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https://www.readbyqxmd.com/read/29320864/diagnostic-performance-of-static-single-scan-stress-perfusion-cardiac-computed-tomography-in-detecting-hemodynamically-significant-coronary-artery-stenosis-a-comparison-with-combined-invasive-coronary-angiography-and-cardiovascular-magnetic-resonance-myocardial
#1
Inyoung Song, Jeong Geun Yi, Jeong Hee Park, Mi Young Kim, Je Kyoun Shin, Sung Min Ko
Background Non-invasive anatomical and physiological evaluations of coronary artery disease (CAD) may be obtained with static single-scan stress perfusion cardiac computed tomography (SSPCT). Purpose To determine the diagnostic performance of static SSPCT for identifying hemodynamically significant CAD. Material and Methods This prospective study included 29 patients with suspected or known CAD who underwent static SSPCT, cardiovascular magnetic resonance myocardial perfusion imaging (CMR-MPI), and invasive coronary angiography (ICA)...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29319132/evaluation-of-changes-in-perfusion-defect-and-left-ventricular-systolic-function-using-tc-99m-tetrofosmin-single-photon-emission-computed-tomography-over-3-month-period-in-patients-of-acute-myocardial-infarction-undergoing-primary-angioplasty
#2
Anil Kumar Avs, P G Kumar, Ajay Swami, Yiteedra Dinker
BACKGROUND: After a primary transluminal coronary angioplasty (PTCA) following AMI (acute myocardial infarction), the perfusion defect and LV (left ventricular) function recover/change over a period of time. The analysis immediately after the procedure may not be true depiction of the exact success of the procedure. There is varying and scanty information available on the natural course of changes in these parameters after a successful PTCA. We hypothesized that majority of change occurs at 3-4 month period...
January 10, 2018: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/29318380/dissipation-kinetics-and-risk-assessment-of-chlorfenapyr-on-tomato-and-cabbage
#3
Sandip Patra, Pritam Ganguly, Suhrid Ranjan Barik, Arunava Samanta
A field experiment was conducted over two seasons to evaluate the dissipation kinetics and assess the risks of chlorfenapyr in tomato and cabbage following foliar application of chlorfenapyr 10% SC at 100 and 200 g a.i. ha-1. Samples of tomato, cabbage, and soil were analyzed and quantified by gas chromatography-electron capture detector (GC-ECD). The limit of detection (LOD) and limit of quantification (LOQ) of chlorfenapyr were found to be 0.01 and 0.03 mg kg-1, respectively, in tomato, cabbage, and soil...
January 9, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29315405/hipmcl-a-high-performance-parallel-implementation-of-the-markov-clustering-algorithm-for-large-scale-networks
#4
Ariful Azad, Georgios A Pavlopoulos, Christos A Ouzounis, Nikos C Kyrpides, Aydin Buluç
Biological networks capture structural or functional properties of relevant entities such as molecules, proteins or genes. Characteristic examples are gene expression networks or protein-protein interaction networks, which hold information about functional affinities or structural similarities. Such networks have been expanding in size due to increasing scale and abundance of biological data. While various clustering algorithms have been proposed to find highly connected regions, Markov Clustering (MCL) has been one of the most successful approaches to cluster sequence similarity or expression networks...
January 5, 2018: Nucleic Acids Research
https://www.readbyqxmd.com/read/29315366/long-term-prognostic-value-of-single-photon-emission-computed-tomography-myocardial-perfusion-imaging-after-primary-pci-for-stemi
#5
Jeff M Smit, Maaike P Hermans, Aukelien C Dimitriu-Leen, Alexander R van Rosendael, Petra Dibbets-Schneider, Lioe-Fee de Geus-Oei, Bart J Mertens, Martin J Schalij, Jeroen J Bax, Arthur J Scholte
Aims: The aim of this study was to determine the long-term prognostic value of infarct size and myocardial ischaemia on single-photon emission computed tomography myocardial perfusion imaging (SPECT MPI) after primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI). Methods and results: In total, 1092 STEMI patients who underwent primary PCI and SPECT MPI within 1-6 months were included (median follow-up time of 6...
