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Z J Sun, X D Zhang, L Ren, X Y Yang, J F Cai, X Li, X Zheng, W Wang
Objective: To explore the relationship between creatinine reduction ratio (CRR) and delayed graft function among kidney transplant recipients from donor of cardiac death (DCD). To define the value of CRR to predict delayed graft function (DGF) in early post-transplant period. Method: 86 patients were included, who received renal transplantation from DCD during Jan 1(st) 2011 to Jun 30(th) 2016. We performed a retrospective study and collected creatinine data within 3 days post-operation and marked them with Cr1, Cr2 , Cr3, and then calculated creatinine reduction ratio day-2 (CRR 2) =(Cr1-Cr2)/Cr1×100% and creatinine reduction ratio day-3 (CRR 3)=[(Cr1-Cr2)/Cr1+ (Cr2-Cr3)/Cr2]/2×100%...
January 2, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Liyan Peng, Ketao Mu, Aiguo Liu, Liangqiang Zhou, Yueyue Gao, Imrit Tejvansh Shenoy, Zhigang Mei, Qingguo Chen
The purpose of this study was to explore the central mechanism of transauricular vagus nerve stimulation (taVNS) to human by fMRI and to find a suitable taVNS site for potential tinnitus treatment. 24 healthy subjects aged between 28 and 38 years were enrolled in the experiment. 8 subjects were stimulated in the auricular acupoints Kindey (CO10), Yidan (CO11), Liver (CO12) and Shenmen (TF4) in the left ear, 8 subjects were stimulated at the anterior wall of the auditory canal and left lower limb as an anterior stimulation group; 8 persons who were arranged in a sham group received taVNS at the left ear lobe and tail of the helix...
March 2018: Hearing Research
Xiangling Li, YanQiang Wang
Membranous nephropathy (MN) accompanying Neuromyelitis optica spectrum disorders (NMOSD) has rarely been described previously. We recently presented a 45-year-old Chinese male presenting with recurrent lower extremity pitting edema, or eyelid edema, proteinuria and hyperlipidemia. especially intractable hiccup and vomiting, painful tonic spasm (PTS) as the revealing symptom of a demyelinating disorder of central nervous system. The kindey biopsy specimen showed MN stage 2. Serological testing revealed antibodies AQP4, MRI head and spine revealed medulla oblongata and C1-C2 cervical vertebra lesions...
July 2017: Multiple Sclerosis and related Disorders
K Lehnertová, K Huml, R Pilka
OBJECTIVE: Case report describes a patient with acute ST elevation myocardial infarction with Q wave in 26 weeks gestation. DESIGN: Case report. SETTING: Department of Obstetrics and Gynecology, University Hospital, Palacky University, Olomouc. CASE REPORT: Medical history is complicated with a cadaveric transplantation of kindey, osteosarcoma of the left knee with a joint extraction and chemotherapy, serious hypothyreosis after spontaneous discontinuation of medication and missing fetal nasal bone at the ultrasound examination...
December 0: Ceská Gynekologie
Daniel Hertzberg, Linda Rydén, Ulrik Sartipy, Martin Holzmann
An acute worsening of renal function, so called acute kidney injury, is common in patients admitted to hospital. Acute kidney injury is associated with an increased long-term risk for chronic kidney disease, myocardial infarction, heart failure, and death. In order to prevent further deterioration of kidney function early identification of causes for acute kindey injury is of utmost importance. In most cases, there is no specific treatment of acute kidney injury, but several general principles should be followed: to strive for normovolemia, optimize hemodynamics, treat electrolyte disturbances, discontinue nephrotoxic agents, and to adjust dosages of medications which are renally eliminated...
May 3, 2016: Läkartidningen
Shan Jian, Min Wei, Yan-Yan He, Wei Wang, Yu-Lin Kang, Zhi-Xing Sun
OBJECTIVE: To study the clinical features and gene mutations of 4 Chinese children with Dent disease. METHODS: The clinical and laboratory data of 4 children with Dent disease were analyzed retrospectively. Genetic testing of the 4 cases was carried out. RESULTS: All of 4 cases were boys. The first impression of Cases 1-3 was Fanconi syndrome. Proteinuria was presented as the first impression in Case 4. All 4 boys presented with low-molecular weight proteinuria (LMWP) and hypercalciuria, including 3 cases with hematuria, 1 case with kidney stones, 2 cases with nephrocalcinosis, 3 cases with hypophosphatemia, and 3 cases with rickets...
