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https://www.readbyqxmd.com/read/28805528/pace-investigators-response-is-misleading-regarding-patient-survey-results
#1
Karen D Kirke
The PACE investigators' citation of a patient survey might mislead readers into thinking that the experience of people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) supports PACE findings. In fact, patient survey evidence directly contradicts the results of the PACE trial. A review of survey data published between 2001 and 2015 reveals that for most patients, graded exercise therapy leads to worsening of symptoms, cognitive behavioural therapy leads to no change in symptoms, and pacing leads to improvement...
August 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28805524/response-to-the-editorial-by-dr-geraghty
#2
Peter D White, Trudie Chalder, Michael Sharpe, Brian J Angus, Hannah L Baber, Jessica Bavinton, Mary Burgess, Lucy V Clark, Diane L Cox, Julia C DeCesare, Kimberley A Goldsmith, Anthony L Johnson, Paul McCrone, Gabrielle Murphy, Maurice Murphy, Hazel O'Dowd, Laura Potts, Rebacca Walwyn, David Wilks
This article is written in response to the linked editorial by Dr Geraghty about the adaptive Pacing, graded Activity and Cognitive behaviour therapy; a randomised Evaluation (PACE) trial, which we led, implemented and published. The PACE trial compared four treatments for people diagnosed with chronic fatigue syndrome. All participants in the trial received specialist medical care. The trial found that adding cognitive behaviour therapy or graded exercise therapy to specialist medical care was as safe as, and more effective than, adding adaptive pacing therapy or specialist medical care alone...
August 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28805188/managing-faecal-incontinence-in-people-with-advanced-dementia-resident-in-care-homes-finch-study-a-realist-synthesis-of-the-evidence
#3
Claire Goodman, Christine Norton, Marina Buswell, Bridget Russell, Danielle Harari, Rowan Harwood, Brenda Roe, Jo Rycroft-Malone, Vari M Drennan, Mandy Fader, Michelle Maden, Karen Cummings, Frances Bunn
BACKGROUND: Eighty per cent of care home residents in the UK are living with dementia. The prevalence of faecal incontinence (FI) in care homes is estimated to range from 30% to 50%. There is limited evidence of what is effective in the reduction and management of FI in care homes. OBJECTIVE: To provide a theory-driven explanation of the effectiveness of programmes that aim to improve FI in people with advanced dementia in care homes. DESIGN: A realist synthesis...
August 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28803597/somali-latino-and-hmong-parents-perceptions-and-approaches-about-raising-healthy-weight-children-a-community-based-participatory-research-study
#4
Chrisa Arcan, Kathleen A Culhane-Pera, Shannon Pergament, Maira Rosas-Lee, Mai Bao Xiong
OBJECTIVE: Immigrants in the USA are confronted with health disparities, including childhood obesity and obesity-related chronic diseases. We aimed to identify perceptions of childhood body weight, approaches to raising healthy children and desires for supportive programmes of Somali, Latino and Hmong (SLM) parents in the Twin Cities, Minnesota, USA. DESIGN: Using community-based participatory research, ten focus groups (FG) were conducted with sixty-seven parents (n 28 Somali, three FG; n 19 Latino, four FG; n 20 Hmong, three FG) of 3-12-year-old children in their native language...
August 14, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28803534/moving-rehabilitation-research-forward-developing-consensus-statements-for-rehabilitation-and-recovery-research
#5
Julie Bernhardt, Karen Borschmann, Lara Boyd, S Thomas Carmichael, Dale Corbett, Steven C Cramer, Tammy Hoffmann, Gert Kwakkel, Sean Savitz, Gustavo Saposnik, Marion Walker, Nick Ward
Stroke recovery is the next frontier in stroke medicine. While growth in rehabilitation and recovery research is exponential, a number of barriers hamper our ability to rapidly progress the field. Standardized terminology is absent in both animal and human research, methods are poorly described, recovery biomarkers are not well defined, and we lack consistent timeframes or measures to examine outcomes. Agreed methods and conventions for developing, monitoring, evaluating and reporting interventions directed at improving recovery are lacking, and current approaches are often not underpinned by biology...
