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https://www.readbyqxmd.com/read/28747634/changes-of-corneal-tomography-in-patients-with-congenital-blepharoptosis
#1
Tiepei Zhu, Xin Ye, Peifang Xu, Jingyi Wang, Huina Zhang, Hailong Ni, Zhaoan Su, Juan Ye
The study aimed to evaluate the effect of drooped eyelid on corneal tomography in congenital blepharoptosis patients. Sixty-four patients with congenital blepharoptosis and 64 age- and sex- matched healthy subjects were included. According to the eyelid margin to corneal light reflex distance (MRD), eyes with congenital blepharoptosis were categorized as mild, moderate, or severe. The eyes were scanned using the rotating Scheimpflug camera. Increased topometric parameters were observed in moderate and severe blepharoptosis...
July 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28747615/isolated-congenital-megacystis-with-spontaneous-resolution-a-case-report
#2
Toshihiko Nakamura
The patient was a male infant with an antenatal diagnosis of huge intraabdominal mass. Prenatal ultrasound at 35 weeks gestation revealed a markedly enlarged cystic mass in the lower abdomen. After birth at 38 weeks, the infant was allowed to void spontaneously and passed meconium. Ultrasonography showed an enlarged bladder with wall thickness of 2.9 mm and no hydronephrosis. Voiding cystourethrograms showed no evidence of vesicoureteral reflex and posterior urethral valve. The post-void residuals were 15 mL at 11 days of life, 5 mL at 1 month and 0 mL at 5 months...
July 26, 2017: Fukushima Journal of Medical Science
https://www.readbyqxmd.com/read/28747602/inflammation-amplifier-and-gateway-reflex-the-regulation-of-inflammation-by-neuroimmune-interaction
#3
Ikuma Nakagawa, Masaaki Murakami
  Central nervous system (CNS), which is made up of brain and spinal cord, is protected from the invasion of harmful agents, such as various pathogens, chemical products or immune cells by a special structure "Blood Brain Barrier (BBB)". BBB highly preserves the homeostasis of CNS environment. On the other hand, there are many diseases in CNS regions which is associated with infection or autoimmunity, that means there may exist the "gateway" for pathogens or immune cells to attack CNS. Until recently, the molecular mechanism of the gateway formation has not been elucidated...
2017: Nihon Rinshō Men'eki Gakkai Kaishi, Japanese Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28746244/the-effect-of-unicycle-riding-course-on-trunk-strength-and-trunk-stability-functions-in-children
#4
Andrej Kocjan, Nejc Sarabon
PURPOSE: The aim of the study was to assess the effect of unicycling on trunk strength and timing of automatic stability actions of the selected trunk muscles (multifidus, obliquus externus, erector spine). METHODS: Twenty healthy 12-year-old children (12 boys, 8 girls; age 12.1 ± 0.2 yrs; body height 1.57 ± 0.05 m; body mass 52.8 ± 10.6 kg) were assigned to experimental and control group. Experimental group performed a supervised 12-session course of unicycling...
July 24, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28745818/is-repeat-botulinum-toxin-a-injection-valuable-for-neurogenic-detrusor-overactivity-a-systematic-review-and-meta-analysis
#5
REVIEW
Jianshu Ni, Xiaohu Wang, Nailong Cao, Jiemin Si, Baojun Gu
AIM: To investigate the value of repeat botulinum toxin A (BTX-A) injections in patients with neurogenic detrusor overactivity (NDO). METHODS: We searched the PubMed, EMBASE, and EBSCO databases for articles published until June 2016. Studies that reported the efficacy and safety of repeat BTX-A injections for adult patients with NDO were eligible. The effect size for each outcome was calculated as the standardized mean difference ± standard error and 95% confidence interval, and was graded as small, >0...
