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Evoked potential and anesthesia

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https://www.readbyqxmd.com/read/28104012/-simultaneous-triple-semicircular-canal-plugging-and-cochlear-implantation-in-advanced-meniere-s-disease
#1
D G Zhang, L Xu, Y C Han, Y F Lyu, J F Luo, Y W Li, R J Wang, Z M Fan, H B Wang
Objective: To evaluate the feasibility of combining simultaneous triple semicircular canal plugging (TSCP) and cochlear implantation (CI) to treat vertigo and hearing loss in advanced Meniere's disease(MD) patients, so as to provide an alternative surgical procedure for treating this disorder. Methods: Data from seven patients, who were referred to our hospital and diagnosed with unilateral MD strictly meeting the criteria issued by Chinese Academy of Otolaryngology-Head and Neck Surgery Committee (2006), from Jan...
January 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28062278/%C3%AE-lipoic-acid-ameliorates-oral-mucositis-and-oxidative-stress-induced-by-methotrexate-in-rats-histological-and-immunohistochemical-study
#2
Amal A M Ahmed, Manar A A Selim, Norhan M El-Sayed
AIM: Oral mucositis is a common adverse effect of Methotrexate (MTX) that may limit its clinical use. Oxidative stress and apoptosis have been proposed to mediate MTX toxicity. The current study was conducted to assess the conceivable protective effect of α-lipoic acid (LA) against MTX induced toxicity on both buccal and lingual mucosae. MAIN METHODS: Thirty male Wistar rats were allocatedinto three groups; control, MTX-treated group subjected to single intraperitoneal injection of MTX (20mg/kg, i...
January 3, 2017: Life Sciences
https://www.readbyqxmd.com/read/28045856/a-multiparametric-alarm-criterion-for-motor-evoked-potential-monitoring-during-spine-deformity-surgery
#3
Martín J Segura, María E Talarico, Mariano A Noel
PURPOSE: This is a pilot study to compare changes in the amplitude, area below the curve, number of phases, duration, and latency of the intraoperative transcranial motor evoked potentials (TcMEP) for early detection of impending spinal cord injury. An empirical ratio calculated by a combination of the above-mentioned parameters was also assessed. METHODS: Intraoperative TcMEP recordings from five patients presenting with neuromuscular kyphoscoliosis, idiopathic scoliosis, achondroplasia and lumbar kyphosis, congenital kyphosis, and achondroplasia with cervical instability were reviewed...
January 2017: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/28017534/direct-motor-evoked-potentials-and-cortical-mapping-using-the-nim%C3%A2-nerve-monitoring-system-a-technical-note
#4
Suparna Bharadwaj, Faizal Haji, Matthew Hebb, Jason Chui
Motor evoked potentials (MEPs) are commonly used to prevent neurological injury when operating in close proximity to the motor cortex or corticospinal pathway. We report a novel application of the NIM® nerve monitoring system (Medtronic@ NIM response 3.0) for intraoperative direct cortical (dc)-MEPs monitoring. A 69-year-old female patient presented with a 4month history of progressive left hemiparesis resulting from a large right sided posterior frontal meningioma that abutted and compressed the motor cortex...
December 22, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28010998/comparison-of-multimodal-intraoperative-neurophysiological-monitoring-efficacy-in-early-childhood-and-school-aged-children-undergoing-spinal-surgery
#5
Alpaslan Şenköylü, Murat Zinnuroğlu, Alp Börçek, Erdem Aktaş, İrfan Güngör, Mehmet Beyazova
OBJECTIVE: The aim of this study was to compare the performance of multimodal intraoperative neurophysiological monitoring (MIONM) in children below and over 6 years of age. METHODS: 43 children, diagnosed with spinal pathologies were divided into two cohorts according to their age and enrolled in the study. Those under the age of 6 consisted group A, whereas those between the age of 6 and 11 consisted group B. All patients underwent spinal surgical procedures according to their diagnosis...
