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https://www.readbyqxmd.com/read/28212784/intraspinal-extradural-variations-of-nerve-roots
#1
Viktor Matejčík, Zora Haviarová, Andrej Šteňo, Roman Kuruc, Juraj Šteňo
INTRODUCTION: The aim of this work is to point out the intraspinal extradural anatomical variations of nerve roots and their possible participation in radiculopathy. METHODS: The anatomical study was performed in 33 cadavers at a mean age of 46.5 and up to 24h from death. All extradural anastomoses between nerve roots were excised and examined histologically for the presence or absence of nervous tissue. The type of the plexus was defined by subtracting from the root C2...
February 14, 2017: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/28207618/magnetic-resonance-imaging-evaluation-of-the-effects-of-surgical-invasiveness-on-paravertebral-muscles-after-muscle-preserving-interlaminar-decompression-mild
#2
Hitoshi Tonomura, Yoichiro Hatta, Yasuo Mikami, Takumi Ikeda, Tomohisa Harada, Masateru Nagae, Hironori Koike, Hitoshi Hase, Toshikazu Kubo
STUDY DESIGN: This is a retrospective study. OBJECTIVES: The aim of this study was to determine the extent of damage to the paravertebral muscles after muscle-preserving interlaminar decompression (MILD) using magnetic resonance imaging to evaluate changes in the multifidus muscle (MF). SUMMARY OF BACKGROUND DATA: Short-term surgical outcomes of MILD for lumbar spinal canal stenosis (LSCS) are satisfactory; however, the extent of damage to the paravertebral muscles after MILD remains unclear...
March 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28187870/the-unique-organization-of-filamentous-actin-in-the-medullary-canal-of-the-medulla-oblongata
#3
Bai-Hong Tan, Chun-Yan Guo, Tian-Qing Xiong, Ling-Meng Chen, Yan-Chao Li
In the central canal, F-actin is predominantly localized in the apical region, forming a ring-like structure around the circumference of the lumen. However, an exception is found in the medulla oblongata, where the apical F-actin becomes interrupted in the ventral aspect of the canal. To clarify the precise localization of F-actin, the fluorescence signals for F-actin were converted to the peroxidase/DAB reaction products in this study by a phalloidin-based ultrastructural technique, which demonstrated that F-actin is located mainly in the microvilli and terminal webs in the ependymocytes...
January 24, 2017: Tissue & Cell
https://www.readbyqxmd.com/read/28187077/comparison-of-synchrotron-radiation-based-propagation-phase-contrast-imaging-and-conventional-micro-computed-tomography-for-assessing-intervertebral-discs-and-endplates-in-a-murine-model
#4
Jianzhong Hu, Shuangfei Ni, Yong Cao, Xiaokai Wang, Shenghui Liao, Hongbin Lu
STUDY DESIGN: The synchrotron radiation based micro-CT (SRμCT) and micro-CT (μCT) were applied to comparatively assess the intervertebral disc (IVD) and endplate (EP). OBJECTIVE: To explore a new approach to evaluate the detailed structure of the IVD and EP during maturation and aging in a murine model. SUMMARY OF BACKGROUND DATA: To date, methods to observe the morphological changes in the IVD and EP from rodent have been relatively limited...
February 9, 2017: Spine
https://www.readbyqxmd.com/read/28187068/ct-based-three-dimensional-measurements-of-spine-shortening-distance-after-posterior-three-column-osteotomies-for-the-treatment-of-severe-and-stiff-scoliosis
#5
Xue-Shi Li, Zi-Fang Huang, Yao-Long Deng, Heng-Wei Fan, Wen-Yuan Sui, Chong-Wen Wang, Jun-Lin Yang
STUDY DESIGN: Retrospective Study. OBJECTIVES: This study is to measure and analyze the changes of three-dimensional distances of spinal column and spinal canal at the three-column osteotomy sites and address their clinical and neurologic significance. SUMMARY OF BACKGROUND DATA: Three-column osteotomies were developed to treat severe and stiff spine deformities with insufficient understanding on the safe limit of spine shortening and the relationship between the shortening distance of the spinal column and that of the spinal canal...