January 5, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29311035/the-reality-of-disability-multidimensional-poverty-of-people-with-disabled-and-their-families-in-latin-america
#6
Mónica Pinilla-Roncancio
BACKGROUND: Disability and poverty are interconnected and although this relationship has been recognised, there is a lack of empirical evidence to support any possible causal relationship in this topic, particularly in the context of Latin America (LA). HYPOTHESIS: This study tests the hypothesis "Disability increases the risk of multidimensional poverty of people living with disabilities and their families". METHODS: Using national census data from Brazil, Chile, Colombia, Costa Rica and Mexico, the Global Multidimensional Poverty Index (Global MPI) was calculated with the aim of measuring and comparing the levels of multidimensional poverty of people living in households with and without disabled members in the five countries...
December 30, 2017: Disability and Health Journal
https://www.readbyqxmd.com/read/29301486/comprehensive-geriatric-assessment-in-patients-undergoing-transcatheter-aortic-valve-implantation-results-from-the-cga-tavi-multicentre-registry
#7
Andrea Ungar, Giulio Mannarino, Nathalie van der Velde, Jan Baan, Marie-Pierre Thibodeau, Jean-Bernard Masson, Gennaro Santoro, Martijn van Mourik, Sofie Jansen, Cornelia Deutsch, Peter Bramlage, Jana Kurucova, Martin Thoenes, Stefania Maggi, Andreas W Schoenenberger
BACKGROUND: In older patients with aortic stenosis (AS) undergoing TAVI, the potential role of prior CGA is not well established. To explore the value of comprehensive geriatric assessment (CGA) for predicting mortality and/or hospitalisation within the first 3 months after transcatheter aortic valve implantation (TAVI). METHODS: An international, multi-centre, prospective registry (CGA-TAVI) was established to gather data on CGA results and medium-term outcomes in geriatric patients undergoing TAVI...
January 4, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29301441/use-of-the-fetal-myocardial-performance-index-in-monochorionic-diamniotic-twin-pregnancy-a-prospective-cohort-and-nested-case-control-study
#8
Amanda Henry, Saranya Gopikrishna, Aditi Mahajan, Jennifer Alphonse, Neama Meriki, Alec W Welsh
AIMS: Assess clinical utility of the fetal Myocardial Performance Index (MPI) in evaluation and management of monochorionic, diamniotic twin (MCDA) pregnancies. METHODS: Prospective cohort of a) initially uncomplicated MCDA b) Complicated MCDA, including twin-twin transfusion syndrome (TTTS), selective intrauterine growth restriction (sIUGR), and liquor and/or growth discordance (L/GD) not meeting TTTS or sIUGR criteria. TTTS and sIUGR were case-control matched...
January 4, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29300729/novel-magnetic-multicore-nanoparticles-designed-for-mpi-and-other-biomedical-applications-from-synthesis-to-first-in-vivo-studies
#9
Harald Kratz, Matthias Taupitz, Angela Ariza de Schellenberger, Olaf Kosch, Dietmar Eberbeck, Susanne Wagner, Lutz Trahms, Bernd Hamm, Jörg Schnorr
Synthesis of novel magnetic multicore particles (MCP) in the nano range, involves alkaline precipitation of iron(II) chloride in the presence of atmospheric oxygen. This step yields green rust, which is oxidized to obtain magnetic nanoparticles, which probably consist of a magnetite/maghemite mixed-phase. Final growth and annealing at 90°C in the presence of a large excess of carboxymethyl dextran gives MCP very promising magnetic properties for magnetic particle imaging (MPI), an emerging medical imaging modality, and magnetic resonance imaging (MRI)...
