keyword
MENU ▼
Read by QxMD icon Read
search

Spontaneous Abortion

keyword
https://www.readbyqxmd.com/read/28533329/pregnancy-outcome-after-first-trimester-use-of-methyldopa-a-prospective-cohort-study
#1
Maria Hoeltzenbein, Evelin Beck, Anne-Katrin Fietz, Juliane Wernicke, Sandra Zinke, Angela Kayser, Stephanie Padberg, Corinna Weber-Schoendorfer, Reinhard Meister, Christof Schaefer
Published experience on first trimester exposure to methyldopa is still limited, although it is recommended as first-line treatment for hypertensive disorders in pregnancy in most countries. The primary aim of this prospective observational cohort study was to analyze the rate of major birth defects and spontaneous abortions in women with methyldopa therapy for chronic hypertension. Outcomes of 261 pregnancies with first trimester exposure to methyldopa and 526 comparison pregnancies without chronic hypertension reported to the German Embryotox pharmacovigilance institute were evaluated...
May 22, 2017: Hypertension
https://www.readbyqxmd.com/read/28532196/fetal-and-neonatal-involvement-in-maternal-rheumatologic-disease
#2
Shigeo Iijima
A pregnancy complicated with rheumatologic diseases can have various influences on the fetus and/or neonate. Maternal systemic lupus erythematosus (SLE) may cause preterm and/or small for gestational age (SGA) delivery and neonatal lupus (NL). Some neonates with NL have congenital heart block (CHB) with increased morbidity and mortality, even requiring pacemakers. Antiphospholipid syndrome may occur with SLE and affect fetal and/or neonatal outcomes. Pregnancy involving primary Sjögren syndrome (pSS) tends to result in preterm delivery and low birthweight infants...
May 22, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28531169/expression-of-liver-receptor-homolog-1-lrh-1-in-villi-and-decidua-of-patients-with-unexplained-recurrent-spontaneous-abortion
#3
Zhiyan Xu, Xiangqing Hou, Hongtao Lv, Binghui Sun, Yingying Cui, Ling Liu, Fengnian Rong
BACKGROUND In view of the important function of nuclear receptor liver receptor homolog 1 (LRH 1) in various biological processes and the physiological changes accompanying unexplained recurrent spontaneous abortion (USRA), our study was carried out to investigate the potential roles of LRH-1 in USRA. MATERIAL AND METHODS Thirty patients with URSA at early the early state of pregnancy were selected, and 30 patients with normal early pregnancy were also selected from Aug 2015 to Sep 2016 as a control group. The expression of LRH-1 protein in decidua and villi were detected by immunohistochemistry and Western blot analysis, and the expression of LRH-1 mRNA was detected by RT-PCR...
May 22, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28529751/comparison-of-lifestyle-hormonal-and-medical-factors-in-women-with-sporadic-and-lynch-syndrome-associated-endometrial-cancer-a-retrospective-case-case-study
#4
Mari H Aaltonen, Synnöve Staff, Jukka-Pekka Mecklin, Kirsi Pylvänäinen, Johanna U Mäenpää
Data available on lifestyle-associated hormonal and medical factors among endometrial cancer (EC)-affected women who carry the Lynch Syndrome (LS) mutation is limited. The aim of the present retrospective case study was to compare the reproductive and medical history, as well as lifestyle-associated factors, among patients with LS and sporadic EC. The study population consisted of 50 verified germline mismatch repair (MMR) gene mutation carriers diagnosed with EC, and 110 sporadic EC patients. Data were collected using postal questionnaires...
May 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28525542/semiparametric-model-and-inference-for-spontaneous-abortion-data-with-a-cured-proportion-and-biased-sampling
#5
Jin Piao, Jing Ning, Christina D Chambers, Ronghui Xu
Evaluating and understanding the risk and safety of using medications for autoimmune disease in a woman during her pregnancy will help both clinicians and pregnant women to make better treatment decisions. However, utilizing spontaneous abortion (SAB) data collected in observational studies of pregnancy to derive valid inference poses two major challenges. First, the data from the observational cohort are not random samples of the target population due to the sampling mechanism. Pregnant women with early SAB are more likely to be excluded from the cohort, and there may be substantial differences between the observed SAB time and those in the target population...