August 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28801992/associations-between-behaviours-that-challenge-in-adults-with-intellectual-disability-parental-perceptions-and-parental-mental-health
#6
Jane Waite, John Rose, Lucy Wilde, Kate Eden, Chris Stinton, Jo Moss, Chris Oliver
OBJECTIVES: This study examined parental perceptions of behaviours that challenge (CB) in their adult children with intellectual disability (ID), and explored whether perceptions mediated associations between CB and parental psychological distress. DESIGN: A within-group correlational design was employed. METHODS: Sixty-five parents reported on individuals with genetic syndromes and ID who had chronic CB. Parents completed the Illness Perception Questionnaire-Revised (IPQ-R) adapted to measure perceptions of self-injury, aggression or property destruction, alongside assessments of parental locus of control, attributions about behaviour, parental psychological distress, and CB...
August 12, 2017: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28801437/patient-experience-of-nhs-health-checks-a-systematic-review-and-qualitative-synthesis
#7
Juliet A Usher-Smith, Emma Harte, Calum MacLure, Adam Martin, Catherine L Saunders, Catherine Meads, Fiona M Walter, Simon J Griffin, Jonathan Mant
OBJECTIVE: To review the experiences of patients attending NHS Health Checks in England. DESIGN: A systematic review of quantitative and qualitative studies with a thematic synthesis of qualitative studies. DATA SOURCES: An electronic literature search of Medline, Embase, Health Management Information Consortium, Cumulative Index of Nursing and Allied Health Literature, Global Health, PsycInfo, Web of Science, OpenGrey, the Cochrane Library, National Health Service (NHS) Evidence, Google Scholar, Google, Clinical Trials...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28801402/reasons-for-non-adherence-to-cardiometabolic-medications-and-acceptability-of-an-interactive-voice-response-intervention-in-patients-with-hypertension-and-type-2-diabetes-in-primary-care-a-qualitative-study
#8
Aikaterini Kassavou, Stephen Sutton
OBJECTIVES: This study explored the reasons for patients' non-adherence to cardiometabolic medications, and tested the acceptability of the interactive voice response (IVR) as a way to address these reasons, and support patients, between primary care consultations. DESIGN, METHOD, PARTICIPANTS AND SETTING: The study included face-to-face interviews with 19 patients with hypertension and/or type 2 diabetes mellitus, selected from primary care databases, and presumed to be non-adherent...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28801393/protocol-for-the-mwellcare-trial-a-multicentre-cluster-randomised-12-month-controlled-trial-to-compare-the-effectiveness-of-mwellcare-an-mhealth-system-for-an-integrated-management-of-patients-with-hypertension-and-diabetes-versus-enhanced-usual-care-in-india
#9
Dilip Jha, Priti Gupta, Vamadevan S Ajay, Devraj Jindal, Pablo Perel, David Prieto-Merino, Pramod Jacob, Jonathan Nyong, Vidya Venugopal, Kavita Singh, Shifalika Goenka, Ambuj Roy, Nikhil Tandon, Vikram Patel, Dorairaj Prabhakaran
INTRODUCTION: Rising burden of cardiovascular disease (CVD) and diabetes is a major challenge to the health system in India. Innovative approaches such as mobile phone technology (mHealth) for electronic decision support in delivering evidence-based and integrated care for hypertension, diabetes and comorbid depression have potential to transform the primary healthcare system. METHODS AND ANALYSIS: mWellcare trial is a multicentre, cluster randomised controlled trial evaluating the clinical and cost-effectiveness of a mHealth system and nurse managed care for people with hypertension and diabetes in rural India...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28801389/the-role-of-rehabilitation-measures-in-reintegration-of-children-with-brain-tumours-or-leukaemia-and-their-families-after-completion-of-cancer-treatment-a-study-protocol
#10
Mona Leandra Peikert, Laura Inhestern, Corinna Bergelt
