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https://www.readbyqxmd.com/read/28226878/design-and-preliminary-evaluation-of-a-wearable-device-for-mass-screening-of-sleep-apnea
#1
Rohan S Puri, Athanasios G Athanassiadis, Niharika Gill, Sai Sri Sathya, Geetanjali Rathod, Akshat Wahi, Guy Satat, Maulik Majmudar, Pratik Shah, Rohan S Puri, Athanasios G Athanassiadis, Niharika Gill, Sai Sri Sathya, Geetanjali Rathod, Akshat Wahi, Guy Satat, Maulik Majmudar, Pratik Shah, Athanasios G Athanassiadis, Maulik Majmudar, Geetanjali Rathod, Sai Sri Sathya, Akshat Wahi, Niharika Gill, Pratik Shah, Rohan S Puri, Guy Satat
Between 7-18 million Americans suffer from sleep disordered breathing (SDB), including those who suffer from obstructive sleep apnea (OSA). Despite this high prevalence and burden of OSA, existing diagnostic techniques remain impractical for widespread screening. In this study, we introduce a new model for OSA screening and describe an at-home wearable sleep mask (named ARAM) that can robustly track the wearers' sleep patterns. This monitoring is achieved using select sensors that enable screening and monitoring in a form-factor that can be easily self-instrumented...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225162/mandibular-position-and-movements-suitability-for-diagnosis-of-sleep-apnoea
#2
Jean-Benoit Martinot, Jean-Christian Borel, Valérie Cuthbert, Hervé Jean-Pierre Guénard, Stéphane Denison, Philip E Silkoff, David Gozal, Jean-Louis Pepin
BACKGROUND AND OBJECTIVE: Mandibular movements (MMs) and position during sleep reflect respiratory efforts related to increases in upper airway resistance and micro-arousals. The study objective was to assess whether MM identifies sleep-disordered breathing (SDB) in patients with moderate to high pre-test probability. METHODS: This was a prospective study of 87 consecutive patients referred for an in-laboratory sleep test. Magnetometer-derived MM signals were incorporated into standard polysomnography (PSG)...
November 6, 2016: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28224726/a%C3%A4-rway-and-sleep-d%C3%A4-sorders-%C3%A4-n-pat%C3%A4-ents-w%C3%A4-th-acromegaly
#3
Onur Turan, Barış Akıncı, Ahmet Omer Ikız, Oya Itıl, Ibrahim Oztura, Emel Ada, Bahri Akdenız, Serkan Yener, Murat Kaya, Arzu Gedık, Abdurrahman Comlekcı
INTRODUCTION-OBJECTIVE: Acromegaly is a multisystemic disorder caused by excessive secretion of growth hormone (GH). Sleep-disordered breathing (SDB) such as sleep apnea syndrome (SAS) may occur in acromegaly. The aim of study was to assess the presence of sleep disorders and evaluate the systemic complications on respiratory, cardiovascular and upper airway systems in acromegalic patients. METHODS: The study group consisted of 30 acromegaly outpatients. GH and insulin-like growth factor 1 (IGF-1) measurements were obtained; body pletysmography, arterial blood gas analysis,tissue-doppler imaging,echocardiography,polysomnography,otorhinolaryngologic examination and head-neck computed tomography were performed...
February 22, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28224648/impacts-of-disease-severity-on-postoperative-complications-in-children-with-sleep-disordered-breathing
#4
Kun-Tai Kang, I-Sheng Chang, Chia-Chen Tseng, Wen-Chin Weng, Tzu-Yu Hsiao, Pei-Lin Lee, Wei-Chung Hsu
OBJECTIVES/HYPOTHESIS: To investigate the effects of diseases severity on postoperative complications following adenotonsillectomy (T&A) in children with sleep-disordered breathing (SDB). STUDY DESIGN: Retrospective study. METHODS: Children aged <18 years were enrolled and underwent T&A for treating SDB. Polysomnography was used to classify the disease severity: primary snoring (apnea-hypopnea index [AHI] <1), mild (AHI = 1-5), moderate (AHI = 5-10), and severe obstructive sleep apnea [OSA] (AHI ≥10)...
