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https://www.readbyqxmd.com/read/29667148/sublingual-nodules-diagnostic-markers-of-metastatic-breast-cancer
#1
Xue Yang, Cui-Hong Zhu, Rui Cao, Jian Hao, Xiong-Zhi Wu
OBJECTIVE: To evaluate the diagnostic significance of sublingual nodules for metastasis of patients with breast cancer and further to explore the mechanisms of sublingual nodules. METHODS: The image data of 117 in-patients with breast cancer in stage I-IV in Tianjin Medical University Cancer Institute and Hospital from December 2009 to September 2011 were assessed retrospectively. All photos of patients' tongue were recorded by the digital camera of uniform type within 1 month after serological examination and regular re-examined by computed tomography (CT), magnetic resonance imaging and positron emission tomography CT...
April 17, 2018: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29665077/gliovascular-changes-precede-white-matter-damage-and-long-term-disorders-in-juvenile-mild-closed-head-injury
#2
Beatriz Rodriguez-Grande, Andre Obenaus, Aleksandra Ichkova, Justine Aussudre, Thomas Bessy, Elodie Barse, Bassem Hiba, Gwénaëlle Catheline, Grégory Barrière, Jerome Badaut
Traumatic brain injury (TBI) is a leading cause of hospital visits in pediatric patients and often leads to long-term disorders even in cases of mild severity. White matter (WM) alterations are commonly observed in patients months or years after the injury assessed by magnetic resonance imaging (MRI), but little is known about WM pathophysiology early after mild pediatric TBI. To evaluate the status of the gliovascular unit in this context, mild TBI was induced in postnatal-day 17 mice using a closed head injury model with two grades of severity (G1, G2)...
April 17, 2018: Glia
https://www.readbyqxmd.com/read/29664973/introducing-automation-to-the-molecular-diagnosis-of-trypanosoma-cruzi-infection-a-comparative-study-of-sample-treatments-dna-extraction-methods-and-real-time-pcr-assays
#3
Alba Abras, Cristina Ballart, Teresa Llovet, Carme Roig, Cristina Gutiérrez, Silvia Tebar, Pere Berenguer, María-Jesús Pinazo, Elizabeth Posada, Joaquim Gascón, Alejandro G Schijman, Montserrat Gállego, Carmen Muñoz
BACKGROUND: Polymerase chain reaction (PCR) has become a useful tool for the diagnosis of Trypanosoma cruzi infection. The development of automated DNA extraction methodologies and PCR systems is an important step toward the standardization of protocols in routine diagnosis. To date, there are only two commercially available Real-Time PCR assays for the routine laboratory detection of T. cruzi DNA in clinical samples: TCRUZIDNA.CE (Diagnostic Bioprobes Srl) and RealCycler CHAG (Progenie Molecular)...
2018: PloS One
https://www.readbyqxmd.com/read/29664336/left-ventricular-myocardial-deformation-on-cine-mr-images-relationship-to-severity-of-disease-and-prognosis-in-amyloid-light-chain-amyloidosis
#4
Ke Wan, Jiayu Sun, Dan Yang, Hong Liu, Jie Wang, Wei Cheng, Qing Zhang, Zhi Zeng, Tianjing Zhang, Andreas Greiser, Marie-Pierre Jolly, Yuchi Han, Yucheng Chen
Purpose To measure left ventricular (LV) myocardial strain with cine magnetic resonance (MR) imaging and a deformable registration algorithm (DRA) and to assess the prognostic value of myocardial strain in patients with light-chain (AL) amyloidosis. Materials and Methods In this prospective study, 78 consecutive patients with AL amyloidosis who underwent contrast material-enhanced cardiac MR imaging were enrolled at West China Hospital. LV myocardial strains and late gadolinium enhancement (LGE) were evaluated...
April 17, 2018: Radiology
https://www.readbyqxmd.com/read/29664051/predictive-value-of-cranial-ultrasound-for-neurodevelopmental-outcomes-of-very-preterm-infants-with-brain-injury
#5
Xue-Hua Zhang, Shi-Jun Qiu, Wen-Juan Chen, Xi-Rong Gao, Ya Li, Jing Cao, Jing-Jing Zhang
Background: Compared with full-term infants, very preterm infants are more vulnerable to injury and long-term disability and are at high risk of death. The predictive value of ultrasound and imaging on the neurodevelopment is one of the hot topics. This study aimed to investigate the relationship between cranial ultrasound (cUS) variables and neurodevelopmental outcomes of very preterm infants. Methods: Totally 129 very preterm infants (gestational age ≤28 weeks) in neonatal intensive care unit of Hunan Children's Hospital between January 2012 and November 2014 were included in this retrospective study...