July 26, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28745646/reducing-state-anxiety-using-working-memory-maintenance
#6
Nicholas L Balderston, Abigail Hsiung, Jeffrey Liu, Monique Ernst, Christian Grillon
The purpose of this protocol is to explain how to examine the relationship between working memory processes and anxiety by combining the Sternberg Working Memory (WM) and the threat of shock paradigms. In the Sternberg WM paradigm, subjects are required to maintain a series of letters in the WM for a brief interval and respond by identifying whether the position of a given letter in the series matches a numerical prompt. In the threat of shock paradigm, subjects are exposed to alternating blocks where they are either at risk of receiving unpredictable presentations of a mild electric shock or are safe from the shock...
July 19, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28744976/patient-experiences-of-adjusting-to-life-in-the-first-2%C3%A2-years-after-bariatric-surgery-a-qualitative-study
#7
Y Graham, C Hayes, P K Small, K Mahawar, J Ling
There is currently little research into the experiences of those who have undergone bariatric surgery, or how surgery affects their lives and social interactions. Adopting a constructivist grounded theory methodological approach with a constant comparative analytical framework, semi-structured interviews were carried out with 18 participants (11 female, 7 male) who had undergone permanent bariatric surgical procedures 5-24 months prior to interview. Findings revealed that participants regarded social encounters after bariatric surgery as underpinned by risk...
July 26, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28744846/extubation-failure-and-tracheostomy-placement-in-children-with-acute-neurocritical-illness
#8
Ellen C Cohn, Tammy S Robertson, Stacey A Scott, Andre M Finley, Rong Huang, Darryl K Miles
BACKGROUND: There is a lack of data describing the risk factors for extubation failure (EF) or tracheostomy placement in pediatric neurocritical care (NCC) patients. METHODS: A retrospective chart review of children admitted to the pediatric intensive care unit who were intubated for >24 h with an acute neurocritical illness and had an extubation attempt. Bivariate and multivariate statistical analysis was performed to determine significant associations of demographic, neurologic, pulmonary, and clinical variables with EF and tracheostomy placement...
July 25, 2017: Neurocritical Care
https://www.readbyqxmd.com/read/28744647/antioxidant-and-antiamnestic-effects-of-potassium-comenate-and-comenic-acid-under-conditions-of-normobaric-hypoxia-with-hypercapnia
#9
L V Shurygina, E I Zlishcheva, A N Kravtsova, A A Kravtsov
Potassium comenate and comenic acid exhibit manifest and virtually identical antioxidant activity under conditions of hypoxia with hypercapnia. The effects of these drugs on conditioned reflex training with positive reinforcement differ significantly. Potassium comenate promotes retention of the learning capacity and memory in hypoxic rats at the level of intact control, that is, exhibits a pronounced protective antiamnestic effect, while comenic acid only facilitates training of the conditioned reflex with positive reinforcement...
July 26, 2017: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28743726/why-new-spinal-cord-plasticity-does-not-disrupt-old-motor-behaviors
#10
Yi Chen, Lu Chen, Yu Wang, Xiang Yang Chen, Jonathan R Wolpaw
When new motor learning changes the spinal cord, old behaviors are not impaired; their key features are preserved by additional, compensatory, plasticity. To explore the mechanisms responsible for this compensatory plasticity, we transected the spinal dorsal ascending tract (DA) before or after female rats acquired a new behavior -- operantly conditioned increase or decrease in the right soleus H-reflex - and examined an old behavior - locomotion. Neither DA transection nor H-reflex conditioning alone impaired locomotion...
