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https://www.readbyqxmd.com/read/28101267/bioart-and-bildung-wetware-art-agency-animation-an-exhibition-as-case-study
#1
Charissa N Terranova
Recent events in the field of biology have further unfixed the definition of life. The negotiability of "life" is at the center of the exhibition "Wetware: Art, Agency, Animation" at the Beall Center for Art + Technology at the University of California, Irvine. The exhibition includes art by nine international artists working in the avant-garde area of contemporary art called "bioart." This article is devoted to the unique educational space opened through the practice of bioart, focusing on how the exhibition brings the scientific question "What is life?" to a public audience...
December 2016: Journal of Microbiology & Biology Education: JMBE
https://www.readbyqxmd.com/read/28098998/chemical-and-antioxidant-properties-of-betalains
#2
Imen Belhadj Slimen, Taha Najar, Manef Abderrabba
Betalains are vacuolar pigments composed of a nitrogenous core structure, betalamic acid. Betalamic acid condenses with imino compounds (cyclo-DOPA/its glucosyl derivates) or amino acids/derivates to form violet betacyanins and yellow betaxanthins. These pigments have gained the curiosity of scientific researchers in recent decades. Their importance was increased not only by market orientation toward natural colorants and antioxidants but also by their safety and health promoting properties. To date, about 78 betalains have been identified from plants of about 17 families...
January 18, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28098627/global-collaboration-in-acute-care-clinical-research-opportunities-challenges-and-needs
#3
John C Marshall
The most impactful research in critical care comes from trials groups led by clinician-investigators who study questions arising through the day-to-day care of critically ill patients. The success of this model reflects both "necessity"-the paucity of new therapies introduced through industry-led research-and "clinical reality"-nuanced modulation of standard practice can have substantial impact on clinically important outcomes. Success in a few countries has fueled efforts to build similar models around the world and to collaborate on an unprecedented scale in large international trials...
February 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28098483/academic-performance-on-first-year-medical-school-exams-how-well-does-it-predict-later-performance-on-knowledge-based-and-clinical-assessments
#4
Edward Krupat, Stephen R Pelletier, Jules L Dienstag
Number of appearances in the bottom quartile of 1st-year medical school exams were used to represent the extent to which students were having academic difficulties. Medical educators have long expressed a desire to have indicators of medical student performance that have strong predictive validity. Predictors traditionally used fell into 4 general categories: demographic (e.g., gender), other background factors (e.g., college major), performance/aptitude (e.g., medical college admission test scores), and noncognitive factors (e...
January 18, 2017: Teaching and Learning in Medicine
https://www.readbyqxmd.com/read/28092792/curiosity-improves-coping-efficacy-and-reduces-suicidal-ideation-severity-among-military-veterans-at-risk-for-suicide
#5
Lauren M Denneson, Derek J Smolenski, Nigel E Bush, Steven K Dobscha
Curiosity, the tendency to engage in novel and challenging opportunities, may be an important source of resilience for those at risk for suicide. We hypothesized that curiosity would have a buffering effect against risk conferred by multiple sources of distress, whereby curiosity would be associated with reduced suicidal ideation and increased coping efficacy. As part of a larger intervention trial designed to improve coping skills and reduce suicidal ideation, 117 military veterans with suicidal ideation completed measures of curiosity and distress (perceived stress, depression, anxiety, and sleep disturbances) at baseline, and completed measures of suicidal ideation and coping efficacy (to stop negative thoughts, to enlist support from friends and family) at baseline and 3-, 6-, and 12-week follow up...
January 9, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28087134/factors-influencing-and-modifying-the-decision-to-pursue-genetic-testing-for-skin-cancer-risk
#6
Alexander L Fogel, Prajakta D Jaju, Shufeng Li, Bonnie Halpern-Felsher, Jean Y Tang, Kavita Y Sarin
BACKGROUND: Across cancers, the decision to pursue genetic testing is influenced more by subjective than objective factors. However, skin cancer, which is more prevalent, visual, and multifactorial than many other malignancies, may offer different motivations for pursuing such testing. OBJECTIVES: The primary objective was to determine factors influencing the decision to receive genetic testing for skin cancer risk. A secondary objective was to assess the impact of priming with health questions on the decision to receive testing...
January 10, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28086875/learning-global-health-a-pilot-study-of-an-online-collaborative-intercultural-peer-group-activity-involving-medical-students-in-australia-and-indonesia
#7
Mark Ambrose, Linda Murray, Nicholas E Handoyo, Deif Tunggal, Nick Cooling
BACKGROUND: There is limited research to inform effective pedagogies for teaching global health to undergraduate medical students. Theoretically, using a combination of teaching pedagogies typically used in 'international classrooms' may prove to be an effective way of learning global health. This pilot study aimed to explore the experiences of medical students in Australia and Indonesia who participated in a reciprocal intercultural participatory peer e-learning activity (RIPPLE) in global health...
