Cerium

Metal oxide nanoparticles (MONP/s) induce DNA damage, which is influenced by their physicochemical properties. In this study, the high-throughput CometChip and micronucleus (MicroFlow) assays were used to investigate DNA and chromosomal damage in mouse lung epithelial cells induced by nano and bulk sizes of zinc oxide, copper oxide, manganese oxide, nickel oxide, aluminum oxide, cerium oxide, titanium dioxide, and iron oxide. Ionic forms of MONPs were also included. The study evaluated the impact of solubility, surface coating, and particle size on response...

Synthetic strategies to isolate molecular complexes of lanthanides, other than cerium, in the +4 oxidation state remain elusive, with only four complexes of Tb(iv) isolated so far. Herein, we present a new approach for the stabilization of Tb(iv) using a siloxide tripodal trianionic ligand, which allows the control of unwanted ligand rearrangements, while tuning the Ln(iii)/Ln(iv) redox-couple. The Ln(iii) complexes, [LnIII ((OSiPh2 Ar)3 -arene)(THF)3 ] (1-LnPh ) and [K(toluene){LnIII ((OSiPh2 Ar)3 -arene)(OSiPh3 )}] (2-LnPh ) (Ln = Ce, Tb, Pr), of the (HOSiPh2 Ar)3 -arene ligand were prepared...

The structural properties, dynamical behaviors, and ion transport phenomena at the interface between water and cerium oxide are investigated by reactive molecular dynamics (MD) simulations employing neural network potentials (NNPs). The NNPs are trained to reproduce density functional theory (DFT) results, and DFT-based MD (DFT-MD) simulations with enhanced sampling techniques and refinement schemes are employed to efficiently and systematically acquire training data that include diverse hydrogen-bonding configurations caused by proton hopping events...

Ceria nanoparticles (CeO2 NPs) have become popular materials in biomedical and industrial fields due to their potential applications in anti-oxidation, cancer therapy, photocatalytic degradation of pollutants, sensors, etc. Many methods, including gas phase, solid phase, liquid phase, and the newly proposed green synthesis method, have been reported for the synthesis of CeO2 NPs. Due to the wide application of CeO2 NPs, concerns about their adverse impacts on human health have been raised. This review covers recent studies on the biomedical applications of CeO2 NPs, including their use in the treatment of various diseases (e...

BACKGROUND AND PURPOSE: Neurotransmitters are chemical messengers that enhance and balance signals between cells and target cells in the body. They are vital to the body's ability to function. Epinephrine is one of the most essential catecholamine neurotransmitters with an important biological and pharmacological role in the mammalian central nervous system. Therefore, it is very important to develop sensitive, simple, and fast methods for the determination of this compound. EXPERIMENTAL APPROACH: In the present work, a glassy carbon electrode (GCE) modified with the cerium oxide-zinc oxide (CeO2 -ZnO) nanocomposite (CeO2 -ZnO/GCE) was developed for the sensitive and quick detection of epinephrine...

Cerium oxide nanoparticles (CeNPs) are versatile materials with unique and unusual properties that vary depending on their surface chemistry, size, shape, coating, oxidation states, crystallinity, dopant, and structural and surface defects. This review encompasses advances made over the past twenty years in the development of CeNPs and ceria-based nanostructures, the structural determinants affecting their activity, and translation of these distinct features into applications. The two oxidation states of nanosized CeNPs (Ce3+ /Ce4+ ) coexisting at the nanoscale level facilitate the formation of oxygen vacancies and defect states, which confer extremely high reactivity and oxygen buffering capacity and the ability to act as catalysts for oxidation and reduction reactions...

An efficient and scalable method for the synthesis of 3,4-dihydroisoquinolin-1(2 H )-ones through benzylic oxidation of tetrahydroisoquinoline derivatives using a catalytic amount of cerium ammonium nitrate (CAN) and a stoichiometric amount of NaBrO3 as oxidants was developed. The reaction is significantly influenced by the substituent groups on the phenyl ring. While electron-withdrawing groups on the phenyl ring can lower the reactivities of the substrates, electron-donating groups on the phenyl ring can dramatically promote the oxidation rate...

A convenient self-assembly method is proposed for synthesis of 3D Au/MOF-808 (Zr) composite nanostructures with a cerium metal-organic framework loaded with gold nanoparticles. We combine adsorption properties of MOF materials with surface plasmon resonance of noble metals to construct hotspot-dense 3D Au/MOF-808 (Zr) SERS substrates, by using a two-step method of solvothermal and reduction reactions. The results show that optimal SERS substrates are obtained from a volume ratio of gold nanoparticles to MOF-808 (Zr) solution of 4:1 and a self-assembly time of 2 h...

PURPOSE: The radionuclide pair cerium-134/lanthanum-134 ( 134 Ce/ 134 La) was recently proposed as a suitable diagnostic counterpart for the therapeutic alpha-emitter actinium-225 ( 225 Ac). The unique properties of 134 Ce offer perspectives for developing innovative in vivo investigations not possible with 225 Ac. In this work, 225 Ac- and 134 Ce-labeled tracers were directly compared using internalizing and slow-internalizing cancer models to evaluate their in vivo comparability, progeny meandering, and potential as a matched theranostic pair for clinical translation...

Wound infection caused by multidrug-resistant bacteria poses a serious threat to antibiotic therapy. Therefore, it is of vital importance to find new methods and modes for antibacterial therapy. The cerium nitrogen co-doped titanium dioxide nanoparticles (N-TiO2 , 0.05Ce-N-TiO2 , 0.1Ce-N-TiO2 , and 0.2Ce-N-TiO2 ) were synthesized using the hydrothermal method in this study. Subsequently, electrospinning was employed to fabricate polylactic acid (PLA) electrospun membranes loaded with the above-mentioned nanoparticles (PLA-N, PLA-0...

