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https://www.readbyqxmd.com/read/27921070/accuracy-of-patient-specific-organ-dose-estimates-obtained-using-an-automated-image-segmentation-algorithm
#1
Taly Gilat Schmidt, Adam S Wang, Thomas Coradi, Benjamin Haas, Josh Star-Lack
The overall goal of this work is to develop a rapid, accurate, and automated software tool to estimate patient-specific organ doses from computed tomography (CT) scans using simulations to generate dose maps combined with automated segmentation algorithms. This work quantified the accuracy of organ dose estimates obtained by an automated segmentation algorithm. We hypothesized that the autosegmentation algorithm is sufficiently accurate to provide organ dose estimates, since small errors delineating organ boundaries will have minimal effect when computing mean organ dose...
October 2016: Journal of Medical Imaging
https://www.readbyqxmd.com/read/27917533/human-spinal-ejaculation-generator
#2
Clément Chéhensse, Patricia Facchinetti, Stéphane Bahrami, Philippe Andrey, Jean-Marc Soler, Fabrice Chrétien, Jacques Bernabé, Pierre Clément, Pierre Denys, François Giuliano
OBJECTIVE: A spinal ejaculation generator (SEG) has been identified in the rat with lumbar galaninergic interneurons playing a pivotal role (Science 2002;297:1566-1569). The aim was to evidence a SEG in humans. METHODS: Spatial distribution of galaninergic neurons was studied in postmortem spinal cord segments of 6 men and compared with that of 6 women for evidencing sexual dimorphism. Based on the identified segmental distribution of galaninergic neurons, the ability for penile vibratory stimulation (PVS) to elicit ejaculation when the concerned spinal segments were injured was studied in 384 patients with clinically complete spinal cord injury (SCI) and consequent anejaculation...
December 5, 2016: Annals of Neurology
https://www.readbyqxmd.com/read/27913383/traumatic-haemopneumothorax-and-whole-body-subcutaneous-emphysema-successful-use-of-a-small-bore-chest-drain
#3
Benjamin Hardy, Nicholas Sunderland, Mevan Perera, Kathryn Channing
A 56-year-old man presented having had two falls at home. He had a background of multiple sclerosis. After his second fall, during which he had fallen onto the toilet injuring his right chest, he was brought into the emergency department reporting pleuritic chest discomfort. Immediately evident was extensive swelling from his forehead to his thighs, which on palpation was found to be subcutaneous emphysema. A chest X-ray showed a large right-sided pneumothorax for which a chest drain was inserted. A CT revealed extensive surgical emphysema, pneumomediastinum, pneumoperitoneum and gas within the spinal canal...
December 2, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27904815/pneumorrhachis-resulting-in-transient-paresis-after-picc-line-insertion-into-the-ascending-lumbar-vein
#4
Russell Payne, Emily P Sieg, Arabinda Choudhary, Mark Iantosca
Obtaining intravascular access in the neonatal intensive care unit (NICU) is not only critical but also technically challenging. Malposition of the catheter tip is a known and well-documented complication. Specifically, peripherally inserted central venous catheter (PICC) line insertion into the ascending lumbar vein can lead to neurological dysfunction and, in some cases, even death. We present the first reported case of pneumorrhachis (PR) following PICC line insertion into the ascending lumbar vein. Our patient presented with lower extremity weakness and imaging confirmed the presence of air within the spinal canal...
