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JOURNAL ARTICLE
Asaf Lebel, Efrat Ben Shalom, Rozan Mokatern, Raphael Halevy, Yoav Zehavi, Daniela Magen
BACKGROUND AND OBJECTIVE: Apparent mineralocorticoid excess (AME) syndrome is an ultra-rare autosomal-recessive tubulopathy, caused by mutations in HSD11B2, leading to excessive activation of the kidney mineralocorticoid receptor, and characterized by early-onset low-renin hypertension, hypokalemia, and risk of chronic kidney disease (CKD). To date, most reports included few patients, and none described patients from Israel. We aimed to describe AME patients from Israel and to review the relevant literature...
April 23, 2024: European Journal of Endocrinology
#2
JOURNAL ARTICLE
Jian-Jiun Chen, Shih-Hsin Hung, Jia-You Liou, Wen-Chieh Chang, Kuei-Hsiang Hsu, Yu-Pin Su, Fang-Yao Chiu, Ming-Fai Cheng
PURPOSE: Periprosthetic femoral fractures (PPFs) around the hip are challenging complications in orthopaedic surgery, particularly Vancouver type B2 (VTB2) fractures. The surgical management of these fractures is crucial and depends on various factors. Cementless short taper stem with plate osteosynthesis is an alternative surgical technique. This study aims to compare the outcomes of this surgical technique with revision arthroplasty (RA) with long stem in the treatment of VTB2 PPFs...
April 23, 2024: International Orthopaedics
#3
JOURNAL ARTICLE
Darrick Vatterrodt, Janelle Lee, Dooil Ho, Craig Stevig, Siu-Kei Chow
UNLABELLED: The use of molecular identification panels has advanced the diagnosis for blood stream infections with fast turnaround time and high accuracy. Yet, this technology cannot completely replace conventional blood culture and standardized antibiotic susceptibility testing (AST) given its limitations and occasional false results. Here we present two cases of bacteremia caused by Kluyvera . Its identification and antibiotic resistance were at least partially mispresented by blood culture molecular identification panels on ePlex, Verigene, and Biofire...
April 23, 2024: Microbiology Spectrum
#4
JOURNAL ARTICLE
Simona Sestito, Lucia Brodosi, Stefania Ferraro, Rosa Carella, Donatella De Giovanni, Dorina Mita, Michele Moretti, Maria Teresa Moricca, Daniela Concolino, Albina Tummolo
Background: Maternal phenylketonuria (mPKU) is a pathologic condition occurring in the fetus of a mother with PKU that is caused by prolonged elevated intrauterine blood phenylalanine (Phe) levels, which can lead to congenital abnormalities and mental retardation of newborns. Management of PKU during pregnancy can be challenging as protein substitutes may exacerbate nausea, vomiting, and gastrointestinal symptoms. Aim: To report the successful management of four PKU pregnant women. Methods: The patients were administered with prolonged-release amino acid supplementation and were recommended to follow a strict diet...
April 23, 2024: Nutrition and Health
#5
JOURNAL ARTICLE
H A Mensink, A Desai, M Cvetkovic, M Davidson, A Hoskote, M O'Callaghan, T Thiruchelvam, P P Roeleveld
Extracorporeal Cardiopulmonary Resuscitation (ECPR) has potential benefits compared to conventional Cardiopulmonary Resuscitation (CCPR) in children. Although no randomised trials for paediatric ECPR have been conducted, there is extensive literature on survival, neurological outcome and risk factors for survival. Based on current literature and guidelines, we suggest recommendations for deployment of paediatric ECPR emphasising the requirement for protocols, training, and timely intervention to enhance patient outcomes...
April 2024: Perfusion
#6
REVIEW
Costanza Rossi, Alessandro Buizza, Giuseppe Alessio, Massimiliano Borselli, Andrea Taloni, Adriano Carnevali, Giovanna Carnovale Scalzo, Andrea Lucisano, Vincenzo Scorcia, Giuseppe Giannaccare
Ocular complications can occur in up to 90% of patients with blood malignancies. Such complications range from direct infiltration to local hemostatic imbalance and treatment-related toxicity. This narrative review is based on a systematic computerized search of the literature conducted until January 2024 and examines the common ocular complications associated with blood cancers. Ocular complications from primary disease include mass effects from ocular adnexal lymphomas and intraocular lymphomas, with B-cell lymphomas accounting for 95% of primary ocular presentations...
