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https://www.readbyqxmd.com/read/29924047/lumbar-spinal-canal-osteosarcoma-a-case-report
#1
De-Jian Chen, Qi Lai, Jianghao Zhu, Zongmiao Wan, Hucheng Liu, Min Dai, Runsheng Guo, Bin Zhang
RATIONALE: Osteosarcoma is a rare neoplasm in the lumbar spine. Although osteosarcoma can arise in any portion of the skeleton, it very rarely arises in the spinal canal, which accounts for <0.1% of all cases of adult sarcomas. Here, we describe a case of osteosarcoma arising in the L4-5 spinal canal. PATIENT CONCERNS: The present report describes the case of a 55-year-old female patient with osteosarcoma of the L4-5 spinal canal. DIAGNOSES: The patient was initially diagnosed with lumbar spinal stenosis and underwent lumbar fusion at a local hospital...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29923980/thoracolumbar-traumatic-nucleus-pulposus-sequestration-combined-with-a-slight-flexion-distraction-fracture-a-rare-case-report-and-literature-review
#2
Ruofeng Yin, Pengyu Chang, Qingsan Zhu, Fei Cheng, Baolin Zhao, Rui Gu, Bo-Yin Zhang
RATIONALE: Traumatic nucleus pulposus sequestration (TNPS) usually occurs concurrently with severe destruction of bone. TNPS combined with a slight thoracolumbar flexion- distraction fracture, triggering a disastrous nerve injury, has rarely been reported. Due to the atypical radiologic manifestations, such a patient can easily be overlooked. PATIENT CONCERNS: Hereby, we present a TNPS patient as well as a slight thoracolumbar flexion-distraction fracture and serious neurologic symptoms...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29920290/cell-and-stage-specific-localization-of-galectin-3-a-%C3%AE-galactoside-binding-lectin-in-a-mouse-model-of-experimental-autoimmune-encephalomyelitis
#3
Tetsuya Itabashi, Yasunobu Arima, Daisuke Kamimura, Kotaro Higuchi, Yoshio Bando, Hiromi Takahashi-Iwanaga, Masaaki Murakami, Masahiko Watanabe, Toshihiko Iwanaga, Junko Nio-Kobayashi
Multiple sclerosis (MS) is an autoimmune disease in which pathogenic T cells play an important role, and an experimental autoimmune encephalomyelitis (EAE) is used as an animal model of MS. Galectins are β-galactoside-binding lectins and involved in various physiological and pathological events. Among fifteen members of galectins, galectin-1, -8, and -9 play immunosuppressive roles in MS and EAE; however, the role of galectin-3 (gal-3) is complex and controversial. We examined expression of gal-3 in the spinal cord and nerve roots of EAE mice...
June 16, 2018: Neurochemistry International
https://www.readbyqxmd.com/read/29913713/spinal-cord-stimulation-background-and-clinical-application
#4
Kaare Meier
Background Spinal cord stimulation (SCS) is a surgical treatment for chronic neuropathic pain refractory to conventional treatment. SCS treatment consists of one or more leads implanted in the epidural space of the spinal canal, connected to an implantable pulse generator (IPG). Each lead carries a number of contacts capable of delivering a weak electrical current to the spinal cord, evoking a feeling of peripheral paresthesia. With correct indication and if implanted by an experienced implanter, success rates generally are in the range of about 50-75%...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29912734/facet-joint-osteoarthritis-affects-spinal-segmental-motion-in-degenerative-spondylolisthesis
#5
Shigeyuki Kitanaka, Ryota Takatori, Yuji Arai, Masateru Nagae, Hitoshi Tonomura, Yasuo Mikami, Nozomu Inoue, Taku Ogura, Hiroyoshi Fujiwara, Toshikazu Kubo
STUDY DESIGN: This is a retrospective clinical case series (case-control study). OBJECTIVE: To clarify the influence of facet joint osteoarthritis (FJOA) on the pathology of degenerative spondylolisthesis (DS) using in vivo 3-dimensional image analysis. SUMMARY OF BACKGROUND DATA: There are no radical treatments to prevent progression of DS in patients with lumbar spinal canal stenosis associated with DS. Therefore, an effective treatment method based on the pathology of DS should be developed...
