keyword
MENU ▼
Read by QxMD icon Read
search

Spontaneous Abortion

keyword
https://www.readbyqxmd.com/read/29772490/effects-of-multiple-inherited-and-acquired-thrombophilia-on-outcomes-of-in-vitro-fertilization
#1
Marcello Di Nisio, Adalisa Ponzano, Gianmario Tiboni, Maria Domenica Guglielmi, Anne Wilhelmina Saskia Rutjes, Ettore Porreca
INTRODUCTION: The effects of multiple inherited and acquired thrombophilic defects on the outcome of in-vitro fertilization (IVF) remain unexplored. The aim of this study was to evaluate the association between multiple thrombophilia and clinical outcomes in a large prospective cohort of women undergoing IVF. MATERIALS AND METHODS: Consecutive women scheduled for IVF were eligible. The primary study outcome was live birth. Secondary outcomes included spontaneous abortion, clinical pregnancy, and symptomatic venous thromboembolism...
May 9, 2018: Thrombosis Research
https://www.readbyqxmd.com/read/29768442/genetic-variation-in-the-clock-gene-is-associated-with-idiopathic-recurrent-spontaneous-abortion
#2
Alenka Hodžić, Polona Lavtar, Momčilo Ristanović, Ivana Novaković, Jelena Dotlić, Borut Peterlin
Physiological studies in animals and human support an important role of circadian system in reproduction. The aim of this study was to investigate the potential association of CLOCK gene polymorphisms with idiopathic recurrent spontaneous abortion (IRSA). We performed a case-control study. The study group consisted of 268 women with a history of three or more idiopathic recurrent spontaneous abortions and 284 women with at least two live births and no history of pathologic pregnancies all from Slovenia and Serbia...
2018: PloS One
https://www.readbyqxmd.com/read/29763992/development-of-an-algorithm-to-identify-pregnancy-episodes-and-related-outcomes-in-health-care-claims-databases-an-application-to-antiepileptic-drug-use-in-4-9-million-pregnant-women-in-france
#3
Pierre-Olivier Blotière, Alain Weill, Marie Dalichampt, Cécile Billionnet, Myriam Mezzarobba, Fanny Raguideau, Rosemary Dray-Spira, Mahmoud Zureik, Joël Coste, François Alla
PURPOSE: Access to claims databases provides an opportunity to study medication use and safety during pregnancy. We developed an algorithm to identify pregnancy episodes in the French health care databases and applied it to study antiepileptic drug (AED) use during pregnancy between 2007 and 2014. METHODS: The algorithm searched the French health care databases for discharge diagnoses and medical procedures indicative of completion of a pregnancy. To differentiate claims associated with separate pregnancies, an interval of at least 28 weeks was required between 2 consecutive pregnancies resulting in a birth and 6 weeks for terminations of pregnancy...
May 15, 2018: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/29763655/no-evidence-of-adverse-pregnancy-outcome-after-exposure-to-ibuprofen-in-the-1st-trimester-evaluation-of-the-national-embryotox-cohort
#4
Katarina Dathe, Anne-Katrin Fietz, Lucas William Pritchard, Stephanie Padberg, Stefanie Hultzsch, Katja Meixner, Reinhard Meister, Christof Schaefer
Ibuprofen is an analgesic frequently used in the 1st and 2nd trimester of pregnancy. Most relevant studies deal with NSAID as a group and do not specifically focus on ibuprofen. In this study, 1117 women exposed to ibuprofen in the 1st trimester were compared to 2229 non-exposed women. Data were retrieved from the German Embryotox database. No significantly increased risk of major birth defects (4.8% vs. 4.1%; OR adjusted 1.11, 95% CI 0.75-1.64) or a distinct pattern of birth defects were found. The cumulative incidences of spontaneous abortions were similar across cohorts (15...
May 12, 2018: Reproductive Toxicology
https://www.readbyqxmd.com/read/29762820/relation-between-mycoplasma-infection-and-recurrent-spontaneous-abortion
#5
C-J Cao, Y-F Wang, D-M Fang, Y Hu
OBJECTIVE: This study explores the possible relation between cervical infections with Ureaplasma urealyticum (UU) and Mycoplasma hominis (MH) and the occurrence of recurrent spontaneous abortion (RSA). PATIENTS AND METHODS: 132 patients with RSA (observation group) and 96 normal pregnancy volunteers undergoing planned abortions (control group) were selected successively and enrolled in the investigation. Cervical secretion samples were obtained for each subject...
