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https://www.readbyqxmd.com/read/28645522/acute-effects-of-ambient-temperature-and-particulate-air-pollution-on-fractional-exhaled-nitric-oxide-a-panel-study-among-diabetic-patients-in-shanghai-china
#1
Huichu Li, Hongjian Bai, Changyuan Yang, Renjie Chen, Cuicui Wang, Zhuohui Zhao, Haidong Kan
BACKGROUND: Epidemiological studies have shown the associations of ambient temperature and particulate matter (PM) air pollution with respiratory morbidity and mortality. However, the underlying mechanisms have not been well characterized. The aim of this study is to investigate the associations of temperature and fine and coarse PM with fractional exhaled nitric oxide (FeNO), a well-established biomarker of respiratory inflammation. METHODS: We conducted a longitudinal panel study involving six repeated FeNO tests among 33 type 2 diabetes mellitus patients from April to June 2013 in Shanghai, China...
June 20, 2017: Journal of Epidemiology
https://www.readbyqxmd.com/read/28643309/-comparison-of-clinicopathological-features-and-prognosis-between-left-sided-colon-cancer-and-right-sided-colon-cancer
#2
Xianhua Gao, Guanyu Yu, Peng Liu, Liqiang Hao, Lianjie Liu, Wei Zhang
OBJECTIVE: To compare the clinicopathological features and prognosis between left-sided colon cancer (LC) and right-sided colon cancer (RC). METHODS: Clinicopathological and follow-up data of 2 174 colon carcinoma cases undergoing resection at Shanghai Changhai Hospital of The Second Military Medical University from January 2000 to December 2010 were retrospectively analyzed. Patients with transverse colon cancer, overlapping position, unknown location, recurrent cancer, multiple primary cancer, concomitant malignant tumors, preoperative chemotherapy, local resection, incomplete clinical data and missed follow up were excluded...
June 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28642752/a-comprehensive-epidemiological-research-for-clinical-vibrio-parahaemolyticus-in-shanghai
#3
Huan Li, Rong Tang, Yang Lou, Zelin Cui, Wenjing Chen, Qing Hong, Zhaohuan Zhang, Pradeep K Malakar, Yingjie Pan, Yong Zhao
Vibrio parahaemolyticus is one of the most important pathogen for seafood-borne gastroenteritis in Shanghai and the rest of the world. A total of 42 V. parahaemolyticus strains were isolated from 1900 fecal specimens collected from patients in Shanghai hospital presenting from January 2014 to December 2015. All isolates were evaluated for potential virulence factors [tdh, trh, and type three secretion system (T3SS) genes], typed using multilocus sequence typing (MLST) and screened for antimicrobial resistance phenotype and genotype...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28642011/comparison-of-indian-council-for-medical-research-and-lunar-databases-for-categorization-of-male-bone-mineral-density
#4
Surya K Singh, Vivek Patel, Balram Gupta
The mainstay of diagnosis of osteoporosis is dual-energy X-ray absorptiometry (DXA) scan measuring areal bone mineral density (BMD) (g/cm(2)). The aim of the present study was to compare the Indian Council of Medical Research database (ICMRD) and the Lunar ethnic reference database of DXA scans in the diagnosis of osteoporosis in male patients. In this retrospective study, all male patients who underwent a DXA scan were included. The areal BMD (g/cm(2)) was measured at either the lumbar spine (L1-L4) or the total hip using the Lunar DXA machine (software version 8...
June 19, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28640919/the-measles-epidemic-trend-over-the-past-30-years-in-a-central-district-in-shanghai-china
#5
Jie Gao, Bing Shen, JianJing Xiong, Yihan Lu, Qingwu Jiang
BACKGROUND: Measles vaccination over the past 50 years has greatly reduced the incidence of measles. However, measles among migrants and the resulting changes in epidemiological characteristics have brought new challenges to the elimination of measles. We aim to describe the measles epidemic trend over the past 30 years in a central district in Shanghai, China. METHODS: The present study was conducted in the Jing'an District, which is located in the center of Shanghai...
