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https://www.readbyqxmd.com/read/29218230/spondylodiscitis-revisited
#1
Andreas F Mavrogenis, Panayiotis D Megaloikonomos, Vasileios G Igoumenou, Georgios N Panagopoulos, Efthymia Giannitsioti, Antonios Papadopoulos, Panayiotis J Papagelopoulos
Spondylodiscitis may involve the vertebral bodies, intervertebral discs, paravertebral structures and spinal canal, with potentially high morbidity and mortality rates.A rise in the susceptible population and improved diagnosis have increased the reported incidence of the disease in recent years.Blood cultures, appropriate imaging and biopsy are essential for diagnosis and treatment.Most patients are successfully treated by conservative means; however, some patients may require surgical treatment.Surgical indications include doubtful diagnosis, progressive neurological deficits, progressive spinal deformity, failure to respond to treatment, and unresolved pain...
November 2017: EFORT Open Reviews
https://www.readbyqxmd.com/read/29215493/minimally-invasive-lateral-lumbar-interbody-fusion-for-adult-spinal-deformity-clinical-and-radiological-efficacy-with-minimum-two-years-follow-up
#2
Hyung-Youl Park, Kee-Yong Ha, Young-Hoon Kim, Dong-Gune Chang, Sang-Il Kim, Jae-Won Lee, Joo-Hyun Ahn, Jong-Bin Kim
STUDY DESIGN: A retrospective cohort study OBJECTIVE.: To evaluate the clinical and radiological efficacies of supplementing minimally invasive lateral lumbar interbody fusion (LLIF) with open posterior spinal fusion (PSF) in adult spinal deformity (ASD). SUMMARY OF BACKGROUND DATA: Minimally invasive techniques have been increasingly applied for surgery of ASD. Few reports have been published that directly compare LLIF combined with PSF to conventional PSF for ASD...
December 5, 2017: Spine
https://www.readbyqxmd.com/read/29211872/misplacement-of-stent-into-epidural-venous-plexus-with-resultant-cauda-equina-syndrome-and-open-surgical-treatment-a-case-report
#3
Benjamin B Whiting, Celene B Mulholland, Lorin Daniels, U Kumar Kakarla, Nicholas Theodore, Laura A Snyder
BACKGROUND AND IMPORTANCE: Endovascular therapy has proven to be a safe, minimally invasive treatment for multiple etiologies, but proper precautions must be taken to avoid complications. When complications occur, they should be promptly identified and corrected when possible. This case report describes endovascular stents misplaced into the epidural spinous venous plexus rather than the iliofemoral arteries, causing cauda equina syndrome, as well as the spinal procedure performed to treat the resulting spinal canal compression...
December 2, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29201845/k%C3%A3-mmell-s-disease-treated-with-percutaneous-vertebroplasty-minimum-1-year-follow-up
#4
Jae Won Park, Jong-Hwa Park, Hong Jun Jeon, Jong Young Lee, Byung Moon Cho, Se-Hyuck Park
Objective: To evaluate the radiographic and clinical outcomes of percutaneous vertebroplasty (PVP) in patients with Kümmell's disease. Methods: A retrospective review was conducted for 19 vertebrae in 18 patients, between January 2012 and June 2016. A visual analogue scale (VAS) score was used to determine each patient's subjective level of pain (0=no pain to 10=severe pain) preoperative, immediately postoperative and at the last follow-up (at least 12 months after PVP)...
October 2017: Korean Journal of Neurotrauma
https://www.readbyqxmd.com/read/29200176/anatomical-study-of-a-novel-iliosacral-screw-placement-for-sacrum-pelvis-in-adult-via-computed-tomography-reconstruction
#5
Xu Sun, Song Li, Yong Qiu, Zhonghui Chen, Xi Chen, Liang Xu, Zezhang Zhu
STUDY DESIGN: This is a cross-sectional study. OBJECTIVE: To investigate the feasibility and safety of a novel iliosacral screw placement for sacrum-pelvis in adult pelvis by computed tomography (CT) reconstruction. SUMMARY OF BACKGROUND DATA: The optimal technique of spino-pelvic fixation is still being developed and redefined. However, neither the relevant anatomic parameters nor the potential spinal canal involvement for a novel iliosacral screw placement have been clearly analyzed...