February 9, 2017: Spine
https://www.readbyqxmd.com/read/28180981/does-pre-operative-magnetic-resonance-imaging-of-the-lumbar-multifidus-muscle-predict-clinical-outcomes-following-lumbar-spinal-decompression-for-symptomatic-spinal-stenosis
#6
Mario G T Zotti, F Vilas Boas, T Clifton, M Piche, W W Yoon, B J C Freeman
PURPOSE: To investigate whether pre-operative magnetic resonance imaging (MRI) of the lumbar multifidus muscle (LMM) would predict clinical outcomes following lumbar spinal decompression for symptomatic spinal stenosis. METHODS: A prospective cohort of patients with symptomatic neurogenic claudication, documented spinal stenosis on pre-operative MRI underwent spinal decompression. All subjects completed standardised outcome measures (Core Outcome Measures Index (COMI), Oswestry Disability Index (ODI v2...
February 8, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28169956/thoracic-spine-growth-re-visited-how-accurate-is-the-dimeglio-data
#7
Ozgur Dede, Kadir Büyükdoğan, Halil Gökhan Demirkran, Erhan Akpnar
STUDY DESIGN: Cross Sectional Descriptive Study OBJECTIVE.: To describe the normal rate pattern of thoracic spine growth in children without any spinal deformity. SUMMARY OF BACKGROUND DATA: The knowledge of thoracic spine growth and height is important for growing spine treatment and the decision of final fusion. Currently pediatric spinal deformity is approached as early onset and late onset with an understanding of the fast growth during the first five years of life...
February 6, 2017: Spine
https://www.readbyqxmd.com/read/28168635/imaging-of-post-surgical-treatment-and-of-related-complications-in-spinal-trauma
#8
REVIEW
F Caranci, G Leone, L Ugga, E Cesarano, R Capasso, S Schipani, A Bianco, P Fonio, F Briganti, L Brunese
Spinal trauma is a devastating event with a high morbidity and mortality. The rationale of imaging is to diagnose the traumatic abnormalities and characterize the type of injury, to estimate the severity of the lesions, to evaluate the potential spinal instability. In case of spinal instability, the goals of operative treatment are decompression of the spinal cord canal and stabilization of the disrupted vertebral column. Particularly, diagnostic imaging, mainly by CT and MR, has a main role in the post-treatment evaluation...
February 6, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/28163949/anterior-to-posterior-migration-of-a-lumbar-disc-sequestration-surgical-remarks-and-technical-notes-about-a-tailored-microsurgical-discectomy
#9
Alessandro Frati, Alessandro Pesce, Mauro Palmieri, Tommaso Vangelista, Riccardo Caruso, Maurizio Salvati, Antonino Raco
Extrusion of disc material within the spinal canal complicates up to 28.6% of lumbar disc herniations. Due to the anatomical "corridors" created by the anterior midline septum and lateral membranes, relocation occurs with an anterior and anterolateral axial topography. Posterior migration is an extremely rare condition and anterior-to-posterior circumferential migration is an even rarer condition. Its radiological feature can be enigmatic and since, in more than 50% of cases, clinical onset is a hyperacute cauda equina syndrome, it may imply a difficult surgical decision in emergency settings...
2017: Case Reports in Surgery
https://www.readbyqxmd.com/read/28163505/the-association-between-sagittal-index-canal-compromise-loss-of-vertebral-body-height-and-severity-of-spinal-cord-injury-in-thoracolumbar-burst-fractures
#10
Mehmet Onur Yüksel, Mehmet Sabri Gürbüz, Şevki Gök, Numan Karaarslan, Merih İş, Mehmet Zafer Berkman
AIM: Our aim was to determine whether a combination of sagittal index (SI), canal compromise (CC), and loss of vertebral body height (LVBH) is associated with the severity of neurological injury in patients with thoracolumbar burst fractures. MATERIALS AND METHODS: Seventy-four patients with thoracolumbar burst fracture undergoing instrumentation between 2010 and 2015 were analyzed retrospectively. The degree of neurological injury was determined using the American Spinal Injury Association (ASIA) scoring system...
