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https://www.readbyqxmd.com/read/28816636/the-distress-thermometer-predicts-subjective-but-not-objective-cognitive-complaints-six-months-after-treatment-initiation-in-cancer-patients-receiving-a-curative-cancer-treatment
#1
Michelle Lycke, Tessa Lefebvre, Lies Pottel, Hans Pottel, Lore Ketelaars, Karin Stellamans, Koen Van Eygen, Philippe Vergauwe, Patrick Werbrouck, Laurence Goethals, Patricia Schofield, Tom Boterberg, Philip R Debruyne
OBJECTIVES: Research has indicated that cancer-related cognitive impairments (CRCI) may be influenced by psychosocial factors such as distress, worry and fatigue. Therefore, we aimed to validate the distress thermometer (DT) as a screening tool to detect CRCI six months post treatment initiation in a group of general cancer patients. METHODS: Patients(18 years, n 125) with a histologically confirmed diagnosis of a solid cancer or haematological malignancy, scheduled for a curative treatment, were evaluated at baseline (T0) and six months post-treatment initiation (T1) for CRCI by a neuropsychological assessment including patient-reported outcome measures (PROMs)...
August 17, 2017: Journal of Psychosocial Oncology
https://www.readbyqxmd.com/read/28815621/red-blood-cell-sedimentation-of-apheresis-granulocytes
#2
Michelle A Lodermeier, Karen M Byrne, Willy A Flegel
Sedimentation of Apheresis Granulocyte components removes red blood cells. It is used to increase the blood donor pool when blood group-compatible donors cannot be recruited for a patient because of a major ABO incompatibility or incompatible red blood cell antibodies in the recipient. Because granulocytes have little ABO and few other red blood cell antigens on their membrane, such incompatibility lies mostly with the contaminating red blood cells. Video Clip S1 shows the process of red blood cell sedimentation of an Apheresis Granulocyte component...
August 16, 2017: Transfusion
https://www.readbyqxmd.com/read/28813199/hypoglossal-canal-lesions-distinctive-imaging-features-and-simple-diagnostic-algorithm
#3
Steven M Weindling, Christopher P Wood, Joseph M Hoxworth
OBJECTIVE: The objective of this study is to compare the prevalence of hypoglossal canal lesions and identify differentiating imaging features. MATERIALS AND METHODS: A 15-year retrospective review of lesions of the hypoglossal nerve and hypoglossal canal, excluding those in patients with metastasis or prior head and neck cancer and those treated with radiation or surgery, was performed. Clinical findings and lesion imaging features were documented. The contrast-enhanced T1-weighted non-enhancing cystic component of hypoglossal schwannomas was compared with size-matched pathologically proven vestibular schwannomas...
August 16, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28810895/understanding-the-cluster-randomised-crossover-design-a-graphical-illustraton-of-the-components-of-variation-and%C3%A2-a-sample-size%C3%A2-tutorial
#4
Sarah J Arnup, Joanne E McKenzie, Karla Hemming, David Pilcher, Andrew B Forbes
BACKGROUND: In a cluster randomised crossover (CRXO) design, a sequence of interventions is assigned to a group, or 'cluster' of individuals. Each cluster receives each intervention in a separate period of time, forming 'cluster-periods'. Sample size calculations for CRXO trials need to account for both the cluster randomisation and crossover aspects of the design. Formulae are available for the two-period, two-intervention, cross-sectional CRXO design, however implementation of these formulae is known to be suboptimal...
August 15, 2017: Trials
https://www.readbyqxmd.com/read/28806093/critical-shoulder-angle-and-acromial-index-do-not-influence-24-month-functional-outcome-after-arthroscopic-rotator-cuff-repair
#5
Merrill Lee, Jerry Yongqian Chen, Ming Han Lincoln Liow, Hwei Chi Chong, Paul Chang, Denny Lie
BACKGROUND: Recent studies have shown a correlation between scapular geometry and the development of atraumatic rotator cuff tears. However, a paucity of literature is available on the effects of critical shoulder angle (CSA) and acromial index (AI) on functional outcomes after arthroscopic rotator cuff repair. Hypothesis/Purpose: The purpose was to investigate the influence of CSA and AI on 24-month functional outcomes after arthroscopic rotator cuff repair. The hypothesis was that a larger CSA or AI would result in poorer postoperative outcomes...
August 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28796132/optimal-point-of-insertion-and-needle-angle-in-neuraxial-blockade-using-a-midline-approach-a-study-in-computed-tomography-scans-of-adult-patients
#6
Mark Vogt, Dennis J van Gerwen, Wouter Lubbers, John J van den Dobbelsteen, Martin Hagenaars
BACKGROUND AND OBJECTIVES: Neuraxial blockade using a midline approach can be challenging. Part of this challenge lies in finding the optimal approach of the needle to its target. The present study aimed at finding (1) the optimal point of insertion of the needle between the tips of 2 adjacent spinous processes and (2) the optimal angle relative to the skin at which the needle should approach the epidural or subarachnoid space. METHODS: A computer algorithm systematically analyzed computed tomography scans of vertebral columns of a cohort of 52 patients...
