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Motivational states and learning

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https://www.readbyqxmd.com/read/28922121/motion-blur-kernel-estimation-via-deep-learning
#1
Xiangyu Xu, Jinshan Pan, Yu-Jin Zhang, Ming-Hsuan Yang
The success of the state-of-the-art deblurring methods mainly depends on restoration of sharp edges in a coarse-tofine kernel estimation process. In this paper, we propose to learn a deep convolutional neural network for extracting sharp edges from blurred images. Motivated by the success of the existing filtering based deblurring methods, the proposed model consists of two stages: suppressing extraneous details and enhancing sharp edges. We show that the two-stage model simplifies the learning process and effectively restores sharp edges...
September 18, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28902472/the-mushroom-body-d1-dopamine-receptor-controls-innate-courtship-drive
#2
Junghwa Lim, Ana I Fernandez, Samantha J Hinojos, Gissel P Aranda, Jacqueline James, Chang-Soo Seong, Kyung-An Han
Mating is critical for species survival and is profoundly regulated by neuromodulators and neurohormones to accommodate internal states and external factors. To identify the underlying neuromodulatory mechanisms, we investigated the roles of dopamine receptors in various aspects of courtship behavior in Drosophila. Here we report that the D1 dopamine receptor dDA1 regulates courtship drive in naïve males. The wild-type naïve males actively courted females regardless their appearance or mating status. On the contrary, the dDA1 mutant (dumb) males exhibited substantially reduced courtship toward less appealing females including decapitated, leg-less and mated females...
September 13, 2017: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/28898959/cognitive-training-using-a-novel-memory-game-on-an-ipad-in-patients-with-amnestic-mild-cognitive-impairment-amci
#3
George Savulich, Thomas Piercy, Chris Fox, John Suckling, James B Rowe, John T O'Brien, Barbara J Sahakian
Background: Cognitive training is effective in patients with mild cognitive impairment but does not typically address the motivational deficits associated with older populations with memory difficulties. Methods: We conducted a randomized controlled trial of cognitive training using a novel memory game on an iPad in 42 patients with a diagnosis of amnestic mild cognitive impairment assigned to either the cognitive training (n=21; 8 hours of gameplay over 4 weeks) or control (n=21; clinic visits as usual) groups...
August 1, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28890049/psychological-processes-in-chronic-pain-influences-of-reward-and-fear-learning-as-key-mechanisms-behavioral-evidence-neural-circuits-and-maladaptive-changes
#4
Frauke Nees, Susanne Becker
In the understanding of chronic pain, hypotheses derived from psychological theories, together with insights from physiological assessments and brain imaging, highlight the importance of mechanistically driven approaches. Physical system changes, for example following injury, can result in alterations of psychological processes and are accompanied by changes in corticolimbic circuits, which have been shown to be essential in emotional learning and memory, as well as reward processing and related behavior. In the present review, we thus highlight the importance of motivational, reward/pain relief, and fear learning processes in the context of chronic pain and discuss the potential of a mechanistic understanding of chronic pain within a clinical perspective, for example for the development of therapeutic strategies...
September 7, 2017: Neuroscience
https://www.readbyqxmd.com/read/28887899/the-anterior-insula-bidirectionally-modulates-cost-benefit-decision-making-on-a-rodent-gambling-task
#5
M L Daniel, P J Cocker, J Lacoste, A C Mar, J L Houeto, A Belin-Rauscent, D Belin
Deficits in cost-benefit decision making, as assessed in the Iowa Gambling Task (IGT), are commonly observed in neuropsychiatric disorders such as addiction. There is considerable variation in the maximisation of rewards on such tasks, both in the general population and in rodent models, suggesting individual differences in decision making may represent a key endophenotype for vulnerability to neuropsychiatric disorders. Increasing evidence suggests that the insular cortex, which is involved in interoception and emotional processes in humans, may be a key neural locus in the control of decision making processes...
September 9, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28883804/the-influences-of-emotion-on-learning-and-memory
#6
REVIEW
Chai M Tyng, Hafeez U Amin, Mohamad N M Saad, Aamir S Malik
Emotion has a substantial influence on the cognitive processes in humans, including perception, attention, learning, memory, reasoning, and problem solving. Emotion has a particularly strong influence on attention, especially modulating the selectivity of attention as well as motivating action and behavior. This attentional and executive control is intimately linked to learning processes, as intrinsically limited attentional capacities are better focused on relevant information. Emotion also facilitates encoding and helps retrieval of information efficiently...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28882000/integrative-deep-models-for-alternative-splicing
#7
Anupama Jha, Matthew R Gazzara, Yoseph Barash
Motivation: Advancements in sequencing technologies have highlighted the role of alternative splicing (AS) in increasing transcriptome complexity. This role of AS, combined with the relation of aberrant splicing to malignant states, motivated two streams of research, experimental and computational. The first involves a myriad of techniques such as RNA-Seq and CLIP-Seq to identify splicing regulators and their putative targets. The second involves probabilistic models, also known as splicing codes, which infer regulatory mechanisms and predict splicing outcome directly from genomic sequence...
