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anti Mullerian hormone

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https://www.readbyqxmd.com/read/29770362/study-of-anti-m%C3%A3-llerian-hormone-levels-in-patients-with-myotonic-dystrophy-type-1-preliminary-results
#1
Manuela Ergoli, Massimo Venditti, Raffaele Dotolo, Esther Picillo, Sergio Minucci, Luisa Politano
Myotonic dystrophy type 1 is a multisystemic disorder characterized by myotonia, muscle weakness and involvement of several organs and apparatus such as heart, lungs, eye, brain and endocrine system. Hypogonadism and reproductive abnormalities are frequently reported. A progressive testicular atrophy occurs in about 80% in the affected males leading to Leydig cell hyperproliferation and elevated basal follicle stimulating hormone (FSH) levels. Anti-Müllerian hormone (AMH) - a dimeric glycoprotein belonging to the super-family of transforming grow factor beta (TGF-beta) - is the earliest Sertoli cell hormone secreted in males and, together with inhibin B and FSH, is an important indicator of Sertoli cell function...
December 2017: Acta Myologica: Myopathies and Cardiomyopathies: Official Journal of the Mediterranean Society of Myology
https://www.readbyqxmd.com/read/29765438/decline-in-ovarian-reserve-may-be-an-undiagnosed-reason-for-unexplained-infertility-a-cohort-study
#2
Burak Yücel, Sefa Kelekci, Emine Demirel
Introduction: Unexplained infertility refers to the absence of a definable cause for a couple's failure to achieve pregnancy. Reproductive aging plays a role in pathogenesis of unexplained infertility. We investigated the results of ovarian reserve tests in unexplained infertility. Material and methods: The patients were divided into two groups: unexplained infertility ( n = 148) and male factor infertility ( n = 112). Follicle-stimulating hormone, estradiol, inhibin b levels and anti-Müllerian hormone levels were evaluated...
April 2018: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/29765437/evaluation-of-ovarian-reserve-in-women-with-overt-or-subclinical-hypothyroidism
#3
Ferit Kerim Kucukler, Umit Gorkem, Yasin Simsek, Ramazan Kocabas, Serdar Guler
Introduction: Thyroid dysfunction is among the most common autoimmune disorders in women of reproductive age. Previous studies have shown the association between autoimmune thyroid disease (AITD) and infertility. Anti-Müllerian hormone (AMH) is secreted by granulosa cells and is a useful marker for assessment of ovarian reserve. In the present study, we sought to evaluate the ovarian reserves of women with autoimmune thyroid disorder by measurement of AMH values. Material and methods: This prospective study included women with newly diagnosed AITD aged between 20 and 40 years...
April 2018: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/29764793/evaluation-of-the-ovarian-reserve-in-adolescents-with-hashimoto-s-thyroiditis-using-serum-anti-m%C3%A3-llerian-hormone-levels
#4
Ezgi Özalp Akın, Zehra Aycan
OBJECTIVE: This study aims to evaluate the ovarian reserve of the adolescent girls with Hashimoto's thyroiditis (HT) with serum anti-müllerian hormone (AMH) levels and compare to healthy adolescents. It is hypothesized that HT decreases ovarian reserve and AMH levels are lower in the HT group. METHOD: Thirty HT patients aged between 10-18 years and 30 healthy girls as the control group are enrolled in this cross-sectional study. The mean serum AMH levels of the groups are compared using the Mann-Whitney U test...
May 16, 2018: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/29760445/elevated-prenatal-anti-m%C3%A3-llerian-hormone-reprograms-the-fetus-and-induces-polycystic-ovary-syndrome-in-adulthood
#5
Brooke Tata, Nour El Houda Mimouni, Anne-Laure Barbotin, Samuel A Malone, Anne Loyens, Pascal Pigny, Didier Dewailly, Sophie Catteau-Jonard, Inger Sundström-Poromaa, Terhi T Piltonen, Federica Dal Bello, Claudio Medana, Vincent Prevot, Jerome Clasadonte, Paolo Giacobini
Polycystic ovary syndrome (PCOS) is the main cause of female infertility worldwide and corresponds with a high degree of comorbidities and economic burden. How PCOS is passed on from one generation to the next is not clear, but it may be a developmental condition. Most women with PCOS exhibit higher levels of circulating luteinizing hormone, suggestive of heightened gonadotropin-releasing hormone (GnRH) release, and anti-Müllerian hormone (AMH) as compared to healthy women. Excess AMH in utero may affect the development of the female fetus...