2017: PloS One
https://www.readbyqxmd.com/read/28640137/china-s-growing-contribution-to-sepsis-research-from-1984-to-2014-a-bibliometric-study
#6
Kai Zhang, Jialian Zhao, Lihua Chu, Yue Jin, Baoli Cheng, Guohao Xie, Yan Wang, Xiangming Fang
BACKGROUND: The aim of this study was to analyze the global trends of sepsis research and investigate China's contribution by comparing the quantity and quality of sepsis-related publications. METHODS: Sepsis-related publications were main retrieved from the Web of Science online database by using the keywords "sepsis" or "septic shock." Bibliometric indicators, including the number of publications, total citation frequency, citation frequency per paper, h-index, research type, orientation, organization, author, journal, and funding support were analyzed...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28639910/apatinib-for-metastatic-breast-cancer-in-non-clinical-trial-setting-satisfying-efficacy-regardless-of-previous-anti-angiogenic-treatment
#7
Ying Lin, Zheng Wu, Jian Zhang, Xichun Hu, Zhonghua Wang, Biyun Wang, Jun Cao, Leiping Wang
Apatinib is a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor receptor 2. This study aimed to evaluate the efficacy and safety of apatinib in metastatic breast cancer (MBC) under non-clinical trial setting, and to study the impact of previous antiangiogenic treatment to the efficacy of apatinib. 52 MBC patients treated with apatinib under non-clinical trial setting in Fudan University Shanghai Cancer Center between January 1st 2015 and October 1st 2016 were included. All patients were included in time-to-treatment failure (TTF) analysis, while 45 patients were enrolled for progression-free survival (PFS) and overall survival (OS) analysis because 7 of the patients with treatment discontinuation due to intolerable toxicities had too short time for efficacy assessment...
June 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/28637292/ten-year-real-life-effectiveness-of-coronary-artery-bypass-using-radial-artery-or-great-saphenous-vein-grafts-in-a-single-centre-chinese-hospital
#8
Yunpeng Zhu, Anqing Chen, Zhe Wang, Jun Liu, Junfeng Cai, Mi Zhou, Qiang Zhao
OBJECTIVES: Long-term effectiveness of coronary artery bypass grafting using radial artery (RA) or great saphenous vein (SVG) grafts as a second conduit was compared. METHODS: Patients received simple elective off-pump coronary artery bypass involving both the left internal thoracic artery (LITA) and the left anterior descending artery between January 1999 and December 2005 at Ruijin Hospital, Shanghai Jiaotong University School of Medicine, China. RA graft patients ( n  = 147 LITA + RA and n  = 61 LITA + RA + SVG) were matched with SVG graft patients ( n  = 208 LITA + SVG)...
June 16, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28636977/long-term-trend-of-o3-in-a-mega-city-shanghai-china-characteristics-causes-and-interactions-with-precursors
#9
Wei Gao, Xuexi Tie, Jianming Xu, Rujin Huang, Xiaoqing Mao, Guangqiang Zhou, Luyu Chang
In recent years, ozone (O3) is often the major pollutant during summertime in China. In order to better understand this problem, a long-term measurement of ozone (from 2006 to 2015) and its precursors (NOx and VOCs) as well as the photochemical parameter (UV radiation) in a mega city of China (Shanghai) is analyzed. The focus of this study is to investigate the trend of O3 and the causes of the O3 trend in large cities in China. In order to understand the relationship between the O3 precursors and O3 formation, two distinguished different sites of measurements are selected in the study, including an urbanization site (XJH-Xujiahui) and a remote site (DT-Dongtan)...
June 18, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28625235/-pharmacokinetics-of-vancomycin-in-patients-with-severe-acute-pancreatitis-and-its-influencing-factors-analysis-of-7-years-data
#10
Juan He, Enqiang Mao, Feng Jing, Huiting Jiang, Wanhua Yang, Erzhen Chen
OBJECTIVE: To observe the change of the serum trough concentration and its pharmacokinetics of vancomycin in patients with severe acute pancreatitis (SAP), and to analyze the factors influencing vancomycin concentration. METHODS: A retrospective analysis was conducted. Steady-state trough concentrations of vancomycin from patients (18-80 years old) with SAP concomitantly with G(+) infection admitted to Intensive Care Unit (ICU) of Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine from January 2010 to December 2016 were enrolled...
June 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28623830/identification-characteristics-and-human-exposure-assessments-of-triclosan-bisphenol-a-and-four-commonly-used-organic-uv-filters-in-indoor-dust-collected-from-shanghai-china
#11
Junjie Ao, Tao Yuan, Yuning Ma, Li Gao, Ni Ni, Dan Li
Indoor dust is a very significant medium to understand human exposure of emerging contaminants. A novel and robust analytical method to measure the amounts of six personal care products (PCPs) (triclosan, bisphenol-A and four commonly used organic ultraviolet (UV) filters) simultaneously in indoor dust is developed in this paper. Target analytes were extracted using accelerated solvent extraction. After sample cleanup by solid-phase extraction (SPE), the extracts were derivatized and analyzed using gas chromatography-tandem mass spectrometry...
