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https://www.readbyqxmd.com/read/28441882/work-right-to-right-work-an-automythology-of-chronic-illness-and-work
#1
Lavanya Vijayasingham
Objectives Chronic illness is known to disrupt and redirect the usual course of work trajectories. This article aims to portray the longitudinal course of negotiating work after multiple sclerosis. Methods Using therapy and personal journals to reconstruct memories and experience, an autoethnography is produced and narrated within Campbell's "Hero's Journey" automythology framework. Results The narrative highlights the intrasubjectivity of illness meaning-the changing internal meaning-making and external behavior and decision-making dynamics...
January 1, 2017: Chronic Illness
https://www.readbyqxmd.com/read/28436834/active-auditory-experience-in-infancy-promotes-brain-plasticity-in-theta-and-gamma-oscillations
#2
Gabriella Musacchia, Silvia Ortiz-Mantilla, Naseem Choudhury, Teresa Realpe-Bonilla, Cynthia Roesler, April A Benasich
Language acquisition in infants is driven by on-going neural plasticity that is acutely sensitive to environmental acoustic cues. Recent studies showed that attention-based experience with non-linguistic, temporally-modulated auditory stimuli sharpens cortical responses. A previous ERP study from this laboratory showed that interactive auditory experience via behavior-based feedback (AEx), over a 6-week period from 4- to 7-months-of-age, confers a processing advantage, compared to passive auditory exposure (PEx) or maturation alone (Naïve Control, NC)...
April 15, 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/28435465/hypertension-cerebrovascular-impairment-and-cognitive-decline-in-aged-a%C3%AE-pp-ps1-mice
#3
Maximilian Wiesmann, Valerio Zerbi, Diane Jansen, Dieter Lütjohann, Andor Veltien, Arend Heerschap, Amanda J Kiliaan
Cardiovascular risk factors, especially hypertension, are also major risk factors for Alzheimer's disease (AD). To elucidate the underlying vascular origin of neurodegenerative processes in AD, we investigated the relation between systolic blood pressure (SBP) cerebral blood flow (CBF) and vasoreactivity with brain structure and function in a 16-18 months old double transgenic AβPPswe/PS1dE9 (AβPP/PS1) mouse model for AD. These aging AβPP/PS1 mice showed an increased SBP linked to a declined regional CBF...
2017: Theranostics
https://www.readbyqxmd.com/read/28430531/phonological-development-of-danish-speaking-children-a-normative-cross-sectional-study
#4
Marit Carolin Clausen, Annette Fox-Boyer
Detailed knowledge about speech development in children acquiring different languages provides important information from a clinical and a theoretical perspective: First, it provides a baseline for the evaluation of whether a child shows typical, delayed or deviant speech development. Further, differences in speech development across languages can help to understand how the phonological systems of ambient languages affects children's speech acquisition. To date, little is known about Danish. It was suggested, however, that the acquisition process might be slower for Danish-speaking children due to the "blurry" sound structure of Danish...
April 21, 2017: Clinical Linguistics & Phonetics
https://www.readbyqxmd.com/read/28427795/reappraisal-to-the-study-of-4e-bp1-as-an-mtor-substrate-a-normative-critique
#5
REVIEW
Asiya Batool, Sabreena Aashaq, Khurshid Iqbal Andrabi
mTOR-4E-BP1 axis is regarded as the best oncogenic circuitry impinging on translational control whereby mTORC1 dictates post-translational regulation of 4E-BP1. This review provides new insights into the molecular network of signalling pathways highlighting the recent explosion of studies in respect to the deviant behaviour of 4E-BP1 towards mTORC1. Despite the striking conservation of mTOR nexus, the eccentric phosphorylation dynamics of 4E-BP1 negate the apparent linear architecture of mTORC1 attesting the importance of other kinases that may evoke cross-talks with the conventional frame, most of which are enlisted in the manuscript...
April 8, 2017: European Journal of Cell Biology
https://www.readbyqxmd.com/read/28423456/progesterone-resistance-in-endometriosis-origins-consequences-and-interventions
#6
Bansari G Patel, Martin Rudnicki, Jie Yu, Yimin Shu, Robert N Taylor
Endometriosis is a common cause of pelvic pain and affects up to 10% of women of reproductive age. Aberrant progesterone signaling in the endometrium plays a significant role in impaired decidualization and establishment of ectopic endometrial implants. Eutopic endometrial cells from women with endometriosis fail to downregulate genes needed for decidualization, such as those involved in cell cycle regulation, leading to unbridled proliferation. Several causes of progesterone resistance in the endometrium have been postulated, including congenital "preconditioning", whereby the in utero environment renders infants susceptible to neonatal uterine bleeding and endometriosis...
April 19, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28422296/keeping-out-and-getting-in-reframing-emergency-department-gatekeeping-as-structural-competence
#7
Mara Buchbinder
Sociologists have tended to frame medical gatekeeping as an exclusionary social practice, delineating how practitioners and clerical staff police the moral boundaries of medicine by keeping out patients who are categorised as 'bad', 'deviant', or otherwise problematic. Yet medical gatekeeping, understood more broadly, can include not only keeping patients out of particular clinical settings, but also redirecting them to alternative sources of care. In this article, I draw on qualitative analysis of audio-recorded patient-provider interactions in a United States emergency department (ED) to illustrate medical gatekeeping as a two-step process of, first, categorising certain patient complaints as unsuitable for treatment within a particular setting, and second, diverting patients to alternative sites for care...
