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https://www.readbyqxmd.com/read/29671725/when-is-posting-about-patients-on-social-media-unethical-medutainment
#1
Katelyn G Bennett, Christian J Vercler
Social media is characterized by online spaces for rapid communication, advertising, professional development, and advocacy, and these platforms have revolutionized the way we interact with people and our culture. In plastic surgery, platforms like Facebook, Snapchat, and Instagram are especially attractive for practice promotion and instantaneous connection with potential patients. However, considerable risks and ethical dilemmas lie in wait for the plastic surgeon who attempts to use patient photographs and videos for advertising...
April 1, 2018: AMA Journal of Ethics
https://www.readbyqxmd.com/read/29659777/number-of-pregnancies-and-subsequent-phenotype-in-a-cross-sectional-cohort-of-women-with-arrhythmogenic-cardiomyopathy
#2
Anna I Castrini, Øyvind H Lie, Ida S Leren, Mette E Estensen, Mathis K Stokke, Lars G Klæboe, Thor Edvardsen, Kristina H Haugaa
Aims: We aimed to assess the relation between number of pregnancies and cardiac structure, function, and arrhythmic events in women with arrhythmogenic cardiomyopathy (AC). Methods and results: We included female AC patients in a cross-sectional study. Number of pregnancies and pregnancy related symptoms were recorded. Ventricular arrhythmias were defined as aborted cardiac arrest, sustained ventricular tachycardia, or appropriate implantable cardioverter-defibrillator therapy...
April 6, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29651518/updating-impairments-and-the-failure-to-explore-new-hypotheses-following-right-brain-damage
#3
Elisabeth Stöttinger, Carolyn Louise Guay, James Danckert, Britt Anderson
We have shown recently that damage to the right hemisphere impairs the ability to update mental models when evidence suggests an old model is no longer appropriate. We argue that this deficit is generic in the sense that it crosses multiple cognitive and perceptual domains. Here, we examined the nature of this updating impairment to determine more precisely the underlying mechanisms. We had right (RBD, N = 12) and left brain damaged (LBD, N = 10) patients perform versions of our picture-morphing task in which pictures gradually morph from one object (e...
April 12, 2018: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/29625137/sensitivity-of-non-contrast-computed-tomography-for-small-renal-calculi-with-endoscopy-as-the-gold-standard
#4
Naeem Bhojani, Jessica E Paonessa, Marawan M El Tayeb, James C Williams, Tariq A Hameed, James E Lingeman
OBJECTIVES: To compare the sensitivity of non-contrast CT to endoscopy for detection of renal calculi. Imaging modalities for detection of nephrolithiasis have centered on abdominal x-ray (KUB), ultrasound (US), and non-contrast computed tomography (CT). Sensitivities of 58-62% (KUB), 45% (US), and 95-100% (CT) have been previously reported. However, these results have never been correlated with endoscopic findings. METHODS: Idiopathic calcium oxalate stone formers with symptomatic calculi requiring ureteroscopy (URS) were studied...
April 3, 2018: Urology
https://www.readbyqxmd.com/read/29618091/longitudinal-analysis-of-antibody-cross-neutralization-following-zika-and-dengue-virus-infection-in-asia-and-the-americas
#5
Magelda Montoya, Matthew Collins, Wanwisa Dejnirattisai, Leah C Katzelnick, Henry Puerta-Guardo, Ramesh Jadi, Samuel Schildhauer, Piyada Supasa, Sirijitt Vasanawathana, Prida Malasit, Juthathip Mongkolsapaya, Aruna D de Silva, Hasitha Tissera, Angel Balmaseda, Gavin Screaton, Aravinda M de Silva, Eva Harris
Background: The four dengue virus serotypes (DENV1-4) and Zika virus (ZIKV) are related mosquito-borne flaviviruses of major importance globally. While monoclonal antibodies and plasma from DENV-immune donors can neutralize or enhance ZIKV in vitro and in small animal models, and vice versa, the extent, duration, and significance of cross-reactivity remains unknown, particularly in flavivirus-endemic regions. Methods: We studied neutralizing antibodies to ZIKV and DENV1-4 in longitudinal serologic specimens through 3 years post-infection from people in Latin America and Asia with laboratory-confirmed DENV infections...
