keyword
https://read.qxmd.com/read/38545037/association-of-epicardial-fat-volume-with-subclinical-myocardial-damage-in-patients-with-type-2-diabetes-mellitus
#1
JOURNAL ARTICLE
Yurui Hu, Wenji Yu, Feifei Zhang, Yufeng Wang, Jingwen Wang, Peng Wan, Xiaoliang Shao, Jianfeng Wang, Yonghong Sun, Yuetao Wang
BACKGROUND: In type 2 diabetes mellitus (T2DM) patients, left ventricular systolic dyssynchrony (LVSD) with normal left ventricular ejection fraction (LVEF) and normal myocardial perfusion could referred to as subclinical myocardial damage, which is difficult to diagnose at an early stage. Epicardial adipose tissue, a distinctive heart-specific visceral fat, is closely related to various cardiovascular diseases. The objective of this study was to investigate the correlation between epicardial fat volume (EFV) and subclinical myocardial damage in T2DM patients...
March 15, 2024: Quantitative Imaging in Medicine and Surgery
https://read.qxmd.com/read/38543373/study-of-the-dielectric-and-corona-resistance-properties-of-pi-films-modified-with-fluorene-moiety-aluminum-sec-butoxide
#2
JOURNAL ARTICLE
Changhai Zhang, Ziyang Liu, Chao Tang, Tiandong Zhang, Yue Zhang, Yongquan Zhang, Qingguo Chi
With the policy tilt and increased investment in research and development in the world, new energy vehicle technology continues to progress and the drive motor power density continues to improve, which puts forward higher requirements for the comprehensive performance of the core insulating material enameled wire enamel for drive motors. Polyimide (PI) has excellent electrical insulation properties, and heat resistance is often used to drive the motor winding insulation. To further improve the corona resistance and insulating properties of PI wire enamel varnish, in this paper, firstly, fluorene groups with a rigid conjugated structure were introduced into the molecular chain of the PI film by molecular structure modulation, and then uniformly dispersed alumina nanoclusters (AOCs) were introduced into the PI matrix by using an in situ growth process to inhibit the migration of high-energy electrons...
March 11, 2024: Polymers
https://read.qxmd.com/read/38543086/magnetic-hyperthermia-therapy-for-high-grade-glioma-a-state-of-the-art-review
#3
REVIEW
Benjamin Rodriguez, Daniel Rivera, Jack Y Zhang, Cole Brown, Tirone Young, Tyree Williams, Sakibul Huq, Milena Mattioli, Alexandros Bouras, Constantinos G Hadjpanayis
Magnetic hyperthermia therapy (MHT) is a re-emerging treatment modality for brain tumors where magnetic nanoparticles (MNPs) are locally delivered to the brain and then activated with an external alternating magnetic field (AMF) to generate localized heat at a site of interest. Due to the recent advancements in technology and theory surrounding the intervention, clinical and pre-clinical trials have demonstrated that MHT may enhance the effectiveness of chemotherapy and radiation therapy (RT) for the treatment of brain tumors...
February 26, 2024: Pharmaceuticals
https://read.qxmd.com/read/38538067/a-new-doppler-index-cerebro-placental-uterine-ratio-and-fetal-cardiac-parameters-in-early-onset-preeclampsia
#4
JOURNAL ARTICLE
Yüksel Oğuz, Recep Taha Ağaoğlu, Can Ozan Ulusoy, Özge Öztürk, İzzet Özgürlük, Çağanay Soysal, Zehra Yılmaz Vural, Kadriye Yakut Yücel
OBJECTIVE: Our aim was to investigate the significance of cerebro-placento-uterine ratio CPUR, a new Doppler index, and fetal cardiac parameters (Mod MPI, EFT) in early-onset preeclampsia (EOPE) and to examine whether these parameters are related to perinatal outcome. STUDY DESIGN: Forty participants diagnosed with EOPE (preeclampsia cases diagnosed before 34 weeks of gestation) and 40 healthy pregnant women were included in this study. Demographic data were recorded...
March 27, 2024: Journal of Clinical Ultrasound: JCU
https://read.qxmd.com/read/38535946/riparian-soil-pollution-caused-by-sediment-metal-transport-seasonal-changes-and-ecological-risk-assessment
#5
JOURNAL ARTICLE
Ahmet Çelebi, Bülent Şengörür, Ali Torabi Haghighi, Ali Danandeh Mehr
The accumulation of pollutants in the sediment along surface water may negatively affect riparian zones and increase ecological risk. This article investigates the effects of metal sediments on riparian soil via field monitoring and ICP-OES analysis. To this end, pollution levels, seasonal changes, and potential sources of the pollutants were determined for the Melen River watershed, Turkey. The ecological statuses (contamination factor, enrichment factor, index of geo-accumulation, pollution index, modified pollution index, and potential and modified ecological risk indexes) of the watershed were also analyzed...