May 18, 2017: Biostatistics
https://www.readbyqxmd.com/read/28516786/association-of-angiogenic-cytokines-vegf-a-and-vegf-c-and-clinical-characteristic-in-women-with-unexplained-recurrent-miscarriage
#6
A Bagheri, P Kumar, A Kamath, P Rao
INTRODUCTION: Recurrent miscarriage (RM) defined as 2 or more spontaneous miscarriage before 20 weeks of gestation, affects at least 1 % of couples trying to conceive. In over 50 % of cases, the cause of the loss of pregnancy remains unexplained. Reduced expression of Angiogenic factors such as: vascular endothelial growth factor (VEGF-A) and VEGF-C has been linked with spontaneous miscarriage, likely due to defective foetal and placental angiogenesis. AIMS AND OBJECTIVES: To investigate the relationships between serum level of VEGF-A and VEGF-C with clinical characteristic in women with URM and compare to pregnant and healthy women...
2017: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/28515588/placental-mesenchymal-dysplasia-what-every-radiologist-needs-to-know
#7
Disha Mittal, Rama Anand, Neha Sisodia, Smita Singh, Ratna Biswas
Placental mesenchymal dysplasia (PMD) is an uncommon vascular anomaly of the placenta characterized by placentomegaly with multicystic placental lesion on ultrasonography and mesenchymal stem villous hyperplasia on histopathology. Placental mesenchymal dysplasia should be considered in the differential diagnosis of cases of multicystic placental lesion such as molar pregnancy, chorioangioma, subchorionic hematoma, and spontaneous abortion with hydropic placental changes. However, lack of high-velocity signals inside the lesion and a normal karyotype favor a diagnosis of PMD...
January 2017: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/28511456/acute-rubella-virus-infection-among-women-with-spontaneous-abortion-in-mwanza-city-tanzania
#8
Lukombodzo Lulandala, Mariam M Mirambo, Dismas Matovelo, Balthazar Gumodoka, Stephen E Mshana
INTRODUCTION: Acute rubella virus infection in early pregnancy has been associated with poor pregnancy outcome ranging from spontaneous abortion, stillbirth and multiple birth defects known as Congenital Rubella Syndrome (CRS). Despite its importance the prevalence of acute rubella virus infections is not known among women with spontaneous abortion in most centres in developing countries. AIM: The present study was aimed to determine the seroprevalence of acute rubella infection among women with spontaneous abortion in Mwanza city...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28502197/effect-of-maternal-age-on-spontaneous-abortion-during-the-first-trimester-in-northeast-china
#9
Rulin Dai, Linlin Li, Haibo Zhu, Dongfeng Geng, Shu Deng, Ruizhi Liu
OBJECTIVE: We aimed to determine the relationship between fetal chromosomal abnormalities and maternal age among spontaneous first trimester abortions in women in Northeast China. METHODS: We evaluated 497 chorionic villi samples from patients with a history of spontaneous abortion during the first trimester. We divided the samples into five groups according to maternal age: <25, 25-29, 30-34, 35-39, and ≥40 years. We identified chromosomal abnormalities by fluorescence in situ hybridization...
May 14, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28500450/genetic-variation-in-matrix-metalloproteinase-mmp2-and-mmp9-as-a-risk-factor-for-idiopathic-recurrent-spontaneous-abortions-in-an-indian-population
#10
Deepika Ramu, Vettriselvi Venkatesan, Solomon Franklin Durairaj Paul, Teena Koshy
PURPOSE: Matrix metalloproteinases, MMP2 and MMP9, are found to have an important role during ovulation and pregnancy because of their capacity to degrade components of the extracellular matrix (ECM) thereby facilitating cell migration and angiogenesis. In this respect, the aim of the present study was to evaluate the association of the promoter polymorphisms -1306 C > T and -1562 C/T in MMP2 and MMP9 respectively with couples diagnosed with idiopathic recurrent spontaneous abortions (IRSA)...
