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https://www.readbyqxmd.com/read/27901627/effects-of-pediatric-asthma-care-coordination-in-underserved-communities-on-parent-perceptions-of-care-and-asthma-management-confidence
#1
Mary R Janevic, Alan P Baptist, Tyra Bryant-Stephens, Marielena Lara, Victoria Persky, Gilberto Ramos-Valencia, Kimberly Uyeda, Rebecca Hazan, Ashley Garrity, Floyd J Malveaux
OBJECTIVE: Disparities by race and socioeconomic status persist in pediatric asthma morbidity, mortality, and treatment. Improving parent/provider communication and parents' asthma-management confidence may result in better asthma control in vulnerable populations. The Merck Childhood Asthma Network, Inc. funded an initiative to implement medical-social care coordination to improve asthma outcomes at sites in four low-income, urban communities (Los Angeles, CA; Philadelphia, PA; Chicago, IL; and San Juan, PR...
November 30, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27867307/adequate-vitamin-d-intake-but-low-serum-levels-in-pediatric-asthma-patients-a-pilot-study-alberta-children-s-hospital
#2
Sarah Howe McKenna, Tanis R Fenton, Mary Noseworthy, Mark Anselmo
Background. We assessed vitamin D intakes and serum 25(OH) vitamin D levels in pediatric asthma patients on moderate-to-high dose inhaled steroids and compared them to published findings of healthy children in our city. Methods. Parents and/or patients were interviewed to estimate the children's vitamin D intakes from foods and supplements (using an adapted validated food frequency questionnaire) and asthma duration and management. Vitamin D status: serum 25-hyroxy vitamin D (25(OH)D) was obtained from the medical records...
2016: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
https://www.readbyqxmd.com/read/27785078/anti-inflammatory-dosing-of-theophylline-in-the-treatment-of-status-asthmaticus-in-children
#3
Nemr S Eid, Adrian O'Hagan, Scott Bickel, Ronald Morton, Sarah Jacobson, John A Myers
BACKGROUND: Low-dose theophylline has been recognized for its ability to restore histone deacetylase-2 activity which leads to improved steroid responsiveness and thus improved clinical outcome. We retrospectively evaluated the effect of low-dose theophylline therapy in pediatric patients hospitalized for an acute asthma exacerbation as a proof of concept study. METHODS: We compared patients who received low-dose theophylline (5-7 mg/kg/day) in addition to current standard of care to patients who were treated with current standard of care alone...
2016: Journal of Asthma and Allergy
https://www.readbyqxmd.com/read/27739908/asthma-allergy-and-obesity-examining-the-relationship-among-nevada-children
#4
Jennifer A Lucas, Sheniz Moonie, Kimberly Olsen-Wilson, Mary Beth Hogan
OBJECTIVE: The majority of pediatric asthma is atopic, but whether pediatric obese asthma is atopic is indeterminate in the literature. In Nevada, children become sensitized to aeroallergens, a risk factor for asthma, at young ages. Additionally, Nevada children have high rates of obesity. Our objective is to determine whether elevated body mass index (BMI) is associated with asthma severity, allergen sensitization, and polysensitization. METHODS: Medical records from a pediatric allergy clinic provided BMI percentile, physician-diagnosed asthma severity, skin prick test data, and sociodemographics such as age, race, sex, and insurance status from asthmatic patients...
October 14, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27695350/study-of-the-correlations-between-fractional-exhaled-nitric-oxide-in-exhaled-breath-and-atopic-status-blood-eosinophils-fcer2-mutation-and-asthma-control-in-vietnamese-children
#5
Hanh Nguyen-Thi-Bich, Huong Duong-Thi-Ly, Vu Thi Thom, Nhung Pham-Thi-Hong, Long Doan Dinh, Huong Le-Thi-Minh, Timothy John Craig, Sy Duong-Quy
INTRODUCTION: Fractional exhaled nitric oxide (FENO) is a biomarker of airway inflammation in asthma. The measurement of FENO is utilized to assist in the diagnosis and treatment of children with asthma, especially for those treated with inhaled corticosteroids. OBJECTIVES: The aims of this study were to evaluate the correlations between FENO and atopic status, blood eosinophil levels, FCER2 mutation, and asthma control in Vietnamese children. SUBJECTS AND METHODS: This was a prospective and descriptive study approved by the local Ethical Board...
