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Migraine AND Cognition

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https://www.readbyqxmd.com/read/28208851/2d-4d-ratio-and-its-implications-in-medicine
#1
Saravanakumar Jeevanandam, Prathibha K Muthu
Digit ratios, especially 2D:4D ratio, a potential proxy marker for prenatal androgen exposure shows sexual dimorphism. Existing literature and recent research show accumulating evidence on 2D:4D ratio showing correlations with various phenotypic traits in humans. Ratio of 2D:4D is found to correlate negatively to testosterone and positively to oestrogen in the foetus. Interestingly, it is constant since birth and not influenced by the adult hormone levels. Usually, males have lower ratios when compared to females...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28198207/neurophysiological-symptoms-and-aspartame-what-is-the-connection
#2
Arbind Kumar Choudhary, Yeong Yeh Lee
Aspartame (α-aspartyl-l-phenylalanine-o-methyl ester), an artificial sweetener, has been linked to behavioral and cognitive problems. Possible neurophysiological symptoms include learning problems, headache, seizure, migraines, irritable moods, anxiety, depression, and insomnia. The consumption of aspartame, unlike dietary protein, can elevate the levels of phenylalanine and aspartic acid in the brain. These compounds can inhibit the synthesis and release of neurotransmitters, dopamine, norepinephrine, and serotonin, which are known regulators of neurophysiological activity...
February 15, 2017: Nutritional Neuroscience
https://www.readbyqxmd.com/read/28192036/using-acute-performance-on-a-comprehensive-neurocognitive-vestibular-and-ocular-motor-assessment-battery-to-predict-recovery-duration-after-sport-related-concussions
#3
Alicia M Sufrinko, Gregory F Marchetti, Paul E Cohen, R J Elbin, Valentina Re, Anthony P Kontos
BACKGROUND: A sport-related concussion (SRC) is a heterogeneous injury that requires a multifaceted and comprehensive approach for diagnosis and management, including symptom reports, vestibular/ocular motor assessments, and neurocognitive testing. PURPOSE: To determine which acute (eg, within 7 days) vestibular, ocular motor, neurocognitive, and symptom impairments predict the duration of recovery after an SRC. STUDY DESIGN: Cohort study (prognosis); Level of evidence, 2...
February 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28185658/long-term-outcome-in-patients-with-transient-global-amnesia-a-population-based-study
#4
Julieta E Arena, Robert D Brown, Jay Mandrekar, Alejandro A Rabinstein
OBJECTIVE: To study the long-term risk of cerebrovascular events, seizures, and cognitive impairment in patients with transient global amnesia (TGA). PATIENTS AND METHODS: Data for all patients diagnosed with possible TGA in Olmsted County, Minnesota, between January 1, 1985, through December 31, 2010, were retrieved from the Rochester Epidemiology Project database. Transient global amnesia was defined clinically. End points were cerebrovascular event (stroke or transient ischemic attack), seizure, or cognitive impairment (mild cognitive impairment or dementia) during follow-up...
February 6, 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28184165/visual-spatial-training-efficacy-in-children-affected-by-migraine-without-aura-a-multicenter-study
#5
Francesco Precenzano, Maria Ruberto, Lucia Parisi, Margherita Salerno, Agata Maltese, Beatrice Gallai, Rosa Marotta, Serena Marianna Lavano, Francesco Lavano, Michele Roccella
Routinely in the clinical practice, children affected by migraine without aura (MwA) tend to exhibit severe and persistent difficulties within cognitive processes such as attention, memory, and visual-motor integration (VMI) skills. The aim of this study was to assess the visual-spatial and visual-motor abilities among a sample of children with MwA and the effects of a specific computerized training. The study population was composed of 84 patients affected by MwA (39 girls and 45 boys; mean age: 8.91±2.46 years), and they were randomly divided into two groups (group A and group B) comparable for age (P=0...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28167076/brain-network-alterations-in-the-inflammatory-soup-animal-model-of-migraine
#6
Lino Becerra, James Bishop, Gabi Barmettler, Vanessa Kainz, Rami Burstein, David Borsook
Advances in our understanding of the human pain experience have shifted much of the focus of pain research from the periphery to the brain. Current hypotheses suggest that the progression of migraine depends on abnormal functioning of neurons in multiple brain regions. Accordingly, we sought to capture functional brain changes induced by the application of an inflammatory cocktail known as inflammatory soup (IS), to the dura mater across multiple brain networks. Specifically, we aimed to determine whether IS alters additional neural networks indirectly related to the primary nociceptive pathways via the spinal cord to the thalamus and cortex...