April 2, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29610631/the-effect-of-propofol-on-chronic-headaches-in-patients-undergoing-endoscopy
#6
David Giampetro, Victor Ruiz-Velasco, Ashlee Pruett, Matthew Wicklund, Robert Knipe
Objective: This study determined acute and long-term effects of propofol administration in patients with severe headaches undergoing endoscopic procedures. Background: Approximately 13% of the US population is affected by migraines or severe headaches. The effect of propofol on headaches more than a few days after the intervention has not been explored. Methods: We employed a nonrandomized, prospective observational study that recruited patients with chronic headaches who received propofol from an outpatient endoscopy center for either upper or lower endoscopies...
2018: Pain Research & Management: the Journal of the Canadian Pain Society
https://www.readbyqxmd.com/read/29606539/anatomy-of-the-pudendal-nerve-and-other-neural-structures-around-the-proximal-hamstring-origin-in-males
#7
Gregory L Cvetanovich, Bryan M Saltzman, Gift Ukwuani, Rachel M Frank, Nikhil N Verma, Charles A Bush-Joseph, Shane J Nho
PURPOSE: To define the anatomy of the pudendal nerve in relationship to the proximal hamstring and other nearby neurological structures during proximal hamstring repair. METHODS: Six fresh-frozen human cadaveric hemi-pelvises from male patients ages 64.0 ± 4.1 years were dissected in prone position with hips in 10° flexion to identify the relationship of proximal hamstring origin to surrounding neurologic structures including the pudendal nerve, sciatic nerve, and posterior femoral cutaneous nerve...
March 29, 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29600103/report-of-a-lung-carcinoma-extended-to-the-left-atrium-through-pulmonary-vein
#8
Federico Cipriano, Lycio U Dessoti, Alfredo José Rodrigues, Walter Vilella de Andrade Vicente, Fernando Chahud, Paulo Roberto B Evora
Lung cancers may extend along or grow through the pulmonary veins to invade or lie within the left atrium (LA). A 62-year-old man, previously healthy, presented with 1-month ventilatory-independent right hemithorax back pain, dry cough and large effort dyspnea. He also referred weight loss of 12 kg in 10 months and denied hemoptysis. As antecedents, he smoked for 40 years and moderate daily alcoholism. On physical examination, the patient was in good general condition, hydrated and regular respiration at rest [blood pressure (BP) =120/80 mmHg; heart rate (HR) =90 bpm; respiratory rate (RR) =16 rpm]...
January 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29573386/-lying-in-dementia-care
#9
Sabrina Cerrone, Concetta Paola Pelullo, Daniela Cantone
The indiscriminate use of lying, when communicating with patients with dementia, is questioned in terms of ethics and acceptability. In this article we present the concept of "therapeutic lying", to describe those situations where a "non-truth" is used in the patient's interest and not that of the healthcare professional. The debate is still open, so it is necessary to better clarify risks and benefits of lying in the context of care, both to safeguard patients and to allow healthcare professionals to respect ethical and moral standards...
November 2017: Igiene e Sanità Pubblica
https://www.readbyqxmd.com/read/29554876/clinical-utility-of-exome-sequencing-in-individuals-with-large-homozygous-regions-detected-by-chromosomal-microarray-analysis
#10
Aparna Prasad, Matthew A Sdano, Rena J Vanzo, Patricia A Mowery-Rushton, Moises A Serrano, Charles H Hensel, E Robert Wassman
BACKGROUND: Chromosomal microarray analysis (CMA) is recommended as the first-tier clinical diagnostic test for individuals with developmental disabilities. In addition to detecting copy number variations, CMA platforms with single nucleotide polymorphism probes can detect large homozygous regions within the genome, which represent potential risk for recessively inherited disorders. METHODS: To determine the frequency in which pathogenic or likely pathogenic variants can be detected in these regions of homozygosity, we performed whole exome sequencing (WES) in 53 individuals where homozygosity was detected by CMA...
