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https://www.readbyqxmd.com/read/28723467/human-papillomavirus-infection-and-vaccination-in-males
#1
REVIEW
Eugenio Ventimiglia, Simon Horenblas, Asif Muneer, Andrea Salonia
CONTEXT: Human papillomavirus (HPV) is the commonest sexually transmitted pathogen in humans and is linked to the aetiopathogenesis for both benign and malignant disease in men. OBJECTIVE: To evaluate and summarise the evidence for HPV infection and vaccination in men. EVIDENCE ACQUISITION: A search of Medline, PubMed, and Scopus was performed to identify articles published in English within the last 10 yr addressing HPV epidemiology, the natural history of HPV infection and its long-term consequences, and vaccination in men...
October 2016: European Urology Focus
https://www.readbyqxmd.com/read/28711469/targeting-weight-loss-interventions-to-reduce-cardiovascular-complications-of-type-2-diabetes-a-machine-learning-based-post-hoc-analysis-of-heterogeneous-treatment-effects-in-the-look-ahead-trial
#2
Aaron Baum, Joseph Scarpa, Emilie Bruzelius, Ronald Tamler, Sanjay Basu, James Faghmous
BACKGROUND: The Action for Health in Diabetes (Look AHEAD) trial investigated whether long-term cardiovascular disease morbidity and mortality could be reduced through a weight loss intervention among people with type 2 diabetes. Despite finding no significant reduction in cardiovascular events on average, it is possible that some subpopulations might have derived benefit. In this post-hoc analysis, we test the hypothesis that the overall neutral average treatment effect in the trial masked important heterogeneous treatment effects (HTEs) from intensive weight loss interventions...
July 12, 2017: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/28710305/autism-spectrum-disorder-in-say-barber-biesecker-young-simpson-syndrome
#3
Jessica Merritt, Joseph C Hart, Tracy L LeGrow
Say-Barber-Biesecker-Young-Simpson syndrome (SBBYSS), also known as Ohdo syndrome SBBYS type, is a rare genetic disorder characterised by dysmorphic facial features and severe intellectual disability, as well as cardiac, dental and hearing abnormalities. There has been little psychiatric or psychological description of children with SBBYSS, although previous reports noted repetitive self-injurious behaviours, sensitivity to light and noise and severe deficits in communication. In this report, a 4-year-old male with SBBYSS is described with a focus on psychiatric and psychological assessment, including formal testing for autism spectrum disorder (ASD)...
July 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28703926/difficult-conversations-adults-with-diabetes-and-the-discussion-of-microvascular-complications
#4
M D Ritholz, T MacNeil, K Weinger
AIMS: To investigate the experiences among adults with diabetes of discussions of microvascular complications and provide recommendations for providers. METHODS: We performed a qualitative study in 148 adults with Type 1 and Type 2 diabetes (56% women, 95% white, mean age 60±13 years, 65% with Type 1 diabetes, 71% with ≥1 microvascular complication). Data were analysed using content analysis. RESULTS: At their first discussion of microvascular complications, 93% of participants (138/148) recalled providers using a preventative approach including clinical suggestions, factual information and warnings...
July 13, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28701492/behavioral-variant-frontotemporal-dementia-distinct-phenotypes-with-unique-functional-profiles
#5
Claire M O'Connor, Ramon Landin-Romero, Lindy Clemson, Cassandra Kaizik, Naomi Daveson, John R Hodges, Sharpley Hsieh, Olivier Piguet, Eneida Mioshi
OBJECTIVE: To identify distinct behavioral phenotypes of behavioral-variant frontotemporal dementia (bvFTD) and to elucidate differences in functional, neuroimaging, and progression to residential care placement. METHODS: Eighty-eight patients with bvFTD were included in a cluster analysis applying levels of disinhibition and apathy (Cambridge Behavioural Inventory-Revised) to identify phenotypic subgroups. Between-group (Kruskal-Wallis, Mann-Whitney U) functional differences (Disability Assessment for Dementia) and time to residential care placement (survival analyses) were examined...
July 12, 2017: Neurology
https://www.readbyqxmd.com/read/28695931/methods-of-protein-corona-isolation-for-magnetic-nanoparticles
#6
Debora Bonvin, Diego Chiappe, Marc Moniatte, Heinrich Hofmann, Marijana Mionić Ebersold
Nanoparticles (NPs) in contact with a biological environment get covered by proteins and some are loosely bound and some are tightly bound. The latter form a hard protein corona (HPC) which is known to determine their biological behavior. Therefore, in order to study the biological behaviour of NPs one needs to start from the HPC. However, established methods and standards of HPC isolation are still not known. This is especially a challenge in the case of magnetic NPs which form a major branch of nanomedicine...