March 28, 2024: Hematology Reports
#7
JOURNAL ARTICLE
Jeanne-Marie Perotin, Lisa Gauquelin, Nicolas Just, Gilles Devouassoux, Cécile Chenivesse, Arnaud Bourdin, Gilles Garcia, Christel Saint Raymond, Amel Boudjemaa, Philippe Bonniaud, Pascal Chanez, Cindy Barnig, Antoine Beurnier, Cyril Maurer, Nathalie Freymond, Toufik Didi, Colas Tcherakian, Maud Russier, Mélanie Drucbert, Sylvie Guillo, Candice Estellat, Camille Taillé
BACKGROUND: The French RAMSES study is an observational prospective multicentre real-life cohort including severe asthmatic subjects. The objective of the study was to compare the characteristics of patients, in terms of phenotype and asthma care trajectories, between those managed by tertiary referral centres (TRCs) or secondary care centres (SCCs). METHODS: Patients were prospectively recruited and enrolled for a 5-year follow-up. Patients' characteristics were analysed at inclusion and compared between TRCs and SCCs...
March 2024: ERJ Open Research
#8
Shun Nishino, Masanori Nishimura, Yujiro Asada, Atsushi Yamashita, Yoshisato Shibata
BACKGROUND: Aortic regurgitation (AR) associated with detachment of the aortic valve commissure is extremely rare. We present a case of progressively worsening severe chronic AR due to detachment of the aortic valve commissure during hospitalization that was confirmed with multimodality imaging. CASE SUMMARY: A 50-year-old male with Marfan syndrome visited our hospital to receive treatment for cholelithiasis. Pre-operative examination revealed severe AR and aortic root aneurysm...
April 2024: European Heart Journal. Case Reports
#9
Abdullah Alhelal, Ali M Assiri, Anas A Alqarni, Abdulrazak Tamim, Yazeed M Mohammad
Cerebral palsy (CP) is a neurodevelopmental disorder that affects motor function and is often accompanied by secondary musculoskeletal issues. Severe scoliosis, a lateral curvature of the spine over 40 degrees, poses a significant challenge for individuals with CP, impacting their mobility and overall well-being. While the association between scoliosis and gastrointestinal complications is acknowledged, the occurrence of colonic volvulus with necrosis in the context of CP and severe scoliosis is rare and complex...
March 2024: Curēus
#10
Masahito Katsuki, Taiki Fukushima, Tetsuya Goto, Yoshiki Hanaoka, Naomichi Wada, Takuya Nakamura, Shiori Sasaki, Tetsuyoshi Horiuchi
Aneurysmal subarachnoid hemorrhage (SAH) is a critical condition associated with high mortality rates. Hypertension is a significant risk factor for SAH development and recurrence following coil embolization for a ruptured aneurysm. While reduction of salt consumption is crucial for managing hypertension, it often compromises food taste. Anodal electrical taste stimulation (ETS) has been proposed to enhance taste perception without altering salt content. We present the case of a 69-year-old female SAH patient with a ruptured aneurysm at the anterior communicating artery who underwent coil embolization and in whom we tested ETS's efficacy in enhancing the salt taste perception on day 42 after the procedure...
March 2024: Curēus
#11
JOURNAL ARTICLE
Andre E Manov, Nathan Holt, Esar Dini, Ranier Rivera, Ashrita Donepudi, Rakahn Haddadin, Kyle Mefferd, Inam Qadir
We conducted a retrospective observational cohort study between 2020 and 2023 in 26 patients with type 1 and type 2 diabetes mellitus (DM) who were using 3-4 injections per day of insulin and were monitored by continuous glucose monitoring (CGM). The goal of this retrospective observational cohort study is to compare these two metrics in an internal medicine community primary care residency clinic. We used CGM devices, Dexcom G6 and G7, and Freestyle Libre 3. The goal was to compare the patient's hemoglobin A1c (HbA1c) taken during their clinic visit by phlebotomy as a marker for diabetic control with an estimated HbA1c glucose management indicator (GMI) derived from the 30-day CGM readings...