March 20, 2018: BMC Medical Genetics
https://www.readbyqxmd.com/read/29549466/within-patient-fluctuation-of-brain-volume-estimates-from-short-term-repeated-mri-measurements-using-siena-fsl
#11
Roland Opfer, Ann-Christin Ostwaldt, Christine Walker-Egger, Praveena Manogaran, Maria Pia Sormani, Nicola De Stefano, Sven Schippling
BACKGROUND: Measurements of brain volume loss (BVL) in individual patients are currently discussed controversially. One concern is the impact of short-term biological noise, like hydration status. METHODS: Three publicly available reliability MRI datasets with scan intervals of days to weeks were used. An additional cohort of 60 early relapsing multiple sclerosis (MS) patients with MRI follow-ups was analyzed to test whether after 1 year pathological BVL is detectable in a relevant fraction of MS patients...
March 16, 2018: Journal of Neurology
https://www.readbyqxmd.com/read/29542844/the-effect-of-a-controlled-gluten-challenge-in-a-group-of-patients-with-suspected-non-coeliac-gluten-sensitivity-a-randomized-double-blind-placebo-controlled-challenge
#12
H F Dale, J G Hatlebakk, N Hovdenak, S O Ystad, G A Lied
BACKGROUND: Non-coeliac gluten-sensitivity (NCGS) has been proposed as a new entity with unknown prevalence and mechanisms, and there is a need for a standardized procedure to confirm the diagnosis. The objective of this study was to characterize the response to an oral gluten-challenge in patients with a symptom-relief when following a gluten free-diet (GFD). METHODS: Twenty patients (14F/6M, age range: 21-62 years) with suspected NCGS, without coeliac disease and wheat-allergy, were included while on a gluten-free diet...
March 15, 2018: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29536321/assessment-of-remote-myocardium-heterogeneity-in-patients-with-ventricular-tachycardia-using-texture-analysis-of-late-iodine-enhancement-lie-cardiac-computed-tomography-cct-images
#13
Antonio Esposito, Anna Palmisano, Sofia Antunes, Caterina Colantoni, Paola Maria Vittoria Rancoita, Davide Vignale, Francesca Baratto, Paolo Della Bella, Alessandro Del Maschio, Francesco De Cobelli
PURPOSE: Diffuse remodeling of myocardial extra-cellular matrix is largely responsible for left ventricle (LV) dysfunction and arrhythmias. Our hypothesis is that the texture analysis of late iodine enhancement (LIE) cardiac computed tomography (cCT) images may improve characterization of the diffuse extra-cellular matrix changes. Our aim was to extract volumetric extracellular volume (ECV) and LIE texture features of non-scarred (remote) myocardium from cCT of patients with recurrent ventricular tachycardia (rVT), and to compare these radiomic features with LV-function, LV-remodeling, and underlying cardiac disease...
March 13, 2018: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/29503174/posterior-inferior-cerebellar-artery-aneurysm-have-you-ever-been-misdiagnosed
#14
Yuan Zhang, Shiqing Sun, Qi Xu, Weihua Feng, Haisong Chen
RATIONALE AND OBJECTIVES: The posterior inferior cerebellar artery aneurysm (PICAA), especially distal PICAA, is easily missed by a doctor, leading to misdiagnosis and treatment delays. The objective of this article is to report the computed tomography angiography (CTA) presentations of 30 cases of PICAA proved by digital subtraction angiography (DSA) or surgical operation, and analyze the causes of misdiagnosis of PICAA by CTA. MATERIALS AND METHODS: Thirty cases of patients with PICAA that were proved by DSA or surgical operation were included in this study, all of whom underwent CTA before surgical procedure...
March 1, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29501059/review-of-oritavancin-for-the-treatment-of-acute-bacterial-skin-and-skin-structure-infections
#15
Ana Alejandra García Robles, Eduardo López Briz, María Dolores Fraga Fuentes, Rocío Asensi Diez, Jesús Francisco Sierra Sánchez
OBJECTIVE: To assess critically oritavancin, a second-generation  lipoglycopeptide, for the treatment of Acute Bacterial Skin and Skin Structure Infections caused by susceptible Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus. METHOD: An evaluation report of oritavancin in Acute Bacterial Skin and Skin  Structure Infections was carried out according to the methodology of the Group  for drug evaluation, standardization and research in drug selection of the  Spanish Society of Hospital Pharmacy (SEFH)1, with the MADRE 4...
