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ceftriaxone in diarrhea for escherichia coli

Roholla Taghadosi, Mohammad Reza Shakibaie, Reza Ghanbarpour, Hossein Hosseini-Nave
Background and Objectives: The objectives of this study were to evaluate the antibiotic resistance profiles, biofilm formation, presence of antigen 43 ( Ag 43) gene, and transfer of antibiotic resistance phenotype among non-O157 Shiga toxin producing Escherichia coli (STEC). Materials and Methods: From October 2014 to November 2015 a total of 276 stool samples were collected from healthy calves, goats and 395 patients with the sign of nonbloody diarrhea and screened for presence of stx and serotype O157 genes by polymerase chain reaction (PCR) technique...
April 2017: Iranian Journal of Microbiology
Abhishek Mandal, Abhishek Sengupta, Ajay Kumar, Utpal K Singh, Anil K Jaiswal, Pradeep Das, Sushmita Das
Background: Childhood diarrheal diseases remain highly endemic in India, but the emergence of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli among children with diarrhea in Bihar remains elusive. In this study, we determine and characterize ESBL-producing E coli pathotypes among hospitalized diarrheal preschool children living in low socioeconomic level communities in Bihar, India. Materials and methods: The stool samples were collected everyday throughout the year for 2 consecutive years...
2017: Infectious Diseases
Maneli Aminshahidi, Amir Arastehfar, Gholamreza Pouladfar, Esmayil Arman, Fereshteh Fani
This study was conducted to find the etiology of acute diarrhea in Iranian children and determine the antimicrobial resistance patterns. The pathogenic bacteria were recovered from 110/269 (40.9%) diarrheal fecal samples with the following profiles: the most predominant pathogen was diarrheagenic Escherichia coli (DEC) (43.6%), comprising enteroaggregative E. coli (23.6%), enteropathogenic E. coli (10.9%), enteroinvasive E. coli (5.5%), and enterotoxigenic E. coli (3.6%); Shigella spp. (37.3%), Salmonella spp...
December 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
Rebecca L Brander, Judd L Walson, Grace C John-Stewart, Jacqueline M Naulikha, Janet Ndonye, Nancy Kipkemoi, Doreen Rwigi, Benson O Singa, Patricia B Pavlinac
BACKGROUND: Reduced antimicrobial susceptibility threatens treatment efficacy in sub-Saharan Africa, where data on the burden and correlates of antibiotic resistance among enteric pathogens are limited. METHODS: Fecal samples from children aged 6 mos-15 yrs presenting with acute diarrhea in western Kenya were cultured for bacterial pathogens. HIV-uninfected children with identified Shigella or Salmonella species or pathogenic Escherichia coli (EPEC, ETEC, EAEC or EIEC) were included in this cross-sectional sub-study...
October 2017: PLoS Neglected Tropical Diseases
Hailing Chang, Ling Zhang, Yanling Ge, Jiehao Cai, Xiangshi Wang, Zheng Huang, Jiayin Guo, Hao Xu, Zhen Gu, Hong Chen, Xuebin Xu, Mei Zeng
BACKGROUND: Prevention and control of childhood diarrhea is a global priority. We conducted a case-control study of childhood diarrhea in Shanghai. METHODS: We prospectively recruited diarrheal children in an outpatient setting. Nondiarrheal controls were individually matched to cases. Rotavirus, norovirus and bacterial pathogens were examined. Clinical and epidemiologic data were obtained at enrollment and follow-up. RESULTS: Potential pathogens identified in 680 diarrheal cases and 680 controls were rotavirus (19...
November 2017: Pediatric Infectious Disease Journal
Xu-Hui Zhu, Lei Tian, Zhong-Ju Cheng, Wei-Yong Liu, Song Li, Wei-Ting Yu, Wen-Qian Zhang, Xu Xiang, Zi-Yong Sun
BACKGROUND: Acute diarrhea remains the serious problem in developing countries, especially among children under 5 years of age. Currently, only two or three common diarrhea pathogens were screened at most hospitals in China. The aim of this study was to provide a wide variety of diarrhea pathogens and their antimicrobial resistance patterns in children under 5 years of age. METHODS: Totally 381 stool samples collected from Tongji Hospital between July 1, 2014 and June 30, 2015 were tested by culture and/or polymerase chain reaction for eight kinds of bacteria and five kinds of viruses...
August 20, 2016: Chinese Medical Journal
Banafshe Dormanesh, Soheila Siroosbakhat, Peyman Karimi Goudarzi, Ladan Afsharkhas
BACKGROUND: Shiga-toxigenic Escherichia coli is an important human pathogen cause of diarrhea, hemorrhagic colitis, hemolytic uremic syndrome and thrombotic thrombocytopenic purpura in humans is a significant public health. OBJECTIVES: The aim of this study was to determine the molecular characteristics and antimicrobial resistance properties of Shiga toxigenic Escherichia coli (STEC) strains with respect to their seasonal, age and geographical distributions in Iranian pediatric patients with and without diarrhea...