February 3, 2017: Brain Research
https://www.readbyqxmd.com/read/28148589/lesson-of-the-month-2-transient-reversible-amnesia-in-multiple-sclerosis
#7
Priya Devi Shanmugarajah, Jane Alty, Oliver Lily, Helen L Ford
Transient amnestic syndromes are fascinating clinical entities and there are several subtypes. Transient global amnesia (TGA) is characterised by sudden onset of anterograde amnesia with repetitive questioning, lasting less than 24 hours. The pathophysiology of TGA involves the medial temporal lobes and hippocampi. Episodes of TGA are thought to involve venous congestion with Valsalva-like activities, vascular or migrainous mechanisms. In contrast, transient epileptic amnesia manifests as brief and frequent episodes of amnesia due to seizure activity in the temporal lobes...
February 2017: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/28125248/development-of-the-cogniphobia-scale-for-headache-disorders-cs-hd-a-pilot-study
#8
Elizabeth K Seng, Jaclyn E Klepper
Cogniphobia refers to the specific fear and avoidance of cognitive exertion, which is believed to precipitate or exacerbate headache. This parallels a well-documented phenomenon, kinesiophobia (fear of movement), in chronic pain. The existing measure of cogniphobia (C-Scale) was developed in persons with posttraumatic headache, and item content may not generalize to the broader headache population. This study aimed to develop and begin the initial examination of the psychometrics of a novel measure of cogniphobia for headache disorders: The Cogniphobia Scale for Headache Disorders (CS-HD)...
January 26, 2017: Psychological Assessment
https://www.readbyqxmd.com/read/28118256/treatment-adherence-in-child-and-adolescent-chronic-migraine-patients-results-from-the-cognitive-behavioral-therapy-and-amitriptyline-trial
#9
Ashley M Kroon Van Diest, Rachelle Ramsey, Susmita Kashikar-Zuck, Shalonda Slater, Kevin Hommel, John W Kroner, Susan LeCates, Marielle A Kabbouche, Hope L O'Brien, Joanne Kacperski, Janelle R Allen, James Peugh, Andrew D Hershey, Scott W Powers
OBJECTIVES: To examine treatment adherence among children and adolescents with chronic migraine who volunteered to be in a clinical trial using three measures: treatment session attendance, therapy homework completion, and preventive medication use via daily diary. METHODS: Analyses are secondary from a trial of 135 youth aged 10 to 17 years diagnosed with chronic migraine and with a Pediatric Migraine Disability score over 20. Participants were randomly assigned to cognitive behavioral therapy plus amitriptyline (CBT+A, N=64) or headache education plus amitriptyline (HE+A, N=71)...
January 21, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28108386/trajectory-of-improvement-in-children-and-adolescents-with-chronic-migraine-results-from-the-cognitive-behavioral-therapy-and-amitriptyline-trial
#10
John W Kroner, James Peugh, Susmita M Kashikar-Zuck, Susan L LeCates, Janelle R Allen, Shalonda K Slater, Marium Zafar, Marielle A Kabbouche, Hope L O'Brien, Chad E Shenk, Ashley M Kroon Van Diest, Andrew D Hershey, Scott W Powers
: We compared headache frequency trajectories between clinical trial participants who received cognitive behavioral therapy plus amitriptyline (CBT+A) or headache education plus amitriptyline (HE+A) to determine if there was differential time course of treatment response between the groups. 135 patients (age 10-17) diagnosed with chronic migraine participated, attending 8 one-hour one-on-one CBT or HE sessions with a trained psychologist for 8 weekly sessions, 2 sessions at weeks 12 and 16, and a post-treatment visit at week 20...
