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https://www.readbyqxmd.com/read/28944730/optimization-of-medication-use-at-accountable-care-organizations
#1
Chrisanne Wilks, Erik Krisle, Kimberly Westrich, Kristina Lunner, David Muhlestein, Robert Dubois
BACKGROUND: Optimized medication use involves the effective use of medications for better outcomes, improved patient experience, and lower costs. Few studies systematically gather data on the actions accountable care organizations (ACOs) have taken to optimize medication use. OBJECTIVES: To (a) assess how ACOs optimize medication use; (b) establish an association between efforts to optimize medication use and achievement on financial and quality metrics; (c) identify organizational factors that correlate with optimized medication use; and (d) identify barriers to optimized medication use...
October 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28944616/time-course-of-the-changes-in-right-and-left-ventricle-function-and-associated-factors-after-transcatheter-closure-of-atrial-septal-defects
#2
Byung W Yoo, Jung O Kim, Lucy Y Eun, Jae Y Choi, Dong S Kim
OBJECTIVE: The purpose of this study was to evaluate the changes in right ventricle (RV) and left ventricle (LV) function after transcatheter atrial septal defect (ASD) closure and to assess the influence of the age and the amount of shunt. DESIGN: Retrospective study PATIENTS: Fifty-three adult patients who underwent transcatheter closure were enrolled, then divided into subgroups according to the age (< 40 years vs ≥ 40 years), and the amount of shunt flow (QpQs < 2...
September 24, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28943706/theoretical-predictions-for-spatially-focused-heating-of-magnetic-nanoparticles-guided-by-magnetic-particle-imaging-field-gradients
#3
Rohan Dhavalikar, Carlos Rinaldi
Magnetic nanoparticles in alternating magnetic fields (AMFs) transfer some of the field's energy to their surroundings in the form of heat, a property that has attracted significant attention for use in cancer treatment through hyperthermia and in developing magnetic drug carriers that can be actuated to release their cargo externally using magnetic fields. To date, most work in this field has focused on the use of AMFs that actuate heat release by nanoparticles over large regions, without the ability to select specific nanoparticle-loaded regions for heating while leaving other nanoparticle-loaded regions unaffected...
December 1, 2016: Journal of Magnetism and Magnetic Materials
https://www.readbyqxmd.com/read/28942939/relation-of-coronary-flow-reserve-to-other-findings-on-positron-emission-tomography-myocardial-perfusion-imaging-and-left-heart-catheterization-in-patients-with-end-stage-renal-disease-being-evaluated-for-kidney-transplant
#4
Yehuda Paz, Rachelle Morgenstern, Richard Weinberg, Mariana Chiles, Navdeep Bhatti, Ziad Ali, Sumit Mohan, Sabahat Bokhari
Cardiovascular disease is the leading cause of death in patients with end-stage renal disease (ESRD) and often goes undetected. Abnormal coronary flow reserve (CFR), which predicts increased risk of cardiac death, may be present in patients with ESRD without other evidence of coronary artery disease (CAD). We prospectively studied 131 patients who had rest and dipyridamole pharmacologic stress N(13)-ammonia positron emission tomography myocardial perfusion imaging (PET MPI) for kidney transplant evaluation...
August 30, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28927447/protecting-effect-of-prp-codons-m142-and-k222-in-goats-orally-challenged-with-bovine-spongiform-encephalopathy-prions
#5
C Fast, W Goldmann, P Berthon, K Tauscher, O Andréoletti, I Lantier, C Rossignol, A Bossers, J G Jacobs, N Hunter, M H Groschup, F Lantier, J P M Langeveld
Breeding towards genetic resistance to prion disease is effective in eliminating scrapie. In sheep, classical forms of scrapie have been eradicated almost completely in several countries by breeding programs using a prion protein (PrP) gene (PRNP) amino acid polymorphism. For goats, field and experimental studies have provided evidence for several amino acid polymorphisms that are associated with resistance to scrapie, but only limited data are available concerning the susceptibility of caprine PRNP genotypes to BSE...