October 2015: Iranian Red Crescent Medical Journal
R V Pereira, J D Siler, J C Ng, M A Davis, Y T Grohn, L D Warnick
Respiratory disease and diarrhea are the 2 most common diseases that result in the use of antimicrobial drugs in preweaned calves. Because the use of drugs in food animals, including dairy calves, has the potential for generating cross-resistance to drugs used in human medicine, it is vital to propose farm practices that foster the judicious use of antimicrobials while assuring animal health and productivity. The objective of this study was to use dairy farm calf treatment records to identify antimicrobial drug treatments in calves and to evaluate their effects on the prevalence of antimicrobial-resistant Escherichia coli from rectal swabs of preweaned dairy calves...
December 2014: Journal of Dairy Science
Azam Fatahi Sadeghabadi, Ali Ajami, Reza Fadaei, Masoud Zandieh, Elham Heidari, Mahmoud Sadeghi, Behrooz Ataei, Shervin Ghaffari Hoseini
BACKGROUND: Antibiotic resistance of enteric pathogens particularly Shigella species, is a critical world-wide problem and monitoring their resistant pattern is essential, because the choice of antibiotics is absolutely dependent on regional antibiotic susceptibility patterns. During summer 2013, an unusual increase in number of diarrheal diseases was noticed in Isfahan, a central province of Iran. Therefore, the antibiotic resistance of diarrheagenic Escherichia coli and Shigella species isolated were evaluated...
March 2014: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
Sumon Kumar Das, Shahnawaz Ahmed, Farzana Ferdous, Fahmida Dil Farzana, Mohammod Jobayer Chisti, Jonathan Ross Latham, Kaisar Ali Talukder, Mustafizur Rahman, Yasmin Ara Begum, Firdausi Qadri, Abu Syed Golam Faruque, Tahmeed Ahmed
BACKGROUND: This study compared the diversity of common diarrhoeal pathogens and antimicrobial susceptibility in four hospitals in Bangladesh. METHODOLOGY: A total of 13,959 diarrhoea patients, comprising rural Mirzapur (2,820), rural Matlab (2,865), urban Dhaka (5,287) and urban Mirpur (2,987) were included under the diarrhoeal disease surveillance system of icddr,b during 2010-2011; stool specimens were tested for Shigella spp., Vibrio cholerae, enterotoxigenic Escherichia coli and rotavirus...
December 2013: Journal of Infection in Developing Countries
Patrícia G Garcia, Vânia L Silva, Cláudio G Diniz
Acute diarrhea is a public health problem and an important cause of morbidity and mortality, especially in developing countries. The etiology is varied, and the diarrheagenic Escherichia coli pathotypes are among the most important. Our objectives were to determine the occurrence of commensal and diarrheagenic E. coli strains in fecal samples from children under five years old and their drug susceptibility patterns. E. coli were isolated from 141 fresh fecal samples; 84 were obtained from clinically injured donors with acute diarrhea (AD) and 57 from clinically healthy donors without diarrhea (WD)...
February 2011: Journal of Microbiology / the Microbiological Society of Korea
Jeannette Ouyang-Latimer, Syed Jafri, Audrey VanTassel, Zhi-Dong Jiang, Kaur Gurleen, Savio Rodriguez, Ranjan K Nandy, Thandavaryan Ramamurthy, Santanu Chatterjee, Robin McKenzie, Robert Steffen, Herbert L DuPont
The incidence rates of travelers' diarrhea (TD) have remained high for the last 50 years. More recently, there have been increasing recommendations for self-initiated therapy and use of prophylactic drugs for TD. We last examined the in vitro susceptibilities of commonly used antibiotics against TD pathogens in 1997. We now examine 456 enteropathogens isolated from adult travelers to Mexico, India, and Guatemala with diarrhea acquired between 2006 and 2008 to determine changes in susceptibility against 10 different antimicrobials by the agar dilution method...
February 2011: Antimicrobial Agents and Chemotherapy
Erick Amaya, Daniel Reyes, Samuel Vilchez, Margarita Paniagua, Roland Möllby, Carl Erik Nord, Andrej Weintraub
In developing countries, diarrhoeal diseases are one of the major causes of death in children under 5 years of age. It is known that diarrhoeagenic Escherichia coli (DEC) is an important aetiological agent of infantile diarrhoea in Nicaragua. However, there are no recent studies on antimicrobial resistance among intestinal E. coli isolates in Nicaraguan children. The aim of the present study was to determine the antimicrobial resistance pattern in a collection of 727 intestinal E. coli isolates from the faeces of children in León, Nicaragua, between March 2005 and September 2006...