December 1, 2017: Spine
https://www.readbyqxmd.com/read/29198491/preliminary-algorithm-for-differential-diagnosis-between-spinal-meningioma-and-schwannoma-using-plain-magnetic-resonance-imaging
#6
Eiichiro Iwata, Hideki Shigematsu, Yusuke Yamamoto, Sachiko Kawasaki, Masato Tanaka, Akinori Okuda, Yasuhiko Morimoto, Keisuke Masuda, Munehisa Koizumi, Manabu Akahane, Yasuhito Tanaka
BACKGROUND: Preoperative differential diagnosis between spinal meningioma and schwannoma is critical due to the characteristic differences of the surgical treatments. Thus, we aimed to develop an algorithm for the differential diagnosis of these two lesions based on plain MRI findings. METHODS: We retrospectively reviewed plain MR images from patients who had undergone surgical treatment for meningiomas and schwannomas in our hospital between 2002 and 2016. Seven findings characteristic of meningioma or schwannoma were considered: (a) low or equal signal intensity on T2-weighted images, (b) obtuse angle from the dura mater, (c) anterior location in the spinal canal, (d) cystic degeneration, (e) lumbar occurrence, (f) oval or round shape, and (g) dumbbell type...
November 29, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29191530/acute-bilateral-isolated-foot-drop-changing-the-paradigm-in-management-of-degenerative-spine-surgery-with-percutaneous-endoscopy
#7
Nitin Adsul, Hyeun Sung Kim, Sung Ho Choi, Jee-Soo Jang, Il-Tae Jang, Seong-Hoon Oh
BACKGROUND: Acute bilateral isolated foot drop due to Lumbar disc prolapse with canal stenosis is very rare with only three cases reported in literature. Our patient was managed using the percutaneous full endoscopic technique. This is mainly to highlight the ease of access and patient outcome with pre and postoperative images to support our minimally invasive treatment for this rare condition. CASE DESCRIPTION: A 46-year-old male presented with sudden onset severe back pain with bilateral foot drop...
November 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29190788/non-invasive-assessment-of-pulsatile-intracranial-pressure-with-phase-contrast-magnetic-resonance-imaging
#8
Geir Ringstad, Erika Kristina Lindstrøm, Svein Are Sirirud Vatnehol, Kent-André Mardal, Kyrre Eeg Emblem, Per Kristian Eide
Invasive monitoring of pulsatile intracranial pressure can accurately predict shunt response in patients with idiopathic normal pressure hydrocephalus, but may potentially cause complications such as bleeding and infection. We tested how a proposed surrogate parameter for pulsatile intracranial pressure, the phase-contrast magnetic resonance imaging derived pulse pressure gradient, compared with its invasive counterpart. In 22 patients with suspected idiopathic normal pressure hydrocephalus, preceding invasive intracranial pressure monitoring, and any surgical shunt procedure, we calculated the pulse pressure gradient from phase-contrast magnetic resonance imaging derived cerebrospinal fluid flow velocities obtained at the upper cervical spinal canal using a simplified Navier-Stokes equation...
2017: PloS One
https://www.readbyqxmd.com/read/29190648/anterior-chamber-associated-immune-deviation-used-as-a-neuroprotective-strategy-in-rats-with-spinal-cord-injury
#9
Beatriz Pineda-Rodriguez, Diana Toscano-Tejeida, Elisa García-Vences, Roxana Rodriguez-Barrera, Adrian Flores-Romero, Daniela Castellanos-Canales, Gabriel Gutierrez-Ospina, Laura Castillo-Carvajal, Esperanza Meléndez-Herrera, Antonio Ibarra
The inflammatory response is probably one of the main destructive events occurring after spinal cord injury (SCI). Its progression depends mostly on the autoimmune response developed against neural constituents. Therefore, modulation or inhibition of this self-reactive reaction could help to reduce tissue destruction. Anterior chamber associated immune deviation (ACAID) is a phenomenon that induces immune-tolerance to antigens injected into the eye´s anterior chamber, provoking the reduction of such immune response...
2017: PloS One
https://www.readbyqxmd.com/read/29188210/pituitary-ependymoma-10-year-follow-up-after-partial-resection-and-radiation-therapy
#10
Jong Seok Lee, Kwan Ho Cho, Eun Kyung Hong, Sang-Hoon Shin
Ependymoma usually arises within the ventricles and central canal of the spinal cord. These tumors, found in the sellar region, are extremely rare. We report a case of pituitary ependymoma followed up over 10 years. A 59-year-old male patient presented with fatigue, general weakness, erectile dysfunction, and loss of body hair, including pubic hair. Brain magnetic resonance imaging (MRI) revealed a 3.3×3.5×2.3-cm sellar and suprasellar snowman-shaped enhancing mass. The tumor was partially resected via the trans-sphenoidal approach followed by postoperative radiation therapy...