April 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29662675/anterior-versus-posterior-approach-to-treat-cervical-spondylotic-myelopathy-clinical-and-radiological-results-with-long-period-of-follow-up
#6
Ziad A Audat, Mohammad D Fawareh, Ahmad M Radydeh, Moutasem M Obeidat, Mohannad A Odat, Khaldoon M Bashaireh, Mohammad M Barbarawi, Murad T Nusairat, Amna B Ibraheem, Mohammad Z Audat
Background: Cervical spondylotic myelopathy increases with age, but not all cases are symptomatic. It is usually diagnosed clinically and radiologically (X-ray and magnetic resonance imaging). Surgical treatment is indicated in severe symptomatic cases, while treatment controversy exists in the presence of less severe cases. Anterior and posterior approaches are generally used for decompression with no significant differences in the results of both. Methods: A total of 287 patients of cervical spondylotic myelopathy were treated at our hospital between January 2004 and December 2015...
2018: SAGE Open Medicine
https://www.readbyqxmd.com/read/29661945/cigarette-smoking-and-incident-heart-failure-insights-from-the-jackson-heart-study
#7
Daisuke Kamimura, Loretta R Cain, Robert J Mentz, Wendy B White, Michael J Blaha, Andrew P DeFilippis, Ervin R Fox, Carlos J Rodriguez, Rachel J Keith, Emelia J Benjamin, Javed Butler, Aruni Bhatnagar, Rose M Robertson, Michael D Winniford, Adolfo Correa, Michael E Hall
Background -Cigarette smoking has been linked with several factors associated with cardiac dysfunction. We hypothesized that cigarette smoking is associated with left ventricular (LV) structure and function, and incident heart failure (HF) hospitalization. Methods -We investigated 4129 (never smoker n=2884, current smoker n=503, and former smoker n=742) black participants (mean age, 54 years; 63% women) without a history of HF or coronary heart disease at baseline in the Jackson Heart Study. We examined the relationships between cigarette smoking and LV structure and function by using cardiac magnetic resonance imaging among 1092 participants, cigarette smoking and brain natriuretic peptide levels among 3325 participants, and incident HF hospitalization among 3633 participants with complete data...
April 16, 2018: Circulation
https://www.readbyqxmd.com/read/29660549/perineural-spread-along-spinal-and-obturator-nerves-in-primary-vaginal-carcinoma-a-case-report
#8
Eun Jee Song, Ji Seon Park, Kyung Nam Ryu, So Young Park, Wook Jin
BACKGROUND: Perineural spread is not uncommon feature in carcinoma of the head and neck. On the contrary, perineural spread in pelvic malignancies has been rarely reported. This report is the first report about perineural spread of obturator nerve and lumbosacral plexus from primary vaginal cancer. CASE DESCRIPTION: A 50-year-old woman diagnosed with infectious spondylitis at an outside hospital was referred to our institution. She presented with persistent lower back pain and right anterior thigh pain...
April 13, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29657440/magnetic-growth-modulation-in-orthopaedic-and-spine-surgery
#9
REVIEW
Adam E M Eltorai, Carolina Fuentes
Purpose: To examine distraction-based methods for treatment of early onset scoliosis (EOS), focusing on the magnetically controlled growing rod system (MCGR) relative to traditional growing rod system (TGR). To briefly discuss internal magnetically controlled nails for bone lengthening as another application of magnetic growth modulation. Results: Relative to TGR, MCGR involves fewer complications related to infection and general anesthesia because of fewer successive surgeries required...
March 2018: Journal of Orthopaedics
https://www.readbyqxmd.com/read/29656312/evaluation-of-taurine-neuroprotection-in-aged-rats-with-traumatic-brain-injury
#10
Raeesa Gupte, Sarah Christian, Paul Keselman, Joshua Habiger, William M Brooks, Janna L Harris
Despite higher rates of hospitalization and mortality following traumatic brain injury (TBI) in patients over 65 years old, older patients remain underrepresented in drug development studies. Worse outcomes in older individuals compared to younger adults could be attributed to exacerbated injury mechanisms including oxidative stress, inflammation, blood-brain barrier disruption, and bioenergetic dysfunction. Accordingly, pleiotropic treatments are attractive candidates for neuroprotection. Taurine, an endogenous amino acid with antioxidant, anti-inflammatory, anti-apoptotic, osmolytic, and neuromodulator effects, is neuroprotective in adult rats with TBI...