March 2024: Curēus
#12
REVIEW
Huihui Yu, Jingyi Diao, Jiajia Fei, Xingxing Wang, Dan Li, Zongzhi Yin
BACKGROUND: Cesarean hysterectomy is a dominant and effective approach during delivery in patients with placenta accreta spectrum (PAS). However, as hysterectomy results in a loss of fertility, conservative management is an alternative approach. However, management selection may be affected by a country's overall economic level. Thus the preferred treatment for PAS generates controversy in middle-income countries. OBJECTIVES: We aimed to compare conservative management and cesarean hysterectomy for managing PAS in middle-income countries...
April 22, 2024: International Journal of Gynaecology and Obstetrics
#13
Justin E Juskewitch, Lynne Briggs, Jenna Khan, Patrick C Mathias, Terri S Coyle, Vicki L Courson, James T Hansen, Nageswar Madde, Mandy F O'Leary, Hamilton C Tsang
BACKGROUND: With the widespread adoption of Blood Establishment Computer Systems and other Blood Collection and Transfusion Service (BCTS) clinical information systems (CIS), electronic blood donor, product, and patient data are now routinely required for clinical, regulatory, operational, and quality needs. That data are often not readily accessible for such secondary use within CIS databases, particularly for applications with significant data availability requirements such as machine learning and artificial intelligence...
April 22, 2024: Transfusion
#14
JOURNAL ARTICLE
Bekim Ademi, Luan Jaha, Isa Haxhiu, Xhevdet Çuni, Afrim Tahiri, Jetmir Gashi, Adhurim Koshi, Art Jaha
BACKGROUND: Renal cell carcinomas are the most common form of kidney cancer in adults. In addition to metastasizing in lungs, soft tissues, bones, and the liver, it also spreads locally. In 2-10% of patients, it causes a thrombus in the renal or inferior vena cava vein; in 1% of patients thrombus reaches the right atrium. Surgery is the only curative option, particularly for locally advanced disease. Despite the advancements in laparoscopic, robotic and endovascular techniques, for this group of patients, open surgery continues to be among the best options...
April 23, 2024: Journal of Medical Case Reports
#15
JOURNAL ARTICLE
Jun Nagayama, Takeo Sato, Ishida Takanori, Koga Kouji, Nakamura Mitsunobu
BACKGROUND: Necrotising fasciitis (NF) is a life-threatening soft-tissue infection that rapidly destroys the epidermis, subcutaneous tissue, and fascia. Despite their low virulence, Lactobacillus spp. can cause NF, and because of its rare incidence, there is limited information about its molecular and clinicopathological characteristics. We report a rare case of NF in a patient with type 2 diabetes mellitus diagnosed on admission and severe obesity due to infection with two types of Lactobacillus spp...
April 22, 2024: BMC Infectious Diseases
#16
JOURNAL ARTICLE
Jin-Zhu Wang, Ding Yuan, Xiang-Hong Yang, Chang-Hua Sun, Lin-Lin Hou, Yan Zhang, Hong-Xiang Xie, Yan-Xia Gao
BACKGROUND: Severe acute respiratory infection (SARI), a significant global health concern, imposes a substantial disease burden. In China, there is inadequate data concerning the monitoring of respiratory pathogens, particularly bacteria, among patients with SARI. Therefore, this study aims to delineate the demographic, epidemiological, and aetiological characteristics of hospitalised SARI patients in Central China between 2018 and 2020. METHODS: Eligible patients with SARI admitted to the First Affiliated Hospital of Zhengzhou University between 1 January 2018 and 31 December 2020 were included in this retrospective study...
