keyword
https://read.qxmd.com/read/38537027/home-vs-gym-based-exercise-delivery-modes-of-two-multicomponent-intensity-training-regimes-on-cardiorespiratory-fitness-and-arterial-stiffness-in-adults-with-intellectual-and-developmental-disability-during-the-covid-19-pandemic-a-randomized-controlled-trial
#1
JOURNAL ARTICLE
Xavier Melo, Bruno Simão, Catarina Catela, Isabel Oliveira, Sara Planche, Ana Louseiro, João Luís Marôco, Guillermo R Oviedo, Bo Fernhall, Helena Santa-Clara
Background: We compared the effects of home- vs gym-based delivery modes of two 8-week supervised multicomponent intensity training regimes on cardiorespiratory fitness and arterial stiffness in 17 adults with intellectual and developmental disability during the COVID-19 pandemic. Methods : Participants were assigned to sprint interval training or continuous aerobic training, both incorporating resistance training. The intervention started with 8-weeks of online training (M1-M2), 1-month of detraining, plus 8-weeks of gym-based training (M3-M4)...
March 27, 2024: Journal of Intellectual Disabilities: JOID
https://read.qxmd.com/read/38537013/assessing-peri-implant-bone-microarchitecture-conventional-vs-osseodensification-drilling-ex-vivo-analysis
#2
JOURNAL ARTICLE
Breno Fortes Bittar, Bruno Salles Sotto-Maior, Karina Lopes Devito, Gustavo Davi Rabelo, Alessandra Silveira Machado, Ricardo Tadeu Lopes, Neuza Maria Souza Picorelli Assis
The aim was to evaluate primary implant stability and bone microarchitecture in two drilling situations, by comparing the conventional technique (CT) and osseodensification (OD) (Versah Burs - Jackson - Mississippi - USA). The implant insertion torque (IT), implant stability quotient (ISQ), and the peri-implant trabecular microstructure were assessed on bone fragments obtained from pig's tibia (n=12), divided between CT (n=6) and OD (n=6). After the drilling procedure, the implants were installed (3.5x8.5 mm, Epikut - SIN - São Paulo - Brazil)...
2024: Brazilian Dental Journal
https://read.qxmd.com/read/38536987/arteriovenous-malformation
#3
JOURNAL ARTICLE
Edson Marchiori, Bruno Hochhegger, Gláucia Zanetti
No abstract text is available yet for this article.
March 22, 2024: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://read.qxmd.com/read/38536982/lung-cancer-screening-in-brazil-recommendations-from-the-brazilian-society-of-thoracic-surgery-brazilian-thoracic-association-and-brazilian-college-of-radiology-and-diagnostic-imaging
#4
JOURNAL ARTICLE
Luiz Fernando Ferreira Pereira, Ricardo Sales Dos Santos, Daniel Oliveira Bonomi, Juliana Franceschini, Ilka Lopes Santoro, André Miotto, Thiago Lins Fagundes de Sousa, Rodrigo Caruso Chate, Bruno Hochhegger, Artur Gomes Neto, Airton Schneider, César Augusto de Araújo Neto, Dante Luiz Escuissato, Gustavo Faibischew Prado, Luciana Costa-Silva, Mauro Musa Zamboni, Mario Claudio Ghefter, Paulo César Rodrigues Pinto Corrêa, Pedro Paulo Teixeira E Silva Torres, Ricardo Kalaf Mussi, Valdair Francisco Muglia, Irma de Godoy, Wanderley Marques Bernardo
Although lung cancer (LC) is one of the most common and lethal tumors, only 15% of patients are diagnosed at an early stage. Smoking is still responsible for more than 85% of cases. Lung cancer screening (LCS) with low-dose CT (LDCT) reduces LC-related mortality by 20%, and that reduction reaches 38% when LCS by LDCT is combined with smoking cessation. In the last decade, a number of countries have adopted population-based LCS as a public health recommendation. Albeit still incipient, discussion on this topic in Brazil is becoming increasingly broad and necessary...