May 14, 2018: Nature Medicine
https://www.readbyqxmd.com/read/29758382/effects-of-exposure-to-bpf-on-development-and-sexual-differentiation-during-early-life-stages-of-zebrafish-danio-rerio
#6
Qian Yang, Xianhai Yang, Jining Liu, Yingwen Chen, Shubao Shen
Bisphenol F (BPF) has become a predominant bisphenol contaminant in recent years. It has significant estrogenic properties in both in vivo and in vitro studies. We have previously studied the disrupting mechanisms of BPF on the hypothalamic-pituitary-gonadal axis of adult zebrafish. However, the effects of BPF exposure on development and sexual differentiation of zebrafish embryos/larvae remain unclear. To determine the effects of BPF on the critical stage of sex differentiation in zebrafish, zebrafish embryos/larvae were exposed to 1, 10, 100, and 1000 μg/L BPF from fertilization to 60 days post-fertilization (dpf)...
May 11, 2018: Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP
https://www.readbyqxmd.com/read/29754264/one-year-impact-of-bariatric-surgery-on-serum-anti-mullerian-hormone-levels-in-severely-obese-women
#7
Clara Vincentelli, Marie Maraninchi, René Valéro, Sophie Béliard, Flavia Maurice, Olivier Emungania, Bruno Berthet, Elise Lombard, Anne Dutour, Bénédicte Gaborit, Blandine Courbiere
INTRODUCTION: Although bariatric surgery seems to increase spontaneous fertility by improving ovulatory function in young women, its impact on ovarian reserve remains largely unknown. OBJECTIVE: To evaluate changes in serum anti-Mullerian hormone (AMH) levels in reproductive-age severely obese women after bariatric surgery (BS). METHODS: AMH levels were measured retrospectively in 39 women (mean age 34.6 ± 1.1 years, range 18-45) that underwent a sleeve gastrectomy or Roux-en-Y gastric bypass (RYGB) at baseline, and 6 and 12 months after BS...
May 12, 2018: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29752986/perinatal-bpa-exposure-and-reproductive-axis-function-in-cd-1-mice
#8
Nicole Acevedo, Beverly S Rubin, Cheryl M Schaeberle, Ana M Soto
Perinatal Bisphenol-A (BPA) exposure reduces fertility and fecundity in mice. This study examined effects of early BPA exposure on activation of gonadotropin releasing hormone (GnRH) neurons in conjunction with a steroid-induced luteinizing hormone (LH) surge, characterized patterns of estrous cyclicity and fertility over time, and assessed the ovarian follicular reserve to further explore factors responsible for the reduced fertility we previously described in this model. The percent activated GnRH neurons was reduced in BPA exposed females at 3-6 months, and periods of persistent proestrus was increased...
May 9, 2018: Reproductive Toxicology
https://www.readbyqxmd.com/read/29749518/effects-of-chronic-unpredictable-mild-stress-on-ovarian-reserve-in-female-rats-feasibility-analysis-of-a-rat-model-of-premature-ovarian-failure
#9
Xiao-Yan Fu, Hao-Hao Chen, Ning Zhang, Ming-Xing Ding, Ying-Er Qiu, Xiao-Ming Pan, Yuan-Shu Fang, Yi-Ping Lin, Qun Zheng, Wen-Qian Wang
Premature ovarian failure (POF) results from a number of disorders. The POF model is primarily based on chemotherapeutic injury, and hence is not suitable for assessing the effects of chronic stress on ovarian function. Therefore, improved animal models are required to analyze the effects of chronic stress on ovarian reserve. The feasibility of the chronic unpredictable mild stress (CUMS) method for establishing a model of POF was examined. The depressive behavior exhibited by rats was evaluated with the open field and sucrose preference tests...
May 8, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29742446/quantification-of-m%C3%A3-llerian-inhibiting-substance-anti-m%C3%A3-llerian-hormone-polypeptide-by-isotope-dilution-mass-spectrometry
#10
Gail Whiting, Jackie Ferguson, Min Fang, David Pepin, Patricia Donahoe, Paul Matejtschuk, Chris Burns, Jun X Wheeler
Measurement of serum concentrations of Müllerian inhibiting substance (MIS), also known as anti-Müllerian Hormone (AMH) by immunoassay is gaining clinical acceptance and widespread use for the diagnosis of ovarian conditions and for prediction of the response to ovarian stimulation protocols as part of assisted reproductive therapies. Provision of an International Standard to harmonize immunoassay methods is required. It is desirable for the content of a future International Standard to be assigned in mass units for consistency with the units reported by current methods...
