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https://www.readbyqxmd.com/read/29781652/the-agreement-between-clients-and-their-therapists-ratings-of-personality-disorder-traits
#1
Douglas B Samuel, Takakuni Suzuki, Meredith A Bucher, Sarah A Griffin
OBJECTIVE: Treating clinicians provide the majority of mental health diagnoses, yet little is known about the validity of their routine diagnoses, including the agreement with clients' self-reports. This is particularly notable for personality disorders (PDs) as the literature suggests weak agreement between therapists and clients. Existing research has been limited by a focus on PD categories and brief therapist-report measures. Furthermore, although self-reports of PD have been criticized for underreporting, very few data have compared them with therapist report in terms of mean level...
June 2018: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/29780795/a-novel-de-novo-mutation-in-the-cd40-ligand-gene-in-a-patient-with-a-mild-x-linked-hyper-igm-phenotype-initially-diagnosed-as-cvid-new-aspects-of-old-diseases
#2
Tábata T França, Luiz F B Leite, Tiago A Maximo, Christiane G Lambert, Nuria B Zurro, Wilma C N Forte, Antonio Condino-Neto
Mutations in the CD40 ligand (CD40L) gene ( CD40LG ) lead to X-linked hyper-IgM syndrome (X-HIGM), which is a primary immunodeficiency (PID) characterized by decreased serum levels of IgG and IgA and normal or elevated IgM levels. Although most X-HIGM patients become symptomatic during the first or second year of life, during which they exhibit recurrent infections, some patients exhibit mild phenotypes, which are usually associated with hypomorphic mutations that do not abrogate protein expression or function...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29777376/comprehensive-molecular-diagnosis-of-epstein-barr-virus-associated-lymphoproliferative-diseases-using-next-generation-sequencing
#3
Shintaro Ono, Manabu Nakayama, Hirokazu Kanegane, Akihiro Hoshino, Saeko Shimodera, Hirofumi Shibata, Hisanori Fujino, Takahiro Fujino, Yuta Yunomae, Tsubasa Okano, Motoi Yamashita, Takahiro Yasumi, Kazushi Izawa, Masatoshi Takagi, Kohsuke Imai, Kejian Zhang, Rebecca Marsh, Capucine Picard, Sylvain Latour, Osamu Ohara, Tomohiro Morio
Epstein-Barr virus (EBV) is associated with several life-threatening diseases, such as lymphoproliferative disease (LPD), particularly in immunocompromised hosts. Some categories of primary immunodeficiency diseases (PIDs) including X-linked lymphoproliferative syndrome (XLP), are characterized by susceptibility and vulnerability to EBV infection. The number of genetically defined PIDs is rapidly increasing, and clinical genetic testing plays an important role in establishing a definitive diagnosis. Whole-exome sequencing is performed for diagnosing rare genetic diseases, but is both expensive and time-consuming...
May 18, 2018: International Journal of Hematology
https://www.readbyqxmd.com/read/29761842/design-and-performance-evaluation-of-real-time-endovascular-interventional-surgical-robotic-system-with-high-accuracy
#4
Kundong Wang, Bing Chen, Qingsheng Lu, Hongbing Li, Manhua Liu, Yu Shen, Zhuoyan Xu
BACKGROUND: Endovascular interventional surgery (EIS) is performed under a high radiation environment at the sacrifice of surgeons' health. This paper introduces a novel endovascular interventional surgical robot that aims to reduce radiation to surgeons and physical stress imposed by lead aprons during fluoroscopic X-ray guided catheter intervention. METHODS: The unique mechanical structure allowed the surgeon to manipulate the axial and radial motion of the catheter and guide wire...
May 15, 2018: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://www.readbyqxmd.com/read/29761739/efficacy-safety-and-quality-of-life-in-patients-receiving-subcutaneous-igg-treatment-experience-in-bogot%C3%A3-colombia
#5
María Claudia Ortega-López, Javier Garay, Mónica León Pinilla
AIM: Investigate efficacy, safety and quality of life of gammanorm® 16.5% (subcutaneous immunoglobulin [SCIG]) in patients with primary immunodeficiencies (PIDs) and safety and to lesser extent efficacy in autoimmune diseases. PATIENTS & METHODS: Medical records were extracted from 31 pediatric and 12 adult patients who received SCIG as part of the Personalized Program at University Children's Hospital, Bogotá, Colombia. RESULTS: Mean SCIG dose was 28...