2024: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://read.qxmd.com/read/38536534/serial-daily-lactate-levels-association-with-30-day-outcome-in-cardiogenic-shock-patients-treated-with-va-ecmo-a-post-hoc-analysis-of-the-hypo-ecmo-study
#5
JOURNAL ARTICLE
Bruno Levy, Nicolas Girerd, Guillaume Baudry, Kevin Duarte, Samuel Cuau, Jan Bakker, Antoine Kimmoun
BACKGROUND: Reliable predictors of outcomes in venoarterial extracorporeal membrane oxygenation (VA-ECMO) therapy are limited. While elevated lactate levels over time have been linked to outcomes in cardiogenic shock (CS), their significance in VA-ECMO-treated patients remains inconclusive. METHODS: We conducted a post hoc analysis of data from the HYPO-ECMO trial, which compared normothermia to moderate hypothermia in CS patients supported by VA-ECMO. We examined daily lactate levels collected over a week to assess their correlation with 30-day mortality...
March 27, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38535984/italian-society-of-interventional-cardiology-gise-and-italian-society-of-arterial-hypertension-siia-position-paper-on-the-role-of-renal-denervation-in-the-management-of-the-difficult-to-treat-hypertension
#6
JOURNAL ARTICLE
Eugenio Stabile, Maria L Muiesan, Flavio L Ribichini, Giuseppe Sangiorgi, Stefano Taddei, Francesco Versaci, Bruno Villari, Alessandra Bacca, Daniela Benedetto, Vincenzo Fioretti, Eugenio Laurenzano, Massimilano Scapaticci, Francesco Saia, Giuseppe Tarantini, Guido Grassi, Giovanni Esposito
Renal denervation (RDN) is a safe and effective strategy for the treatment of difficult to treat hypertension. The blood pressure (BP)-lowering efficacy of RDN is comparable to those of many single antihypertensive medications and it allows to consider the RDN as a valuable option for the treatment of difficult to treat hypertension together with lifestyle modifications and medical therapy. A multidisciplinary team is of pivotal importance from the selection of the patient candidate for the procedure to the post-procedural management...
March 27, 2024: Minerva cardiology and angiology
https://read.qxmd.com/read/38535945/long-term-environmental-methylmercury-exposure-is-associated-with-peripheral-neuropathy-and-cognitive-impairment-among-an-amazon-indigenous-population
#7
JOURNAL ARTICLE
Bruno H Rebouças, Gabriel T Kubota, Rogério A A Oliveira, Bruna D Pinto, Roberta M Cardoso, Ana C S Vasconcellos, Paulo C Basta
Widespread contamination of the Amazon basin with mercury has been reported to occur since at least the mid-80s due to heavy gold mining activity. Although initial studies have indicated that this may lead to deleterious neurological consequences to the indigenous populations living in the region, further research is needed to better characterize the neurological burden of such long-term exposure. With this aim, a cross-sectional exploratory study has been conducted with the Yanomami indigenous population residing in a northern Amazon region...
March 12, 2024: Toxics
https://read.qxmd.com/read/38535937/trends-in-mercury-contamination-distribution-among-human-and-animal-populations-in-the-amazon-region
#8
REVIEW
Irvin Martoredjo, Lenize Batista Calvão Santos, Jéssica Caroline Evangelista Vilhena, Alex Bruno Lobato Rodrigues, Andréia de Almeida, Carlos José Sousa Passos, Alexandro Cezar Florentino
Mercury contamination in the Amazon arising from both natural sources and intensive mining activities in the region is a significant public health concern. This metal is used to separate Au from sediments. Accordingly, this study aimed to assess the impact of mining on mercury contamination in the animal and human populations of the Amazon. This overall objective was pursued through a systematic review of the existing literature to assess the impact of Hg and identify gaps in geographic coverage arising from this assessment...
