keyword
MENU ▼
Read by QxMD icon Read
search

fibromyalgia clauw

keyword
https://www.readbyqxmd.com/read/29439291/neurobiological-features-of-fibromyalgia-are-also-present-among-rheumatoid-arthritis-patients
#1
Neil Basu, Chelsea M Kaplan, Eric Ichesco, Tony Larkin, Richard E Harris, Alison Murray, Gordon Waiter, Daniel J Clauw
OBJECTIVES: Many rheumatoid arthritis (RA) patients report pain despite excellent control of inflammation with immunotherapies. Variable degrees of co-existing fibromyalgia (FM) may explain this disparity. FM has been characterised by aberrant brain functional connectivity, especially between the Default Mode Network (DMN) and insula. We hypothesised that RA patients reporting the highest 2011 ACR FM survey criteria scores- a continuous measure of FM degree also known as fibromyalgianess (FMness)- would demonstrate functional connectivity abnormalities similar to FM...
February 13, 2018: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29392206/reduced-intraepidermal-nerve-fiber-density-after-a-sustained-increase-in-insular-glutamate-a-proof-of-concept-study-examining-the-pathogenesis-of-small-fiber-pathology-in-fibromyalgia
#2
Steven E Harte, Daniel J Clauw, John M Hayes, Eva L Feldman, Irene C St Charles, Christopher J Watson
Introduction: Neuroimaging reveals increased glutamate within the insula of patients with fibromyalgia (FM), suggesting a link between FM symptoms and increased central excitatory neurotransmission. Many patients with FM also present with decreased intraepidermal nerve fiber density (IENFD), consistent with small fiber pathology. It remains unknown, however, whether either of these mechanistic findings represent a cause or a consequence of the other. This study tests the hypothesis that an excitatory imbalance within the insula leads to small fiber pathology...
May 2017: Pain Reports (Baltimore, Md.)
https://www.readbyqxmd.com/read/29360608/resting-functional-connectivity-of-the-periaqueductal-gray-is-associated-with-normal-inhibition-and-pathological-facilitation-in-conditioned-pain-modulation
#3
Daniel E Harper, Eric Ichesco, Andrew Schrepf, Johnson P Hampson, Daniel J Clauw, Tobias Schmidt-Wilcke, Richard E Harris, Steven E Harte
Conditioned pain modulation (CPM), a psychophysical paradigm that is commonly used to infer the integrity of endogenous pain-altering systems by observation of the effect of one noxious stimulus on another, has previously identified deficient endogenous analgesia in fibromyalgia (FM) and other chronic pain conditions. The mechanisms underlying this deficiency, be they insufficient inhibition and/or active facilitation, are largely unknown. The present cross sectional study used a combination of behavioral CPM testing, voxel based morphometry (VBM), and resting state functional connectivity to identify neural correlates of CPM in healthy controls (HC; n=14) and FM patients (n=15), and to probe for differences that could explain the pain-facilitative CPM that was observed in our patient sample...
January 19, 2018: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29321621/functional-brain-network-mechanism-of-hypersensitivity-in-chronic-pain
#4
UnCheol Lee, Minkyung Kim, KyoungEun Lee, Chelsea M Kaplan, Daniel J Clauw, Seunghwan Kim, George A Mashour, Richard E Harris
Fibromyalgia (FM) is a chronic widespread pain condition characterized by augmented multi-modal sensory sensitivity. Although the mechanisms underlying this sensitivity are thought to involve an imbalance in excitatory and inhibitory activity throughout the brain, the underlying neural network properties associated with hypersensitivity to pain stimuli are largely unknown. In network science, explosive synchronization (ES) was introduced as a mechanism of hypersensitivity in diverse biological and physical systems that display explosive and global propagations with small perturbations...