October 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/29187689/-a-case-of-leptomeningeal-melanomatosis-with-acute-paraplegia-and-multiple-cranial-nerve-palsies
#11
Kasumi Hattori, Nozomu Matsuda, Takenobu Murakami, Eiichi Ito, Yoshikazu Ugawa
A 62-year-old man with acute paraplegia was transferred to our hospital. He had flaccid paraplegia and multiple cranial nerve palsies, such as mydriasis of the left pupil, abduction palsy of the left eye, hoarseness and dysphagia, but no meningeal irritation signs. MRI of the spinal canal showed swellings of the conus medullaris and the cauda equine, and also contrast enhancement of the spinal meninges. The cerebrospinal fluid (CSF) showed pleocytosis and protein increment. The lymph node was swollen in his right axilla...
November 28, 2017: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/29186597/factors-for-a-good-surgical-outcome-in-posterior-decompression-and-dekyphotic-corrective-fusion-with-instrumentation-for-thoracic-ossification-of-the-posterior-longitudinal-ligament-prospective-single-center-study
#12
Shiro Imagama, Kei Ando, Kazuyoshi Kobayashi, Tetsuro Hida, Kenyu Ito, Mikito Tsushima, Yoshimoto Ishikawa, Akiyuki Matsumoto, Masayoshi Morozumi, Satoshi Tanaka, Masaaki Machino, Kyotaro Ota, Hiroaki Nakashima, Yoshihiro Nishida, Yukihiro Matsuyama, Naoki Ishiguro
BACKGROUND: Surgery for thoracic ossification of the posterior longitudinal ligament (T-OPLL) is still challenging, and factors for good surgical outcomes are unknown. OBJECTIVE: To identify factors for good surgical outcomes with prospective and comparative study. METHODS: Seventy-one consecutive patients who underwent posterior decompression and instrumented fusion were divided into good or poor outcome groups based on ≥50% and <50% recovery rates for the Japanese Orthopaedic Association score...
December 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29184051/clinical-efficacy-of-anterior-partial-corpectomy-and-titanium-mesh-fusion-and-internal-fixation-for-treatment-of-old-fracture-dislocation-of-the-lower-cervical-spine
#13
De-Chao Miao, Bao-Yang Zhang, Tao Lei, Yong Shen
BACKGROUND The aim of this study was to analyze the clinical features and to evaluate the efficacy of anterior partial corpectomy and titanium mesh fusion and internal fixation of old fracture dislocation of the lower cervical spine. MATERIAL AND METHODS We retrospectively analyzed the clinical data of 52 patients with old lower cervical fracture and dislocation treated with anterior partial corpectomy and titanium mesh fusion fixation between January 2008 and December 2013, with a mean follow-up period of 4...
November 29, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29182024/first-nationwide-survey-on-systemic-wild-type-attr-amyloidosis-in-japan
#14
Yoshiki Sekijima, Masahide Yazaki, Mitsuharu Ueda, Haruki Koike, Masahito Yamada, Yukio Ando
OBJECTIVE: A nationwide survey on systemic wild-type ATTR (ATTRwt) amyloidosis was conducted to elucidate the frequency, clinical picture and possible diagnostic issues of ATTRwt amyloidosis in Japan. METHODS: A questionnaire was sent to 4629 clinical departments across Japan. A total of 2341 (50.6%) responses were returned completed for further analysis. RESULTS: Fifty-one patients with ATTRwt amyloidosis (82% male) were identified between January 2012 and December 2014...
November 28, 2017: Amyloid: the International Journal of Experimental and Clinical Investigation
https://www.readbyqxmd.com/read/29179752/characteristics-and-determinants-of-clinical-symptoms-in-radiographic-lumbar-spinal-stenosis-in-a-tertiary-health-care-centre-in-sub-saharan-africa
#15
Marie Doualla-Bija, Mbeng Ashu Takang, Emmanuella Mankaa, Jude Moutchia, Pierre Ongolo-Zogo, Henry Luma-Namme
BACKGROUND: Lumbar spinal stenosis (LSS) refers to narrowing of the lumbar central spinal canal, lateral recess, and/or neuro-foramina. Radiographic LSS plays an important role in clinical LSS but is not solely accountable for the presence of symptoms. We sought to characterise clinical LSS and to determine factors associated with presence of symptoms of LSS in patients with radiographic LSS in a sub Saharan Africa setting. METHODS: After prior ethical clearance, a case control study was done in a tertiary hospital in Douala-Cameroon, including 105 patients with radiographic LSS: 57 with symptoms of LSS (cases) and 58 with no symptoms (controls)...