March 7, 2024: Toxics
https://read.qxmd.com/read/38535932/herbicide-leaching-in-soil-with-different-properties-perspectives-from-commercial-formulations-and-analytical-standards
#9
JOURNAL ARTICLE
Rita de Cássia Araújo de Medeiros, Tatiane Severo Silva, Taliane Maria da Silva Teófilo, Francisca Daniele da Silva, Matheus de Freitas Souza, Ana Beatriz Rocha de Jesus Passos, Bruno Caio Chaves Fernandes, Hamurábi Anizio Lins, Paulo Sergio Fernandes das Chagas, Carolina Malala Martins Souza, Ioná Santos Araújo Holanda, Daniel Valadão Silva
The leaching of herbicides into the soil is essential to control germinating seeds and parts of vegetative weeds. However, herbicide transportation to deeper soil layers can result in groundwater contamination and, consequently, environmental issues. In this research, our objective was to investigate differences in herbicide leaching between commercial formulations and analytical standards using three different soils. Leaching experiments were carried out for diuron, hexazinone, and sulfometuron-methyl herbicides isolated and in binary and ternary mixtures...
March 2, 2024: Toxics
https://read.qxmd.com/read/38535859/intraoperative-isoflurane-end-tidal-concentration-during-infusion-of-fentanyl-tramadol-or-fentanyl-tramadol-combination-in-cats
#10
JOURNAL ARTICLE
Claudia Interlandi, Fabio Bruno, Marco Tabbì, Francesco Macrì, Simona Di Pietro, Elisabetta Giudice, Patrizia Licata, Daniele Macrì, Viola Zappone, Giovanna Lucrezia Costa
The aim of this study was to evaluate the end-tidal concentration of isoflurane required, clinical parameters, intraoperative antinociceptive effect, and postoperative analgesia in cats undergoing ovariohysterectomy, receiving fentanyl, tramadol, or fentanyl/tramadol. Sixty-six cats in three groups, were premedicated with dexmedetomidine and infused with one of the following treatments: fentanyl, tramadol, or fentanyl/tramadol combination. Anesthesia was induced with alfaxolone and maintained with isoflurane, titrated to keep heart rate, respiratory rate and systolic arterial pressure within target values recorded at endotracheal intubation...
March 11, 2024: Veterinary Sciences
https://read.qxmd.com/read/38535855/the-performance-of-using-the-parasympathetic-tone-activity-pta-index-to-assess-intraoperative-nociception-in-cats
#11
JOURNAL ARTICLE
Leonor Lima, José Diogo Dos-Santos, Lénio Ribeiro, Patrícia Cabral, Bruno Colaço, João Martins
BACKGROUND: The monitoring of nociception/antinociception poses a significant challenge during anesthesia, making the incorporation of new tools like the Parasympathetic Tone Activity (PTA) monitor an added value in feline anesthesia. OBJECTIVES: To compare the effectiveness and speed of PTA monitoring when compared to heart rate (HR) in detecting surgical stimuli (SS) during the intraoperative period in 49 female cats undergoing ovariectomy (OV). METHODS: Instantaneous Parasympathetic Tone Activity (PTAi) values, HR, f R , and non-invasive SAP and MAP were continuously monitored and systematically assessed...
March 6, 2024: Veterinary Sciences
https://read.qxmd.com/read/38535788/assessment-of-the-impact-of-humic-acids-on-intestinal-microbiota-gut-integrity-ileum-morphometry-and-cellular-immunity-of-turkey-poults-fed-an-aflatoxin-b-1-contaminated-diet
#12
JOURNAL ARTICLE
Jesús A Maguey-González, Jing Liu, Guolong Zhang, Juan D Latorre, Juan O Hernández-Ramírez, María de Jesús Nava-Ramírez, Roberto Senas-Cuesta, Sergio Gómez-Rosales, María de Lourdes Ángeles, Andressa Stein, Bruno Solís-Cruz, Daniel Hernández-Patlán, Rubén Merino-Guzmán, Xochitl Hernandez-Velasco, Inkar Castellanos-Huerta, Santiago Uribe-Diaz, Alma Vázquez-Durán, Abraham Méndez-Albores, Victor M Petrone-Garcia, Guillermo Tellez, Billy M Hargis, Guillermo Téllez-Isaías
A recent study published data on the growth performance, relative weights of the organs of the gastrointestinal tract, liver histology, serum biochemistry, and hematological parameters for turkey poults fed an experimental diet contaminated with aflatoxin B1 (AFB1 ) and humic acids (HA) extracted from vermicompost. The negative effects of AFB1 (250 ng AFB1 /g of feed) were significantly reduced by HA supplementation (0.25% w / w ), suggesting that HA might be utilized to ameliorate the negative impact of AFB1 from contaminated diets...
