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https://www.readbyqxmd.com/read/28817817/assessment-of-direct-to-consumer-genetic-testing-policy-in-korea-based-on-consumer-preference
#1
Gicheol Jeong
AIMS: In June 2016, Korea permitted direct-to-consumer genetic testing (DTC-GT) on 42 genes. However, both the market and industry have not yet been fully activated. Considering the aforementioned context, this study provides important insights. METHODS: The Korean DTC-GT policy assessment is based on consumer preference analysis using a discrete choice experiment. In August 2016, a web-based survey was conducted to collect data from 1,200 respondents. RESULTS: The estimation results show that consumers prefer a DTC-GT product that is cheap, tests various items or genes, offers accurate test results, and guarantees the confidentiality of all information...
August 18, 2017: Public Health Genomics
https://www.readbyqxmd.com/read/28815704/the-vibrant-challenges-of-clinically-effective-psychoanalytic-mindedness
#2
Michael J Diamond
In addressing the central challenges of developing and maintaining the analyst's psychoanalytic mindedness, this paper focuses on two particularly challenging core components of clinical effectiveness not so easily developed despite the rigors of the tripartite training model. The first is the analyst's receptivity to unconscious communication, which entails the analyst's curiosity, acceptance of human nature, doubt, restraint, narcissistic balance, and integrity. A brief clinical vignette illustrates this...
July 2017: Psychoanalytic Quarterly
https://www.readbyqxmd.com/read/28815518/organelle-communication-at-membrane-contact-sites-mcs-from-curiosity-to-center-stage-in-cell-biology-and-biomedical-research
#3
Thomas Simmen, Mitsuo Tagaya
Cell biology has long recognized that organelles can communicate with each other. Initially, such communication was thought to occur primarily via vesicular trafficking between biochemically distinct organelles. However, studies starting in the 1970s on lipid metabolism have unearthed another way how organelles can communicate and have spawned the field of membrane contact sites (MCS). While, initially, MCS had been recognized as fluid entities that mediate lipid and ion transport in an ad hoc manner, more recently MCS have been found to depend on protein-protein interactions that control themselves a variety of MCS functions...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28808784/the-history-of-optic-chiasm-from-antiquity-to-the-twentieth-century
#4
REVIEW
Claudia Florida Costea, Şerban Turliuc, Cătălin Buzdugă, Andrei Ionuţ Cucu, Gabriela Florenţa Dumitrescu, Anca Sava, Mihaela Dana Turliuc
PURPOSE: The optic chiasm is an essential structure located at the skull base that stirred over time the curiosity of anatomists, who became more and more interested in its structure and function. Through centuries, the optic chiasm was viewed as a vessel crossing, a way of transporting tears secreted by the brain to the eye, integrating images, or responsible for coordinated eye movements. The paper aims to overview the history of understanding the optic chiasm from the beginnings of antiquity to the twentieth century...
August 14, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28796537/heterosexual-women-s-anal-sex-attitudes-and-motivations-a-focus-group-study
#5
Kimberly R McBride
Focus group methods were used to explore heterosexual women's receptive anal sex attitudes and motivations. Behaviors under investigation included penile-anal intercourse (PAI), manual-anal stimulation, oral-anal contact, and the use of sex toys. A total of 33 self-identified heterosexual women ages 18 to 30 recruited from two metropolitan areas in the Midwestern United States participated in one of six focus groups. The findings suggest that women viewed heterosexual anal sex as an emerging norm. Attitudes and motivations were complex and varied by behavior...
August 10, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/28795856/strengths-based-nursing-a-process-for-implementing-a-philosophy-into-practice
#6
Laurie N Gottlieb, Bruce Gottlieb
Strengths-Based Nursing (SBN) is both a philosophy and value-driven approach that can guide clinicians, educators, manager/leaders, and researchers. SBN is rooted in principles of person/family centered care, empowerment, relational care, and innate health and healing. SBN is family nursing yet not all family nursing models are strengths-based. The challenge is how to translate a philosophy to change practice. In this article, we describe a process of implementation that has organically evolved of a multi-layered and multi-pronged approach that involves patients and families, clinicians, educators, leaders, managers, and researchers as well as key stakeholders including union leaders, opinion leaders, and policy makers from both nursing and other disciplines...
July 1, 2017: Journal of Family Nursing
https://www.readbyqxmd.com/read/28781992/perceived-flavored-smokeless-tobacco-ease-of-use-and-youth-susceptibility
#7
Benjamin W Chaffee, Janelle Urata, Elizabeth T Couch, Stuart A Gansky
OBJECTIVES: Beliefs that flavored smokeless tobacco (ST) is more pleasant, less potent, or otherwise easier to use could contribute to youth initiation. We evaluated associations between perceived ease-of-use of flavored ST (moist snuff and chewing tobacco) and ST initiation susceptibility in a representative sample of US youth. METHODS: Among 7,718 tobacco never-users in the Population Assessment of Tobacco and Health study (age: 12-17; collected: 2013-2014), we compared 4 ST susceptibility items (curiosity, expectation, willingness to try, and a composite) according to whether participants reported flavored ST to be "easier to use" than unflavored ST...