April 19, 2017: Sociology of Health & Illness
https://www.readbyqxmd.com/read/28421018/the-emergence-of-explicit-knowledge-in-a-serial-reaction-time-task-the-role-of-experienced-fluency-and-strength-of-representation
#8
Sarah Esser, Hilde Haider
The Serial Reaction Time Task (SRTT) is an important paradigm to study the properties of unconscious learning processes. One specifically interesting and still controversially discussed topic are the conditions under which unconsciously acquired knowledge becomes conscious knowledge. The different assumptions about the underlying mechanisms can contrastively be separated into two accounts: single system views in which the strengthening of associative weights throughout training gradually turns implicit knowledge into explicit knowledge, and dual system views in which implicit knowledge itself does not become conscious...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28402177/intersectional-harassment-and-deviant-embodiment-among-autistic-adults-dis-ability-gender-and-sexuality
#9
Jessica Penwell Barnett
Harassment scholarship increasingly attends to the intersectional nature of harassment and its function within systems of domination. However, little of this work includes disability. In-depth interviews with 24 adults on the autism spectrum in the USA demonstrate the intersections of gender, sexuality and (dis)ability in the construction of deviant embodiments as targets for harassment. These intersections also shape how participants made sense of these experiences of violence. Participants' disability characteristics were often read as gender or sexual variance, with harassers relying on sexist and heterosexist constructs to frighten, demean or humiliate them for disability characteristics...
April 12, 2017: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/28395037/moral-panic-and-social-justice-a-guide-for-analyzing-social-problems
#10
Michael H Eversman, Jason D P Bird
Professional social work has long been concerned with social justice, social policy, and the relationship between social treatment and social control. However, at times, potential threats to social cohesion become exaggerated in the service of supporting suppressive policies. British sociologist Stanley Cohen referred to such periods as moral panics, which assign unwarranted blame and stigma to sociopolitically weaker, unpopular groups. By constructing those associated with a given social problem as deviant and downplaying underlying structural causes, moral panics foster the enactment of social policies that entrench social disparity and injustice...
January 1, 2017: Social Work
https://www.readbyqxmd.com/read/28394728/destroying-false-images-of-god-the-experiences-of-lgbt-catholics
#11
Angele Deguara
This paper is about how lesbian, gay, bisexual and trans (LGBT) Catholics imagine God1(1) and how images of God change in parallel with their self-image. The study is based on qualitative research with LGBT Catholics most of whom are members of Drachma LGBTI in Malta or Ali d'Aquila in Palermo, Sicily. LGBT Catholics' image of God changes as they struggle to reconcile their religious and sexual identities, as they go through a process of "conversion" from deviants and sinners to loved children of God. One study participant compares his faith in God to peeling an onion: "With every layer one peels off, one destroys false images of God...
April 10, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/28389236/visual-stimuli-approaching-toward-the-body-influence-temporal-expectations-about-subsequent-somatosensory-stimuli
#12
Tsukasa Kimura, Jun'ichi Katayama
The present study investigated whether visual stimuli approaching the body influence temporal expectations about subsequent somatosensory stimuli. To examine this question, we recorded event-related brain potentials (ERPs) during a simple reaction time task using somatosensory stimuli. Fourteen participants were asked to place their arms on a desk, and three light-emitting diodes (LEDs) were placed at equal distances between their arms. Each trial was composed of three visual stimuli (i.e., LEDs), and one subsequent electrical stimulus (i...
April 4, 2017: Brain Research
https://www.readbyqxmd.com/read/28385587/late-deviance-detection-in-rats-is-reduced-while-early-deviance-detection-is-augmented-by-the-nmda-receptor-antagonist-mk-801
#13
L Harms, W R Fulham, J Todd, C Meehan, U Schall, D M Hodgson, P T Michie
One of the most robust electrophysiological features of schizophrenia is reduced mismatch negativity, a component of the event related potential (ERP) induced by rare and unexpected stimuli in an otherwise regular pattern. Emerging evidence suggests that mismatch negativity (MMN) is not the only ERP index of deviance detection in the mammalian brain and that sensitivity to deviant sounds in a regular background can be observed at earlier latencies in both the human and rodent brain. Pharmacological studies in humans and rodents have previously found that MMN reductions similar to those seen in schizophrenia can be elicited by N-methyl-d-aspartate (NMDA) receptor antagonism, an observation in agreement with the hypothesised role of NMDA receptor hypofunction in schizophrenia pathogenesis...