December 20, 2016: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/27938608/-detection-of-the-electric-brain-stem-auditory-response-before-cochlear-implantation-and-its-significance
#6
B Wang, K L Cao, C G Wei, Y Wang, H Li
Objective: Analysis of the outcome of the electric brain stem auditory response (EABR) before cochlear implantation (CI) and the mapping parameters after CI in 187 cases, to explore the significance of EABR before CI. Methods: From February, 2008 to December, 2014, EABR were performed in 187 patients with normal cochlear structures before CI with Nucleus 24R multi-channel cochlear. Including 105 cases of male, 82 cases of female; 152 cases of no residual hearing, 35 cases of residual hearing. Self-design electrical stimulator and US Bio-logic auditory evoked potential were taken, EABR were performed under general anesthesia before CI, recording EABR waveforms, measuring the latency of Ⅱ, Ⅲ, Ⅳ, Ⅴ wave and the Ⅲ-Ⅴ interval, Ⅴ-wave amplitude, Ⅴ-wave threshold and I/O curve slope...
November 7, 2016: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/27896270/the-assessment-of-facial-expressions-in-piglets-undergoing-tail-docking-and-castration-toward-the-development-of-the-piglet-grimace-scale
#7
Pierpaolo Di Giminiani, Victoria L M H Brierley, Annalisa Scollo, Flaviana Gottardo, Emma M Malcolm, Sandra A Edwards, Matthew C Leach
Many piglets are exposed to potentially painful husbandry procedures within the first week of life, including tail docking and castration, without the provision of either anesthesia or analgesia. The assessment methods used to evaluate pain experienced by piglets are often affected by low specificity and practical limitations, prompting the investigation of alternative methodologies. The assessment of changes in facial expression following a painful event has been successfully applied to several species. The objective of this pilot study was to evaluate the utility of a Grimace Scale applied to neonatal pigs to evaluate pain evoked by tail docking and castration...
2016: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/27851693/the-correlation-between-recordable-meps-and-motor-function-during-spinal-surgery-for-resection-of-thoracic-spinal-cord-tumor
#8
LanJun Guo, Yan Li, Ruquan Han, Adrian W Gelb
BACKGROUND: Motor evoked potentials (MEPs) are commonly used during surgery for spinal cord tumor resection. However, it can be difficult to record reliable MEPs from the muscles of the lower extremities during surgery in patients with preoperative weakness due to spinal cord compression. In this study, motor function of patients' lower extremities and their association with intraoperative MEP recording were compared. PATIENTS AND METHODS: Patients undergoing thoracic spinal cord tumor resection were studied...
November 15, 2016: Journal of Neurosurgical Anesthesiology
https://www.readbyqxmd.com/read/27766073/differences-in-motor-evoked-potentials-induced-in-rats-by-transcranial-magnetic-stimulation-under-two-separate-anesthetics-implications-for-plasticity-studies
#9
Matthew Sykes, Natalie A Matheson, Philip W Brownjohn, Alexander D Tang, Jennifer Rodger, Jonathan B H Shemmell, John N J Reynolds
Repetitive transcranial magnetic stimulation (rTMS) is primarily used in humans to change the state of corticospinal excitability. To assess the efficacy of different rTMS stimulation protocols, motor evoked potentials (MEPs) are used as a readout due to their non-invasive nature. Stimulation of the motor cortex produces a response in a targeted muscle, and the amplitude of this twitch provides an indirect measure of the current state of the cortex. When applied to the motor cortex, rTMS can alter MEP amplitude, however, results are variable between participants and across studies...
2016: Frontiers in Neural Circuits
https://www.readbyqxmd.com/read/27739939/intraoperative-auditory-steady-state-monitoring-during-surgery-in-the-cerebellopontine-angle-for-estimation-of-postoperative-hearing-classes
#10
Stefan Rampp, Leonhard Rensch, Sebastian Simmermacher, Torsten Rahne, Christian Strauss, Julian Prell
OBJECTIVE Brainstem auditory evoked potentials (BAEPs) have been used for intraoperative monitoring of the auditory nerve for many years. However, BAEPs yield limited information about the expected postoperative hearing quality and speech perception. The auditory steady-state response (ASSR) enables objective audiograms to be obtained in patients under anesthesia. These ASSRs could be used for intraoperative estimation of hearing classes to improve the postoperative outcome and quality of life. Studies investigating the clinical use of ASSRs during total intravenous anesthesia are currently lacking...