January 13, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28079298/from-phosphoproteins-to-phosphoproteomes-a-historical-account
#8
REVIEW
Andrea Venerando, Luca Cesaro, Lorenzo A Pinna
The first phosphoprotein (casein) was discovered in 1883, yet the enzyme responsible for its phosphorylation was identified only 130 years later, in 2012. During the very long time elapsed between these two events, with special reference to the last decades of the 1900s, it became evident that, far from being an oddity, phosphorylation affects the majority of eukaryotic proteins during their lifespan, and that this reaction is catalysed by the members of a large family of protein kinases, susceptible to a variety of stimuli controlling nearly every aspects of life and death...
January 12, 2017: FEBS Journal
https://www.readbyqxmd.com/read/28079064/lasing-action-from-photonic-bound-states-in-continuum
#9
Ashok Kodigala, Thomas Lepetit, Qing Gu, Babak Bahari, Yeshaiahu Fainman, Boubacar Kanté
In 1929, only three years after the advent of quantum mechanics, von Neumann and Wigner showed that Schrödinger's equation can have bound states above the continuum threshold. These peculiar states, called bound states in the continuum (BICs), manifest themselves as resonances that do not decay. For several decades afterwards the idea lay dormant, regarded primarily as a mathematical curiosity. In 1977, Herrick and Stillinger revived interest in BICs when they suggested that BICs could be observed in semiconductor superlattices...
January 11, 2017: Nature
https://www.readbyqxmd.com/read/28069437/indispensable-role-of-the-voltage-gated-calcium-channels-in-the-procognitive-effects-of-angiotensin-iv
#10
Jan Józef Braszko
BACKGROUND: Voltage-gated calcium channels (VGCCs) play a major role in brain functioning, including that of cognition-related structures such as cerebral cortex and hippocampus. Cellular mechanisms underlying learning and memory enhancing effect of the neuropeptide angiotensin IV (Ang IV) have been linked to VGCCs but only in respect of its long-term potentiation (LTP)-inducing effect. OBJECTIVE: To assess behaviorally effects of L- and T-type VGCCs blocking drugs in low, behaviorally inactive, doses on Ang IV facilitation of recall of aversively (foot-shock) and appetitively (curiosity for novelty) motivated behaviors...
January 6, 2017: Brain Research Bulletin
https://www.readbyqxmd.com/read/28067260/orientation-toward-humans-predicts-cognitive-performance-in-orang-utans
#11
Laura A Damerius, Sofia I F Forss, Zaida K Kosonen, Erik P Willems, Judith M Burkart, Josep Call, Birute M F Galdikas, Katja Liebal, Daniel B M Haun, Carel P van Schaik
Non-human animals sometimes show marked intraspecific variation in their cognitive abilities that may reflect variation in external inputs and experience during the developmental period. We examined variation in exploration and cognitive performance on a problem-solving task in a large sample of captive orang-utans (Pongo abelii &P. pygmaeus, N = 103) that had experienced different rearing and housing conditions during ontogeny, including human exposure. In addition to measuring exploration and cognitive performance, we also conducted a set of assays of the subjects' psychological orientation, including reactions towards an unfamiliar human, summarized in the human orientation index (HOI), and towards novel food and objects...
January 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28062060/providing-appropriate-end-of-life-care-to-religious-and-ethnic-minorities
#12
REVIEW
Daniel K Partain, Cory Ingram, Jacob J Strand
There is overwhelming evidence that racial and ethnic minorities face multiple health care disparities. Recognizing and addressing cultural and religious/spiritual (RS) values is a critical aspect of providing goal-concordant care for patients facing a serious illness, especially at the end of life. Failure to address a patient's cultural and RS needs can lead to diminished quality of care and worse health outcomes. Given the multitude of cultural and RS values, we believe that a framework of cultural and RS curiosity along with a willingness to engage patients in discussions about these elements of their care within an interdisciplinary team should be the goal of all providers who are discussing goals, preferences, and values with patients facing advanced terminal illness...
January 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28059790/combined-creutzfeldt-jakob-jacob-alzheimer-s-disease-cases-are-important-in-search-for-microbes-in-alzheimer-s-disease
#13
Frank O Bastian
The question whether Alzheimer's disease is infectious as brought up in the recent editorial published in the Journal of Alzheimer's Disease is complicated by the controversy whether the causal agent is a microbe or a misfolded host protein (amyloid). The replicating amyloid (prion) theory, based upon data from studies of Creutzfeldt-Jakob disease (CJD) and other transmissible spongiform encephalopathies (TSEs), has been challenged since the prion can be separated from TSE infectivity, and spiroplasma, a wall-less bacterium, has been shown to be involved in the pathogenesis of CJD...
December 3, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28059655/norman-m-dott-master-of-hypothalamic-craniopharyngioma-surgery-the-decisive-mentoring-of-harvey-cushing-and-percival-bailey-at-peter-bent-brigham-hospital
#14
Ruth Prieto, José M Pascual
Norman McOmish Dott (1897-1973) developed surgical neurology in Edinburgh, Scotland, and was a scholar of worldwide renown. One of Dott's most notable contributions to neurosurgery was his understanding of hypothalamic physiology, mostly acquired through the comprehensive study of patients with lesions involving this region of the diencephalon, particularly craniopharyngiomas (CPs). Recognition of symptoms caused by hypothalamic disturbances allowed him to predict the accurate anatomical relationships between CPs and the hypothalamus, despite the rudimentary radiological methods available during the 1930s...
