keyword
https://read.qxmd.com/read/38652504/recommendations-for-pharmacogenetic-testing-in-clinical-practice-guidelines-in-the-us
#1
JOURNAL ARTICLE
Daniel L Hertz, Chad A Bousman, Howard L McLeod, Andrew A Monte, Deepak Voora, Lori A Orlando, Rustin D Crutchley, Benjamin Brown, Wrenda Teeple, Sara Rogers, Jai N Patel
DISCLAIMER: In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. PURPOSE: Pharmacogenetic testing can identify patients who may benefit from personalized drug treatment...
April 23, 2024: American Journal of Health-system Pharmacy: AJHP
https://read.qxmd.com/read/38650772/interest-in-rhinoplasty-and-awareness-of-postoperative-complications-among-female-high-school-students-in-taif-saudi-arabia
#2
JOURNAL ARTICLE
Muhanna A Alhusayni, Abrar A Alzahrani, Fahad M Alhomaidi, Raghad N Alotaibi, Liyan K Abu Rukbah, Ghadi F Alotaibi, Marwan F Alnofaie
Background and objective There has been a significant increase in rhinoplasty procedures in Saudi Arabia recently. Cultural factors, societal pressure, and a desire for beauty and self-improvement contribute to the growing interest in cosmetic procedures among the Saudi population. However, limited research has been conducted specifically focusing on the interest in rhinoplasty and the awareness of postoperative complications among female high school students. This study aimed to investigate the interest in rhinoplasty and awareness of postoperative complications among female high school students in Taif, Saudi Arabia...
March 2024: Curēus
https://read.qxmd.com/read/38649968/underreporting-of-implementation-strategies-and-barriers-in-physical-activity-interventions-for-young-people-at-risk-of-problematic-substance-use-a-brief-report
#3
JOURNAL ARTICLE
Lisa Klamert, Melinda Craike, Gillinder Bedi, Susan Kidd, Michaela C Pascoe, Alexandra G Parker
BACKGROUND: Several studies have assessed whether physical activity interventions can reduce substance use in young people at risk of problematic substance use. This report identifies and describes the reporting of implementation characteristics within published studies of physical activity interventions for young people at risk of problematic substance use and provides recommendations for future reporting. METHODS: Reported implementation strategies (including intervention manualization), barriers, implementation fidelity, and personnel acceptance were extracted from studies of physical activity interventions for young people aged 12-25 years at risk of problematic substance use that were included in a previous systematic review of intervention efficacy...
April 22, 2024: Implementation science communications
https://read.qxmd.com/read/38649855/implementation-processes-of-social-network-interventions-for-physical-activity-and-sedentary-behavior-among-children-and-adolescents-a-scoping-review
#4
JOURNAL ARTICLE
Jose Petro-Petro, Carlos Mario Arango-Paternina, Fredy Alonso Patiño-Villada, Jhon Fredy Ramirez-Villada, Ross C Brownson
BACKGROUND: The characteristics of the implementation process of interventions are essential for bridging the gap between research and practice. This scoping review aims to identify the implementation process of social network interventions (SNI) to address physical activity and sedentary behaviors in children and adolescents. METHODS: The scoping review was conducted adhering to the established guidelines. The search was carried out in the ERIC, EBSCO, EMBASE, SCOPUS, and Lilacs databases in April 2023...
April 22, 2024: BMC Public Health
https://read.qxmd.com/read/38648380/assessment-of-barriers-to-cancer-screening-and-interventions-implemented-to-overcome-these-barriers-in-27-latin-american-and-caribbean-countries
#5
JOURNAL ARTICLE
Isabel Mosquera, Clara B Barajas, Hannah Theriault, Sara Benitez Majano, Li Zhang, Mauricio Maza, Silvana Luciani, Andre L Carvalho, Partha Basu
There is a gap in the understanding of the barriers to cancer screening participation and complying with downstream management in the Community of Latin American and Caribbean states (CELAC). Our study aimed to assess barriers across the cancer screening pathway from the health system perspective, and interventions in place to improve screening in CELAC. A standardized tool was used to collect information on the barriers across the screening pathway through engagement with the health authorities of 27 member states of CELAC...