December 2016: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28160397/alternate-intraspinal-targets-for-spinal-cord-stimulation-a-systematic-review
#11
REVIEW
George C Chang Chien, Nagy Mekhail
BACKGROUND: Conventional dorsal column spinal cord stimulation (SCS) provides less than optimal pain relief for certain pain syndromes and anatomic pain distributions. Practitioners have sought to treat these challenging therapeutic areas with stimulation of alternate intraspinal targets. OBJECTIVE: To identify and systematically review the evidence for the value neuromodulating specific neuronal targets within the spinal canal to achieve relief of chronic pain...
February 3, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28156203/feasibility-of-iterative-model-reconstruction-for-unenhancedlumbar-ct
#12
Yuji Iyama, Takeshi Nakaura, Ayumi Iyama, Masafumi Kidoh, Kazuhiro Katahira, Seitaro Oda, Daisuke Utsunomiya, Yasuyuki Yamashita
Purpose To evaluate the image quality and interobserver reproducibility of unenhanced lumbar spinal computed tomography (CT) images reconstructed with iterative model reconstruction (IMR). Materials and Methods This prospective study was approved by the local ethics committee, and written informed consent was obtained from all patients. The study included 34 patients scanned with unenhanced CT and magnetic resonance (MR) imaging for lumbar canal spinal stenosis. The CT images were reconstructed with filtered back projection (FBP), hybrid iterative reconstruction (HIR), and IMR...
February 2, 2017: Radiology
https://www.readbyqxmd.com/read/28153620/potential-and-limitations-of-neural-decompression-in-extreme-lateral-interbody-fusion-a-systematic-review
#13
REVIEW
Gernot Lang, Moritz Perrech, Rodrigo Navarro-Ramirez, Ibrahim Hussain, Brenton Pennicooke, Farah Maryam, Mauricio J Avila, Roger Hartl
BACKGROUND: Extreme lateral interbody fusion (ELIF) is a powerful tool for interbody fusion and coronal deformity correction. However, evidence regarding the success of ELIF in decompressing foraminal, lateral recesses and central canal stenosis is lacking. The purpose of this study was to systematically review current literature on the potential and limitations of ELIF to indirectly decompress neural elements. METHODS: A systematic literature search in the PubMed, Cochrane and ScienceDirect databases was performed according to PRISM criteria...
January 30, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28151906/mini-plate-fixation-versus-suture-suspensory-fixation-in-cervical-laminoplasty-a-meta-analysis
#14
Feng-Yu Liu, Lei Ma, Li-Shuang Huo, Yan-Xiang Cao, Da-Long Yang, Hui Wang, Si-Dong Yang, Wen-Yuan Ding
BACKGROUND: Both the mini-plate fixation and suture suspensory fixation techniques are extensively applied in cervical laminoplasty, but which technique is superior has not been ascertained. The purpose of this meta-analysis is to compare the results between mini-plate fixation and suture suspensory fixation in cervical laminoplasty for the patients with multilevel cervical compressive myelopathy. METHODS: PubMed, Embase, the Cochrane library, CNKI, and WANFANG were searched for studies that compared mini-plate fixation and suture suspensory fixation in cervical laminoplasty up to November 1, 2016...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28145426/two-novel-bmp-2-variants-identified-in-patients-with-thoracic-ossification-of-the-ligamentum-flavum
#15
Xiaochen Qu, Zhongqiang Chen, Dongwei Fan, Shen Xiang, Chuiguo Sun, Yan Zeng, Weishi Li, Zhaoqing Guo, Qiang Qi, Woquan Zhong, Yun Jiang
Thoracic ossification of the ligamentum flavum (TOLF)is a common cause of thoracic spinal canal stenosis and has been reported almost exclusively in East Asian countries. In this study, we established a relationship between bone morphogenic protein 2 (BMP-2) and TOLF. We divided patients into two groups according to severity of ossification and identified susceptible loci through exome sequencing. We identified 39 novel likely pathogenic variants in 29 genes in the transforming growth factor-beta (TGF-β) superfamily or TGF-β/BMPs signaling pathway, including two missense variants in BMP-2 (NM_001200...