September 19, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28924814/the-prognostic-value-of-heart-rate-response-during-vasodilator-stress-myocardial-perfusion-imaging-in-patients-with-end-stage-renal-disease-undergoing-renal-transplantation
#6
Wael AlJaroudi, Chiedozie Anokwute, Ibtihaj Fughhi, Tania Campagnoli, Marwan Wassouf, Aviral Vij, Michael Kharouta, Andrew Appis, Amjad Ali, Rami Doukky
BACKGROUND: In asymptomatic end-stage renal disease (ESRD) patients undergoing vasodilator stress myocardial perfusion imaging (MPI) prior to renal transplantation (RT), the impact of pre-transplant heart rate response (HRR) to vasodilator stress on post-RT outcomes is unknown. METHODS: We analyzed a retrospective cohort of asymptomatic patients with ESRD who underwent a vasodilator stress SPECT-MPI and subsequently received RT. Blunted HRR was defined as HRR <28% for regadenoson stress and <20% for adenosine stress...
September 18, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28914830/-combined-forecasting-system-of-peritonitis-outcome
#7
N V Lebedev, A E Klimov, S B Agrba, E K Gaidukevich
AIM: To create a reliable system for assessing of severity and prediction of the outcome of peritonitis. MATERIAL AND METHODS: Critical analysis of the systems for peritonitis severity assessment is presented. The study included outcomes of 347 patients who admitted at the Department of Faculty Surgery of Peoples' Friendship University of Russia in 2015-2016. The cause of peritonitis were destructive forms of acute appendicitis, cholecystitis, perforated gastroduodenal ulcer, various perforation of small and large intestines (including tumor)...
2017: Khirurgiia
https://www.readbyqxmd.com/read/28906538/nuclear-cardiology-practices-and-radiation-exposure-in-africa-results-from-the-iaea-nuclear-cardiology-protocols-study-incaps
#8
Salah E Bouyoucef, Mathew Mercuri, Thomas N Pascual, Adel H Allam, Mboyo Vangu, João V Vitola, Nathan Better, Ganesan Karthikeyan, John J Mahmarian, Madan M Rehani, Ravi Kashyap, Maurizio Dondi, Diana Paez, Andrew J Einstein
OBJECTIVE: While nuclear myocardial perfusion imaging (MPI) offers many benefits to patients with known or suspected cardiovascular disease, concerns exist regarding radiation-associated health effects. Little is known regarding MPI practice in Africa. We sought to characterise radiation doses and the use of MPI best practices that could minimise radiation in African nuclear cardiology laboratories, and compare these to practice worldwide. METHODS: Demographics and clinical characteristics were collected for a consecutive sample of 348 patients from 12 laboratories in six African countries over a one-week period from March to April 2013...
July 2017: Cardiovascular Journal of Africa
https://www.readbyqxmd.com/read/28905123/no-difference-between-manual-and-different-power-toothbrushes-with-and-without-specific-instructions-in-young-oral-healthy-adults-results-of-a-randomized-clinical-trial
#9
Gerhard Schmalz, Katharina Kiehl, Jan Schmickler, Sven Rinke, Jana Schmidt, Felix Krause, Rainer Haak, Dirk Ziebolz
BACKGROUND: The aim of this randomized clinical study was to detect the effect of an instruction within a group using oscillating-rotating (OR), sonic-active (SA), or manual toothbrushes (MTB) in young, oral healthy adults. METHODS: One hundred fifty participants were randomly assigned into six groups (n = 25): with (OR-I, SA-I, MTB-I) and without instruction (OR-NI, SA-NI, MTB-NI). Participants in I subgroups received one standardized instruction of the toothbrush system...
September 13, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28902766/future-cardiac-events-in-patients-with-ischemic-ecg-changes-during-adenosine-infusion-as-a-myocardial-stress-agent-and-normal-cardiac-scan
#10
Hamid Amer, Khalid Niaz, Jun Hatazawa, Ahmed Gasmelseed, Hussain Al Samiri, Maram Al Othman, Mai Al Hammad
BACKGROUND: We sought to determine the prognostic importance of adenosine-induced ischemic ECG changes in patients with normal single-photon emission computed tomography myocardial perfusion images (MPI). PATIENTS AND METHODS: We carried out a retrospective analysis of 765 patients undergoing adenosine MPI between January 2013 and January 2015. Patients with baseline ECG abnormalities and/or abnormal scan were excluded. RESULTS: Overall, 67 (8...