March 13, 2024: Toxics
https://read.qxmd.com/read/38531998/is-there-an-advantage-to-delayed-molar-implant-placement-in-those-with-chronic-apical-periodontitis
#6
JOURNAL ARTICLE
Rabab Ahmad
DESIGN: This paper is a single-centre, double-blinded, prospective randomised control trial, comparing immediate vs delayed implant placement clinically and radiographically in patients with chronic periodontitis, specifically assessing the molar region. Seventy-four patients were recruited to the study over a one-year period, all of whom returned for follow up throughout the study. STUDY SELECTION: The study adhered to the principles outlined in the Declaration of Helsinki and obtained ethical approval from the affiliated University Hospital of Qingdao...
March 26, 2024: Evidence-based Dentistry
https://read.qxmd.com/read/38530609/changes-in-cardiac-functions-in-patients-treated-with-parathyroidectomy-for-secondary-hyperparathyroidism
#7
JOURNAL ARTICLE
Sami Benli, Emrah Yesil, Deniz Tazeoglu, Cumhur Ozcan, Ismail Turkay Ozcan, Ahmet Dag
Our study aims to investigate the changes in cardiac functions, especially myocardial performance index (MPI), in patients who underwent parathyroidectomy for secondary hyperparathyroidism. Patients who underwent parathyroidectomy for secondary hyperparathyroidism between June 2010 and September 2021 were analyzed retrospectively. The patients were divided into two groups: those who underwent total parathyroidectomy (group 1) and those who underwent subtotal parathyroidectomy (group 2). The groups were compared according to the echocardiogram findings performed in the preoperative period and the postoperative sixth month...
March 26, 2024: Updates in Surgery
https://read.qxmd.com/read/38525588/the-prognostic-value-of-visual-and-automatic-coronary-calcium-scoring-from-low-dose-ct-15o-water-pet
#8
JOURNAL ARTICLE
M M Dobrolinska, R A Jukema, S G M van Velzen, P A van Diemen, M J W Greuter, N H J Prakken, N R van der Werf, P G Raijmakers, R H J A Slart, P Knaapen, I Isgum, I Danad
PURPOSE: Firstly, to validate automatically and visually scored coronary artery calcium (CAC) on low dose CT (LDCT) scans with a dedicated calcium scoring CT (CSCT) scan. Secondly, to assess the added value of CAC scored from LDCT scans acquired during [15O]-water-PET myocardial perfusion imaging (MPI) on prediction of major adverse cardiac events (MACE). METHODS: 572 consecutive patients with suspected coronary artery disease, who underwent [15O]-water-PET MPI with LDCT and a dedicated CSCT scan were included...
March 25, 2024: European Heart Journal Cardiovascular Imaging
https://read.qxmd.com/read/38521708/artificial-intelligence-in-nuclear-cardiology-an-update-and-future-trends
#9
REVIEW
Robert J H Miller, Piotr J Slomka
Myocardial perfusion imaging (MPI), using either single photon emission computed tomography (SPECT) or positron emission tomography (PET), is one of the most commonly ordered cardiac imaging tests, with prominent clinical roles for disease diagnosis and risk prediction. Artificial intelligence (AI) could potentially play a role in many steps along the typical MPI workflow, from image acquisition through to clinical reporting and risk estimation. AI can be utilized to improve image quality, reducing radiation exposure and image acquisition times...
March 22, 2024: Seminars in Nuclear Medicine
https://read.qxmd.com/read/38518887/how-to-assess-non-responsiveness-to-vasodilator-stress
#10
JOURNAL ARTICLE
Phillip Lim, Vikram Agarwal, Krishna K Patel
Myocardial perfusion imaging (MPI) is a powerful tool for the functional assessment of ischemia in patients with suspected or known coronary artery disease (CAD). Given that the diagnostic accuracy and prognostic value of MPI and post-test management are highly dependent on achieving an adequate stress vasodilatory response, it is critical to identify those who may not have adequately responded to vasodilator pharmacological stress agents such as adenosine, dipyridamole, and regadenoson. Caffeine, a potent inhibitor of the adenosine receptor, is a compound that can affect vasodilatory hemodynamics, result in false negative studies, and potentially alter management in cases of inaccurate test results...
