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Palliative gastrectomy

Xue-Ru Zhu, Mei-Ling Zhu, Qing Wang, Wen-Ji Xue, Yi-Wei Wang, Rui-Fen Wang, Si-Yu Chen, Lei-Zhen Zheng
BACKGROUND: Alpha-fetoprotein (AFP) is an important marker for hepatocellular carcinoma, and the detection of serum AFP is currently the principle method for the diagnosis of hepatocellular carcinoma. The prevalence of gastric cancer (GC) with high level of serum AFP is extremely rare, but has unique clinical features. CASE SUMMARY: We herein present a rare case with GC and high level of serum AFP. A 64-year-old Chinese female underwent gastrectomy was diagnosed as gastric adenocarcinoma and the pathological stage was T1bN0M0, IA...
September 2016: Medicine (Baltimore)
Jasbir Makker, Niraj Karki, Binita Sapkota, Masooma Niazi, Prospere Remy
BACKGROUND Gastroesophageal cancers, previously considered rare, are rapidly increasing worldwide. We present here a unique case of gastroesophageal carcinoma with metastasis to the rectum. CASE REPORT A 60-year-old female patient presented with constipation, bloating, and weight loss of 4-month duration. She had undergone sleeve gastrectomy 6 years before. Endoscopies performed revealed a friable-looking mucosa in the lower esophagus and a polypoid rectal mass. Histopathological examination from both the esophageal and rectal lesions revealed poorly differentiated adenocarcinoma cells...
August 25, 2016: American Journal of Case Reports
Xuefeng Yu, Fulan Hu, Qiang Yao, Chunfeng Li, Hongfeng Zhang, Yingwei Xue
BACKGROUND: Platelet and blood coagulation abnormalities frequently occur in cancer patients. Fibrinogen is an important hemostatic factor that regulates the hemostatic pathway. Hyperfibrinogenemia is increasing recognized as an important risk factor influencing cancer development and outcome. However, few reports have investigated the prognostic potential of fibrinogen for predicting the survival of gastric cancer (GC) patients. The primary aim of this study was to evaluate the usefulness of preoperative serum fibrinogen as a biomarker for predicating tumor progression and survival of patients with GC...
2016: BMC Cancer
Run-Cong Nie, Shi Chen, Shu-Qiang Yuan, Xiao-Jiang Chen, Yong-Ming Chen, Bao-Yan Zhu, Hai-Bo Qiu, Jun-Sheng Peng, Ying-Bo Chen
OBJECTIVE: The aim of this study was to explore whether palliative gastrectomy is suitable for gastric cancer patients with peritoneal metastasis, and for patients in whom the type of peritoneal metastasis should be selected to receive palliative gastrectomy. METHODS: A total of 747 patients diagnosed with gastric adenocarcinoma with peritoneal metastasis at our centers between January 2000 and April 2014 were retrospectively analyzed. After propensity score matching, the clinicopathologic characteristics and clinical outcomes of patients with peritoneal dissemination were analyzed...
July 5, 2016: Annals of Surgical Oncology
Mériam Sabbah, Norsaf Bibani, Dalila Gargouri, Dorra Trad, Asma Ouakaa, Hela Elloumi, Asma Kochlef, Jamel Kharrat
INTRODUCTION: Cutaneous metastasis of gastric tumors are very rare. Their topography is generally near to the primitive tumor, in the abdominal wall but rarely in cervical region. AIM: the aim of our study was to describe the topography and the clinic-pathological characteristics of cutaneous metastasis of ring cells gastric adenocarcinoma. Observation1: Our first patient is aged of 33 years has epigastralgias and vomiting. Gastric adenocarcinoma with independent cells was diagnosed by gastroscopy and gastric biopsy made for gastric pain and loss of weigh...
August 2015: La Tunisie Médicale
Jung Eun Choi, A Reum Choe, Sang Eun Yoon, Eun Mi Nam, Heejung Park, Kyoung Eun Lee
The most common sites for extragonadal germ cell tumors are the midline mediastinum, retroperitoneum and, much less frequently, the stomach. The stomach-originated primary germ cell tumor carries a poor prognosis, especially when metastasis occurs to the liver, with a mean survival time of 1 month. We describe the case of a 77-year-old male who presented with usual symptoms of gastric malignancy. Gastrectomy was performed. Histopathology of surgically resected tissue revealed a mixture of adenocarcinoma and endodermal sinus tumor components with α-fetoprotein production...