February 22, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28216558/application-of-passive-sampling-to-characterise-the-fish-exometabolome
#5
Mark R Viant, Jessica Elphinstone Davis, Cathleen Duffy, Jasper Engel, Craig Stenton, Marion Sebire, Ioanna Katsiadaki
The endogenous metabolites excreted by organisms into their surrounding environment, termed the exometabolome, are important for many processes including chemical communication. In fish biology, such metabolites are also known to be informative markers of physiological status. While metabolomics is increasingly used to investigate the endogenous biochemistry of organisms, no non-targeted studies of the metabolic complexity of fish exometabolomes have been reported to date. In environmental chemistry, Chemcatcher(®) (Portsmouth, UK) passive samplers have been developed to sample for micro-pollutants in water...
February 14, 2017: Metabolites
https://www.readbyqxmd.com/read/28215238/sleep-disordered-breathing-in-children-with-cerebral-palsy
#6
Engin Koyuncu, Mustafa H Türkkani, Fatma G Sarikaya, Neşe Özgirgin
OBJECTIVES: The purpose of this study was to investigate the frequency of Sleep Disordered Breathing (SDB) in children with Cerebral Palsy (CP), and determine whether a relationship between SDB and age, gender, weight status, type of CP, motor function level, and spasticity can be established. METHODS: The study included 94 children with CP and 94 healthy children with normal development, between the ages two and 18. SDB was assessed using the Sleep-Related Breathing Disorder (SRBD) scale of the Pediatric Sleep Questionnaire (PSQ)...
February 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28213507/effect-of-sleep-disordered-breathing-on-appropriate-implantable-cardioverter-defibrillator-therapy-in-patients-with-heart-failure-a-systematic-review-and-meta-analysis
#7
Younghoon Kwon, Ryan J Koene, Osung Kwon, Jessica V Kealhofer, Selcuk Adabag, Sue Duval
BACKGROUND: Patients with heart failure and reduced ejection fraction are at increased risk of malignant ventricular arrhythmias. Implantable cardioverter-defibrillator (ICD) is recommended to prevent sudden cardiac death in some of these patients. Sleep-disordered breathing (SDB) is highly prevalent in this population and may impact arrhythmogenicity. We performed a systematic review and meta-analysis of prospective studies that assessed the impact of SDB on ICD therapy. METHODS AND RESULTS: Relevant prospective studies were identified in the Ovid MEDLINE, EMBASE, and Google Scholar databases...
February 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/28211952/long-term-experience-with-first-generation-implantable-neurostimulation-device-in-central-sleep-apnea-treatment
#8
Henrik Fox, Thomas Bitter, Dieter Horstkotte, Olaf Oldenburg, Klaus-Jürgen Gutleben
BACKGROUND: Sleep-disordered breathing (SDB) and Cheyne-Stokes respiration (CSR) are associated with shorter survival in patients with heart failure (HF). A novel treatment method for this patient group is unilateral phrenic nerve stimulation by the remedē® system, a transvenously implantable neurostimulation device, which has recently been studied in a large randomized, controlled trial. Previous literature has shown efficacy and safety of the treatment with this first-generation device, but hardly any data is available on long-term clinical parameters, the remedē® device's battery lifetime, device exchangeability, lead position stability, surgical accessibility and manageability...
February 17, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28206895/evaluation-of-current-screening-and-treatment-patterns-for-pediatric-obstructive-sleep-apnea-among-practicing-pediatric-dentists-in-the-united-states-a-pilot-study
#9
John Keating, Jae Hyun Park
PURPOSE: The purpose of this study was to provide an evaluation of educational experience, screening, referral, and treatment patterns by pediatric dentists in the United States with regards to obstructive sleep apnea (OSA) and sleep-disordered breathing (SDB). METHODS: A twenty-six question, multiple choice, electronic survey was developed using SurveyMonkey software. It was distributed to the 6,017 active American Academy of Pediatric Dentistry (AAPD) members, garnering a response rate of 7...
October 15, 2016: Pediatric Dentistry
https://www.readbyqxmd.com/read/28197218/polysomnographic-findings-in-infants-with-pierre-robin-sequence
#10
Abdullah Khayat, Saadoun Bin-Hassan, Suhail Al-Saleh
INTRODUCTION: Pierre Robin sequence (PRS) is characterized by the triad of micrognathia, glossoptosis, and upper airway obstruction. It is commonly associated with the secondary cleft palate. Infants with PRS commonly have sleep-disordered breathing (SDB); including obstructive sleep apnea (OSA) as well as central sleep breathing abnormalities that are present from infancy. AIM OF THE STUDY: Evaluate the prevalence and severity of SDB in infants with PRS using polysomnography (PSG)...