July 15, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28863855/implicit-guidance-of-attention-the-priority-state-space-framework
#8
REVIEW
Rebecca M Todd, Maria G M Manaligod
Visual selective attention is the process by which we tune ourselves to the world so that, of the millions of bits per second transmitted by the retina, the information that is most important to us reaches awareness and directs action. Recently, new areas of attention research have opened up as classic models dividing attention into top-down and bottom-up systems have been challenged. In this paper, we propose a theoretical framework, the priority state space (PSS) framework, integrating sources of salience that guide visual attention according to a nested hierarchy of goals...
August 10, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28860980/chronic-nicotine-exposure-initiated-in-adolescence-and-unpaired-to-behavioral-context-fails-to-enhance-sweetened-ethanol-seeking
#9
Aric C Madayag, Kyle S Czarnecki, Lynde M Wangler, Donita L Robinson
Nicotine use in adolescence is pervasive in the United States and, according to the Gateway Hypothesis, may lead to progression towards other addictive substances. Given the prevalence of nicotine and ethanol comorbidity, it is difficult to ascertain if nicotine is a gateway drug for ethanol. Our study investigated the relationship between adolescent exposure to nicotine and whether this exposure alters subsequent alcohol seeking behavior. We hypothesized that rats exposed to nicotine beginning in adolescence would exhibit greater alcohol seeking behavior than non-exposed siblings...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28852036/pheromones-modulate-reward-responsiveness-and-non-associative-learning-in-honey-bees
#10
David Baracchi, Jean-Marc Devaud, Patrizia d'Ettorre, Martin Giurfa
Pheromones are chemical messengers that trigger stereotyped behaviors and/or physiological processes in individuals of the same species. Recent reports suggest that pheromones can modulate behaviors not directly related to the pheromonal message itself and contribute, in this way, to behavioral plasticity. We tested this hypothesis by studying the effect of pheromones on sucrose responsiveness and habituation in honey bees. We exposed workers to three pheromone components: geraniol, which in nature is used in an appetitive context, and isopentyl acetate (IPA) and 2-heptanone (2H), which signal aversive situations...
August 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28844891/implementing-the-academy-of-nutrition-and-dietetics-benchmarks-for-nutrition-education-for-children-child-care-providers-perspectives
#11
Dipti A Dev, Virginia Carraway-Stage, Daniel J Schober, Brent A McBride, Car Mun Kok, Samantha Ramsay
BACKGROUND: National childhood obesity prevention policies recommend that child-care providers educate young children about nutrition to improve their nutrition knowledge and eating habits. Yet, the provision of nutrition education (NE) to children in child-care settings is limited. OBJECTIVE: Using the 2011 Academy of Nutrition and Dietetics benchmarks for NE in child care as a guiding framework, researchers assessed child-care providers' perspectives regarding delivery of NE through books, posters, mealtime conversations, hands-on learning, and sensory exploration of foods to young children (aged 2 to 5 years)...
August 24, 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/28802449/living-with-an-autonomous-spatiotemporal-home-heating-system-exploration-of-the-user-experiences-ux-through-a-longitudinal-technology-intervention-based-mixed-methods-approach
#12
Martin Kruusimagi, Sarah Sharples, Darren Robinson
Rising energy demands place pressure on domestic energy consumption, but savings can be delivered through home automation and engaging users with their heating and energy behaviours. The aim of this paper is to explore user experiences (UX) of living with an automated heating system regarding experiences of control, understanding of the system, emerging thermal behaviours, and interactions with the system as this area is not sufficiently researched in the existing homes setting through extended deployment. We present a longitudinal deployment of a quasi-autonomous spatiotemporal home heating system in three homes...
November 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28771992/improving-evaluation-at-two-medical-schools
#13
Sarah Schiekirka-Schwake, Katharina Dreiling, Katharina Pyka, Sven Anders, Nicole von Steinbüchel, Tobias Raupach
BACKGROUND: Student evaluations of teaching can provide useful feedback for teachers and programme coordinators alike. We have designed a novel evaluation tool assessing teacher performance and student learning outcome. This tool was implemented at two German medical schools. In this article, we report student and teacher perceptions of the novel tool, and the implementation process. METHODS: Focus group discussions as well as one-to-one interviews involving 22 teachers and 31 undergraduate medical students were conducted...
August 3, 2017: Clinical Teacher
https://www.readbyqxmd.com/read/28752234/implementing-a-tobacco-free-hospital-campus-in-ireland-lessons-learned
#14
D McArdle, Z Kabir
BACKGROUND: The Irish Health Service Executive (HSE) had set a target that all HSE facilities should implement the HSE Tobacco Free Campus (TFC) policy by 2015. AIM: The aims of this study are to examine hospital staff awareness and to assess the progress of selected HSE health care facilities towards a TFC policy. METHODS: Three health care facilities that were conveniently located were self-selected in County Cork, namely, an acute hospital, a mental health service and an older person's facility...