April 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29761670/arrhythmic-events-in-brugada-syndrome-a-nationwide-israeli-survey-of-the-clinical-characteristics-treatment-and-long-term-follow-up-israbru-vf
#6
Eran Leshem, Michael Rahkovich, Anna Mazo, Mahmoud Suleiman, Miri Blich, Avishag Laish-Farkash, Yuval Konstantino, Rami Fogelman, Boris Strasberg, Michael Geist, Israel Chetboun, Moshe Swissa, Michael Ilan, Aharon Glick, Yoav Michowitz, Raphael Rosso, Michael Glikson, Bernard Belhassen
BACKGROUND: Limited information exists about detailed clinical characteristics and management of the small subset of Brugada syndrome (BrS) patients who had an arrhythmic event (AE). OBJECTIVES: To conduct the first nationwide survey focused on BrS patients with documented AE. METHODS: Israeli electrophysiology units participated if they had treated BrS patients who had cardiac arrest (CA) (lethal/aborted; group 1) or experienced appropriate therapy for tachyarrhythmias after prophylactic implantable cardioverter defibrillator (ICD) implantation (group 2)...
May 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29757875/surgery-and-platinum-etoposide-based-chemotherapy-for-the-treatment-of-epithelioid-trophoblastic-tumor
#7
Janelle Sobecki-Rausch, Abigail Winder, Kruti P Maniar, Anna V Hoekstra, Emily Berry, Karen Novak, John R Lurain
OBJECTIVE: Epithelioid trophoblastic tumor (ETT) is a rare variant of gestational trophoblastic neoplasia that develops from chorionic-type intermediate trophoblast, simulates carcinoma, presents years after a pregnancy event, is associated with low or normal human chorionic gonadotropin levels, and is relatively resistant to chemotherapy. Our aim was to identify the role of surgery in combination with platinum/etoposide-based chemotherapy in the management of both localized and metastatic ETT...
May 4, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29745913/benefits-of-early-screening-and-proper-treatment-in-patient-with-significant-risk-factors-for-gestational-diabetes-mellitus-case-report
#8
V Limani
Gestational diabetes mellitus (GDM) occurs in 2-9% of all pregnancies. Evidence suggests that the use of insulin in treating hyperglycemia in GDM patients reduces the risk of perinatal morbidity. Pregnancy is an exciting time in a woman's life. However, once patient is diagnosed with GDM, she will be managed more intensively. GDM is managed using diet and exercise but one in six women with GDM requires insulin. A 35-year-old woman at the 14th gestational week of her tenth pregnancy was seen for routine prenatal care...
April 2018: Georgian Medical News
https://www.readbyqxmd.com/read/29742294/risk-factors-for-self-reported-postpartum-hemorrhage-in-ga-east-ghana
#9
Viviane Valdes, Philip B Adongo, Adanna U Nwameme, Philip T N Tabong, Michelle Fernandes
OBJECTIVE: To document the prevalence of self-reported postpartum hemorrhage (PPH) in Ga East, Accra, Ghana, and examine the demographic, biological, and social risk factors for PPH. METHODS: The present study was a cross-sectional secondary analysis of data collected during 2010-2012 from the Ghana Essential Health Interventions Program, a quasi-experimental interventional study surveying households in the urban Ga East Municipal District. The analysis included data from randomly selected parous women of childbearing age (15-49 years), excluding those with a history of abortion (spontaneous or induced) or stillbirth...
May 9, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29741731/expression-of-grim-19-in-unexplained-recurrent-spontaneous-abortion-and-possible-pathogenesis
#10
Yang Yang, Laiyang Cheng, Xiaohui Deng, Hongling Yu, Lan Chao
STUDY QUESTION: Is aberrant expression of gene associated with retinoid-interferon-induced mortality-19 (GRIM-19) associated with unexplained recurrent spontaneous abortion (URSA)? SUMMARY ANSWER: GRIM-19 deficiency may regulate regulatory T cell/ T helper 17 cell (Treg/Th17) balance partly through reactive oxygen species (ROS) - mammalian target of rapamycin (mTOR) signaling axis in URSA. WHAT IS KNOWN ALREADY: Immunological disorders may cause impaired maternal immune tolerance to the fetus and result in fetal rejection...