January 2017: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/28193298/does-drug-induced-sleep-endoscopy-change-the-surgical-decision-in-surgically-na%C3%A3-ve-non-syndromic-children-with-snoring-sleep-disordered-breathing-from-the-standard-adenotonsillectomy-a-retrospective-cohort-study
#11
Malak Jamal Gazzaz, André Isaac, Scott Anderson, Noura Alsufyani, Yaser Alrajhi, Hamdy El-Hakim
BACKGROUND: Adenotonsillectomy is the most commonly performed operation for pediatric snoring/sleep disordered breathing (S/SDB). However, 20-40% of patients will fail to improve. Drug-induced sleep endoscopy (DISE) may provide a more individualized surgical plan and limit unsuccessful surgeries. The aim of this study was to assess the impact of DISE on surgical decision-making in surgically naïve children with S/SDB. METHODS: A retrospective observational cohort study was undertaken at the Stollery Children's Hospital...
February 13, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28178694/resolution-of-cheyne-stokes-respiration-after-treatment-of-heart-failure-with-sacubitril-valsartan-a-first-case-report
#12
Henrik Fox, Thomas Bitter, Dieter Horstkotte, Olaf Oldenburg
Sleep-disordered breathing (SDB) is highly prevalent in patients with heart failure (HF), and is known to be associated with a worse prognosis. The severity of central sleep apnea is thought to mirror cardiac dysfunction. The novel angiotensin receptor-neprilysin inhibitor (ARNi) sacubitril has been shown to improve HF, but a relationship between treatment with ARNi and the severity of SDB has not yet been investigated. We report the case of a 71-year-old male with HF and SDB. Treatment with sacubitril/valsartan was associated with improved cardiac function, as shown by a reduction in the level of N-terminal prohormone of brain natriuretic peptide from 3,249 to 1,720 pg/mL, and an improvement in left-ventricular ejection fraction from 30 to 35%...
February 9, 2017: Cardiology
https://www.readbyqxmd.com/read/28167000/urine-cysteinyl-leukotriene-levels-in-children-with-sleep-disordered-breathing-before-and-after-adenotonsillectomy
#13
A Satdhabudha, P Sritipsukho, S Manochantr, W Chanvimalueng, U Chaumrattanakul, P Chaumphol
OBJECTIVES: Obstructive sleep apnea (OSA) is a common problem in children and is associated with increased cardiovascular, neurobehavioral and somatic growth consequences. Cysteinyl leukotrienes (CysLTs) play a major role with local and systemic relations to the pathophysiology of OSA. The level of CysLTs in urine, blood, exhaled breath and adenotonsillar tissue of OSA children are increased. However it remains unclear whether inflammatory marker levels are alleviated after adenotonsillectomy...
March 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28155104/estimating-sleep-time-from-non-eeg-based-psg-signals-in-the-diagnosis-of-sleep-disordered-breathing
#14
M B Norman, C E Sullivan
PURPOSE: The purpose of this study was to use non-EEG PSG signals to estimate TST in order to diagnose SDB with a greater sensitivity than type 3 device methodology that relies on TRT. METHODS: Movement patterns were obtained from the thoracoabdominal signals of adult PSG recordings (n = 60) in the laboratory and the home. Parameters obtained allowed, with 95% certainty, identification of sleep and wake based on the duration of movements and quiescent time (Qd)...
February 3, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28153218/sleep-related-intermittent-hypoxia-is-associated-with-decreased-psychomotor-vigilance-in-japanese-community-residents
#15
Sakurako Tanno, Takeshi Tanigawa, Koutatsu Maruyama, Eri Eguchi, Takashi Abe, Isao Saito
BACKGROUND: Sleep disordered breathing (SDB) is associated with decreased psychomotor vigilance (hereafter "vigilance") in clinical settings, but this association has yet to be confirmed in the general population. The aim of this study is to determine the associations between SDB and vigilance in a large sample of community-based participants. METHODS: The study sample consisted of 1508 community-dwelling Japanese persons (age: 30-79 years, women: 62.7%, mean body mass index [BMI]: 23...
