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https://www.readbyqxmd.com/read/28340449/right-hemisphere-pitch-mismatch-negativity-reduction-in-patients-with-major-depression-an-meg-study
#1
Noriaki Hirakawa, Yoji Hirano, Itta Nakamura, Shogo Hirano, Jinya Sato, Naoya Oribe, Takefumi Ueno, Shigenobu Kanba, Toshiaki Onitsuka
BACKGROUND: The mismatch negativity (MMN) component of the event-related potential and its magnetic counterpart, the MMNm, are generated by a mismatch between the physical features of a deviant stimulus and a neuronal sensory-memory trace produced by repetitive standard stimuli. Deficits in the MMN/MMNm have been reported in patients with major depression; however, the results are inconsistent. The present study investigated the pitch-MMNm in patients with major depression using whole-head 306-channel magnetoencephalography (MEG)...
March 19, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28330464/spectral-temporal-eeg-dynamics-of-speech-discrimination-processing-in-infants-during-sleep
#2
Phillip M Gilley, Kristin Uhler, Kaylee Watson, Christine Yoshinaga-Itano
BACKGROUND: Oddball paradigms are frequently used to study auditory discrimination by comparing event-related potential (ERP) responses from a standard, high probability sound and to a deviant, low probability sound. Previous research has established that such paradigms, such as the mismatch response or mismatch negativity, are useful for examining auditory processes in young children and infants across various sleep and attention states. The extent to which oddball ERP responses may reflect subtle discrimination effects, such as speech discrimination, is largely unknown, especially in infants that have not yet acquired speech and language...
March 22, 2017: BMC Neuroscience
https://www.readbyqxmd.com/read/28325448/diagnosis-of-autism-through-eeg-processed-by-advanced-computational-algorithms-a-pilot-study
#3
Enzo Grossi, Chiara Olivieri, Massimo Buscema
BACKGROUND: Multi-Scale Ranked Organizing Map coupled with Implicit Function as Squashing Time algorithm(MS-ROM/I-FAST) is a new, complex system based on Artificial Neural networks (ANNs) able to extract features of interest in computerized EEG through the analysis of few minutes of their EEG without any preliminary pre-processing. A proof of concept study previously published showed accuracy values ranging from 94%-98% in discerning subjects with Mild Cognitive Impairment and/or Alzheimer's Disease from healthy elderly people...
April 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28325146/hypersexuality-as-a-neuropsychiatric-disorder-the-neurobiology-and-treatment-options
#4
Hatta Sidi, Muna Asiff, Jaya Kumar, Srijit Das, Nurul Hazwani Hatta, Cesar Alfonso
Hypersexuality refers to abnormally increased or extreme involvement in any sexual activity. It is clinically challenging, presents trans-diagnostically and there is extensive medical literature addressing nosology, pathogenesis and neuropsychiatric aspects. Classification includes deviant behaviours, diagnosable entities related to impulsivity, and obsessional phenomena. Some clinicians view an increase in sexual desire as 'normal' while psychodynamic theorists consider it ego-defensive at times alleviating unconscious anxiety rooted in intrapsychic conflicts...
March 21, 2017: Current Drug Targets
https://www.readbyqxmd.com/read/28325066/comprehensive-analysis-to-explain-reduced-or-increased-sod1-enzymatic-activity-in-als-patients-and-their-relatives
#5
Isil Keskin, Anna Birve, Mariusz Berdynski, Karin Hjertkvist, Reza Rofougaran, Torbjörn K Nilsson, Jonathan D Glass, Stefan L Marklund, Peter M Andersen
OBJECTIVE: To characterise stabilities in erythrocytes of mutant SOD1 proteins, compare SOD1 enzymatic activities between patients with different genetic causes of ALS and search for underlying causes of deviant SOD1 activities in individuals lacking SOD1 mutations. METHODS: Blood samples from 4072 individuals, ALS patients with or without a SOD1 mutation, family members and controls were studied. Erythrocyte SOD1 enzymatic activities normalised to haemoglobin content were determined, and effects of haemoglobin disorders on dismutation assessed...