May 12, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28496938/brugada-syndrome-risk-stratification-and-management
#11
REVIEW
Yoshifusa Aizawa
The Brugada syndrome (BrS) is an arrhythmogenic disease associated with an increased risk of ventricular fibrillation and sudden cardiac death. The risk stratification and management of BrS patients, particularly of asymptomatic ones, still remains challenging. A previous history of aborted sudden cardiac death or arrhythmic syncope in the presence of spontaneous type 1 ECG pattern of BrS phenotype appear to be the most reliable predictors of future arrhythmic events. Several other ECG parameters have been proposed for risk stratification...
October 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/28491217/-guillain-barr%C3%A3-syndrome-and-diabetic-acido-ketotic-decompensation-during-pregnancy-a-case-report-and-review-of-the-literature
#12
Lilia Affes, Mouna Elleuch, Fatma Mnif, Faten Hadj Kacem, Dhouha Ben Salah, Mouna Mnif, Nadia Charfi, Nabila Rekik, Mohamed Abid
A 27-year-old pregnant woman was admitted to the resuscitation department with severe spontaneous acute ketoacidosis as early symptom of type 1 diabetes. The patient underwent resuscitation and insulin treatment with good clinical and biological evolution. On day 4, the patient had polyradiculoneuritis characterised by acute onset. Additional emergency examinations were negative. Lumbar cytopunction showed albuminocytologic dissociation. Electromyogram confirmed the diagnosis of Guillain Barré syndrome (GBS)...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28487272/analysis-of-genetic-characteristics-and-reproductive-risks-of-balanced-complex-chromosome-rearrangement-carriers-in-china
#13
Liao Yaping, Wang Chunjing, Liang Meng, Hu Xiaomei, Wu Qi
To examine the type, characteristics and meiotic behavior of balanced complex chromosome rearrangements (CCRs) and their relationship with reproductive abnormalities in Chinese people, karyotype analyses were performed in 1063 couples with reproductive abnormalities using G-banding technology. Additional data were retrieved from a Chinese database and analyzed statistically with the karyotype and clinic data of CCRs. Two CCR carriers were found among the 1063 couples, and in all a total of 124 CCR carriers with the complete information were identified in the karyotype analysis and the database search...
May 20, 2017: Yi Chuan, Hereditas
https://www.readbyqxmd.com/read/28484742/serum-cytokine-levels-are-related-to-nesfatin-1-nucb2-expression-in-the-implantation-sites-of-spontaneous-abortion-model-of-cba-j-%C3%A3-dba-2-mice
#14
Yiwa Chung, Heejeong Kim, Sojeong Seon, Hyunwon Yang
The process of spontaneous abortion involves a complex mechanism with various cytokines, growth factors, and hormones during the pregnancy. However, the mechanism underlying spontaneous abortion by pro- and anti-inflammatory cytokines in the serum during the pregnancy is not fully understood. Therefore, the purpose of this study was to examine the relationship between the serum levels of pro- and anti-inflammatory cytokines and spontaneous abortion using the CBA/j × DBA/2 mouse model. Serum levels of pro-inflammatory cytokines, such as IFN-γ, IL-1α and TNF-α were not increased in abortion model mice, but anti-inflammatory cytokines, such as IL-4, IL-13 and IL-1ra were decreased compared to normal pregnant mice...
March 2017: Balsaeng'gwa Saengsig
https://www.readbyqxmd.com/read/28483501/fertility-outcomes-after-extended-searches-for-ejaculated-spermatozoa-in-men-with-virtual-azoospermia
#15
Netanella Miller, Tal Biron-Shental, Yael Pasternak, Michael Belenky, Shai Shefi, Pavel Itsykson, Arie Berkovitz
OBJECTIVE: To assess the fertility outcomes of extended searches for ejaculated spermatozoa in men with virtual azoospermia. DESIGN: A retrospective cohort of 242 couples whose male partner suffered from nonobstructive azoospermia and who were treated with the use of intracytoplasmic sperm injection (ICSI). SETTING: Not applicable. PATIENT(S): One hundred forty patients were referred to an extended search in the ejaculate and 102 patients were referred to microsurgical testicular sperm extraction (microTESE)...
