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https://www.readbyqxmd.com/read/28728295/-effect-of-21-gene-recurrence-score-on-chemotherapy-decisions-for-patients-with-estrogen-receptor-positive-epidermal-growth-factor-receptor-2-negative-and-lymph-node-negative-early-stage-breast-cancer
#1
Y Mao, X S Chen, Y Liang, J Y Wu, O Huang, Y Zong, Q Fang, J R He, L Zhu, W G Chen, Y F Li, L Lin, X C Fei, K W Shen
Objective: To investigate the effect of 21-gene recurrence score on adjuvant chemotherapy decisions for patients with estrogen receptor (ER)-positive, epidermal growth factor receptor 2 (HER-2)-negative and lymph node (LN)-negative early stage-breast cancer. Methods: One hundred and forty-eight patients with ER+ , HER-2- and LN- early stage breast cancer were recruited in the Ruijin hospital, Shanghai Jiao Tong University School of Medicine. The 21-gene recurrence score (RS)assay was performed and systemic therapeutic decisions were made before and after knowing the RS results under multidisciplinary discussion...
July 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28728281/-a-cross-sectional-study-of-cataract-in-residents-with-type-2-diabetes-living-in-xinjing-town-shanghai
#2
B J Zhu, X R Zou, Y Xu, X L Bai, M Lu, Y Y Ma, L N Lu, J F Zhu, H D Zou, X Xu
Objective: To investigate the prevalence, subtypes and risk factors of cataract in type 2 diabetic individuals. Methods: Geographically defined cluster sampling method was used in this population-based, cross-sectional study. There were 7 756 type 2 diabetes individuals in Xinjing Town with a residential population of 88 864. The type 2 diabetic individuals were randomly selected from 20 basic sample units in Xinjing Town of Changning District from April to June 2016. All participants received visual acuity measurement and eye examination...
July 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28728265/-mass-spectrometry-combined-with-gene-analysis-for-prenatal-diagnosis-of-glutaric-acidemia-type-%C3%A2
#3
F Han, L S Han, W J Ji, T Chen, F Xu, Y Wang, J Ye, W J Qiu, H W Zhang, Y Z Jiang, C Hou, X F Gu
Objective: To investigate the value of amniotic fluid metabolite detection by mass spectrometry combined with gene mutation analysis in the prenatal diagnosis of glutaric acidemia type Ⅰ (GA-Ⅰ). Method: From January 2009 to December 2016, Department of Pediatric Endocrinology and Genetic, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine carried out prenatal diagnosis for 24 cases of pregnant women with GA-Ⅰproband. 24 pregnant women without organic acidemia proband for conventional prenatal diagnosis at the same period were used as the control group...
July 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28728263/-identification-of-mutations-associated-with-coronary-artery-lesion-susceptibility-in-kawasaki-disease-by-targeted-enrichment-of-genomic-region-sequencing-technique
#4
D Y Zhu, S R Song, L J Xie, F Qiu, J Yang, T T Xiao, M Huang
Objective: To screen and identify the mutations in Kawasaki disease by targeted enrichment of genomic region sequencing technique and investigate susceptibility genes associated with coronary artery lesion. Method: This was a case-control study.A total of 114 patients diagnosed as Kawasaki disease treated in Shanghai Children's Hospital between December 2015 and November 2016 were studied and another 45 healthy children who were physically examined in outpatient department were enrolled as control group. Patients were divided into two groups based on the results of echocardiogram...
July 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28728260/-clinical-analysis-of-pacing-therapy-and-treatment-of-complications-during-follow-up-in-children
#5
P J Zhao, Y W Chen, F Li, Y Li, J P Yang, J J Wu
Objective: To analyze characteristics of permanent pacemaker implantation in children as well as treatment and prognosis of complications. Method: Clinical data of children who underwent endocardial or epicardial permanent pacemaker implantation between April 2000 and June 2016 in Shanghai Xinhua Hospital and Shanghai Children's Medical Center were analyzed retrospectively. These patients were discharged 5 days after implantation. Electrocardiogram, chest X ray, echocardiography and pacemaker programming were performed during follow-up...