April 22, 2024: International Journal of Cancer. Journal International du Cancer
https://read.qxmd.com/read/38647417/an-analysis-of-chatgpt4-to-respond-to-glaucoma-related-questions
#6
JOURNAL ARTICLE
Suleyman Gokhan Kerci, Berna Sahan
PRECIS: In recent years, ChatGPT has been widely used as a source of information. In our study, it was revealed that ChatGPT gives accurate information about glaucoma. PURPOSE: We examined the knowledge of ChatGPT about glaucoma. PATIENTS AND METHODS: Frequently asked questions about glaucoma found on websites of ophthalmology associations and hospitals, and social media applications were assessed. Evidence-Based Recommendations in the European Glaucoma Society Terminology and Guidelines for Glaucoma 5th Edition were evaluated...
April 23, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38645423/hair-hormone-data-from-syrian-refugee-children-perspectives-from-a-two-year-longitudinal-study
#7
REVIEW
Andrew K May, Demelza Smeeth, Fiona McEwen, Patricia Moghames, Elie Karam, Michael J Rieder, Abdelbaset A Elzagallaai, Stan van Uum, Michael Pluess
For numerous issues of convenience and acceptability, hair hormone data have been increasingly incorporated in the field of war trauma and forced displacement, allowing retrospective examination of several biological metrics thought to covary with refugees' mental health. As a relatively new research method, however, there remain several complexities and uncertainties surrounding the use of hair hormones, from initial hair sampling to final statistical analysis, many of which are underappreciated in the extant literature, and restrict the potential utility of hair hormones...
May 2024: Comprehensive psychoneuroendocrinology
https://read.qxmd.com/read/38643738/optimal-probiotic-combinations-for-treating-nonalcoholic-fatty-liver-disease-a-systematic-review-and-network-meta-analysis
#8
JOURNAL ARTICLE
Yafang Yang, Ligang Yang, Jiale Wu, Jing Hu, Min Wan, Jindi Bie, Jiaxin Li, Da Pan, Guiju Sun, Chao Yang
BACKGROUND: Probiotic administration is a promising therapy for improving conditions in NAFLD patients. This network meta-analysis aimed to compare and estimate the relative effects of probiotic interventions and identify the optimal probiotic species for the treatment of NAFLD (Nonalcoholic fatty liver disease) patients. METHODS: The PubMed, Web of Science, Embase, and Cochrane databases were searched from inception to 29 January 2024 to identify RCTs that were published in English...
April 13, 2024: Clinical Nutrition
https://read.qxmd.com/read/38642406/automated-treatment-planning-for-whole-breast-irradiation-with-individualized-tangential-imrt-fields
#9
JOURNAL ARTICLE
Giulianne Rivelli Rodrigues Zaratim, Ricardo Gomes Dos Reis, Marcos Antônio Dos Santos, Nathalya Ala Yagi, Luis Felipe Oliveira E Silva
PURPOSES: This study aimed to develop and validate algorithms for automating intensity modulated radiation therapy (IMRT) planning in breast cancer patients, with a focus on patient anatomical characteristics. MATERIAL AND METHODS: We retrospectively selected 400 breast cancer patients without lymph node involvement for automated treatment planning. Automation was achieved using the Eclipse Scripting Application Programming Interface (ESAPI) integrated into the Eclipse Treatment Planning System...
April 20, 2024: Journal of Applied Clinical Medical Physics
https://read.qxmd.com/read/38642203/a-pilot-randomized-controlled-trial-of-an-online-intervention-for-hodgkin-lymphoma-survivors-to-increase-knowledge-about-late-effects-and-recommended-screening
#10
JOURNAL ARTICLE
Tara J Rick, Smitha Sagaram, Patricia I Jewett, Hee Yun Lee, Karim T Sadak, Lucie M Turcotte, Rachel I Vogel, Anne Blaes
BACKGROUND: Hodgkin lymphoma (HL) survivors who received chest radiotherapy are at risk for breast cancer and cardiovascular disease, but screening adherence is low. We assessed the acceptability/feasibility of a web-based educational intervention and its impact on knowledge of health risks and screening. METHODS: HL survivors were randomized to either an interactive online educational intervention or handouts only. Surveys were completed at baseline and 3 months post-intervention...