February 1, 2017: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/28144987/prevalence-and-risk-factors-for-presumptive-ascending-descending-myelomalacia-in-dogs-after-thoracolumbar-intervertebral-disk-herniation
#16
F Balducci, S Canal, B Contiero, M Bernardini
BACKGROUND: Ascending/descending myelomalacia (ADMM) is a severe complication of thoracolumbar intervertebral disk herniation (TL-IVDH) in dogs. HYPOTHESIS/OBJECTIVES: To investigate the prevalence and risk factors for ADMM in nonambulatory dogs with surgically treated TL-IVDH. ANIMALS: Six-hundred and fifty-two client-owned dogs evaluated for TL-IVDH that underwent decompressive spinal surgery. METHODS: Retrospective medical record review from February 2007 through December 2015...
February 1, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28143552/abscess-of-the-cervical-spine-secondary-to-injection-site-infection-in-a-heifer
#17
Ueli Braun, Christian Gerspach, Karolin Kühn, Julia Bünter, Monika Hilbe
BACKGROUND: Abscesses in the neck region can result from infection associated with injection of drugs into the neck muscles. To our knowledge, there have been no reports of osteomyelitis of the cervical vertebra and spinal cord compression secondary to an abscess in the neck. This case report describes the findings in a 9.5-month-old heifer with an abscess of the cervical spine secondary to injection site infection. CASE PRESENTATION: The main clinical findings were swelling on the left side of the neck, proprioceptive deficits in all limbs and generalised ataxia...
January 31, 2017: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/28137972/identification-of-the-upward-movement-of-human-cerebrospinal-fluid-in-vivo-and-its-relation-to-the-brain-venous-system
#18
Steffi Dreha-Kulaczewski, Arun A Joseph, Klaus-Dietmar Merboldt, Hans-Christoph Ludwig, Jutta Gärtner, Jens Frahm
: Cerebrospinal fluid (CSF) flux is involved in the pathophysiology of neurodegenerative diseases and cognitive impairment after traumatic brain injury, all hallmarked by the accumulation of cellular metabolic waste. Its effective disposal via various CSF routes has been demonstrated in animal models. In contrast, the CSF dynamics in humans are still poorly understood. Forced Inspiration has recently been identified as a main driving force of CSF flow in the human brain using novel real-time magnetic resonance imaging (MRI)...
January 30, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28130164/does-dynamic-supine-magnetic-resonance-imaging-improve-the-diagnostic-accuracy-of-cervical-spondylotic-myelopathy-a-review-of-the-current-evidence
#19
REVIEW
Nanfang Xu, Shaobo Wang, Huishu Yuan, Xiaoguang Liu, Zhongjun Liu
PURPOSE: We aimed to critically analyze the current evidence regarding the role of dynamic supine MRI (dsMRI) in the evaluation of cervical spondylotic myelopathy (CSM). METHODS: 13 studies were identified through a comprehensive literature search performed in the PubMed, EMBASE, and ISI databases as fulfilling the inclusion criteria and were reviewed for subject characteristics, radiographical parameters, and salient findings. RESULTS: Studies herein reviewed suggested that dsMRI was able to detect new appearance or increased grade of medullary compression in at least 20% of patients and to demonstrate an average narrowing of the cervical canal by 20% (in comparison to the neutral position)...
January 24, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28125937/thoracic-compression-myelopathy-due-to-the-progression-of-dystrophic-scoliosis-the-presence-of-a-paraspinal-tumor-and-high-and-excessive-amplitude-movement-of-the-shoulder
#20
Takashi Kurosawa, Takashi Yurube, Kenichiro Kakutani, Koichiro Maeno, Koki Uno, Masahiro Kurosaka, Kotaro Nishida
The authors present a case of 45-year-old man with neurofibromatosis type 1 (NF-1) and thoracic scoliosis, previously undergoing fusion surgery, who developed myelopathy. This patient further complained of lightning pain when he extended and horizontally abducted the convex-side shoulder. Radiological examination revealed the progression of dystrophic scoliosis with opened spinal canals and the presence of a neurofibroma behind the spinal cord at the apical levels. Delayed development of spinal instability can occur due to dystrophy even postoperatively in patients with NF-1...
January 2017: Journal of Orthopaedic Surgery
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