July 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28728259/-impact-of-allergic-airway-diseases-on-risk-of-attention-deficit-hyperactivity-disorder-in-school-age-children
#6
X D Jiang, C Shen, K Li, Y T Ji, S H Li, F Jiang, X M Shen, F Li, Y Hu
Objective: To investigate the impact of allergic airway diseases on the risk of attention deficit hyperactivity disorder (ADHD) in school-age children. Method: Used stratified cluster sampling method, school-age children in first to sixth grade in primary schools in 9 randomly selected cities including Shanghai, Guangzhou, Xi'an, and Wuhan were enrolled in the study. Interview of parents with questionnaires, which included school-age individual and family social environment questionnaire (including history of diagnosed ADHD, allergic rhinitis, and bronchial asthma) and Children's Sleep Habits Questionnaire (CSHQ), were finished and collected during November to December in 2005...
July 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28728243/-the-treatment-effect-of-eustachian-tube-atresia-with-laser-and-connical-plastic-tube-after-radiotherapy-for-nasopharyngeal-carcinoma
#7
H G Gao, J Tong, W W Chen
Objective: To investigate the method in treatment of Eustschian tube atresia caused by radiotherapy. Methods: Two cases diagnosed of Eustschian tube atresia following radiotherapy were retrospectively analyzed in Department of Otorhinolaryngology, Divided Hospital of Shanghai University Communication Affiliated First People Hospital in Apr. 2014 and Oct. 2015. Both cases were female, 65 and 64 years old, and accepted radiotherapy six and 20 years ago respectively. The pharyngeal orifices of Eustschian tube were found to be totally closed under endoscope...
July 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28723745/evaluation-of-the-predictive-value-of-red-blood-cell-distribution-width-for-onset-of-cerebral-infarction-in-the-patients-with-obstructive-sleep-apnea-hypopnea-syndrome
#8
Chang-Xing Shen, Min Tan, Xiao-Lian Song, Shuan-Shuan Xie, Guo-Liang Zhang, Chang-Hui Wang
Red blood cell distribution width (RDW) is a risk factor for the complications caused by obstructive sleep apnea hypopnea syndrome (OSAHS). This study was aimed to evaluate the predictive value of RDW for the occurrence of cerebral infarction in patients with OSAHS.We conducted a prospective study of 129 consecutive patients who were admitted to the Sleep Laboratory of in the Tenth People's Hospital of Shanghai (China) with complaints of snoring, apnea, or daytime sleepiness. All patients underwent polysomnography between June 2011 and May 2012...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28722697/bifid-mandibular-canals-incidence-and-anatomical-variations-in-the-population-of-shanghai-area-by-cone-beam-computed-tomography
#9
Xiaoli Yang, Chengqi Lyu, Derong Zou
OBJECTIVE: The aim of this study was to analyze the rate, location, and characteristics of bifid mandibular canals (BMCs) in the population of the Shanghai area using cone beam computed tomography to avoid complications during surgical procedures. METHODS: Two hundred eighty patients were recruited for this study, and the presence and morphology of BMCs were evaluated. RESULTS: The occurrence rate of BMCs in the Shanghai area was relatively high compared with that in other populations, reaching 31...
July 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28722093/-a-multicenter-randomized-controlled-trial-of-wheat-cellulose-particles-in-the-treatment-of-internal-hemorrhoids
#10
Yunhua Peng, Wei Yang, Yehuang Wang, Xiaohua Fan, Xueping Zheng, Juanjuan Gai
OBJECTIVE: To evaluate the efficacy and safety of wheat cellulose particles (testa triticum tricum purify, Fiberform) in the treatment of internal hemorrhoid. METHODS: A multicenter randomized controlled clinical trial was adopted. From October 2015 to July 2016, 60 patients with internal hemorrhoid were enrolled from three medical centers, including Department of Anorectum, Shuguang Hospital of Shanghai University of Traditional Chinese Medicine, Department of Anorectum, The Third Affiliated Hospital of Nanjing University of Chinese Medicine, Department of Anorectum, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine...