INTRODUCTION: For ill children as well as for their parents and siblings, childhood cancer poses a major challenge. Little is known about the reintegration into daily life of childhood cancer survivors and their families. The aim of this prospective observational study is to further the understanding of the role of rehabilitation measures in the reintegration process of childhood leukaemia or brain tumour survivors and their family members after the end of cancer treatment. METHODS AND ANALYSIS: This prospective observational study consists of three study arms: a quantitative study in cooperation with three German paediatric oncological study registries (study arm 1), a quantitative study in cooperation with a rehabilitation clinic that offers a family-oriented paediatric oncological rehabilitation programme (study arm 2) and a qualitative study at 12-month follow-up including families from the study arms 1 and 2 (study arm 3)...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28798403/superparamagnetic-colloids-in-viscous-fluids
#11
A Darras, E Opsomer, N Vandewalle, G Lumay
The influence of a magnetic field on the aggregation process of superparamagnetic colloids has been well known on short time for a few decades. However, the influence of important parameters, such as viscosity of the liquid, has received only little attention. Moreover, the equilibrium state reached after a long time is still challenging on some aspects. Indeed, recent experimental measurements show deviations from pure analytical models in extreme conditions. Furthermore, current simulations would require several years of computing time to reach equilibrium state under those conditions...
August 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28797909/smelling-themselves-dogs-investigate-their-own-odours-longer-when-modified-in-an-olfactory-mirror-test
#12
Alexandra Horowitz
While domestic dogs, Canis familiaris, have been found to be skillful at social cognitive tasks and even some meta-cognitive tasks, they have not passed the test of mirror self-recognition (MSR). Acknowledging the motivational and sensory challenges that might hinder performance, even before the question of self-recognition is broached, this study creates and enacts a novel design extrapolated from the species' natural behaviour. Given dogs' use of olfactory signals in communication, this experiment presents dogs with various canisters for approach and investigation...
August 7, 2017: Behavioural Processes
https://www.readbyqxmd.com/read/28797745/measuring-fracture-toughness-in-biological-materials
#13
David Taylor
Many biological materials fail by cracking. Examples are bone fractures, contact damage in eggs, splits in bamboo culm and defects in cartilage. The mechanical property that best describes failure by cracking is fracture toughness, which quantifies the ease with which cracks propagate and defines a material's tolerance for pre-existing cracks and other stress concentrating features. The measurement of fracture toughness presents some challenges, especially for biological materials. To obtain valid results requires care and, in many cases, considerable ingenuity to design an appropriate specimen and test protocol...
July 5, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28797147/understanding-the-spatial-distribution-of-factors-controlling-topsoil-organic-carbon-content-in-european-soils
#14
M Rial, A Martínez Cortizas, L Rodríguez-Lado
Soil Organic Carbon (SOC) constitutes the largest terrestrial carbon pool. The understanding of its dynamics and the environmental factors that influence its behaviour as sink or source of atmospheric CO2 is crucial to quantify the carbon budget at the global scale. At the European scale, most of the existing studies to account for SOC stocks are centred in the fitting of predictive model to ascertain the distribution of SOC. However, the development of methodologies for monitoring and identifying the environmental factors that control SOC storage in Europe remains a key research challenge...
August 6, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28797081/early-life-predictors-of-adolescent-suicidal-thoughts-and-adverse-outcomes-in-two-population-based-cohort-studies
#15
Jennifer Dykxhoorn, Simon Hatcher, Marie-Hélène Roy-Gagnon, Ian Colman
BACKGROUND: Understanding suicidality has proven challenging given the complex aetiology in early childhood. Being able to accurately predict groups at increased risk of developing suicidal thoughts may aid in the development of targeted prevention programs that mitigate increased vulnerability. Further, the predictors of suicidal thoughts may be shared with other outcomes in adolescence. Previous research has linked many factors to suicidality, so the objective of this study was to consider how these factors may act together to increase risk of suicidal thoughts and other non-mental health outcomes...
