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Leadless pacing

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https://www.readbyqxmd.com/read/29143810/next-generation-pacemakers-from-small-devices-to-biological-pacemakers
#1
REVIEW
Eugenio Cingolani, Joshua I Goldhaber, Eduardo Marbán
Electrogenesis in the heart begins in the sinoatrial node and proceeds down the conduction system to originate the heartbeat. Conduction system disorders lead to slow heart rates that are insufficient to support the circulation, necessitating implantation of electronic pacemakers. The typical electronic pacemaker consists of a subcutaneous generator and battery module attached to one or more endocardial leads. New leadless pacemakers can be implanted directly into the right ventricular apex, providing single-chamber pacing without a subcutaneous generator...
November 16, 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/29110935/successful-percutaneous-retrieval-of-a-leadless-pacemaker-due-to-an-acute-rise-in-pacing-threshold
#2
Ngai-Yin Chan, Ho-Chuen Yuen, Ngai-Shing Mok
Leadless cardiac pacemakers (LCP) have become available recently. Both its acute and long-term performance in a large population of patients remain to be tested. Subacute rise in pacing threshold has been reported as an uncommon complication. On the other hand, the retrieval technique for LCP with passive fixation mechanism has not been previously described in details. Herein we report a newly recognized complication of an acute rise in pacing threshold very soon after implantation of an LCP without radiographic dislodgement...
October 28, 2017: Indian Pacing and Electrophysiology Journal
https://www.readbyqxmd.com/read/29045345/leadless-cardiac-pacemakers-present-and-the-future
#3
Derek S Chew, Vikas Kuriachan
PURPOSE OF REVIEW: Pacing technology for many decades has been composed of a generator attached to leads that are usually transvenous. Recently, leadless pacemakers have been studied in clinical settings and now available for use in many countries. This includes the single-component Nanostim Leadless Cardiac Pacemaker and Micra Transcatheter Pacing System, as well as the multicomponent Wireless Stimulation Endocardial system. RECENT FINDINGS: Clinical studies in single-component leadless pacing technology has shown that they can be successfully implanted with minimal complications...
October 17, 2017: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/29021417/miniaturized-leadless-cardiac-pacemakers%C3%A3-can-they-overcome-the-problems-with-transvenous-pacing-systems
#4
EDITORIAL
Yasushi Oginosawa, Ritsuko Kohno, Hisaharu Ohe, Haruhiko Abe
No abstract text is available yet for this article.
October 25, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29018521/end-of-life-management-of-leadless-cardiac-pacemaker-therapy
#5
Niek Eg Beurskens, Fleur Vy Tjong, Reinoud E Knops
The clinically available leadless pacemakers for patients with a single-chamber pacing indication have shown to be safe and effective. However, the optimal end-of-life strategy of this novel technique is undefined. Suggested strategies comprise of (a) placing an additional leadless device adjacent to the leadless pacemaker, or (b) retrieving the non-functioning leadless pacemaker and subsequently implanting a new device. Although initial studies demonstrate promising results, early experience of acute and mid-term retrieval feasibility and safety remains mixed...
August 2017: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29016787/first-in-human-leadless-micra-transcatheter-pacing-system-meets-the-nanostim-leadless-cardiac-pacing-system
#6
Leif-Hendrik Boldt, Phillip Lacour, Burkert Pieske, Wilhelm Haverkamp, Florian Blaschke
No abstract text is available yet for this article.
July 27, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28965962/spanish-pacemaker-registry-14th-official-report-of-the-spanish-society-of-cardiology-working-group-on-cardiac-pacing-2016
#7
Óscar Cano Pérez, Marta Pombo Jiménez, María Luisa Fidalgo Andrés, Diego Lorente Carreño, Raúl Coma Samartín
INTRODUCTION AND OBJECTIVES: This report describes the results of analysis of implanted pacemakers reported to the Spanish Pacemaker Registry. METHODS: The analysis was based on information provided by the European Pacemaker Identification Card. RESULTS: Information was received from 115 hospitals, with a total of 12 697 cards, representing 32.3% of the estimated activity. Use of conventional and resynchronization pacemakers was 818 and 79 units per million inhabitants, respectively...
September 28, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28826669/leadless-pacemaker-performance-and-complications
#8
REVIEW
Justin Z Lee, Siva K Mulpuru, Win K Shen
Traditional transvenous cardiac pacemakers have pitfalls due to lead- and device pocket-related complications. Leadless pacemakers were developed and introduced into clinical practice to overcome the shortcomings of traditional transvenous pacemakers. In this review, we provide a description of leadless pacemaker devices, and summarize existing data on device performance. We also describe associated complications during implantation procedure as well as during the follow-up period. Although current generation devices are limited to single-chamber pacing, future generation devices are expected to progress to multi-chamber multi-component pacing systems, and eventually to battery-less devices...
