Michael T Hawkes, Alastair McAlpine, Michelle Barton, Adrianna Ranger, Archana Balamohan, H Dele Davies, Gwenn Skar, Marie-Astrid Lefebvre, Ahmed Almadani, Dolores Freire, Nicole Le Saux, Jennifer Bowes, Jocelyn A Srigley, Patrick Passarelli, John Bradley, Sarah Khan, Rupeena Purewal, Isabelle Viel-Thériault, Joan L Robinson
OBJECTIVE: Cerebrospinal fluid (CSF) white blood cell (WBC) count, neutrophil percentage, protein concentration, and glucose level are typically measured at diagnosis and serially during the treatment of CSF shunt infections. The objective of this retrospective cohort study was to describe the longitudinal profile of CSF parameters in children with CSF shunt infections and assess their association with treatment and outcome. METHODS: Participants were children treated at 11 tertiary pediatric hospitals in Canada and the United States for CSF shunt infection, from July 1, 2013, through June 30, 2019, with hardware removal, external ventricular drain placement, intravenous antibiotics, and subsequent permanent shunt reinsertion...
October 13, 2023: Journal of Neurosurgery. Pediatrics