January 10, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29112660/opioid-prescribing-patterns-patient-use-and-postoperative-pain-after-hysterectomy-for-benign-indications
#5
Sawsan As-Sanie, Sara R Till, Erika L Mowers, Courtney S Lim, Bethany D Skinner, Laura Fritsch, Alex Tsodikov, Vanessa K Dalton, Daniel J Clauw, Chad M Brummett
OBJECTIVE: To quantify physician prescribing patterns and patient opioid use in the 2 weeks after hysterectomy at an academic institution and to determine whether patient factors predict postsurgical opioid use and pain recovery. METHODS: We conducted a prospective quality initiative study by recruiting all English-speaking patients undergoing hysterectomy for benign, nonobstetric indications at a university hospital between August 2015 and December 2015, excluding those with major medical morbidities or substance abuse...
December 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28967359/the-role-of-centralised-pain-in-osteoarthritis
#6
REVIEW
Daniel J Clauw, Afton L Hassett
The mechanisms underlying chronic pain states, including osteoarthritis, differ from those underlying acute pain. In chronic pain states, central nervous system (CNS) factors often play a particularly prominent role. In many individuals with chronic pain, pain can occur with minimal or no evidence of ongoing nociceptive input. Medical subspecialties have applied a wide-range of labels to these pain conditions including fibromyalgia, irritable bowel syndrome and interstitial cystitis to name just a few. These same CNS processes can augment or magnify pain when there is ongoing nociceptive input, as in conditions such as osteoarthritis or autoimmune disorders...
September 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28943233/unravelling-fibromyalgia-steps-toward-individualized-management
#7
Winfried Häuser, Serge Perrot, Daniel J Clauw, Mary-Ann Fitzcharles
The heterogeneity of the clinical presentation and the pathophysiologic mechanisms associated with fibromyalgia (FM), and the modest results on average for any therapy, call for a more individualized management strategy. Individualized treatment can be on the basis of subgrouping of patients according to associated conditions (mental health problems, chronic overlapping pain conditions, other somatic diseases) or on disease severity. Categorizing FM as mild, moderate, or severe can be on the basis of clinical assessment (eg, degree of daily functioning) or on questionnaires...
September 21, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28814895/caffeine-as-an-opioid-analgesic-adjuvant-in-fibromyalgia
#8
J Ryan Scott, Afton L Hassett, Chad M Brummett, Richard E Harris, Daniel J Clauw, Steven E Harte
BACKGROUND: Caffeine's properties as an analgesic adjuvant with nonsteroidal anti-inflammatory drugs/acetaminophen are well documented. However, little clinical research has explored caffeine's effects on opioid analgesia. This study assessed the effects of caffeine consumption on pain and other symptoms in opioid-using and nonusing chronic pain patients meeting the survey criteria for fibromyalgia. MATERIALS AND METHODS: Patients presenting to a university-based pain clinic completed validated self-report questionnaires assessing symptoms...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28796118/emotional-awareness-and-expression-therapy-cognitive-behavioral-therapy-and-education-for-fibromyalgia-a-cluster-randomized-controlled-trial
#9
Mark A Lumley, Howard Schubiner, Nancy A Lockhart, Kelley M Kidwell, Steven E Harte, Daniel J Clauw, David A Williams
Patients with fibromyalgia (FM) experience increased lifetime levels of psychosocial adversity, trauma, and emotional conflict. To address these risk factors, we developed emotion awareness and expression therapy (EAET) and tested its benefits against an active control condition, FM education, and the field's gold standard intervention for FM, cognitive behavioral therapy (CBT) for symptom management. Adults with FM (N = 230) formed 40 treatment groups, which were randomized to EAET, CBT, or education and given 8, 90-minute sessions...
December 2017: Pain
https://www.readbyqxmd.com/read/28692006/brain-signature-and-functional-impact-of-centralized-pain-a-multidisciplinary-approach-to-the-study-of-chronic-pelvic-pain-mapp-network-study
#10
Jason J Kutch, Eric Ichesco, Johnson P Hampson, Jennifer S Labus, Melissa A Farmer, Katherine T Martucci, Timothy J Ness, Georg Deutsch, A Vania Apkarian, Sean C Mackey, David J Klumpp, Anthony J Schaeffer, Larissa V Rodriguez, Karl J Kreder, Dedra Buchwald, Gerald L Andriole, H Henry Lai, Chris Mullins, John W Kusek, J Richard Landis, Emeran A Mayer, J Quentin Clemens, Daniel J Clauw, Richard E Harris
Chronic pain is often measured with a severity score that overlooks its spatial distribution across the body. This widespread pain is believed to be a marker of centralization, a central nervous system process that decouples pain perception from nociceptive input. Here, we investigated whether centralization is manifested at the level of the brain using data from 1079 participants in the Multidisciplinary Approach to the Study of Chronic Pelvic Pain Research Network (MAPP) study. Participants with a clinical diagnosis of urological chronic pelvic pain syndrome (UCPPS) were compared to pain-free controls and patients with fibromyalgia, the prototypical centralized pain disorder...