March 21, 2017: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
https://www.readbyqxmd.com/read/28324698/eye-stabilization-reflexes-in-traumatic-and-non-traumatic-chronic-neck-pain-patients
#6
Britta K Ischebeck, Jurryt de Vries, Malou Janssen, Jan Paul van Wingerden, Gert-Jan Kleinrensink, Jos N van der Geest, Maarten A Frens
BACKGROUND: Many chronic neck pain patients experience problems with vision. These problems are possibly induced by deviations of the eye stabilization reflexes. It is not known whether these eye reflex alterations occur both in traumatic and non-traumatic neck pain patients. OBJECTIVE: To investigate if the cervico-ocular reflex (COR) and the vestibulo-ocular reflex (VOR) are changed in tertiary care patients with prolonged, chronic neck pain with various origin of complaints...
March 16, 2017: Musculoskelet Sci Pract
https://www.readbyqxmd.com/read/28320627/maximal-ambient-noise-levels-and-type-of-voice-material-required-for-valid-use-of-smartphones-in-clinical-voice-research
#7
Jean Lebacq, Jean Schoentgen, Giovanna Cantarella, Franz Thomas Bruss, Claudia Manfredi, Philippe DeJonckere
PURPOSE: Smartphone technology provides new opportunities for recording standardized voice samples of patients and transmitting the audio files to the voice laboratory. This drastically improves the achievement of baseline designs, used in research on efficiency of voice treatments. However, the basic requirement is the suitability of smartphones for recording and digitizing pathologic voices (mainly characterized by period perturbations and noise) without significant distortion. In a previous article, this was tested using realistic synthesized deviant voice samples (/a:/) with three precisely known levels of jitter and of noise in all combinations...
March 17, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28314681/duration-and-frequency-mismatch-negativity-shows-no-progressive-reduction-in-early-stages-of-psychosis
#8
Daisuke Koshiyama, Kenji Kirihara, Mariko Tada, Tatsuya Nagai, Shinsuke Koike, Motomu Suga, Tsuyoshi Araki, Kiyoto Kasai
The auditory mismatch negativity (MMN) is a component of event-related potentials, which is being increasingly recognized as a candidate biomarker for early stages of psychosis. Although previous cross-sectional studies have demonstrated small MMN amplitude in early stages of psychosis, it remains unknown whether small MMN amplitude is due to progressive reduction during the early course. In this study, we investigated longitudinal changes of MMN in early stages of psychosis. Participant included 14 patients with first-episode psychosis (FEP), 16 individuals with ultra-high risk (UHR), and 16 healthy control subjects (HC)...
March 14, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28314229/how-did-the-good-school-toolkit-reduce-the-risk-of-past-week-physical-violence-from-teachers-to-students-qualitative-findings-on-pathways-of-change-in-schools-in-luwero-uganda
#9
N Kyegombe, S Namakula, J Mulindwa, J Lwanyaaga, D Naker, S Namy, J Nakuti, J Parkes, L Knight, E Walakira, K M Devries
Violence against children is a serious violation of children's rights with significant impacts on current and future health and well-being. The Good School Toolkit (GST) is designed to prevent violence against children in primary schools through changing schools' operational cultures. Conducted in the Luwero District in Uganda between 2012 and 2014, findings from previous research indicate that the Toolkit reduced the odds of past week physical violence from school staff (OR = 0.40, 95%CI 0.26-0.64, p < 0...
March 7, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28303421/oxytocin-receptor-gene-variant-interacts-with-intervention-delivery-format-in-predicting-intervention-outcomes-for-youth-with-conduct-problems
#10
Andrea L Glenn, John E Lochman, Thomas Dishion, Nicole P Powell, Caroline Boxmeyer, Lixin Qu
Coping Power is an evidence-based preventive intervention program for youth with aggressive behavior problems that has traditionally been delivered in small group formats. Because of concerns about iatrogenic effects secondary to aggregation of high risk youth, the current study examined whether genetic risk may moderate intervention outcome when youth were randomly assigned to group versus individual formats of an intervention. The oxytocin receptor gene (OXTR) has been associated with social behavior and may influence susceptibility to social reinforcement in general and deviant peer influence in particular...
