keyword
https://read.qxmd.com/read/38547135/the-vertigo-trial-protocol-a-prospective-single-center-patient-blinded-study-to-evaluate-efficacy-and-safety-of-prolonged-daily-stimulation-with-a-multichannel-vestibulocochlear-implant-prototype-in-bilateral-vestibulopathy-patients
#1
JOURNAL ARTICLE
Bernd L Vermorken, Benjamin Volpe, Stan C J van Boxel, Joost J A Stultiens, Marc van Hoof, Rik Marcellis, Elke Loos, Alexander van Soest, Chris McCrum, Kenneth Meijer, Nils Guinand, Angélica Pérez Fornos, Vincent van Rompaey, Elke Devocht, Raymond van de Berg
BACKGROUND: A combined vestibular (VI) and cochlear implant (CI) device, also known as the vestibulocochlear implant (VCI), was previously developed to restore both vestibular and auditory function. A new refined prototype is currently being investigated. This prototype allows for concurrent multichannel vestibular and cochlear stimulation. Although recent studies showed that VCI stimulation enables compensatory eye, body and neck movements, the constraints in these acute study designs prevent them from creating more general statements over time...
2024: PloS One
https://read.qxmd.com/read/38546773/exploring-how-a-patient-encounter-tracking-and-learning-tool-is-used-within-general-practice-training-a-qualitative-study
#2
JOURNAL ARTICLE
Michael Bentley, Jennifer Taylor, Alison Fielding, Andrew Davey, Dominica Moad, Mieke van Driel, Parker Magin, Linda Klein
Introduction In Australian general practitioner (GP) training, feedback and reflection on in-practice experience is central to developing GP registrars' (trainees') clinical competencies. Patient encounter tracking and learning tools (PETALs) that encompass an audit of consecutive patient consultations, feedback, and reflection are used to determine registrars' in-practice exposure and have been suggested as a tool for learning within a programmatic assessment framework. However, there is limited qualitative literature on the utility of PETALs in GP training...
March 2024: Journal of Primary Health Care
https://read.qxmd.com/read/38546422/-i-m-not-getting-paid-to-give-you-a-ted-talk-on-how-my-trans-body-works-experiences-of-hysterectomy-gender-affirming-surgery-a-qualitative-study
#3
JOURNAL ARTICLE
Sarah Ingamells, Denise Steers, Claire Henry, Tai Hartley-Parsons, Sara K Filoche
OBJECTIVE: To explore the experiences of care surrounding hysterectomy as part of gender affirming surgery. METHODS: An in-depth reflexive thematic analysis from accounts by 10 out of 12 people was undertaken. Experiences were then mapped to the surgery journey as a template for developing system responsiveness. RESULTS: No one person's experience of the procedure was affirmed across the entire surgery journey. Transgender health literacy was central to inclusive practice as it mediated bodily autonomy being upheld...
March 28, 2024: International Journal of Gynaecology and Obstetrics
https://read.qxmd.com/read/38546396/differences-in-semicircular-canal-function-in-the-video-head-impulse-test-in-patients-in-the-chronic-stage-of-sudden-sensorineural-hearing-loss-with-vertigo-and-vestibular-neuritis
#4
JOURNAL ARTICLE
Natsuko Nakamichi, Tomoyuki Shiozaki, Masaharu Sakagami, Tadashi Kitahara
BACKGROUND: Sudden sensorineural hearing loss with vertigo (SHLV) and vestibular neuritis (VN) can result in prolonged dizziness. OBJECTIVES: This study aimed to compare the video head impulse test (vHIT) of patients with SHLV and VN. METHODS: Fifteen patients with SHLV and 21 patients with VN who visited the Vertigo/Dizziness Center of our hospital between December 2016 and February 2023 were included. vHIT was performed at the time of admission, and the VOR gain and catch up saccade (CUS) in the three types of semicircular canals (SCCs) were analyzed...
March 28, 2024: Acta Oto-laryngologica
https://read.qxmd.com/read/38545661/cyclooxygenase-products-contribute-to-the-exaggerated-exercise-pressor-reflex-evoked-by-static-muscle-contraction-in-male-ucd-type-2-diabetes-mellitus-rats
#5
JOURNAL ARTICLE
Milena Samora, Yu Huo, Kimber L Stanhope, Peter J Havel, Marc P Kaufman, Michelle L Harrison, Audrey J Stone
Cyclooxygenase (COX) products of arachidonic acid metabolism, specifically prostaglandins, play a role in evoking and transmitting the exercise pressor reflex in health and disease. Individuals with type 2 diabetes mellitus (T2DM) have an exaggerated exercise pressor reflex; however, the mechanisms for this exaggerated reflex are not fully understood. We aimed to determine the role played by COX products in the exaggerated exercise pressor reflex in T2DM rats. The exercise pressor reflex was evoked by static muscle contraction in unanesthetized, decerebrate, male, adult UCD-T2DM (n=8) and healthy Sprague-Dawley (n=8) rats...