January 17, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28101762/neuropsychological-assessment-in-migraine-patients-a-descriptive-review-on-cognitive-implications
#11
REVIEW
Maria Foti, Viviana Lo Buono, Francesco Corallo, Rosanna Palmeri, Placido Bramanti, Silvia Marino
Migraine is considered a disabling disorder with highly prevalence in population. Recent studies report that migraine patients have a cognitive decline associated to structural brain alterations. We search on PubMed and Web of Science databases and screening references of included studies and review articles for additional citations. From 519 studies identified, only 16 met the inclusion criteria. All studies were conducted on 1479 migraineurs (190 non-migraine headache and 11,978 controls subject) and examined the association between migraine and cognitive impairment...
January 18, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28101484/cadasil-initially-presented-with-a-seizure
#12
Jung-Hwan Oh, Bong Su Kang, Jay Chol Choi
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary disease of the cerebral small blood vessels characterized by recurrent ischemic strokes, migraine, and progressive cognitive impairment. In patients with CADASIL, in whom subcortical white matter structures are typically involved, epileptic seizures have been rarely reported as an initial clinical symptom. We describe a patient genetically confirmed as having CADASIL who initially presented with a seizure...
December 2016: Journal of Epilepsy Research
https://www.readbyqxmd.com/read/28097511/brain-calcification-and-movement-disorders
#13
REVIEW
Vladimir S Kostić, Igor N Petrović
Brain calcifications may be an incidental finding on neuroimaging in normal, particularly older individuals, but can also indicate numerous hereditary and nonhereditary syndromes, and metabolic, environmental, infectious, autoimmune, mitochondrial, traumatic, or toxic disorders. Bilateral calcifications most commonly affecting the basal ganglia may often be found in idiopathic cases, and a new term, primary familial brain calcification (PFBC), has been proposed that recognizes the genetic causes of the disorder and that calcifications occurred well beyond the basal ganglia...
January 2017: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/28071936/concussion-baseline-testing-preexisting-factors-symptoms-and-neurocognitive-performance
#14
Eric Hall, Jordan Cottle, Caroline Ketcham, Kirtida Patel, Kenneth P Barnes
CONTEXT:  Neurocognitive test scores are often considered an important aspect of concussion management. To best use these data, clinicians must understand potential factors that may influence baseline performance on these tests. OBJECTIVE:  To determine preexisting factors that may influence performance on the Immediate Post-Concussion Assessment and Cognitive Test (ImPACT). DESIGN:  Cross-sectional study. SETTING:  Research laboratory...
January 10, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28043031/liver-5-ht7-receptors-a-novel-regulator-target-of-fibrosis-and-inflammation-induced-chronic-liver-injury-in-vivo-and-in-vitro
#15
Beyzagul Polat, Zekai Halici, Elif Cadirci, Emre Karakus, Yasin Bayir, Abdulmecit Albayrak, Deniz Unal
BACKGROUND AND AIM: Hepatocellular cancer (HCC) is the sixth most common cancer and liver fibrosis is strongly associated with HCC. Treatment options are limited, and preventive strategies should be developed. An important step in the beginning of liver fibrosis is a strong inflammatory response. 5-HT7 is the last recognized member of the serotonin receptor family and is expressed in both central nerve system and peripheral system and have a lot of functions like learning, memory, smooth muscular relaxation, in the control of circadian rhythms and thermoregulation, pain and migraine, schizophrenia, anxiety, cognitive disturbances, and even inflammation...