April 14, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29651818/effects-on-periocular-tissues-after-proton-beam-radiation-therapy-for-intraocular-tumors
#11
Youn Joo Choi, Tae Wan Kim, Suzy Kim, Hokyung Choung, Min Joung Lee, Namju Kim, Sang In Khwarg, Young Suk Yu
BACKGROUND: To present our experience on orbital and periorbital tissue changes after proton beam radiation therapy (PBRT) in patients with intraocular tumors, apart from treatment outcomes and disease control. METHODS: Medical records of 6 patients with intraocular tumors who had been treated with PBRT and referred to oculoplasty clinics of two medical centers (Seoul National University Hospital and Seoul Metropolitan Government-Seoul National University Boramae Medical Center) from October 2007 to September 2014 were retrospectively reviewed...
April 16, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29651699/direct-healthcare-costs-of-spinal-disorders-in-brazil
#12
Rodrigo Luiz Carregaro, Everton Nunes da Silva, Maurits van Tulder
OBJECTIVES: To investigate the direct healthcare costs of spinal disorders in Brazil, over 2016. METHODS: Prevalence-based cost-of-illness study, top-down approach and public healthcare system's perspective. International Classification of Diseases codes related to spinal disorders were included. The following costs were obtained: (1) hospitalization; medical professional service costs; intensive care unit costs; companion daily stay; (2) outpatient (services/procedures)...
April 12, 2018: International Journal of Public Health
https://www.readbyqxmd.com/read/29649697/intrapancereatic-abscess-due-to-arteriovenous-malformation-involving-the-entire-pancreas-a-case-report-and-review-of-the-literature
#13
Ahmad Almalki
INTRODUCTION: The described case is a patient with pancreatic arteriovenous malformation involving the entire pancreas and complicated with intrapancereatic abscess. PRESENTATION OF CASE: A 47 years-old was suffering from episodes of abdominal pain and vomiting with multiple hospital visits without reaching a diagnosis for four months. Contrast-enhanced computed tomography scan (CECT) done which shows a 1.6 × 1.4 cm fluid collection was seen in uncinate process of the pancreas, Magnetic resonance imaging (MRI) demonstrates abnormal vasculature involving the pancreas...
March 22, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29649674/are-there-clinical-and-neurophysiologic-predictive-factors-for-a-positive-response-to-hf-rtms-in-patients-with-treatment-resistant-depression
#14
Anna Poleszczyk, Maria Rakowicz, Tadeusz Parnowski, Jakub Antczak, Łukasz Święcicki
Better selection of patients with treatment-resistant depression for high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) would make the procedure more efficient. The objective of this study was to search for clinical and neurophysiologic predictors of therapeutic response with a special focus on the bipolar population. Forty patients (30 bipolar) underwent 20 daily sessions of HF-rTMS. Clinical outcome measures included the 21-item Hamilton Depression Rating Scale, the Beck Depression Inventory, the Clinical Global Impression, and the Patient Global Impression...
April 3, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29648690/incremental-value-of-left-atrial-active-function-measured-by-speckle-tracking-echocardiography-in-patients-with-hypertrophic-cardiomyopathy
#15
Kaori Fujimoto, Katsuji Inoue, Makoto Saito, Haruhiko Higashi, Tamami Kono, Teruyoshi Uetani, Jun Aono, Takayuki Nagai, Kazuhisa Nishimura, Jun Suzuki, Takafumi Okura, Shuntaro Ikeda, Satoshi Nakatani, Jitsuo Higaki
PURPOSE: Hypertrophic cardiomyopathy (HCM) impairs left ventricular (LV) diastolic function leading to left atrial (LA) dilatation. Because Doppler echocardiography cannot accurately assess LV diastolic function in hearts with heterogeneous hypertrophy, assessment of LA function might be useful for risk stratification of patients with HCM. This study aimed to elucidate the impact of LA function on outcome in patients with patients. METHODS: Seventy-six patients with HCM who underwent echocardiographic and cardiac magnetic resonance imaging were retrospectively enrolled...