October 14, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27689422/intraoperative-electrophysiological-monitoring-for-c1-2-spinal-cord-stimulation
#11
Laura M Muncie, Nathaniel R Ellens, Emeline Tolod-Kemp, Claudio A Feler, John S Winestone
OBJECTIVE This study is a retrospective case series involving C1-2 spinal cord stimulation in patients with complex regional pain syndrome (CRPS) under general endotracheal anesthesia. Currently, C1-2 paddle lead placement is an accepted practice, which provides effective cervical stimulation to ameliorate upper-extremity and sometimes lower-extremity symptoms experienced by patients with CRPS. However, this technique must be performed under general endotracheal anesthesia rather than in an awake or semiconscious state due to intraoperative safety concerns and patient comfort...
September 30, 2016: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/27612851/systematic-review-of-motor-evoked-potentials-monitoring-during-thoracic-and-thoracoabdominal-aortic-aneurysm-open-repair-surgery-a-diagnostic-meta-analysis
#12
REVIEW
Yuu Tanaka, Masahiko Kawaguchi, Yoshinori Noguchi, Kenji Yoshitani, Mikito Kawamata, Kenichi Masui, Takeo Nakayama, Yoshitugu Yamada
Motor evoked potential (MEP) monitoring has been used to prevent neurological complications such as paraplegia in patients who underwent thoracic or thoracoabdominal aortic aneurysm (TAA/TAAA) surgery. The object of this study was making a systematic review to survey the performance of MEP monitoring during TAA/TAAA open repair surgery. We searched electronic databases for relevant studies. We summarized the diagnostic data with summary sensitivity, summary specificity and forest plots of pooled sensitivity, and conducted sub-group analysis...
December 2016: Journal of Anesthesia
https://www.readbyqxmd.com/read/27567759/after-effects-of-anodal-transcranial-direct-current-stimulation-on-the-excitability-of%C3%A2-the%C3%A2-motor-cortex-in-rats
#13
Ho Koo, Min Sun Kim, Sang Who Han, Walter Paulus, Michael A Nitche, Yun-Hee Kim, Hyoung-Ihl Kim, Sung-Hwa Ko, Yong-Il Shin
PURPOSE: Transcranial direct current stimulation (tDCS) is increasingly seen as a useful tool for noninvasive cortical neuromodulation. A number of studies in humans have shown that when tDCS is applied to the motor cortex it can modulate cortical excitability. It is especially interesting to note that when applied with sufficient duration and intensity, tDCS can enable long-lasting neuroplastic effects. However, the mechanism by which tDCS exerts its effects on the cortex is not fully understood...
September 21, 2016: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/27559984/comparison-of-false-negative-positive-results-of-intraoperative-evoked-potential-monitoring-between-no-and-partial-neuromuscular-blockade-in-patients-receiving-propofol-remifentanil-based-anesthesia-during-cerebral-aneurysm-clipping-surgery-a-retrospective
#14
Sung-Hoon Kim, Seok-Joon Jin, Myong-Hwan Karm, Young-Jin Moon, Hye-Won Jeong, Jae-Won Kim, Seung-Il Ha, Joung-Uk Kim
Although the elicited responses of motor evoked potential (MEP) monitoring are very sensitive to suppression by anesthetic agents and muscle relaxants, the use of neuromuscular blockade (NMB) during MEP monitoring is still controversial because of serious safety concerns and diagnostic accuracy. Here, we evaluated the incidence of unacceptable movement and compared false-negative MEP results between no and partial NMB during cerebral aneurysm clipping surgery. We reviewed patient medical records for demographic data, anesthesia regimen, neurophysiology event logs, MEP results, and clinical outcomes...
August 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27555126/recovery-of-laryngeal-nerve-function-with-sugammadex-after-rocuronium-induced-profound-neuromuscular-block
#15
Vittorio Pavoni, Lara Gianesello, Cristiana Martinelli, Andrew Horton, Alessandra Nella, Gabriele Gori, Martina Simonelli, Giuseppe De Scisciolo
STUDY OBJECTIVE: The aim of this study was to evaluate the efficacy of sugammadex in reversing profound rocuronium-induced neuromuscular block at the laryngeal adductor muscles using motor-evoked potentials (mMEPs). DESIGN: A prospective observational study. SETTING: University surgical center. PATIENTS: Twenty patients with American Society of Anesthesiologists physical class I-II status who underwent propofol-remifentanil anesthesia for the surgery of the thyroid gland...
