contact lenses are widely used for ophthalmic drug delivery, but incorporation of drug or formulation in the contact lenses affects its optical and physical property. In the present study, we have designed a novel hyaluronic acid (HA)-laden ring implant contact lenses (modified cast moulding method), to circumvent the changes in critical lens property. The objective was to improve the ocular residence time of HA, by providing sustained ocular HA delivery through implant contact lenses for the treatment of dry eye syndrome...
January 25, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28127130/endovascular-therapy-using-flow-diversion-for-giant-internal-carotid-artery-pseudoaneurysm-arising-in-the-setting-of-an-invasive-pituitary-macroadenoma
#19
Amin F Saad, Almas Syed, Keyan B Marashi, Brian D O'Rourke, Joseph H Hise, Michael J Opatowsky, Kennith F Layton
This report illustrates the unusual occurrence of a pseudoaneurysm arising in the setting of a skull base mass and describes the first reported use of endovascular flow diversion therapy in such a setting. A 63-year-old man with occasional headaches during the preceding month presented with the acute onset of severe left retroorbital headache and oculomotor nerve palsy. Computed tomography (CT) and CT angiogram revealed a destructive skull base mass with an associated giant probable pseudoaneurysm of the cavernous segment of the left internal carotid artery...
January 2017: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/28125296/an-adapted-walking-intervention-for-a-child-with-pitt-hopkins-syndrome
#20
Amanda Faith Casey, Vanessa Pickard, Claire Ullrich, Zachary MacNeil
PURPOSE: To investigate the effects of a community-based adapted walking intervention on a child with Pitt Hopkins syndrome (PTHS). METHODS: A four-year old boy with PTHS participated in a 12-week intervention comprising five one-hour long walking sessions per week at a local daycare. Walking sessions used the Upsee mobility device (Firefly by Leckey Ltd., Ireland). Outcome measures included Goal Attainment Scaling and the Mobility Ability Participation Assessment...
January 26, 2017: Disability and Rehabilitation. Assistive Technology
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