July 2017: Tobacco Regulatory Science
https://www.readbyqxmd.com/read/28777724/active-inference-curiosity-and-insight
#8
Karl J Friston, Marco Lin, Christopher D Frith, Giovanni Pezzulo, J Allan Hobson, Sasha Ondobaka
This article offers a formal account of curiosity and insight in terms of active (Bayesian) inference. It deals with the dual problem of inferring states of the world and learning its statistical structure. In contrast to current trends in machine learning (e.g., deep learning), we focus on how people attain insight and understanding using just a handful of observations, which are solicited through curious behavior. We use simulations of abstract rule learning and approximate Bayesian inference to show that minimizing (expected) variational free energy leads to active sampling of novel contingencies...
August 4, 2017: Neural Computation
https://www.readbyqxmd.com/read/28776383/hepatocellular-carcinoma-in-patients-without-advanced-fibrosis-after-eradication-of-hcv-with-antiviral-treatment
#9
Yolanda Sánchez-Torrijos, Jara Eloísa Ternero Vega, Carmen Cepeda Franco
From the last few years, hepatitis C virus and the new direct antiviral treatments are being more and more important. In consequence, case studies like the one we present, the appearance of hepatocelullar carcinoma after its eradication with fibrosis grade 2, are getting special interest. In 2007, our patient was treated with pegylated interferon α-2a and ribavirin, having a sustained virological response after it. In this way, liver fibrosis grade 2 was confirmed by a biopsy. Finally, after corroborating a good liver functioning, the patient was discharged (as, according to the guidebooks, an ultrasound scan of screeing every 6 months was not required)...
August 4, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28776003/the-tip-of-the-tongue-state-and-curiosity
#10
Janet Metcalfe, Bennett L Schwartz, Paul A Bloom
Theories of study time allocation and of curiosity suggest that people are most engaged with and want to devote their time to materials that are not completely mastered but also are not so difficult that they might be impossible. Their curiosity is thought to be triggered by items that are almost known, or are in what is sometimes called the region of proximal learning. Answers that are on the tip-of-the-tongue (TOT)-not immediately recallable but nevertheless evoking a feeling of imminent recall-seem, intuitively, to be materials that have this characteristic of being almost, but not quite, fully known...
2017: Cognitive Research: Principles and Implications
https://www.readbyqxmd.com/read/28771029/methane-seepage-on-mars-where-to-look-and-why
#11
Dorothy Z Oehler, Giuseppe Etiope
Methane on Mars is a topic of special interest because of its potential association with microbial life. The variable detections of methane by the Curiosity rover, orbiters, and terrestrial telescopes, coupled with methane's short lifetime in the martian atmosphere, may imply an active gas source in the planet's subsurface, with migration and surface emission processes similar to those known on Earth as "gas seepage." Here, we review the variety of subsurface processes that could result in methane seepage on Mars...
August 3, 2017: Astrobiology
https://www.readbyqxmd.com/read/28749074/crediting-curiosity-and-creativity-in-young-scientists-beyond-the-standard-publication-record-%C3%A2
#12
EDITORIAL
Andrew Moore
No abstract text is available yet for this article.
August 2017: BioEssays: News and Reviews in Molecular, Cellular and Developmental Biology
https://www.readbyqxmd.com/read/28746802/leading-by-gaslight-nursing-s-academic-leadership-struggles
#13
EDITORIAL
David R Thompson, Alexander M Clark
What characterizes strong nursing leadership in academia? Not what you might think. Popular mythology may suggest strength and certainty: people who transcend, get their way, and "call" the important decisions (Brown 2014). Yet, historian Archie Brown (2014) analyzing hundreds of leaders over hundreds of years suggests otherwise, with: integrity, relationship building, collegiality, curiosity, willingness to seek disparate views, empathy and energy being far more important (Brown 2014). Stereotypical strength, it transpires, is steadfast weakness...
July 26, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28746497/revealing-an-hiv-diagnosis-for-children-and-adolescents-subsidy-for-the-practice-of-care
#14
Bruna Pase Zanon, Cristiane Cardoso de Paula, Stela Maris de Mello Padoin
Objective: To collectively build a guide for following-up on HIV diagnosis disclosure to children and adolescents in a specialized service. Method: Convergent-care research approach with observation triangulation, interview and groups, conducted from May to June 2015 with seven health professionals in a pediatric outpatient clinic for infectious diseases. Thematic content analysis was developed. Results: The discussion of understanding the disclosure, its triggers, actors involved, used strategies, and limits and possibilities listed by the professionals subsidized the construction of a guide to be applied in the stages: analyzing children's questions and curiosities; evaluating their cognitive ability; discussing the reasons to reveal; listing the professionals involved on follow-up process; including family; developing strategies for disclosure...