March 20, 2024: Journal of Nuclear Cardiology
https://read.qxmd.com/read/38514280/closed-sinus-lift-and-fixed-prostheses-versus-implant-assisted-overdentures-in-management-of-atrophied-distal-extension-maxillary-ridges-a-one-year-randomized-clinical-trial
#11
JOURNAL ARTICLE
Khalid Ali Abd-Elmoneam Khorshed, Mohamed Elgamal, Mai Ahmed Haggag, Moustafa Abdou ELsyad
STATEMENT OF PROBLEM: Rehabilitation of elderly or medically compromised patients with an atrophied unilateral posterior maxillary ridge by an implant-supported prosthesis may be complicated by maxillary sinus pneumatization with insufficient bone for implant placement. PURPOSE: This short-term clinical trial assessed clinical results of closed sinus lift and fixed prosthesis versus implant-assisted overdentures in the management of participants with atrophied distal extension maxillary ridges...
March 20, 2024: Journal of Prosthetic Dentistry
https://read.qxmd.com/read/38512452/elevated-uptake-and-translocation-patterns-of-heavy-metals-in-different-food-plants-parts-and-their-impacts-on-human-health
#12
JOURNAL ARTICLE
Md Abdul Goni, Lokman Hosen, Abu Shamim Khan, M Abdullah-Al-Mamun, Most Johura Khatun, Tasneem Siddiquee
Irrigation with contaminated wastewater is a common practice in cultivation of crops and vegetables in many developing countries due to the scarcity of available fresh water. The present study has investigated the transfer and mobilization trends of heavy metals in different crops and vegetables plants grown in contaminated soil and waterbody. The translocation patterns of metals from polluted sources into different organs of plants bodies such as roots and edible parts and associated health risks have been evaluated simultaneously...
March 21, 2024: Biological Trace Element Research
https://read.qxmd.com/read/38510504/myocardial-perfusion-imaging-derived-left-ventricular-strain-regional-abnormalities-associated-with-transthyretin-cardiac-amyloidosis
#13
JOURNAL ARTICLE
Steven Lewis, Jingwen Huang, Nidhi Patel, Russell Folks, James Galt, C David Cooke, Ziduo Zheng, Rebecca Zhang, Ernest Garcia, Jonathon Nye, Marina Piccinelli, Valeria Moncayo, Kunal Bhatt, Adam Mitchell
BACKGROUND: Transthyretin (ATTR) cardiac amyloidosis is associated with an apical-sparing strain pattern on TTE. We hypothesize that strain indices derived from myocardial perfusion imaging (MPI) can identify this abnormality. METHODS: A group with ATTR amyloidosis was compared to age-matched controls with LVH but without amyloidosis who underwent PET or SPECT MPI. Strain values were used to calculate the apical strain index (ASI), apex-to-base ratio (ABR), and ejection fraction to global strain ratio in multiple planes...
April 2024: American heart journal plus: cardiology research and practice
https://read.qxmd.com/read/38503305/fetal-epicardial-fat-thickness-in-obese-pregnant-women-its-effect-on-fetal-cardiac-function-and-neonatal-outcomes
#14
Şükran Doğru, Fatih Akkuş, Ülfet Sena Metin, Ali Acar
OBJECTIVE: This study aimed to evaluate fetal epicardial fat thickness (EFT) together with fetal myocardial performance index (MPI) and its effects on neonatal outcomes in obese pregnant women. MATERIALS AND METHODS: A total of 102 pregnant women, 51 obese and 51 of normal weight, were included in this prospective study. Fetal EFT, and MPI measurements were performed for all patients. RESULTS: Fetal EFT and Mod-MPI showed a statistically significant difference between obese pregnant women and the control group (p=0...
March 19, 2024: Zeitschrift Für Geburtshilfe und Neonatologie
https://read.qxmd.com/read/38502462/novel-indices-representing-heterogeneous-distributions-of-myocardial-perfusion-imaging
#15
JOURNAL ARTICLE
Misato Chimura, Tomohito Ohtani, Fusako Sera, Rie Higuchi, Kenji Kajitani, Kenichi Nakajima, Yasushi Sakata
INTRODUCTION: Heterogeneous distribution in myocardial perfusion images (MPI) obtained by scintigraphy is often observed in cardiac diseases with normal myocardial perfusion. However, quantitative assessments of such heterogeneity have not been established. We hypothesized that the heterogeneity in MPI can be quantitatively evaluated through histogram analysis, calculating the standard deviation (SD), the 95% bandwidth (BW95%), and entropy. METHODS: We examined resting 99m Tc-MIBI images in 20 healthy subjects and 29 patients with cardiac disease who had none or very-mild reduced myocardial perfusion evaluated as a low summed rest score (0 to 4, the range of the studied healthy subjects)...