October 17, 2016: Curēus
https://www.readbyqxmd.com/read/27904758/penetrating-thoracic-spinal-cord-injury-with-ice-pick-extending-into-the-aorta-a-technical-note-and-review-of-the-literature
#5
Rani Nasser, Jonathan Nakhla, Saadat Sharif, Merritt Kinon, Reza Yassari
BACKGROUND: Penetrating spinal cord injuries pose a great challenge to both patients and the treating physicians. Although the overall incidence of penetrating spinal cord injury is the highest in the military, the ubiquity of guns in our society continues to make penetrating spinal cord injury prevalent in the civilian population. These types of injuries are particularly complicated because, beyond the trauma to the neural elements and supporting structures, other organs can be affected and a team approach is required for successful treatment...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27904722/comparison-between-radiological-and-clinical-outcomes-of-laminoplasties-with-titanium-miniplates-for-cervical-myelopathy
#6
Jong-Hwa Park, Jae-Sung Ahn, Ho-Jin Lee, Byung-Kon Shin
BACKGROUND: Laminoplasty is a surgical procedure frequently performed for cervical myelopathy. We investigated correlations between changes in the anteroposterior diameter (APD) of the spinal canal, spinal canal area (SCA), and laminar angle (LA) and clinical outcomes of laminoplasty. METHODS: Of the 204 cervical myelopathy patients who underwent laminoplasty from July 2010 to May 2015, 49 patients who were evaluated with pre- and postoperative computed tomography of the cervical vertebrae were included...
December 2016: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/27900992/improved-intermittent-clamped-drainage-in-lower-lumbar-internal-fixation-a-randomized-prospective-study
#7
Qing-Ying Hao, Chu-Yin Liu, Chan-Juan Fu, Xiao-Hua Zhang, Ming-Sheng Tan
BACKGROUND: Continuous negative pressure drainage (CNPD) is widely used after lower lumbar internal fixation; however, it may cause tremendous blood loss and lead to postoperative hemorrhagic anemia. The present study explored the efficacy and safety of improved intermittent-clamped drainage (ICD) for lower lumbar internal fixation. METHODS: This was a prospective study that included 156 patients with decompression of the spinal canal and internal fixation for the first time from January 2012 to December 2014...
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27895949/primary-ewing-s-sarcoma-of-the-spine-in-a-two-year-old-boy
#8
Ali J Electricwala, Jaffer T Electricwala
Ewing's Sarcoma (ES) is a highly malignant bone tumour. It may involve any part of the skeleton but the most frequent parts are the ilium and diaphysis of femur and tibia (Alfeeli et al., 2005; Zhu et al., 2012). Primary ES of the spine is extremely rare (Yan et al., 2011). It accounts for only 3.5 to 14.9 percent of all primary bone sarcomas. The age of presentation ranges from 12 to 24 years (median 21 years) (Ferguson, 1999; Sharafuddin et al., 1992; Klimo Jr. et al., 2009). We report an unusual case of primary ES of the spine in a two-year-old boy, who presented to us with paraparesis and features of cauda equina syndrome...
2016: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/27889106/expression-of-the-jak-stat-signaling-pathway-in-the-ligamentum-flavum-of-patients-with-lumbar-spinal-canal-stenosis
#9
Hitoshi Yamahata, Koji Osuka, Tatsuro Aoyama, Muneyoshi Yasuda, Hiroshi Tokimura, Kazunori Arita, Masakazu Takayasu
BACKGROUND: Ligamentum flavum (LF) hypertrophy is an important cause of lumbar spinal canal stenosis (LSS), one of the most common spinal disorders in the elderly. Although many cytokines are reported to be associated with LF hypertrophy, the intracellular signaling system is rarely discussed. The purpose of this study was to identify the JAK/STAT signaling pathway and to examine the role of the JAK/STAT systems in the hypertrophied LF. METHODS: The LF of 10 LSS patients was analyzed and the expression of JAK1, STAT3, phosphorylated (p)-STAT3, and actin was examined by Western blot analysis...
November 23, 2016: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/27887879/solitary-osteochondroma-arising-in-lumbar-spinous-process-case%C3%A2-report
#10
Khaled Hadhri, Anis Tebourbi, Mehdi Saidi, Mondher Kooli
Solitary osteochondromas rarely occur in the axial skeleton. Those tumors mostly arise on the posterior elements of the cervical column causing various symptoms especially when developing within the spinal canal. Exophytic lumbar variety is uncommon presenting with palpable mass or spinal deformity. We report a 20-year-old man presenting with a solid painless mass at the lower lumbar region. Radiological examinations revealed an exophytic lesion arising in the third lumbar spinous process appearing to be a solitary osteochondroma...
