Ming Chen, Xiaowei Xia, Zhuang Kang, Zhinan Li, Jiamin Dai, Junyan Wu, Cai Chen, Yong Qiu, Tong Liu, Yanxi Liu, Ziyi Zhang, Qingni Shen, Sichu Tao, Zixin Deng, Ying Lin, Qinling Wei
This study aimed to identify neural biomarkers for schizophrenia (SZ) and bipolar disorder (BP) by analyzing multimodal neuroimaging. Utilizing data from structural magnetic resonance imaging (sMRI), diffusion tensor imaging (DTI), and resting-state functional magnetic resonance imaging (rs-fMRI), multiclass classification models were created for SZ, BP, and healthy controls (HC). A total of 113 participants (BP: 31, SZ: 39, and HC: 43) were recruited under strict enrollment control, from which 272, 200, and 1875 features were extracted from sMRI, DTI, and rs-fMRI data, respectively...
February 15, 2024: Journal of Psychiatric Research