December 2015: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
Bo Liu, Feng Liang, Li-Ping Gu, Chao-Qing Wang, Xing-Hua Li, Yi-Min Jiang, Wei-Mei Li, Qing-Zhi Guo, Fang Ma
OBJECTIVE: To explore application of targeted contrast enhanced ultrasonography in diagnosis of early stage vascular endothelial injury and diabetic nephropathy. METHODS: Targeted SonoVue-TM microbubble was prepared by attaching anti-TM monoclonal antibody to the surface of ordinary microbubble SonoVue by biotin - avidin bridge method and ultrasonic instrument was used to evaluate the developing situation of targeted microbubble in vitro. Twenty 12-week-old male GK rats and 20 Wistar rats were enrolled in this study, and were randomly divided into targeted angiography group and ordinary angiography group...
August 2015: Asian Pacific Journal of Tropical Medicine
Efstathios Koulouridis, Ioannis Koulouridis
The first description of the renal tubules is attributed to Lorenzo Bellini in 1662 and four years later Marcello Malpighi described the glomerulus. In 1842 Sir William Bowman described the capsule that surrounds the Malpighian body and its connection with the renal tubule and introduced the "excretory" hypothesis of urine formation. In the same year, Carl Ludwig introduced the "filtration-reabsorption" hypothesis of urine formation. Bowman's hypothesis was accepted by the so-called "vitalists" and Ludwig's hypothesis by the so-called "mechanists"...
2014: Acta Medico-historica Adriatica: AMHA
Raymond Liang, Shauhab Chaudhry
A 37-year-old Caucasian male presented with what appeared clinically and diagnostically as testicular and kindey tomour's. However, syphilis serology and histology confirm that the lesions were gumma's. Without routine syphilis serology, the correct diagnosis may have been missed.
August 2013: International Journal of STD & AIDS
Kang Yong-An, Hu Yan-Rong, Gao Li, Yang Hai, Li Nan-Fang
Objective To investigate the expression of GIRK4 gene in the kidney tissues of obese rats. Methods Obese rat models were established using diet-induced method. The GIRK4 protein expression in kidney tissues was determined in 20 obese rats and 10 normal rats using Western blot analysis. Results The relative expression level of GIRK4 protein in the kidney tissues of obese rat (1.75±0.42) was significantly lower than that in normal rats (3.37±0.68, P<0.05). Conclusion GIRK4 has a low protein expression in the kidney tissues of obese rat...
March 2013: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
He Jin, Jin-Yu Li, Xing Yu, Lin Xu
OBJECTIVE: To evaluate influence of assemble flavone of rhizome drynaria (AFDR) on the value of the blood serum alkalinity phosphatase (ALP), calcium (Ca), phosphorus (P), creatinine (Cr) and glutamic-pyruvic transaminase (GPT) in rats model with skull defects. METHODS: Sixty SD male rats with age of 6-month were feeded for a week and then were randomly divided into control group and AFDR group, with 30 rats in each group. Left and right skull of rats were perforated with electromotive drill and the model of skull defects was made...
September 2012: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
Yuncheng Xia, Canhui Peng, Zhifang Zhou, Ping Cheng, Lin Sun, Youming Peng, Ping Xiao
OBJECTIVE: To explore the changes and clinical significance of saliva urea, creatinine (Cr), uric acid (UA) in both healthy people and chronic kidney disease (CKD) patients, and to provide a noninvasive, quick, accurate and reliable test to diagnose kindey disease. METHODS: Urea, Cr and UA in the saliva and serum collected from both healthy people and the CKD patients were measured by biochemical analyzer. We calculated the correlation coefficient of Urea, Cr and UA between the saliva and serum, compared the levels of saliva Urea, Cr and UA among CKD patients in different periods, drew the receiver operation characteristic (ROC) curve and analyzed the sensitivity and specificity of saliva Urea, Cr and UA to predict CKD patients in various periods...
November 2012: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
R Olbromski, E Siadkowska, B Zelazowska, L Zwierzchowski
Allelic expression imbalance (AEI) is an important genetic factor being the cause of differences in phenotypic traits that can be heritable. Studying AEI can be useful in searching for factors that modulate gene expression and help to understand molecular mechanisms underlying phenotypic changes. Although it was commonly recognized in many species and we know many genes show allelic expression imbalance, this phenomena was not studied on a larger scale in cattle. Using the pyrosequencing method we analyzed a set of 29 bovine genes in order to find those that have preferential allelic expression...