July 20, 2017: Revista Gaúcha de Enfermagem
https://www.readbyqxmd.com/read/28744245/distinguishing-relational-aspects-of-character-strengths-with-subjective-and-psychological-well-being
#15
Melanie Hausler, Cornelia Strecker, Alexandra Huber, Mirjam Brenner, Thomas Höge, Stefan Höfer
Research has shown that character strengths are positively linked with well-being in general. However, there has not been a fine-grained analysis up to date. This study examines the individual relational aspects between the 24 character strengths, subjective well-being (SWB), and different aspects of psychological well-being (PWB) at two times of measurement (N = 117). Results showed that overall the "good character" was significantly stronger related with PWB than with SWB. The character strength "hope" was at least moderately correlated with the PWB aspects meaning, optimism and autonomy, and "zest" with the PWB aspects relationships and engagement...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28743589/density-functionalized-ru-ii-no-salen-cl-complex-computational-photodynamics-and-in-vitro-anticancer-facets
#16
Jan Mohammad Mir, N Jain, P S Jaget, R C Maurya
Photodynamic therapy (PDT) is a treatment that uses photosensitizing agents to kill cancer cells. Scientific community has been eager for decades in enduring curiosity to design an efficient PDT drug. Under such purview, the current report deals with the computational photodynamic behavior of ruthenium(II) nitrosyl complex containing N, N'-salicyldehyde-ethylenediimine (SalenH2), the synthesis and X-ray crystallography of which is already known [Ref. 36]. Gaussian 09W software package was employed to carry out the density functional (DFT) studies...
July 22, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28725218/all-new-faces-of-diatoms-potential-source-of-nanomaterials-and-beyond
#17
REVIEW
Meerambika Mishra, Ananta P Arukha, Tufail Bashir, Dhananjay Yadav, G B K S Prasad
Nature's silicon marvel, the diatoms have lately astounded the scientific community with its intricate designs and lasting durability. Diatoms are a major group of phytoplanktons involved in the biogeochemical cycling of silica and are virtually inherent in every environment ranging from water to ice to soil. The usage of diatoms has proved prudently cost effective and its handling neither requires costly materials nor sophisticated instruments. Diatoms can easily be acquired from the environment, their culture requires ambient condition and does not involve any costly media or expensive instruments, besides, they can be transported in small quantities and proliferated to a desirable confluence from that scratch, thus are excellent cost effective industrial raw material...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28720629/a-group-visit-initiative-improves-advance-care-planning-documentation-among-older-adults-in-primary-care
#18
Hillary D Lum, Rebecca L Sudore, Daniel D Matlock, Elizabeth Juarez-Colunga, Jacqueline Jones, Molly Nowels, Robert S Schwartz, Jean S Kutner, Cari R Levy
INTRODUCTION: Group visits for advance care planning (ACP) may help patients document preferences for decision makers and future care. We assessed the impact of a primary care-based ACP group visit (ACP-GV) intervention on older adults' ACP documentation and why patients participated. METHODS: Older adults (>65 years) in primary care participated in a 2-session ACP-GV intervention that promotes group dynamics, peer-based learning, and goal setting. Charts were reviewed at baseline, 3 months, and 12 months for documentation of decision makers and ACP forms...
July 2017: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28719176/investigation-on-the-electrocatalytic-determination-and-photocatalytic-degradation-of-neurotoxicity-drug-clioquinol-by-sn-moo4-2-nanoplates
#19
Raj Karthik, Jeyaraj Vinoth Kumar, Shen-Ming Chen, Kumar Seerangan, Chelladurai Karuppiah, Tse-Wei Chen, Velluchamy Muthuraj
Transition-metal molybdates have concerned enormous curiosity as supercapacitors, photocatalysts, and electrocatalysts. These materials are the best alternatives to noble-metal-based catalysts, which are generally show a limited photocatalytic and electrocatalytic activity. In addition, the antiprotozoal drug can usually pollute the environment through improper disposable and incomplete metabolism, and it is very dangerous to humans as well as aquatic animals. Therefore, here, we have studied the electrochemical determination and photodegradation of neurotoxicity clioquinol (CQL) by nanoplate-like tin molybdate (Sn(MoO4)2, denoted as SnM), which is used as both an electro- and a photocatalyst...
August 9, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28700584/the-selfish-germ
#20
Andrew F Read
Curiosity about the sex life of a wasp led to a new way of thinking and a powerful demonstration that evolutionary science could be predictive. That same approach could help find ways to slow or prevent treatment failures in cancer and infectious diseases.
July 2017: PLoS Biology
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