November 28, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29174237/midline-ligamentum-flavum-cyst-of-the-lumbar-spine-a-case-report
#16
Kevin Shah, Daniel Segui, Sergio Gonzalez-Arias
BACKGROUND: Ligamentum flavum cysts are thought to develop due to facet joint hypermobility however the etiology of these lesions is not completely elucidated. These cysts may lead to compressive pathologies of the spine requiring surgical intervention. CASE REPORT: We report the case of a 63-year-old male with chronic back pain and progressive neurogenic claudication for 6 months. He was found to have a ligamentum flavum cyst situated along the dorsal midline of the lumbar spinal canal contributing to spinal stenosis...
November 23, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29167905/clinics-in-diagnostic-imaging-181-cervical-spine-perineural-cysts
#17
Wei Kiong Cheong, Bak Siew Steven Wong
A 47-year-old woman who underwent resection of known spinal meningioma at the T1 level returned for postoperative magnetic resonance imaging of the cervical spine. Incidentally, thin-walled structures with signal intensities that are similar to those of cerebrospinal fluid were found to be present in the left neural exit canal at the C7-T1 level and bilateral neural exit canals at the C6-7 level. Imaging findings were in keeping with perineural cysts. Cervical spine perineural cysts are likely underreported, as most of them are asymptomatic...
November 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/29165642/the-corticospinal-reserve-capacity-reorganization-of-motor-area-and-excitability-as-a-novel-pathophysiological-concept-in-cervical-myelopathy
#18
Anna Zdunczyk, Vera Schwarzer, Michael Mikhailov, Brendon Bagley, Tizian Rosenstock, Thomas Picht, Peter Vajkoczy
BACKGROUND: In degenerative cervical myelopathy (DCM), the dynamics of disease progression and the outcome after surgical decompression vary interindividually and do not necessarily correlate with radiological findings. OBJECTIVE: To improve diagnostic power in DCM by better characterization of the underlying pathophysiology using navigated transcranial magnetic stimulation (nTMS). METHODS: Eighteen patients with DCM due to cervical spinal canal stenosis were examined preoperatively with nTMS...
November 18, 2017: Neurosurgery
https://www.readbyqxmd.com/read/29164022/impact-of-baseline-magnetic-resonance-imaging-on-neurologic-functional-and-safety-outcomes-in-patients-with-acute-traumatic-spinal-cord-injury
#19
REVIEW
Shekar Kurpad, Allan R Martin, Lindsay A Tetreault, Dena J Fischer, Andrea C Skelly, David Mikulis, Adam Flanders, Bizhan Aarabi, Thomas E Mroz, Eve C Tsai, Michael G Fehlings
Study Design: Systematic review. Objective: To perform a systematic review to evaluate the utility of magnetic resonance imaging (MRI) in patients with acute spinal cord injury (SCI). Methods: An electronic search of Medline, EMBASE, the Cochrane Collaboration Library, and Google Scholar was conducted for literature published through May 12, 2015, to answer key questions associated with the use of MRI in patients with acute SCI. Results: The literature search yielded 796 potentially relevant citations, 8 of which were included in this review...
September 2017: Global Spine Journal
https://www.readbyqxmd.com/read/29163067/the-baf45d-protein-is-preferentially-expressed-in-adult-neurogenic-zones-and-in-neurons-and-may-be-required-for-retinoid-acid-induced-pax6-expression
#20
Chao Liu, Ruyu Sun, Jian Huang, Dijuan Zhang, Dake Huang, Weiqin Qi, Shenghua Wang, Fenfen Xie, Yuxian Shen, Cailiang Shen
Adult neurogenesis is important for the development of regenerative therapies for human diseases of the central nervous system (CNS) through the recruitment of adult neural stem cells (NSCs). NSCs are characterized by the capacity to generate neurons, astrocytes, and oligodendrocytes. To identify key factors involved in manipulating the adult NSC neurogenic fate thus has crucial implications for the clinical application. Here, we report that BAF45D is expressed in the subgranular zone (SGZ) of the dentate gyrus, the subventricular zone (SVZ) of the lateral ventricle, and the central canal (CC) of the adult spinal cord...
2017: Frontiers in Neuroanatomy
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