March 1, 2018: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/29498448/variations-in-cancer-care-for-adolescents-and-young-adults-ayas-with-ductal-carcinoma-in-situ
#16
Amy Voci, Bradley Bandera, Emily Ho, Jihey Lee, Melanie Goldfarb, Maggie DiNome
NCCN guidelines recommend tamoxifen (TAM) for adjuvant treatment of ductal carcinoma in situ (DCIS). TAM has side effects that can potentially complicate treatment recommendations and patient acceptance. It is unknown how well-accepted this recommended therapy is for the adolescent and young adult (AYA) patient population with DCIS. The NCDB was used to identify patients aged 15-39 with DCIS treated between 2000 and 2012. Patient demographic, socioeconomic, and treatment data were collected. Chi-squared test and multivariate analysis were used for statistical assessment...
March 2, 2018: Breast Journal
https://www.readbyqxmd.com/read/29493876/movement-behaviour-in-adults-with-haemophilia-compared-to-healthy-adults
#17
M A Timmer, M F Pisters, P de Kleijn, R A de Bie, R E G Schutgens, C Veenhof
BACKGROUND: Limited research has been published regarding movement behaviour of adult persons with haemophilia (PWH). It is hypothesized that avoidance of activities and more sedentary behaviour cause poorer physical functioning. AIM: To determine differences in movement behaviour between PWH and healthy adults. METHODS: Movement behaviour was measured with an accelerometer distinguishing between; lying/non-wear, sitting, standing, walking, running and cycling...
March 1, 2018: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/29476532/research-imaging-of-brain-structure-and-function-after-concussion
#18
REVIEW
Catherine D Chong, Todd J Schwedt
Even when concussions are associated with prolonged physical and cognitive sequelae, concussions are typically "invisible" on diagnostic brain imaging, indicating that the neuropathology associated with concussion lies under the detection threshold of routine imaging. However, data from brain structural and functional research imaging studies using diffusion tensor imaging, resting-state functional magnetic resonance imaging, and brain perfusion imaging indicate that these imaging sequences have a role in identifying concussion-related neuropathology...
February 24, 2018: Headache
https://www.readbyqxmd.com/read/29471816/idiopathic-pulmonary-fibrosis-pathogenesis-and-management
#19
REVIEW
Giacomo Sgalla, Bruno Iovene, Mariarosaria Calvello, Margherita Ori, Francesco Varone, Luca Richeldi
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease characterized by the aberrant accumulation of fibrotic tissue in the lungs parenchyma, associated with significant morbidity and poor prognosis. This review will present the substantial advances achieved in the understanding of IPF pathogenesis and in the therapeutic options that can be offered to patients, and will address the issues regarding diagnosis and management that are still open. MAIN BODY: Over the last two decades much has been clarified about the pathogenic pathways underlying the development and progression of the lung scarring in IPF...
February 22, 2018: Respiratory Research
https://www.readbyqxmd.com/read/29471013/hepatic-arterial-infusion-of-oxaliplatin-plus-fluorouracil-leucovorin-versus-sorafenib-for-advanced-hepatocellular-carcinoma
#20
Ning Lyu, Yanan Kong, Luwen Mu, Youen Lin, Jibin Li, Yaru Liu, Zhenfeng Zhang, Lie Zheng, Haijing Deng, Shaolong Li, Qiankun Xie, Rongping Guo, Ming Shi, Li Xu, Xiuyu Cai, Peihong Wu, Ming Zhao
BACKGROUND & AIMS: To compare the overall survival (OS) and disease progression free survival (PFS) in patients with advanced hepatocellular carcinoma (Ad-HCC) who are undergoing hepatic arterial infusion (HAI) of oxaliplatin, fluorouracil/leucovorin (FOLFOX) treatment versus sorafenib. METHODS: This retrospective study was approved by the ethical review committee, and informed consent was obtained from all patients before treatment. HAI of FOLFOX (HAIF) was recommended as an alternative treatment option for patient who refused sorafenib...
February 19, 2018: Journal of Hepatology
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