2016: Journal of Asthma and Allergy
https://www.readbyqxmd.com/read/27664979/determinants-of-longitudinal-health-related-quality-of-life-change-in-children-with-asthma-from-low-income-families-a-report-from-the-promis-%C3%A2-pediatric-asthma-study
#6
Z Li, W L Leite, L A Thompson, H E Gross, E A Shenkman, B B Reeve, D A DeWalt, I-C Huang
BACKGROUND: How the longitudinal asthma control status and other socio-demographic factors influence the changes of health-related quality of life (HRQOL) among asthmatic children, especially from low-income families, has not been fully investigated. OBJECTIVES: This study aimed to describe the trajectories of asthma-specific HRQOL over 15 months and examine the effect of asthma control status on HRQOL by taking socio-demographic factors into consideration. METHODS: A total of 229 dyads of asthmatic children and their parents enroled in public insurance programs were recruited for assessing asthma control status and HRQOL over four time points of assessment...
September 24, 2016: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27633404/gene-environment-interaction-in-the-intergenerational-transmission-of-asthma
#7
Owen Thompson
Researchers have found strong linkages between parent and child health, but the mechanisms underlying intergenerational health transmission are not well understood. This paper investigates how the importance of genetic health transmission mechanisms varies by environmental conditions in the case of pediatric asthma, the single most common chronic health condition among American children. Using a sample that includes approximately 2000 adoptees and a large number of similar biological families, I find that the relative importance of genetic transmission differs strongly by socioeconomic status (SES)...
September 15, 2016: Health Economics
https://www.readbyqxmd.com/read/27611488/identification-of-four-novel-loci-in-asthma-in-european-and-african-american-populations
#8
Berta Almoguera, Lyam Vazquez, Frank Mentch, John Connolly, Jennifer A Pacheco, Agnes S Sundaresan, Peggy L Peissig, James G Linneman, Catherine A McCarty, David Crosslin, David S Carrell, Todd Lingren, Bahram Namjou-Khales, John B Harley, Eric Larson, Gail P Jarvik, Murray Brilliant, Marc S Williams, Iftikhar J Kullo, Erik B Hysinger, Patrick M A Sleiman, Hakon Hakonarson
RATIONALE: Despite significant advances in our knowledge of the genetic architecture of asthma, specific contributors to the variability in the burden between populations remain uncovered. OBJECTIVE: To identify additional genetic susceptibility factors of asthma in European American and African American populations. METHODS: A phenotyping algorithm mining Electronic Medical Records was developed and validated to recruit cases with asthma and controls from the eMERGE (electronic Medical Records and Genomics) network...
September 9, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27554823/mendelian-randomization-analysis-demonstrates-that-low-vitamin-d-is-unlikely-causative-for-pediatric-asthma
#9
Erik B Hysinger, Jeffrey D Roizen, Frank D Mentch, Lyam Vazquez, John J Connolly, Jonathan P Bradfield, Berta Almoguera, Patrick M Sleiman, Julian L Allen, Michael A Levine, Hakon Hakonarson
We confirmed associations between 25(OH)D and asthma in our cross-sectional cohort; however, genetically predicted vitamin D status was not associated with asthma. These results suggest that vitamin D is unlikely causative for pediatric asthma.
August 20, 2016: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27551858/estimating-pediatric-asthma-prevalence-in-rural-senegal-a-cross-sectional-survey
#10
Laura G Hooper, Yakou Dieye, Assane Ndiaye, Aldiouma Diallo, Vincent S Fan, Kathleen M Neuzil, Justin R Ortiz
RATIONALE: In Senegal, the prevalence of childhood asthma and utilization of appropriate asthma therapies is unknown. METHODOLOGY: We used the International Study of Asthma and Allergies in Childhood (ISAAC) survey instrument to assess childhood respiratory health in rural Senegal. We interviewed the caregivers of children aged 5 through 8 years of age in the four largest Niakhar villages in August 2012. RESULTS: We interviewed 1,103 primary caregivers for 1,513 children, representing 91% of all age-eligible children in the study area...