July 25, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28743660/oxaliplatin-induced-peripheral-neuropathy-and-identification-of-unique-severity-groups-in-colorectal-cancer
#11
Kathleen A Griffith, Shijun Zhu, Meg Johantgen, Michael D Kessler, Cynthia Renn, Andreas S Beutler, Rahul Kanwar, Nicholas Ambulos, Guido Cavaletti, Jordi Bruna, Chiara Briani, Andreas A Argyriou, Haralabos P Kalofonos, Laura M Yerges-Armstrong, Susan G Dorsey
CONTEXT: Oxaliplatin-induced peripheral neuropathy (OIPN) is a dose limiting toxicity of oxaliplatin and affects most colorectal cancer (CRC) patients. OIPN is commonly evaluated by patient symptom report, using scales to reflect impairment. They do not discriminate between unique grouping of symptoms and signs, which impedes prompt identification of OIPN. OBJECTIVE: Our study objective was to identify clusters of symptoms and signs that differentiated underlying clinical severity and segregated patients within our population into OIPN subgroups...
July 22, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28743513/chronic-exposure-to-the-fungicide-propiconazole-behavioral-and-reproductive-evaluation-of-f1-and-f2-generations-of-male-rats
#12
Milene Leivas Vieira, Nathália Orlandini Costa, Marina Rangel F Pereira, Suzana de Fátima Paccola Mesquita, Estefânia Gastaldello Moreira, Daniela Cristina Ceccatto Gerardin
Several studies have suggested that propiconazole (PROP) may be an endocrine disruptor; possibly altering the activity of the CYP51 enzyme, which is part of the cholesterol biosynthesis pathway required for the production of sexual steroid hormones. Another PROP effect is inhibition of the aromatase enzyme that converts androgens into estrogens, which could lead to negative effects on reproductive parameters. Therefore, the present study evaluated the reproductive and developmental toxicity of PROP by exposing two generations (F1 and F2) of male rats to this fungicide, since a previous study from our lab reported that PROP has anti-estrogenic and anti-androgenic activities (Costa et al...
July 22, 2017: Toxicology
https://www.readbyqxmd.com/read/28743454/convergence-of-primary-sensory-cortex-and-cerebellar-nuclei-pathways-in-the-whisker-system
#13
REVIEW
Carmen B Schäfer, Freek E Hoebeek
To safely maneuver through the environment the brain needs to compare active sensory information with ongoing motor programs. This process occurs at various levels in the brain: at the lower level, i.e. in the spinal cord, reflexes are generated for the most primitive motor responses; at the intermediate level, i.e., in the brainstem, various nuclei co-process sensory- and motor-related inputs; and, at the higher level cerebellum and thalamo-cortical networks individually compute suitable commands for fine-tuned motor output...
July 22, 2017: Neuroscience
https://www.readbyqxmd.com/read/28742950/becoming-independent-political-participation-and-youth-transitions-in-the-scottish-referendum
#14
Maddie Breeze, Hugo Gorringe, Lynn Jamieson, Michael Rosie
Sociological debates on youth engagement with electoral politics play out against a backdrop of supposed 'decline' in civic participation (e.g. Putnam , Norris, ), in turn contextualized by theories of individualization in 'late' or 'reflexive' modernity (Beck, Giddens). However, the enfranchisement of 16 and 17 year olds in the 2014 Scottish Independence Referendum catalysed remarkably high levels of voter turnout among this youngest group, and was accompanied by apparently ongoing political engagement. We explored this engagement among a strategic sample of young 'Yes' voters, in the immediate aftermath of this exceptional political event...
July 25, 2017: British Journal of Sociology
https://www.readbyqxmd.com/read/28742873/orienting-towards-social-features-in-naturalistic-scenes-is-reflexive
#15
Lara Rösler, Albert End, Matthias Gamer
Saliency-based models of visual attention postulate that, when a scene is freely viewed, attention is predominantly allocated to those elements that stand out in terms of their physical properties. However, eye-tracking studies have shown that saliency models fail to predict gaze behavior accurately when social information is included in an image. Notably, gaze pattern analyses revealed that depictions of human beings are heavily prioritized independent of their low-level physical saliency. What remains unknown, however, is whether the prioritization of such social features is a reflexive or a voluntary process...