January 6, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28051054/appendicular-bilharzioma-an-unusual-cause-of-acute-intestinal-obstruction-in-childhood-a-case-report-at-charles-de-gaulle-paediatric-teaching-hospital-of-ouagadougou
#15
Albert Wandaogo, Isso Ouédraogo, Toussaint Wendlamita Tapsoba, Emile Bandré, Francis Somkieta Ouédraogo, Bernadette Béré, Balima Elie
The authors report the case of a 12-year-old boy admitted to the surgical emergency department of Charles de Gaulle Paediatric Teaching Hospital of Ouagadougou for acute abdominal pain. A strangulation of the terminal ileum by a tumour-like appendix wound around the bowel loop was seen during operation. The histological examination of the removed appendix disclosed eggs of Schistosoma haematobium and concluded to bilharzian appendicitis. A course of praziquantel treatment was instituted, and the patient underwent an event-free recovery...
October 2016: African Journal of Paediatric Surgery: AJPS
https://www.readbyqxmd.com/read/28042200/adolescents-conceived-through-donor-insemination-in-mother-headed-families-a%C3%A2-qualitative-study-of-motivations-and-experiences-of-contacting-and-meeting-same-donor-offspring
#16
Sherina Persaud, Tabitha Freeman, Vasanti Jadva, Jenna Slutsky, Wendy Kramer, Miriam Steele, Howard Steele, Susan Golombok
This study interviewed adolescents conceived using sperm donation to examine their experiences of contacting and meeting 'same-donor offspring' (i.e. donor-conceived offspring raised in different families who share the same donor), their motivations for this contact, and how they make meaning of these relationships. This in-depth qualitative study involved semi-structured interviews with 23 young people aged 12-19 years (mean = 14 years). Interviewees were motivated by curiosity about their biological relations and by wanting to extend their family...
January 2017: Children & Society
https://www.readbyqxmd.com/read/28024434/twelve-tips-on-writing-a-discussion-case-that-facilitates-teaching-and-engages-learners
#17
David A Cohen, Lori R Newman, Laurie N Fishman
The authors share twelve practical tips on writing a case that engages learners in active learning and discussion. They first advise that, during the initial preparation of the case, authors should (1) identify the case goals and objectives, and (2) identify the level of the learners. When writing the case, authors should (3) use active and colorful language; (4) use patients' own descriptions rather than medical language; (5) allow the learners to interpret data themselves; (6) allow for natural discovery rather than presenting information chronologically; and (7) be realistic about interruptions in patient care...
December 26, 2016: Medical Teacher
https://www.readbyqxmd.com/read/28018613/synthesis-and-characterization-of-azo-guanidine-based-alcoholic-media-naked-eye-dna-sensor
#18
Ataf Ali Altaf, Uzma Hashmat, Muhammad Yousaf, Bhajan Lal, Shafiq Ullah, Alvin A Holder, Amin Badshah
DNA sensing always has an open meadow of curiosity for biotechnologists and other researchers. Recently, in this field, we have introduced an emerging class of molecules containing azo and guanidine functionalities. In this study, we have synthesized three new compounds (UA1, UA6 and UA7) for potential application in DNA sensing in alcoholic medium. The synthesized materials were characterized by elemental analysis, FTIR, UV-visible, (1)H NMR and (13)C NMR spectroscopies. Their DNA sensing potential were investigated by UV-visible spectroscopy...
November 2016: Royal Society Open Science
https://www.readbyqxmd.com/read/28007352/esophageal-cancer-in-high-risk-areas-of-china-research-progress-and-challenges
#19
REVIEW
Yingsong Lin, Yukari Totsuka, Baoen Shan, Chaochen Wang, Wenqiang Wei, Youlin Qiao, Shogo Kikuchi, Manami Inoue, Hideo Tanaka, Yutong He
PURPOSE: The extremely high incidence of esophageal cancer in certain rural areas of China has prompted significant intellectual curiosity and research efforts both in China and abroad. METHODS: We summarize the research progress over the past several decades in high-risk areas (Linxian, Cixian, Shexian, and Yanting) based on literature research and our field trip (2012-2013). RESULTS: Considerable progress in clarifying the environmental risk factors and pathogenesis of esophageal cancer in high-risk areas has been achieved over the past several decades...
November 25, 2016: Annals of Epidemiology
https://www.readbyqxmd.com/read/28006824/correction-curiosity-search-producing-generalists-by-encouraging-individuals-to-continually-explore-and-acquire-skills-throughout-their-lifetime
#20
Christopher Stanton, Jeff Clune
[This corrects the article DOI: 10.1371/journal.pone.0162235.].
2016: PloS One
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