February 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/28028812/a-systematic-review-and-meta-analysis-of-the-efficacy-of-cognitive-behavioral-therapy-for-the-management-of-pediatric-migraine
#16
REVIEW
Qin Xiang Ng, Nandini Venkatanarayanan, Lakshmi Kumar
INTRODUCTION: Migraine headaches are common in children and adolescents. Current pharmacologic treatment options are limited despite the prevalence and debilitating effects of pediatric migraine. Cognitive behavioral therapy (CBT) is an evidence-based practice that focuses on the development of coping strategies and cognitive restructuring to alter the pain experience. Till date, no meta-analysis has been done to examine the use of CBT in pediatric migraine. METHODS: Using the keywords (cognitive behavioral therapy OR cognitive behavior therapy OR cognitive behavioral therapy OR cognitive behavior therapy OR CBT) AND (headache OR migraine), a preliminary search on the PubMed and Ovid database yielded 3841 articles published in English between 1 Jan 1980 and 1 May 2016...
December 28, 2016: Headache
https://www.readbyqxmd.com/read/28028808/structural-gray-matter-alterations-in-chronic-migraine-implications-for-a-progressive-disease
#17
Lars Neeb, Kaili Bastian, Kersten Villringer, Heike Israel, Uwe Reuter, Jochen B Fiebach
OBJECTIVE: To identify possible gray matter alterations in patients with chronic migraine using voxel-based morphometry (VBM). BACKGROUND: VBM studies demonstrate structural alterations of gray matter (GM) in episodic migraine (EM) patients. Some of these alterations correlate with disease duration and headache frequency. We assessed GM alterations in chronic migraine (CM) and EM to evaluate the concept of migraine as a progressive disorder of the brain. METHODS: Individually age and sex-matched subjects with CM or EM (both without aura) and healthy controls (n = 21 per group) underwent magnetic resonance imaging-based VBM...
December 28, 2016: Headache
https://www.readbyqxmd.com/read/28002135/functional-dizziness-from-phobic-postural-vertigo-and-chronic-subjective-dizziness-to-persistent-postural-perceptual-dizziness
#18
Marianne Dieterich, Jeffrey P Staab
PURPOSE OF REVIEW: Functional dizziness is the new term for somatoform or psychogenic dizziness. The aim of this study is to review arguments for the new nomenclature, clinical features, possible pathomechanisms, and comorbidities of functional dizziness. RECENT FINDINGS: The prevalence of functional dizziness as a primary cause of vestibular symptoms amounts to 10% in neuro-otology centers. Rates of psychiatric comorbidity in patients with structural vestibular syndromes are much higher with nearly 50% and with highest rates in patients with vestibular migraine, vestibular paroxysmia, and Ménière's disease...
December 20, 2016: Current Opinion in Neurology
https://www.readbyqxmd.com/read/28002123/functional-dizziness-from-phobic-postural-vertigo-and-chronic-subjective-dizziness-to-persistent-postural-perceptual-dizziness
#19
Marianne Dieterich, Jeffrey P Staab
PURPOSE OF REVIEW: Functional dizziness is the new term for somatoform or psychogenic dizziness. The aim of this study is to review arguments for the new nomenclature, clinical features, possible pathomechanisms, and comorbidities of functional dizziness. RECENT FINDINGS: The prevalence of functional dizziness as a primary cause of vestibular symptoms amounts to 10% in neuro-otology centers. Rates of psychiatric comorbidity in patients with structural vestibular syndromes are much higher with nearly 50% and with highest rates in patients with vestibular migraine, vestibular paroxysmia, and Ménière's disease...
February 2017: Current Opinion in Neurology
https://www.readbyqxmd.com/read/27981543/cognitive-impairment-and-quality-of-life-in-patients-with-migraine-associated-vertigo
#20
N Wang, H-L Huang, H Zhou, C-Y Yu
OBJECTIVE: To study the impact of migraine-associated vertigo (MV) on the cognitive state of patients and their quality of life. PATIENTS AND METHODS: A total of 120 patients were enrolled in the study, including 40 diagnosed with MV, forty with a simple migraine and 40 healthy volunteers. Cognitive assessments were done using the mini-mental state examination (MMSE), and a battery of tests for cognitive functions in performance, memory, language, space and attention during interictal periods...
December 2016: European Review for Medical and Pharmacological Sciences
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