January 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28153212/nocturnal-intermittent-hypoxia-and-short-sleep-duration-are-independently-associated-with-elevated-c-reactive-protein-levels-in-patients-with-coronary-artery-disease
#16
Ryoma Fukuoka, Takashi Kohno, Shun Kohsaka, Ryo Yanagisawa, Takashi Kawakami, Kentaro Hayashida, Hideaki Kanazawa, Shinsuke Yuasa, Yuichiro Maekawa, Motoaki Sano, Keiichi Fukuda
BACKGROUND: Sleep-disordered breathing (SDB) or short sleep duration and coronary artery disease (CAD) are related, yet, the prevalence of SDB and short sleep duration as well as their mechanism remain unknown. Enhanced vascular inflammation is also implicated as one of the pathophysiologic mechanisms in CAD. The aims of this study were to evaluate the prevalence of patients with SDB and short sleep duration, and to examine their relationship with serum C-reactive protein (CRP) level in CAD patients...
January 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28143688/sleep-apnea-state-of-the-art
#17
REVIEW
Martin R Cowie
Many patient with, or at risk of, cardiovascular disease have sleep disordered breathing (SDB), which can be either obstructive (with intermittent collapse of the upper airway) or central (episodic loss of respiratory drive). SDB is associated with sleep disturbance, hypoxemia, hemodynamic changes, and sympathetic activation. Such patients have a worse prognosis than those without SDB. Mask-based therapies of positive airway pressure targeted at SDB can improve measures of sleep quality and partially normalize the sleep and respiratory physiology, but recent randomized trials of cardiovascular outcomes in SDB have either been neutral (obstructive sleep apnea) or suggested the possibility of harm, likely from increased sudden death, in central sleep apnea...
December 20, 2016: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28141665/association-of-sleep-disturbance-and-sexual-function-in-postmenopausal-women
#18
Juliana M Kling, JoAnn E Manson, Michelle J Naughton, M'hamed Temkit, Shannon D Sullivan, Emily W Gower, Lauren Hale, Julie C Weitlauf, Sara Nowakowski, Carolyn J Crandall
OBJECTIVE: Sleep disturbance and sexual dysfunction are common in menopause; however, the nature of their association is unclear. The present study aimed to determine whether sleep characteristics were associated with sexual activity and sexual satisfaction. METHODS: Sexual function in the last year and sleep characteristics (past 4 wk) were assessed by self-report at baseline for 93,668 women age 50 to 79 years enrolled in the Women's Health Initiative (WHI) Observational Study (OS)...
January 30, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28130217/longitudinal-evaluation-of-sleep-disordered-breathing-in-infants-with-prader-willi-syndrome
#19
Abdullah Khayat, Indra Narang, Saadoun Bin-Hasan, Reshma Amin, Suhail Al-Saleh
OBJECTIVE: To evaluate the course of sleep disordered breathing (SDB) in infants with Prader-Willi syndrome (PWS). DESIGN: Retrospective longitudinal observational study. SETTING: Sleep laboratory at The Hospital for Sick Children, Toronto, Canada. PATIENTS: Infants with PWS. MAIN OUTCOME MEASURES: The natural history of SDB in infants with PWS within 2 years from baseline assessment. RESULTS: We identified 28 (12 male) infants with PWS who had a baseline polysomnography (PSG) at a median age (interquartile (IQR)) of 0...
January 27, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28126479/positive-airway-pressure-therapy-in-heart-failure-patients-long-term-effects-on-lung-function
#20
Henrik Fox, Susanne Witzel, Thomas Bitter, Dieter Horstkotte, Olaf Oldenburg
PURPOSE: The prevalence of sleep-disordered breathing (SDB) in patients with heart failure (HF) is high. Positive airway pressure (PAP) is first-choice therapy, but recent data indicates that PAP therapy may increase mortality in HF patients with reduced ejection fraction (HF-REF) and predominant central sleep apnea (CSA). This study investigated long-term effects of PAP therapy on pulmonary function, including respiratory muscle strength. All patients underwent multichannel cardiorespiratory polysomnography (PSG) and comprehensive lung function testing at baseline and follow-up (mean 588±43days)...
January 23, 2017: Respiratory Physiology & Neurobiology
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