August 9, 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28765766/asystole-in-focal-epilepsy-complicating-a-traumatic-subdural-hematoma
#9
Yuk-Ming Lau, Chi-Hung Lo, Kathy Lai-Fun Lee, Chu-Pak Lau
Ictal asystole due to sinus node suppression is a cause of sudden unexplained death in epilepsy. Here, for the first time, we describe a complete atrioventricular nodal block in a patient with non-compressive traumatic subdural hematoma, who developed ictal asystole as a delayed presentation. A leadless VVI pacemaker (ventricular paced, ventricular sensed, and pacing inhibited in response to a sensed beat) was implanted as a preventive measure against seizure-related heart block.
August 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28754393/totally-leadless-dual-device-implantation-for-combined-spontaneous-ventricular-tachycardia-defibrillation-and-pacemaker-function-a-first-report
#10
Fozia Zahir Ahmed, Colin Cunnington, Manish Motwani, Amir Masood Zaidi
Subcutaneous implantable cardioverter defibrillators (S-ICDs) provide effective defibrillation, while also reducing the risk of long-term lead problems. However, S-ICDs do not offer bradycardia or antitachycardia pacing and therefore use has been limited. Combined implantation of an S-ICD with a leadless pacemaker (LP) has been proposed to overcome this limitation. Although a handful of combined S-ICD/LP implantations have been reported for Nanostim (St Jude Medical, St Paul, MN) as well as Micra LP (Medtronic, Minneapolis, MN) systems, none have documented delivery of appropriate shock therapies for spontaneous ventricular tachycardia...
August 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28733849/novel-pacing-strategies-for-heart-failure-management
#11
REVIEW
Jordan S Leyton-Mange, Theofanie Mela
Cardiac resynchronization therapy has emerged as the gold standard for heart failure patients with left ventricular systolic dysfunction and electrical dyssynchrony from an intrinsic intraventricular conduction delay or right ventricular pacing. However, the limits imposed by the coronary sinus venous anatomy restrict the applicability of the technology for many potential recipients. Furthermore, conventional resynchronization, by virtue of utilizing a single site of epicardial origin for left ventricular activation, is non-physiological...
August 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28733677/inductively-powered-wireless-pacing-via-a-miniature-pacemaker-and-remote-stimulation-control-system
#12
Parinaz Abiri, Ahmad Abiri, René R Sevag Packard, Yichen Ding, Alireza Yousefi, Jianguo Ma, Malcolm Bersohn, Kim-Lien Nguyen, Dejan Markovic, Shervin Moloudi, Tzung K Hsiai
Pacemakers have existed for decades as a means to restore cardiac electrical rhythms. However, lead-related complications have remained a clinical challenge. While market-released leadless devices have addressed some of the issues, their pacer-integrated batteries cause new health risks and functional limitations. Inductive power transfer enables wireless powering of bioelectronic devices; however, Specific Absorption Rate and size limitations reduce power efficiency for biomedical applications. We designed a remote-controlled system in which power requirements were significantly reduced via intermittent power transfer to control stimulation intervals...
July 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28713024/to-retrieve-or-not-to-retrieve-system-revisions-with-the-micra-transcatheter-pacemaker
#13
Eric Grubman, Philippe Ritter, Christopher R Ellis, Michael Giocondo, Ralph Augostini, Petr Neuzil, Bipin Ravindran, Anshul M Patel, Pamela Omdahl, Karen Pieper, Kurt Stromberg, J Harrison Hudnall, Dwight Reynolds
BACKGROUND: Early experience with leadless pacemakers has shown a low rate of complications. However, little is known about system revision in patients with these devices. OBJECTIVE: The purpose of this study was to describe the system revision experience with the Micra Transcatheter Pacing System (TPS). METHODS: Implanted patients from the Pre-market Micra Transcatheter Pacing Study and the Micra Transcatheter Pacing System Continued Access Study (N = 989) were analyzed and compared with 2667 patients with transvenous pacemakers (TVP)...
July 14, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28707043/leadless-pacing-current-state-and-future-direction
#14
REVIEW
Matthias Merkel, Philipp Grotherr, Andrea Radzewitz, Claus Schmitt
Leadless pacing is now an established alternative to conventional pacing with subcutaneous pocket and transvenous lead for patients with class I or II single-chamber pacing indication. Available 12-month follow-up data shows a 48% fewer major complication rate in patients with Micra™ compared to a historical control group in a nonrandomized study [1]. There is one system with Food and Drug Administration (FDA) approval and two with the Communauté Européenne (CE) mark. The OPS code for the implantation is 8-83d...