June 15, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29909552/early-outcomes-of-270-degree-spinal-canal-decompression-by-using-tessys-isee-technique-in-patients-with-lumbar-spinal-stenosis-combined-with-disk-herniation
#6
Chengjie Xiong, Tao Li, Hui Kang, Hao Hu, Jing Han, Feng Xu
PURPOSE: Traditional open approach is an efficient way to treat lumbar spinal stenosis (SS) combined with disk herniation (DH); however, risk factors such as advanced age, osteoporosis etc. are associated with the complications after the surgery. This study aims to analyze the early clinical and radiological outcomes of treatment on SS&DH by using newly developed minimal invasive TESSYS-ISEE technique. METHODS: Patients with limp and unilateral lower limb radiculopathy underwent minimal invasive surgery by using TESSYS-ISEE technique...
June 16, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29908382/open-versus-french-door-laminoplasty-for-the-treatment-of-cervical-multilevel-compressive-myelopathy-a-meta-analysis
#7
REVIEW
Wenqi Luo, Yueying Li, Jianhui Zhao, Rui Gu, Rui Jiang, Phd Feng Lin
PURPOSE: To compare the clinical outcomes and postoperative complications between open-door laminoplasty (ODL) versus French-door laminoplasty (FDL) for the treatment of cervical multilevel compressive myelopathy. METHODS: We comprehensively searched PubMed, EMBASE, Cochrane library, and China National Knowledge Infrastructure (CNKI) to identify relevant articles. The search results were last updated on January 1, 2018. All values of weighted mean difference (WMD) and odds ratio(OR) are expressed as ODL relative to FDL...
June 13, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29905520/coflex-interspinous-implant-placement-leading-to-synovial-cyst-development-case-report
#8
Seba Ramhmdani, Marc Comair, Camilo A Molina, Daniel M Sciubba, Ali Bydon
Interspinous process devices (IPDs) have been developed as less-invasive alternatives to spinal fusion with the goal of decompressing the spinal canal and preserving segmental motion. IPD implantation is proposed to treat symptoms of lumbar spinal stenosis that improve during flexion. Recent indications of IPD include lumbar facet joint syndrome, which is seen in patients with mainly low-back pain. Long-term outcomes in this subset of patients are largely unknown. The authors present a previously unreported complication of coflex (IPD) placement: the development of a large compressive lumbar synovial cyst...
June 15, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29902827/percutaneous-pedicle-lengthening-osteotomy-in-minimal-invasive-spinal-surgery-to-treat-degenerative-lumbar-spinal-stenosis-a-single-center-preliminary-experience
#9
Rosario Maugeri, Luigi Basile, Carlo Gulì, Aurelia Banco, Giovanna Giordano, Antonella Giugno, Francesca Graziano, Roberto Giuseppe Giammalva, Domenico Gerardo Iacopino
BACKGROUND:  Lumbar spinal stenosis (LSS) is a narrowing of the spinal canal due to spinal degeneration, and its main clinical symptom is neurogenic claudication. Surgical treatment is pursued for patients who do not improve with conservative care. Patients with symptomatic LSS who also have significant medical comorbidities, although clearly in need of intervention, are unattractive candidates for traditional open lumbar decompressive procedures. Thus it is important to explore minimally invasive surgical techniques to treat select patients with LSS...
June 14, 2018: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/29901623/facet-joint-hypertrophy-is-a-misnomer-a-retrospective-study
#10
Sang Joon An, Mi Sook Seo, Soo Il Choi, Tae-Ha Lim, So Jin Shin, Keum Nae Kang, Young Uk Kim
One of the major causes of lumbar spinal canal stenosis (LSCS) has been considered facet joint hypertrophy (FJH). However, a previous study asserted that "FJH" is a misnomer because common facet joints are no smaller than degenerative facet joints; however, this hypothesis has not been effectively demonstrated. Therefore, in order to verify that FJH is a misnomer in patients with LSCS, we devised new morphological parameters that we called facet joint thickness (FJT) and facet joint cross-sectional area (FJA)...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29900031/a-case-report-c2-radiculopathy-induced-by-neck-flexion-due-to-the-cord-compression-of-c2-segmental-type-vertebral-artery-relieved-by-microvascular-decompression
#11
Yuki Yamada, Yasuaki Kokubo, Kanako Kawanami, Hiroshi Itagaki, Shinji Sato, Yukihiko Sonoda
Background: Decompression of an anomalous vertebral artery (VA) may effectively treat cervical myelopathy/radiculopathy due to resultant spinal cord or nerve compression. Here we report a case of C2 radiculopathy induced by neck flexion due to cord compression of the C2 segmental type VA relieved by microvascular decompression. Case Description: A 30-year-old female presented with left occipitalgia, sensory abnormalities in the left upper and lower extremities, and neck pain induced by neck flexion...