June 29, 2016: Chemotherapy
T Boerner, A Graichen, T Jeiter, F Zemann, P Renner, L März, Y Soeder, H J Schlitt, P Piso, M H Dahlke
PURPOSE: Peritoneal carcinomatosis (PC) is a dismal feature of gastric cancer that most often is treated by systemic palliative chemotherapy. In this retrospective matched pairs-analysis, we sought to establish whether specific patient subgroups alternatively should be offered a multimodal therapy concept, including cytoreductive surgery (CRS) and intraoperative hyperthermic chemotherapy (HIPEC). METHODS: Clinical outcomes of 38 consecutive patients treated with gastrectomy, CRS and HIPEC for advanced gastric cancer with PC were compared to patients treated by palliative management (with and without gastrectomy) and to patients with advanced gastric cancer with no evidence of PC...
June 16, 2016: Annals of Surgical Oncology
Alexandra W Acher, Malcolm H Squires, Ryan C Fields, George A Poultsides, Carl Schmidt, Konstantinos I Votanopoulos, Timothy M Pawlik, Linda X Jin, Aslam Ejaz, David A Kooby, Mark Bloomston, David Worhunsky, Edward A Levine, Neil Saunders, Emily Winslow, Clifford S Cho, Glen Leverson, Shishir K Maithel, Sharon M Weber
BACKGROUND: This study utilized a multi-institutional database to evaluate risk factors for readmission in patients undergoing curative gastrectomy for gastric adenocarcinoma with the intent of describing both perioperative risk factors and the relationship of readmission to survival. METHODS: Patients who underwent curative resection of gastric adenocarcinoma from 2000 to 2012 from seven academic institutions of the US Gastric Cancer Collaborative were analyzed...
July 2016: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
Kanefumi Yamashita, Shinsuke Takeno, Satoshi Nimura, Yoshikazu Sugiyama, Takayuki Sueta, Kenji Maki, Yoshiyuki Kayashima, Hironari Shiwaku, Daisuke Kato, Tatsuya Hashimoto, Takamitsu Sasaki, Yuichi Yamashita
INTRODUCTION: We present a very rare case of gastric metastasis mimicking primary gastric cancer in a patient who had undergone surgery for salivary duct carcinoma. PRESENTATION OF CASE: A 67-year-old man had been diagnosed as having right parotid cancer and had undergone a right parotidectomy and lymph node dissection. The histological diagnosis was salivary duct carcinoma. One year after the surgery, a positron emission tomography-computed tomography scan using fluorodeoxyglucose (FDG) revealed an abnormal uptake of FDG in the left cervical, mediastinal, paraaortic, and cardiac lymph nodes; stomach; and pancreas...
2016: International Journal of Surgery Case Reports
Tomohiko Setoguchi, Toshiya Akai, Kenichi Sunayama, Toshiyuki Ori
An 82-year-old man with far-advanced gastric cancer underwent palliative distal gastrectomy. After operation, he was treated with S-1 therapy and maintained stable disease during 3 courses of chemotherapy. However, he stopped taking the drug according to self-judgment. After that, he was admitted to our hospital because of jaundice and general malaise. We diagnosed oncologic emergency with liver metastasis. He was treated with weekly nanoparticle albumin-bound paclitaxel. After 1 course of chemotherapy, his symptoms were improved and he was discharged...
March 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Masahide Ikeguchi, Kozo Miyatani, Seigo Takaya, Tomoyuki Matsunaga, Youji Fukumoto, Tomohiro Osaki, Hiroaki Saito, Toshiro Wakatsuki
Optimal treatment of patients with gastric cancer with synchronous distant metastases is palliative chemotherapy. However, occasionally gastrectomy should be selected due to control bleeding from tumors, perforation, or obstruction. The aim of this study is to evaluate the survival benefits of non-curative gastrectomy for patients with synchronous distant metastasis. Total 78 gastric cancer patients with synchronous distant metastasis treated in our hospital between 2003 and 2012 were enrolled in this study...
March 2016: Indian Journal of Surgical Oncology
Kunihiko Izuishi, Hirohito Mori
Recently, many strategies have been reported for the effective treatment of gastric cancer. However, the strategy for treating stage IV gastric cancer remains controversial. Conducting a prospective phase III study in stage IV cancer patients is difficult because of heterogeneous performance status, age, and degree of cancer metastasis or extension. Due to poor prognosis, the variance in physical status, and severe symptoms, it is important to determine the optimal strategy for treating each individual stage IV patient...