May 8, 2018: Molecular Human Reproduction
https://www.readbyqxmd.com/read/29739005/smoking-exposure-in-early-pregnancy-and-adverse-pregnancy-outcomes-usefulness-of-urinary-tobacco-specific-nitrosamine-metabolite-4-methylnitrosamino-1-3-pyridyl-1-butanol-levels
#11
Si Won Lee, You Jung Han, Dong Hee Cho, Ho-Seok Kwak, Kinarm Ko, Mi Hye Park, Jung Yeol Han
OBJECTIVES: The aim was to investigate the effect of -maternal smoking exposure assessed by urinary tobacco-specific nitrosamine metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-a1-butanol (NNAL) with adverse pregnancy outcomes. METHODS: A total of 251 pregnant women were recruited. Urinary cotinine and NNAL were measured. Participants' sociodemographics were obtained by questionnaire and pregnancy outcomes were collected by charts review after delivery. RESULTS: The prevalence of smoking was 8...
May 8, 2018: Gynecologic and Obstetric Investigation
https://www.readbyqxmd.com/read/29730033/incidence-and-biomarkers-of-pregnancy-spontaneous-abortion-and-neonatal-loss-during-an-environmental-stressor-implications-for-female-reproductive-suppression-in-the-cooperatively-breeding-meerkat
#12
Kristin A Dimac-Stohl, Charli S Davies, Nicholas M Grebe, Alexandra C Stonehill, Lydia K Greene, Jessica Mitchell, Tim Clutton-Brock, Christine M Drea
Meerkats are group-living, insectivorous herpestids in which subordinate members provide extensive care for the dominant female's young. In contrast to some cooperative breeders, subordinate female meerkats are physiologically able to reproduce and occasionally do so successfully; their attempts are more frequently 'suppressed' via eviction or infanticide by the dominant female. Spontaneous abortion and neonatal loss occur with some regularity, further negatively impacting reproductive success. Here, we compared the reproductive outcomes and endocrine profiles, including of serum progesterone (P4 ), serum estradiol (E2 ), and fecal glucocorticoid metabolites (fGCm), of dominant and subordinate dams residing within their clans in the Kalahari Desert of South Africa...
May 2, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29729842/human-amniotic-epithelial-cells-inhibit-activation-and-pro-inflammatory-cytokines-production-of-naive-cd4-t-cells-from-women-with-unexplained-recurrent-spontaneous-abortion
#13
Hossein Motedayyen, Abbas Rezaei, Amir-Hassan Zarnani, Nader Tajik
Unexplained recurrent spontaneous abortion (URSA) has been assumed to be caused by a defect in maternal immunological tolerance to the fetus. Human amniotic epithelial cells (hAECs) have stem cell-like features and the ability to modulate the innate and adoptive immune responses. This study aimed to investigate whether hAECs have immunomodulatory effects on naive CD4+ T cells from URSA patients. hAECs were obtained from 15 healthy pregnant women and phenotypic profile of hAECs was determined by flow cytometry...
May 2, 2018: Reproductive Biology
https://www.readbyqxmd.com/read/29729547/the-risk-of-herpes-simplex-virus-and-human-cytomegalovirus-infection-during-pregnancy-upon-adverse-pregnancy-outcomes-a-meta-analysis
#14
REVIEW
Ting-Li Shi, Li-Ju Huang, Yi-Quan Xiong, Yan-Yun Zhong, Jin-Jun Yang, Ting Fu, Xie-Fen Lei, Qing Chen
BACKGROUND AND OBJECTIVES: Herpes simplex virus (HSV) and human cytomegalovirus (HCMV) are widespread infections in humans, yet their impact on adverse pregnancy outcomes is controversial. The objective of this study was to evaluate the impact of HSV and HCMV infections during pregnancy on adverse pregnancy outcomes. METHODS: A systematic literature search was performed using Web of Science, Scopus, Medline, Embase, PubMed, and the Cochrane Library database for relevant publications up to 2nd August 2017...
April 25, 2018: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/29727533/-male-factors-and-countermeasures-for-recurrent-spontaneous-abortion
#15
Bao-Fang Jin
Recurrent spontaneous abortion (RSA) has a very complicated pathogenesis and male factors for this condition should not to be ignored, which are mainly related to genetics, immunology, infection, sperm quality, and others. In case of RSA, an etiological screening ought to be performed for the husband, which involves general, genetic and immunological examinations and infection detection. According to specific etiological factors, such measures as genetic consultation, immunotherapy, and traditional Chinese medication can be taken, which may contribute to the outcome of pregnancy...