November 23, 2016: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/27869435/-adolescent-idiopathic-scoliosis
#11
(no author information available yet)
Adolescent idiopathic scoliosis is a 3D spinal deformity in frontal, sagittal and axial planes, with high relevance in the pediatric population especially in adolescents and females between 10 years of age and the end of growth spurt and skeletal maturity. The radiographic manifestation is a curve greater than 10° measured by Cobb method associated with vertebral rotation. "Idiopathic" diagnosis has to be done after neuroanatomical anomalies of the posterior cerebral fosa and spinal canal have been ruled out...
December 1, 2016: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/27867442/the-slowly-enlarging-ventriculus-terminalis
#12
Joel Woodley-Cook, Magdalena Konieczny, Julian Spears
BACKGROUND: A cerebral spinal fluid (CSF) cavity within the conus medullaris has been described by the term ventriculus terminalis (VT) or the fifth ventricle. The finding of a VT on MRI imaging of the lumbar spine is often incidental but may be found in patients with low back pain or neuromuscular deficits. These lesions, when identified, are thought to regress or remain stable in terms of size, although some have been described to enlarge in the presence of post-traumatic meningeal hemorrhages or deformities of the vertebral canal...
2016: Polish Journal of Radiology
https://www.readbyqxmd.com/read/27865095/assessment-and-determinants-of-spinal-pain-in-the-course-of-disc-disorders-treated-surgically
#13
Renata Jabłońska, Robert Ślusarz, Agnieszka Królikowska, Beata Haor, Magdalena Zając
BACKGROUND Intervertebral disc disease is defined as a complex of structural changes in the aftermath of disorders of mutual elements, the structure of which form the discus intervertebralis and the spinal canal. The present work assessed pain in patients who were surgically treated due to spinal discopathy and analyzed factors that determine the condition. MATERIAL AND METHODS The research was carried on a group of 187 patients diagnosed with discopathy of the lumbosacral and cervical segment. The data are discussed in the context of medical records and the Visual Analogue Scale used for pain assessment...
November 19, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27857482/bilateral-transformational-thoracolumbar-interbody-fusion-for-the-treatment-of-giant-central-thoracolumbar-junction-disc-herniation-a-prospective-clinical-and-radiological-study
#14
Wang Wentao, Duan Kun, Liu Tuanjiang, Ma Minjie, Jiang Yong, He Baorong, Wu Qining, Liu Jijun, Hao Dingjun
STUDY DESIGN: Clinical and radiological assessment of prospective single-center data. BACKGROUND: The optimal treatment strategy for giant central thoracolumbar junction disc herniation (TLDH) remains controversial. OBJECTIVE: This study aimed to report the clinical and radiological results of bilateral transformational thoracolumbar interbody fusion (bilateral TTIF) to treat giant central TLDH. METHODS: Seventeen consecutive patients with giant central TLDH underwent bilateral TTIF from January 2014 to June 2014 and were followed for 9-15 months...
December 2016: Journal of Orthopaedics
https://www.readbyqxmd.com/read/27857459/primary-diffuse-leptomeningeal-oligodendrogliomatosis-a-case-report-and-literature-review
#15
Amarnath Chellathurai, Jay S Vaidya, Gopinathan Kathirvelu, Periakaruppan Alagappan
Primary leptomeningeal oligodendrogliomatosis (PLO) is a rare low-grade intracranial and spinal canal subarachnoid neoplasm without an obvious primary neoplasm in the brain or spinal cord parenchyma. We present here the serial progression of radiological findings of this rare disease in a 2-year-old male child whose clinical status deteriorated over a period of 4 months with the main complaint of partial seizures. During this period, the MR findings progressed from mild hydrocephalus with minimal leptomeningeal enhancement to leptomeningeal multiple cystic lesions in the entire neuraxis including the spine...