July 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28719279/clinical-characteristics-and-prognosis-of-penicilliosis-among-human-immunodeficiency-virus-infected-patients-in-eastern-china
#11
Jun Chen, Renfang Zhang, Yinzhong Shen, Li Liu, Tangkai Qi, Zhenyan Wang, Wei Song, Yang Tang, Hongzhou Lu
AbstractTalaromyces marneffei infection is increasingly observed in people living with human immunodeficiency virus (HIV) in eastern China, a nonendemic area. This study aimed to draw the clinician's attention to this disease by presenting the clinical characteristics and prognosis of penicilliosis among HIV-infected patients from this region. We retrospectively analyzed HIV-infected patients with culture-proven T. marneffei infection admitted during January 1, 2014-December 31, 2015, at the Shanghai Public Health Clinical Center...
June 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28718158/the-extent-of-heavy-metal-pollution-and-their-potential-health-risk-in-topsoils-of-the-massively-urbanized-district-of-shanghai
#12
Syed Taseer Abbas Jaffar, Long-Zhu Chen, Hassan Younas
Urbanization and industrialization increase the concentrations of heavy metals in soils, which affect human health. A total of 127 topsoil samples were collected from the massively urbanized and industrialized district of Shanghai: Baoshan District. The sampling sites were isolated based on the land-use practice: industrial area, roadside area, residential area, and agricultural area. The absolute concentrations of heavy metals (Zn, Cr, Ni, Mn, Cu, Pb, and Cd) were determined using atomic absorption spectrometry and compared with Shanghai and the National soil background values...
July 17, 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28711905/the-prevalence-subtypes-and-associated-factors-of-hyperuricemia-in-lupus-nephritis-patients-at-chronic-kidney-disease-stages-1-3
#13
Simeng Liu, Yijun Gong, Hong Ren, Wen Zhang, Xiaonong Chen, Tong Zhou, Xiao Li, Nan Chen
There is a high prevalence of hyperuricemia (HUA) in the chronic kidney disease (CKD) population. However, there's a dearth of research on HUA's prevalence, subtypes, early detection, and treatment strategies of HUA in lupus nephritis (LN) patients. The aim of this study is to address these knowledge gaps. LN patients presenting to the Department of Nephrology at Shanghai Rui Jin Hospital from January 2011 to January 2016 were recruited. The effective sample size was derived using the power analysis. The demographic, clinical and laboratory characteristics of the LN patients with HUA were compared with those of patients without HUA...
July 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/28711824/atmospheric-bulk-deposition-of-polycyclic-aromatic-hydrocarbons-in-shanghai-temporal-and-spatial-variation-and-global-comparison
#14
Daolun Feng, Ying Liu, Yi Gao, Jinxing Zhou, Lirong Zheng, Gang Qiao, Liming Ma, Zhifen Lin, Peter Grathwohl
Atmospheric deposition leads to accumulation of atmospheric polycyclic aromatic hydrocarbons (PAHs) on urban surfaces and topsoils. To capture the inherent variability of atmospheric deposition of PAHs in Shanghai's urban agglomeration, 85 atmospheric bulk deposition samples and 7 surface soil samples were collected from seven sampling locations during 2012-2014. Total fluxes of 17 PAHs were 587-32,300 ng m(-2) day(-1), with a geometric mean of 2600 ng m(-2) day(-1). The deposition fluxes were categorized as moderate to high on a global scale...
July 13, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28710911/a-novel-technique-for-reduction-malarplasty-by-inward-displacement-of-infractured-zygomatic-arch-without-fixation
#15
Qingfeng Li, Bowen Gao, Ke Li, Feng Xie, Hainan Zhu, Liang-Gang Yu
PURPOSE: Reduction malarplasty is one of the most common esthetic surgical procedures performed in the Asian population. Traditional procedures have several complications, such as bone nonunion, malunion, cheek drooping, and damage to the infraorbital nerve and maxillary sinus. Therefore, a more straightforward and effective method of reducing the width of the midface is needed. In this study, we introduce an infracture technique using inward displacement of the zygomatic arch without fixation...