April 20, 2024: Journal of Cancer Survivorship: Research and Practice
https://read.qxmd.com/read/38641831/protocol-for-a-systematic-review-and-meta-analysis-on-janus-kinase-inhibitors-in-the-management-of-vitiligo
#11
JOURNAL ARTICLE
Shelly Pranić, Anika Pulumati, Dubravka Vuković
BACKGROUND: Vitiligo is a disease that affects people of all skin shades and can impact their quality of life. Reliable evidence on the effectiveness and adverse events associated with the recent use of Janus kinase (JAK) inhibitors to treat vitiligo is needed. This protocol for a systematic review and meta-analysis seeks to collect evidence from both randomized controlled trials (RCTs) and observational studies to determine the effectiveness and patient-centered outcomes concerning treatment with JAK inhibitors...
April 19, 2024: Systematic Reviews
https://read.qxmd.com/read/38641202/neuropathic-pain-evidence-based-recommendations
#12
JOURNAL ARTICLE
Xavier Moisset
Neuropathic pain continues to be a significant problem that lacks effective solutions for every single patient. In 2015, international guidelines (NeuPSIG) were published, while the French recommendations were updated in 2020. The purpose of this minireview is to provide an update on the process of developing evidence-based recommendations and explore potential changes to the current recommendations. Primary treatments for neuropathic pain include selective serotonin-norepinephrine reuptake inhibitors (SNRIs) such as duloxetine and venlafaxine, gabapentin, tricyclic antidepressants, as well as topical lidocaine and transcutaneous electrical nerve stimulation, which are specifically suggested for focal peripheral neuropathic pain...
April 17, 2024: La Presse Médicale
https://read.qxmd.com/read/38640102/evaluation-of-the-universal-salt-iodization-usi-surveillance-system-in-tanzania-2022
#13
JOURNAL ARTICLE
David Mahwera, Erick Killel, Ninael Jonas, Adam Hancy, Anna Zangira, Aika Lekey, Rose Msaki, Doris Katana, Rogath Kishimba, Debora Charwe, Fatma Abdallah, Geofrey Chiduo, Ray Masumo, Germana Leyna, Geofrey Mchau
BACKGROUND: The evaluation of surveillance systems has been recommended by the World Health Organization (WHO) to identify the performance and areas for improvement. Universal salt iodization (USI) as one of the surveillance systems in Tanzania needs periodic evaluation for its optimal function. This study aimed at evaluating the universal salt iodization (USI) surveillance system in Tanzania from January to December 2021 to find out if the system meets its intended objectives by evaluating its attributes as this was the first evaluation of the USI surveillance system since its establishment in 2010...
2024: PloS One
https://read.qxmd.com/read/38639166/how-seeking-transfer-often-fails-to-help-define-medically-inappropriate-treatment
#14
JOURNAL ARTICLE
Douglas B White, Thaddeus M Pope
On September 1, 2023, Texas made important revisions to it its decades-old statute granting legal safe harbor immunity to physicians who withhold or withdraw life-sustaining treatment over the objection of critically ill patients' surrogate decision-makers. However, lawmakers left untouched glaring flaws in a key safeguard for patients-the transfer option. The transfer option is ethically important because, when no hospital is willing to accept the patient in transfer, that fact is taken as strong evidence that the surrogates' treatment requests fall outside accepted medical practice...
March 2024: Hastings Center Report
https://read.qxmd.com/read/38638045/a-day-saved-is-a-life-saved-direct-antimicrobial-susceptibility-testing-from-positively-flagged-blood-culture-bottles-and-their-concordance-with-the-routine-method
#15
JOURNAL ARTICLE
Alisha Aggarwal, Kumar S Abhishek, Vibhor Tak, Sukanya Mehrotra, Venkat Goutham Nag, Vidhi Jain
BACKGROUND: Sepsis is a major health problem worldwide and is associated with high morbidity and mortality with every hour delay in initiation of therapy. A conventional method of blood culture and Antimicrobial Susceptibility Testing (AST) takes around 48-72 hours. Empirical antibiotics need to be administered until the sensitivity report is made available. It has been estimated that 20-50% of the empirical antibiotics are inappropriate, resulting in prolonged hospital stays, adverse effects, and emergence of drug resistance...