September 2017: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/28795666/-value-of-serum-crispld2-levels-for-the-diagnosis-and-prognosis-evaluation-of-sepsis-patients
#7
Lai Wang, Xiufen Yang, Shuli Zhang, Mengsha Zhu
OBJECTIVE: To investigate the value of cysteine-rich secretory protein LCCL domain-containing 2 (CRISPLD2) in diagnosis and prognosis in patients with sepsis. METHODS: Clinical data of patients admitted to intensive care unit (ICU) of the First Hospital of Hebei Medical University from December 2014 to December 2016 were retrospectively analyzed. According to the severity of sepsis, the patients were divided into three groups: sepsis patients, severe sepsis patients and septic shock patients, and 100 healthy persons were enrolled as control group...
August 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28782415/no-difference-in-neck-enlargement-for-patients-treated-with-double-proximal-self-expandable-suprarenal-fixation-endografting
#8
Andrés Reyes Valdivia, Georgios Pitoulias, África Duque Santos, Martín Fabregate Fuente, Apostolos G Pitoulias, Julia Ocaña Guaita, Claudio Gandarias
INTRODUCTION: Neck enlargement is well described in patients treated with self-expandable endografts for abdominal aortic aneurysms. Double endografting (ie, overlapping of stent grafts) occurs in patients with proximal cuffs or bifurcated to monoiliacal configuration conversions. When the aortic neck of patients receives 2 suprarenal fixation endografts, it may behave differently in terms of radial force and interaction of additional suprarenal stents extending to the visceral aorta...
January 1, 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28777699/multidetector-ct-for-evaluation-of-the-extrapleural-space
#9
Mario G Santamarina, Ignacio Beddings, Guillermo V Lermanda Holmgren, Hector Opazo Sanchez, Mariano M Volpacchio
The extrapleural space (EPS) is an anatomic space at the periphery of the chest that can be involved in a number of disease processes. This space lies between the inner surface of the ribs and the parietal pleura and contains adipose tissue, loose connective tissue, lymph nodes, vessels, endothoracic fascia, and the innermost intercostal muscle. It is often overlooked on cross-sectional imaging studies and almost invariably overlooked on conventional radiographic studies. At conventional radiography, the EPS occasionally can be seen when there is extrapleural fat proliferation, which might be confused with pleural thickening or pleural effusion...
August 4, 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28774238/wide-awake-hand-surgery
#10
Line Lied, Grethe E Borchgrevink, Vilhjalmur Finsen
BACKGROUND: "Wide awake hand surgery", where surgery is performed in local anaesthesia with adrenaline, without sedation or a tourniquet, has become widespread in some countries. It has a number of potential advantages and we wished to evaluate it among our patients. METHODS: All 122 patients treated by this method during one year were evaluated by the surgeons and the patients on a numerical scale from 0 (best/least) to 10 (worst/most). Theatre time was compared to that recorded for a year when regional or general anaesthesia had been used...
September 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28768079/hyperbaric-medicine-today-an-historically-noble-discipline-challenged-by-loss-of-critical-access-and-overutilization-invited-commentary
#11
Richard Clarke
As the title implies, much appears amiss with hyperbaric medicine. Long recognized for its life-saving, CNS-sparing,infection-fighting and tissue-salving attributes, its current application has been rightly called into question by a broad cross-section of health care delivery system stakeholders [1, 2, 3, 4, 5]. This paper will examine what lies behind the stunning loss of availability for a majority of the Federal Drug Administration-approved uses, arguably those for which patients have the most to gain. It will address overutilization in the context of an erosion of practice standards and widespread manipulation of the reimbursement process...
January 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28761061/tepapa-a-novel-in-silico-feature-learning-pipeline-for-mining-prognostic-and-associative-factors-from-text-based-electronic-medical-records
#12
Frank Po-Yen Lin, Adrian Pokorny, Christina Teng, Richard J Epstein
Vast amounts of clinically relevant text-based variables lie undiscovered and unexploited in electronic medical records (EMR). To exploit this untapped resource, and thus facilitate the discovery of informative covariates from unstructured clinical narratives, we have built a novel computational pipeline termed Text-based Exploratory Pattern Analyser for Prognosticator and Associator discovery (TEPAPA). This pipeline combines semantic-free natural language processing (NLP), regular expression induction, and statistical association testing to identify conserved text patterns associated with outcome variables of clinical interest...
July 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28758705/coping-with-changes-and-uncertainty-a-qualitative-study-of-young-adult-cancer-patients-challenges-and-coping-strategies-during-treatment
#13
Nataskja-Elena Kersting Lie, Torill Marie Bogsnes Larsen, May Aasebø Hauken
Young adult cancer patients (YACPs), aged 18-35 years when diagnosed with cancer, are in a vulnerable transitioning period from adolescence to adulthood, where cancer adds a tremendous burden. However, YACPs' challenges and coping strategies are under-researched. The objective of this study was to explore what challenges YACP experience during their treatment, and what coping strategies they applied to them. We conducted a qualitative study with a phenomenological-hermeneutic design, including retrospective, semi-structured interviews of 16 YACPs who had undergone cancer treatment...