June 24, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28708426/phenotypic-characteristics-and-genetic-diversity-of-salmonella-enterica-serotype-derby-isolated-from-human-patients-and-foods-of-animal-origin
#16
Chenggang Xu, Xingxing Ren, Zhou Feng, Ying Fu, Yanfen Hong, Zujie Shen, Lina Zhang, Ming Liao, Xuebin Xu, Jianmin Zhang
Salmonella enterica serotype Derby is among the three most common serotypes of nontyphoidal Salmonella isolated from patients with diarrhea in China. In this study, 133 Salmonella Derby isolates from human patients (n = 74) and foods of animal origin (n = 59) in Shanghai, China, between September 2013 and December 2014, were selected to study its phenotypic characteristics and genetic diversity. The isolates were subjected to antimicrobial susceptibility testing, plasmid replicon typing, virulence profile determination, and molecular subtyping by pulsed-field gel electrophoresis (PFGE)...
July 14, 2017: Foodborne Pathogens and Disease
https://www.readbyqxmd.com/read/28707707/evidence-for-capitation-reform-in-a-new-rural-cooperative-medical-scheme-in-pudong-new-area-shanghai-a-longitudinal-study
#17
Yanmei Wang, Zhiqun Shu, Jianjun Gu, Xiaoming Sun, Limei Jing, Jie Bai, Xuan Huang, Jiquan Lou, Qunfang Zhang, Ming Li
Currently, China has been experiencing rapid growth of medical costs, serious waste of medical resources, increasing disease burden for residents, and a medical insurance fund deficit. Therefore, an urgent problem that needs to be solved is to choose a rational payment for the insurance system. To empirically evaluate the long-term effects of capitation reform in a New Rural Cooperative Medical Scheme in Pudong New Area, we collected and analysed data regarding financing, fund operation, medical service cost, and medical care-seeking behaviour from 2011 to 2015, a duration that includes data before and after reform...
July 14, 2017: International Journal of Health Planning and Management
https://www.readbyqxmd.com/read/28706246/combined-impact-of-known-lifestyle-factors-on-total-and-cause-specific-mortality-among-chinese-men-a-prospective-cohort-study
#18
Qing-Li Zhang, Long-Gang Zhao, Wei Zhang, Hong-Lan Li, Jing Gao, Li-Hua Han, Wei Zheng, Xiao-Ou Shu, Yong-Bing Xiang
Impact of combined lifestyles on risk of mortality needs to be explored quantitatively. We aimed to evaluate the associations of combined lifestyle factors with total and cause-specific mortality in Chinese men. We used data from the Shanghai Men's Health Study (2002-2013), an on-going population-based prospective cohort study of men (aged 40 to 74 years). Four traditional unfavorable lifestyle factors were included: smoking, heavy alcohol use, unhealthy diet and physical inactivity. Cox proportional hazards models were used to calculate the hazard ratios (HRs) and 95% confidence intervals (CIs)...
July 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28702917/occurrence-and-risk-assessment-of-antidepressants-in-huangpu-river-of-shanghai-china
#19
Minghong Wu, Jiajia Xiang, Fenfen Chen, Cao Fu, Gang Xu
Antidepressants are gaining public attention because of increasing reports of their occurrence in environment and their potential impact on ecosystems and human health. Continuous input of pharmaceuticals into rivers, through psychiatric hospital or wastewater treatment plant (WWTPs) effluent, may cause adverse effects on the aquatic ecosystems of the receiving water bodies. This work investigates the occurrence and sources of 8 antidepressants in main stream and tributaries of Huangpu River in Shanghai. The detected concentrations of the selected antidepressants ranged from low nanogram per liter to 42...
July 13, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28700089/prevalence-and-genotype-distribution-of-human-papillomavirus-among-females-in-the-suburb-of-shanghai-china
#20
Chengzhong Zhang, Chao Zhang, Jie Huang, Zhouwei Wu, Xingyu Mei, Weimin Shi
OBJECTIVES: To describe the prevalence of human papillomavirus (HPV) and its genotype distribution among females in the suburb of Shanghai. METHODS: A total of 33,562 participants were enrolled in this study from January to December 2016. HPV GenoArray test kit was used to perform HPV genotyping and was also used in DNA amplification and HybriBio's proprietary flow-through hybridization technique. RESULTS: The overall prevalence of HPV was 18...
July 12, 2017: Journal of Medical Virology
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