June 30, 2017: Pain
https://www.readbyqxmd.com/read/28562155/challenges-of-implementing-fibromyalgia-treatment-guidelines-in-current-clinical-practice
#11
REVIEW
Lesley M Arnold, Daniel J Clauw
The current diagnostic and treatment pathway for patients with fibromyalgia (FM) is lengthy, complex, and characterized by multiple physician visits with an average 2-year wait until diagnosis. It is clear that effective identification and appropriate treatment of FM remain a challenge in current clinical practice. Ideally, FM management involves a multidisciplinary approach with the preferable patient pathway originating in primary care but supported by a range of health care providers, including referral to specialist care when necessary...
September 2017: Postgraduate Medicine
https://www.readbyqxmd.com/read/28319509/a-high-preoperative-pain-and-symptom-profile-predicts-worse-pain-outcomes-for-children-after-spine-fusion-surgery
#12
Terri Voepel-Lewis, Michelle S Caird, Alan R Tait, Shobha Malviya, Frances A Farley, Ying Li, Matthew D Abbott, Tara van Veen, Afton L Hassett, Daniel J Clauw
BACKGROUND: Preoperative pain predicts persistent pain after spine fusion, yet little is understood about the nature of that pain, related symptoms, and how these symptoms relate to postoperative pain outcomes. This prospective study examined children's baseline pain and symptom profiles and the association between a high symptom profile and postoperative outcomes. METHODS: Seventy children (aged 10-17 years) scheduled for correction of idiopathic scoliosis completed pain and symptom surveys during their preoperative visit (ie, pain intensity [0-10 numeric rating scores], a pediatric version of the 2011 fibromyalgia survey criteria [including pain locations and symptom severity scale], neuropathic pain symptoms [painDETECT], and Patient-Reported Outcome Measurement System measures of fatigue, depression, function, pain interference, and pain catastrophizing)...
May 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28182834/impact-of-moving-from-a-widespread-to-multisite-pain-definition-on-other-fibromyalgia-symptoms
#13
Linda E Dean, Lesley Arnold, Leslie Crofford, Robert Bennett, Don Goldenberg, Mary-Ann Fitzcharles, Eduardo S Paiva, Roland Staud, Dan Clauw, Piercarlo Sarzi-Puttini, Gareth T Jones, Abimbola Ayorinde, Elisa Flüß, Marcus Beasley, Gary J Macfarlane
OBJECTIVE: To investigate whether associations between pain and the additional symptoms associated with fibromyalgia are different in persons with chronic widespread pain (CWP) compared to multisite pain (MSP), with or without joint areas. METHODS: Six studies were used: 1958 British birth cohort, Epidemiology of Functional Disorders, Kid Low Back Pain, Managing Unexplained Symptoms (Chronic Widespread Pain) in Primary Care: Involving Traditional and Accessible New Approaches, Study of Health and its Management, and Women's Health Study (WHEST; females)...
February 9, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28162746/-495-emotional-abilities-moderate-responses-to-different-psychological-interventions-for-fibromyalgia
#14
H Doherty, N Lockhart, M Lumley, D Williams, H Schubiner, D Clauw
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28162316/-509-the-past-fm-pain-and-stress-treatment-for-fibromyalgia-randomized-controlled-trial-main-effects-of-emotional-awareness-and-expression-and-cognitive-behavioral-therapies
#15
M Lumley, H Schubiner, D Clauw, N Lockhart, K Kidwell, D Williams
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28050051/discordant-dry-eye-disease-an-american-ophthalmological-society-thesis
#16
Roni M Shtein, Daniel E Harper, Vincent Pallazola, Steven E Harte, Munira Hussain, Alan Sugar, David A Williams, Daniel J Clauw
PURPOSE: To improve understanding of dry eye disease and highlight a subgroup of patients who have a component of central sensitization and neuropathic pain contributing to their condition. METHODS: Prospective, cross-sectional, IRB-approved study comparing isolated dry eye disease (n=48) to fibromyalgia (positive control; n=23) and healthy (negative control; n=26) individuals with ocular surface examination, corneal confocal microscopy, quantitative sensory testing, and self-reported ocular symptoms and systemic associations...