September 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27517084/local-versus-global-effects-of-isoflurane-anesthesia-on-visual-processing-in-the-fly-brain
#16
Dror Cohen, Oressia H Zalucki, Bruno van Swinderen, Naotsugu Tsuchiya
What characteristics of neural activity distinguish the awake and anesthetized brain? Drugs such as isoflurane abolish behavioral responsiveness in all animals, implying evolutionarily conserved mechanisms. However, it is unclear whether this conservation is reflected at the level of neural activity. Studies in humans have shown that anesthesia is characterized by spatially distinct spectral and coherence signatures that have also been implicated in the global impairment of cortical communication. We questioned whether anesthesia has similar effects on global and local neural processing in one of the smallest brains, that of the fruit fly (Drosophila melanogaster)...
July 2016: ENeuro
https://www.readbyqxmd.com/read/27484701/effects-of-dexmedetomidine-on-motor-and-somatosensory-evoked-potentials-in-patients-with-thoracic-spinal-cord-tumor-a-randomized-controlled-trial
#17
Yan Li, Lingzhong Meng, Yuming Peng, Hui Qiao, Lanjun Guo, Ruquan Han, Adrian W Gelb
BACKGROUND: We hypothesized that the addition of dexmedetomidine in a clinically relevant dose to propofol-remifentanil anesthesia regimen does not exert an adverse effect on motor-evoked potentials (MEP) and somatosensory-evoked potentials (SSEP) in adult patients undergoing thoracic spinal cord tumor resection. METHODS: Seventy-one adult patients were randomized into three groups. Propofol group (n = 25): propofol-remifentanil regimenand the dosage was adjusted to maintain the bispectral index (BIS) between 40 and 50...
August 2, 2016: BMC Anesthesiology
https://www.readbyqxmd.com/read/27468970/neuroprotective-effect-of-propofol-against-excitotoxic-injury-to-locomotor-networks-of-the-rat-spinal-cord-in%C3%A2-vitro
#18
Jaspreet Kaur, Javier Flores Gutiérrez, Andrea Nistri
Although neuroprotection to contain the initial damage of spinal cord injury (SCI) is difficult, multicentre studies show that early neurosurgery under general anaesthesia confers positive benefits. An interesting hypothesis is that the general anaesthetic itself might largely contribute to neuroprotection, although in vivo clinical settings hamper studying this possibility directly. To further test neuroprotective effects of a widely used general anaesthetic, we studied if propofol could change the outcome of a rat isolated spinal cord SCI model involving excitotoxicity evoked by 1 h application of kainate with delayed consequences on neurons and locomotor network activity...
October 2016: European Journal of Neuroscience
https://www.readbyqxmd.com/read/27468733/a-novel-mouthpiece-prevents-bite-injuries-caused-by-intraoperative-transcranial-electric-motor-evoked-potential-monitoring
#19
Kyoko Oshita, Noboru Saeki, Takayasu Kubo, Hitoshi Abekura, Nobuhiro Tanaka, Masashi Kawamoto
PURPOSE: Intraoperative transcranial motor-evoked potential monitoring causes contraction of the masseter muscles, which may cause injuries to the oral cavity and damage to the orotracheal tube. We developed a mouthpiece made from vinyl-silicone impression material to prevent these injuries. The purpose of this study was to examine its efficacy and safety. METHODS: Twenty-two patients undergoing spinal surgery under transcranial motor-evoked potential monitoring were fitted with bespoke vinyl-silicone mouthpieces by dentists before surgery...
October 2016: Journal of Anesthesia
https://www.readbyqxmd.com/read/27453092/how-to-perform-abr-in-young-children
#20
I Rouillon, M Parodi, F Denoyelle, N Loundon
The diagnosis of hearing loss, especially in the context of newborn hearing screening, is mostly based on auditory brainstem response (ABR). According to the official CCAM nomenclature, ABR consists of recording early auditory evoked potentials to detect thresholds, study conduction times and measure amplitudes (corresponding to codes CDQP006 when performed without general anesthesia, and CDQP014 when performed with general anesthesia). ABR must be rigorously performed and interpreted, always in combination with a complete ENT examination and behavioral audiometry as soon as possible...
December 2016: European Annals of Otorhinolaryngology, Head and Neck Diseases
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