June 9, 2017: Chemosphere
https://www.readbyqxmd.com/read/28623330/assessing-spatial-and-temporal-patterns-of-observed-ground-level-ozone-in-china
#12
Wan-Nan Wang, Tian-Hai Cheng, Xing-Fa Gu, Hao Chen, Hong Guo, Ying Wang, Fang-Wen Bao, Shuai-Yi Shi, Bin-Ren Xu, Xin Zuo, Can Meng, Xiao-Chuan Zhang
Elevated ground-level ozone (O3), which is an important aspect of air quality related to public health, has been causing increasing concern. This study investigated the spatiotemporal distribution of ground-level O3 concentrations in China using a dataset from the Chinese national air quality monitoring network during 2013-2015. This research analyzed the diurnal, monthly and yearly variation of O3 concentrations in both sparsely and densely populated regions. In particular, 6 major Chinese cities were selected to allow a discussion of variations in O3 levels in detail, Beijing, Chengdu, Guangzhou, Lanzhou, Shanghai, and Urumchi, located on both sides of the Heihe-Tengchong line...
June 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28621946/the-acute-effects-of-fine-particulate-matter-constituents-on-blood-inflammation-and-coagulation
#13
Cong Liu, Jing Cai, Renjie Chen, Liping Qiao, Hongli Wang, Wenxi Xu, Huichu Li, Zhuohui Zhao, Haidong Kan
Limited evidence is available on the effects of various fine particulate matter (PM2.5) constituents on blood inflammation and coagulation. We examined the associations between 10 constituents and 10 circulating biomarkers in a panel of 28 urban residents with 4 repeated measurements in Shanghai, China. Based on the linear mixed-effect models, we fitted the single-constituent models, the constituent-PM2.5 joint models, and the constituent-residual models to evaluate the associations between PM2.5 constituents and 8 inflammatory biomarkers (fibrinogen, C-reactive protein, monocyte chemoattractant protein-1, tumor necrosis factor-α, interleukin-1b, intercellular adhesion molecule-1, P-selectin, vascular cell adhesion molecule-1) and 2 coagulation biomarkers (plasminogen activator inhibitor-1 and soluble CD40 ligand)...
June 16, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28619403/practice-knowledge-and-barriers-for-screening-of-hepatocellular-carcinoma-among-high-risk-chinese-patients
#14
Kerui Xu, Shinobu Watanabe-Galloway, Fedja A Rochling, Jianjun Zhang, Paraskevi A Farazi, Hongyan Peng, Hongmei Wang, Jiangtao Luo
BACKGROUND: Hepatocellular carcinoma (HCC) is among the leading causes of cancer deaths in China. Considering its poor prognosis when diagnosed late, Chinese guidelines recommend biannual screening for HCC with abdominal ultrasound and serum α-fetoprotein (AFP) test for high-risk populations. OBJECTIVES: To investigate the practice, knowledge, and self-perceived barriers for HCC screening among high-risk hospital patients in China. METHODS: An interview-based questionnaire was conducted among Chinese patients with chronic hepatitis B and/or chronic hepatitis C infection from outpatient clinics at 2 tertiary medical institutions in Shanghai and Wuhan, China...
March 2017: Annals of Global Health
https://www.readbyqxmd.com/read/28619172/genetic-analysis-of-salmonella-enterica-serovar-gallinarum-biovar-pullorum-based-on-characterization-and-evolution-of-crispr-sequence
#15
Xiaolei Xie, Yachen Hu, Yaohui Xu, Kequan Yin, Yang Li, Yun Chen, Jie Xia, Lijuan Xu, Zijian Liu, Shizhong Geng, Qiuchun Li, Xinan Jiao, Xiang Chen, Zhiming Pan
Salmonella enterica serovar Gallinarum biovar Pullorum (S. Pullorum) is the cause of pullorum disease, characterized by white diarrhea, which leads to high mortality in poultry. In this study, we aimed to assess the genetic diversity of 655 S. Pullorum strains from 1962 to 2015 in China, Europe, and South America. A sequence typing scheme based on clustered regularly interspaced short palindromic repeats (CRISPR) was used to reveal the genetic relationships among these strains in this study. Overall, a total of 20 Pullorum sequence types (PSTs) of CRISPR were identified in the 655 isolates with PST7 (74%, 486/655) and PST3 (13%, 86/655) to be the most two frequent PSTs belonging to two different lineages, which confirmed the genetic conservation of S...