October 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29720007/cytokine-induced-expression-of-nitric-oxide-synthases-in-chlamydia-trachomatis-infected-spontaneous-aborters
#16
Priya Prasad, Namita Singh, Banashree Das, Sheikh Raisuddin, Mridu Dudeja, Sangita Rastogi
PURPOSE: The aim of study was to evaluate expression of inducible nitric oxide synthase (iNOS), endothelial nitric oxide synthase (eNOS), interferon-gamma (IFN-γ), and tumor necrosis factor-alpha (TNF-α) in Chlamydia trachomatis (CT)-infected spontaneous aborters (SA). MATERIALS AND METHODS: Endometrial curettage tissue was collected from 140 SA (sporadic SA- 70; recurrent SA- 70) (Group I) and 140 age-matched controls (Group II) from Department of Obstetrics and Gynecology, Safdarjung Hospital, New Delhi, India...
May 2, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29718011/association-of-intron-2-variable-numbers-of-an-86-bp-tandem-repeat-polymorphisms-of-interleukin-1-receptor-antagonist-gene-and-idiopathic-recurrent-spontaneous-abortion
#17
Marco Antonio Avila-Vergara, Felipe de Jesús Peraza-Garay, Noemí Meraz-Cruz, Cesar Hernandez-Guerrero, Berenice Palacios-Gonzalez, Felipe Vadillo-Ortega
Background: It has been proposed that abnormal modulation of inflammatory response is involved in the physiopathology of idiopathic recurrent spontaneous abortion (iRSA). Factors that may participate in this process include the genetic background such as carrying specific polymorphisms of genes with functional effects. Objective: The objective is to study the association between iRSA and the frequency of intron-2 variable number tandem repeat-polymorphisms of interleukin-1 receptor antagonist gene (IL1RN)...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29716774/dengue-vaccination-during-pregnancy-an-overview-of-clinical-trials-data
#18
Anna Skipetrova, Tram Anh Wartel, Sophia Gailhardou
BACKGROUND: The live, attenuated, tetravalent dengue vaccine (CYD-TDV) is licensed in several endemic countries and contraindicated during pregnancy. Inadvertent vaccination during pregnancy may occur during clinical trials that include women of childbearing age. The potential risk associated with dengue vaccination in pregnancy remains unknown. We describe pregnancy outcomes following inadvertent dengue vaccination in pregnancy from CYD-TDV trial data. METHODS: Data were collected from trials conducted as part of the CYD-TDV clinical development...
April 28, 2018: Vaccine
https://www.readbyqxmd.com/read/29716658/a-case-report-of-spontaneous-abortion-caused-by-brucella-melitensis-biovar-3
#19
Hong-Xia Yang, Jun-Jun Feng, Qiu-Xiang Zhang, Rui-E Hao, Su-Xia Yao, Rong Zhao, Dong-Ri Piao, Bu-Yun Cui, Hai Jiang
BACKGROUND: Brucellosis is a worldwide zoonotic disease caused by Brucella spp. Brucella invades the body through the skin mucosa, digestive tract, and respiratory tract. However, only a few studies on human spontaneous abortion attributable to Brucella have been reported. In this work, the patient living in Shanxi Province in China who had suffered a spontaneous abortion was underwent pathogen detection and Brucella melitensis biovar 3 was identified. CASE PRESENTATION: The patient in this study was 22 years old...
May 2, 2018: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29709100/a-comparison-of-effectiveness-among-frequent-treatments-of-recurrent-spontaneous-abortion-a-bayesian-network-meta-analysis
#20
Sha Lv, Jing Yu, Xiaoxiao Xu
OBJECTIVE: A comprehensive network meta-analysis was designed to clarify contradictions and offer valuable clinical guidance in the treatment of recurrent spontaneous abortion (RSA). METHOD: The included clinical trials were selected from the relevant medical journal databases and screened. Treatments were ranked by the surface under the cumulative ranking curve. Heat plots were constructed to analyze the inconsistency between direct data and network results, and adjusted funnel plots were constructed to assess publication bias...
April 30, 2018: American Journal of Reproductive Immunology: AJRI
keyword
keyword
107011
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"