2018: PloS One
https://www.readbyqxmd.com/read/29297287/scaling-bioinformatics-applications-on-hpc
#10
Mike Mikailov, Fu-Jyh Luo, Stuart Barkley, Lohit Valleru, Stephen Whitney, Zhichao Liu, Shraddha Thakkar, Weida Tong, Nicholas Petrick
BACKGROUND: Recent breakthroughs in molecular biology and next generation sequencing technologies have led to the expenential growh of the sequence databases. Researchrs use BLAST for processing these sequences. However traditional software parallelization techniques (threads, message passing interface) applied in newer versios of BLAST are not adequate for processing these sequences in timely manner. METHODS: A new method for array job parallelization has been developed which offers O(T) theoretical speed-up in comparison to multi-threading and MPI techniques...
December 28, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/29290377/reoperation-after-laparoscopic-colorectal-surgery-does-the-laparoscopic-approach-have-any-advantages
#11
Noelia Ibáñez, Jesús Abrisqueta, Juan Luján, Pedro Sánchez, María Teresa Soriano, Julio Arevalo-Pérez, Pascual Parrilla
INTRODUCTION: The laparoscopic approach in colorectal complications is controversial because of its difficulty. However, it has been proven that it can provide advantages over open surgery. The aim of this study is to compare laparoscopic approach in reoperations for complications after colorectal surgery with the open approach taking into account the severity of the patient prior to reoperation. METHODS: Patients who underwent laparoscopic colorectal surgery from January 2006 to December 2015 were retrospectively reviewed...
December 28, 2017: Cirugía Española
https://www.readbyqxmd.com/read/29282853/contrast-enhanced-ultrasound-using-bolus-injections-of-contrast-agent-for-assessment-of-postprandial-microvascular-blood-volume-in-human-skeletal-muscle
#12
Kenneth H Mertz, Jacob Bülow, Lars Holm
Methods capable of measuring blood flow in a tissue-specific manner are needed. The purpose of this study was to investigate whether contrast-enhanced ultrasound (CEUS) using bolus injections of SonoVue® is an useful method for assessing postprandial changes in microvascular perfusion in the vastus lateralis muscle. Ten healthy, young subjects were recruited for this study. Six subjects participated in washout and reproducibility protocols to assess washout time of SonoVue® and the reproducibility of the method when measuring microvascular blood volume (MBV)...
December 27, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/29278941/characteristics-of-lower-airway-inflammatory-changes-in-the-minimal-persistent-inflammation-of-allergic-rhinitis-in-mice
#13
Jie Xu, Li Gao, Hongbing Yao, Rong Zhang, Na Liu, Lijia Wang, Enmei Liu, Jihong Dai, Zhou Fu
OBJECTIVE: This study aims to establish an experimental mouse model of minimal persistent inflammation (MPI), observe the features of inflammation and hyper-responsiveness of the upper/lower airways, and explore the relationship between inflammation and hyper-responsiveness in the upper/lower airways. METHODS: Sixty-four female BALB/c mice were randomly divided into four groups: allergic rhinitis (AR) group as positive control, MPI group, negative control group and blank control group...
December 26, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29273990/distribution-contamination-and-accumulation-of-heavy-metals-in-water-sediments-and-freshwater-shellfish-from-liuyang-river-southern-china
#14
Yuyu Jia, Lin Wang, Zhipeng Qu, Zhaoguang Yang
Heavy metal distributions in water, sediments, and freshwater shellfish collected from Liuyang River in China have been investigated. The concentrations of heavy metals including Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Cd, and Pb were determined by ICP-MS. The distribution pattern of heavy metals in sediments was different from that in water. Large coefficients of variation of heavy metal concentrations were observed in water due to the susceptibility to discharge fluctuation and seasonal variation. Multivariate statistical analysis such as Pearson's correlation analysis, hierarchical cluster analysis (HCA), and principal component analysis (PCA) were employed to identify the possible sources of heavy metals in sediments...
December 22, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29273701/impact-of-nuclear-laboratory-personnel-credentials-continuing-education-on-nuclear-cardiology-laboratory-quality-operations
#15
Saurabh Malhotra, Diana M Sobieraj, April Mann, Matthew W Parker
Background/Objectives: The specific credentials and continuing education (CME/CE) of nuclear cardiology laboratory medical and technical staff are important factors in the delivery of quality imaging services that have not been systematically evaluated. Methods: Nuclear cardiology accreditation application data from the Intersocietal Accreditation Commission (IAC) was used to characterize facilities performing myocardial perfusion imaging by setting, size, previous accreditation and credentials of the medical and technical staff...