May 6, 2018: Analytical Biochemistry
https://www.readbyqxmd.com/read/29738982/anti-m%C3%A3-llerian-hormone-levels-are-associated-with-live-birth-rates-in-art-but-the-predictive-ability-of-anti-m%C3%A3-llerian-hormone-is-modest
#11
Sara S E Alson, Leif J Bungum, Aleksander Giwercman, Emir Henic
OBJECTIVES: The aim was to evaluate the association between serum Anti-Müllerian Hormone (AMH) level and cumulative live birth rates (LBR) in patients undergoing their first in vitro fertilization (IVF) treatment cycle, and to compare serum AMH levels with Antral Follicle Count (AFC) and Ovarian Sensitivity Index (OSI) as predictors of live birth. STUDY DESIGN: A prospective cohort study of 454 patients under the age of 40 and with a regular menstrual cycle of 21-35 days, undergoing their first IVF treatment cycles between September 2010 and June 2015...
May 2, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29738413/is-ovarian-reserve-associated-with-body-mass-index-and-obesity-in-reproductive-aged-women-a-meta-analysis
#12
Nazanin Moslehi, Sakineh Shab-Bidar, Fahimeh Ramezani Tehrani, Parvin Mirmiran, Fereidoun Azizi
OBJECTIVE: The associations of body mass index (BMI) and obesity with ovarian reserve are controversial. This systematic review and meta-analysis was conducted to investigate the associations in reproductive-aged women. METHODS: PubMed and Scopus were searched up to December, 2016. Original studies on the association of BMI with ovarian reserve markers, anti-Mullerian hormone (AMH), follicle-stimulating hormone (FSH), inhibin β, and antral follicle count (AFC), either according to BMI categories or a continuous variable, were selected...
May 7, 2018: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29738164/-seminal-plasma-anti-m%C3%A3-llerian-hormone-and-inhibin-b-and-serum-inhibin-b-in-predicting-the-outcome-of-routine-ivf-fertilization
#13
Yan-Fei Wang, Xin Wu, Rong Hu, Fei-Miao Wang, Shao-Tong Jia, Li-Guo Pei, Hui Wang, Xiao-E Ouyang, Ting Hu, Yun-Xing Fu
Objective: To analyze the correlations of seminal plasma (sp) anti-Müllerian hormone (spAMH) and inhibin B (spINHB) and serum INHB (serINHB) with semen parameters in oligoasthenospermia patients and explore their value in predicting the outcome of routine in vitro fertilization (IVF). METHODS: We obtained the levels of spAMH, spINHB and serINHB as well as semen parameters from 88 infertile males undergoing IVF due to oligoasthenospermia or female uterine tubal factors from August 2016 to February 2017...
November 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29731629/nanosized-titanium-dioxide-induced-premature-ovarian-failure-is-associated-with-abnormalities-in-serum-parameters-in-female-mice
#14
Fashui Hong, Ling Wang
Background: Exposure to titanium dioxide nanoparticles (TiO2 NPs) that are widely used in food, medicine, sunscreen products and cosmetics is reported to cause ovarian damage and lower fertility in animals. However, the potential effects of TiO2 NPs application on premature ovarian failure (POF) have rarely been evaluated to date. Methods: In this study, female mice were continuously exposed to TiO2 NPs at doses of 2.5, 5 or 10 mg/kg via gavage instillation for 30 days, and investigated the serum hormones and autoimmunity markers associated with POF...
2018: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29729909/the-relationship-between-serum-anti-m%C3%A3-llerian-hormone-concentrations-and-fertility-and-genome-wide-associations-for-anti-m%C3%A3-llerian-hormone-in-holstein-cows
#15
M Gobikrushanth, D C Purfield, M G Colazo, S T Butler, Z Wang, D J Ambrose
The objectives of this study were to (1) evaluate factors associated with variation in circulating anti-Müllerian hormone (AMH) concentrations, (2) establish an optimum AMH threshold predictive of pregnancy to first artificial insemination (P/AI), (3) examine the relationship between AMH and fertility (P/AI, pregnancy loss between 30 and 60 d after artificial insemination, and pregnancy risk up to 250 d postpartum), and (4) identify quantitative trait loci associated with phenotypic variation of AMH concentrations in dairy cows...