April 12, 2018: Echocardiography
https://www.readbyqxmd.com/read/29644484/intracranial-control-and-survival-outcome-of-tyrosine-kinase-inhibitor-tki-alone-versus-tki-plus-radiotherapy-for-brain-metastasis-of-epidermal-growth-factor-receptor-mutant-non-small-cell-lung-cancer
#16
SooYoon Sung, Sea-Won Lee, Yoo-Kang Kwak, Jin Hyung Kang, Sook Hee Hong, Yeon-Sil Kim
INTRODUCTION: The efficacy of tyrosine kinase inhibitors (TKIs) with and without radiotherapy (RT) has not been determined in patients with brain metastases from epidermal growth factor receptor-mutant TKI naïve non-small cell lung cancer (NSCLC). METHODS: Between 2008 and 2016, 586 patients were diagnosed with NSCLC and treated with TKIs at a hospital in Seoul, South Korea; 81 of these patients met the eligibility criteria for our study. Outcomes analyzed included intracranial progression (ICP), neurological death, and overall survival (OS)...
April 11, 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29643905/comparison-of-application-values-of-ct-and-mri-in-the-diagnosis-of-early-lacunar-infarction
#17
Yuqing He, Liping Wei, Wenbo Li
Objective: To analyze and compare the values of computed tomography (CT) and magnetic resonance imaging (MRI) in the diagnosis of early lacunar infarction. Methods: Eighty-eight patients with early lacunar infarction who were admitted to the hospital were selected as research subjects, and all of them underwent MRI and CT. The study was conducted at our hospital between May 2015 to July 2016. Results: Four hundred and forty-one lesions were detected by MRI, and 145 were detected by CT...
January 2018: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29629911/national-study-of-nursing-research-characteristics-at-magnet%C3%A2-designated-hospitals
#18
Christine Pintz, Qiuping Pearl Zhou, Maureen Kirkpatrick McLaughlin, Katherine Patterson Kelly, Cathie E Guzzetta
OBJECTIVE: To describe the research infrastructure, culture, and characteristics of building a nursing research program in Magnet®-designated hospitals. BACKGROUND: Magnet recognition requires hospitals to conduct research and implement evidence-based practice (EBP). Yet, the essential characteristics of productive nursing research programs are not well described. METHODS: We surveyed 181 nursing research leaders at Magnet-designated hospitals to assess the characteristics in their hospitals associated with research infrastructure, research culture, and building a nursing research program...
April 6, 2018: Journal of Nursing Administration
https://www.readbyqxmd.com/read/29629684/hypertension-as-the-trigger-for-posterior-reversible-encephalopathy-syndrome-in-paediatric-renal-patients-an-important-diagnosis-that-should-not-be-missed
#19
J K Strong, K L Petersen, U Kala
BACKGROUND: Posterior reversible encephalopathy syndrome (PRES) is a reversible neurological condition presenting with seizures and visual disturbances and diagnosed on magnetic resonance imaging (MRI). Little is understood about its pathogenesis, particularly in children, but it is thought to be related to hypertension. OBJECTIVES: To review the presentation, diagnosis and outcome of PRES in paediatric renal patients at Chris Hani Baragwanath Academic Hospital, Johannesburg, South Africa, between 1 January 2000 and 31 January 2017 and compare these with published case reports to date...
March 28, 2018: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/29629315/surgical-resection-of-neuroendocrine-tumors-of-the-pancreas-pnets-by-minimally-invasive-surgery-the-laparoscopic-approach
#20
REVIEW
Tomoki Shirota, Yuichi Nagakawa, Yatsuka Sahara, Chie Takishita, Yosuke Hijikata, Yuichi Hosokawa, Tetsushi Nakajima, Hiroaki Osakabe, Kenji Katsumata, Akihiko Tsuchida
Neuroendocrine tumors of the pancreas (pNETs) are a rare group of neoplasms that originate from the endocrine portion of the pancreas. Tumors that either secrete or do not secrete compounds, resulting in symptoms, can be classified as functioning and non-functioning pNETs, respectively. The prevalence of such tumors has recently increased due to the use of more sensitive imaging techniques, such as multidetector computed tomography, magnetic resonance imaging and endoscopic ultrasound. The biological behavior of pNETs varies widely from indolent, well-differentiated tumors to those that are far more aggressive...
February 2018: Gland Surgery
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