2017: PloS One
https://www.readbyqxmd.com/read/28796476/environmental-friendly-and-breathable-fluorinated-polyurethane-fibrous-membranes-exhibiting-robust-waterproof-performance
#16
Jing Zhao, Yang Li, Junlu Sheng, Xianfeng Wang, Lifang Liu, Jianyong Yu, Bin Ding
Waterproof and breathable membranes which provide high level of protection and comfort are promising core materials to meet the pressing demand for future upscale protective clothing. However, creating such materials characterized with environmental protection, high performance and ease of fabrication has proven to be a great challenge. Herein, we report a novel strategy to synthesize fluorinated polyurethane (C6FPU) containing short perfluorohexyl (-C6F13) chains, and introduced it as hydrophobic agent into polyurethane (PU) solution for one-step electrospinning...
August 10, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28795474/endocrine-disruption-in-aquatic-systems-up-scaling-research-to-address-ecological-consequences
#17
Fredric M Windsor, Steve J Ormerod, Charles R Tyler
Endocrine-disrupting chemicals (EDCs) can alter biological function in organisms at environmentally relevant concentrations and are a significant threat to aquatic biodiversity, but there is little understanding of exposure consequences for populations, communities and ecosystems. The pervasive nature of EDCs within aquatic environments and their multiple sub-lethal effects make assessments of their impact especially important but also highly challenging. Herein, we review the data on EDC effects in aquatic systems focusing on studies assessing populations and ecosystems, and including how biotic and abiotic processes may affect, and be affected by, responses to EDCs...
August 9, 2017: Biological Reviews of the Cambridge Philosophical Society
https://www.readbyqxmd.com/read/28795224/extrusion-of-contracaecum-osculatum-nematode-larvae-from-the-liver-of-cod-gadus-morhua
#18
S Zuo, L Barlaup, A Mohammadkarami, A Al-Jubury, D Chen, P W Kania, K Buchmann
Baltic cod livers have during recent years been found increasingly and heavily infected with third-stage larvae of Contracaecum osculatum. The infections are associated with an increasing population of grey seals which are final hosts for the parasite. Heavy worm burdens challenge utilization and safety of the fish liver products, and technological solutions for removal of worms are highly needed. We investigated the attachment of the worm larvae in liver tissue by use of histochemical techniques and found that the cod host encapsulates the worm larvae in layers of host cells (macrophages, fibroblasts) supported by enclosures of collagen and calcium...
August 9, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28794579/temporal-and-geographic-patterns-of-kinship-structure-in-common-dolphins-delphinus-delphis-suggest-site-fidelity-and-female-biased-long-distance-dispersal
#19
Laura Ball, Kypher Shreves, Małgorzata Pilot, André E Moura
ABSTRACT: Social structure plays a crucial role in determining a species' dispersal patterns and genetic structure. Cetaceans show a diversity of social and mating systems, but their effects on dispersal and genetic structure are not well known, in part because of technical difficulties in obtaining robust observational data. Here, we combine genetic profiling and GIS analysis to identify patterns of kin distribution over time and space, to infer mating structure and dispersal patterns in short-beaked common dolphins (Delphinus delphis)...
2017: Behavioral Ecology and Sociobiology
https://www.readbyqxmd.com/read/28794216/higher-songs-of-city-birds-may-not-be-an-individual-response-to-noise
#20
Sue Anne Zollinger, Peter J B Slater, Erwin Nemeth, Henrik Brumm
It has been observed in many songbird species that populations in noisy urban areas sing with a higher minimum frequency than do matched populations in quieter, less developed areas. However, why and how this divergence occurs is not yet understood. We experimentally tested whether chronic noise exposure during vocal learning results in songs with higher minimum frequencies in great tits (Parus major), the first species for which a correlation between anthropogenic noise and song frequency was observed. We also tested vocal plasticity of adult great tits in response to changing background noise levels by measuring song frequency and amplitude as we changed noise conditions...
August 16, 2017: Proceedings. Biological Sciences
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