March 28, 2024: Journal of Applied Physiology
https://read.qxmd.com/read/38545560/case-report-necrotizing-leukomyelitis-and-meningitis-in-a-pomeranian
#6
Koen M Santifort, Laurent Garosi, Erik A W S Weerts
A 2.5-year-old female entire Pomeranian dog was presented for acute paraparesis progressing within 2 days to paraplegia. General physical examination was unremarkable. Neurological examination showed paraplegia without nociception, a mass reflex upon testing perineal reflexes and withdrawal reflexes in the pelvic limbs and patellar hyperreflexia. Cutaneous trunci reflexes were absent caudal to the level of the 6th thoracic vertebra. Spinal hyperesthesia was present. Neuroanatomical localization was consistent with a T3-L3 myelopathy...
2024: Frontiers in Veterinary Science
https://read.qxmd.com/read/38545497/-i-felt-part-of-the-solution-a-qualitative-study-about-the-interface-between-lived-experience-advocates-professionals-and-organisations-in-the-field-of-persistent-pain
#7
JOURNAL ARTICLE
Cameron Hartley, Chris Penlington
OBJECTIVES: To elicit perspectives of people with persistent pain about their experiences working with pain management professionals and services as patient advocates and to consider implications for current models of involving patients in service development and research. DESIGN: reflexive thematic analysis from a critical realist perspective. METHODS: Online interviews were conducted individually with 10 participants who had acted as patient advocates in the field of persistent pain...
April 2024: British Journal of Pain
https://read.qxmd.com/read/38544793/evaluation-of-prenatal-calabash-chalk-geophagy-on-the-developing-brain-of-wistar-rats
#8
JOURNAL ARTICLE
Moses B Ekong, Anna Andrioli, Imaobong E Israel, Edemeka I Ifot, Samuel E Dickson, Ilaria Scambi, Paolo F Fabene, Giuseppe Bertini, Marina Bentivoglio
Calabash chalk (CaC) is an aluminium silicate hydroxide compound with heavy metal constituents, making it a potential neurotoxicant. Pregnant women often consume CaC as an antiemetic, which may interfere with the normal development of the foetal brain. Here, we evaluated the effects of CaC administration in pregnant rats on the brain of the offspring. Wistar rat dams were assigned to one of three groups: control, 200 mg/kg and 800 mg/kg of a CaC suspension. Administrations lasted 14 days (gestation days 7-20)...
June 2024: IBRO neuroscience reports
https://read.qxmd.com/read/38543149/a-common-neuronal-ensemble-in-the-lateral-habenula-regulates-ciprofol-anesthesia-in-mice
#9
JOURNAL ARTICLE
Kang Zhou, Lin-Chen Zhang, He Zhu, Bei Wen, Jia-Li Tang, Ping-Chuan Yuan, A-Fang Zhu, Yu-Guang Huang
General anesthetics were first used over 170 years ago; however, the mechanisms of how general anesthetics induce loss of consciousness (LOC) remain unclear. Ciprofol, a novel intravenous anesthetic, has been developed by incorporating cyclopropyl into the chemical structure of propofol. This modification offers the benefits of rapid onset and minimal injection pain. Recent studies have revealed that the glutamatergic neurons of the lateral habenula (LHb) play a crucial role in modulating the LOC induced by propofol and sevoflurane...
March 11, 2024: Pharmaceuticals
https://read.qxmd.com/read/38541975/a-matter-of-trust-confidentiality-in-therapeutic-relationships-during-psychological-and-medical-treatment-in-children-and-adolescents-with-mental-disorders
#10
JOURNAL ARTICLE
Johanna Xenia Kafka, Oswald David Kothgassner, Anna Felnhofer
Background: Confidentiality is a crucial ethical principle in therapy, particularly for children and adolescents, yet their perception of it remains understudied. We aimed to explore minors' perspectives and attributions on confidentiality in psychological and medical treatment. Methods: We interviewed 11 pediatric patients aged 7 to 15 and used reflexive thematic analysis to analyze their responses. Results: Four main themes were extracted from the data: (1) confidentiality and uncertainty regarding what information will be shared with clinicians and parents; (2) consequences of breaching confidentiality, encompassing breaches of confidentiality in the past and their negative effects on interactions with parents and health professionals; (3) exceptions to confidentiality, including understanding the limits of confidentiality; and (4) autonomy and self-determination, reflecting the desire for involvement in medical decisions...