July 31, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28756422/transradial-coronary-angiogram-in-a-sitting-position
#14
Konstantinos Marmagkiolis, Mehmet Cilingiroglu, Cindy L Grines
Transradial coronary angiography has significantly increased in the United States over the last decade. When the patient is unable to lie down despite analgesia and conscious sedation, general anesthesia may be recommended. We report the feasibility of transradial coronary angiogram in a sitting position.
August 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/28750920/antibiotic-stewardship-does-it-work-in-hospital-practice-a-review-of-the-evidence-base
#15
REVIEW
Marlies E J L Hulscher, Jan M Prins
BACKGROUND: Guidelines for developing and implementing stewardship programmes include recommendations on 'appropriate antibiotic use' to guide the stewardship team's choice of potential stewardship objectives. They also include recommendations on 'behavioural change interventions' to guide the team's choice of potential interventions to ensure that professionals actually use antibiotics appropriately in daily practice. AIMS: This paper aims to summarize the evidence base of both appropriate antibiotic use recommendations (the "what") and behavioural change interventions (the "how") in hospital practice...
July 24, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28747080/external-validation-of-a-rectal-cancer-outcome-prediction-model-with-a-cohort-of-patients-treated-with-preoperative-radiochemotherapy-and-deep-regional-hyperthermia
#16
K Zwirner, P Bonomo, U Lamprecht, D Zips, C Gani
PURPOSE: To validate a nomogram for the prediction of treatment outcomes after preoperative radiochemotherapy and surgery for locally advanced rectal cancer with a cohort of patients treated with additional deep regional hyperthermia. PATIENTS AND METHODS: A total of 86 patients were treated with preoperative radiochemotherapy and deep regional hyperthermia at our institution. For every patient, the 5-year probability for death, distant metastases and local failure based on a previously published nomogram were calculated and patients were divided into three risk groups...
July 26, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28741328/-short-term-results-of-weils-osteotomy-in-patients-with-propulsive-metatarsalgia
#17
J C Hernández-Martínez, J Vázquez-Escamilla, M Coronado-Puente
INTRODUCTION: Metatarsalgia is the most common reason for consultation in orthopedic pathology of the foot. The key to its treatment lies in the correct determination of the symptoms, which are biological, morphological and mechanical alterations responsible for pain. Weil´s osteotomy is commonly used for multiple forefoot pathologies, including metatarsalgias. MATERIAL AND METHODS: We included patients with first-line failure syndrome and associated mechanical metatarsalgia-producing deformities...
January 2017: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/28737013/anatomic-variations-of-neck-vessels-and-the-course-of-pediatric-internal-jugular-veins
#18
Kai-Ming Yuan, En-Ci Liu, Ping Li, Wang-Ning Shangguan, Jun Li, Qing-Quan Lian
BACKGROUND: Landmark-guided internal jugular vein cannulation is difficult for pediatric patients but useful, especially when ultrasound equipment is unavailable. Therefore, it is important to define the adjacent anatomic characteristics of the pediatric internal jugular vein. METHODS: In 210 children the course of the internal jugular vein, and common carotid and vertebral arteries was measured from the level of the cricoid cartilage to the supraclavicular area using ultrasound...
July 24, 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28734710/use-of-trabecular-bone-score-tbs-as-a-complementary-approach-to-dual-energy-x-ray-absorptiometry-dxa-for-fracture-risk-assessment-in-clinical-practice
#19
Enisa Shevroja, Olivier Lamy, Lynn Kohlmeier, Fjorda Koromani, Fernando Rivadeneira, Didier Hans
Osteoporosis is a common bone disease characterized by low bone mass and altered bone microarchitecture, resulting in decreased bone strength with an increased risk of fractures. In clinical practice, physicians can assess the risk of fracture for a patient based on several risk factors. Some such as age, weight, and history of fractures after 50 years of age, parental fracture, smoking status, and alcohol intake are incorporated into FRAX, an assessment tool that estimates the 10-year probability of hip fracture and major osteoporotic fractures based on the individual's risk factors profile...
July 19, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28733473/do-depression-and-anxiety-reduce-the-likelihood-of-remission-in-rheumatoid-arthritis-and-psoriatic-arthritis-data-from-the-prospective-multicentre-nor-dmard-study
#20
Brigitte Michelsen, Eirik Klami Kristianslund, Joseph Sexton, Hilde Berner Hammer, Karen Minde Fagerli, Elisabeth Lie, Ada Wierød, Synøve Kalstad, Erik Rødevand, Frode Krøll, Glenn Haugeberg, Tore K Kvien
OBJECTIVE: To investigate the predictive value of baseline depression/anxiety on the likelihood of achieving joint remission in rheumatoid arthritis (RA) and psoriatic arthritis (PsA) as well as the associations between baseline depression/anxiety and the components of the remission criteria at follow-up. METHODS: We included 1326 patients with RA and 728 patients with PsA from the prospective observational NOR-DMARD study starting first-time tumour necrosis factor inhibitors or methotrexate...
July 21, 2017: Annals of the Rheumatic Diseases
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