March 16, 2017: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/28301962/overcoming-obesity
#11
Elaine Seaton Banerjee, Sharon J Herring, Katelyn E Hurley, Katherine Puskarz, Kyle Yebernetsky, Marianna LaNoue
PURPOSE: Low-income, African American women are disproportionately impacted by obesity. Little is known about the interactions between low-income, African American women who successfully lost weight and their primary care physicians (PCPs). DESIGN: Mixed methods, positive deviance study. SETTING: Urban university-based family medicine practice. PARTICIPANTS: The positive deviance group comprised low-income, African American women who were obese, lost 10% body weight, and maintained this loss for 6 months...
January 1, 2017: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/28300957/dosage-dependent-effect-of-high-resistance-straw-exercise-in-dysphonic-and-non-dysphonic-women
#12
Sabrina Mazzer Paes, Mara Behlau
Purpose: to study the dosage dependent effect of high-resistance straw exercise in women with behavioral dysphonia and in vocally healthy women. Methods: 25 dysphonic women (DG), with average age of 35 years (SD = 10.5) and 30 vocally healthy women (VHG), with average age of 31.6 years (SD = 10.3). The participants produced a continuous sound into a thin high-resistance straw for seven minutes, being interrupted after the first, third, fifth and seventh minute. At each interval, speech samples were recorded (sustained vowel and counting up to 20) and subsequently acoustically analyzed...
March 9, 2017: CoDAS
https://www.readbyqxmd.com/read/28292430/dangerous-liaisons-deviant-endothelium-notches-toward-tumor-metastasis
#13
Peipei Guo, Shahin Rafii
In this issue of Cancer Cell, Wieland et al. uncover a feedback loop in which tumor cells, by augmenting Notch signaling, provoke a senescent and pro-inflammatory state in endothelial cells, promoting neutrophil infiltration, tumor cell adhesion, and metastasis. Interfering with this Notch-dependent crosstalk may be a therapeutic approach to block metastasis.
March 13, 2017: Cancer Cell
https://www.readbyqxmd.com/read/28288908/human-centromedian-parafascicular-complex-signals-sensory-cues-for-goal-oriented-behavior-selection
#14
Inga M Schepers, Anne-Kathrin Beck, Susann Bräuer, Kerstin Schwabe, Mahmoud Abdallat, Pascale Sandmann, Reinhard Dengler, Jochem W Rieger, Joachim K Krauss
Experimental research has shown that the centromedian-parafascicular complex (CM-Pf) of the intralaminar thalamus is activated in attentional orienting and processing of behaviorally relevant stimuli. These observations resulted in the hypothesis that the CM-Pf plays a pivotal role in goal-oriented behavior selection. We here set out to test this hypothesis with electrophysiological recordings from patients with electrodes implanted in CM-Pf for deep brain stimulation (DBS) treatment of chronic neuropathic pain...
March 10, 2017: NeuroImage
https://www.readbyqxmd.com/read/28288554/the-associations-between-substance-use-sexual-behaviors-bullying-deviant-behaviors-health-and-cyber-dating-abuse-perpetration
#15
Joris Van Ouytsel, Elizabeth Torres, Hye Jeong Choi, Koen Ponnet, Michel Walrave, Jeff R Temple
Dating violence is an important public health concern and is considered to be a form of school violence. While digital technologies have enabled perpetrators of dating violence to target their victims online (cyber dating abuse), little is known about how this form of perpetration relates to specific adolescent risk behaviors. This brief research report focuses on the associations between substance use, sexual behaviors, deviant behaviors, self-reported health, and cyber dating abuse perpetration. Participants included 705 ethnically diverse adolescents ( n = 408; 57...