July 27, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28733248/pupil-dilations-induced-by-barely-conscious-reward-goal-priming
#15
Yudai Takarada, Daichi Nozaki
The topic of unconscious influences on behavior has long been explored as a way of understanding human performance and the neurobiological correlates of intention, motivation and action. Previous research using transcranial magnetic stimulation has demonstrated that barely visible priming of an action concept, when combined with reward in the form of a consciously perceived positive stimulus, can alter the state of the motor system and enhance the maximal voluntary force level. One possible explanation is that positive stimulus-induced reward signals are processed by the dopaminergic system in the basal ganglia, motivating individuals to increase the effort they invest in particular behaviors, or to recruit the resources necessary for maintaining those behaviors...
July 18, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28717716/breast-cancer-and-african-ancestry-lessons-learned-at-the-10-year-anniversary-of-the-ghana-michigan-research-partnership-and-international-breast-registry
#16
Evelyn Jiagge, Joseph Kwaku Oppong, Jessica Bensenhaver, Francis Aitpillah, Kofi Gyan, Ishmael Kyei, Ernest Osei-Bonsu, Ernest Adjei, Michael Ohene-Yeboah, Kathy Toy, Karen Eubanks Jackson, Marian Akpaloo, Dorcas Acheampong, Beatrice Antwi, Faustina Obeng Agyeman, Zainab Alhassan, Linda Ahenkorah Fondjo, Osei Owusu-Afriyie, Robert Newman Brewer, Amma Gyamfuah, Barbara Salem, Timothy Johnson, Max Wicha, Sofia Merajver, Celina Kleer, Judy Pang, Emmanuel Amankwaa-Frempong, Azadeh Stark, Francis Abantanga, Lisa Newman, Baffour Awuah
Women with African ancestry in western, sub-Saharan Africa and in the United States represent a population subset facing an increased risk of being diagnosed with biologically aggressive phenotypes of breast cancer that are negative for the estrogen receptor, the progesterone receptor, and the HER2/neu marker. These tumors are commonly referred to as triple-negative breast cancer. Disparities in breast cancer incidence and outcome related to racial or ethnic identity motivated the establishment of the International Breast Registry, on the basis of partnerships between the Komfo Anokye Teaching Hospital in Kumasi, Ghana, the University of Michigan Comprehensive Cancer Center in Ann Arbor, Michigan, and the Henry Ford Health System in Detroit, Michigan...
October 2016: Journal of Global Oncology
https://www.readbyqxmd.com/read/28715638/marcus-theory-of-ion-pairing
#17
Santanu Roy, Marcel D Baer, Christopher J Mundy, Gregory K Schenter
We present a theory for ion pair dissociation and association, motivated by the concepts of Marcus theory of electron transfer. Despite the extensive research on ion-pairing in many chemical and biological processes, much can be learned from the exploration of collective reaction coordinates. To this end, we explore two reaction coordinates, ion pair distance and coordination number. The study of the correlation between these reaction coordinates provides a new insight into the mechanism and kinetics of ion pair dissociation and association in water...
July 31, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28683032/increasing-nurse-confidence-in-patient-teaching-using-motivational-interviewing
#18
Patricia J Stoffers, Carol Hatler
This article describes a pilot study that involves nurses learning motivational interviewing techniques as a way to enhance confidence in educating patients about diabetes. The pilot study took place in the medical telemetry unit of a large teaching hospital in southwest United States. The intervention included a 2-hour session that involved didactic and role-playing components. Presurvey and postsurvey results indicated that the intervention significantly improved nurses' confidence in teaching patients (t = -7...
July 2017: Journal for Nurses in Professional Development
https://www.readbyqxmd.com/read/28665045/extraction-of-dynamic-functional-connectivity-from-brain-grey-matter-and-white-matter-for-mci-classification
#19
Xiaobo Chen, Han Zhang, Lichi Zhang, Celina Shen, Seong-Whan Lee, Dinggang Shen
Brain functional connectivity (FC) extracted from resting-state fMRI (RS-fMRI) has become a popular approach for diagnosing various neurodegenerative diseases, including Alzheimer's disease (AD) and its prodromal stage, mild cognitive impairment (MCI). Current studies mainly construct the FC networks between grey matter (GM) regions of the brain based on temporal co-variations of the blood oxygenation level-dependent (BOLD) signals, which reflects the synchronized neural activities. However, it was rarely investigated whether the FC detected within the white matter (WM) could provide useful information for diagnosis...
October 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28649770/precepting-nurse-practitioner-students-a-new-view-results-of-two-national-surveys-of-nurse-practitioner-preceptors
#20
Mary Ellen Roberts, Kathy J Wheeler, Diane O Tyler, Diane L Padden
PURPOSE: The aim of two national studies was to identify characteristics of nurse practitioners (NPs) who precept and the benefits, incentives, and barriers associated with the NP preceptor role. METHODS: Stratified randomized sampling was used to invite a representative number of NPs from each state to participate in a 2015 survey and a follow-up survey in 2016. These descriptive, exploratory studies distributed electronic questionnaires to 5000 randomly selected NPs in the 2015 survey and 40,000 NPs in the 2016 survey...
June 26, 2017: Journal of the American Association of Nurse Practitioners
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