2018: Surgical Neurology International
https://www.readbyqxmd.com/read/29896336/pneumorrhachis-with-spontaneous-pneumomediastinum-should-it-raise-special-concerns
#12
Dina Valiyakath, Thuraya Al Busaidi, Salma Al Shamsi, Yaqoob Al Sawafi
Spontaneous pneumomediastinum (SPM) is a rare and benign condition predominantly seen in young males. Patients present with non-specific pleuritic chest pain, cough, and dyspnea. Hence, it is difficult to diagnose in the acute setting until other serious differential diagnoses involving the integrity of the aerodigestive tract have been excluded. This results in over investigation and overtreatment until a diagnosis has been confirmed. We report a case of a 21-year-old Omani female who presented with a complaint of cough...
May 2018: Oman Medical Journal
https://www.readbyqxmd.com/read/29896235/curative-effect-of-posterior-lumbar-interbody-fusion-in-the-treatment-of-single-segment-lumbar-degenerative-disease-and-changes-in-adjacent-segment-quantitative-score
#13
Yan Zhuang, Feng Zhou, Yunqin Zhang, Zheng Jin
Curative effect of posterior lumbar interbody fusion (PLIF) in the treatment of single-segment lumbar degenerative disease and changes in adjacent segment quantitative score was investigated. A total of 86 patients with single-segment lumbar degenerative disease were randomly selected and divided into control group (n=43) and observation group (n=43). The control group was treated with posterolateral lumbar fusion, while the observation group was treated with PLIF. The observation group had a significantly longer operation time and shorter hospitalization time compared with the control group (P<0...
July 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29892257/focused-neuro-otological-review-of-superficial-siderosis-of-the-central-nervous-system
#14
Aran Yoo, Jonathan Jou, Jeffrey D Klopfenstein, Jorge C Kattah
Background: Infratentorial siderosis (iSS) is a progressive degenerative disorder targeting primarily the cerebellum and cranial nerve eighth; therefore, progressive ataxia and its neuro-otological findings are common. Toxicity from hemosiderin involves selectively vulnerable neurons and glia in these posterior fossa structures. Other neurologic findings may be present, though our focus relates to the cochlea-vestibular cerebellar involvement. Radiographic evidence of siderosis may be the result of recurrent, albeit covert bleeding in the subarachnoid space, or the consequence of an overt post-traumatic or aneurysmal subarachnoid hemorrhage (SAH)...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29891676/wnt-%C3%AE-catenin-signaling-regulates-ependymal-cell-development-and-adult-homeostasis
#15
Liujing Xing, Teni Anbarchian, Jonathan M Tsai, Giles W Plant, Roeland Nusse
In the adult mouse spinal cord, the ependymal cell population that surrounds the central canal is thought to be a promising source of quiescent stem cells to treat spinal cord injury. Relatively little is known about the cellular origin of ependymal cells during spinal cord development, or the molecular mechanisms that regulate ependymal cells during adult homeostasis. Using genetic lineage tracing based on the Wnt target gene Axin2 , we have characterized Wnt-responsive cells during spinal cord development...