April 3, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28384522/poor-nutrition-and-bullying-behaviors-a-comparison-of-deviant-and-non-deviant-youth
#14
Dylan B Jackson, Michael G Vaughn, Christopher P Salas-Wright
Research on the topic of bullying has revealed that a substantial number of youth are bullied each year. Even so, a complete understanding of the origins of bullying behaviors remains elusive. In the current study, we propose that poor nutrition may constitute an important modifiable risk factor for bullying behaviors during adolescence, and that behavioral sensitivity to nutrition may vary across deviant and non-deviant youth. We employ data from the US sample of youth (52% male) ages 10-17 from the 2009-2010 Health Behaviour in School-Aged Children (HBSC) study to examine our hypothesis (N = 8753)...
April 3, 2017: Journal of Adolescence
https://www.readbyqxmd.com/read/28384376/a-two-step-method-to-identify-positive-deviant-physician-organizations-of-accountable-care-organizations-with-robust-performance-management-systems
#15
Alexander F Pimperl, Hector P Rodriguez, Julie A Schmittdiel, Stephen M Shortell
OBJECTIVE: To identify positive deviant (PD) physician organizations of Accountable Care Organizations (ACOs) with robust performance management systems (PMSYS). DATA SOURCE: Third National Survey of Physician Organizations (NSPO3, n = 1,398). STUDY DESIGN: Organizational and external factors from NSPO3 were analyzed. DATA COLLECTION/EXTRACTION METHODS: Linear regression estimated the association of internal and contextual factors on PMSYS...
April 6, 2017: Health Services Research
https://www.readbyqxmd.com/read/28383975/to-the-fringe-and-back-violent-extremism-and-the-psychology-of-deviance
#16
Arie W Kruglanski, Katarzyna Jasko, Marina Chernikova, Michelle Dugas, David Webber
We outline a general psychological theory of extremism and apply it to the special case of violent extremism (VE). Extremism is defined as motivated deviance from general behavioral norms and is assumed to stem from a shift from a balanced satisfaction of basic human needs afforded by moderation to a motivational imbalance wherein a given need dominates the others. Because motivational imbalance is difficult to sustain, only few individuals do, rendering extreme behavior relatively rare, hence deviant. Thus, individual dynamics translate into social patterns wherein majorities of individuals practice moderation, whereas extremism is the province of the few...
April 2017: American Psychologist
https://www.readbyqxmd.com/read/28377265/lexical-influence-on-stress-processing-in-a-fixed-stress-language
#17
Linda Garami, Anett Ragó, Ferenc Honbolygó, Valéria Csépe
In the present study, we investigate how lexicality affects the processing of suprasegmental features at the word level. In contrast to earlier studies which analyzed the role of either segmental or suprasegmental feature in language processing our aim was to investigate the effect of the lexical status on the processing of violated stress pattern defined by linguistic rules. We have conducted a passive oddball ERP experiment, presenting a frequent CVCV word with legal (familiar) and illegal (unfamiliar) stress patterns...
April 2, 2017: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/28368147/the-three-second-subjective-present-a-critical-review-and-a-new-proposal
#18
Peter A White
It has been argued that there is a "subjective present" or "experienced moment" of about 3 seconds in duration, involving automatic binding of events into perceptual units on that time scale. Research on topics that have been taken as relevant to this proposal is reviewed. The topics include accuracy in reproduction of stimulus durations, synchronization of behavior with a regular beat, mental rhythmization of a regular beat, time units in behavior, segmentation of observed behavior into meaningful units, time scale of reversals of perception with bistable ambiguous figures, time scale of inhibition of return in visual search, and EEG responses to deviant stimuli in series of repeating stimuli...
April 3, 2017: Psychological Bulletin
https://www.readbyqxmd.com/read/28367763/externalizing-and-internalizing-pathways-to-mexican-american-adolescents-risk-taking
#19
Nancy A Gonzales, Yu Liu, Michaeline Jensen, Jenn Yun Tein, Rebecca M B White, Julianna Deardorff
This study used four waves of data from a longitudinal study of 749 Mexican origin youths to test a developmental cascades model linking contextual adversity in the family and peer domains in late childhood to a sequence of unfolding processes hypothesized to predict problem substance use and risky sexual activity (greater number of sex partners) in late adolescence. Externalizing and internalizing problems were tested as divergent pathways, with youth-reported and mother-reported symptoms examined in separate models...
April 3, 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28366617/acute-dosing-of-vortioxetine-strengthens-event-related-brain-activity-associated-with-engagement-of-attention-and-cognitive-functioning-in-rats
#20
Bettina Laursen, Cecilie H Bundgaard, Carina Graversen, Morten Grupe, Connie Sanchez, Steven C Leiser, Helge B D Sorensen, Asbjørn M Drewes, Jesper F Bastlund
Studies of the antidepressant vortioxetine have demonstrated beneficial effects on cognitive dysfunction associated with depression. To elucidate how vortioxetine modulates neuronal activity during cognitive processing we investigated the effects of vortioxetine (3 and 10 mg/kg) in rats performing an auditory oddball (deviant target) task. We investigated neuronal activity in target vs non-target tone responses in vehicle-treated animals using electroencephalographic (EEG) recordings. Furthermore, we characterized task performance and EEG changes in target tone responses of vortioxetine vs controls...
March 30, 2017: Brain Research
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