July 11, 2017: Analyst
https://www.readbyqxmd.com/read/28695705/all-drinking-is-not-equal-how-a-social-practice-theory-lens-could-enhance-public-health-research-on-alcohol-and-other-health-behaviours
#7
Petra Sylvia Meier, Alan Warde, John Holmes
BACKGROUND: The social meanings, settings and habitual nature of health-related activities and their integration into our daily lives are often overlooked in quantitative public health research. This reflects an overly individualized approach to epidemiological surveillance and evaluations of public health interventions, based on models of behaviour that are rooted in social cognition and rational choice theories. This paper calls for a new approach to alcohol epidemiology and intervention research informed by theories of practice...
July 11, 2017: Addiction
https://www.readbyqxmd.com/read/28693473/building-copd-care-on-shaky-ground-a-mixed-methods-study-from-swedish-primary-care-professional-perspective
#8
Sara Lundell, Malin Tistad, Börje Rehn, Maria Wiklund, Åsa Holmner, Karin Wadell
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a public health problem. Interprofessional collaboration and health promotion interventions such as exercise training, education, and behaviour change are cost effective, have a good effect on health status, and are recommended in COPD treatment guidelines. There is a gap between the guidelines and the healthcare available to people with COPD. The aim of this study was to increase the understanding of what shapes the provision of primary care services to people with COPD and what healthcare is offered to them from the perspective of healthcare professionals and managers...
July 10, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28688399/a-circularisation-method-to-repair-deformations-and-determine-the-centre-of-velocity-map-images
#9
Jason R Gascooke, Stephen T Gibson, Warren D Lawrance
A problem besetting the analysis of velocity map images, particularly those of photoelectrons, is the presence of distortions that cause the features in the image to deviate from circularity, leading to a loss of resolution in the spectrum extracted. A method is presented to repair such distortions based on fitting the angular behaviour of each of the ring structures to a trigonometric expansion. The repair function allows the intensity at any value of radius and angle to be mapped to a new position that removes the distortion and returns the features to circular...
July 7, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28688334/-behind-closed-doors-with-open-minds-a-qualitative-study-exploring-nursing-home-staff-s-narratives-towards-their-roles-and-duties-within-the-context-of-sexuality-in-dementia
#10
T Vandrevala, T Chrysanthaki, E Ogundipe
BACKGROUND: Despite sexual expression being recognised as a fundamental human need, sexuality in old age is often ignored and frequently misunderstood, with residents with dementia in a nursing home often viewed as asexual or incapable of being sexually active. OBJECTIVES: The current study aims to understand the views held by nursing care home staff towards dementia and sexuality and explore the roles they may adopt whilst responding and managing sexual needs and expression for residents with dementia...
June 13, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28686072/expression-of-masculine-identity-in-individuals-with-a-traumatic-brain-injury
#11
Louise C Keegan, Leanne Togher, Macy Murdock, Emma Hendry
PRIMARY OBJECTIVE: This research seeks to examine and describe how four males with a traumatic brain injury (TBI) use language to negotiate their masculine identities. RESEARCH DESIGN: Qualitative research methods were employed with a 'case study' design that allows for a detailed description of the cases, and the interactions examined. METHODS AND PROCEDURES: The tools of inquiry applied included a topic analysis, as well as linguistic analysis methods that incorporated the theory of Systemic Functional Linguistics...
July 7, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28679423/electronic-health-record-portal-adoption-a-cross-country-analysis
#12
Jorge Tavares, Tiago Oliveira
BACKGROUND: This study's goal is to understand the factors that drive individuals to adopt Electronic Health Record (EHR) portals and to estimate if there are differences between countries with different healthcare models. METHODS: We applied a new adoption model using as a starting point the extended Unified Theory of Acceptance and Use of Technology (UTAUT2) by incorporating the Concern for Information Privacy (CFIP) framework. To evaluate the research model we used the partial least squares (PLS) - structural equation modelling (SEM) approach...
July 5, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28677909/processes-of-change-in-an-offender-personality-disorder-pathway-prison-progression-unit
#13
Mary McMurran, Steve Delight
BACKGROUND: In England, the National Offender Management Service and the NHS have come together to try and improve management and treatment of offenders with personality disorder by developing a pathways approach to assist high-risk male offenders with severe personality disorder. AIM: The aim of the study is to investigate service user and staff perceptions of change in this pathway. METHODS: Semi-structured interviews were conducted with 16 prisoners and 16 staff in one unit in a London-based personality disorder pathway...
