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https://www.readbyqxmd.com/read/28464806/the-effect-of-ocular-biometric-factors-on-the-accuracy-of-various-iol-power-calculation-formulas
#1
Jinho Jeong, Han Song, Jimmy K Lee, Roy S Chuck, Ji-Won Kwon
BACKGROUND: To evaluate how differences in ocular biometry affects the Hoffer Q, Holladay 1, SRK/T, and Haigis intraocular lens power calculation formulae predictions. METHODS: This study was performed on 91 eyes of 91 patients who underwent uneventful cataract surgery. Ocular biometry values were measured using the IOL Master 500, and intraocular lens (IOL) power was calculated using the Haigis, Hoffer Q, Holladay 1, and SRK/T formulas. We calculated the expected difference (ED) of each 3rd generation formula from the Haigis formula by subtracting the predicted refraction of the Haigis formula from the predicted refraction of each 3rd generation formula...
May 2, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28461247/systemic-antimir-337-3p-delivery-inhibits-cerebral-ischemia-mediated-injury
#2
Xiaomin Wang, Yalikun Suofu, Berkcan Akpinar, Sergei V Baranov, Jinho Kim, Diane L Carlisle, Yu Zhang, Robert M Friedlander
Modulation of miRNA expression has been shown to be beneficial in the context of multiple diseases. The purpose of this study was to determine if an inhibitor of miR-337-3p is neuroprotective for hypoxic injury after tail vein injection. We evaluated miR-337-3p expression levels and in brain tissue in vivo before and after permanent middle cerebral artery occlusion (pMCAO) in mice. Subsequently, a custom locked nucleic acid (LNA) antimir-337-3p oligonucleotide was developed and tested in vitro after induction of oxygen glucose-deprivation (OGD) and in vivo by injection into the mouse tail vein for 3 consecutive days before pMCAO...
April 28, 2017: Neurobiology of Disease
https://www.readbyqxmd.com/read/28456260/improved-design-for-a-low-temperature-scanning-tunneling-microscope-with-an-in-situ-tip-treatment-stage
#3
J-J Kim, S H Joo, K S Lee, J H Yoo, M S Park, J S Kwak, Jinho Lee
The Low Temperature Scanning Tunneling Microscope (LT-STM) is an extremely valuable tool not only in surface science but also in condensed matter physics. For years, numerous new ideas have been adopted to perfect LT-STM performances-Ultra-Low Vibration (ULV) laboratory and the rigid STM head design are among them. Here, we present three improvements for the design of the ULV laboratory and the LT-STM: tip treatment stage, sample cleaving stage, and vibration isolation system. The improved tip treatment stage enables us to perform field emission for the purpose of tip treatment in situ without exchanging samples, while our enhanced sample cleaving stage allows us to cleave samples at low temperature in a vacuum without optical access by a simple pressing motion...
April 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28441862/spatial-temporal-dispersion-of-aerosolized-nanoparticles-during-the-use-of-consumer-spray-products-and-estimates-of-inhalation-exposure
#4
Jihoon Park, Seunghon Ham, Miyeon Jang, Jinho Lee, Sunju Kim, Sungkyoon Kim, Kiyoung Lee, Donguk Park, Jung-Taek Kwon, Hyunmi Kim, Pilje Kim, Kyunghee Choi, Chungsik Yoon
We evaluated the spatial-temporal dispersion of airborne nanomaterials during the use of spray consumer products and estimated the level of consumer inhalation exposure. A total of eight spray products including five propellant and three pump types were selected to evaluate the dispersion of airborne nanoparticles across time and space in a cleanroom which could control the background particles. Four products were advertised to contain silver and one contained titanium nanoparticles, while three products were specified no ENM but as being manufactured through the use of nanotechnology...
April 25, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28417009/revised-definition-of-predicted-left-ventricular-mass-using-ambulatory-blood-pressure-in-healthy-korean-adults
#5
Bae Keun Kim, Enshi Xu, Bo Youl Choi, Yonggu Lee, Soon Gil Kim, Yukio Yamori, Jinho Shin
BACKGROUND: Left ventricular hypertrophy is influenced by both hemodynamic and non-hemodynamic factors. Ambulatory blood pressure is correlated with left ventricular hypertrophy. We established the influences of hemodynamic and non-hemodynamic factors, including ambulatory blood pressure, on variation in left ventricular mass in healthy Korean adults. METHOD: We included 172 subjects (male = 71, female = 101), with normal body mass index and blood pressure, in an analysis of data from the Yangpyung and Yeoju cohort studies and a tertiary cardiovascular center...