April 17, 2024: Infectious Disorders Drug Targets
https://read.qxmd.com/read/38637977/facilitators-barriers-and-strategies-of-communication-in-malaysian-school-age-children-with-non-syndromic-cleft-lip-and-palate-results-of-in-depth-online-qualitative-interviews
#16
JOURNAL ARTICLE
M S Yusof, H M Ibrahim, T Bressmann, A M Hasbi
This study explores the perceptions of facilitators, barriers to communication and strategies in Malaysian school-aged children with non-syndromic cleft lip and palate (CL/P), parents, and teachers. Fourteen children with non-syndromic CL/P aged 7 to 12 years, their parents ( n  = 16), and their teachers ( n  = 10) were recruited via purposive sampling. Participants were selected based on resilience scores (RS-10; (Wagnild, 2015) distinguishing low (<34) from high resilience (35-40) (Wagnild, 2015)...
April 18, 2024: Clinical Linguistics & Phonetics
https://read.qxmd.com/read/38637806/perspectives-from-patients-with-chronic-lung-disease-on-a-telehealth-facilitated-integrated-palliative-care-model-a-qualitative-content-analysis-study
#17
JOURNAL ARTICLE
Jeannette Kates, Carrie Tompkins Stricker, Kristin L Rising, Alexzandra T Gentsch, Ellen Solomon, Victoria Powers, Venise J Salcedo, Brooke Worster
BACKGROUND: Chronic lung disease affects nearly 37 million Americans and often results in significant quality of life impairment and healthcare burden. Despite guidelines calling for palliative care (PC) integration into pulmonary care as a vital part of chronic lung disease management, existing PC models have limited access and lack scalability. Use of telehealth to provide PC offers a potential solution to these barriers. This study explored perceptions of patients with chronic lung disease regarding a telehealth integrated palliative care (TIPC) model, with plans to use findings to inform development of an intervention protocol for future testing...
April 18, 2024: BMC Palliative Care
https://read.qxmd.com/read/38636671/a-narrative-review-of-global-and-national-physical-activity-and-sedentary-behaviour-guidelines-development-processes-the-guidelines-standards-gus-project
#18
JOURNAL ARTICLE
Karen Milton, Coral L Hanson, Alice Pearsons, Roger Chou, Emmanuel Stamatakis
BACKGROUND: Clinical and public health guidelines serve to direct clinical practice and policy, based on the best available evidence. The World Health Organization (WHO) and national health bodies of many countries have released physical activity and sedentary behaviour guidelines. Despite significant overlap in the body of evidence reviewed, the guidelines differ across jurisdictions. This study aimed to review the processes used to develop global and national physical activity and sedentary behaviour guidelines and examine the extent to which they conform with a recommended methodological standard for the development of guidelines...
April 16, 2024: Preventive Medicine
https://read.qxmd.com/read/38636358/blended-care-in-psychosis-a-systematic-review
#19
REVIEW
Mayan Cohen, David Roe, Tomer Savir, Amit Baumel
Blended-care, a psychosocial intervention combining traditional, face-to-face therapy with digital mental health tools, has shown potential for improving therapeutic processes, fostering patient engagement, and augmenting clinical outcomes. This systematic review aimed to evaluate the development and effectiveness of blended-care interventions tailored for adults diagnosed with schizophrenia-spectrum disorders or other conditions with psychotic features. Our search strategy spanned three electronic databases (PsycINFO, Web of Science, and PubMed) in accordance with the reporting guidelines outlined by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses...
April 17, 2024: Schizophrenia Research
https://read.qxmd.com/read/38635776/gender-health-gaps-in-guideline-based-inpatient-cardiovascular-medical-and-nursing-care-and-implementation-strategies-to-reduce-the-gap-heartgap-a-mixed-methods-study-protocol
#20
JOURNAL ARTICLE
Sophia Sgraja, Judith Mollenhauer, Martina Kloepfer, Ute Seeland, Clarissa Kurscheid, Volker Amelung
BACKGROUND: A growing body of evidence has demonstrated that a gender-sensitive approach to healthcare is needed in all areas of medicine. Although medical and nursing guidelines include gender-sensitive care (GSC+) recommendations, the level of implementation in health care practice is unknown. This study aims to examine the current level of implementation and acceptance of GSC+ among physicians and nurses and to identify potential gaps between guidelines and practice and barriers and facilitators of GSC+ implementation, taking the perceptions of all relevant stakeholders into account...
2024: PloS One
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