May 15, 2018: Immunotherapy
https://www.readbyqxmd.com/read/29759597/performance-and-robustness-of-optimal-fractional-fuzzy-pid-controllers-for-pitch-control-of-a-wind-turbine-using-chaotic-optimization-algorithms
#6
Amirhossein Asgharnia, Reza Shahnazi, Ali Jamali
The most studied controller for pitch control of wind turbines is proportional-integral-derivative (PID) controller. However, due to uncertainties in wind turbine modeling and wind speed profiles, the need for more effective controllers is inevitable. On the other hand, the parameters of PID controller usually are unknown and should be selected by the designer which is neither a straightforward task nor optimal. To cope with these drawbacks, in this paper, two advanced controllers called fuzzy PID (FPID) and fractional-order fuzzy PID (FOFPID) are proposed to improve the pitch control performance...
May 11, 2018: ISA Transactions
https://www.readbyqxmd.com/read/29757006/continuity-between-dsm-5-section-ii-and-iii-personality-disorders-in-a-dutch-clinical-sample
#7
Irene M J Orbons, Gina Rossi, Roel Verheul, Mirjam J A Schoutrop, Jan L L Derksen, Daniel L Segal, Sebastiaan P J van Alphen
The goal of this study was to evaluate the continuity across the Section II personality disorders (PDs) and the proposed Section III model of PDs in the Diagnostic and Statistical Manual of Mental Disorders (5th ed. [DSM-5]; American Psychiatric Association, 2013a ). More specifically, we analyzed association between the DSM-5 Section III pathological trait facets and Section II PDs among 110 Dutch adults (M age = 35.8 years, range = 19-60 years) receiving mental health care. We administered the Structured Clinical Interview for DSM-IV Axis II Disorders to all participants...
May 14, 2018: Journal of Personality Assessment
https://www.readbyqxmd.com/read/29756068/patient-satisfaction-and-treatment-adherence-for-urban-adolescents-and-young-adults-with-pelvic-inflammatory-disease
#8
Jennifer Anders, Alexandra Hill, Shang-En Chung, Arlene Butz, Richard Rothman, Charlotte Gaydos, Jamie Perin, Maria Trent
Objectives: Urban adolescents with pelvic inflammatory disease (PID) often seek care in emergency departments (ED). This study examines the effect of the ED patient experience - wait time (WT) and length of stay (LOS) - on satisfaction and medication adherence among urban adolescents with PID. Methods: Adolescents with PID were enrolled in an urban teaching hospital ED. Chart data were matched with 2-week interview queries about satisfaction and medication adherence...
January 2018: Trauma and Emergency Care
https://www.readbyqxmd.com/read/29749366/experimental-zika-virus-infection-in-aedes-aegypti-susceptibility-transmission-co-infection-with-dengue-chikungunya-viruses
#9
Devendra T Mourya, Mangesh D Gokhale, Triparna D Majumdar, Pragya D Yadav, Vimal Kumar, Mangala S Mavale
Background & objectives: There are reports about the susceptibility of Aedes mosquitoes to ZIKV from various countries, however, no such information is available from Indian sub-continent, although, high level of group cross-reactivity of ZIKV with other flaviviruses has been reported. During outbreak situations, many cases of Dengue (DEN) and Chikungunya (CHIK) are reported. In such scenario, vector mosquitoes are likely to get co-infection/secondary-infection with one or other virus...
January 2018: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29745553/-the-design-of-weight-loss-walking-rehabilitation-training-system-of-differential-pressure-style
#10
Wenchao Zhu, Xiulin Xu, Xiaoming Yao, Guanpo Ma, Dongheng Zhang
This research is to develop a weight-loss walking rehabilitation training system based on differential air pressure. The system adopted Proportion-Integral-Derivative (PID) algorithm to improve the precision of weight loss, taking MSP430F149 microprocessor of Texas Instruments as the core of pressure control system. The training software is designed based on Microsoft Visual C++ 6.0 of Microsoft. The system can provide comfortable training environment for patients with lower limb motor function impediment, and can collect electromyographic signals from patients, so as to further the scientific and normative management of the patient's information...