February 2013: Molecular Biology Reports
Juan Wang, Zhangqing Ma, Zongyuan Hong, Jianguo Song
OBJECTIVE: To determine the concentration in mice of danshensu from sodium danshensu and Salvia miltiorrhiza injection and undertake comparative study of them as well as to assess the effect of other components of S. miltiorrhiza injection on the tissue distribution of danshensu. METHOD: Mice received intraperitoneal administration of sodium danshensu or S. miltiorrhiza injection (equal to danshensu 60 mg x kg(-1)) respectively, and was executed 30 minutes after administration...
June 2011: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
Fernando Talarico, Pierfrancesco Buli, Domenico Iusco, Antonio Sangiorgi
The prognosis of stage IV renal cell carcinoma is very poor, since non-operative modalities for advanced renal carcinoma have failed to yield effective results. In fact, there is no indication for radiotherapy and systemic chemotherapy is not effective. Surgery, when indicated, seems to be the only therapeutic option possible.. Hepatectomy for metastatic renal cell carcinoma is very rarely reported, because multiple organ metastases ordinarily coexist. We report a case of a 61-year-old woman with a bilateral renal clear cell carcinoma, two synchronous liver metastasisi synchronous hepatic metastasis that were treated simultaneously with radical right nephrectomy, left upper pole kidney tumorectomy and right lateral liver sectorectomy...
March 2013: Annali Italiani di Chirurgia
G Vergoulas, P Boura, G Efstathiadis
The improvement in the field of kidney transplantation, during the last decades, has brought kindey transplantation to the top of patient preference as the best kidney replacement therapy. The use of marginal kidney grafts, which are highly immunogenic has become common practice because of lack of kidney donors. Inflammatory activity in the kidneys after brain death is an ongoing phenomenon. The inappropriate treatment of brain dead donor may result to primary non function (PNF) of the graft, delayed graft function (DGF) or to long term graft dysfunction and shortened graft survival...
October 2009: Hippokratia
Krishnamoorthy Karthikesan, Leelavinothan Pari
Ethanol is one of the most widely used and abused drugs that increases lipid levels in human and experimental animals. The objective of this study was to determine the effect of caffeic acid (CA) on alcohol-induced alterations of lipid levels in serum, liver and kindey of Wistar rats. The alcohol toxicity was induced by oral administration of ethanol (7.9 g/kg/bw) for 45 days through intragastric intubation. The elevation in the levels of lipids upon alcohol administration was accompanied by a significant increase in the levels of cholesterol, phospholipids (PL), free fatty acids (FFA) and triglycerides (TG) in serum, liver and kidney...
October 2008: Fundamental & Clinical Pharmacology
Yang Liu, Jin-Xia Kuai, Yan-Wei Zhang, Ying-Yuan Wang
OBJECTIVE: To observe the degradation of actin in cardiac muscle, brain and skeletal muscle of rats after death and to find an objective parameter interval (PMI) estimation. METHODS: Twenty eight clear Sprague Dawley rats put into an artificial climate incubator (set at 20 degrees C) for 0, 24, 48, 72, The actin contents in the above tissues were quantitated by Western-blot Pro Plus 5.0 image analysis system, and were then statistically analyzed RESULTS: Actin content in all these tissues decreased gradually with prolonged differences between the groups was statistically significant (P < 0...
June 2008: Fa Yi Xue za Zhi
Rui Hui, Min Zhang, Xiao-Meng Hao, Jin Zhang
OBJECTIVE: To evaluate tolerance and toxicity of high-dose epirubicin regimen CEF-100 as adjuvant therapy for breast cancer. METHODS: From March 2005 to October 2006, 98 patients with stage I - III a breast cancer were randomly assigned to receive postoperative chemotherapy with CEF-100 regimen (epirubicin 100 mg/m2, dl per 21 days for 6 cycles, n =48) or CEF-60 regimen (epirubicin 60 mg/m2, dl per 21 days for 6 cycles, n = 50). Blood routine test were done every cycle, liver and kindey function were examined and adverse effects were recorded after every cycle...
November 2007: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
C S C Bouman
OBJECTIVE: To summarize the general guidelines for drug dosing in critically-ill patients with acute kidney injury and continuous venovenous haemofiltration (CVVH), and to discuss whether the predicted dose adjustment is an as reliable estimate than one based on observed data, considering the recent literature. METHODS: Literature search was done in PubMed database for human studies. CONCLUSIONS: In critically-ill patients receiving CVVH, dosing of antibiotics based on the predicted clearances yield rough estimates...
2007: Acta Clinica Belgica
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