May 5, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28480843/prognostic-risk-of-obstetric-and-perinatal-complications-in-pregnant-women-with-thyroid-dysfunction
#16
N Morchiladze, B Tkeshelashvili, T Gagua, D Gagua
Maternal thyroid pathology takes important role in obstetric and peri-neonatal morbidity structure. Despite of the number of studies conducted in the field of thyroid disorders of pregnant females, the definition of influence of thyroid gland dysfunction on maternal and neonatal health still remains actual. The mentioned topics draw specific interest in the aspect of prognosticaiton of complications and unfavorable outcome. Aim of the study - to define the specificities of gestation period and determine the prognostic risk of obstetric and perinatal complications in pregnant females with thyroid pathology...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28474701/-cholelithiasis-during-pregnancy-and-postpartum-prevalence-presentation-and-consequences-in-a-referral-hospital-in-baja-california-sur
#17
Andrea Socorro Álvarez-Villaseñor, Héctor Luis Mascareño-Franco, José Juan Agundez-Meza, Francisco Cardoza-Macías, Clotilde Fuentes-Orozco, Jorge Rendón-Félix, Mariana Chávez-Tostado, Leire Irusteta-Jiménez, Jesús García-Rentería, Alejandro González-Ojedaz
INTRODUCTION: Pregnancy and the postpartum period are risk factors for developing biliary sludge, gallstones, and any of their complications. OBJECTIVE: To determine the prevalence, presentation, and consequences of cholestasis during pregnancy and postpartum in a referral hospital of Baja California Sur. MATERIAL AND METHODS: This was a retrospective, observational study that enrolled pregnant or postpartum patients diagnosed with gallstones with any presentation...
March 2017: Gaceta Médica de México
https://www.readbyqxmd.com/read/28472791/microrna-873-is-a-potential-serum-biomarker-for-the-detection-of-ectopic-pregnancy
#18
Qi Lu, Qi Yan, Fengying Xu, Yuhong Li, Wenxia Zhao, Chunzhu Wu, Yudong Wang, Xiao Lang
BACKGROUND: Ectopic pregnancy (EP) refers to the implantation of the zygote outside the uterine cavity. In clinical practice, the diagnosis of EP relies on a combination of ultrasound findings and serum human chorionic gonadotrophin (hCG) measurements. However, the need for serial hCG measurements increases the risk of tubal rupture and death, underscoring the need to identify biomarkers for the early detection of EP. METHODS: The serum concentrations of 21 microRNAs (miRNAs) associated with pregnancy or with known placental expression, as well as serum hCG and progesterone levels were analyzed 36 patients with viable intrauterine pregnancy (VIP), 30 patients with spontaneous abortion (SA), and 34 patients with EP using specific assay kits and reverse transcription PCR...
May 4, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28472773/the-correlation-of-sperm-morphology-with-unexplained-recurrent-spontaneous-abortion-a-systematic-review-and-meta-analysis
#19
REVIEW
Xiaodan Cao, Yun Cui, Xiaoxia Zhang, Jiangtao Lou, Jun Zhou, Renxiong Wei
Sperm morphology displays a potential impact on sperm function and may ultimately impact reproductive function. Current studies have investigated the correlation between sperm morphology with unexplained recurrent spontaneous abortion (RSA) but have shown inconsistent results. Hence, we systematically searched MEDLINE, EMBASE, CNKI databases, as well as the Cochrane Library for studies that examined the association between sperm morphology and unexplained RSA. Fifteen studies were identified, including 883 cases and 530 controls...
April 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/28471964/prenatal-perinatal-and-postnatal-factors-associated-with-autism-a-meta-analysis
#20
Chengzhong Wang, Hua Geng, Weidong Liu, Guiqin Zhang
BACKGROUND: The aim of this meta-analysis was to investigate the prenatal, perinatal, and postnatal risk factors for children autism. METHODS: PubMed, Embase, Web of Science were used to search for studies that examined the prenatal, perinatal, and postnatal risk factors for children autism. A fixed-effects model or random-effects model was used to pool the overall effect estimates. RESULTS: Data from 37,634 autistic children and 12,081,416 nonautistic children enrolled in 17 studies were collated...
May 2017: Medicine (Baltimore)
keyword
keyword
107011
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"