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https://www.readbyqxmd.com/read/28337729/adjacent-level-disease-background-and-update-based-on-disc-replacement-data
#1
REVIEW
I David Kaye, Alan S Hilibrand
PURPOSE OF REVIEW: The precise etiology of adjacent segment disease following cervical spine surgery is controversial. Theories for development include inevitable changes secondary to the natural progression of the degenerative cascade and changes secondary to altered biomechanics of the fused cervical spine. Motion preserving techniques, such as cervical disc arthroplasties (CDA), have been introduced with the hopes of reducing the rates of adjacent segment pathology. Recently, 7-year data from the investigational device exemption (IDE) studies have been published...
March 23, 2017: Current Reviews in Musculoskeletal Medicine
https://www.readbyqxmd.com/read/28336484/lumbar-mri-findings-in-patients-with-and-without-waddell-signs
#2
J S Cox, S Blizzard, H Carlson, J Hiratza, J U Yoo
BACKGROUND CONTEXT: Waddell Signs (WS), introduced as a method to establish patients with substantial psychosocial components to their low back pain, carry a negative association despite no literature evaluating whether physical disease is associated with them. PURPOSE: To compare lumbar MRI findings between the patients with and without Waddell's Signs. STUDY DESIGN: Retrospective cohort study based on prospectively collected data PATIENT SAMPLE: Thirty patients aged 35-55 with an ODI score >50 randomly selected such that there was an even distribution of patients based on number of WS OUTCOME MEASURES: ODI and SF-12 scores, number of WS, presence and severity of spinal pathology METHODS: MRIs were reviewed by three spine specialists blinded to clinical exam findings, number of WS, and patient identity...
March 20, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28332854/the-intravoxel-incoherent-motion-mri-of-lateral-pterygoid-muscle-a-quantitative-analysis-in-patients-with-temporomandibular-joint-disorders
#3
Supak Ngamsom, Shin Nakamura, Junichiro Sakamoto, Shinya Kotaki, Akemi Tetsumura, Tohru Kurabayashi
OBJECTIVES: To quantitatively evaluate diffusion and perfusion status of lateral pterygoid muscle (LPM) in patients with temporomandibular joint disorder (TMD) by intravoxel incoherent motion (IVIM) imaging and to correlate with findings on temporomandibular joints (TMJs) by conventional MRI. METHODS: 42 patients with TMD underwent MRI. To assess IVIM parameters, diffusion-weighted imaging was obtained by spin-echo-based single-shot echoplanar imaging. Regions of interest were created on all diffusion-weighted images of the superior belly of the lateral pterygoid (SLP) and inferior belly of the lateral pterygoid (ILP) at b-values 0-500 s mm(-2)...
March 23, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/28324865/biomaterials-for-intervertebral-disc-regeneration-and-repair
#4
REVIEW
Robert D Bowles, Lori A Setton
The intervertebral disc contributes to motion, weight bearing, and flexibility of the spine, but is susceptible to damage and morphological changes that contribute to pathology with age and injury. Engineering strategies that rely upon synthetic materials or composite implants that do not interface with the biological components of the disc have not met with widespread use or desirable outcomes in the treatment of intervertebral disc pathology. Here we review bioengineering advances to treat disc disorders, using cell-supplemented materials, or acellular, biologically based materials, that provide opportunity for cell-material interactions and remodeling in the treatment of intervertebral disc disorders...
March 15, 2017: Biomaterials
https://www.readbyqxmd.com/read/28321567/adjacent-segment-pathology-natural-history-or-effect-of-anterior-cervical-discectomy-and-fusion-a-10-year-follow-up-radiological-multicenter-study-using-an-evaluation-scale-of-the-ageing-spine
#5
Alessandro Pesce, Venceslao Wierzbicki, Emanuele Piccione, Alessandro Frati, Antonino Raco, Riccardo Caruso
PURPOSE: Aim of this study is to compare late degenerative MRI changes in a subset of patients operated on with ACDF to a second subset of patients presenting indication to ACDF but never operated on. METHODS: Patients from both subgroups received surgical indication according to the same criteria. Both subgroups underwent a cervical spine MRI in 2004-2005 and 10 years later in 2015. These MRI scans were retrospectively evaluated with a cervical spine ageing scale...
March 20, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28321351/bilateral-birdshot-retinochoroiditis-and-retinal-astrocytoma
#6
Sunil Mamtora, Yun Wong, Dugald Bell, Teresa Sandinha
Background. This case highlights the importance of recognising multiple pathologies within the eye which may not necessarily be linked. Both birdshot retinochoroiditis and astrocytoma are rare conditions. The case underlines the need for early identification and treatment of birdshot retinochoroiditis with steroids and disease modifying drugs. Astrocytoma in the absence of tuberous sclerosis is also uncommon. Case Presentation. A 36-year-old male presented with 3-month history of bilateral progressive flashing lights and floaters...