2017: PloS One
https://www.readbyqxmd.com/read/28742632/the-middle-ear-cleft-status-in-a-natural-cohort-with-eustachian-tube-dysfunction
#16
Udi Cinamon, Dov Albukrek, Yahav Oron, Sharon Ovnat Tamir, Abraham Goldfarb, David Dvir, Tal Marom
BACKGROUND: The Eustachian tube (ET) has a major role in the middle ear (ME) pressure homeostasis. ET dysfunction is the accepted paradigm for pressure-related ME disorders. We studied the ME status in patients with severely diminished ET opening abilities, and anticipated to find ME disorders in most of them. PATIENTS AND METHODS: ME status was evaluated in unconscious adults, who were hospitalized in a rehabilitation center with severe brain damage, requiring tracheotomy and gastrostomy...
July 24, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28742627/measurement-error-of-a-simplified-protocol-for-quantitative-sensory-tests-in-chronic-pain-patients
#17
Monika Müller, José Alberto Biurrun Manresa, Andreas Limacher, Konrad Streitberger, Peter Jüni, Ole Kæseler Andersen, Michele Curatolo
BACKGROUND AND OBJECTIVES: Large-scale application of Quantitative Sensory Tests (QST) is impaired by lacking standardized testing protocols. One unclear methodological aspect is the number of records needed to minimize measurement error. Traditionally, measurements are repeated 3 to 5 times, and their mean value is considered. When transferring QST to a clinical setting, reducing the number of records would be desirable to meet the time constraints encountered in a routine clinical environment and to reduce the testing burden to chronic pain patients...
July 24, 2017: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/28740669/impact-of-thoracic-surgery-on-esophageal-motor-function-evaluation-by-high-resolution-manometry
#18
Anja Wäsche, Arne Kandulski, Peter Malfertheiner, Sandra Riedel, Patrick Zardo, Thomas Hachenberg, Jens Schreiber
BACKGROUND: Alteration of esophageal function is a potential risk factor for postoperative complications in thoracic surgery. This prospective study investigates esophageal motility and function during and after thoracic procedures via high resolution manometry (HRM) and impedance technology with spatiotemporal representation of pressure data. METHODS: Twelve consecutive patients eligible for elective thoracic surgery underwent preoperative and postoperative (48 hours and 7 days) esophageal HRM...
June 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28739568/posterior-meningeal-artery-dmso-injection-resulting-in-reproducible-asystole-prior-to-onyx-therapy-of-a-dural-arteriovenous-fistula-a-previously-undescribed-variant-of-the-trigeminocardiac-reflex-or-a-new-phenomenon
#19
Matthew Thomas Crockett, Anthony Ernest Robinson, Harmeet Aneja, Timothy John Phillips
We describe a case of reproducible asystole during endovascular treatment of a posterior fossa dural arteriovenous fistula. Catheterisation of the posterior meningeal artery, a branch of the vertebral artery in this patient, followed by dimethyl sulfoxide injection prior to Onyx administration resulted in two episodes of asystole.To the best of our knowledge, this is the first reported case of asystole occurring during endovascular intervention in the posterior meningeal artery. This may represent a previously undescribed variant of the trigemino-cardiac reflex (TGCR) caused by chemical stimulation of small areas of trigeminally innervated posterior fossa dura...
July 24, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28739515/the-trigeminocardiac-reflex-during-the-anterior-transpetrosal-approach
#20
Shunsuke Shibao, Karam Kenawy, Hamid Borghei-Razavi, Kazunari Yoshida
BACKGROUND: The anterior transpetrosal approach (ATPA), during which the trigeminal nerve is manipulated, has a risk of eliciting the trigemino-cardiac reflex (TCR). The objective of this study was to assess the risk of the TCR during the ATPA. METHODS: The surgical records of 92 patients who had surgical treatment via the ATPA at the Keio university hospital between December 2005 and June 2015 were retrospectively analyzed. They were divided into two groups on the basis of the occurrence of the TCR during surgery, and their clinical and tumor characteristics were compared...
July 21, 2017: World Neurosurgery
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