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https://www.readbyqxmd.com/read/29786593/reproductive-function-the-protection-of-the-rights-of-the-people-which-are-sent-to-the-area-of-the-fighting
#1
Vitalii Pashkov, Nataliya Gutorova, Petro Noha
OBJECTIVE: Introduction: The issues of problems of the legal regulation of posthumous reproduction in Ukraine and foreign countries are analysis in the article. The author substantiates the necessity in the creation and acceptance of the State Program of the retrieval of reproductive cells in people who are sending to the area of the fighting. The aim:the purpose of our work is a comprehensive study of post-mortem (post-mortem) reproduction and substantiation of the possibility and necessity of adopting a state program for the selection of reproductive cells of individuals who are sent to a combat zone to ensure their full social protection and assistance in the realization of the right to fatherhood or motherhood...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29786117/the-relevance-of-the-hippocratic-oath-to-the-ethical-and-moral-values-of-contemporary-medicine-part-ii-interpretation-of-the-hippocratic-oath-today-s-perspective
#2
REVIEW
Helen Askitopoulou, Antonis N Vgontzas
This is the second part of a paper on the relevance and significance of the Hippocratic Oath to modern medical ethical and moral values with the aim at answering questions on controversial issues related to the Oath. Part I argued that the general attributes and ethical values of the Oath are relevant to the modern world. Part II attempts to elucidate the interpretation of the specific injunctions of the Oath from today's perspective in relation to ethical values concerning the duties of physicians to patients and society...
May 21, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29784820/efficient-collective-swimming-by-harnessing-vortices-through-deep-reinforcement-learning
#3
Siddhartha Verma, Guido Novati, Petros Koumoutsakos
Fish in schooling formations navigate complex flow fields replete with mechanical energy in the vortex wakes of their companions. Their schooling behavior has been associated with evolutionary advantages including energy savings, yet the underlying physical mechanisms remain unknown. We show that fish can improve their sustained propulsive efficiency by placing themselves in appropriate locations in the wake of other swimmers and intercepting judiciously their shed vortices. This swimming strategy leads to collective energy savings and is revealed through a combination of high-fidelity flow simulations with a deep reinforcement learning (RL) algorithm...
May 21, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29781998/making-testing-and-using-potassium-ion-selective-microelectrodes-in-tissue-slices-of-adult-brain
#4
J Christopher Octeau, Guido Faas, Istvan Mody, Baljit S Khakh
Potassium ions significantly contribute to the resting membrane potential of cells and, therefore, extracellular K+ concentration is a crucial regulator of cell excitability. Altered concentrations of extracellular K+ affect the resting membrane potential and cellular excitability by shifting the equilibria between closed, open and inactivated states for voltage-dependent ion channels that underlie action potential initiation and conduction. Hence, it is valuable to directly measure extracellular K+ dynamics in health and diseased states...
May 7, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29781395/judicialization-2-0-understanding-right-to-health-litigation-in-real-time
#5
João Biehl, Mariana P Socal, Varun Gauri, Debora Diniz, Marcelo Medeiros, Gabriela Rondon, Joseph J Amon
Over the past two decades, debate over the whys, the hows, and the effects of the ever-expanding phenomenon of right-to-health litigation ('judicialization') throughout Latin America have been marked by polarised arguments and limited information. In contrast to claims of judicialization as a positive or negative trend, less attention has been paid to ways to better understand the phenomenon in real time. In this article, we propose a new approach-Judicialization 2.0-that recognises judicialization as an integral part of democratic life...
May 21, 2018: Global Public Health
https://www.readbyqxmd.com/read/29780658/the-selective-labels-problem-evaluating-algorithmic-predictions-in-the-presence-of-unobservables
#6
Himabindu Lakkaraju, Jon Kleinberg, Jure Leskovec, Jens Ludwig, Sendhil Mullainathan
Evaluating whether machines improve on human performance is one of the central questions of machine learning. However, there are many domains where the data is selectively labeled in the sense that the observed outcomes are themselves a consequence of the existing choices of the human decision-makers. For instance, in the context of judicial bail decisions, we observe the outcome of whether a defendant fails to return for their court appearance only if the human judge decides to release the defendant on bail...
August 2017: KDD: Proceedings
https://www.readbyqxmd.com/read/29777601/-informed-consent-something-unresolved-in-the-penitentiary-setting
#7
Julio García Guerrero
INTRODUCTION: The exercise of Informed Consent within the penitentiary environment contradicts the ordinary exercise of the same towards the rest of the population. METHODOLOGY: review of legal regulations and constitutional doctrine on IC. Review of the judicial outcomes when a prisoner refuses medical treatment. RESULTS: Normative on IC (Ley 41/2002 y Convenio de Oviedo, Spanish legal framework): with the exception of cases in which IC cannot be taken or under the risk of causong damage to third parties, competent and capable persons can decide over their life and health, and such decisions need to be respected...