March 18, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38541865/effect-of-whole-body-vibration-exercise-on-pain-disability-balance-proprioception-functional-performance-and-quality-of-life-in-people-with-non-specific-chronic-low-back-pain-a-systematic-review-and-meta-analysis
#11
REVIEW
Tasneem Zafar, Saima Zaki, Md Farhan Alam, Saurabh Sharma, Reem Abdullah Babkair, Shibili Nuhmani, Sujata Pandita
Background: Non-specific chronic low back pain (NSCLBP) presents significant treatment challenges due to its multifactorial nature. Whole-body vibration exercise (WBVE) has emerged as a potential therapeutic modality, offering benefits across various domains, including pain reduction, improved balance, and enhanced quality of life (QoL). The aim of this present systematic review and meta-analysis is to evaluate the effects of WBVE on pain, disability, balance, proprioception, functional performance, and QoL in individuals with NSCLBP...
March 13, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38541822/non-invasive-recording-of-ocular-following-responses-in-children-a-promising-tool-for-stereo-deficiency-evaluation
#12
JOURNAL ARTICLE
Aleksandar Miladinović, Christian Quaia, Miloš Ajčević, Laura Diplotti, Paola Michieletto, Agostino Accardo, Stefano Pensiero
Background: The ability to merge the two retinal images to perceive depth (stereopsis) plays an important role in human vision. Its proper development requires binocular alignment and good visual acuity in both eyes during childhood. Because treatments are more effective when applied early, early diagnosis is important. Unfortunately, assessing stereo deficiencies in infants and young children remains challenging. Recently, it has been shown that ocular-following responses (OFRs; reflexive, short-latency eye movements induced by the sudden motion of a large textured pattern) are sensitive to changes in interocular correlation, making them potentially useful for stereo deficiency assessments...
March 11, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38541256/exploring-trauma-and-violence-informed-pregnancy-care-for-karen-women-of-refugee-background-a-community-based-participatory-study
#13
JOURNAL ARTICLE
Shadow Toke, Ignacio Correa-Velez, Elisha Riggs
Women of refugee background experience poorer perinatal outcomes when compared to their local-born counterparts. Women of refugee background have often experienced trauma and are likely to encounter barriers to accessing health services in host countries which can exacerbate their recovery from trauma and contribute to poor health outcomes. Trauma- and violence-informed approaches to care offer opportunities to address barriers to pregnancy care which may, in turn, improve these poor outcomes. Trauma- and violence-informed care is a framework that acknowledges a person's experiences of trauma, recognises its impact and symptoms, and works toward resisting re-traumatisation by integrating knowledge into practice...
February 22, 2024: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/38541235/sacral-neuromodulation-device-improvement-and-current-applications-in-urology
#14
REVIEW
Marco Spilotros, Salvatore Gerbasi, Francesco Lasorsa, Gaetano de Rienzo, Lorenzo Balducci, Pasquale Ditonno, Giuseppe Lucarelli
Sacral neuromodulation (SNM) offers a therapeutic approach to urological patients suffering from idiopathic overactive bladder (OAB) syndrome, with or without incontinence and non-obstructive urinary retention (NOR), who are not responding to or are not compliant with conservative or medical therapies. The exact mechanism of action of SNM is not fully understood but modulation of the spinal cord reflexes and brain networks by peripheral afferents is regarded as the main pathway. Over the years, surgical techniques improved, leading to the development of the modern two-stage implantation technique...
March 20, 2024: Medicina
https://read.qxmd.com/read/38540555/mood-lifters-for-graduate-students-and-young-adults-a-mixed-methods-investigation-into-mechanisms-of-change-in-online-group-therapy
#15
JOURNAL ARTICLE
Elena L Pokowitz, Neema Prakash, Dennis Planaj, Sophia Oprandi, Patricia J Deldin
Mood Lifters (ML) is a dimensional, group-based, peer-led mental health program that has shown efficacy in mitigating psychopathology and promoting wellness within a variety of populations. There is not yet evidence for mechanism(s) driving these changes. Qualitative data exploring the lived experiences of participants may be a unique way to develop hypotheses about the potential mechanisms driving change. The current study used qualitative and quantitative data from the ML for Graduate Students (ML-GS) and Young Adults (ML-YA) studies to generate hypotheses regarding potential mechanisms of changes experienced in ML...