July 2016: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/27857455/imaging-in-spinal-posterior-epidural-space-lesions-a-pictorial-essay
#16
Foram B Gala, Yashant Aswani
Spinal epidural space is a real anatomic space located outside the dura mater and within the spinal canal extending from foramen magnum to sacrum. Important contents of this space are epidural fat, spinal nerves, epidural veins and arteries. Due to close proximity of posterior epidural space to spinal cord and spinal nerves, the lesions present with symptoms of radiculopathy and/or myelopathy. In this pictorial essay, detailed anatomy of the posterior epidural space, pathologies affecting it along with imaging pearls to accurately diagnose them are discussed...
July 2016: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/27856434/dynamic-contrast-enhanced-mr-perfusion-of-intradural-spinal-lesions
#17
V Cuvinciuc, M Viallon, I Barnaure, M I Vargas, K-O Lovblad, S Haller
Fifteen patients with intradural spinal lesions were examined with an optimized dynamic contrast-enhanced MR perfusion sequence at 1.5T and 3T. SNR and mean contrast-to-noise ratio were better on 3T compared with 1.5T (P ≤ .05). The goodness of fit of the Tofts and Tofts extended pharmacokinetic models was similar between 1.5T and 3T. Thus, dynamic contrast-enhanced MR perfusion of intradural spinal canal lesions is technically feasible at 1.5T and 3T, with better image quality at 3T.
November 17, 2016: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/27847574/a-comparison-of-implants-used-in-double-door-laminoplasty-allogeneic-bone-spacer-versus-hydroxyapatite-spacer
#18
Dong Yoon Lee, Chang Kyu Lee, In-Soo Kim
OBJECTIVE: The aim of this study was to compare the clinical and radiological outcomes associated with the use of hydroxyapatite (HA) spacer and allogeneic bone (AB) spacer in laminoplasty. METHODS: From January 2006 to July 2014, 79 patients with cervical spondylotic myelopathy or ossification of the posterior longitudinal ligament underwent cervical laminoplasty. The radiologic parameters were obtained from plain radiography and three-dimensional computed tomography...
November 2016: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/27845888/experimental-spinal-cord-trauma-a-review-of-mechanically-induced-spinal-cord-injury-in-rat-models
#19
Dauda Abdullahi, Azlina Ahmad Annuar, Masro Mohamad, Izzuddin Aziz, Junedah Sanusi
It has been shown that animal spinal cord compression (using methods such as clips, balloons, spinal cord strapping, or calibrated forceps) mimics the persistent spinal canal occlusion that is common in human spinal cord injury (SCI). These methods can be used to investigate the effects of compression or to know the optimal timing of decompression (as duration of compression can affect the outcome of pathology) in acute SCI. Compression models involve prolonged cord compression and are distinct from contusion models, which apply only transient force to inflict an acute injury to the spinal cord...
November 15, 2016: Reviews in the Neurosciences
https://www.readbyqxmd.com/read/27833291/a-case-report-of-acampomelic-campomelic-dysplasia-and-operative-difficulties-in-cleft-palate-reconstruction
#20
M Pasupathy, Vasant Radhakrishnan, Hirji Sorab Adenwalla, Puthucode V Narayanan
Acampomelic campomelic dysplasia (CD) is a type of CD (CD; OMIM #114290), a rare form of congenital short-limbed dwarfism and is due to mutations in SOX9 gene family. Characteristic phenotypes of CD include bowing of the lower limbs, a narrow thoracic cage, 11 pairs of ribs, hypoplastic scapulae, macrocephaly, flattened supraorbital ridges and nasal bridge, cleft palate and micrognathia. The bending of the long bones is not an obligatory feature and is absent in about 10% of cases, referred to as acampomelic CD...
May 2016: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
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