April 22, 2024: BMC Infectious Diseases
#17
REVIEW
Jacopo Proietti, Geraldine B Boylan, Brian H Walsh
Early induced therapeutic hypothermia represents the cornerstone treatment in neonates with probable hypoxic-ischemic encephalopathy. The selection of patients for treatment usually involves meeting criteria indicating evidence of perinatal hypoxia-ischemia and the presence of moderate or severe encephalopathy. In this review, we highlight the variability that exists between some of the different regional and national eligibility guidelines. Determining the potential presence of perinatal hypoxia-ischemia may require either one, two or three signs amongst history of acute perinatal event, prolonged resuscitation at delivery, abnormal blood gases and low Apgar score, with a range of cutoff values...
April 22, 2024: Pediatric Research
#18
JOURNAL ARTICLE
Ellen Daily Stephen, Sven Wang, Manali Shah, Anandu Dileep, Shannon Manz, Niki Mirhosseini, Mahboobeh Mahdavinia
BACKGROUND: Atopic dermatitis (AD) is a known risk factor for the development of food allergy. Prior work has suggested disparities in diagnosis/management of food allergy in urban populations. OBJECTIVE: We aimed to determine whether socioeconomic conditions, as measured by the Area Deprivation Index (ADI) and insurance status, or racial/ethnic self-identity were associated with risk of food allergy diagnosis (DFA), evaluation by an allergist, or objective food allergy testing among high-risk children with atopic dermatitis...
April 20, 2024: Annals of Allergy, Asthma & Immunology
#19
JOURNAL ARTICLE
Abel A Pavía-López, José A Magaña-Serrano, José A Cigarroa-López, Adolfo Chávez-Mendoza, José L Mayorga-Butrón, Diego Araiza-Garaygordobil, Juan B Ivey-Miranda, Gustavo F Méndez-Machado, Héctor González-Godínez, Luisa F Aguilera-Mora, Antonio Jordán-Ríos, Luis Olmos-Domínguez, Marcos J Olalde-Román, Emma M Miranda-Malpica, Zuilma Vázquez-Ortiz, Jorge Rayo-Chávez, Alexandra A Mendoza, Manlio F Márquez-Murillo, Sergio A Chávez-Leal, Amada Álvarez-San Gabriel, Marissa A Silva-García, Alex D Pacheco-Bouthiller, Jorge A Aldrete-Velazco, Carlos A Guizar-Sánchez, Efraín Gaxiola-López, Arturo Guerra-López, Lourdes Figueiras-Graillet, Gustavo Sánchez-Miranda, Genaro H Mendoza-Zavala, Moisés Aceves-García, Adolfo Chávez-Negrete, Marisol Arroyo-Hernández, Bertha B Montaño-Velázquez, Luis F Romero-Moreno, María M Baquero-Hoyos, Liliana Velasco-Hidalgo, Ana L Rodríguez-Lozano, Nancy E Aguilar-Gómez, Mario Rodríguez-Vega, Jorge E Cossío-Aranda
Chronic heart failure continues to be one of the main causes of impairment in the functioning and quality of life of people who suffer from it, as well as one of the main causes of mortality in our country and around the world. Mexico has a high prevalence of risk factors for developing heart failure, such as high blood pressure, diabetes, and obesity, which makes it essential to have an evidence-based document that provides recommendations to health professionals involved in the diagnosis and treatment of these patients...
2024: Archivos de Cardiología de México
#20
JOURNAL ARTICLE
Ansa Anam, Chang Liu, Louis Tong, Yu-Chi Liu
Blood-derived preparations, including autologous or allogenic serum, umbilical cord serum/plasma, and platelet-rich plasma eye drops, contain various growth factors, cytokines, and immunoglobulins that resemble natural tears. These components play important roles in corneal cell migration, proliferation, and wound healing. Blood-derived eye drops have demonstrated clinical effectiveness across a spectrum of ocular surface conditions, encompassing dry eye disease, Sjögren's syndrome, graft-versus-host disease, and neuropathic corneal pain (NCP)...
April 22, 2024: Journal of Ocular Pharmacology and Therapeutics
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