May 2018: Cuadernos de Bioética: Revista Oficial de la Asociación Española de Bioética y Ética Médica
https://www.readbyqxmd.com/read/29770051/agriculture-and-agri-food-canada-s-research-program-on-antimicrobial-resistance
#8
E Topp
A key strategy for attenuating the development of antimicrobial resistance (AMR) is ensuring judicious use of antimicrobials in human and veterinary medicine and in agriculture. Research on AMR in agriculture includes risk assessment, risk management, and identifying the role of agricultural practices in development of AMR. Risk assessment includes an impact assessment of antimicrobial use in livestock and on the environment; for example, many antimicrobials are excreted unchanged and thus reach the environment through manure application...
November 2, 2017: Canada Communicable Disease Report, Relevé des Maladies Transmissibles Au Canada
https://www.readbyqxmd.com/read/29768992/the-effect-of-sex-and-perpetrator-victim-relationship-on-perceptions-of-domestic-homicide
#9
Linda C Karlsson, Tuulia Malén, Johanna K Kaakinen, Jan Antfolk
Previous research on how stereotypes affect perceptions of intimate partner violence and domestic homicide has found that violence committed by men is perceived as more severe and judged more harshly than violence committed by women. The present mock jury study investigated how perpetrator sex (male or female), crime type (familicide or filicide), and relatedness between perpetrator and child victims (biological or step) affect laypeople's perceptions of the appropriate consequence of the crime, the reason for the offense, responsibility of the perpetrator, the likelihood of certain background factors being present, and the risk of future violence...
May 1, 2018: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29765295/incentives-for-blood-donation-a-discrete-choice-experiment-to-analyze-extrinsic-motivation
#10
Andrew Sadler, Ling Shi, Susanne Bethge, Axel Mühlbacher
Background: Demographic trends affect size and age structure of populations. One of the consequences will be an increasing need for blood products to treat age-related diseases. Donation services rely on voluntariness and charitable motivation. It might be questioned whether there will be sufficient blood supply with voluntary donation. The present study focused on elicitation of preferences for incentives and aimed to contribute to the discussion on how to increase donation rates. Methods: A self-administered discrete choice experiment (DCE) was applied...
April 2018: Transfusion Medicine and Hemotherapy
https://www.readbyqxmd.com/read/29763689/surface-engineered-excipients-ii-simultaneous-milling-and-dry-coating-for-preparation-of-fine-grade-microcrystalline-cellulose-with-enhanced-properties
#11
Liang Chen, Xiaoyi Ding, Zizhou He, Siqi Fan, Kuriakose T Kunnath, Kai Zheng, Rajesh N Davé
A solventless process for simultaneously milling and dry coating microcrystalline cellulose (MCC) was investigated for producing fine excipients in five different sizes (∼20, 25, 30, 35, 40µm) having high bulk density (BD), good flow function coefficient (FFC), and excellent compaction. Avicel PH-102, used as the starting material, was milled and coated with two grades of silicas, hydrophobic and hydrophilic (R972P and A200), using a fluid energy mill (FEM). Through judicious selection of the FEM feed rate, feeding pressure, and grinding pressure, five desired milled sizes were produced...
May 12, 2018: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29757716/us-assessment-of-sports-related-hip-injuries
#12
Eugen Lungu, Johan Michaud, Nathalie J Bureau
Traumatic and overuse hip injuries occur frequently in amateur and professional athletes. After clinical assessment, imaging plays an important role in diagnosis and in defining care management of these injuries. Ultrasonography (US) is being increasingly used in assessment of hip injuries because of the wide availability of US machines, the lower cost, and the unique real-time imaging capability, which allows both static and dynamic evaluation as well as guidance of point-of-care interventions such as fluid aspiration and steroid injection...
May 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29757637/peptide-sequence-and-solvent-as-levers-to-control-disulfide-connectivity-in-multiple-cysteine-containing-venom-toxins
#13
Karuna Anna Sajeevan, Durba Roy
Judicious choice of solvent, temperature and strategic mutations along a peptide backbone can minimize formation of non-native disulfide bond isoforms in chemical synthesis of multiple cysteine containing venom toxins. By exploiting these controls, one can drive the population distribution in favor of a particular isoform. Some chosen ionic liquids (ILs), like 1-ethyl-3-methyl-imidazolium acetate, [Im21][OAc], have proven efficient in favoring the native globular isoform in some conotoxins. To comprehend such a preference, we report an explicit solvent replica exchange molecular dynamics (REMD) study of two conotoxins, AuIB and GI, solvated in either neat water or ~50% (v/v) mixture of water-[Im21][OAc]...