March 2016: Journal of Gastrointestinal and Liver Diseases: JGLD
E A Godzhello, M V Khrustaleva, R D Sharipzhanova, M A Dekhtyar
INTRODUCTION: Gastroduodenal, enteral and colorectal stenting of blastomatous stenosis is a reasonable alternative to operative treatment of unresectable tumors. Moreover in some cases it allows to gain time and to prepare the patient for radical surgery. MATERIAL AND METHODS: For the period from 2007 to 2015 in endoscopic department of acad. B.V. Petrovskiy Russian Research Center for Surgery 76 patients with piloroduodenal, enteral and colic stenoses successfully underwent self-expanding metal stents installation...
2015: Khirurgiia
Sheraz R Markar, Hugh Mackenzie, Sameh Mikhail, Muntzer Mughal, Shaun R Preston, Nick D Maynard, Omar Faiz, George B Hanna
BACKGROUND: The objectives of this national study were to examine the short-term safety and long-term survival benefit associated with surgical resection of hepatic metastases from gastric cancer. METHODS: Patients from the Hospital Episode Statistics database were classified by disease and treatment approach. Gastric cancer: 1. Without liver metastases treated by gastrectomy (GG). 2. With liver metastases treated by gastrectomy and hepatectomy (GGH). 3. With liver metastases treated by gastrectomy without hepatectomy (GGNH)...
March 3, 2016: Gastric Cancer
Sohei Matsumoto, Tomoyoshi Takayama, Kohei Wakatsuki, Tetsuya Tanaka, Kazuhiro Migita, Masahiro Ito, Yoshiyuki Nakajima
BACKGROUND/AIMS: The aim of this study was to evaluate the surgical outcomes after palliative surgery for patients with incurable gastric cancer. METHODOLOGY: This retrospective study included 45 patients with gastric outlet obstruction (GOO) who needed parental nutrition and 33 patients with anemia due to tumor bleeding who required blood transfusions. We compared the surgical outcomes of palliative gastrectomy (PG) and bypass surgery (BS) in each group. RESULTS: In the GOO patients, the clinical success rate, as indicated by a resumption of an oral diet, was similar in the PG and BS groups...
June 2015: Hepato-gastroenterology
Feng Tao, Jieqing Lv, Wei Wang, Ketao Jin
The best treatment for gastric cancer hepatic metastasis is still widely debated. Gastric cancer hepatic metastases has long been justified the indication of palliative chemotherapy. Inspired by the good results of the management of colorectal cancer hepatic metastases, surgeons have focused on the curative or palliative treatment of gastric cancer hepatic metastases. The current clinical modalities used for treatment of gastric cancer hepatic metastasis include liver resection, systemic chemotherapy, radiofrequency ablation (RFA), hepatic arterial infusion (HAI), and palliative gastrectomy...
2015: International Journal of Clinical and Experimental Medicine
Jesús Espinel, Eugenia Pinedo, Vanesa Ojeda, María Guerra-del-Río
No abstract text is available yet for this article.
February 2016: Revista Española de Enfermedades Digestivas
Elena Zucchi, Mara Fornasarig, Luca Martella, Stefania Maiero, Emilio Lucia, Eugenio Borsatti, Luca Balestreri, Giorgio Giorda, Maria Antonietta Annunziata, Renato Cannizzaro
PURPOSE: The purpose of this study was to evaluate patient-centered outcomes of decompressive percutaneous endoscopic gastrostomy (dPEG) in patients with malignant bowel obstruction due to advanced gynecological and gastroenteric malignancies. METHODS: This is a prospective analysis of 158 consecutive patients with small-bowel obstruction from advanced gynecological and gastroenteric cancer who underwent PEG or percutaneous endoscopic jejunostomy (PEJ) positioning for decompressive purposes from 2002 to 2012...
July 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Wei Wang, Zhe Sun, Jingyu Deng, Zhenning Wang, Zhiwei Zhou, Han Liang, Huimian Xu
OBJECTIVE: To elucidate the current diagnosis and treatment status of gastric cancer in the Chinese population based on three high volume databases. METHODS: Clinical and pathological data of patients who underwent gastric cancer resection with complete follow-up information between January 2000 and December 2012 from Sun Yat-sen University Cancer Center, The First Affiliated Hospital of China Medical University and Tianjin Medical University Cancer Hospital were retrospectively analyzed...
February 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
Johannes J Nel, Cornelius J du Plessis, Gert L Coetzee
A nine-year-old female Rottweiler with a history of repeated gastrointestinal ulcerations and three previous surgical interventions related to gastrointestinal ulceration presented with symptoms of anorexia and intermittent vomiting. Benign gastric outflow obstruction was diagnosed in the proximal duodenal area. The initial surgical plan was to perform a pylorectomy with gastroduodenostomy (Billroth I procedure), but owing to substantial scar tissue and adhesions in the area a palliative gastrojejunostomy was performed...
2015: Journal of the South African Veterinary Association
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