July 2017: Criminal Behaviour and Mental Health: CBMH
https://www.readbyqxmd.com/read/28677828/vortioxetine-for-depression-in-adults
#14
REVIEW
Markus Koesters, Giovanni Ostuzzi, Giuseppe Guaiana, Johanna Breilmann, Corrado Barbui
BACKGROUND: Major depressive disorder is a common mental disorder affecting a person's mind, behaviour and body. It is expressed as a variety of symptoms and is associated with substantial impairment. Despite a range of pharmacological and non-pharmacological treatment options, there is still room for improvement of the pharmacological treatment of depression in terms of efficacy and tolerability. The latest available antidepressant is vortioxetine. It is assumed that vortioxetine's antidepressant action is related to a direct modulation of serotonergic receptor activity and inhibition of the serotonin transporter...
July 5, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28677689/brain-network-dynamics-in-high-functioning-individuals-with-autism
#15
Takamitsu Watanabe, Geraint Rees
Theoretically, autism should be underpinned by aberrant brain dynamics. However, how brain activity changes over time in individuals with autism spectrum disorder (ASD) remains unknown. Here we characterize brain dynamics in autism using an energy-landscape analysis applied to resting-state fMRI data. Whereas neurotypical brain activity frequently transits between two major brain states via an intermediate state, high-functioning adults with ASD show fewer neural transitions due to an unstable intermediate state, and these infrequent transitions predict the severity of autism...
July 5, 2017: Nature Communications
https://www.readbyqxmd.com/read/28676693/selective-breeding-and-selection-mapping-using-a-novel-wild-derived-heterogeneous-stock-of-mice-revealed-two-closely-linked-loci-for-tameness
#16
Yuki Matsumoto, Tatsuhiko Goto, Jo Nishino, Hirofumi Nakaoka, Akira Tanave, Toshiyuki Takano-Shimizu, Richard F Mott, Tsuyoshi Koide
Tameness is a major behavioral factor for domestication, and can be divided into two potential components: motivation to approach humans (active tameness) and reluctance to avoid humans (passive tameness). We identified genetic loci for active tameness through selective breeding, selection mapping, and association analysis. In previous work using laboratory and wild mouse strains, we found that laboratory strains were predominantly selected for passive tameness but not active tameness during their domestication...
July 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28676680/the-development-and-validation-of-the-addiction-like-eating-behaviour-scale
#17
H K Ruddock, P Christiansen, J C G Halford, C A Hardman
BACKGROUND: Overeating and obesity are frequently attributed to an addiction to food. However, there is currently a lack of evidence to support the idea that certain foods contain any specific addictive substance. An alternative approach is to focus on dimensions of observable behaviour which may underpin a behavioural addiction to eating. To facilitate this, it is necessary to develop a tool to quantify addiction-like eating behaviour that is not based on the clinical criteria for substance-dependence...
July 5, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28671588/implications-of-neuroinvasive-bacterial-peptides-on-rodents-behaviour-and-neurotransmission
#18
Aneela Taj, Nusrat Jamil
Neuroinvasive microbes are capable of applying their influences on the autonomic nervous system (ANS) of the host followed by the involvement of central nervous system (CNS) by releasing extracellular metabolites that may cause alterations in the biochemical and neurophysiological environment. Consequently synaptic, neuroendocrine, peripheral immune, neuro-immune, and behavioural responses of the host facilitate the progression of infection. The present study was designed to extrapolate the effects of crude and purified extracellular peptides of neuropathogenic bacteria on behavioural responses and neurotransmission of Sprague Dawley (SD) models...
July 2, 2017: Pathogens
https://www.readbyqxmd.com/read/28668642/thank-you-letters-from-patients-in-an-intensive-care-unit-from-the-expression-of-gratitude-to-an-applied-ethic-of-care
#19
Alexandre Herbland, Michel Goldberg, Nathalie Garric, Olivier Lesieur
INTRODUCTION: Patients' perception of an intensive care unit stay can lead to a better understanding of the expectations and needs of patients hospitalised in intensive care so that care for critically ill patients can be adapted and improved. Thank you letters are sources of original information which come directly and spontaneously from patients. OBJECTIVE: The objective of this study was to analyse the thank you letters from patients who required intensive care treatment and to identify messages that could be intended for the intensive care unit team...
June 28, 2017: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/28667824/the-association-between-personal-income-and-smoking-among-adolescents-a-study-in-six-european-cities
#20
J Perelman, J Alves, T Pfoertner, I Moor, B Federico, M A G Kuipers, M Richter, A Rimpela, A E Kunst, V Lorant
AIMS: This study investigates the link between personal income and smoking among adolescents, and aims to answer the following questions: (i) to what extent is personal income related to smoking, independent of family socioeconomic status (SES)? (ii) does the association between personal income and smoking apply to different sub-populations? DESIGN: Cross-sectional study. SETTING: Six cities from European countries (Amersfoort/Netherlands, Coimbra/Portugal, Hannover/Germany, Latina/Italy, Namur/Belgium, Tampere/Finland), in 2013...
July 1, 2017: Addiction
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