August 1, 2017: Sheng Wu Yi Xue Gong Cheng Xue za Zhi, Journal of Biomedical Engineering, Shengwu Yixue Gongchengxue Zazhi
https://www.readbyqxmd.com/read/29731008/molecular-classification-of-primary-immunodeficiencies-of-t-lymphocytes
#11
William A Comrie, Michael J Lenardo
Proper regulation of the immune system is required for protection against pathogens and preventing autoimmune disorders. Inborn errors of the immune system due to inherited or de novo germline mutations can lead to the loss of protective immunity, aberrant immune homeostasis, and the development of autoimmune disease, or combinations of these. Forward genetic screens involving clinical material from patients with primary immunodeficiencies (PIDs) can vary in severity from life-threatening disease affecting multiple cell types and organs to relatively mild disease with susceptibility to a limited range of pathogens or mild autoimmune conditions...
2018: Advances in Immunology
https://www.readbyqxmd.com/read/29729973/digital-pi-pd-controller-design-for-arbitrary-order-systems-dominant-pole-placement-approach
#12
Emre Dincel, Mehmet Turan Söylemez
In this paper, a digital PI-PD controller design method is proposed for arbitrary order systems with or without time-delay to achieve desired transient response in the closed-loop via dominant pole placement approach. The digital PI-PD controller design problem is solved by converting the original problem to the digital PID controller design problem. Firstly, parametrization of the digital PID controllers which assign dominant poles to desired location is done. After that the subset of digital PID controller parameters in which the remaining poles are located away from the dominant pole pair is found via Chebyshev polynomials...
May 2, 2018: ISA Transactions
https://www.readbyqxmd.com/read/29720385/rates-of-pelvic-inflammatory-disease-and-ectopic-pregnancy-in-australia-2009-2014-ecological-analysis-of-hospital-data
#13
Jane L Goller, Alysha M De Livera, Rebecca J Guy, Nicola Low, Basil Donovan, Matthew Law, John M Kaldor, Christopher K Fairley, Jane S Hocking
OBJECTIVE: To analyse yearly rates of pelvic inflammatory disease (PID) and ectopic pregnancy (EP) diagnosed in hospital settings in Australia from 2009 to 2014. METHODS: We calculated yearly PID and EP diagnosis rates in three states (Victoria, New South Wales, Queensland) for women aged 15-44 years using hospital admissions and emergency department (ED) attendance data, with population and live birth denominators. We stratified PID diagnoses as chlamydial-related or gonorrhoeal-related ( Chlamydia trachomatis (CT)-related or Neisseria gonorrhoeae (NG)-related), acute, unspecified and chronic, and analysed variations by year, age and residential area using Poisson regression models...
May 2, 2018: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/29717901/faking-good-an-investigation-of-social-desirability-and-defensiveness-in-an-inpatient-sample-with-personality-disorder-traits
#14
Margot M Williams, Richard Rogers, Allyson J Sharf, Colin A Ross
Accurate interpretations of psychological assessments rely heavily on forthright reporting. However, researchers and practitioners recognize that examinees can easily invalidate their test results by underreporting symptoms or overstating positive attributes. Rogers (2008) delineated two distinct but related forms of positive impression management (PIM): defensiveness (denying symptoms and psychological impairment) and social desirability (putting forth an exaggeratedly positive image). Although these two have often been combined in past research, this study sought to investigate each separately via a mixed within- and between-subjects simulation design...
May 2, 2018: Journal of Personality Assessment
https://www.readbyqxmd.com/read/29713328/high-incidence-of-severe-combined-immunodeficiency-disease-in-saudi-arabia-detected-through-combined-t-cell-receptor-excision-circle-and-next-generation-sequencing-of-newborn-dried-blood-spots
#15
Hamoud Al-Mousa, Ghadah Al-Dakheel, Amal Jabr, Fahd Elbadaoui, Mohamed Abouelhoda, Mansoor Baig, Dorota Monies, Brian Meyer, Abbas Hawwari, Majed Dasouki
Severe combined immunodeficiency disease (SCID) is the most severe form of primary immunodeficiency disorders (PID). T-cell receptor excision circle (TREC) copy number analysis is an efficient tool for population-based newborn screening (NBS) for SCID and other T cell lymphopenias. We sought to assess the incidence of SCID among Saudi newborn population and examine the feasibility of using targeted next generation sequencing PID gene panel (T-NGS PID) on DNA isolated from dried blood spots (DBSs) in routine NBS programs as a mutation screening tool for samples with low TREC count...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29709453/lc-q-tof-ms-based-plasma-metabolomic-profile-of-subclinical-pelvic-inflammatory-disease-a-pilot-study
#16
Wei Zou, Xiaoke Wen, Chunhong Xie, Lan Nie, Qian Zhou, Xiaocui Chen, Chaoying Fang, Yichao Wang, Li Zhang
BACKGROUND: No index for non-invasive diagnosis of subclinical pelvic inflammatory disease (PID) is available at this time. Here we carried out a plasma metabolomic study to search for potential biomarkers to facilitate its non-invasive diagnosis. METHOD: The metabolites in plasma were detected by using an LC-Q-TOF-MS method. The metabolic profiles of subclinical PID patients and healthy controls were discriminated by multivariate analysis. 30 patients and 28 controls were enrolled for PLS-DA model construction, and further 8 patients and 8 controls were employed for model validation...