April 2017: Journal of School Nursing: the Official Publication of the National Association of School Nurses
https://www.readbyqxmd.com/read/28288158/stimulus-specific-adaptation-in-a-recurrent-network-model-of-primary-auditory-cortex
#16
Tohar S Yarden, Israel Nelken
Stimulus-specific adaptation (SSA) occurs when neurons decrease their responses to frequently-presented (standard) stimuli but not, or not as much, to other, rare (deviant) stimuli. SSA is present in all mammalian species in which it has been tested as well as in birds. SSA confers short-term memory to neuronal responses, and may lie upstream of the generation of mismatch negativity (MMN), an important human event-related potential. Previously published models of SSA mostly rely on synaptic depression of the feedforward, thalamocortical input...
March 13, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28287844/intersectional-epistemologies-of-ignorance-how-behavioral-and-social-science-research-shapes-what-we-know-think-we-know-and-don-t-know-about-u-s-black-men-s-sexualities
#17
Lisa Bowleg, Ana María Del Río-González, Sidney L Holt, Carolin Pérez, Jenné S Massie, Jessica E Mandell, Cheriko A Boone
Epistemologies of ignorance describe how ignorance influences the production of knowledge. Advancing an intersectional epistemologies of ignorance approach that examines how conscious (or unconscious) ignorance about racism, heterosexism, and classism shapes empirical knowledge about Black men's sexualities, we conducted a critical review of the behavioral and social science research on U.S. Black men, ages 18 and older, for two time frames: pre-1981 and the most recent decade, 2006-2016. Our search yielded 668 articles, which we classified into five categories: sexual violence, sexual experiences and expressions, sexual identities, cultural and social-structural influences, and sexual health and sexual risk...
March 13, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/28283834/risk-factors-for-comorbid-oppositional-defiant-disorder-in-attention-deficit-hyperactivity-disorder
#18
Siri D S Noordermeer, Marjolein Luman, Wouter D Weeda, Jan K Buitelaar, Jennifer S Richards, Catharina A Hartman, Pieter J Hoekstra, Barbara Franke, Dirk J Heslenfeld, Jaap Oosterlaan
Oppositional defiant disorder (ODD) is highly prevalent in attention-deficit/hyperactivity disorder (ADHD). Individuals with both ADHD and ODD (ADHD + ODD) show a considerably worse prognosis compared with individuals with either ADHD or ODD. Therefore, identification of risk factors for ADHD + ODD is essential and may contribute to the development of (early) preventive interventions. Participants were matched for age, gender, and ADHD-subtype (diagnostic groups), and did not differ in IQ. Predictors included pre- and perinatal risk factors (pregnancy duration, birth weight, maternal smoking during pregnancy), transgenerational factors (parental ADHD; parental warmth and criticism in diagnostic groups), and postnatal risk factors (parental socioeconomic status [SES], adverse life events, deviant peer affiliation)...
March 10, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28278058/the-queerness-of-the-drive
#19
Teresa de Lauretis
The view of sexuality Freud first proposed in the Three Essays on the Theory of Sexuality contains a discrepancy between the sexuality perverse and polymorphous described in the first two essays and the biologically directed, reproductive sexuality of the third essay. According to Jean Laplanche, the theorist of psychoanalysis who is Freud's closest reader and translator, the discrepancy is due to two contradictory opinions Freud apparently held at different moments of his writing: one, that sexuality is exogenous, an effect of seduction by adults; two, that sexuality is endogenous, innate in the human biological organism...
February 16, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/28263878/valence-and-arousal-of-emotional-stimuli-impact-cognitive-motor-performance-in-an-oddball-task
#20
Yingzhi Lu, Kyle J Jaquess, Bradley D Hatfield, Chenglin Zhou, Hong Li
It is widely recognized that emotions impact an individual's ability to perform in a given task. However, little is known about how emotion impacts the various aspects of cognitive -motor performance. We recorded event-related potentials (ERPs) and chronometric responses from twenty-six participants while they performed a cognitive-motor oddball task in regard to four categories of emotional stimuli (high-arousing positive-valence, low-arousing positive-valence, high-arousing negative-valence, and low-arousing negative-valence) as "deviant" stimuli...
March 2, 2017: Biological Psychology
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