May 2, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29726646/-orchidopexy-increases-the-levels-of-serum-anti-m%C3%A3-llerian-hormone-and-inhibin-b-in-cryptorchidism-patients
#16
Shun-Shun Cao, Yang-Yang Hu, Cun-Jin Nan
Objective: To investigate the levels of serum anti-Müllerian hormone (AMH) and inhibin B (INHB) in patients with unilateral cryptorchidism before and after orchidopexy. METHODS: This study included 58 cases of unilateral cryptorchidism treated by orchidopexy and 32 healthy controls. Before and at 6 months after surgery, we measured the length and circumference of the penis, the volume of the undescended testis, and levels of serum AMH and INHB. RESULTS: There were statistically significant differences between the unilateral cryptorchidism and healthy control groups in the levels of serum AMH ([102...
August 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29725281/ovarian-reserve-evaluation-after-laparoscopic-cyst-enucleation-depending-on-applied-haemostasis-technique-and-with-particular-consideration-of-endometrial-cysts
#17
Dariusz Owczarek, Andrzej Malinowski, Miłosz Wilczyński
Aim of the study: was an evaluation of the effects, exerted by obtained haemostasis on ovarian reserve, depending on haemostasis technique, applied after laparoscopic enucleation of endometrial cysts. Material and methods: Sixty-six female patients, at the age of 20-35 years, were included into the study. The diameters of the cystic lesions were within 40-70 mm. The patients were randomly assigned to two study groups. Group 1 involved patients after laparoscopic enucleation of ovarian cysts, in whom haemostasis was achieved by ovary suturing, while Group 2 included patients with haemostasis achieved by bipolar coagulation technique...
March 2018: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/29724534/low-anti-m%C3%A3-llerian-hormone-concentration-is-associated-with-increased-risk-of-embryonic-aneuploidy-in-women-of-advanced-age
#18
Xiao Jiang, Junhao Yan, Yan Sheng, Mei Sun, Linlin Cui, Zi-Jiang Chen
RESEARCH QUESTION: Does an association exist between serum anti-Müllerian hormone (AMH) level, the marker of biological ovarian age, and embryonic aneuploidy risk in recurrent spontaneous miscarriage (RSM) patients of reproductive age? DESIGN: This retrospective study included a total of 422 IVF cycles of 394 unexplained RSM patients undergoing preimplantation genetic testing for aneuploidy (PGT-A), enrolled from January 2014 to December 2016. Subjects were divided into three groups according to the 25th (1...
April 13, 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29724140/anti-m%C3%A3-llerian-hormone-levels-and-spontaneous-pregnancy-in-women-undergoing-surgery-for-benign-ovarian-cysts
#19
Luisa Casadei, Francesca Dominici, Doriana Scaldaferri, Veronica Vicomandi, Susanna Ciacci, Emilio Piccione
This prospective study had the objective to compare anti-Müllerian hormone (AMH) serum levels among women with endometriomas and those with other benign ovarian cysts and verify a possible correlation between the AMH post-operative decline and the achievement of pregnancy. The study included 57 women undergoing laparoscopic surgery. Serum levels of AMH were measured preoperatively and at 6 and 12 months postoperatively. AMH serum levels decreased in both endometriomas and other benign cysts, but significant recovery was reported only in endometriomas (p = ...
May 4, 2018: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29722946/-correlation-of-serum-anti-m%C3%A3-llerian-hormone-with-semen-parameters
#20
Long-Ping Peng, Yong Shao, Cen-Cen Wang, Zhi-Chuan Zou, Tao Shen, Li Chen, Bing Yao
Objective: To investigate the relationship between the serum anti-Müllerian hormone (AMH) level and semen parameters. METHODS: We collected the data about 726 outpatients at the Male Infertility Clinic of Jinling Hospital from September 2015 to November 2016, including 72 with non-obstructive azoospermia, 123 with oligospermia, and 531 with normal sperm concentration. We obtained the semen volume, total sperm count, sperm concentration, sperm motility, the percentages of progressively motile sperm (PMS) and morphologically normal sperm (MNS), and the levels of serum AMH, inhibin B (INH-B), total testosterone (TT) and follicle - stimulating hormone (FSH) of the patients, analyzed the correlation of the serum AMH level with the other parameters, and compared the AMH level among different groups...
June 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
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