December 22, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/29258817/a-completely-reimplemented-mpi-bioinformatics-toolkit-with-a-new-hhpred-server-at-its-core
#16
Lukas Zimmermann, Andrew Stephens, Seung-Zin Nam, David Rau, Jonas Kübler, Marko Lozajic, Felix Gabler, Johannes Söding, Andrei N Lupas, Vikram Alva
The MPI Bioinformatics Toolkit (https://toolkit.tuebingen.mpg.de) is a free, one-stop web service for protein bioinformatic analysis. It currently offers 34 interconnected external and in-house tools, whose functionality covers sequence similarity searching, alignment construction, detection of sequence features, structure prediction, and sequence classification. This breadth has made the Toolkit an important resource for experimental biology and for teaching bioinformatic inquiry. Recently, we replaced the first version of the Toolkit, which was released in 2005 and had served around 2...
December 16, 2017: Journal of Molecular Biology
https://www.readbyqxmd.com/read/29258602/detection-of-prpbse-and-prion-infectivity-in-the-ileal-peyer-s-patch-of-young-calves-as-early-as-2%C3%A2-months-after-oral-challenge-with-classical-bovine-spongiform-encephalopathy
#17
Ivett Ackermann, Anne Balkema-Buschmann, Reiner Ulrich, Kerstin Tauscher, James C Shawulu, Markus Keller, Olanrewaju I Fatola, Paul Brown, Martin H Groschup
In classical bovine spongiform encephalopathy (C-BSE), an orally acquired prion disease of cattle, the ileal Peyer's patch (IPP) represents the main entry port for the BSE agent. In earlier C-BSE pathogenesis studies, cattle at 4-6 months of age were orally challenged, while there are strong indications that the risk of infection is highest in young animals. In the present study, unweaned calves aged 4-6 weeks were orally challenged to determine the earliest time point at which newly formed PrPBSE and BSE infectivity are detectable in the IPP...
December 19, 2017: Veterinary Research
https://www.readbyqxmd.com/read/29250434/the-relaxation-wall-experimental-limits-to-improving-mpi-spatial-resolution-by-increasing-nanoparticle-core-size
#18
Zhi Wei Tay, Daniel W Hensley, Erika C Vreeland, Bo Zheng, Steven M Conolly
Magnetic Particle Imaging (MPI) is a promising new tracer modality with zero attenuation in tissue, high contrast and sensitivity, and an excellent safety profile. However, the spatial resolution of MPI is currently around 1 mm in small animal scanners. Especially considering tradeoffs when scaling up MPI scanning systems to human size, this resolution needs to be improved for clinical applications such as angiography and brain perfusion. One method to improve spatial resolution is to increase the magnetic core size of the superparamagnetic nanoparticle tracers...
June 2017: Biomedical Physics & Engineering Express
https://www.readbyqxmd.com/read/29243071/assessment-of-left-ventricular-mass-by-spect-mpi
#19
EDITORIAL
René R Sevag Packard, Jamshid Maddahi
No abstract text is available yet for this article.
December 14, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29242496/assessment-of-fetal-myocardial-performance-index-in-women-with-placenta-previa
#20
Na Zhang, Lijuan Sun, Lina Zhang, Zhen Li, Jijing Han, Qingqing Wu
BACKGROUND This study investigated whether fetuses of placenta previa pregnancies have cardiac dysfunction by use of a modified myocardial performance index (Mod-MPI). MATERIAL AND METHODS A prospective cross-sectional study was conducted including 178 fetuses at 28-40 weeks of gestation. Eighty-nine fetuses of mothers with placenta previa and without pregnancy complications were recruited (placenta previa group) and matched with 89 fetuses of mothers with normal pregnancies (control group). Fetal cardiac function parameters and perinatal outcomes as well as the Mod-MPI were compared between the 2 groups...
December 15, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
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