Inflammatory responses, especially chronic inflammation, are closely associated with many systemic diseases. There are many ways to treat and alleviate inflammation, but how to solve this problem at the molecular level has always been a hot topic in research. The use of nanoparticles (NPs) as anti-inflammatory agents is a potential treatment method. We synthesized new hollow cerium oxide nanomaterials (h CeO2 NPs) doped with different concentrations of Cu5.4 O NPs [the molar ratio of Cu/(Ce + Cu) was 50%, 67%, and 83%, respectively], characterized their surface morphology and physicochemical properties, and screened the safe concentration of h CeO2 @Cu5...

In this study, a novel Ce2 MgMoO6 /CNFs (cerium magnesium molybdite double perovskites decorated on carbon nanofibers) nanocomposite was developed for selective and ultra-sensitive detection of ciprofloxacin (CFX). Physical characterization and analytical techniques were used to explore the morphology, structure, and electrocatalytic characteristics of the Ce2 MgMoO6 /CNFs nanocomposite. The sensor has a wide linear range (0.005 to 7.71 μM and 9.75 to 77.71 μM), a low limit of detection (0.012 μM), high sensitivity (0...

Agricultural soils are increasingly undergoing inadvertent and purposeful exposures to engineered CeO2 nanoparticles (NPs), which can impact crops and root-associated microbial communities. However, interactions between NP concentration and exposure duration on plant-mediated responses of root-associated bacterial communities are not well understood. Soybeans seedlings were grown in soil with uncoated NPs added at concentrations of 0, 1 or 100 mg kg-1 . Total soil exposure durations were either 190 days, starting 106 days before planting or 84 days with NP amendments coinciding with planting...

Ce4+ cations are commonly used as electron acceptors during the water oxidation to O2 reaction over Ir- and Ru-based catalysts. They can also be reduced to Ce3+ cations by excited electrons from the conduction band of an oxide semiconductor with a suitable energy level. In this work, we have studied their interaction with rutile TiO2(110) single crystal upon band gap excitation by femtosecond transient absorption spectroscopy (TAS) in solution in the 350-900 nm range and up to 3.5 ns. Unlike excitation in the presence of water alone the addition of Ce4+ resulted in a clear ground-state bleaching (GSB) signal at the band gap energy of TiO2 (ca...

CONTEXT: Depletion of natural resources, responsible for energy production, is a serious concern for researchers to develop alternate energy resources or materials. Scientists have proposed various energy materials which are based on semiconductors and their underlying physics. Cerium oxide (CeO2 ) is a versatile energy material which receives much attention owing to excellent photocatalytic, photonic, thermal stability, and optoelectronic applications. Even though CeO2 exhibited remarkable physical properties, but yet, they can be enhanced upon suitable doping...

Engineered nanoparticles (ENPs) have been increasingly used in agricultural operations, leading to an urgent need for robust methods to analyze co-occurring ENPs in plant tissues. In response, this study advanced the simultaneous extraction of coexisting silver, cerium oxide, and copper oxide ENPs in lettuce shoots and roots using macerozyme R-10 and analyzed them by single-particle inductively coupled plasma-mass spectrometry (ICP-MS). Additionally, the standard stock suspensions of the ENPs were stabilized with citrate, and the long-term stability (up to 5 months) was examined for the first time...

The efficacy of traditional radiotherapy (RT) has been severely limited by its significant side effects, as well as tumor hypoxia. Here, the nanoscale cerium (Ce)-based metaloxo clusters (Ce(IV)6 )-porphyrin (meso-tetra (4-carboxyphenyl) porphyrin, TCPP) framework loaded with L-arginine (LA) (denoted as LA@Ce(IV)6 -TCPP) is developed to serve as a multifarious radio enhancer to heighten X-ray absorption and energy transfer accompanied by O2 /NO generation for hypoxia-improved RT-radiodynamic therapy (RDT) and gas therapy...

Metal-oxide nanocomposites (MONs) are of pivotal importance as electrode materials, yet lack a guiding principle to tune their phase texture. Here we report that the phase texture of MONs can be tuned at the nanoscale by controlling the nanophase separation of precursor alloys. In situ transmission electron microscopy ( in situ TEM) has demonstrated that a MON material of platinum (Pt) and cerium oxide (CeO2 ) is obtained through promoted nanophase separation of a Pt5 Ce precursor alloy in an atmosphere containing oxygen (O2 ) and carbon monoxide (CO)...

The need for tumor postoperative treatments aimed at recurrence prevention and tissue regeneration have raised wide considerations in the context of the design and functionalization of implants. Herein, an injectable hydrogel system encapsulated with anti-tumor, anti-oxidant dual functional nanoparticles has been developed in order to prevent tumor relapse after surgery and promote wound repair. The utilization of biocompatible gelatin methacryloyl (GelMA) was geared towards localized therapeutic intervention...

BACKGROUND: Microcystin-leucine-arginine (MC-LR) produced by various cyanobacteria during harmful algal bloom poses serious threats to drinking water safety and human health. Conventional chromatography-based detection methods require expensive instruments and complicated sample pretreatment, limiting their application for on-site detection. Colorimetric aptasensors are simple and rapid, and are amenable to fast detection. However, they provide only one output signal, resulting in poor sensitivity and accuracy...