August 23, 2016: Pediatric Pulmonology
https://www.readbyqxmd.com/read/27485682/path-to-health-asthma-study-a-survey-of-pediatric-asthma-in-an-urban-community
#11
Norma Alicea-Alvarez, Carlo Foppiano Palacios, Melanie Ortiz, Diana Huang, Kathleen Reeves
OBJECTIVE: Minority children with asthma who live in low-income urban communities bear a disproportionate burden of the disease. This study explores the perceived health care needs related to asthma care, identifies asthma triggers, potential barriers to care, and assesses the need for additional community resources. METHODS: We conducted a cross-sectional survey of Hispanic and African American adults (n = 53) who take care of a child with asthma and live in an urban community of North Philadelphia...
August 2, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27485318/influence-of-asthma-status-on-sleep-variability-in-overweight-obese-youth
#12
Kendra N Krietsch, Casey Lawless, David A Fedele, Christina S McCrae, David M Janicke
OBJECTIVE: Pediatric asthma and overweight/obesity (OV/OB) frequently co-occur and youth with both conditions exhibit poor sleep/bedtime habits. This study assessed differences in week-to-weekend bedtime/wake time variability among OV/OB youth with/without comorbid asthma, and tested whether variability predicted weekday sleep. METHODS: OV/OB youth (n = 142; 28% comorbid asthma; 7-12 years) wore an Accelerometer for 5 days (2 weekend days), providing estimates of week-to-weekend bedtime/wake-time variability, weekday Total Sleep Time (TST), weekday time in bed (TIB), and weekday wake after sleep onset (WASO)...
August 2, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27428241/general-anesthesia-exposure-in-early-life-reduces-the-risk-of-allergic-diseases-a-nationwide-population-based-cohort-study
#13
Ho-Chang Kuo, Ya-Ling Yang, Shu-Chen Ho, Mindy Ming-Huey Guo, Jyun-Hong Jiang, Ying-Hsien Huang
General anesthesia (GA) has been used for second line treatment strategy for status asthmaticus in pediatric patients. The association between GA in children and risk of followed-up allergic diseases is unclear. This study aims to assess the risk of allergic diseases after GA in children.We did a nationwide retrospective cohort study by analyzing data from the National Health Insurance Research Database (NHIRD) in Taiwan. The subsequent risks for allergic diseases, including asthma (ICD-9: 493.X), allergic rhinitis (AR; ICD-9 CM code 477...
July 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27423071/evaluation-of-therapeutics-management-patterns-and-glycemic-control-of-pediatric-type-1-diabetes-mellitus-patients-in-turkey-a-nationwide-cross-sectional-study
#14
Şükrü Hatun, Hüseyin Demirbilek, Şükran Darcan, Ayşegül Yüksel, Cigdem Binay, Damla Gökşen Şimşek, Cengiz Kara, Ergun Çetinkaya, Tolga Ünüvar, Ahmet Uçaktürk, Filiz Tütüncüler, Yaşar Cesur, Ruveyde Bundak, Halil Sağlam, Enver Şimşek, Abdullah Bereket
AIMS: To evaluate the management strategies, glycemic control and complications of pediatric type 1 diabetes mellitus (T1DM) patients in Turkey. METHODS: Study included 498 patients with T1DM between the ages 1-18. Data provided from patients' hospital files were recorded on standard case report forms by applicant clinicians within the 3months of data collection period between October 2012 and July 2013. RESULTS: Mean age of patients was 11...
September 2016: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/27385812/practice-patterns-in-medicaid-and-non-medicaid-asthma-admissions
#15
Jeffrey H Silber, Paul R Rosenbaum, Wei Wang, Shawna Calhoun, James P Guevara, Joseph J Zorc, Orit Even-Shoshan
BACKGROUND AND OBJECTIVES: With American children experiencing increased Medicaid coverage, it has become especially important to determine if practice patterns differ between Medicaid and non-Medicaid patients. Auditing such potential differences must carefully compare like patients to avoid falsely identifying suspicious practice patterns. We asked if we could observe differences in practice patterns between Medicaid and non-Medicaid patients admitted for asthma inside major children's hospitals...