February 29, 2024: Toxins
https://read.qxmd.com/read/38535625/targeted-and-self-adjuvated-nanoglycovaccine-candidate-for-cancer-immunotherapy
#13
JOURNAL ARTICLE
Rui Freitas, Eduardo Ferreira, Andreia Miranda, Dylan Ferreira, Marta Relvas-Santos, Flávia Castro, Beatriz Santos, Martina Gonçalves, Sofia Quintas, Andreia Peixoto, Carlos Palmeira, André M N Silva, Lúcio Lara Santos, Maria José Oliveira, Bruno Sarmento, José Alexandre Ferreira
Advanced-stage solid primary tumors and metastases often express mucin 16 (MUC16), carrying immature glycans such as the Tn antigen, resulting in specific glycoproteoforms not found in healthy human tissues. This presents a valuable approach for designing targeted therapeutics, including cancer glycovaccines, which could potentially promote antigen recognition and foster the immune response to control disease spread and prevent relapse. In this study, we describe an adjuvant-free poly(lactic- co -glycolic acid) (PLGA)-based nanoglycoantigen delivery approach that outperforms conventional methods by eliminating the need for protein carriers while exhibiting targeted and adjuvant properties...
March 27, 2024: ACS Nano
https://read.qxmd.com/read/38535507/proteoform-analysis-of-the-human-olfactory-system-a-window-into-neurodegenerative-diseases
#14
REVIEW
Eqrem Rusi, Fiorenza Pennacchia, Wael Abu Ruqa, Giuseppina Talarico, Giuseppe Bruno, Antonio Minni, Christian Barbato
Background : Very little is known about the proteome of the human olfactory system and how diseases associated with olfactory dysfunctions can affect it. With this review, we try to summarize the existing literature on the use of this technique for a better understanding of the neurodegenerative disease process. Methods : We used the PubMed database and found different articles which were then selected independently by three authors. Results : We found 157 articles, of which, after careful selection, only 30 were analyzed in this review...
March 21, 2024: Proteomes
https://read.qxmd.com/read/38535438/hydroxytakakiamide-and-other-constituents-from-a-marine-sponge-associated-fungus-aspergillus-fischeri-mmeru23-and-antinociceptive-activity-of-ergosterol-acetate-acetylaszonalenin-and-helvolic-acid
#15
JOURNAL ARTICLE
Harol Ricardo Arias Cardona, Bruno Cerqueira da Silva, Flávia Oliveira de Lima, Franco Henrique Andrade Leite, Bruno Cruz de Souza, Hugo Neves Brandão, Jorge Maurício David, Clayton Queiroz Alves, Anake Kijjoa
An unreported prenylated indole derivative hydroxytakakiamide ( 4 ) was isolated, together with the previously described ergosterol ( 1 ), ergosterol acetate ( 2 ), and (3 R )-3-(1 H -indol-3-ylmethyl)-3, 4-dihydro-1 H -1,4-benzodiazepine-2,5-dione ( 3 ), from the column fractions of the crude ethyl acetate extract of the culture of a marine sponge-associated fungus, Aspergillus fischeri MMERU 23. The structure of 4 was elucidated by the interpretation of 1D and 2D NMR spectral data and high-resolution mass spectrum...
February 20, 2024: Marine Drugs
https://read.qxmd.com/read/38535402/odonata-assemblages-in-urban-semi-natural-wetlands
#16
JOURNAL ARTICLE
Marina Vilenica, Andreja Brigić, Ana Štih Koren, Toni Koren, Mirela Sertić Perić, Bruno Schmidt, Tomislava Bužan, Sanja Gottstein
As the human population in urban areas is continuously growing, urbanization is one of the greatest threats to biodiversity. To mitigate the negative effects, the inclusion of blue zones (aquatic habitats) in modern urban development practices is strongly recommended, as they could be beneficial for the local biodiversity conservation. Odonata are a flagship group and are widely used in freshwater conservation as ecological indicators of habitat integrity and health. However, our understanding of their ecological requirements in urban landscapes is not yet complete...