2017: Clinical Hypertension
https://www.readbyqxmd.com/read/28394417/achieving-large-area-planar-perovskite-solar-cells-by-introducing-an-interfacial-compatibilizer
#6
Jinho Lee, Hongkyu Kang, Geunjin Kim, Hyungcheol Back, Junghwan Kim, Soonil Hong, Byoungwook Park, Eunhag Lee, Kwanghee Lee
Despite the recent unprecedented increase in the power conversion efficiencies (PCEs) of small-area devices (≤0.1 cm(2) ), the PCEs deteriorate drastically for PSCs of larger areas because of the incomplete film coverage caused by the dewetting of the hydrophilic perovskite precursor solutions on the hydrophobic organic charge-transport layers (CTLs). Here, an innovative method of fabricating scalable PSCs on all types of organic CTLs is reported. By introducing an amphiphilic conjugated polyelectrolyte as an interfacial compatibilizer, fabricating uniform perovskite films on large-area substrates (18...
April 10, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28368124/development-of-surface-variable-polymeric-nanoparticles-for-drug-delivery-to-tumors
#7
Ning Han, Liang Pang, Jun Xu, Hyesun Hyun, Jinho Park, Yoon Yeo
To develop nanoparticle drug carriers that interact with cells specifically in the mildly acidic tumor microenvironment, we produced polymeric nanoparticles modified with amidated TAT peptide via a simple surface modification method. Two types of core poly(lactic-co-glycolic acid) nanoparticles (NL and NP) were prepared with a phospholipid shell as an optional feature and covered with polydopamine that enabled the conjugation of TAT peptide on the surface. Subsequent treatment with acid anhydrides such as cis-aconitic anhydride (CA) and succinic anhydride (SA) converted amines of lysine residues in TAT peptide to β-carboxylic amides, introducing carboxylic groups that undergo pH-dependent protonation and deprotonation...
April 11, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28351389/quality-of-medical-service-patient-satisfaction-and-loyalty-with-a-focus-on-interpersonal-based-medical-service-encounters-and-treatment-effectiveness-a-cross-sectional-multicenter-study-of-complementary-and-alternative-medicine-cam-hospitals
#8
MULTICENTER STUDY
Chang Eun Kim, Joon-Shik Shin, Jinho Lee, Yoon Jae Lee, Me-Riong Kim, Areum Choi, Ki Byung Park, Ho-Joo Lee, In-Hyuk Ha
BACKGROUND: Treatment effectiveness holds considerable importance in the association between service quality and satisfaction in medical service studies. While complementary and alternative medicine (CAM) use grows more prominent, comprehensive evaluations of the quality of medical service at CAM-oriented hospitals are scarce. This study assesses the quality of medical services provided at a CAM-oriented hospital of Korean medicine using the service encounter system approach and analyzes the influence of treatment effectiveness on patient loyalty...
March 28, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28337334/correction-to-chiral-cyclohexane-1-3-diones-as-inhibitors-of-mutant-sod1-dependent-protein-aggregation-for-the-treatment-of-als
#9
Yinan Zhang, Radhia Benmohamed, Wei Zhang, Jinho Kim, Christina K Edgerly, Yaoqiu Zhu, Richard I Morimoto, Robert J Ferrante, Donald R Kirsch, Richard B Silverman
[This corrects the article DOI: 10.1021/ml3000963.].
March 9, 2017: ACS Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28317979/fluorescent-bioimaging-of-ph-from-design-to-applications
#10
Ji-Ting Hou, Wen Xiu Ren, Kun Li, Jinho Seo, Amit Sharma, Xiao-Qi Yu, Jong Seung Kim
Protons play crucial roles in many physiological and pathological processes, such as receptor-mediated signal transduction, ion transport, endocytosis, homeostasis, cell proliferation, and apoptosis. The urgent demand for pH imaging and measurement in biological systems has incited the development of fluorescent pH probes. Numerous fluorescent probes have been reported, but many lack the abilities needed for biological applications. Hence, the development of new pH probes with better biocompatibility, sensitivity, and site-specificity is still indispensable...