August 2016: Pediatrics
https://www.readbyqxmd.com/read/27328326/using-video-from-mobile-phones-to-improve-pediatric-phone-triage-in-an-underserved-population
#16
Brandi Freeman, Stephanie Mayne, A Russell Localio, Anthony Luberti, Joseph J Zorc, Alexander G Fiks
BACKGROUND: Video-capable mobile phones are widely available, but few studies have evaluated their use in telephone triage for pediatric patients. We assessed the feasibility, acceptability, and utility of videos sent via mobile phones to enhance pediatric telephone triage for an underserved population with asthma. MATERIALS AND METHODS: We recruited children who presented to an urban pediatric emergency department with an asthma exacerbation along with their parent/guardian...
June 21, 2016: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/27323141/meta-analysis-of-the-il-10-promoter-polymorphisms-and-pediatric-asthma-susceptibility
#17
Z Y Huang, B J Cheng, Y Wan, C Zhou
The results of previous epidemiological studies exploring the relationship between interleukin-10 (IL-10) promoter polymorphisms and susceptibility to pediatric asthma are not consistent. Therefore, we have performed a systematic review and meta-analysis to provide a more convincing conclusion. Odds ratios (OR) with their 95% confidence intervals (CIs) were used to evaluate the strength of association between the IL-10 promoter polymorphisms and susceptibility to pediatric asthma. Publication bias was examined by Begg's funnel plots and the Egger test...
2016: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/27318225/longitudinal-associations-among-asthma-control-sleep-problems-and-health-related-quality-of-life-in-children-with-asthma-a-report-from-the-promis-%C3%A2-pediatric-asthma-study
#18
Zheng Li, Lindsay A Thompson, Heather E Gross, Elizabeth A Shenkman, Bryce B Reeve, Darren A DeWalt, I-Chan Huang
OBJECTIVES: Few studies have investigated the complex relationship among asthma control, sleep problems, and health-related quality of life (HRQOL) among children with asthma. This study aimed to test the longitudinal effect of asthma control status on asthma-specific HRQOL through the mechanism of nighttime sleep quality and daytime sleepiness. METHODS: The Patient-Reported Outcomes Measurement Information System (PROMIS(®)) Pediatric Asthma Study included 229 dyads of asthmatic children and their parents with two years of follow-up for assessing the change in asthma control, sleep problems, and asthma-specific HRQOL...
April 2016: Sleep Medicine
https://www.readbyqxmd.com/read/27282717/health-disparities-in-pediatric-asthma-comprehensive-tertiary-care-center-experience
#19
Laurens Holmes, Fanta Kalle, Laura Grinstead, Maritza Jimenez, Meghan Murphy, Pat Oceanic, Diane Fitzgerald, Kirk Dabney
LOCATION: Study conducted at Nemours /Alfred I. duPont Hospital for Children, Wilmington, DE 19803 BACKGROUND: Although the treatment and management of asthma hasimproved over time, incidence and prevalence among children continues to rise in the United States. Asthma prevalence, health services utilization, and mortality rate demonstrate remarkable disparities. The underlying causes of these disparities are not fully understood. We aimed to examine racial/ethnic variances in pediatric asthma prevalence/admission...
March 2015: Journal of the National Medical Association
https://www.readbyqxmd.com/read/27227975/a-screening-tool-for-assessing-alcohol-use-risk-among-medically-vulnerable-youth
#20
Sharon Levy, Fatma Dedeoglu, Jonathan M Gaffin, Katharine C Garvey, Elizabeth Harstad, Andrew MacGinnitie, Paul A Rufo, Qian Huang, Rosemary E Ziemnik, Lauren E Wisk, Elissa R Weitzman
BACKGROUND: In an effort to reduce barriers to screening for alcohol use in pediatric primary care, the National Institute on Alcoholism and Alcohol Abuse (NIAAA) developed a two-question Youth Alcohol Screening Tool derived from population-based survey data. It is unknown whether this screening tool, designed for use with general populations, accurately identifies risk among youth with chronic medical conditions (YCMC). This growing population, which comprises nearly one in four youth in the US, faces a unique constellation of drinking-related risks...
2016: PloS One
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