March 20, 2024: Insects
https://read.qxmd.com/read/38535344/response-of-chironomidae-diptera-to-ddt-mercury-and-arsenic-legacy-pollution-in-sediments-of-the-toce-river-northern-italy
#17
JOURNAL ARTICLE
Laura Marziali, Niccolò Pirola, Alfredo Schiavon, Bruno Rossaro
The Toce River (Northern Italy) is characterized by legacy contamination of dichloro-diphenyl-trichloroethane (DDT), mercury, and arsenic deriving from an industrial plant active between ca. 1915 and 1996. Chironomidae taxa assemblages and sediments were collected in 2014 and 2019 upstream and downstream of the industrial area to analyze species responses to toxic substances in a river stretch with relatively uniform natural (i.e., hydro-morphological) characteristics. A total of 32 chironomid taxa were identified...
February 22, 2024: Insects
https://read.qxmd.com/read/38535224/genome-comparisons-between-botrytis-fabae-and-the-closely-related-gray-mold-fungus-botrytis-cinerea-reveal-possible-explanations-for-their-contrasting-host-ranges
#18
JOURNAL ARTICLE
Klaus Klug, Pinkuan Zhu, Patrick Pattar, Tobias Mueller, Nassim Safari, Frederik Sommer, Claudio A Valero-Jiménez, Jan A L van Kan, Bruno Huettel, Kurt Stueber, David Scheuring, Michael Schroda, Matthias Hahn
While Botrytis cinerea causes gray mold on many plants, its close relative, Botrytis fabae , is host-specifically infecting predominantly faba bean plants. To explore the basis for its narrow host range, a gapless genome sequence of B. fabae strain G12 (BfabG12) was generated. The BfabG12 genome encompasses 45.0 Mb, with 16 chromosomal telomere-to-telomere contigs that show high synteny and sequence similarity to the corresponding B. cinerea B05.10 (BcB0510) chromosomes. Compared to BcB0510, it is 6% larger, due to many AT-rich regions containing remnants of transposable elements, but encodes fewer genes (11,420 vs...
March 14, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38535140/development-of-a-micro-ct-scanner-with-dual-energy-option-and-endovascular-contrast-agent-administration-protocol-for-fetal-and-neonatal-virtual-autopsy
#19
JOURNAL ARTICLE
Robert Zboray, Wolf Schweitzer, Lars Ebert, Martin Wolf, Sabino Guglielmini, Stefan Haemmerle, Stephan Weiss, Bruno Koller
The rate of parental consent for fetal and perinatal autopsy is decreasing, whereas parents are more likely to agree to virtual autopsy by non-invasive imaging methods. Fetal and perinatal virtual autopsy needs high-resolution and good soft-tissue contrast for investigation of the cause of death and underlying trauma or pathology in fetuses and stillborn infants. This is offered by micro-computed tomography (CT), as opposed to the limited resolution provided by clinical CT scanners, and this is one of the most promising tools for non-invasive perinatal postmortem imaging...
February 29, 2024: Journal of Imaging
https://read.qxmd.com/read/38535039/differential-effects-of-a-telemonitoring-platform-in-the-development-of-chemotherapy-associated-toxicity-a-randomized-trial-protocol
#20
JOURNAL ARTICLE
Felipe Martínez, Carla Taramasco, Manuel Espinoza, Johanna Acevedo, Carolina Goic, Bruno Nervi
Chemotherapy requires careful monitoring, but traditional follow-up approaches face significant challenges that were highlighted by the COVID-19 pandemic. Hence, exploration into telemonitoring as an alternative emerged. The objective is to assess the impact of a telemonitoring platform that provides clinical data to physicians overseeing solid tumor patients, aiming to enhance the care experience. The methodology outlines a parallel-group randomized clinical trial involving recently diagnosed patients with solid carcinomas preparing for curative intent chemotherapy...
March 14, 2024: Diagnostics
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