May 14, 2018: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/29756000/bullous-fixed-drug-eruption-following-ibuprofen-ingestion
#14
Seyed Amirhossein Fazeli, Morteza Abbasi, Hadi Jalali, Sonia Eskandari, Farzaneh Shamshirgaran, Zahra Dehghani, Reza Golabchifard, Shahram Ghiyasvand, Kaveh Ghannad
Fixed drug eruption (FDE) is a drug reaction involving skin and less commonly mucosal membranes. The common manifestation is localized well-demarcated patches or plaques appeared following receiving of a culprit drug. When re-exposure occurs, the rashes will appear at areas involved in previous episodes. Limited reports on bullous FDE due to ibuprofen have been documented before. Herein, we described an elderly man who experienced multifocal lesions in his oral mucosa, penis, and multiple sites of skin following ibuprofen ingestion confirmed as FDE by pathological studies...
January 2018: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/29754440/indications-and-interpretation-of-esophageal-function-testing
#15
REVIEW
C Prakash Gyawali, Nicola de Bortoli, John Clarke, Carla Marinelli, Salvatore Tolone, Sabine Roman, Edoardo Savarino
Esophageal symptoms are common, and can arise from mucosal, motor, functional, and neoplastic processes, among others. Judicious use of diagnostic testing can help define the etiology of symptoms and can direct management. Endoscopy, esophageal high-resolution manometry (HRM), ambulatory pH or pH-impedance manometry, and barium radiography are commonly used for esophageal function testing; functional lumen imaging probe is an emerging option. Recent consensus guidelines have provided direction in using test findings toward defining mechanisms of esophageal symptoms...
May 12, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29749387/invasive-candidiasis
#16
REVIEW
Peter G Pappas, Michail S Lionakis, Maiken Cavling Arendrup, Luis Ostrosky-Zeichner, Bart Jan Kullberg
Invasive candidiasis is an important health-care-associated fungal infection that can be caused by several Candida spp.; the most common species is Candida albicans, but the prevalence of these organisms varies considerably depending on geographical location. The spectrum of disease of invasive candidiasis ranges from minimally symptomatic candidaemia to fulminant sepsis with an associated mortality exceeding 70%. Candida spp. are common commensal organisms in the skin and gut microbiota, and disruptions in the cutaneous and gastrointestinal barriers (for example, owing to gastrointestinal perforation) promote invasive disease...
May 11, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29748331/hear-no-evil-see-no-evil-a-careful-history-with-judicious-use-of-imaging-in-detecting-brain-abscess
#17
Catherine Long, Nigel Curtis, Bridget Joan Freyne
No abstract text is available yet for this article.
May 10, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29747889/oxygen-therapy-in-the-delivery-room-what-is-the-right-dose
#18
REVIEW
Vishal Kapadia, Myra H Wyckoff
Oxygen is the most commonly used medicine used during neonatal resuscitation in the delivery room. Oxygen therapy in delivery room should be used judiciously to avoid oxygen toxicity while delivering sufficient oxygen to prevent hypoxia. Measurement of appropriate oxygenation relies on pulse oximetry, but adequate ventilation and perfusion are equally important for oxygen delivery. In this article, we review oxygenation while transitioning from fetal to neonatal life, the importance of appropriate oxygen therapy, its measurement in the delivery room, and current recommendations for oxygen therapy and its limitations...
June 2018: Clinics in Perinatology
https://www.readbyqxmd.com/read/29746348/homeless-status-postdischarge-health-care-utilization-and-readmission-after-surgery
#19
Ashley Titan, Laura Graham, Amy Rosen, Kamal Itani, Laurel A Copeland, Hillary J Mull, Edith Burns, Joshua Richman, Stefan Kertesz, Tyler Wahl, Melanie Morris, Jeffery Whittle, Gordon Telford, Mark Wilson, Mary Hawn
INTRODUCTION: Homeless Veterans are vulnerable to poor care transitions, yet little research has examined their risk of readmission following inpatient surgery. This study investigates the predictors of surgical readmission among homeless relative to housed Veteran patients. METHODS: Inpatient general, vascular, and orthopedic surgeries occurring in the Veterans Health Administration from 2008 to 2014 were identified. Administrative International Classification of Diseases, Ninth Revision, Clinical Modification codes and Veterans Health Administration clinic stops were used to identify homeless patients...
June 2018: Medical Care
https://www.readbyqxmd.com/read/29745346/orodispersible-films-a-systematic-patent-review
#20
Ashwini Deshpande, Chaitrali Gijare
BACKGROUND: In Recent years, oral film technology is aimed by the research groups. Oral film technology (OFT) has gained much attention among all the oral drug delivery systems. Fast dissolving film, fast disintegrating film and orodispersible film are some alternative words for this dosage form. Without a need of liquid for administration this dosage form dissolves in the mouth. Typically, fast dissolving film dissolves from 1 to 30 seconds. OBJECTIVE: At the root of this originality, many researchers patented their work on the aspect of orodispersible films using different drugs, polymers, excipients and employing methods of preparation...
May 8, 2018: Recent Patents on Drug Delivery & Formulation
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