April 18, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/28290161/corticosteroids-for-tuberculous-pleurisy
#11
REVIEW
Hannah Ryan, Jinho Yoo, Padmapriya Darsini
BACKGROUND: Corticosteroids used in addition to antituberculous therapy have been reported to benefit people with tuberculous pleurisy. However, research findings are inconsistent and raise doubt as to whether such treatment is worthwhile. There is also concern regarding the potential adverse effects of corticosteroids, especially in HIV-positive people. OBJECTIVES: To evaluate the effects of adding corticosteroids to drug regimens for tuberculous pleural effusion...
March 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28282797/relief-of-knee-flexion-contracture-and-gait-improvement-following-adaptive-training-for-an-assist-device-in-a-transtibial-amputee-a-case-study
#12
Sol-Bi Kim, Chang-Yong Ko, Jinho Son, Sungjae Kang, Jeicheong Ryu, Museong Mun
BACKGROUND: Management of a knee contracture is important for regaining gait ability in transtibial amputees. However, there has been little study of prosthesis training for enhancing mobility and improving range of motion in cases of restricted knee extension. OBJECTIVE: This study aimed to evaluate the effects of adaptive training for an assist device (ATAD) for a transtibial amputee with a knee flexion contracture (KFC). A male transtibial amputee with KFC performed 4 months of ATAD with a multidisciplinary team...
2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28278133/a-flat-panel-shaped-hybrid-piezo-triboelectric-nanogenerator-for-ambient-energy-harvesting
#13
Gul Hassan, Fasihullah Khan, Arshad Hassan, Shawkat Ali, Jinho Bae, Chong Hyun Lee
Recently, many researchers have been paying attention to nanogenerators (NGs) as energy sources for self-powered mirco-nano systems, and studying how to achieve their higher power generation. Hence, we propose a hybrid-type NG for harvesting both the piezoelectric and triboelectric effect simultaneously. In the proposed hybrid NG, the piezoelectric NG (PNG) and triboelectric NG (TENG) are fabricated using polydimethylsiloxane (PDMS) and perovskite zinc stannite (ZnSnO3) nanocubes with a high charge polarization of 59 uC cm(-2) composite (PDMS + ZnSnO3) and UV surface-treated PDMS, respectively...
April 28, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28266665/a-self-assembled-ni-cyclam-btc-network-on-ito-for-an-oxygen-evolution-catalyst-in-alkaline-solution
#14
Yun Jin Leem, Keumnam Cho, Kyung Hee Oh, Sung-Hwan Han, Ki Min Nam, Jinho Chang
A self-assembled Ni(cyclam)-BTC film was formed on ITO in an acidic solution. Ni(cyclam)-BTC exhibited an enhanced electro-catalytic property for the oxygen evolution reaction (OER), which was strongly relevant to the Ni(iii)/Ni(iv) redox reaction activated by the potential dynamic process. A possible formation mechanism of Ni(cyclam)-BTC by self-assembly on ITO was also proposed.
March 25, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28155879/synergistic-effect-of-indium-and-gallium-co-doping-on-growth-behavior-and-physical-properties-of-hydrothermally-grown-zno-nanorods
#15
Jun Hyung Lim, Seung Muk Lee, Hyun-Suk Kim, Hyun You Kim, Jozeph Park, Seung-Boo Jung, Geun Chul Park, Jungho Kim, Jinho Joo
We synthesized ZnO nanorods (NRs) using simple hydrothermal method, with the simultaneous incorporation of gallium (Ga) and indium (In), in addition, investigated the co-doping effect on the morphology, microstructure, electronic structure, and electrical/optical properties. The growth behavior of the doped NRs was affected by the nuclei density and polarity of the (001) plane. The c-axis parameter of the co-doped NRs was similar to that of undoped NRs due to the compensated lattice distortion caused by the presence of dopants that are both larger (In(3+)) and smaller (Ga(3+)) than the host Zn(2+) cations...