August 2016: Transactions of the American Ophthalmological Society
https://www.readbyqxmd.com/read/27916278/2016-revisions-to-the-2010-2011-fibromyalgia-diagnostic-criteria
#17
Frederick Wolfe, Daniel J Clauw, Mary-Ann Fitzcharles, Don L Goldenberg, Winfried Häuser, Robert L Katz, Philip J Mease, Anthony S Russell, Irwin Jon Russell, Brian Walitt
OBJECTIVES: The provisional criteria of the American College of Rheumatology (ACR) 2010 and the 2011 self-report modification for survey and clinical research are widely used for fibromyalgia diagnosis. To determine the validity, usefulness, potential problems, and modifications required for the criteria, we assessed multiple research reports published in 2010-2016 in order to provide a 2016 update to the criteria. METHODS: We reviewed 14 validation studies that compared 2010/2011 criteria with ACR 1990 classification and clinical criteria, as well as epidemiology, clinical, and databank studies that addressed important criteria-level variables...
December 2016: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/27713648/a-novel-paradigm-to-evaluate-conditioned-pain-modulation-in-fibromyalgia
#18
Cynthia J Schoen, Jacob N Ablin, Eric Ichesco, Rupal J Bhavsar, Laura Kochlefl, Richard E Harris, Daniel J Clauw, Richard H Gracely, Steven E Harte
INTRODUCTION: Application of noxious stimulation to one body area reduces pain sensitivity in a remote body area through activation of an endogenous pain-inhibitory network, a behavioral phenomenon referred to as conditioned pain modulation (CPM). The efficiency of CPM is predictive of a variety of health outcomes, while impaired CPM has been associated with various chronic pain conditions. Current methods used to assess CPM vary widely, and interest in CPM method development remains strong...
2016: Journal of Pain Research
https://www.readbyqxmd.com/read/27641311/the-association-between-a-history-of-lifetime-traumatic-events-and-pain-severity-physical-function-and-affective-distress-in-patients-with-chronic-pain
#19
Andrea L Nicol, Christine B Sieberg, Daniel J Clauw, Afton L Hassett, Stephanie E Moser, Chad M Brummett
Evidence suggests that pain patients who report lifetime abuse experience greater psychological distress, have more severe pain and other physical symptoms, and greater functional disability. The aim of the present study was to determine the associations between a history of lifetime abuse and affective distress, fibromyalgianess (measured using the 2011 Fibromyalgia Survey), pain severity and interference, and physical functioning. A cross-sectional analysis of 3,081 individuals presenting with chronic pain was performed using validated measures and a history of abuse was assessed via patient self-report...
December 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/27420606/endogenous-opioidergic-dysregulation-of-pain-in-fibromyalgia-a-pet-and-fmri-study
#20
Andrew Schrepf, Daniel E Harper, Steven E Harte, Heng Wang, Eric Ichesco, Johnson P Hampson, Jon-Kar Zubieta, Daniel J Clauw, Richard E Harris
Endogenous opioid system dysfunction potentially contributes to chronic pain in fibromyalgia (FM), but it is unknown if this dysfunction is related to established neurobiological markers of hyperalgesia. We previously reported that µ-opioid receptor (MOR) availability was reduced in patients with FM as compared with healthy controls in several pain-processing brain regions. In the present study, we compared pain-evoked functional magnetic resonance imaging with endogenous MOR binding and clinical pain ratings in female opioid-naive patients with FM (n = 18) using whole-brain analyses and regions of interest from our previous research...
October 2016: Pain
keyword
keyword
107059
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"