2017: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/28291195/-optic-nerve-pathology-in-the-structure-of-diagnostic-errors-inpatients-referred-for-cataract-surgery
#7
V V Egorov, N V Savchenko, E L Sorokin, O V Danilov
AIM: to study the frequency of misdiagnosis of cataract in patients with optic nerve pathology or amblyopia and to identify its main causes. MATERIAL AND METHODS: The study enrolled 381 patients (381 eyes) wrongly diagnosed with cataract. A standard set of eye tests was performed. In-depth examination of the macular area was done through biomicroscopy with contactless aspheric lenses of 60 and 90 D. Part of the patients underwent optical coherence tomography and static perimetry as well as examination of electrical sensitivity threshold and electrical lability of the optic nerve...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28290310/a-secondary-mandibular-condylar-articulation-and-collateral-effects-on-a-late-neolithic-mandible-from-bois-madame-rockshelter-in-arbre-belgium
#8
Frank L'Engle Williams, Caroline Polet
A Neolithic Belgian mandible from Bois Madame rockshelter in Arbre presents an asymmetrical morphology resulting from a secondary, or false, articulation of the right mandibular condyle. The pathological articulation produced enlarged masseter, medial pterygoid and mylohyoid musculature on the right side as well as a flattening of the right incisal alveolus curvature. The secondary condylar articulation did not lead to pronounced asymmetry of attrition on the antimeres of the dental arcade. This is the most complete mandible from this Late Neolithic collective burial dating to the beginning of the Bronze Age circa 4000 years BP...
March 2017: International Journal of Paleopathology
https://www.readbyqxmd.com/read/28289843/micro-ct-evaluation-of-asymmetrical-ovine-intervertebral-disc-height-loss-from-surgical-approach
#9
Christopher Ludtka, Stefan Schwan, Andrea Friedmann, Walther Brehm, Ingo Wiesner, Felix Goehre
PURPOSE: The primary goal of this study is to clearly define and evaluate new intervertebral disc height parameters in analysing the morphological pathology of disc degeneration for application in damage model and regeneration therapy development, as well as applying traditional variables to 3-D characterization methods. METHODS: A posterolateral surgical approach was used to induce disc degeneration in an ovine model. At 12-months post-operation, sheep vertebral segments were removed and characterized using micro-CT to evaluate disc height parameters in regard to injury localization...
March 13, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28288337/remodelling-of-myocardial-intercalated-disc-protein-connexin-43-causes-increased-susceptibility-to-malignant-arrhythmias-in-arvc-d-patients
#10
Xiao Chen, Liang Chen, Zhenglian Chen, Xinshan Chen, Jiangping Song
BACKGROUND: Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is a primary cardiomyopathy characterised by fibrofatty replacement and ventricular arrhythmias. The occurrence of malignant arrhythmias may be associated with fatty infiltration and intercalated disk remodelling, but the specific pathological remodelling pattern is not yet clear. METHODS: Twelve explanted hearts from patients diagnosed with ARVC/D according to the 2010 Task Force Criteria and pathology examination were divided into two groups with (SVT, n=6) or without (non-SVT, n=6) recurrent sustained ventricular tachycardia (SVT) before heart transplantation...
February 27, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28279769/lumbar-facet-tropism-a-comprehensive-review
#11
REVIEW
Fernando Alonso, Christina M Kirkpatrick, William Jeong, Christian Fisahn, Sameera Usman, Tarush Rustagi, Marios Loukas, Jens R Chapman, Rod J Oskouian, R Shane Tubbs
Scattered reports exist in the medical literature regarding facet tropism. However, this finding has had mixed conclusions regarding its origin and impact on the normal spine. Herein, we review the anatomy, embryology, biomechanics, and pathology related to lumbar facet tropism. Facet tropism is most commonly found at L4-L5 vertebral segments and there is some evidence that this condition may lead to facet degenerative spondylolisthesis, intervertebral disc disease, and other degenerative conditions.
March 6, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28279053/-intra-articular-injections-of-hyaluronic-acid-for-anterior-disc-displacement-of-temporomandibular-joint
#12
X Long
Anterior disc displacement (ADD) of temporomandibular joint (TMJ) is regarded as one of the major findings in temporomandibular disorders (TMD). It is related to joint noise, pain, mandibular dysfunction, degenerative change and osteoarthritis. In the mean time, the pathological changes were found in synovial membrane and synovial fluid. Hyaluronic acid is a principal component of the synovial fluid which plays an important role in nutrition, lubrication, anti-inflammation and cartilage repair. The synthesis, molecule weight, and concentration of hyaluronic acid are decreased during TMD and cause TMJ degenerative changes...
March 9, 2017: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/28270999/fully-automated-diagnosis-of-papilledema-through-robust-extraction-of-vascular-patterns-and-ocular-pathology-from-fundus-photographs
#13
Khush Naseeb Fatima, Taimur Hassan, M Usman Akram, Mahmood Akhtar, Wasi Haider Butt
Rapid development in the field of ophthalmology has increased the demand of computer aided diagnosis of various eye diseases. Papilledema is an eye disease in which the optic disc of the eye is swelled due to an increase in intracranial pressure. This increased pressure can cause severe encephalic complications like abscess, tumors, meningitis or encephalitis, which may lead to a patient's death. Although there have been several papilledema case studies reported from a medical point of view, only a few researchers have presented automated algorithms for this problem...