February 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28129399/long-term-course-of-failed-back-surgery-syndrome-fbss-patients-receiving-integrative-korean-medicine-treatment-a-1-year-prospective-observational-multicenter-study
#16
Jinho Lee, Joon-Shik Shin, Yoon Jae Lee, Me-Riong Kim, Areum Choi, Jun-Hwan Lee, Kyung-Min Shin, Byung-Cheul Shin, Jae-Heung Cho, In-Hyuk Ha
BACKGROUND: With increase of spine surgeries, failed back surgery syndrome (FBSS) prevalence is also rising. While complementary and alternative medicine (CAM) is commonly used for low back pain (LBP), there are no studies reporting use of integrative Korean medicine in FBSS patients. METHODS: Patients with pain continuing after back surgery or recurring within 1 year and visual analogue scale (VAS) of LBP or leg pain of ≥6 (total n = 120) were recruited at 2 hospital sites from November 2011 to September 2014...
2017: PloS One
https://www.readbyqxmd.com/read/28106392/anti-osteoporotic-activity-of-harpagoside-by-upregulation-of-the-bmp2-and-wnt-signaling-pathways-in-osteoblasts-and-suppression-of-differentiation-in-osteoclasts
#17
Hwa-Jin Chung, Won Kyung Kim, Jedo Oh, Me-Riong Kim, Joon-Shik Shin, Jinho Lee, In-Hyuk Ha, Sang Kook Lee
Harpagoside (1) is an iridoid glycoside isolated from the radix of Harpagophytum procumbens var. sublobatum, commonly called Devil's claw. The anti-osteoporotic effect of 1 was investigated in both in vitro cell cultures and in vivo using an ovariectomized (OVX) mouse model. Compound 1 induced bone formation by stimulating osteoblast proliferation, alkaline phosphatase activity, and mineralization in osteoblastic MC3T3-E1 cells. Treatment with 1 increased the mRNA and protein expression of bone formation biomarkers through regulation of the BMP2 and Wnt signaling pathway in MC3T3-E1 cells...
February 24, 2017: Journal of Natural Products
https://www.readbyqxmd.com/read/28078368/time-dependent-toxicity-responses-in-daphnia-magna-exposed-to-cuo-and-zno-nanoparticles
#18
Soyoun Kim, Palas Samanta, Jisu Yoo, Woo-Keun Kim, Jinho Jung
Aggregation and dissolution of CuO and ZnO nanoparticles (NPs) increased with increasing exposure time (24, 48, and 72 h). Acute toxicity of CuO NPs to Daphnia magna also increased significantly with increasing exposure time (p < 0.05), whereas exposure time did not significantly affect acute toxicity of ZnO NPs. The dissolved Cu concentration of CuO NPs was much lower than the median effective concentration (EC50) value (44 μg L(-1) at 72 h), implying that the increase in acute toxicity was caused by particles rather than by dissolved ions...
April 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28059128/c-terminus-of-hsc70-interacting-protein-chip-inhibits-adipocyte-differentiation-via-ubiquitin-and-proteasome-mediated-degradation-of-ppar%C3%AE
#19
Jung-Hoon Kim, Soyeon Shin, Jinho Seo, Eun-Woo Lee, Manhyung Jeong, Min-Sik Lee, Hyun-Ji Han, Jaewhan Song
PPARγ (Peroxisome proliferator-activated receptor γ) is a nuclear receptor involved in lipid homeostasis and related metabolic diseases. Acting as a transcription factor, PPARγ is a master regulator for adipocyte differentiation. Here, we reveal that CHIP (C-terminus of HSC70-interacting protein) suppresses adipocyte differentiation by functioning as an E3 ligase of PPARγ. CHIP directly binds to and induces ubiquitylation of the PPARγ protein, leading to proteasome-dependent degradation. Stable overexpression or knockdown of CHIP inhibited or promoted adipogenesis, respectively, in 3T3-L1 cells...
January 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28056846/biological-age-as-a-useful-index-to-predict-seventeen-year-survival-and-mortality-in-koreans
#20
Jinho Yoo, Yangseok Kim, Eo Rin Cho, Sun Ha Jee
BACKGROUND: Many studies have been conducted to quantitatively estimate biological age using measurable biomarkers. Biological age should function as a valid proxy for aging, which is closely related with future work ability, frailty, physical fitness, and/or mortality. A validation study using cohort data found biological age to be a superior index for disease-related mortality than chronological age. The purpose of this study is to demonstrate the validity of biological age as a useful index to predict a person's risk of death in the future...
January 5, 2017: BMC Geriatrics
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