June 11, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29890965/intradural-extramedullary-tumor-in-the-stenotic-cervical-spine-resected-through-open-door-laminoplasty-with-hydroxyapatite-spacers-report-of-two-cases
#16
Naohisa Miyakoshi, Daisuke Kudo, Michio Hongo, Yuji Kasukawa, Yoshinori Ishikawa, Yoichi Shimada
BACKGROUND: Safe excision of spinal cord tumors depends on sufficient visualization of the tumor and surrounding structures. In patients with spinal cord tumor adjacent to a stenotic spinal canal, extensive bony decompression proximal and distal to the tumor should be considered for safer excision of the tumor. Extensive wide laminectomy is one choice for such cases, but postoperative problems such as kyphotic deformity remain a concern. CASE PRESENTATION: A 76-year-old man and a 60-year-old woman presented with symptomatic intradural extramedullary spinal cord tumors in the cervical spine...
June 11, 2018: BMC Surgery
https://www.readbyqxmd.com/read/29890541/percutaneous-instrumentation-of-a-complex-lumbar-spine-fracture-with-bilateral-pedicle-dissociation-case-report-and-technical-note
#17
Evan Luther, Timur Urakov, Steven Vanni
BACKGROUND AND STUDY OBJECTIVE:  Complex traumatic lumbar spine fractures are difficult to manage and typically occur in younger patients. Surgical immobilization for unstable fractures is an accepted treatment but can lead to future adjacent-level disease. Furthermore, large variations in fracture morphology create significant difficulties when attempting fixation. Therefore, a surgical approach that considers both long-term outcomes and fracture type is of utmost importance. We present a novel technique for percutaneous fixation without interbody or posterolateral fusion in a young patient with bilateral pedicle dissociations and an acute-onset incomplete neurologic deficit...
June 11, 2018: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/29888399/localization-of-the-motor-neuron-somata-of-geniohyoid-muscle-in-rat-a-horseradish-peroxidase-study
#18
Aimi Nadia Binti Razlan, Muzammil Ullah, Marina Yurievna Kapitonova, Norhayati Binti Liaqat Ali Khan, Syed Baharom Syed Ahmad Fuad
The aim of the study was to investigate the location of motor neuron somata of geniohyoid muscle in rat. Nine Sprague-Dawley rats were used in this study. Operations were performed under general anaesthesia. Nembutal sodium, 40 mg per kg intraperitoneally was used for anaesthesia. 0.02 to 0.05 ml of 30% horseradish peroxidase (Sigma Type VI) solution in normal saline was injected into the exposed right geniohyoid muscle. After 48 hr, the animals were fixed by perfusion through left ventricle of heart, first by 100 ml normal saline and then with 500 ml of 1...
June 11, 2018: Anatomia, Histologia, Embryologia
https://www.readbyqxmd.com/read/29884775/a-novel-extradural-nerve-transfer-technique-by-coaptation-of-c4-to-c5-and-c7-to-c6-for-treating-isolated-upper-trunk-avulsion-of-the-brachial-plexus
#19
Kai-Xiang Yang, Shao-Hua Zhang, Da-Wei Ge, Tao Sui, Hong-Tao Chen, Xiao-Jian Cao
The study aimed to demonstrate the feasibility of an extradural nerve anastomosis technique for the restoration of a C5 and C6 avulsion of the brachial plexus. Nine fresh frozen human cadavers were used. The diameters, sizes, and locations of the extradural spinal nerve roots were observed. The lengths of the extradural spinal nerve roots and the distance between the neighboring nerve root outlets were measured and compared in the cervical segments. In the spinal canal, the ventral and dorsal roots were separated by the dura and arachnoid...
June 8, 2018: Journal of Biomedical Research
https://www.readbyqxmd.com/read/29883829/minimally-invasive-translaminar-endoscopic-approach-to-percutaneous-vertebroplasty-cement-leakage-technical-note
#20
Goktug Akyoldas, Salim Şenturk, Ülkün Ünlü Ünsal, Onur Yaman, Ali Fahir Özer
BACKGROUND: Percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) are two common procedures that could be applied simply in treatment of vertebral compression fractures (VCFs). Despite simplicity and safe application of these procedures, there are some drawbacks as well. The cement leakage into spinal canal is mostly seen complication of PVP and PKV procedures. The aim of this article is to present a minimally invasive alternative technique for removing cement leakage fragment after the PVP...
June 5, 2018: World Neurosurgery
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