February 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28269794/myofibrillar-myopathies-new-perspectives-from-animal-models-to-potential-therapeutic-approaches
#14
Sabrina Batonnet-Pichon, Anthony Behin, Eva Cabet, Florence Delort, Patrick Vicart, Alain Lilienbaum
Myofibrillar myopathies (MFMs) are muscular disorders involving proteins that play a role in the structure, maintenance processes and protein quality control mechanisms closely related to the Z-disc in the muscular fibers. MFMs share common histological characteristics including progressive disorganization of the interfibrillar network and protein aggregation. Currently no treatment is available. In this review, we describe first clinical symptoms associated with mutations of the six genes (DES, CRYAB, MYOT, ZASP, FLNC and BAG3) primary involved in MFM and defining the origin of this pathology...
2017: Journal of Neuromuscular Diseases
https://www.readbyqxmd.com/read/28268998/mapping-the-retinas-of-a-patient-using-a-mixed-set-of-fundus-photographs-from-both-eyes
#15
Gwenole Quellec, Mathieu Lamard, Guy Cazuguel, Ali Erginay, Beatrice Cochener
With the increased prevalence of retinal pathologies, automating the detection and progression measurement of these pathologies is becoming more and more relevant. Color fundus photography is the leading modality for assessing retinal pathologies. Because eye fundus cameras have a limited field of view, multiple photographs are taken from each retina during an eye fundus examination. However, operators usually don't indicate which photographs are from the left retina and which ones are from the right retina...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28267905/-results-of-percutaneous-discectomy-in-the-management-of-lumbar-disc-herniation
#16
P G Lima-Ramírez, A J Montiel-Jarquín, R G Barragán-Hervella, M A Sánchez-Durán, A Ochoa-Neri, J Loria-Castellanos, C Vázquez-Rodríguez, A Villatoro-Martínez, J J Castillo-Pérez
INTRODUCTION: Percutaneous discectomy is a disc decompression technique approved by the FDA that is useful to improve pain caused by a herniated disc. However, its practice is under discussion because the benefits of the technique are controversial. OBJECTIVES: To describe the clinical course of patients with low lumbar disc herniation (L4-L5, L5-S1) treated by percutaneous surgery within one year of surgery and prove that it is a useful surgical option for the relief of symptoms caused by this pathological entity...
July 2016: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/28266008/phantom-radicular-pain-treated-with-lumbar-microdiscectomy-a-case-report
#17
Orkun Koban, Ahmet Öğrenci, Onur Yaman, Sedat Dalbayrak
Phantom limb pain in amputee patients is not well defined in the literature. Also there is still no clear information on the definition and treatment of phantom radicular pain, in which amputee patients also have radicular pain. This phenomenon, called phantom radiculitis or phantom radiculopathy, has been described in a limited number of cases. If a pathological condition to cause radicular pain is present in patients with amputee, the phantom pain\'s degree is increasing. Degenerative disc diseases are the most common cause of phantom radicular pain...
February 15, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28259264/mri-screening-in-operative-scheuermann-kyphosis-is-it-necessary
#18
Baron S Lonner, Courtney S Toombs, Michael Mechlin, Gina Ciavarra, Suken A Shah, Amer F Samdani, Paul Sponseller, Harry L Shufflebarger, Randal R Betz, Burt Yaszay, Peter O Newton
STUDY DESIGN: Patients with preoperative spine magnetic resonance imaging (MRI) studies from a prospective multicenter study of operative adolescent Scheuermann kyphosis (SK). OBJECTIVES: To investigate the usefulness of MRI screening in operative planning for SK surgeries. SUMMARY OF BACKGROUND DATA: Neural axis abnormalities in operative SK have not been previously studied with MRI screening, despite its use. METHODS: One orthopedic surgeon and two radiologists evaluated all images retrospectively...
March 2017: Spine Deformity
https://www.readbyqxmd.com/read/28253483/factors-that-influence-recurrent-lumbar-disc-herniation
#19
M E Yaman, A Kazancı, N D Yaman, F Baş, G Ayberk
INTRODUCTION: The most common cause of poor outcome following lumbar disc surgery is recurrent herniation. Recurrence has been noted in 5% to 15% of patients with surgically treated primary lumbar disc herniation. There have been many studies designed to determine the risk factors for recurrent lumbar disc herniation. In this study, we retrospectively analysed the influence of disc degeneration, endplate changes, surgical technique, and patient's clinical characteristics on recurrent lumbar disc herniation...
March 3, 2017: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/28252425/-features-of-the-treatment-of-the-spine-in-rheumatoid-arthritis
#20
S Selezneva, O Sinyachenko, А Zabara
Rheumatoid arthritis (RA) refers to the most common inflammatory joint disease, which can lead to persistent disability and early mortality of patients, and one of the manifestations of RA is a frequent lesion of the spine, which significantly affects the quality of life of these patients. OBJECTIVE: To evaluate spine lesion in patients with different types of current RA and factors that determine it. MATERIAL AND METHODS: Under the supervision of the RA patient 131 was aged 18 to 79 years (mean 45 years) among them was 18% male and 82% female...
January 2017: Georgian Medical News
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