December 2017: Cardiology and Therapy
https://www.readbyqxmd.com/read/28705736/a-worldwide-experience-of-the-management-of-battery-failures-and-chronic-device-retrieval-of-the-nanostim-leadless-pacemaker
#15
Dhanunjaya Lakkireddy, Reinoud Knops, Brett Atwater, Petr Neuzil, John Ip, Elkin Gonzalez, Paul Friedman, Pascal Defaye, Derek Exner, Kazutaka Aonuma, Rahul Doshi, Johannes Sperzel, Vivek Reddy
BACKGROUND: The Nanostim leadless pacemaker (LP) met the primary endpoints in an investigational device exemption trial, and was shown to be fully retrievable percutaneously. In October 2016, St Jude Medical issued a worldwide alert of a battery malfunction that caused lost pacing output and LP communication. OBJECTIVE: To report the battery failure mechanism and incidence and the worldwide patient management, including device retrieval experiences. METHODS: The affected LP battery is a custom lithium-carbon monofluoride cell...
July 10, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28696087/leadless-technology-a-new-paradigm-for-cardiac-pacing
#16
Giulio Zucchelli, Valentina Barletta, Maria G Bongiorni
Leadless pacemaker (LP) technology was recently developed and introduced for clinical purpose as an alternative to traditional systems in order to reduce leads and pocket-related complications. Currently, two self-contained right ventricular pacemaker implanted by using a femoral percutaneous approach have been developed and initial results seem promising. Although the clinical use is still limited to the right ventricular pacing, the LP currently represents a valid and alternative solution in several settings, when the standard pacemaker cannot be used or its use is associated with higher risk of complications...
July 10, 2017: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/28666317/right-ventricular-and-tricuspid-valve-function-in-patients-chronically-implanted-with-leadless-pacemakers
#17
Erwan Salaun, Lilith Tovmassian, Blandine Simonnet, Roch Giorgi, Frédéric Franceschi, Linda Koutbi-Franceschi, Jérôme Hourdain, Gilbert Habib, Jean-Claude Deharo
Aims: Leadless cardiac pacing has recently been proposed as alternative to conventional right ventricular (RV) pacing. With this approach, devices are directly screwed or fixed with tines in the RV wall, but the possible consequences on RV and tricuspid valve (TV) structure and function remain unknown. We thus conducted a study to evaluate this potential impact in chronically implanted patients. Methods and results: Repeated echocardiographic studies were performed prior to implantation, at discharge, and 2 months thereafter on all consecutive patients implanted with a leadless pacemaker at our centre between October 2014 and end-December 2015...
June 28, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28606633/leadless-pacing-meets-the-real-world-the-maturation-of-clinical-evidence-behind-a-miniaturized-pacemaker
#18
EDITORIAL
Mark W Preminger, Suneet Mittal
No abstract text is available yet for this article.
June 10, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28595994/-news-techniques-of-pacing-in-congenital-heart-diseases
#19
REVIEW
Mathieu Le Bloa, Jean-Benoît Thambo
The number of children and adult with congenital heart disease requiring implantation of cardiac pacemaker or cardioverter defibrillator is constantly increasing. The lead between stimulation/defibrillation site and the generator constitutes the main weakpoint of those devices despite the numerous recent technological advances: use of bipolar probes, corticoid elution electrodes, insulation improvement, magnetic resonance imaging (MRI) compatibility. Risk of device failure remains high in this population. Long term adverse events with endovascular devices remain high...
June 2017: La Presse Médicale
https://www.readbyqxmd.com/read/28566657/performance-of-leadless-pacemaker-in-japanese-patients-vs-rest-of-the-world%C3%A3-results-from-a-global-clinical-trial
#20
Kyoko Soejima, Taku Asano, Toshiyuki Ishikawa, Kengo Kusano, Toshiaki Sato, Hideo Okamura, Katsumi Matsumoto, Wataru Taguchi, Kurt Stromberg, Jeff Lande, Youichi Kobayashi
BACKGROUND: A global study designed to demonstrate the safety and efficacy of a transcatheter pacing system included 38 Japanese patients enrolled at 4 sites. Subgroup analysis to evaluate the performance of the leadless intracardiac transcatheter pacing system in Japanese patients was performed.Methods and Results:Safety and efficacy outcomes, patient and implant procedure characteristics, and patient and physician acceptability from the Japanese population were compared with those from outside Japan...
October 25, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
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