May 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28619034/evaluation-of-two-intervention-models-on-contraceptive-attitudes-and-behaviors-among-nulliparous-women-in-shanghai-china-a-clustered-randomized-controlled-trial
#16
Yuan He, Ning Zhang, Jue Wang, Na He, Yan Du, Jing-Xin Ding, Ying Zhang, Xiao-Tian Li, Jian Huang, Ke-Qin Hua
BACKGROUND: With increasing acceptance of premarital sex among young Chinese women, the rates of unintended pregnancies and induced abortions are becoming alarmingly high, suggesting the needs of educating women with adequate contraceptive knowledge and providing them with accessible contraceptive services. Previous studies have shown that knowledge and attitudes towards contraception could be modified through intervention strategies. This study aimed to evaluate the effects of two community intervention models on modifying contraceptive attitudes and behaviors among nulliparous women...
June 15, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28616702/the-indication-of-completion-lobectomy-for-lung-adenocarcinoma-%C3%A2-3%C3%A2-cm-after-wedge-resection-during-surgical-operation
#17
Yiyang Wang, Rui Wang, Difan Zheng, Baohui Han, Jie Zhang, Heng Zhao, Jizhuang Luo, Jiajie Zheng, Tianxiang Chen, Qingyuan Huang, Yihua Sun, Haiquan Chen
PURPOSE: This retrospective study was designed to find out the potential indications of completion lobectomy (CL) during wedge resection (WR) operation among patients with lung adenocarcinoma (ADC) ≤3 cm, by the use of Shanghai Chest Hospital Lung Cancer Database. PATIENTS AND METHODS: There were totally 1938 patients in this study, including 746 WRs and 1192 CLs. The propensity score matching (PSM) was performed to minimize the effect of confounders. Univariable and multivariable cox regressions were analyzed to discover the independent risk factors of recurrence-free survival (RFS) and overall survival (OS)...
June 14, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28615930/prevention-of-influenza-a-h7n9-and-bacterial-infections-in-mice-using-intranasal-immunization-with-live-influenza-vaccine-and-the-group-b-streptococcus-recombinant-polypeptides
#18
Yulia A Desheva, Galina F Leontieva, Tatiana A Kramskaya, Tatiana A Smolonogina, Kornelia B Grabovskaya, Galina O Landgraf, Vadim E Karev, Alexander N Suvorov, Larisa G Rudenko
We investigate the protective effect of combined vaccination based on live attenuated influenza vaccine (LAIV) and group B streptococcus (GBS) recombinant polypeptides against potential pandemic H7N9 influenza infection followed by GBS burden. Mice were intranasally immunized using 107 50% egg infectious dose (EID50) of H7N3 LAIV, the mix of the 4 GBS peptides (group B streptococcus vaccine [GBSV]), or combined LAIV + GBSV vaccine. The LAIV raised serum hemagglutination-inhibition antibodies against H7N9 in higher titers than against H7N3...
2017: Virology: Research and Treatment
https://www.readbyqxmd.com/read/28615624/circulation-of-hadv-41-with-diverse-genome-types-and-recombination-in-acute-gastroenteritis-among-children-in-shanghai
#19
Peng Li, Lang Yang, Jiayin Guo, Wenwei Zou, Xuebin Xu, Xiaoxia Yang, Xinying Du, Shaofu Qiu, Hongbin Song
Human adenovirus F (HAdV-F) is one of the major causative species detected in acute gastroenteritis in children worldwide. HAdV-F is composed of serotypes 40 and 41. Most studies have reported the prevalence of HAdV-41 and focused on its epidemiologic characteristics. In this study, seventeen samples were identified as HAdV-41 out of 273 fecal specimens from children with acute diarrhea in Shanghai. Five isolates were isolated and subjected to whole genome sequencing and analysis to characterize the genetic variation and evolution...
June 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28613083/the-aldh2-gene-rs671-polymorphism-is-not-associated-with-essential-hypertension
#20
Zhan-Ming Li, Chao-Yue Kong, Ke-Yu Sun, Li-Shun Wang
Essential hypertension (EH) is a worldwide problem. Acetaldehyde dehydrogenase 2 (ALDH2) gene has been suggested to be correlated with EH. However, the results are inconsistent. This study aimed to investigate the associations of ALDH2 rs671 polymorphism with EH in a Chinese Han population in Shanghai. Genotype of ALDH2 rs671 was analyzed in 1923 EH patients and 1115 control subjects. We found no association between ALDH2 rs671 and EH risk or EH-related quantitative blood chemistry values. Furthermore, a meta-analysis was performed and the summary results from 11220 patients and 8339 control subjects were consistent with our findings...
June 14, 2017: Clinical and Experimental Hypertension: CHE
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