September 11, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28899764/iron-oxide-core-oil-in-water-nanoemulsion-as-tracer-for-atherosclerosis-mpi-and-mri-imaging
#11
Geoffrey Prévot, Tina Kauss, Cyril Lorenzato, Alexandra Gaubert, Mélusine Larivière, Julie Baillet, Jeanny Laroche-Traineau, Marie Josée Jacobin-Valat, Laurent Adumeau, Stéphane Mornet, Philippe Barthélémy, Martine Duonor-Cérutti, Gisèle Clofent-Sanchez, Sylvie Crauste-Manciet
PURPOSE: For early atherosclerosis imaging, magnetic oil-in-water nanoemulsion (NE) decorated with atheroma specific monoclonal antibody was designed for Magnetic Particle Imaging (MPI) and Magnetic Resonance Imaging (MRI). MPI is an emerging technique based on direct mapping of superparamagnetic nanoparticles which may advantageously complement MRI. METHODS: NE oily droplets were loaded with superparamagnetic iron oxide nanoparticles of 7, 11 and 18nm and biofunctionalized with atheroma specific scFv-Fc TEG4-2C antibody...
September 9, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28895173/cardiac-changes-in-moderately-malnourished-children-and-their-correlations-with-anthropometric-and-electrolyte-changes
#12
Osama El Razaky, Ahmed Naeem, Amr Donia, Doaa El Amrousy, Noha Elfeky
OBJECTIVE: To evaluate electrocardiographic and echocardiographic changes in moderately malnourished children and to correlate them with both anthropometric and electrolyte changes. PATIENTS AND METHOD: Sixty moderately malnourished children were taken as patient group, and 60 healthy children of matched age and sex were taken as control group. Weight, height, body mass index (BMI), serum albumin, and electrolytes were measured for all children. Electrocardiographic evaluation for calculated QT (QTc) and QT dispersion (QTd) was performed...
September 12, 2017: Echocardiography
https://www.readbyqxmd.com/read/28893266/myocardial-performance-index-in-female-athletes
#13
Zahraa Alsafi, Andreas Malmgren, Petri Gudmundsson, Martin Stagmo, Magnus Dencker
BACKGROUND: Long-term intensive training leads to morphological and mechanical changes in the heart generally known as "athlete's heart". Previous studies have suggested that the diastolic and systolic function of the ventricles is unaltered in athletes compared to sedentary. The purpose of this study was to investigate myocardial performance index (MPI) by pulsed wave Doppler (PWD) and by tissue Doppler imaging (TDI) in female elite athletes compared to sedentary controls. METHODS: The study consisted of 32 athletes (mean age 20 ± 2 years) and 34 sedentary controls (mean age 23 ± 2 years)...
September 11, 2017: Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/28890492/a-quantitative-analysis-of-an-oil-component-in-an-emulsion-by-multiphoton-ionization-mass-spectrometry
#14
Hirofumi Fukaya, Tomohiro Uchimura
The first quantitative analysis of an oil component in an emulsion was achieved by multiphoton ionization time-of-flight mass spectrometry (MPI-TOFMS). An oil-in-water (O/W) emulsion was prepared. Styrene (0 - 5000 ng μL(-1)) and Triton X-100 were used as the oil phase and the disperser, respectively. Toluene was employed as an internal standard. We obtained a series of mass spectra, and then constructed the time profiles for styrene and toluene. As a result, we found several spikes from both time profiles when measuring emulsions with higher concentrations of styrene...
2017: Analytical Sciences: the International Journal of the Japan Society for Analytical Chemistry
https://www.readbyqxmd.com/read/28888406/temporal-trends-in-the-prevalence-severity-and-localization-of-myocardial-ischemia-and-necrosis-at-myocardial-perfusion-imaging-after-myocardial-infarction
#15
Francesco Nudi, Orazio Schilllaci, Natale Di Belardino, Francesco Versaci, Fabrizio Tomai, Annamaria Pinto, Giandomenico Neri, Enrica Procaccini, Alessandro Nudi, Giacomo Frati, Giuseppe Biondi-Zoccai
The definition, presentation, and management of myocardial infarction (MI) have changed substantially in the last decade. Whether these changes have impacted on the presence, severity, and localization of necrosis at myocardial perfusion imaging (MPI) has not been appraised to date. Subjects undergoing MPI and reporting a history of clinical MI were shortlisted. We focused on the presence, severity, and localization of necrosis at MPI with a retrospective single-center analysis. A total of 10,476 patients were included, distinguishing 5 groups according to the period in which myocardial perfusion scintigraphy had been performed (2004 to 2005, 2006 to 2007, 2008 to 2009, 2010 to 2011, 2012 to 2013)...