April 27, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29692618/an-evaluation-of-the-budget-impact-of-a-new-20-subcutaneous-immunoglobulin-ig20gly-for-the-management-of-primary-immunodeficiency-diseases-in-switzerland
#17
Richard F Pollock, Lisa M Meckley
Introduction: While most individual primary immunodeficiency diseases (PID) are rare, the collective prevalence of PID results in a substantial economic and clinical burden. The aim of this study was to evaluate the budgetary implications of Ig20Gly (Immune Globulin Subcutaneous [human] 20% solution; CUVITRU ® , Baxalta US Inc, now part of Shire Plc, Westlake Village, CA, USA) as a treatment for PID relative to intravenous immunoglobulin (IVIG) and other subcutaneous immunoglobulin (SCIG) formulations in the Swiss health care setting...
2018: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/29690826/mesenchymal-stem-cell-derived-exosomes-provide-neuroprotection-and-improve-long-term-neurologic-outcomes-in-a-swine-model-of-traumatic-brain-injury-and-hemorrhagic-shock
#18
Aaron M Williams, Isabel S Dennahy, Umar F Bhatti, Ihab Halaweish, Ye Xiong, Panpan Chang, Vahagn C Nikolian, Kiril Chtraklin, Jordana Brown, Yanlu Zhang, Zheng Gang Zhang, Michael Chopp, Benjamin Buller, Hasan B Alam
Combined traumatic brain injury (TBI) and hemorrhagic shock (HS) remains a leading cause of preventable death worldwide. Mesenchymal stem cell-derived exosomes have demonstrated promise in small animal models of neurologic injury. To investigate the effects of exosome treatment in a clinically realistic large animal model, Yorkshire swine were subjected to TBI and HS. Animals were maintained in shock for 2 hours prior to resuscitation with normal saline (NS). Animals were then either resuscitated with NS (3 x volume of shed blood) or with the same volume of NS with delayed exosome administration (1x10<sup>13</sup> particles/4ml) (n=5/cohort)...
April 25, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29690741/-antiseptic-effect-of-compound-lysostaphin-disinfectant-and-its-preventive-effect-on-infection-of-artificial-dermis-after-graft-on-full-thickness-skin-defect-wound-in-rats
#19
J Jin, H Zhou, Z C Cui, L Wang, P F Luo, S Z Ji, X Y Hu, B Ma, G Y Wang, S H Zhu, Z F Xia
Objective: To study the antiseptic effect of compound lysostaphin disinfectant and its preventive effect on infection of artificial dermis after graft on full-thickness skin defect wound in rats. Methods: (1) Each one standard strain of Klebsiella pneumoniae, Acinetobacter baumannii, and Staphylococcus aureus were selected. Each 20 clinical strains of Klebsiella pneumoniae, Acinetobacter baumannii, and Staphylococcus aureus were collected from those isolated from wound exudates of burn patients hospitalized in our wards from January 2014 to December 2016 according to the random number table...
April 20, 2018: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/29687245/development-and-characterization-of-12-polymorphic-microsatellite-loci-in-the-sea-sandwort-honckenya-peploides
#20
Meg C Gravley, George K Sage, Sandra L Talbot, Matthew L Carlson
Codominant marker systems are better suited to analyze population structure and assess the source of an individual in admixture analyses. Currently, there is no codominant marker system using microsatellites developed for the sea sandwort, Honckenya peploides (L.) Ehrh., an early colonizer in island systems. We developed and characterized novel microsatellite loci from H. peploides, using reads collected from whole genome shotgun sequencing on a 454 platform. The combined output from two shotgun runs yielded a total of 62,669 reads, from which 58 loci were screened...
April 23, 2018: Journal of Plant Research
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