March 20, 2024: Behavioral Sciences
https://read.qxmd.com/read/38540021/zoo-visitors-most-liked-aspects-of-elephant-encounters-and-related-perceptions-of-animals-emotions-and-welfare-states-a-pragmatic-approach
#16
JOURNAL ARTICLE
Angela M Lacinak
Zoos strive to provide excellent welfare for resident animals, including those belonging to endangered species involved in captive breeding programs while addressing visitors' concerns regarding the ethics of captivity. Zoos also rely on income and support from visitors to provide exceptional care for their animal residents. It is essential, therefore, that zoos consider how visitors perceive their animals' well-being, including physical and psychological welfare. This pragmatic, qualitative research explores the aspects of training-focused enrichment activities provided for a resident herd of African elephants ( Loxodonta africana ) that visitors liked/disliked, and it assesses perceptions of the animals' emotions and welfare...
March 17, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38539175/dysphoric-milk-ejection-reflex-among-japanese-mothers-a-self-administered-survey
#17
JOURNAL ARTICLE
Yukako Moriyama, Yuko Nakao, Naoko Yamamoto, Toshimichi Oki
BACKGROUND: The dysphoric milk ejection reflex (D-MER) is a reflex that causes temporary discomfort during milk ejection. D-MER develops due to the effects of hormones involved in lactation, and it has been reported that it is a physiological symptom different from postpartum depression, but the actual situation is unknown in Japan. METHODS: This study was conducted using a self-administered, anonymous survey of mothers of children who had undergone health checkups at three years of age at five health centers in Kagoshima city and aimed to clarify the reality and perceptions of mothers regarding D-MER...
March 27, 2024: International Breastfeeding Journal
https://read.qxmd.com/read/38539097/-in-the-shower-crying%C3%A2-but-we-came-back-in-the-following-day-and-did-it-all-again-distress-and-resilience-in-care-home-staff-during-the-covid-19-pandemic-a-qualitative-interview-study
#18
JOURNAL ARTICLE
Zoë Cockshott, Siân Russell, Rachel Stocker, Jo Knight, Suzanne Mason, Barbara Hanratty, Nancy Preston
BACKGROUND: Care homes (long-term care facilities) were profoundly impacted early in the COVID-19 pandemic, both in terms of resident mortality and restrictions for infection control. This study investigated the impact on the emotional well-being of care home staff of challenges faced at this time, and the strategies used to manage them. METHODS: Semi-structured interviews conducted October 2020-June 2021 with care home staff and health service staff working with them explored the impact of the early waves of the COVID-19 pandemic (March 2020-June 2021)...
March 27, 2024: BMC Geriatrics
https://read.qxmd.com/read/38538542/occupational-performance-coaching-for-parents-of-picky-eaters-a-mixed-methods-study
#19
JOURNAL ARTICLE
Laine B Chilman, Pamela J Meredith, Nicole Southon, Ann Kennedy-Behr, Thuy Frakking, Libby Swanepoel, Michèle Verdonck
BACKGROUND/AIM: Picky eating is a common childhood phenomenon that impacts many families' occupations surrounding mealtimes. Evidence of the effectiveness of Occupational Performance Coaching (OPC) for caregivers of children suggests it may represent a useful occupation-focused intervention for parents of picky eaters. Using an OPC-targeted intervention, this study aims to report preliminary effectiveness, explore the experience of parents' participation, and investigate factors that influence the OPC intervention...
March 27, 2024: Australian Occupational Therapy Journal
https://read.qxmd.com/read/38537557/pre-and-post-operative-semicircular-canal-function-evaluated-by-video-head-impulse-test-in-patients-with-vestibular-schwannoma
#20
JOURNAL ARTICLE
Keishi Fujiwara, Shinya Morita, Hiroaki Motegi, Shigeru Yamaguchi, Yukitomo Ishi, Kimiko Hoshino, Atsushi Fukuda, Makoto Kobayashi, Yuji Nakamaru, Miki Fujimura, Akihiro Homma
OBJECTIVES: To evaluate pre- and post-operative semicircular canal function in patients with vestibular schwannoma (VS) by the video Head Impulse Test (vHIT). METHODS: Nineteen patients with VS who underwent surgery were enrolled in this study. The gain in vestibulo-ocular reflex (VOR) and the degree of scatter in catch-up saccades were examined pre- and post-operatively for the semicircular canals in VS patients. RESULTS: Ten of 19 cases (52...
March 26, 2024: Auris, Nasus, Larynx
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