August 24, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28881987/efficient-simulation-of-intrinsic-extrinsic-and-external-noise-in-biochemical-systems
#16
Dennis Pischel, Kai Sundmacher, Robert J Flassig
Motivation: Biological cells operate in a noisy regime influenced by intrinsic, extrinsic and external noise, which leads to large differences of individual cell states. Stochastic effects must be taken into account to characterize biochemical kinetics accurately. Since the exact solution of the chemical master equation, which governs the underlying stochastic process, cannot be derived for most biochemical systems, approximate methods are used to obtain a solution. Results: In this study, a method to efficiently simulate the various sources of noise simultaneously is proposed and benchmarked on several examples...
July 15, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28866488/radiation-dose-reduction-in-ct-myocardial-perfusion-imaging-using-smart-recon
#17
Yinsheng Li, Michael A Speidel, Christopher J Francois, Guang-Hong Chen
In this work, a newly developed statistical model based image reconstruction (referred to as Simultaneous Multiple Artifacts Reduction in Tomographic RECONstruction (SMARTRECON) [1]) is applied to low dose computer tomography (CT) myocardial perfusion imaging (CT-MPI). This method uses the nuclear norm of the spatial-temporal image matrix of the CTMPI images as a regularizer, rather than a conventional spatial regularizer that incorporates image smoothness, edge preservation, or spatial sparsity into the reconstruction...
August 30, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28865679/quantification-of-myocardial-perfusion-reserve-using-dynamic-spect-images-of-patients-with-chronic-kidney-disease
#18
Noriko Tsuda, Shinya Shiraishi, Fumi Sakamoto, Hideaki Yuki, Koji Ogasawara, Morikatsu Yoshida, Seiji Tomiguchi, Kenichi Tsujita, Yasuyuki Yamashita
BACKGROUND: Chronic kidney disease (CKD) is an independent risk factor for cardiovascular disorders. The aim of this study was to examine whether the quantitatively measured myocardial blood flow (MBF) or myocardial perfusion reserve (MPR), calculated by dynamic single photon emission computed tomography (SPECT) analysis using a cardiac cadmium zinc telluride (CZT) gamma camera, was related to renal dysfunction in patients with normal myocardial perfusion imaging (MPI) findings. METHODS: The study population consisted of 46 patients with CKD and 46 individuals without CKD (controls)...
August 30, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28852232/characteristics-of-patients-with-high-lie-scores-in-a-personality-test
#19
Yuichi Kasai, Toshihiko Sakakibara, Tetsutaro Mizuno
BACKGROUND: It is reported that persons with high Lie score (L score) of a personality test are aggressively self-confident and are also related to depression or schizophrenia In this study, we examined the characteristics of patients with high L scores on the Maudsley Personality Inventory (MPI) and examined the significance of the L score. MATERIALS AND METHODS: We collected the data of 10789 subjects and examined the relationship between L score or the number of characteristic biased persons and the parameters of age, sex, education level, occupation, and degree of pain...
July 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28845539/long-term-outcomes-of-narrow-diameter-implants-in-posterior-jaws-a-retrospective-study-with-at-least-8-year-follow-up
#20
Jun-Yu Shi, Feng-Yuan Xu, Long-Fei Zhuang, Ying-Xin Gu, Shi-Chong Qiao, Hong-Chang Lai
OBJECTIVE: The aim of this study was to evaluate the long-term survival, complications, peri-implant conditions, marginal bone loss, and patient satisfaction of fixed dental prostheses supported by narrow diameter implants (NDIs) in the posterior jaws. MATERIALS AND METHODS: This study was designed as a retrospective cohort study with a mean follow-up time of 10.1 years (SD: 2.5 years). Patients receiving NDIs in posterior jaw were reviewed. Implant survival, hardware complication, modified plaque index (mPI), peri-implant probing depth (PPD), percentage of bleeding on probing (BOP%), marginal bone loss (MBL), and patient satisfaction were evaluated...
August 28, 2017: Clinical Oral Implants Research
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