March 19, 2024: Annals of Nuclear Medicine
https://read.qxmd.com/read/38499713/anatomic-total-shoulder-predictors-of-excellent-outcomes-at-five-years-after-arthroplasty
#16
JOURNAL ARTICLE
Zachary D Mills, Corey J Schiffman, Behnam Sharareh, Anastasia J Whitson, Frederick A Matsen, Jason E Hsu
PURPOSE: The objectives of this study were to: report minimum 5-year outcomes in patients undergoing TSA and determine characteristics predictive of patients achieving an excellent functional outcome. METHODS: Pre-operative demographic variables and Simple Shoulder Test (SST) scores were obtained pre-operatively and at a minimum of five years after surgery. A final SST ≥ 10 and percentage of maximal possible improvement (% MPI) of ≥ 66...
March 19, 2024: International Orthopaedics
https://read.qxmd.com/read/38498750/a-novel-local-magnetic-fluid-hyperthermia-based-on-high-gradient-field-guided-by-magnetic-particle-imaging
#17
JOURNAL ARTICLE
Siao Lei, Jie He, Xiazi Huang, Hui Hui, Yu An, Jie Tian
Magnetic Particle Imaging (MPI)-guided Magnetic Fluid Hyperthermia (MFH) has the potential for widespread utilization, as it allows for the prediction of magnetothermal dosage, real-time visualization of the thermal therapy process, and precise localization of the lesion area. However, the existing MPI-guided MFH (MPI-MFH) method is insensitive to concentration gradients of magnetic nanoparticles (MNPs) and is susceptible to causing damage to normal tissues with high MNP concentrations during MFH treatment, while inadequately heating tumor tissues with lower MNP concentrations...
March 18, 2024: IEEE Transactions on Bio-medical Engineering
https://read.qxmd.com/read/38497864/independent-predictors-of-true-positivity-of-positive-myocardial-perfusion-imaging
#18
JOURNAL ARTICLE
F Koca, G Özmen
UNLABELLED: OBJECTIVE: The primary aim of the present study was to determine the success of single-photon emission computed tomography myocardial perfusion imaging (SPECT-MPI) in detecting critical coronary artery disease (CAD) as identified by invasive coronary angiography (ICA), as well as to compare the positive predictive values (PPV) of different stress methods. Our secondary aim was to investigate demographic, laboratory, electrocardiographic, and echocardiographic variables that could predict true positive results...
March 2024: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/38494979/-effect-of-gingival-biotype-on-total-crown-repair-and-gingival-crevicular-fluid-inflammatory-factors
#19
JOURNAL ARTICLE
Yun Gai, Zhi-Ming Liu, Shen Zeng
PURPOSE: To explore the effect of thick and thin sputum on the restoration of oral anterior teeth and the index of gingival crevicular fluid. METHODS: A study was conducted on 80 patients (130 teeth) who underwent full-ceramic crown treatment for anterior tooth restoration in Jiangnan University Affiliated Hospital 's oral clinic. The patients were divided into thick gingival type (42 cases, 67 teeth) and thin gingival type (38 cases, 63 teeth) according to their gingival biotype...
December 2023: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://read.qxmd.com/read/38493608/establishment-of-a-human-induced-pluripotent-stem-cell-line%C3%AF-sdqlchi059-a%C3%AF-from-a-patient-with-congenital-disorder-of-glycosylation-carrying-heterozygous-mutation-in-mpi-gene
#20
JOURNAL ARTICLE
Bin Wang, Lu Yang, Min Gao, Haiyan Zhang, Yi Liu, Zhongtao Gai
Congenital disorder of glycosylation (CDG) is inherited metabolicdiseasecaused by defects in the genes important for the process of protein and lipidglycosylation. We established an induced pluripotent stem cell (iPSC) line from peripheral blood mononuclear cells of a 6-month-old boy with congenital disorder of glycosylation carrying heterozygous mutations c.1193 T > C (p.I398T) and c.376_384dup CCGCAGCAC (p.P126_H128 dupPQH) in MPI gene. This iPSC line was free of exogenous gene, expressed pluripotency markers, has normal karyotype, exhibited differentiation potential and harbored the same mutations found in the patient...
March 8, 2024: Stem Cell Research
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