February 2011: Journal of Medical Microbiology
Abdel Moati Kh Al Jarousha, Mahmoud A El Jarou, Iyad A El Qouqa
OBJECTIVE: To investigate the etiology of bacterial enteropathogens causing diarrhea among children; to elucidate the risk factors, sign and symptoms involved in developing of infection; and to identify the antimicrobial susceptibility pattern. METHODS: Stool samples from diarrheal cases with clinical diagnosis of gastroenteritis compared to matched controls, were examined for detection of bacterial enteropathogens by conventional cultural method from February 2006 through January 2007...
February 2011: Indian Journal of Pediatrics
M I Mota, M P Gadea, S González, G González, L Pardo, A Sirok, M Rivas, G Algorta, F Schelotto, G Varela
Diarrheal disease continues to be a serious health problem, especially in developing countries. Bloody diarrhea represents approximately 20-30% of all cases and has higher morbidity and mortality. Treatment with antibiotics is beneficial in cases of Shigella, Campylobacter, Yersinia and Salmonella infection, principally in those children with a higher risk of invasive disease. The aims of this study were to detect the bacterial agents associated with bloody diarrhea in children and to determine their antimicrobial susceptibility patterns...
April 2010: Revista Argentina de Microbiología
Vânia L Silva, Jacques R Nicoli, Thiago C Nascimento, Cláudio G Diniz
Urban pigeons (Columba livia) come into close contact with humans and animals, and may contribute to the spread of infectious agents. These may include human pathogens such as diarrheagenic Escherichia coli strains, which are able to survive in pigeon feces, thus creating potential for human exposure and infection. Our objectives were to determine the occurrence of diarrheagenic E. coli strains in fresh feces from urban pigeons and their drug susceptibility patterns. E. coli strains were isolated from 100 fresh feces samples and presumptive phenotypic species identification was carried out, confirmed by amplification of specific 16S ribosomal RNA encoding DNA...
September 2009: Current Microbiology
D Gendrel, R Cohen
The need to limit unnecessary antibiotic treatments and recent studies with unusual antibiotics in pediatrics (fluoroquinolones) or in digestive tract infections (azithromycin) have led to update the treatment of acute gastro-enteritis. In 2007, the European Society for Pediatric Infectious Diseases and the European Society for Gastroenterology Hepatology and Nutrition have issued guidelines. The proven shigellosis as well as the strong suspicion have to be treated promptly with antibiotics, mainly azithromycin...
October 2008: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
Mussaret B Zaidi, Verónica Leon, Claudia Canche, Carolina Perez, Shaohua Zhao, Susannah K Hubert, Jason Abbott, Karen Blickenstaff, Patrick F McDermott
OBJECTIVES: We describe the emergence and dissemination of multidrug-resistant (MDR) Salmonella Typhimurium in humans, retail meat and food animals from Yucatan, Mexico. METHODS: Salmonella Typhimurium isolates were collected through an active surveillance system and tested for susceptibility to 12 antimicrobial agents. Isolates that were non-susceptible to ceftriaxone were tested with 10 additional antimicrobials and assayed by PCR for the presence of CMY, CTX-M, SHV, TEM and OXA beta-lactamase genes...
August 2007: Journal of Antimicrobial Chemotherapy
Narcisco S Navarro, Maria I Campos, Ramon Alvarado, Nora Quintero, Frank J Branicki, Junmin Wei, Malathi Shivaprakash, France Vrijens, Hilde Giezek, Christina Y Chan, Mark J DiNubile
BACKGROUND: Prompt surgical intervention supplemented by appropriate antimicrobial therapy is usually required for successful treatment of complicated intra-abdominal infections. The objective of this study was to further evaluate the efficacy and safety of ertapenem relative to ceftriaxone/metronidazole as treatment for complicated intra-abdominal infections. METHODS: Adult patients with intra-abdominal infections requiring surgery were eligible for this open-label randomized trial comparing ertapenem 1 g daily with ceftriaxone 2 g daily plus metronidazole 30 mg/kg/day...
2005: International Journal of Surgery
Kaisar A Talukder, Abdus S Mondol, M Aminul Islam, Zhahirul Islam, Dilip K Dutta, Bijay K Khajanchi, Ishrat J Azmi, M A Hossain, M Rahman, Thomas Cheasty, Alejandro Cravioto, G B Nair, David A Sack
Every year, around 3 % of isolates from patients with diarrhoea at Dhaka Hospital, ICDDR,B, are identified as Shigella-like organisms (SLOs) based on their activity in biochemical tests. These isolates do not react with any of the current Shigella antisera including all existing and provisional serotypes. Among these SLOs, a unique cluster of seven isolates with an identical plasmid profile was found and these isolates were further characterized by phenotypic and genotypic techniques. All were nonlactose fermenters, with an identical biochemical pattern typical of Shigella dysenteriae...
May 2007: Journal of Medical Microbiology
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